The Rising Prevalence of Chronic Low Back Pain
Open accessAbstract
BACKGROUND: National or state-level estimates on trends in the prevalence of chronic low back pain (LBP) are lacking. The objective of this study was to determine whether the prevalence of chronic LBP and the demographic, health-related, and health care-seeking characteristics of individuals with the condition have changed over the last 14 years. METHODS: A cross-sectional, telephone survey of a representative sample of North Carolina households was conducted in 1992 and repeated in 2006. A total of 4437 households were contacted in 1992 and 5357 households in 2006 to identify noninstitutionalized adults 21 years or older with chronic (>3 months), impairing LBP or neck pain that limits daily activities. These individuals were interviewed in more detail about their health and health care seeking. RESULTS: The prevalence of chronic, impairing LBP rose significantly over the 14-year interval, from 3.9% (95% confidence interval [CI], 3.4%-4.4%) in 1992 to 10.2% (95% CI, 9.3%-11.0%) in 2006. Increases were seen for all adult age strata, in men and women, and in white and black races. Symptom severity and general health were similar for both years. The proportion of individuals who sought care from a health care provider in the past year increased from 73.1% (95% CI, 65.2%-79.8%) to 84.0% (95% CI, 80.8%-86.8%), while the mean number of visits to all health care providers were similar (19.5 [1992] vs 19.4 [2006]). CONCLUSIONS: The prevalence of chronic, impairing LBP has risen significantly in North Carolina, with continuing high levels of disability and health care use. A substantial portion of the rise in LBP care costs over the past 2 decades may be related to this rising prevalence.
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CBP prevalence rates continue to increase.
“Despite medical advances, CBP prevalence rates continue to increase [4, 5]”
From EFFects of Exposure and Cognitive behavioral Therapy for chronic BACK pain (“EFFECT-BACK”): study protocol for a randomized controlled trial (2024) · cites this paper as [4]
The Results report that chronic low back pain prevalence in North Carolina rose from 3.9% in 1992 to 10.2% in 2006. This supports an increase over that interval, but not a continuing increase beyond 2006 or across other populations. The paper does not establish the sentence’s ‘despite medical advances’ framing. (LLM, conf=0.86)
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Cites
Lawrence, R. C., Felson, D. T., Helmick, C. G., Arnold, L. M., Choi, H. K., Deyo, R. A., Gabriel, S. E., Hirsch, R., Hochberg, M. C., Hunder, G. G., et al. (2007) · Arthritis & Rheumatism · doi:10.1002/art.23176 · Cited by 5,500 · see citing works
Lumbar Disc Disorders and Low-Back Pain: Socioeconomic Factors and Consequences
Katz, J. N. (2006) · Journal of Bone and Joint Surgery · doi:10.2106/jbjs.e.01273 · Cited by 1,655 · see citing works
Lost productive time and cost due to common pain conditions in the US workforce
Stewart, W. F. (2003) · JAMA · doi:10.1001/jama.290.18.2443 · Cited by 1,570 · see citing works
Expenditures and health status among adults with back and neck problems
Martin, B. I. (2008) · JAMA · doi:10.1001/jama.299.6.656 · Cited by 1,531 · see citing works
Sampling Methods for Random Digit Dialing
Waksberg, J. (1978) · Journal of the American Statistical Association · doi:10.1080/01621459.1978.10479995 · Cited by 1,386 · see citing works
The Prevalence of Low Back Pain: A Systematic Review of the Literature from 1966 to 1998
Walker, B. F. (2000) · Journal of Spinal Disorders · doi:10.1097/00002517-200006000-00003 · Cited by 1,143 · see citing works
United States Trends in Lumbar Fusion Surgery for Degenerative Conditions
Deyo, R. A., Gray, D. T., Kreuter, W., Mirza, S. K., & Martin, B. I. (2005) · Spine · doi:10.1097/01.brs.0000166503.37969.8a · Cited by 996 · see citing works
Back Pain Prevalence and Visit Rates
Deyo, R. A., Mirza, S. K., & Martin, B. I. (2006) · Spine · doi:10.1097/01.brs.0000244618.06877.cd · Cited by 987 · see citing works
United States’ Trends and Regional Variations in Lumbar Spine Surgery: 1992–2003
Weinstein, J. N., Lurie, J. D., Olson, P. R., Bronner, K. K., & Fisher, E. S. (2006) · Spine · doi:10.1097/01.brs.0000248132.15231.fe · Cited by 890 · see citing works
Epidemiology and Risk Factors for Spine Pain
Rubin, D. I. (2007) · Neurologic Clinics · doi:10.1016/j.ncl.2007.01.004 · Cited by 795 · see citing works
Long-Term Trends in the Use of Complementary and Alternative Medical Therapies in the United States
Kessler, R. C., Davis, R. B., Foster, D. F., Rompay, M. I. V., Walters, E. E., Wilkey, S. A., Kaptchuk, T. J., & Eisenberg, D. M. (2001) · Annals of Internal Medicine · doi:10.7326/0003-4819-135-4-200108210-00011 · Cited by 746 · see citing works
Carey, T. S., Garrett, J. M., Jackman, A., McLaughlin, C. P., Fryer, J., & Smucker, D. R. (1995) · New England Journal of Medicine · doi:10.1056/nejm199510053331406 · Cited by 562 · see citing works
Self-citationSpinal-Fusion Surgery — The Case for Restraint
Deyo, R. A., Nachemson, A., & Mirza, S. K. (2004) · New England Journal of Medicine · doi:10.1056/nejmsb031771 · Cited by 520 · see citing works
Spinal-Fusion Surgery—The Case for Restraint
Deyo, R. A., NACHEMSON, A. L., & Mirza, S. K. (2004) · The Spine Journal · doi:10.1016/j.spinee.2004.08.001 · Cited by 478 · see citing works
Ciol, M. A., Deyo, R. A., Howell, E. B., & Kreif, S. L. (1996) · Journal of the American Geriatrics Society · doi:10.1111/j.1532-5415.1996.tb00915.x · Cited by 471 · see citing works
The Growth in the Social Security Disability Rolls: A Fiscal Crisis Unfolding
Autor, D., & Duggan, M. (2006) · The Journal of Economic Perspectives · doi:10.1257/jep.20.3.71 · Cited by 447 · see citing works
Compton, W. M., Conway, K. P., Stinson, F. S., & Grant, B. F. (2006) · American Journal of Psychiatry · doi:10.1176/ajp.2006.163.12.2141 · Cited by 445 · see citing works
Back pain prevalence in US industry and estimates of lost workdays.
