Relationship Between Insulin Resistance–Associated Metabolic Parameters and Anthropometric Measurements With Sugar-Sweetened Beverage Intake and Physical Activity Levels in US Adolescents: Findings From the 1999-2004 National Health and Nutrition Examination Survey
Open accessAbstract
OBJECTIVE: To evaluate the relationship between insulin resistance-associated metabolic parameters and anthropometric measurements with sugar-sweetened beverage intake and physical activity levels. DESIGN: A cross-sectional analysis of the National Health and Nutrition Examination Survey data collected by the National Center for Health Statistics. SETTING: Nationally representative samples of US adolescents participating in the National Health and Nutrition Examination Survey during the years 1999-2004. PARTICIPANTS: A total of 6967 adolescents aged 12 to 19 years. MAIN EXPOSURE: Sugar-sweetened beverage consumption and physical activity levels. OUTCOME MEASURES: Glucose and insulin concentrations, a homeostasis model assessment of insulin resistance (HOMA-IR), total, high-density lipoprotein, and low-density lipoprotein cholesterol concentrations, triglyceride concentrations, systolic and diastolic blood pressure, waist circumference, and body mass index (calculated as weight in kilograms divided by height in meters squared) percentile for age and sex. RESULTS: Multivariate linear regression analyses showed that increased sugar-sweetened beverage intake was independently associated with increased HOMA-IR, systolic blood pressure, waist circumference, and body mass index percentile for age and sex and decreased HDL cholesterol concentrations; alternatively, increased physical activity levels were independently associated with decreased HOMA-IR, low-density lipoprotein cholesterol concentrations, and triglyceride concentrations and increased high-density lipoprotein cholesterol concentrations. Furthermore, low sugar-sweetened beverage intake and high physical activity levels appear to modify each others' effects of decreasing HOMA-IR and triglyceride concentrations and increasing high-density lipoprotein cholesterol concentrations. CONCLUSIONS: Sugar-sweetened beverage intake and physical activity levels are each independently associated with insulin resistance-associated metabolic parameters and anthropometric measurements in adolescents. Moreover, low sugar-sweetened beverage intake and high physical activity levels appear to modify each others' effects on several health-related outcome variables.
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Cross-sectional studies found a positive association between SSB consumption and insulin resistance in the whole or a subset of their study population.
“A number of cross-sectional studies found a positive association in the whole or a subset of their study population [62–65].”
From The negative impact of sugar-sweetened beverages on children’s health: an update of the literature (2018) · cites this paper as [65]
A modest number of studies reported a positive association between SSB consumption and insulin resistance risk among children and adolescents.
“A modest number of studies reported a positive association between SSB consumption and insulin resistance risk among children and adolescents, with the majority conducted cross-sectionally [62–65], one conducted longitudinally [66] and no intervention studies conducted (Table 2).”
From The negative impact of sugar-sweetened beverages on children’s health: an update of the literature (2018) · cites this paper as [65]
The majority of studies on SSB consumption and insulin resistance risk among children and adolescents were cross-sectional, one was longitudinal, and no intervention studies were conducted.
“A modest number of studies reported a positive association between SSB consumption and insulin resistance risk among children and adolescents, with the majority conducted cross-sectionally [62–65], one conducted longitudinally [66] and no intervention studies conducted (Table 2).”
From The negative impact of sugar-sweetened beverages on children’s health: an update of the literature (2018) · cites this paper as [65]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Cites
Matthews, D. R., Hosker, J. P., Rudenski, A. S., Naylor, B. A., Treacher, D. F., & Turner, R. C. (1985) · Diabetologia · doi:10.1007/bf00280883 · Cited by 31,502 · see citing works
Reduction in the incidence of type 2 diabetes with lifestyle intervention or metformin
(2002) · New England Journal of Medicine · doi:10.1056/nejmoa012512 · Cited by 19,011 · see citing works
Tuomilehto, J., Lindström, J., Eriksson, J. G., Valle, T. T., Hämäläinen, H., Ilanne-Parikka, P., Keinänen-Kiukaanniemi, S., Laakso, M., Louheranta, A., Rastas, M., et al. (2001) · New England Journal of Medicine · doi:10.1056/nejm200105033441801 · Cited by 10,873 · see citing works
Obesity and the Metabolic Syndrome in Children and Adolescents
Weiss, R., Dziura, J., Burgert, T. S., Tamborlane, W. V., Taksali, S. E., Yeckel, C. W., Allen, K., Lopes, M., Savoye, M., Morrison, J. A., et al. (2004) · New England Journal of Medicine · doi:10.1056/nejmoa031049 · Cited by 3,458 · see citing works
Ludwig, D. S., Peterson, K. E., & Gortmaker, S. L. (2001) · The Lancet · doi:10.1016/s0140-6736(00)04041-1 · Cited by 2,377 · see citing works
Cook, S., Weitzman, M., Auinger, P., Nguyen, M., & Dietz, W. H. (2003) · Archives of Pediatrics & Adolescent Medicine · doi:10.1001/archpedi.157.8.821 · Cited by 2,326 · see citing works
Self-citationNational Health and Nutrition Examination Survey
Rothwell, C. J. (2009) · Springer eBooks · doi:10.1007/978-0-387-78665-0_6177 · Cited by 2,087 · see citing works
Consumption of high-fructose corn syrup in beverages may play a role in the epidemic of obesity
Bray, G. A., Nielsen, S. J., & Popkin, B. M. (2004) · The American Journal of Clinical Nutrition · doi:10.1093/ajcn/79.4.537 · Cited by 1,990 · see citing works
Schulze, M. B. (2004) · JAMA · doi:10.1001/jama.292.8.927 · Cited by 1,639 · see citing works
Variations in DNA elucidate molecular networks that cause disease
Chen, Y., Zhu, J., Lum, P. Y., Yang, X., Pinto, S., MacNeil, D. J., Zhang, C., Lamb, J., Edwards, S., Sieberts, S. K., et al. (2008) · Nature · doi:10.1038/nature06757 · Cited by 887 · see citing works
