Most cited biochemistry, genetics and molecular biology papers
- Verified
Cytosolic p53 inhibits Parkin-mediated mitophagy and promotes mitochondrial dysfunction in the mouse heart
Hoshino, A., Mita, Y., Okawa, Y., Ariyoshi, M., Iwai-Kanai, E., Ueyama, T., Ikeda, K., Ogata, T., & Matoba, S. (2013) · Nature Communications
Autophagy in Disease and TherapyMitochondrial Function and Pathology
Cited by 536
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Breast Cancer Cells Interact with Osteoblasts to Support Osteoclast Formation1
Thomas, R. J., Guise, T. A., Yin, J. J., Elliott, J., Horwood, N. J., Martin, T. J., & Gillespie, M. T. (1999) · Endocrinology
Bone Metabolism and DiseasesBone health and treatments
Cited by 536
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Chitinase-3 like-protein-1 function and its role in diseases
Zhao, T., Su, Z., Li, Y., Zhang, X., & You, Q. (2020) · Signal Transduction and Targeted Therapy
Studies on Chitinases and ChitosanasesProteoglycans and glycosaminoglycans research
Cited by 536
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PML is induced by oncogenic ras and promotes premature senescence
Ferbeyre, G., de Stanchina, E., Querido, E., Baptiste, N., Prives, C., & Lowe, S. W. (2000) · Genes & Development
Telomeres, Telomerase, and SenescenceCancer-related Molecular Pathways
Cited by 536
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Combined deficiency of ABCA1 and ABCG1 promotes foam cell accumulation and accelerates atherosclerosis in mice
Yvan-Charvet, L., Ranalletta, M., Wang, N., Han, S., Terasaka, N., Li, R., Welch, C., & Tall, A. R. (2007) · Journal of Clinical Investigation
Cholesterol and Lipid MetabolismAtherosclerosis and Cardiovascular Diseases
Cited by 536
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Inhibition of acetyl-CoA carboxylase suppresses fatty acid synthesis and tumor growth of non-small-cell lung cancer in preclinical models
Svensson, R. U., Parker, S. J., Eichner, L. J., Kolar, M. J., Wallace, M., Brun, S. N., Lombardo, P. S., Van Nostrand, J. L., Hutchins, A., Vera, L., et al. (2016) · Nature Medicine
Cancer, Lipids, and MetabolismCancer, Hypoxia, and Metabolism
Cited by 536
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Obesity-Induced Cellular Senescence Drives Anxiety and Impairs Neurogenesis
Ogrodnik, M., Zhu, Y., Langhi, L. G. P., Tchkonia, T., Krüger, P., Fielder, E., Victorelli, S., Ruswhandi, R. A., Giorgadze, N., Pirtskhalava, T., et al. (2019) · Cell Metabolism
Telomeres, Telomerase, and SenescenceNeurogenesis and neuroplasticity mechanisms
Cited by 536
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Stress-Induced Mutagenesis in Bacteria
Foster, P. L. (2007) · Critical Reviews in Biochemistry and Molecular Biology
Bacterial Genetics and BiotechnologyEvolution and Genetic Dynamics
Cited by 536
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Targeting the lactate transporter MCT1 in endothelial cells inhibits lactate-induced HIF-1 activation and tumor angiogenesis
Sonveaux, P., Copetti, T., De Saedeleer, C. J., Végran, F., Verrax, J., Kennedy, K. M., Moon, E. J., Dhup, S., Danhier, P., Frérart, F., et al. (2012) · PLoS ONE
Cancer, Hypoxia, and MetabolismAngiogenesis and VEGF in Cancer
Cited by 536
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Massively parallel functional dissection of mammalian enhancers in vivo
Patwardhan, R. P., Hiatt, J. B., Witten, D. M., Kim, M. J., Smith, R. P., May, D., Lee, C., Andrie, J. M., Lee, S.-I., Cooper, G. M., et al. (2012) · Nature Biotechnology
Genomics and Chromatin DynamicsCRISPR and Genetic Engineering
Cited by 536
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Phylogenetic Placement of Exact Amplicon Sequences Improves Associations with Clinical Information
Janssen, S., McDonald, D., Gonzalez, A., Navas-Molina, J. A., Jiang, L., Xu, Z. Z., Winker, K., Kado, D. M., Orwoll, E., Manary, M., et al. (2018) · mSystems
Genomics and Phylogenetic StudiesGut microbiota and health
Cited by 536
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Elevated Levels of Cholesterol-Rich Lipid Rafts in Cancer Cells Are Correlated with Apoptosis Sensitivity Induced by Cholesterol-Depleting Agents