Guo, H., Tanaka, S., Halperin, W., & Cameron, L. L. (1999) · American Journal of Public Health · doi:10.2105/ajph.89.7.1029 · Cited by 402 · see citing works
Trends and Variations in the Use of Spine Surgery
Deyo, R. A., & Mirza, S. K. (2006) · Clinical Orthopaedics and Related Research · doi:10.1097/01.blo.0000198726.62514.75 · Cited by 374 · see citing works
van Tulder, M., Koes, B., & Bombardier, C. (2002) · Best Practice & Research Clinical Rheumatology · doi:10.1053/berh.2002.0267 · Cited by 360 · see citing works
Psychologic Distress and Low Back Pain
Croft, P. R., Papageorgiou, A. C., Ferry, S., Thomas, E., Jayson, M. I. V., & Silman, A. J. (1995) · Spine · doi:10.1097/00007632-199512150-00015 · Cited by 327 · see citing works
Increases in Lumbosacral Injections in the Medicare Population
Friedly, J. L., Chan, L. E., & Deyo, R. A. (2007) · Spine · doi:10.1097/brs.0b013e3180b9f96e · Cited by 324 · see citing works
Leboeuf‐Yde, C. (2000) · Spine · doi:10.1097/00007632-200001150-00015 · Cited by 316 · see citing works
Population-Based Trends in Volumes and Rates of Ambulatory Lumbar Spine Surgery
Gray, D. T., Deyo, R. A., Kreuter, W., Mirza, S. K., Heagerty, P. J., Comstock, B. A., & Chan, L. E. (2006) · Spine · doi:10.1097/01.brs.0000229148.63418.c1 · Cited by 304 · see citing works
Biomechanical and psychosocial risk factors for low back pain at work
Kerr, M. S., Frank, J. W., Shannon, H. S., Norman, R. W., Wells, R. P., Neumann, P., & Bombardier, C. (2001) · American Journal of Public Health · doi:10.2105/ajph.91.7.1069 · Cited by 296 · see citing works
Goldberg, M. S., Scott, S. C., & Mayo, N. E. (2000) · Spine · doi:10.1097/00007632-200004150-00016 · Cited by 267 · see citing works
Back Pain Exacerbations and Lost Productive Time Costs in United States Workers
Ricci, J. A., Stewart, W. F., Chee, E. M., Leotta, C., Foley, K. A., & Hochberg, M. C. (2006) · Spine · doi:10.1097/01.brs.0000249521.61813.aa · Cited by 265 · see citing works
Leboeuf‐Yde, C. (1999) · Spine · doi:10.1097/00007632-199907150-00012 · Cited by 245 · see citing works
Deyo, R. A. (1986) · Spine · doi:10.1097/00007632-198611000-00017 · Cited by 238 · see citing works
Carey, T. S., Evans, A. T., Hadler, N. M., Lieberman, G., Kalsbeek, W. D., Jackman, A., Fryer, J. G., & Mcnutt, R. (1996) · Spine · doi:10.1097/00007632-199602010-00018 · Cited by 238 · see citing works
Self-citationHarkness, E. F., Macfarlane, G. J., Silman, A. J., & McBeth, J. (2005) · Lara D. Veeken · doi:10.1093/rheumatology/keh599 · Cited by 211 · see citing works
Overview of the relationship between pain and obesity: What do we know? Where do we go next?
Janke, E. A., Collins, A. E., & Kozak, A. T. (2007) · The Journal of Rehabilitation Research and Development · doi:10.1682/jrrd.2006.06.0060 · Cited by 207 · see citing works
Care-Seeking Among Individuals With Chronic Low Back Pain
Carey, T. S., Evans, A. T., Hadler, N. M., Kalsbeek, W. D., McLaughlin, C. P., & Fryer, J. (1995) · Spine · doi:10.1097/00007632-199502000-00009 · Cited by 203 · see citing works
Self-citationBack pain in Britain: comparison of two prevalence surveys at an interval of 10 years
Palmer, K. (2000) · BMJ · doi:10.1136/bmj.320.7249.1577 · Cited by 203 · see citing works
Use of chiropractic services from 1985 through 1991 in the United States and Canada.
Hurwitz, E. L., Coulter, I. D., Adams, A. H., Genovese, B. J., & Shekelle, P. (1998) · American Journal of Public Health · doi:10.2105/ajph.88.5.771 · Cited by 197 · see citing works
Low Back Pain in Older Adults: Are We Utilizing Healthcare Resources Wisely?