Liquid versus solid carbohydrate: effects on food intake and body weight
DiMeglio, D., & Mattes, R. (2000) · International Journal of Obesity · doi:10.1038/sj.ijo.0801229 · Cited by 882 · see citing works
Perseghin, G., Price, T. B., Petersen, K. F., Roden, M., Cline, G. W., Gerow, K., Rothman, D. L., & Shulman, G. I. (1996) · New England Journal of Medicine · doi:10.1056/nejm199610313351804 · Cited by 699 · see citing works
Raben, A., Vasilaras, T. H., Møller, A. C., & Astrup, A. (2002) · The American Journal of Clinical Nutrition · doi:10.1093/ajcn/76.4.721 · Cited by 667 · see citing works
Morrison, J. A., Friedman, L. A., Wang, P., & Glueck, C. J. (2008) · The Journal of Pediatrics · doi:10.1016/j.jpeds.2007.09.010 · Cited by 649 · see citing works
Havel, P. J. (2005) · Nutrition Reviews · doi:10.1111/j.1753-4887.2005.tb00132.x · Cited by 607 · see citing works
Effect of the volume and intensity of exercise training on insulin sensitivity
Houmard, J. A., Tanner, C. J., Slentz, C. A., Duscha, B. D., McCartney, J. S., & Kraus, W. E. (2004) · Journal of Applied Physiology · doi:10.1152/japplphysiol.00707.2003 · Cited by 568 · see citing works
Sedentary Behavior, Physical Activity, and the Metabolic Syndrome among U.S. Adults
Ford, E. S., Kohl, H. W., Mokdad, A. H., & Ajani, U. A. (2005) · Obesity Research · doi:10.1038/oby.2005.65 · Cited by 549 · see citing works
Briefel, R., Sempos, C., McDowell, M., Chien, S., & Alaimo, K. (1997) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/65.4.1203s · Cited by 516 · see citing works
Cardiorespiratory Fitness Is Inversely Associated With the Incidence of Metabolic Syndrome
LaMonte, M. J., Barlow, C. E., Jurča, R., Kampert, J. B., Church, T. S., & Blair, S. N. (2005) · Circulation · doi:10.1161/circulationaha.104.503805 · Cited by 506 · see citing works
Prevalence and Trends of a Metabolic Syndrome Phenotype Among U.S. Adolescents, 1999–2000
Duncan, G. E., Li, S. M., & Zhou, X. (2004) · Diabetes Care · doi:10.2337/diacare.27.10.2438 · Cited by 495 · see citing works
Srinivasan, S. R., Myers, L., & Berenson, G. S. (2002) · Diabetes · doi:10.2337/diabetes.51.1.204 · Cited by 480 · see citing works
Prevalence and Determinants of Insulin Resistance Among U.S. Adolescents
Lee, J. M., Okumura, M. J., Davis, M. M., Herman, W. H., & Gurney, J. G. (2006) · Diabetes Care · doi:10.2337/dc06-0709 · Cited by 433 · see citing works
Ren, J., Semenkovich, C. F., Gulve, E. A., Gao, J. H., & Holloszy, J. O. (1994) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(17)36636-x · Cited by 416 · see citing works
Insulin Resistance Syndrome in Children
Ten, S., & Maclaren, N. K. (2004) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2004-0276 · Cited by 398 · see citing works
Obesity: Genetic, molecular, and environmental aspects
Barness, L. A., Opitz, J. M., & Gilbert‐Barness, E. (2007) · American Journal of Medical Genetics Part A · doi:10.1002/ajmg.a.32035 · Cited by 373 · see citing works
Johnson, J. L., Slentz, C. A., Houmard, J. A., Samsa, G. P., Duscha, B. D., Aiken, L. B., McCartney, J. S., Tanner, C. J., & Kraus, W. E. (2007) · The American Journal of Cardiology · doi:10.1016/j.amjcard.2007.07.027 · Cited by 347 · see citing works
Association of the metabolic syndrome with both vigorous and moderate physical activity.
Rennie, K., McCarthy, N., Yazdgerdi, S., Marmot, M., & Brunner, E. (2003) · International Journal of Epidemiology · doi:10.1093/ije/dyg179 · Cited by 320 · see citing works
Sugar-sweetened beverages and body mass index in children and adolescents: a meta-analysis
Forshee, R. A., Anderson, P. A., & Storey, M. L. (2008) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/87.6.1662 · Cited by 314 · see citing works
Beverage Intake Among Preschool Children and Its Effect on Weight Status
O’Connor, T. M., Yang, S.-J., & Nicklas, T. A. (2006) · PEDIATRICS · doi:10.1542/peds.2005-2348 · Cited by 308 · see citing works
Cardiorespiratory Fitness Levels Among US Youth 12 to 19 Years of Age
Pate, R. R., Wang, C., Dowda, M. C., Farrell, S. W., & O’Neill, J. R. (2006) · Archives of Pediatrics and Adolescent Medicine · doi:10.1001/archpedi.160.10.1005 · Cited by 261 · see citing works
Metabolic Syndrome and Its Association with Diet and Physical Activity in US Adolescents
Pan, Y., & PRATT, C. A. (2008) · Journal of the American Dietetic Association · doi:10.1016/j.jada.2007.10.049 · Cited by 254 · see citing works
Nutritional and energetic consequences of sweetened drink consumption in 6- to 13-year-old children
Mrdjenovic, G., & Levitsky, D. A. (2003) · The Journal of Pediatrics · doi:10.1067/mpd.2003.200 · Cited by 249 · see citing works
Lê, K., & Tappy, L. (2006) · Current Opinion in Clinical Nutrition & Metabolic Care · doi:10.1097/01.mco.0000232910.61612.4d · Cited by 249 · see citing works
Fructose and the Metabolic Syndrome: Pathophysiology and Molecular Mechanisms
Rutledge, A. C., & Adeli, K. (2008) · Nutrition Reviews · doi:10.1111/j.1753-4887.2007.tb00322.x · Cited by 243 · see citing works
Bell, L. M., Watts, K., Siafarikas, A., Thompson, A. M., Ratnam, N., Bulsara, M. K., Finn, J., O’Driscoll, G., GREEN, D. J., Jones, T. W., et al. (2007) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2007-0779 · Cited by 220 · see citing works
Fructose and the Metabolic Syndrome: Pathophysiology and Molecular Mechanisms
Rutledge, A. C., & Adeli, K. (2007) · Nutrition Reviews · doi:10.1301/nr.2007.jun.s13-s23 · Cited by 215 · see citing works
Ferreira, I., Henry, R. M. A., Twisk, J. W. R., van Mechelen, W., Kemper, H. C. G., & Stehouwer, C. D. A. (2005) · Archives of Internal Medicine · doi:10.1001/archinte.165.8.875 · Cited by 200 · see citing works
Andersen, L. B., Hasselstrøm, H., Grønfeldt, V., Hansen, S. E., & Froberg, K. (2004) · International Journal of Behavioral Nutrition and Physical Activity · doi:10.1186/1479-5868-1-6 · Cited by 196 · see citing works
Endurance Training and Obesity
Venables, M., & Jeukendrup, A. E. (2008) · Medicine & Science in Sports & Exercise · doi:10.1249/mss.0b013e31815f256f · Cited by 189 · see citing works
Is sugar-sweetened beverage consumption associated with increased fatness in children?
