Most cited biochemistry, genetics and molecular biology papers
- Verified
Hypoxia signals autophagy in tumor cells via AMPK activity, independent of HIF-1, BNIP3, and BNIP3L
Papandreou, I., Lim, A. L., Laderoute, K., & Denko, N. C. (2008) · Cell Death & Differentiation
Autophagy in Disease and TherapyCancer, Hypoxia, and Metabolism
Cited by 334
- Verified
Cellular senescence: all roads lead to mitochondria
Martini, H., & Passos, J. F. (2023) · The FEBS Journal
Telomeres, Telomerase, and SenescenceMitochondrial Function and Pathology
Cited by 334
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Structure of protein phosphatase 2A core enzyme bound to tumor-inducing toxins
Xing, Y., Xu, Y., Chen, Y., Jeffrey, P. D., Chao, Y., Lin, Z., Li, Z., Strack, S., Stock, J. B., & Shi, Y. (2006) · Cell
Protein Tyrosine PhosphatasesProtein Kinase Regulation and GTPase Signaling
Cited by 334
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Metformin Inhibits the Production of Reactive Oxygen Species from NADH:Ubiquinone Oxidoreductase to Limit Induction of Interleukin-1β (IL-1β) and Boosts Interleukin-10 (IL-10) in Lipopolysaccharide (LPS)-activated Macrophages
Kelly, B., Tannahill, G. M., Murphy, M. P., & O'Neill, L. A. J. (2015) · Journal of Biological Chemistry
Inflammasome and immune disordersMetabolism, Diabetes, and Cancer
Cited by 334
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Local gene knockdown in the brain using viral-mediated RNA interference
Hommel, J. D., Sears, R. M., Georgescu, D., Simmons, D. L., & DiLeone, R. J. (2003) · Nature Medicine
RNA Interference and Gene DeliveryVirus-based gene therapy research
Cited by 334
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Lysosomal cathepsins and their regulation in aging and neurodegeneration
Stoka, V., Turk, V., & Turk, B. (2016) · Ageing Research Reviews
Autophagy in Disease and TherapyLysosomal Storage Disorders Research
Cited by 334
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Systematic discovery of cap-independent translation sequences in human and viral genomes
Weingarten-Gabbay, S., Elias-Kirma, S., Nir, R., Gritsenko, A. A., Stern-Ginossar, N., Yakhini, Z., Weinberger, A., & Segal, E. (2016) · Science
RNA and protein synthesis mechanismsRNA Research and Splicing
Cited by 334
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Osteogenesis and aging: lessons from mesenchymal stem cells
Infante, A., & Rodríguez, C. I. (2018) · Stem Cell Research & Therapy
Mesenchymal stem cell researchBone Metabolism and Diseases
Cited by 334
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Neuronal loss and brain atrophy in mice lacking cathepsins B and L
Felbor, U., Kessler, B., Mothes, W., Goebel, H. H., Ploegh, H. L., Bronson, R. T., & Olsen, B. R. (2002) · Proceedings of the National Academy of Sciences
Protease and Inhibitor MechanismsCalpain Protease Function and Regulation
Cited by 334
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Fecal SCFAs and SCFA-producing bacteria in gut microbiome of human NAFLD as a putative link to systemic T-cell activation and advanced disease
Rau, M., Rehman, A., Dittrich, M., Groen, A. K., Hermanns, H. M., Seyfried, F., Beyersdorf, N., Dandekar, T., Rosenstiel, P., & Geier, A. (2018) · United European Gastroenterology Journal
Gut microbiota and healthLiver Disease Diagnosis and Treatment
Cited by 334
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The genetic interpretation of area under the ROC curve in genomic profiling
Wray, N. R., Yang, J., Goddard, M. E., & Visscher, P. M. (2010) · PLoS Genetics
Genetic Associations and EpidemiologyGenetic and phenotypic traits in livestock
Cited by 334
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Molecular epidemiology and diagnostics of KRAS mutations in human cancer
Timar, J., & Kashofer, K. (2020) · Cancer and Metastasis Reviews