Weiner, D. K., Kim, Y.-S., Bonino, P., & Wang, T. S. (2006) · Pain Medicine · doi:10.1111/j.1526-4637.2006.00112.x · Cited by 181 · see citing works
CHANGES IN UTILIZATION OF SPINAL FUSIONIN THE UNITED STATES
Cowan, J. A., Dimick, J. B., Wainess, R. M., Upchurch, G. R., Chandler, W. F., & Marca, F. L. (2006) · Neurosurgery · doi:10.1227/01.neu.0000219836.54861.cd · Cited by 180 · see citing works
More data on major depression as an antecedent risk factor for first onset of chronic back pain
CURRIE, S. R., & WANG, J. (2005) · Psychological Medicine · doi:10.1017/s0033291705004952 · Cited by 176 · see citing works
Which Medical Conditions Account For The Rise In Health Care Spending?
Thorpe, K. E., Florence, C., & Joski, P. (2004) · Health Affairs · doi:10.1377/hlthaff.w4.437 · Cited by 168 · see citing works
Patterns and Trends in Opioid Use among Individuals with Back Pain in the United States
Luo, X., Pietrobon, R. S., & Hey, L. A. (2004) · Spine · doi:10.1097/00007632-200404150-00012 · Cited by 151 · see citing works
Carrino, J. A., Morrison, W. B., Parker, L., Schweitzer, M. E., Levin, D. C., & Sunshine, J. H. (2002) · Radiology · doi:10.1148/radiol.2253011401 · Cited by 128 · see citing works
Back pain and obesity in the 1958 British birth cohort
Lake, J. K., Power, C., & Cole, T. J. (2000) · Journal of Clinical Epidemiology · doi:10.1016/s0895-4356(99)00155-9 · Cited by 122 · see citing works
LARSON, S. L., Clark, M. R., & Eaton, W. W. (2004) · Psychological Medicine · doi:10.1017/s0033291703001041 · Cited by 116 · see citing works
To seek or not to seek? Care-seeking behaviour among people with low-back pain
Mortimer, M., the MUSIC-Norrtälje study group, & Ahlberg, G. (2003) · Scandinavian Journal of Public Health · doi:10.1080/14034940210134086 · Cited by 116 · see citing works
Weiner, B. K. (2008) · Spine · doi:10.1097/brs.0b013e3181604572 · Cited by 100 · see citing works
Chang, Y., Singer, D. E., Wu, Y. A., Keller, R. B., & Atlas, S. J. (2005) · Journal of the American Geriatrics Society · doi:10.1111/j.1532-5415.2005.53254.x · Cited by 93 · see citing works
Is Back Pain Increasing? Results from National Surveys in Finland during 1978/9–1992
Leino, P., Berg, M., & Puska, P. (1994) · Scandinavian Journal of Rheumatology · doi:10.3109/03009749409103728 · Cited by 87 · see citing works
Heistaro, S., Vartiainen, E. A., Heliövaara, M., & Puska, P. (1998) · American Journal of Epidemiology · doi:10.1093/aje/148.7.671 · Cited by 75 · see citing works
National trends in nonoperative care for nonspecific back pain
Feuerstein, M., Marcus, S. C., & Huang, G. D. (2004) · The Spine Journal · doi:10.1016/j.spinee.2003.08.003 · Cited by 65 · see citing works
Factors associated with medical care‐seeking due to low‐back pain in scaffolders
Molano, S. M., Burdorf, A., & Elders, L. A. M. (2001) · American Journal of Industrial Medicine · doi:10.1002/ajim.1099 · Cited by 62 · see citing works
Frequency and Priority of Pain Patients' Health Care Use
Korff, M. V., Lin, E. H. B., Fenton, J. J., & Saunders, K. W. (2007) · Clinical Journal of Pain · doi:10.1097/ajp.0b013e31804ac020 · Cited by 62 · see citing works
Patterns of Care for Low Back Pain in a Working Population
IJzelenberg, W., & Burdorf, A. (2004) · Spine · doi:10.1097/01.brs.0000127188.58944.1e · Cited by 56 · see citing works
Management of Nonmalignant Pain in Home‐Dwelling Older People: A Population‐Based Survey
Pitkälä, K. H., Strandberg, T. E., & Tilvis, R. S. (2002) · Journal of the American Geriatrics Society · doi:10.1046/j.1532-5415.2002.50517.x · Cited by 56 · see citing works
Is life becoming more of a pain?
Croft, P. (2000) · BMJ · doi:10.1136/bmj.320.7249.1552 · Cited by 39 · see citing works
Back pain, a communicable disease?
