Most cited biochemistry, genetics and molecular biology papers
- Verified
Human-specific loss of regulatory DNA and the evolution of human-specific traits
McLean, C. Y., Reno, P. L., Pollen, A. A., Bassan, A. I., Capellini, T. D., Guenther, C., Indjeian, V. B., Lim, X., Menke, D. B., Schaar, B. T., et al. (2011) · Nature
Chromosomal and Genetic VariationsGenomic variations and chromosomal abnormalities
Cited by 535
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NF-κB blockade and oncogenic Ras trigger invasive human epidermal neoplasia
Dajee, M., Lazarov, M., Zhang, J. Y., Cai, T., Green, C. L., Russell, A. J., Marinkovich, M. P., Tao, S., Lin, Q., Kubo, Y., et al. (2003) · Nature
NF-κB Signaling PathwaysProtein Kinase Regulation and GTPase Signaling
Cited by 535
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The gut microbiome in human neurological disease: A review
Tremlett, H., Bauer, K. C., Appel‐Cresswell, S., Finlay, B. B., & Waubant, E. (2017) · Annals of Neurology
Gut microbiota and healthMultiple Sclerosis Research Studies
Cited by 535
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The hypoxic tumor microenvironment: A driving force for breast cancer progression
Semenza, G. L. (2016) · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research
Cancer, Hypoxia, and MetabolismAngiogenesis and VEGF in Cancer
Cited by 535
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Regulation and function of the mammalian tricarboxylic acid cycle
Arnold, P. K., & Finley, L. W. S. (2023) · Journal of Biological Chemistry
Cancer, Hypoxia, and MetabolismMitochondrial Function and Pathology
Cited by 535
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Mechanism and regulation of the nonsense-mediated decay pathway
Hug, N., Longman, D., & Cáceres, J. F. (2016) · Nucleic Acids Research
RNA Research and SplicingRNA regulation and disease
Cited by 535
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DNA Methylation and SETDB1/H3K9me3 Regulate Predominantly Distinct Sets of Genes, Retroelements, and Chimeric Transcripts in mESCs
Karimi, M. M., Goyal, P., Maksakova, I. A., Bilenky, M., Leung, D., Tang, J. X., Shinkai, Y., Mager, D. L., Jones, S., Hirst, M., et al. (2011) · Cell Stem Cell
Epigenetics and DNA MethylationGenomics and Chromatin Dynamics
Cited by 535
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The respiratory tract microbiome and lung inflammation: a two-way street.
Huffnagle, G. B., Dickson, R. P., & Lukacs, N. W. (2017) · Mucosal Immunology
Gut microbiota and healthOral microbiology and periodontitis research
Cited by 535
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Dual‐specificity MAP kinase phosphatases (MKPs): Shaping the outcome of MAP kinase signalling
Caunt, C. J., & Keyse, S. M. (2013) · The FEBS Journal
Protein Tyrosine PhosphatasesProtein Kinase Regulation and GTPase Signaling
Cited by 535
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DNA-SCARS: distinct nuclear structures that sustain damage-induced senescence growth arrest and inflammatory cytokine secretion
Rodier, F., Muñoz, D. P., Teachenor, R., Chu, V., Le, O., Bhaumik, D., Coppé, J.-P., Campeau, E., Beauséjour, C. M., Kim, S.-H., et al. (2011) · Journal of Cell Science
Telomeres, Telomerase, and SenescenceDNA Repair Mechanisms
Cited by 535
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Glucocorticoids, metabolism and metabolic diseases
Vegiopoulos, A., & Herzig, S. (2007) · Molecular and Cellular Endocrinology
Estrogen and related hormone effectsAdipokines, Inflammation, and Metabolic Diseases
Cited by 535
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Fructose-1,6-bisphosphatase opposes renal carcinoma progression
Li, B., Qiu, B., Lee, D. S. M., Walton, Z. E., Ochocki, J. D., Mathew, L. K., Mancuso, A., Gade, T. P. F., Keith, B., Nissim, I., et al. (2014) · Nature
Cancer, Hypoxia, and MetabolismRenal cell carcinoma treatment
Cited by 535