Johnson, L., Mander, A., Jones, L. R., Emmett, P. M., & Jebb, S. A. (2007) · Nutrition · doi:10.1016/j.nut.2007.05.005 · Cited by 180 · see citing works
DuBose, K. D., Eisenmann, J. C., & Donnelly, J. E. (2007) · PEDIATRICS · doi:10.1542/peds.2007-0443 · Cited by 156 · see citing works
Epidemiology of paediatric metabolic syndrome and type 2 diabetes mellitus
de Ferranti, S. D., & Osganian, S. K. (2007) · Diabetes and Vascular Disease Research · doi:10.3132/dvdr.2007.055 · Cited by 155 · see citing works
Winnick, J. J., Sherman, W. M., Habash, D. L., Stout, M. B., Failla, M. L., Belury, M. A., & Schuster, D. P. (2008) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2007-1524 · Cited by 153 · see citing works
Sugar-Sweetened Soft Drinks, Obesity, and Type 2 Diabetes
Apovian, C. M. (2004) · JAMA · doi:10.1001/jama.292.8.978 · Cited by 144 · see citing works
Swarbrick, M. M., Stanhope, K. L., Elliott, S. S., Graham, J. L., Krauss, R. M., Christiansen, M. P., Griffen, S. C., Keim, N. L., & Havel, P. J. (2008) · British Journal Of Nutrition · doi:10.1017/s0007114508968252 · Cited by 132 · see citing works
Update on the metabolic syndrome in children
Saland, J. M. (2007) · Current Opinion in Pediatrics · doi:10.1097/mop.0b013e3280208519 · Cited by 120 · see citing works
National Health and Nutrition Examination Survey, The
(2020) · Springer eBooks · doi:10.1007/978-3-030-39903-0_301242 · Cited by 105 · see citing works
Garaulet, M., Martínez, A., Victoria, F., Pérez‐Llamas, F., Anta, R. M. O., & Zamora, S. (2000) · Journal of Pediatric Gastroenterology and Nutrition · doi:10.1097/00005176-200003000-00008 · Cited by 92 · see citing works
Low physical performance in obese adolescent boys with metabolic syndrome
Török, K., Szelényi, Z., Pórszász, J., & Molnár, D. (2001) · International Journal of Obesity · doi:10.1038/sj.ijo.0801646 · Cited by 77 · see citing works
Relationships of Activity and Sugar Drink Intake on Fat Mass Development in Youths
Mundt, C., Baxter-Jones, A. D. G., Whiting, S. J., Bailey, D. A., Faulkner, R. A., & Mirwald, R. L. (2006) · Medicine & Science in Sports & Exercise · doi:10.1249/01.mss.0000227309.18902.fe · Cited by 70 · see citing works
Added thermogenic and satiety effects of a mixed nutrient vs a sugar-only beverage
St‐Onge, M., Rubiano, F., DeNino, W. F., Jones, A., Greenfield, D., FERGUSON, P. W., Akrabawi, S. S., & Heymsfield, S. B. (2004) · International Journal of Obesity · doi:10.1038/sj.ijo.0802560 · Cited by 66 · see citing works
Childhood obesity and insulin resistance
Maclaren, N. K., Gujral, S., Ten, S., & Motagheti, R. (2007) · Cell Biochemistry and Biophysics · doi:10.1007/s12013-007-0017-6 · Cited by 41 · see citing works
LaMonte, M. J., Barlow, C. E., Jurča, R., Kampert, J. B., Church, T. S., & Blair, S. N. (2005) · ACC Current Journal Review · doi:10.1016/j.accreview.2005.10.021 · Cited by 41 · see citing works
Physical Activity May Facilitate Diabetes Prevention in Adolescents
Thomas, A. S., Greene, L. F., Ard, J. D., Oster, R. A., Darnell, B. E., & Gower, B. A. (2008) · Diabetes Care · doi:10.2337/dc08-0780 · Cited by 40 · see citing works
Polygenic Contribution to Obesity: Genome-Wide Strategies Reveal New Targets
Körner, A., Kieß, W., Stümvoll, M., & Kovacs, P. L. (2008) · KARGER eBooks · doi:10.1159/000115335 · Cited by 38 · see citing works
Fatness, Fitness, and Insulin Sensitivity Among 7‐ to 9‐Year‐Old Children
Eisenmann, J. C., DuBose, K. D., & Donnelly, J. E. (2007) · Obesity · doi:10.1038/oby.2007.254 · Cited by 37 · see citing works
Effect of Diet and Physical Exercise Treatment on Insulin Resistance Syndrome of Schoolchildren
Szamosi, A., Czinner, A., Szamosi, T., Sallai, Á., Hatunic, M., Berla, Z., Tomsits, E., Almássy, Z., & Nolan, J. J. (2008) · Journal of the American College of Nutrition · doi:10.1080/07315724.2008.10719689 · Cited by 19 · see citing works
Flagged first, then by citations
Cited by
Sorted by citations
Triglycerides and Cardiovascular Disease: A Scientific Statement From the American Heart Association
Miller, M., Stone, N. J., Ballantyne, C., Bittner, V., Criqui, M. H., Ginsberg, H. N., Goldberg, A. C., Howard, W. J., Jacobson, M. S., Kris-Etherton, P. M., et al. (2011) · Circulation · doi:10.1161/cir.0b013e3182160726 · Cited by 1,871 · see citing works