Raspe, H. H., Hueppe, A., & Neuhauser, H. K. (2007) · International Journal of Epidemiology · doi:10.1093/ije/dym220 · Cited by 39 · see citing works
Is the occurrence of back pain in Germany decreasing? Two regional postal surveys a decade apart
Hüppe, A., Müller, K., & Raspe, H. H. (2006) · European Journal of Public Health · doi:10.1093/eurpub/ckl231 · Cited by 38 · see citing works
Flagged first, then by citations
Cited by
Sorted by citations
Prevention and treatment of low back pain: evidence, challenges, and promising directions
Foster, N. E., Anema, J. R., Cherkin, D., Chou, R., Cohen, S. P., Gross, D. P., Ferreira, P. H., Fritz, J. M., Koes, B. W., Peul, W., et al. (2018) · The Lancet · doi:10.1016/s0140-6736(18)30489-6 · Cited by 2,398 · see citing works
RELIEVING PAIN IN AMERICA: A BLUEPRINT FOR TRANSFORMING PREVENTION, CARE, EDUCATION, AND RESEARCH
Simon, L. S. (2012) · Journal of Pain & Palliative Care Pharmacotherapy · doi:10.3109/15360288.2012.678473 · Cited by 2,185 · see citing works
The prevalence of chronic pain in United States adults: Results of an Internet-based survey
Johannes, C. B., Le, T. K., Zhou, X., Johnston, J. A., & Dworkin, R. H. (2010) · The Journal of Pain · doi:10.1016/j.jpain.2010.07.002 · Cited by 1,252 · see citing works
Opioid Epidemic in the United States
Manchikanti, L. (2012) · Pain Physician · doi:10.36076/ppj.2012/15/es9 · Cited by 1,180 · see citing works
Prevalence of chronic low back pain: systematic review
Meucci, R. D., Fassa, A. G., & Faria, N. M. X. (2015) · Revista de Saúde Pública · doi:10.1590/s0034-8910.2015049005874 · Cited by 977 · see citing works
The Association Between Obesity and Low Back Pain: A Meta-Analysis
Shiri, R., Karppinen, J. I., Leino‐Arjas, P., Solovieva, S. A., & Viikari-Juntura, E. R. A. (2009) · American Journal of Epidemiology · doi:10.1093/aje/kwp356 · Cited by 928 · see citing works
Comprehensive Review of Epidemiology, Scope, and Impact of Spinal Pain
Manchikanti, L. (2009) · Pain Physician · doi:10.36076/ppj.2009/12/e35 · Cited by 719 · see citing works
Delitto, A., George, S. Z., Dillen, L. V., Whitman, J. M., Sowa, G., Shekelle, P., Denninger, T. R., & Godges, J. J. (2012) · Journal of Orthopaedic and Sports Physical Therapy · doi:10.2519/jospt.2012.42.4.a1 · Cited by 1,166 · see citing works
Epidemiology of Low Back Pain in Adults
Manchikanti, L., Singh, V. P., Falco, F. J. E., Benyamin, R. M., & Hirsch, J. A. (2014) · Neuromodulation Technology at the Neural Interface · doi:10.1111/ner.12018 · Cited by 642 · see citing works
Increasing Prevalence of Knee Pain and Symptomatic Knee Osteoarthritis: Survey and Cohort Data
Nguyen, U., Zhang, Y., Zhu, Y., Niu, J., Zhang, B., & Felson, D. T. (2011) · Annals of Internal Medicine · doi:10.7326/0003-4819-155-11-201112060-00004 · Cited by 615 · see citing works
George, S. Z., Fritz, J. M., Silfies, S. P., Schneider, M. J., Beneciuk, J. M., Lentz, T. A., Gilliam, J. R., Hendren, S., & Norman, K. S. (2021) · Journal of Orthopaedic & Sports Physical Therapy · doi:10.2519/jospt.2021.0304 · Cited by 607 · see citing works
Therapeutic Use, Abuse, and Nonmedical Use of Opioids: A Ten-Year Perspective
Manchikanti, L. (2010) · Pain Physician · doi:10.36076/ppj.2010/13/401 · Cited by 535 · see citing works
Chou, R., Qaseem, A., Owens, D. K., & Shekelle, P. (2011) · Annals of Internal Medicine · doi:10.7326/0003-4819-154-3-201102010-00008 · Cited by 518 · see citing works
The Epidemiology and Economic Consequences of Pain
Henschke, N., Kamper, S. J., & Maher, C. G. (2015) · Mayo Clinic Proceedings · doi:10.1016/j.mayocp.2014.09.010 · Cited by 502 · see citing works
The silent epidemic of chronic pain in older adults
Domenichiello, A. F., & Ramsden, C. E. (2019) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2019.04.006 · Cited by 438 · see citing works
Manchikanti, L. (2009) · Pain Physician · doi:10.36076/ppj.2009/12/699 · Cited by 438 · see citing works
Shmagel, A., Foley, R. N., & Ibrahim, H. N. (2016) · Arthritis Care & Research · doi:10.1002/acr.22890 · Cited by 420 · see citing works
Manchikanti, L., Abdi, S., Atluri, S. L., Benyamin, R. M., Boswell, M. V., Buenaventura, R. M., Bryce, D. A., Burks, P. A., Caraway, D. L., Calodney, A. K., et al. (2013) · PubMed · Cited by 398 · see citing works
The burden of neurological disease in the U nited S tates: A summary report and call to action
Gooch, C. L., Pracht, E. E., & Borenstein, A. R. (2017) · Annals of Neurology · doi:10.1002/ana.24897 · Cited by 389 · see citing works
ASIPP, A. (2012) · Pain Physician · doi:10.36076/ppj.2012/15/s67 · Cited by 426 · see citing works