Li, Y. C., Park, M. J., Ye, S.-K., Kim, C.-W., & Kim, Y.-N. (2006) · The American Journal of Pathology
Caveolin-1 and cellular processesLipid Membrane Structure and Behavior
Cited by 536
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Growth factors can influence cell growth and survival through effects on glucose metabolism
Vander Heiden, M. G., Plas, D. R., Rathmell, J. C., Fox, C. J., Harris, M. H., & Thompson, C. B. (2001) · Molecular and Cellular Biology
Cancer, Hypoxia, and MetabolismMetabolism, Diabetes, and Cancer
Cited by 536
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Control of a key transition from prostrate to erect growth in rice domestication
Tan, L., Li, X., Liu, F., Sun, X., Li, C., Zhu, Z., Fu, Y., Cai, H., Wang, X., Xie, D., et al. (2008) · Nature Genetics
Genetic Mapping and Diversity in Plants and AnimalsPlant Genetic and Mutation Studies
Cited by 536
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DeepCpG: accurate prediction of single-cell DNA methylation states using deep learning
Angermueller, C., Lee, H. J., Reik, W., & Stegle, O. (2017) · Genome Biology
Epigenetics and DNA MethylationSingle-cell and spatial transcriptomics
Cited by 536
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High-Resolution Mapping of Expression-QTLs Yields Insight into Human Gene Regulation
Veyrieras, J.-B., Kudaravalli, S., Kim, S. Y., Dermitzakis, E. T., Gilad, Y., Stephens, M., & Pritchard, J. K. (2008) · PLoS Genetics
Genetic Associations and EpidemiologyGenetic Mapping and Diversity in Plants and Animals
Cited by 536
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Control of the DNA damage checkpoint by Chk1 and Rad53 protein kinases through distinct mechanisms
Sanchez, Y., Bachant, J., Wang, H., Hu, F., Liu, D., Tetzlaff, M., & Elledge, S. J. (1999) · Science
DNA Repair MechanismsMicrotubule and mitosis dynamics
Cited by 536
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Design and Analysis of Single-Cell Sequencing Experiments
Grün, D., & van Oudenaarden, A. (2015) · Cell
Single-cell and spatial transcriptomicsGenomics and Phylogenetic Studies
Cited by 536
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Self-assembling human heart organoids for the modeling of cardiac development and congenital heart disease
Lewis-Israeli, Y. R., Wasserman, A. H., Gabalski, M. A., Volmert, B. D., Ming, Y., Ball, K. A., Yang, W., Zou, J., Ni, G., Pajares, N., et al. (2021) · Nature Communications
Pluripotent Stem Cells ResearchCongenital heart defects research
Cited by 536
- Verified
A novel di-leucine motif and a tyrosine-based motif independently mediate lysosomal targeting and endocytosis of CD3 chains
Letourneur, F., & Klausner, R. D. (1992) · Cell
Cellular transport and secretionAutophagy in Disease and Therapy
Cited by 536
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The Integrative Human Microbiome Project: Dynamic Analysis of Microbiome-Host Omics Profiles during Periods of Human Health and Disease
(2014) · Cell Host & Microbe
Gut microbiota and healthOral microbiology and periodontitis research
Cited by 536
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Enhancer loops appear stable during development and are associated with paused polymerase
Ghavi-Helm, Y., Klein, F. A., Pakozdi, T., Ciglar, L., Noordermeer, D., Huber, W., & Furlong, E. E. M. (2014) · Nature
Genomics and Chromatin DynamicsDevelopmental Biology and Gene Regulation
Cited by 536
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Highways of gene sharing in prokaryotes
Beiko, R. G., Harlow, T. J., & Ragan, M. A. (2005) · Proceedings of the National Academy of Sciences
Genomics and Phylogenetic StudiesMicrobial Community Ecology and Physiology
Cited by 535
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Caspase-11 increases susceptibility to Salmonella infection in the absence of caspase-1
Broz, P., Ruby, T., Belhocine, K., Bouley, D. M., Kayagaki, N., Dixit, V. M., & Monack, D. M. (2012) · Nature
Inflammasome and immune disordersImmune Response and Inflammation
Cited by 535
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