Johnson, R. K., Appel, L. J., Brands, M., Howard, B. V., Lefevre, M., Lustig, R. H., Sacks, F., Steffen, L. M., & Wylie-Rosett, J. (2009) · Circulation · doi:10.1161/circulationaha.109.192627 · Cited by 1,207 · see citing works
Vos, M. B., Kaar, J. L., Welsh, J. A., Horn, L. V., Feig, D. I., Anderson, C. A. M., Patel, M. J., Muños, J. C., Krebs, N. F., Xanthakos, S. A., et al. (2016) · Circulation · doi:10.1161/cir.0000000000000439 · Cited by 584 · see citing works
The negative impact of sugar-sweetened beverages on children’s health: an update of the literature
Bleich, S. N., & Vercammen, K. A. (2018) · BMC Obesity · doi:10.1186/s40608-017-0178-9 · Cited by 309 · see citing works
Metabolic syndrome in children and adolescents
Al-Hamad, D., & Raman, V. S. (2017) · Translational Pediatrics · doi:10.21037/tp.2017.10.02 · Cited by 251 · see citing works
Rippe, J. M., & Angelopoulos, T. J. (2016) · Nutrients · doi:10.3390/nu8110697 · Cited by 234 · see citing works
To what extent have sweetened beverages contributed to the obesity epidemic?
Woodward-Lopez, G. M., Kao, J., & Ritchie, L. D. (2010) · Public Health Nutrition · doi:10.1017/s1368980010002375 · Cited by 192 · see citing works
Toward a unifying hypothesis of metabolic syndrome
Bremer, A. A., Mietus-Snyder, M., & Lustig, R. H. (2012) · PEDIATRICS · doi:10.1542/peds.2011-2912 · Cited by 186 · see citing works
Self-citationAmbrosini, G. L., Oddy, W. H., Huang, R. C., Mori, T. A., Beilin, L. J., & Jebb, S. A. (2013) · The American Journal of Clinical Nutrition · doi:10.3945/ajcn.112.051383 · Cited by 184 · see citing works
Kosova, E. C., Auinger, P., & Bremer, A. A. (2013) · Journal of the Academy of Nutrition and Dietetics · doi:10.1016/j.jand.2012.10.020 · Cited by 147 · see citing works
Self-citationImpact of Sugar-Sweetened Beverages on Blood Pressure
Malik, A. H., Akram, Y., Shetty, S. S., Malik, S., & Njike, V. Y. (2014) · The American Journal of Cardiology · doi:10.1016/j.amjcard.2014.01.437 · Cited by 145 · see citing works
Chan, T., Lin, W., Huang, H., Lee, C., Wu, P., Chiu, Y. W., Huang, C.-C., Tsai, S., Lin, C., & Lin, C. (2014) · Nutrients · doi:10.3390/nu6052088 · Cited by 130 · see citing works
Polycystic Ovary Syndrome in the Pediatric Population
Bremer, A. A. (2010) · Metabolic Syndrome and Related Disorders · doi:10.1089/met.2010.0039 · Cited by 96 · see citing works
Self-citationRodríguez, L. A., Madsen, K. A., Cotterman, C., & Lustig, R. H. (2016) · Public Health Nutrition · doi:10.1017/s1368980016000057 · Cited by 92 · see citing works
Kim, Y., & Je, Y. (2016) · Archives of cardiovascular diseases · doi:10.1016/j.acvd.2015.10.005 · Cited by 89 · see citing works
Low Copy Number of the AMY1 Locus Is Associated with Early-Onset Female Obesity in Finland
Viljakainen, H. T., Andersson‐Assarsson, J. C., Armenio, M., Pekkinen, M., Pettersson, M., Valta, H., Lipsanen‐Nyman, M., Mäkitie, O., & Lindstrand, A. (2015) · PLoS ONE · doi:10.1371/journal.pone.0131883 · Cited by 83 · see citing works
Mirmiran, P., Yuzbashian, E., Asghari, G., Hosseinpour‐Niazi, S., & Azizi, F. (2015) · Nutrition & Metabolism · doi:10.1186/s12986-015-0021-6 · Cited by 86 · see citing works
Stanhope, K. L., Griffen, S. C., Bremer, A. A., Vink, R., Schaefer, E. J., Nakajima, K., Schwarz, J., Beysen, C., Berglund, L., Keim, N. L., et al. (2011) · American Journal of Clinical Nutrition · doi:10.3945/ajcn.110.002246 · Cited by 82 · see citing works
Self-citationInsulin Resistance and Metabolic Syndrome in the Pediatric Population
Nelson, R. A., & Bremer, A. A. (2009) · Metabolic Syndrome and Related Disorders · doi:10.1089/met.2009.0068 · Cited by 79 · see citing works
Self-citationBiomarkers of intake for coffee, tea, and sweetened beverages
Rothwell, J. A., Madrid-Gambín, F., Garcia‐Aloy, M., Andrés‐Lacueva, C., Logue, C., Gallagher, A. M., Mack, C. I., Kulling, S. E., Gao, Q., Praticò, G., et al. (2018) · Genes & Nutrition · doi:10.1186/s12263-018-0607-5 · Cited by 79 · see citing works
Farhangi, M. A., Nikniaz, L., & Khodarahmi, M. (2020) · Journal of Translational Medicine · doi:10.1186/s12967-020-02511-9 · Cited by 75 · see citing works
Zuo, H., Shi, Z., Yuan, B., Dai, Y., Hu, G., Wu, G., & Hussain, A. (2012) · BMC Public Health · doi:10.1186/1471-2458-12-247 · Cited by 75 · see citing works
Fructose-Containing Sugars and Cardiovascular Disease
Rippe, J. M., & Angelopoulos, T. J. (2015) · Advances in Nutrition · doi:10.3945/an.114.008177 · Cited by 65 · see citing works