Mechanisms of low back pain: a guide for diagnosis and therapy
Allegri, M., Montella, S., Salici, F., Valente, A., Marchesini, M., Compagnone, C., Baciarello, M., Manferdini, M. E., & Fanelli, G. C. (2016) · F1000Research · doi:10.12688/f1000research.8105.2 · Cited by 378 · see citing works
Worsening Trends in the Management and Treatment of Back Pain
Mafi, J. N., McCarthy, E. P., Davis, R. B., & Landon, B. E. (2013) · JAMA Internal Medicine · doi:10.1001/jamainternmed.2013.8992 · Cited by 359 · see citing works
Beinart, N. A., Goodchild, C. E., Weinman, J. A., Ayis, S., & Godfrey, E. L. (2013) · The Spine Journal · doi:10.1016/j.spinee.2013.08.027 · Cited by 294 · see citing works
Common brain mechanisms of chronic pain and addiction
Elman, I., & Borsook, D. (2016) · Neuron · doi:10.1016/j.neuron.2015.11.027 · Cited by 303 · see citing works
Wáng, Y. X. J., Wáng, J.-Q., & Káplár, Z. (2016) · Quantitative Imaging in Medicine and Surgery · doi:10.21037/qims.2016.04.06 · Cited by 294 · see citing works
The Role of the Vertebral End Plate in Low Back Pain
Lotz, J. C., Fields, A. J., & Liebenberg, E. C. (2013) · Global Spine Journal · doi:10.1055/s-0033-1347298 · Cited by 293 · see citing works
Teichtahl, A. J., Urquhart, D. M., Wang, Y., Wluka, A. E., Wijethilake, P., O’Sullivan, R., & Cicuttini, F. (2015) · The Spine Journal · doi:10.1016/j.spinee.2015.03.039 · Cited by 270 · see citing works
Trends in prescriptions and costs of drugs for mental disorders in England, 1998–2010
Ilyas, S., & Moncrieff, J. (2012) · The British Journal of Psychiatry · doi:10.1192/bjp.bp.111.104257 · Cited by 262 · see citing works
Fritz, J. M., Childs, J. D., Wainner, R. S., & Flynn, T. W. (2012) · Spine · doi:10.1097/brs.0b013e31825d32f5 · Cited by 259 · see citing works
Manchikanti, L., Abdi, S., Atluri, S. L., Balog, C. C., Benyamin, R. M., Boswell, M. V., Brown, K. R., Bruel, B. M., Bryce, D. A., Burks, P. A., et al. (2012) · PubMed · Cited by 243 · see citing works
Lumbar Spine Fusion for Chronic Low Back Pain Due to Degenerative Disc Disease
Phillips, F. M., Slosar, P. J., Youssef, J. A., Andersson, G. B. J., & Papatheofanis, F. J. (2013) · Spine · doi:10.1097/brs.0b013e3182877f11 · Cited by 239 · see citing works
The Mesolimbic Dopamine System in Chronic Pain and Associated Affective Comorbidities
Serafini, R. A., Pryce, K. D., & Zachariou, V. (2019) · Biological Psychiatry · doi:10.1016/j.biopsych.2019.10.018 · Cited by 237 · see citing works
Pain Trends Among American Adults, 2002–2018: Patterns, Disparities, and Correlates
Zajacova, A., Grol-Prokopczyk, H., & Zimmer, Z. (2021) · Demography · doi:10.1215/00703370-8977691 · Cited by 224 · see citing works
Manchikanti, L., Boswell, M. V., Singh, V. P., Benyamin, R. M., Fellows, B., Abdi, S., Buenaventura, R. M., Conn, A., Datta, S., Derby, R., et al. (2009) · PubMed · Cited by 229 · see citing works
Reward deficiency and anti-reward in pain chronification
Borsook, D., Linnman, C., Faria, V., Strassman, A. M., Becerra, L. R., & Elman, I. (2016) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2016.05.033 · Cited by 227 · see citing works
Muscle Control and Non-specific Chronic Low Back Pain
Russo, M., Deckers, K., Eldabe, S., Kiesel, K., Gilligan, C., Vieceli, J., & Crosby, P. (2018) · Neuromodulation: Technology at the Neural Interface · doi:10.1111/ner.12738 · Cited by 222 · see citing works
A Systematic Evaluation of Prevalence and Diagnostic Accuracy of Sacroiliac Joint Interventions
Simopoulos, T. T. (2012) · Pain Physician · doi:10.36076/ppj.2012/15/e305 · Cited by 220 · see citing works
Garcia, L. M., Birckhead, B. J., Krishnamurthy, P., Sackman, J., Mackey, I. G., Louis, R. G., Salmasi, V., Maddox, T., & Darnall, B. D. (2021) · Journal of Medical Internet Research · doi:10.2196/26292 · Cited by 225 · see citing works
Assessment of the Trends in Medical Use and Misuse of Opioid Analgesics from 2004 to 2011
Atluri, S. L. (2014) · Pain Physician · doi:10.36076/ppj.2014/17/e119 · Cited by 220 · see citing works
Overcoming negatively charged tissue barriers: Drug delivery using cationic peptides and proteins
Vedadghavami, A., Zhang, C., & Bajpayee, A. G. (2020) · Nano Today · doi:10.1016/j.nantod.2020.100898 · Cited by 213 · see citing works
Multivariate Classification of Structural MRI Data Detects Chronic Low Back Pain
Ung, H., Brown, J. E., Johnson, K. A., Younger, J., Hush, J. M., & Mackey, S. (2012) · Cerebral Cortex · doi:10.1093/cercor/bhs378 · Cited by 212 · see citing works
Hong, J., Reed, C., Novick, D., & Happich, M. (2013) · Spine · doi:10.1097/brs.0b013e318276450f · Cited by 210 · see citing works
