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Depression-Related Costs in Heart Failure Care
Abstract
BACKGROUND: Behavioral factors may play a role in heart failure (HF) care costs by increasing hospital readmission rates. This study sought to estimate the effect of depression on health care costs for patients hospitalized for HF. METHODS: A 3-year retrospective cohort study of a staff-model health maintenance organization. Following a first hospitalization with a primary diagnosis of HF, 1098 health maintenance organization patients were evaluated. Median annualized health care costs for 3 depression groups were identified: (1) no depression (n = 672; cost, $7474), (2) antidepressant prescription only (n = 312; cost, $11 012), and (3) antidepressant prescription and depression diagnosis recorded (n = 114; cost, $9550). Depression and HF status were determined through diagnostic, laboratory, and pharmacy records. Actual utilization and cost values were derived from administrative data. RESULTS: After adjusting for age, sex, medical comorbidity, and length of stay at index hospitalization (as proxy for HF severity), costs were 26% higher in the antidepressant prescription only group and 29% higher in the antidepressant prescription and depression diagnosis recorded group when compared with the no depression group (both P<.001). Increased inpatient and outpatient utilization contributed to the increased costs. CONCLUSION: Costs of care for patients hospitalized for HF are significantly higher for patients with evidence of depression.
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“Depressed patients with a chronic medical illness are usually sicker than their counterparts37–46 and have lower treatment adherence.37,47–51”
From Anxiety and Depression in COPD (2008) · cites this paper as [38]
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“Medical costs are significantly higher for patients with chronic medical illness and major depression than those with chronic illness alone.37,38”
From Anxiety and Depression in COPD (2008) · cites this paper as [38]
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Metadata
- Authors
- Sullivan, M., Simon, G., Spertus, J., & Russo, J.
- Affiliations
- University of Washington (US)
- Group Health Cooperative (US)
- Venue
- Archives of Internal Medicine
- Publisher
- American Medical Association (AMA)
- Published
- 2002-09-09
- Volume
- 162
- Issue
- 16
- Pages
- 1860
- ISSN
- 0003-9926 (ISSN-L)
- OpenAlex
- W2020763134
- Cited by
- 196
- References
- 35
- Citations by year
- 2026: 1 · 2025: 7 · 2024: 4 · 2023: 4 · 2022: 2 · 2021: 7 · 2020: 5 · 2019: 8 · 2018: 6 · 2017: 2 · 2016: 8 · 2015: 7 · 2014: 7 · 2013: 13 · 2012: 11
- FWCI
- 5.46
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Archives of Internal Medicine (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Institutes of Health (5k01mh001351-05)
- National Institute of Mental Health (K01 MH 01351)
- Topics
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac Health and Mental Health
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Heart Failure Treatment and Management
- Social Sciences › Economics, Econometrics and Finance › Economics and Econometrics › Health Systems, Economic Evaluations, Quality of Life
- Keywords
- depression, heart failure, health care costs, hospital readmission, antidepressant prescribing, health maintenance organizations, inpatient utilization, outpatient care utilization, behavioral risk factors
- MeSH terms
- Aged, Antidepressive Agents, Depression, Female, Health Maintenance Organizations, Health Services, Heart Failure, Hospitalization, Humans, Length of Stay, Male, Middle Aged, Primary Health Care, Retrospective Studies, United States, Cohort Studies, Multivariate Analysis, Health Care Costs
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