Farhangi, M. A., Tofigh, A. M., Jahangiri, L., Nikniaz, Z., & Nikniaz, L. (2022) · Pediatric Obesity · doi:10.1111/ijpo.12914 · Cited by 71 · see citing works
Katzmarzyk, P. T., Broyles, S. T., Champagne, C. M., Chaput, J., Fogelholm, M., Hu, G., Kuriyan, R., Kurpad, A. V., Lambert, E. V., Maia, J. A. R., et al. (2016) · Nutrients · doi:10.3390/nu8120770 · Cited by 62 · see citing works
Tillman, E. J., Morgan, D. A., Rahmouni, K., & Swoap, S. J. (2014) · PLoS ONE · doi:10.1371/journal.pone.0107206 · Cited by 61 · see citing works
Lowndes, J., Sinnett, S., Yu, Z., & Rippe, J. M. (2014) · Nutrients · doi:10.3390/nu6083153 · Cited by 60 · see citing works
Lowndes, J., Sinnett, S., Pardo, S., Nguyen, V., Melanson, K. J., Yu, Z., Lowther, B., & Rippe, J. M. (2014) · Nutrients · doi:10.3390/nu6031128 · Cited by 58 · see citing works
Added sugars and risk factors for obesity, diabetes and heart disease
Rippe, J. M., & Angelopoulos, T. J. (2016) · International Journal of Obesity · doi:10.1038/ijo.2016.10 · Cited by 58 · see citing works
Bremer, A. A., Auinger, P., & Byrd, R. S. (2010) · Journal of Nutrition and Metabolism · doi:10.1155/2010/196476 · Cited by 55 · see citing works
Self-citationBel‐Serrat, S., Mouratidou, T., Jiménez‐Pavón, D., Huybrechts, I., Cuenca‐García, M., Mistura, L., Gottrand, F., González‐Gross, M., Dallongeville, J., Kafatos, A., et al. (2013) · Pediatric Obesity · doi:10.1111/j.2047-6310.2013.00187.x · Cited by 53 · see citing works
Löfvenborg, J. E., Andersson, T., Carlsson, P., Dorkhan, M., Groop, L., Martinell, M., Tuomilehto, J., Wolk, A., & Carlsson, S. (2016) · European Journal of Endocrinology · doi:10.1530/eje-16-0376 · Cited by 56 · see citing works
Wang, J. W., Mark, S., Henderson, M., O'Loughlin, J., Tremblay, A., Wortman, J., Paradis, G., & Gray‐Donald, K. (2013) · Pediatric Obesity · doi:10.1111/j.2047-6310.2012.00108.x · Cited by 51 · see citing works
What is the appropriate upper limit for added sugars consumption?
Rippe, J. M., Sievenpiper, J. L., Lê, K., White, J. S., Clemens, R., & Angelopoulos, T. J. (2016) · Nutrition Reviews · doi:10.1093/nutrit/nuw046 · Cited by 51 · see citing works
Perichart‐Perera, O., Balas-Nakash, M., Rodríguez-Cano, A. M., Muñoz‐Manrique, C., Monge, A., & Vadillo‐Ortega, F. (2010) · Journal of the American Dietetic Association · doi:10.1016/j.jada.2009.10.031 · Cited by 49 · see citing works
Hur, Y., Park, H., Kang, J.-H., Lee, H. A., Song, H. J., Lee, H., & Kim, O.-H. (2015) · Nutrients · doi:10.3390/nu8010020 · Cited by 49 · see citing works
Kondaki, K., Grammatikaki, E., Jiménez-Pavón, D., De Henauw, S., González-Gross, M., Sjöstrom, M., Gottrand, F., Molnar, D., Moreno, L. A., Kafatos, A., et al. (2013) · Public Health Nutrition · doi:10.1017/s1368980012002613 · Cited by 48 · see citing works
Effects of Sugar-Sweetened Beverages on Children
Bremer, A. A., & Lustig, R. H. (2012) · Pediatric Annals · doi:10.3928/00904481-20111209-09 · Cited by 48 · see citing works
Self-citationAngelopoulos, T. J., Lowndes, J., Sinnett, S., & Rippe, J. M. (2016) · Nutrients · doi:10.3390/nu8040179 · Cited by 41 · see citing works
McKeown, N. M., Dashti, H. S., Ma, J., Haslam, D. E., Jong, J. C. K., Smith, C. E., Tanaka, T., Graff, M., Lemaître, R. N., Rybin, D. V., et al. (2017) · Diabetologia · doi:10.1007/s00125-017-4475-0 · Cited by 40 · see citing works
Giussani, M., Lieti, G., Orlando, A., Parati, G., & Genovesi, S. (2022) · Frontiers in Medicine · doi:10.3389/fmed.2022.792949 · Cited by 42 · see citing works
Food consumption and cardiovascular risk factors in E uropean children: the IDEFICS study
Bel‐Serrat, S., Mouratidou, T., Börnhorst, C., Peplies, J., Henauw, S. D., Mårild, S., Molnár, D., Siani, A., Tornaritis, M. J., Veidebaum, T., et al. (2012) · Pediatric Obesity · doi:10.1111/j.2047-6310.2012.00107.x · Cited by 39 · see citing works
Sesé, M. A., Jiménez‐Pavón, D., Gilbert, C. C., González‐Gross, M., Gottrand, F., Henauw, S. D., Breidenassel, C., Wärnberǵ, J., Widhalm, K., Molnár, D., et al. (2012) · Appetite · doi:10.1016/j.appet.2012.04.011 · Cited by 32 · see citing works
Loprinzi, P. D., Lee, I.-M. M., Andersen, R. E., Crespo, C. J., & Smit, E. (2014) · American Journal of Health Promotion · doi:10.4278/ajhp.140213-quan-71 · Cited by 30 · see citing works
Targeting skeletal muscle mitochondria to prevent type 2 diabetes in youth