Prevalence of low back pain in the elderly population: a systematic review
de Souza, I. M. B., Sakaguchi, T. F., Yuan, S. L. K., Matsutani, L. A., Santo, A. D. S. D. E., Pereira, C. A. D. B., & Marques, A. P. (2019) · Clinics · doi:10.6061/clinics/2019/e789 · Cited by 220 · see citing works
Gupta, N., Christiansen, C. S., Hallman, D., Korshøj, M., Carneiro, I. G., & Holtermann, A. (2015) · PLoS ONE · doi:10.1371/journal.pone.0121159 · Cited by 214 · see citing works
Benyamin, R. M. (2012) · Pain Physician · doi:10.36076/ppj.2012/15/e363 · Cited by 207 · see citing works
Chronic widespread pain prevalence in the general population: A systematic review
Andrews, P., Steultjens, M., & Riskowski, J. (2018) · European Journal of Pain · doi:10.1002/ejp.1090 · Cited by 198 · see citing works
Bunzli (2013) · doi:10.1097/ajp.0b013e31827a6dd8 · Cited by 199 · see citing works
Darnall, B. D., Roy, A., Chen, A. L., Ziadni, M. S., Keane, R. T., You, D. S., Slater, K., Poupore-King, H., Mackey, I., Kao, M.-C., et al. (2021) · JAMA Network Open · doi:10.1001/jamanetworkopen.2021.13401 · Cited by 191 · see citing works
Kim, L. H., Vail, D. G., Azad, T. D., Bentley, J., Zhang, Y., Ho, A. L., Fatemi, P., Feng, A. Y., Varshneya, K., Desai, M., et al. (2019) · JAMA Network Open · doi:10.1001/jamanetworkopen.2019.3676 · Cited by 200 · see citing works
Manchikanti, L., Singh, V. P., Falco, F. J. E., Cash, K. A., & Pampati, V. (2010) · International Journal of Medical Sciences · doi:10.7150/ijms.7.124 · Cited by 195 · see citing works
Skljarevski, V., Zhang, S., Desaiah, D., Alaka, K., Palacios, S., Miazgowski, T., & Patrick, K. (2010) · Journal of Pain · doi:10.1016/j.jpain.2010.03.002 · Cited by 194 · see citing works
Hayden, J. A., Wilson, M. N., Riley, R. D., Iles, R., Pincus, T., & Ogilvie, R. (2019) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd011284.pub2 · Cited by 188 · see citing works
Beneciuk, J. M., Bishop, M. D., Fritz, J. M., Robinson, M. E., Asal, N. R., Nisenzon, A. N., & George, S. Z. (2013) · Physical Therapy · doi:10.2522/ptj.20120207 · Cited by 185 · see citing works
Digital Support Interventions for the Self-Management of Low Back Pain: A Systematic Review
Nicholl, B. I., Sandal, L. F., Stochkendahl, M. J., McCallum, M., Suresh, N., Vasseljen, O., Hartvigsen, J., Mork, P. J., Kjær, P., Søgaard, K., et al. (2017) · Journal of Medical Internet Research · doi:10.2196/jmir.7290 · Cited by 180 · see citing works
Urine Drug Testing In Chronic Pain
Christo, P. J. (2011) · Pain Physician · doi:10.36076/ppj.2011/14/123 · Cited by 180 · see citing works
Manchikanti, L. (2016) · Pain Physician · doi:10.36076/ppj/2016.19.e365 · Cited by 182 · see citing works
A Prospective Evaluation of Complications of 10,000 Fluoroscopically Directed Epidural Injections
Manchikanti, L. (2012) · Pain Physician · doi:10.36076/ppj.2012/15/131 · Cited by 176 · see citing works
Systematic review: occupational physical activity and low back pain
Kwon, B. K., Roffey, D. M., Bishop, P., Dagenais, S., & Wai, E. K. (2011) · Occupational Medicine · doi:10.1093/occmed/kqr092 · Cited by 175 · see citing works
The musculoskeletal diagnosis cohort: examining pain and pain care among veterans
Goulet, J. L., Kerns, R. D., Bair, M., Becker, W. C., Brennan, P., Burgess, D. J., Carroll, C. M., Dobscha, S., Driscoll, M. A., Fenton, B. T., et al. (2016) · Pain · doi:10.1097/j.pain.0000000000000567 · Cited by 174 · see citing works
Association between low back pain and various everyday performances
Grabovac, I., & Dorner, T. E. (2019) · Wiener klinische Wochenschrift · doi:10.1007/s00508-019-01542-7 · Cited by 169 · see citing works
Appropriate use of lumbar imaging for evaluation of low back pain
Chou, R., Deyo, R. A., & Jarvik, J. G. (2012) · Radiologic Clinics of North America · doi:10.1016/j.rcl.2012.04.005 · Cited by 165 · see citing works
Early Physical Therapy vs Usual Care in Patients With Recent-Onset Low Back Pain
Fritz, J. M., Magel, J. S., McFadden, M., Asche, C. V., Thackeray, A., Meier, W., & Brennan, G. P. (2015) · JAMA · doi:10.1001/jama.2015.11648 · Cited by 165 · see citing works
Manchikanti, L. (2010) · Pain Physician · doi:10.36076/ppj.2010/13/199 · Cited by 163 · see citing works
Beneck, G. J., & Kulig, K. (2012) · Archives of Physical Medicine and Rehabilitation · doi:10.1016/j.apmr.2011.09.017 · Cited by 159 · see citing works
Parr, A. T. (2012) · Pain Physician · doi:10.36076/ppj.2012/15/e159 · Cited by 160 · see citing works
Low Back Pain and Lumbar Spine Osteoarthritis: How Are They Related?