Cancer Genomics and DiagnosticsProtein Kinase Regulation and GTPase Signaling
Cited by 334
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AMPKα2 Protects Against the Development of Heart Failure by Enhancing Mitophagy via PINK1 Phosphorylation
Wang, B., Nie, J., Wu, L., Hu, Y., Wen, Z., Dong, L., Zou, M.-H., Chen, C., & Wang, D. W. (2018) · Circulation Research
Autophagy in Disease and TherapyMitochondrial Function and Pathology
Cited by 334
- Verified
Various modes of cell death induced by DNA damage
Surova, O., & Zhivotovsky, B. (2013) · Oncogene
Cell death mechanisms and regulationDNA Repair Mechanisms
Cited by 334
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The histone deacetylase inhibitor butyrate improves metabolism and reduces muscle atrophy during aging
Walsh, M. E., Bhattacharya, A., Sataranatarajan, K., Qaisar, R., Sloane, L., Rahman, M. M., Kinter, M., & Van Remmen, H. (2015) · Aging Cell
Muscle Physiology and DisordersNutrition and Health in Aging
Cited by 334
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Systemic multicompartmental effects of the gut microbiome on mouse metabolic phenotypes
Claus, S. P., Tsang, T. M., Wang, Y., Cloarec, O., Skordi, E., Martin, F., Rezzi, S., Ross, A., Kochhar, S., Holmes, E., et al. (2008) · Molecular Systems Biology
Gut microbiota and healthMetabolomics and Mass Spectrometry Studies
Cited by 334
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Evolution of individuality during the transition from unicellular to multicellular life
Michod, R. E. (2007) · Proceedings of the National Academy of Sciences
Evolution and Genetic DynamicsEvolutionary Game Theory and Cooperation
Cited by 334
- Verified
Signalling specificity of Ser/Thr protein kinases through docking-site-mediated interactions
BIONDI, R. M., & NEBREDA, A. R. (2003) · Biochemical Journal
Protein Kinase Regulation and GTPase SignalingPI3K/AKT/mTOR signaling in cancer
Cited by 334
- Verified
Mutations in the telomerase component NHP2 cause the premature ageing syndrome dyskeratosis congenita
Vulliamy, T., Beswick, R., Kirwan, M., Marrone, A., Digweed, M., Walne, A., & Dokal, I. (2008) · Proceedings of the National Academy of Sciences
Telomeres, Telomerase, and SenescenceNuclear Structure and Function
Cited by 334
- Verified
Serum level of sex steroid hormone is associated with diversity and profiles of human gut microbiome
Shin, J.-H., Park, Y.-H., Sim, M., Kim, S.-A., Joung, H., & Shin, D.-M. (2019) · Research in Microbiology
Gut microbiota and healthOral microbiology and periodontitis research
Cited by 334
- Verified
Impact of intestinal microbiota on intestinal luminal metabolome
Matsumoto, M., Kibe, R., Ooga, T., Aiba, Y., Kurihara, S., Sawaki, E., Koga, Y., & Benno, Y. (2012) · Scientific Reports
Gut microbiota and healthMetabolomics and Mass Spectrometry Studies
Cited by 334
- Verified
Stress-Induced Phosphorylation and Proteasomal Degradation of Mitofusin 2 Facilitates Mitochondrial Fragmentation and Apoptosis
Leboucher, G. P., Tsai, Y. C., Yang, M., Shaw, K. C., Zhou, M., Veenstra, T. D., Glickman, M. H., & Weissman, A. M. (2012) · Molecular Cell
Mitochondrial Function and PathologyCell death mechanisms and regulation
Cited by 334
- Verified
Using deep sequencing to characterize the biophysical mechanism of a transcriptional regulatory sequence
Kinney, J. B., Murugan, A., Callan, C. G., & Cox, E. C. (2010) · Proceedings of the National Academy of Sciences
Genomics and Chromatin DynamicsBacterial Genetics and Biotechnology
Cited by 334
- Verified
Reduction of conjugal transfer efficiency by three restriction activities of Anabaena sp. strain PCC 7120
Elhai, J., Vepritskiy, A., Muro-Pastor, A. M., Flores, E., & Wolk, C. P. (1997) · Journal of Bacteriology
Bacterial Genetics and BiotechnologyCRISPR and Genetic Engineering
Cited by 334
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