Gordon, J. W., Dolinsky, V. W., Mughal, W., Gordon, G. R., & McGavock, J. (2015) · Biochemistry and Cell Biology · doi:10.1139/bcb-2015-0012 · Cited by 30 · see citing works
Μanios, Y., Kourlaba, G., Grammatikaki, E., Koubitski, A., Siatitsa, P.-E., Vandorou, A., Kyriakou, K., Dede, V., & Moschonis, G. (2010) · European Journal of Clinical Nutrition · doi:10.1038/ejcn.2010.172 · Cited by 30 · see citing works
Nikniaz, L., Abbasalizad‐Farhangi, M., Vajdi, M., & Nikniaz, Z. (2021) · Pediatric Obesity · doi:10.1111/ijpo.12782 · Cited by 29 · see citing works
Fardet, A., & Richonnet, C. (2019) · Critical Reviews in Food Science and Nutrition · doi:10.1080/10408398.2019.1682512 · Cited by 29 · see citing works
Tipton, J. A. (2013) · Journal of Pediatric Nursing · doi:10.1016/j.pedn.2013.06.006 · Cited by 28 · see citing works
Hypertriglyceridemia in Diabetes Mellitus: Implications for Pediatric Care
Hartz, J. C., de Ferranti, S. D., & Gidding, S. S. (2018) · Journal of the Endocrine Society · doi:10.1210/js.2018-00079 · Cited by 27 · see citing works
Santiago‐Torres, M., Cui, Y., Adams, A. K., Allen, D. B., Carrel, A. L., Guo, J. Y., Delgado‐Rendon, A., LaRowe, T. L., & Schoeller, D. A. (2016) · Pediatric Obesity · doi:10.1111/ijpo.12020 · Cited by 26 · see citing works
Dietary intake and prospective changes in cardiometabolic risk factors in children and youth
Setayeshgar, S., Ekwaru, J. P., Maximova, K., Majumdar, S. R., Storey, K., McGavock, J., & Veugelers, P. J. (2016) · Applied Physiology, Nutrition, and Metabolism · doi:10.1139/apnm-2016-0215 · Cited by 26 · see citing works
Bremer, A. A., Byrd, R. S., & Auinger, P. (2010) · Clinical Pediatrics · doi:10.1177/0009922810379043 · Cited by 24 · see citing works
Self-citationZhang, B., Shi, H., Cai, W., Yang, B., & Xiu, W. (2025) · Frontiers in Endocrinology · doi:10.3389/fendo.2025.1512642 · Cited by 24 · see citing works
Wang, J. (2014) · Applied Physiology, Nutrition, and Metabolism · doi:10.1139/apnm-2013-0456 · Cited by 23 · see citing works
Monnard, C. R., & Grasser, E. K. (2018) · Advances in Nutrition · doi:10.1093/advances/nmx023 · Cited by 23 · see citing works
Ruff, R. R., & Zhen, C. (2015) · Annals of Epidemiology · doi:10.1016/j.annepidem.2014.12.008 · Cited by 22 · see citing works
Hilger-Kolb, J., Bosle, C., Motoc, I., & Hoffmann, K. (2017) · Nutrition Journal · doi:10.1186/s12937-017-0300-3 · Cited by 22 · see citing works
Terry‐McElrath, Y. M., O’Malley, P. M., & Johnston, L. D. (2011) · Journal of School Health · doi:10.1111/j.1746-1561.2011.00666.x · Cited by 21 · see citing works
Racial trends in sugar-sweetened beverage consumption among US adolescents: 1988–2004
Bremer, A. A., Byrd, R. S., & Auinger, P. (2011) · International Journal of Adolescent Medicine and Health · doi:10.1515/ijamh.2011.056 · Cited by 20 · see citing works
Self-citationZhao, Y., Feng, Y., Zeng, Y., Di, W., Luo, X., Wu, X., Guan, R., Xu, L., Yang, X., Li, Y., et al. (2023) · Critical Reviews in Food Science and Nutrition · doi:10.1080/10408398.2023.2213330 · Cited by 20 · see citing works
Spruijt-Metz, D., Belcher, B., Hsu, Y.-W., McClain, A. D., Chou, C.-P., Nguyen-Rodriguez, S., Weigensberg, M., & Goran, M. (2013) · Diabetes Care · doi:10.2337/dc13-0083 · Cited by 18 · see citing works
Bhatnagar, D., & Bhatnagar, P. (2012) · Current Opinion in Lipidology · doi:10.1097/mol.0b013e328355ee48 · Cited by 21 · see citing works
Obesity and Metabolic Care of Children of South Asian Ethnicity in Western Society
Sivasubramanian, R., Malhotra, S., Fitch, A., & Singhal, V. (2021) · Children · doi:10.3390/children8060447 · Cited by 19 · see citing works
Metabolic Syndrome in Children and Adolescents
Chung, L. Y., & Rhie, Y. (2022) · Ewha Medical Journal · doi:10.12771/emj.2022.e13 · Cited by 23 · see citing works
Ruff, R. R., Akhund, A., Mezzacca, T. A., & Kansagra, S. M. (2014) · Journal of Community Health · doi:10.1007/s10900-014-9865-3 · Cited by 17 · see citing works
Jiménez‐Pavón, D., Sesé, M. A., Huybrechts, I., Cuenca‐García, M., Palacios, G., Ruiz, J. R., Breidenassel, C., Leclercq, C., Béghin, L., Plada, M., et al. (2013) · British Journal Of Nutrition · doi:10.1017/s0007114513001153 · Cited by 17 · see citing works
Tipton, J. A. (2014) · Journal of Pediatric Nursing · doi:10.1016/j.pedn.2014.07.006 · Cited by 17 · see citing works
Childhood Obesity and Insulin Resistance: How Should It Be Managed?