Goode, A. P., Carey, T. S., & Jordan, J. M. (2013) · Current Rheumatology Reports · doi:10.1007/s11926-012-0305-z · Cited by 158 · see citing works
Self-citationEffectiveness of Long-Term Opioid Therapy for Chronic Non-Cancer Pain
Manchikanti, L. (2011) · Pain Physician · doi:10.36076/ppj.2011/14/e133 · Cited by 154 · see citing works
Manchikanti, L., Benyamin, R. M., Falco, F. J. E., Kaye, A. D., & Hirsch, J. A. (2014) · Clinical Orthopaedics and Related Research · doi:10.1007/s11999-014-3490-4 · Cited by 152 · see citing works
Lamers, E. P., Yang, A., & Zelik, K. E. (2017) · IEEE Transactions on Biomedical Engineering · doi:10.1109/tbme.2017.2761455 · Cited by 151 · see citing works
Bussières, A., Stewart, G., Zoubi, F. A., Decina, P., Descarreaux, M., Haskett, D., Hincapié, C. A., Pagé, I., Passmore, S. R., Srbely, J. Z., et al. (2018) · Journal of Manipulative and Physiological Therapeutics · doi:10.1016/j.jmpt.2017.12.004 · Cited by 149 · see citing works
Epter, R. (2009) · Pain Physician · doi:10.36076/ppj.2009/12/361 · Cited by 148 · see citing works
Hayden, J. A., Wilson, M. N., Stewart, S., Cartwright, J. L., Smith, A. O., Riley, R. D., van Tulder, M., Bendix, T., Cecchi, F., Costa, L. O. P., et al. (2020) · British Journal of Sports Medicine · doi:10.1136/bjsports-2019-101205 · Cited by 146 · see citing works
Nahin, R. L., Sayer, B., Stussman, B. J., & Feinberg, T. (2019) · Journal of Pain · doi:10.1016/j.jpain.2019.01.003 · Cited by 145 · see citing works
Kim, W. M., Lee, H. G., Jeong, C. W., Kim, C. M., & Yoon, M. H. (2010) · The Journal of Alternative and Complementary Medicine · doi:10.1089/acm.2010.0031 · Cited by 143 · see citing works
Fejer, R., & Ruhe, A. (2012) · Chiropractic & Manual Therapies · doi:10.1186/2045-709x-20-31 · Cited by 148 · see citing works
Šagát, P., Bartík, P., Prieto-González, P., Tohănean, D. I., & Knjaz, D. (2020) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph17197302 · Cited by 142 · see citing works
Sayed, D., Grider, J. S., Strand, N. H., Hagedorn, J. M., Falowski, S. M., Lam, C. M., Francio, V. T., Beall, D. P., Tomycz, N. D., Davanzo, J. R., et al. (2022) · Journal of Pain Research · doi:10.2147/jpr.s386879 · Cited by 142 · see citing works
Neuroimaging-based biomarkers for pain: state of the field and current directions
van der Miesen, M. M., Lindquist, M. A., & Wager, T. D. (2019) · PAIN Reports · doi:10.1097/pr9.0000000000000751 · Cited by 137 · see citing works
Self-assembling peptide hydrogel for intervertebral disc tissue engineering
Wan, S., Borland, S. J., Richardson, S. M., Merry, C. L. R., Saiani, A., & Gough, J. E. (2016) · Acta Biomaterialia · doi:10.1016/j.actbio.2016.09.033 · Cited by 139 · see citing works
Haskell, S. G., Ning, Y., Krebs, E., Goulet, J., Mattocks, K., Kerns, R., & Brandt, C. (2012) · The Clinical Journal of Pain · doi:10.1097/ajp.0b013e318223d951 · Cited by 137 · see citing works
Who self-identifies as disabled? An examination of impairment and contextual predictors.
Bogart, K. R., Rottenstein, A. T., Lund, E. M., & Bouchard, L. (2017) · Rehabilitation Psychology · doi:10.1037/rep0000132 · Cited by 136 · see citing works
Manchikanti, L. (2019) · Pain Physician · doi:10.36076/ppj/2019.22.s1 · Cited by 136 · see citing works
Efficacy of Auricular Therapy for Pain Management: A Systematic Review and Meta‐Analysis
Yeh, C. H., Chiang, Y., Hoffman, S. L., Liang, Z., Klem, M. L., Tam, W., Chien, L.-C., & Suen, L. K. P. (2014) · Evidence-based Complementary and Alternative Medicine · doi:10.1155/2014/934670 · Cited by 134 · see citing works
Manchikanti, L., Gharibo, C. G., Gilligan, C. J., Hirsch, J. A., Nampiaparampil, D. E., Manchikanti, K. N., Falco, F. J. E., Singh, V. P., Benyamin, R. M., Kaye, A., et al. (2015) · Surgical Neurology International · doi:10.4103/2152-7806.156598 · Cited by 134 · see citing works
A Systematic Evaluation of the Therapeutic Effectiveness of Sacroiliac Joint Interventions
Hansen, H. (2012) · Pain Physician · doi:10.36076/ppj.2012/15/e247 · Cited by 134 · see citing works
Lemmers, G. P. G., van Lankveld, W., Westert, G. P., van der Wees, P. J., & Staal, J. B. (2019) · European Spine Journal · doi:10.1007/s00586-019-05918-1 · Cited by 135 · see citing works
Chu, C., Belavý, D. L., Armbrecht, G., Bansmann, M. P., Felsenberg, D., & Guoyan Zheng, A. (2015) · PLoS ONE · doi:10.1371/journal.pone.0143327 · Cited by 130 · see citing works
Efficacy of Epidural Injections in Managing Chronic Spinal Pain: A Best Evidence Synthesis
Kaye, A. D. (2015) · Pain Physician · doi:10.36076/ppj.2015/18/e939 · Cited by 130 · see citing works