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Integrative approaches for finding modular structure in biological networks
Mitra, K., Carvunis, A.-R., Ramesh, S. K., & Ideker, T. (2013) · Nature Reviews Genetics
Bioinformatics and Genomic NetworksGene Regulatory Network Analysis
Cited by 535
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CTCF establishes discrete functional chromatin domains at the Hox clusters during differentiation
Narendra, V., Rocha, P. P., An, D., Raviram, R., Skok, J. A., Mazzoni, E. O., & Reinberg, D. (2015) · Science
Genomics and Chromatin DynamicsEpigenetics and DNA Methylation
Cited by 535
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Invited Review: Effects of acute exercise and exercise training on insulin resistance
Henriksen, E. J. (2002) · Journal of Applied Physiology
Metabolism, Diabetes, and CancerCardiovascular and exercise physiology
Cited by 535
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Pan-KRAS Inhibitor Disables Oncogenic Signalling and Tumour Growth
Kim, D., Herdeis, L., Rudolph, D., Zhao, Y., Böttcher, J., Vides, A., Ayala-Santos, C. I., Pourfarjam, Y., Cuevas-Navarro, A., Xue, J. Y., et al. (2023) · Nature
Protein Kinase Regulation and GTPase SignalingProtein Tyrosine Phosphatases
Cited by 534
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Mitohormesis: Promoting Health and Lifespan by Increased Levels of Reactive Oxygen Species (ROS)
Ristow, M., & Schmeisser, K. (2014) · Dose-Response
Genetics, Aging, and Longevity in Model OrganismsRedox biology and oxidative stress
Cited by 534
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Gut microbiota and metabolic syndrome
Festi, D., Schiumerini, R., Eusebi, L. H., Marasco, G., Taddia, M., & Colecchia, A. (2014) · World Journal of Gastroenterology
Gut microbiota and healthAdipokines, Inflammation, and Metabolic Diseases
Cited by 534
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Tolerance for mutations and chemical modifications in a siRNA
Amarzguioui, M. (2003) · Nucleic Acids Research
RNA Interference and Gene DeliveryDNA and Nucleic Acid Chemistry
Cited by 534
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RIPK1 maintains epithelial homeostasis by inhibiting apoptosis and necroptosis
Dannappel, M., Vlantis, K., Kumari, S., Polykratis, A., Kim, C., Wachsmuth, L., Eftychi, C., Lin, J., Corona, T., Hermance, N., et al. (2014) · Nature
Cell death mechanisms and regulationNF-κB Signaling Pathways
Cited by 534
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The deep evolution of metazoan microRNAs
Wheeler, B. M., Heimberg, A. M., Moy, V. N., Sperling, E. A., Holstein, T. W., Heber, S., & Peterson, K. J. (2009) · Evolution & Development
Developmental Biology and Gene RegulationChromosomal and Genetic Variations
Cited by 534
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An α-syntrophin-dependent pool of AQP4 in astroglial end-feet confers bidirectional water flow between blood and brain
Amiry-Moghaddam, M., Otsuka, T., Hurn, P. D., Traystman, R. J., Haug, F.-M., Froehner, S. C., Adams, M. E., Neely, J. D., Agre, P., Ottersen, O. P., et al. (2003) · Proceedings of the National Academy of Sciences
Ion Transport and Channel RegulationBarrier Structure and Function Studies
Cited by 534
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TREK-1, a K+ channel involved in neuroprotection and general anesthesia
Heurteaux, C., Guy, N., Laigle, C., Blondeau, N., Duprat, F., Mazzuca, M., Lang‐Lazdunski, L., Widmann, C., Zanzouri, M., Romey, G., et al. (2004) · The EMBO Journal
Ion channel regulation and functionEpilepsy research and treatment
Cited by 534
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Altered metabolism in cancer: insights into energy pathways and therapeutic targets
Tufail, M., Jiang, C.-H., & Li, N. (2024) · Molecular Cancer
Cancer, Hypoxia, and MetabolismMetabolism, Diabetes, and Cancer
Cited by 534
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