Ho, M. M., Garnett, S. P., & Baur, L. A. (2014) · Current Treatment Options in Cardiovascular Medicine · doi:10.1007/s11936-014-0351-0 · Cited by 17 · see citing works
de Boer, E. C., de Rooij, S. R., Olthof, M. R., & Vrijkotte, T. G. M. (2018) · Clinical Nutrition ESPEN · doi:10.1016/j.clnesp.2018.08.020 · Cited by 16 · see citing works
Diet and Exercise in Pediatric Liver Transplant Recipients
Chambers, J. H., Zerofsky, M. S., Lustig, R. H., Rosenthal, P. J., & Perito, E. R. (2018) · Journal of Pediatric Gastroenterology and Nutrition · doi:10.1097/mpg.0000000000002150 · Cited by 15 · see citing works
Wu, P., Tsai, S., Lee, C., Lin, W., Chin, Y., Huang, H.-L., Seal, D. W., Chen, T., & Lee, C. (2021) · International Journal of Obesity · doi:10.1038/s41366-021-00745-1 · Cited by 15 · see citing works
Added and Free Sugars Intake and Metabolic Biomarkers in Japanese Adolescents
Okuda, M., Fujiwara, A., & Sasaki, S. (2020) · Nutrients · doi:10.3390/nu12072046 · Cited by 14 · see citing works
Sugar and Salt in the Pathogenesis of Elevated Blood Pressure
Stolarz‐Skrzypek, K. (2011) · Hypertension · doi:10.1161/hypertensionaha.110.167429 · Cited by 13 · see citing works
Hsu, Y.-J., Lee, M., Huang, C., & Ho, C.-S. (2020) · International Journal of Medical Sciences · doi:10.7150/ijms.52347 · Cited by 12 · see citing works
Kim, J. H., & Lim, J. S. (2022) · Life · doi:10.3390/life12091404 · Cited by 13 · see citing works
Bingham, C. M. L., Lahti‐Koski, M., Absetz, P., Puukka, P. J., Kinnunen, M. I., PIHLAJAMÄKI, H. K., Sahi, T., Uutela, A. K., & Jallinoja, P. T. (2011) · Public Health Nutrition · doi:10.1017/s1368980011003351 · Cited by 12 · see citing works
Bilog, N. C., Ndongo, J. M., Lele, E. C. B., Guessogo, W. R., Assomo-Ndemba, P. B., Ahmadou, Etaga, N. B., Biloa, Y. J. M., Bwegne, J. G. B. N., Temfemo, A., et al. (2023) · Journal of Health Population and Nutrition · doi:10.1186/s41043-023-00415-0 · Cited by 11 · see citing works
The, N. S., Couch, S. C., Urbina, E. M., Crandell, J., Liese, A. D., Dabelea, D., Kim, G. J., Tooze, J. A., Lawrence, J. M., & Mayer‐Davis, E. J. (2019) · Nutrients · doi:10.3390/nu11081752 · Cited by 12 · see citing works
Fructose, High Fructose Corn Syrup, Sucrose, and Health: Modern Scientific Understandings
Rippe, J. M. (2014) · Springer eBooks · doi:10.1007/978-1-4899-8077-9_1 · Cited by 11 · see citing works
Environmental risk factors and metabolic syndrome components in overweight youngsters
Múnera, N. E., Uscátegui, R. M., Parra, B. E., Correa, L. M. M., Villada, F. A. P., Velásquez, C. M., Estrada, A., Bedoya, G., Parra, V., Contreras, A. M. M., et al. (2011) · Biomédica · doi:10.7705/biomedica.v32i1.595 · Cited by 15 · see citing works
Predictors of Childhood Obesity and Pathogenesis of Comorbidities
Freemark, M. (2014) · Pediatric Annals · doi:10.3928/00904481-20140825-06 · Cited by 10 · see citing works
Effect of Lifestyle, Aging, and Phytochemicals on the Onset of Neurological Disorders
Farooqui, A. A. (2012) · Springer eBooks · doi:10.1007/978-1-4614-3804-5_1 · Cited by 10 · see citing works
Zhang, Y., Wu, X., Wang, Q., Zong, Q., Wang, R., Li, T., Tao, S., & Tao, F. (2021) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2021.573168 · Cited by 9 · see citing works
Just a spoonful of sugar helps the blood pressure go up
Nguyen, S. N., & Lustig, R. H. (2010) · Expert Review of Cardiovascular Therapy · doi:10.1586/erc.10.120 · Cited by 9 · see citing works
Adolescent’s Health Behaviors and Risk for Insulin Resistance: A Review of the Literature
Kaar, J. L., Simon, S. L., Schmiege, S. J., Nadeau, K. J., & Kelsey, M. M. (2017) · Current Diabetes Reports · doi:10.1007/s11892-017-0881-4 · Cited by 8 · see citing works
Nutrition, Lifestyle, and Hypertension
Lin, P., Tyson, C. C., Batch, B. C., & Svetkey, L. P. (2017) · Elsevier eBooks · doi:10.1016/b978-0-12-802928-2.00028-x · Cited by 11 · see citing works
O’Neil, C. E., Nicklas, T. A., Liu, Y., & Berenson, G. S. (2013) · Journal of Human Nutrition and Dietetics · doi:10.1111/jhn.12200 · Cited by 8 · see citing works
Andersen, E., Høstmark, A. T., Lorentzen, C., & Anderssen, S. A. (2011) · Norsk Epidemiologi · doi:10.5324/nje.v20i2.1343 · Cited by 8 · see citing works