Khalil, J. G., Smuck, M. W., Koreckij, T. D., Keel, J., Beall, D. P., Goodman, B. S., Kalapos, P., Nguyen, D. T. D., & Garfin, S. R. (2019) · The Spine Journal · doi:10.1016/j.spinee.2019.05.598 · Cited by 128 · see citing works
Manchikanti, L., Abdi, S., Atluri, S. L., Balog, C. C., Benyamin, R. M., Boswell, M. V., Brown, K. R., Bruel, B. M., Bryce, D. A., Burks, P. A., et al. (2012) · PubMed · Cited by 129 · see citing works
Epidemiology of Spine Care: The Back Pain Dilemma
Friedly, J. L., Standaert, C. J., & Chan, L. E. (2010) · Physical Medicine and Rehabilitation Clinics of North America · doi:10.1016/j.pmr.2010.08.002 · Cited by 128 · see citing works
Assessment of the Growth of Epidural Injections in the Medicare Population from 2000 to 2011
Manchikanti, L. (2013) · Pain Physician · doi:10.36076/ppj.2013/16/e349 · Cited by 128 · see citing works
Traeger, A. C., Henschke, N., Hübscher, M., Williams, C. M., Kamper, S. J., Maher, C. G., Moseley, G. L., & McAuley, J. H. (2016) · PLoS Medicine · doi:10.1371/journal.pmed.1002019 · Cited by 127 · see citing works
Low back pain: critical assessment of various scales
Garg, A. X., Pathak, H., Churyukanov, M. V., Uppin, R. B., & Slobodin, T. (2020) · European Spine Journal · doi:10.1007/s00586-019-06279-5 · Cited by 128 · see citing works
Benyamin, R. M., Manchikanti, L., Parr, A. T., Diwan, S. A., Singh, V. P., Falco, F. J. E., Datta, S., Abdi, S., & Hirsch, J. A. (2012) · PubMed · Cited by 124 · see citing works
Sacroiliac joint pain: burden of disease
Cher, D., Polly, D. W., & Sigurd, B. (2014) · Medical Devices Evidence and Research · doi:10.2147/mder.s59437 · Cited by 122 · see citing works
Processing and evaluation of bioactive coatings on polymeric implants
Rabiei, A., & Sandukas, S. (2013) · Journal of Biomedical Materials Research Part A · doi:10.1002/jbm.a.34557 · Cited by 121 · see citing works
Prevalence, practice patterns, and evidence for chronic neck pain
Goode, A. P., Freburger, J. K., & Carey, T. S. (2010) · Arthritis Care & Research · doi:10.1002/acr.20270 · Cited by 120 · see citing works
Self-citationPatel, V. B., Manchikanti, L., Singh, V., Dm, S., Hayek, S. M., & Hs, S. (2009) · PubMed · Cited by 118 · see citing works
Ajimsha, M. S., Binsu, D., & Chithra, S. (2013) · Journal of Bodywork and Movement Therapies · doi:10.1016/j.jbmt.2013.05.007 · Cited by 117 · see citing works
- Authors
- Freburger, J. K., Holmes, G. M., Agans, R. P., Jackman, A. M., Darter, J. D., Wallace, A. S., Castel, L. D., Kalsbeek, W. D., & Carey, T. S.
- Affiliations
- University of North Carolina at Chapel Hill (US)
- Venue
- Archives of Internal Medicine
- Publisher
- American Medical Association (AMA)
- Published
- 2009-02-09
- Volume
- 169
- Issue
- 3
- Pages
- 251
- ISSN
- 0003-9926 (ISSN-L)
- PMC
- PMC4339077
- OpenAlex
- W2165014123
- Cited by
- 1,507
- References
- 55
- Citations by year
- 2026: 35 · 2025: 62 · 2024: 78 · 2023: 76 · 2022: 97 · 2021: 120 · 2020: 101 · 2019: 127 · 2018: 111 · 2017: 95 · 2016: 86 · 2015: 80 · 2014: 97 · 2013: 104 · 2012: 102
- FWCI
- 56.53
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Archives of Internal Medicine (publishedVersion)
- PubMed (publishedVersion)
- Europe PMC (PubMed Central) (acceptedVersion)
- PubMed Central (acceptedVersion)
- Iowa Research Online (University of Iowa) (submittedVersion)
- Funders
- National Institutes of Health (5r01ar051970-02, 2r24hd050924-06)
- Agency for Healthcare Research and Quality (T32HS000032)
- National Institute of Nursing Research (T32 NR 08856, T32NR008856)
- National Institute of Arthritis and Musculoskeletal and Skin Diseases (R0-1 AR051970)
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (R24 HD-050924)
- Topics
- Health Sciences › Medicine › Pharmacology › Musculoskeletal pain and rehabilitation
- Health Sciences › Medicine › Pathology and Forensic Medicine › Spine and Intervertebral Disc Pathology
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Pregnancy-related medical research
- Keywords
- chronic low back pain, prevalence trends, neck pain, health-seeking behavior, health care utilization, disability, racial differences, age differences, North Carolina, health care costs
- MeSH terms
- Adult, Aged, Chronic Disease, Cross-Sectional Studies, Disability Evaluation, Female, Health Surveys, Humans, Male, Middle Aged, North Carolina, Office Visits, Patient Acceptance of Health Care, Prevalence, Low Back Pain, Age Distribution, Sex Distribution, Racial Groups, Young Adult
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