Klonoff, D. C. (2009) · Journal of Diabetes Science and Technology · doi:10.1177/193229680900300301 · Cited by 8 · see citing works
Relative Children’s Lipid Accumulation Product Is a Novel Indicator for Metabolic Syndrome
Zhang, L., Zhang, Z., Wang, B., Yuan, Y., Sun, L., Gao, H., & Fu, L. (2021) · Frontiers in Endocrinology · doi:10.3389/fendo.2021.645825 · Cited by 7 · see citing works
Ong, J., Roem, J., Ducharme‐Smith, K., Vizthum, D., Lu, M., Agrawal, P. M., Urbina, E. M., & Brady, T. M. (2023) · Clinical Pediatrics · doi:10.1177/00099228231186666 · Cited by 7 · see citing works
Cohen, C. C., Dabelea, D., Michelotti, G. A., Tang, L., Shankar, K., Goran, M. I., & Perng, W. (2022) · Metabolites · doi:10.3390/metabo12060559 · Cited by 6 · see citing works
Cioffi, C. E., Welsh, J. A., Alvarez, J. A., Hartman, T. J., Narayan, K. M. V., & Vos, M. B. (2019) · Current Developments in Nutrition · doi:10.1093/cdn/nzz130 · Cited by 6 · see citing works
Triglycerides and Cardiovascular Disease : A Scientific Statement From the
Pennathur, S., Kris‐Etherton, P. M., Lennie, T. A., Levi, M., Mazzone, T., Ginsberg, H. N., Goldberg, A. C., Howard, W. J., Stone, N. J., Ballantyne, C. M., et al. (2011) · Cited by 6 · see citing works
Contributions of Prenatal Exposures and Child Lifestyle to Insulin Sensitivity
Alves, J. M., Zink, J., Chow, T., LUO, S. H., Belcher, B. R., Xiang, A. H., & Page, K. A. (2020) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/clinem/dgaa201 · Cited by 5 · see citing works
Harnois‐Leblanc, S., Rifas‐Shiman, S. L., Switkowski, K. M., Perng, W., Aris, I. M., Oken, E., Young, J. G., & Hivert, M. (2025) · American Journal of Epidemiology · doi:10.1093/aje/kwaf225 · Cited by 4 · see citing works
Overweight-obesity and cardiometabolic risk factors in adolescents from Merida city, Venezuela.
Rincón, Y., Paoli, M., Zerpa, Y., Briceño, Y., Gómez, R., Camacho, N. I., Martínez, J. L., & Valeri, L. (2015) · PubMed · Cited by 4 · see citing works
Changes in ideal cardiovascular health among Iranian adolescents: 2007–2008 to 2015–2017
Asghari, G., Mirmiran, P., Rezaeemanesh, A., Mahdavi, M., Azizi, F., & Hadaegh, F. (2022) · BMC Pediatrics · doi:10.1186/s12887-022-03504-x · Cited by 3 · see citing works
Ramaiyan, B., Zarei, M., Acharya, P., & Talahalli, R. R. (2020) · Journal of Food Science and Technology · doi:10.1007/s13197-020-04548-6 · Cited by 3 · see citing works
- Authors
- Bremer, A. A., Auinger, P., & Byrd, R. S.
- Affiliations
- University of California Davis Medical Center (US)
- University of Rochester (US)
- Venue
- Archives of Pediatrics & Adolescent Medicine
- Publisher
- American Medical Association (AMA)
- Published
- 2009-04-06
- Volume
- 163
- Issue
- 4
- Pages
- 328
- ISSN
- 1072-4710 (ISSN-L)
- PMC
- PMC4264593
- OpenAlex
- W2133450325
- Cited by
- 132
- References
- 58
- Citations by year
- 2025: 5 · 2024: 2 · 2023: 4 · 2022: 7 · 2021: 8 · 2020: 6 · 2019: 3 · 2018: 7 · 2017: 5 · 2016: 12 · 2015: 9 · 2014: 17 · 2013: 11 · 2012: 15
- FWCI
- 8.71
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Archives of Pediatrics and Adolescent Medicine (publishedVersion)
- PubMed (publishedVersion)
- Europe PMC (PubMed Central) (acceptedVersion)
- PubMed Central (acceptedVersion)
- Funders
- National Center for Research Resources (UL1RR024146, KL2RR024144)
- Topics
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diet, Metabolism, and Disease
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Obesity, Physical Activity, Diet
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes, Cardiovascular Risks, and Lipoproteins
- Keywords
- sugar-sweetened beverages, physical activity, insulin resistance, adolescents, HOMA-IR, anthropometry, body mass index, waist circumference, blood pressure, HDL cholesterol, LDL cholesterol, triglycerides, glucose and insulin, dietary change
- MeSH terms
- Adolescent, Age Factors, Anthropometry, Beverages, Blood Glucose, Child, Cross-Sectional Studies, Energy Metabolism, Female, Health Promotion, Humans, Insulin Resistance, Male, Motor Activity, Nutrition Surveys, Probability, Sex Factors, Sweetening Agents, United States, Body Mass Index, Multivariate Analysis, Linear Models, Young Adult
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
