Adiponectin Levels and Risk of Type 2 Diabetes: A Systematic Review and Meta-analysis

Bias in meta-analysis detected by a simple, graphical test

Egger, M., Smith, G. D., Schneider, M., & Minder, C. (1997) · BMJ · doi:10.1136/bmj.315.7109.629 · Cited by 56,722

Meta-analysis in clinical trials

DerSimonian, R., & Laird, N. (1986) · Controlled Clinical Trials · doi:10.1016/0197-2456(86)90046-2 · Cited by 39,552

Quantifying heterogeneity in a meta‐analysis

Higgins, J. P. T., & Thompson, S. G. (2002) · Statistics in Medicine · doi:10.1002/sim.1186 · Cited by 36,763

Meta-analysis of Observational Studies in Epidemiology<SUBTITLE>A Proposal for Reporting</SUBTITLE>

Stroup, D. F. (2000) · JAMA · doi:10.1001/jama.283.15.2008 · Cited by 20,623

Operating characteristics of a rank correlation test for publication bias

Begg, C. B., & Mazumdar, M. (1994) · Biometrics · doi:10.2307/2533446 · Cited by 16,955

Global and societal implications of the diabetes epidemic

Zimmet, P., Alberti, K. G. M. M., & Shaw, J. (2001) · Nature · doi:10.1038/414782a · Cited by 5,883

Hypoadiponectinemia in Obesity and Type 2 Diabetes: Close Association with Insulin Resistance and Hyperinsulinemia

Weyer, C., Funahashi, T., Tanaka, S., Hotta, K., Matsuzawa, Y., Pratley, R. E., & Tataranni, P. A. (2001) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.86.5.7463 · Cited by 3,541

Adiponectin and adiponectin receptors in insulin resistance, diabetes, and the metabolic syndrome

Kadowaki, T. (2006) · Journal of Clinical Investigation · doi:10.1172/jci29126 · Cited by 2,824

Methods for Trend Estimation from Summarized Dose-Response Data, with Applications to Meta-Analysis

Greenland, S., & Longnecker, M. P. (1992) · American Journal of Epidemiology · doi:10.1093/oxfordjournals.aje.a116237 · Cited by 2,353

Adipose tissue dysfunction in obesity, diabetes, and vascular diseases

Hajer, G. R., van Haeften, T. W., & Visseren, F. L. J. (2008) · European Heart Journal · doi:10.1093/eurheartj/ehn387 · Cited by 1,410

Adipokines in inflammation and metabolic disease

Ouchi, N., Parker, J. L., Lugus, J. J., & Walsh, K. (2011) · Nature Reviews Immunology · doi:10.1038/nri2921 · Cited by 4,625

Pathophysiology of human visceral obesity: an update

Tchernof, A., & Després, J.-P. (2013) · Physiological Reviews · doi:10.1152/physrev.00033.2011 · Cited by 2,583

Type 2 diabetes mellitus

DeFronzo, R. A., Ferrannini, E., Groop, L., Henry, R. R., Herman, W. H., Holst, J. J., Hu, F. B., Kahn, C. R., Raz, I., Shulman, G. I., et al. (2015) · Nature Reviews Disease Primers · doi:10.1038/nrdp.2015.19 · Cited by 2,611

Sex and Gender Differences in Risk, Pathophysiology and Complications of Type 2 Diabetes Mellitus

Kautzky-Willer, A., Harreiter, J., & Pacini, G. (2016) · Endocrine Reviews · doi:10.1210/er.2015-1137 · Cited by 2,043

Obesity and inflammation: the linking mechanism and the complications

Ellulu, M. S., Patimah, I., Khaza’ai, H., Rahmat, A., & Abed, Y. (2017) · Archives of Medical Science · doi:10.5114/aoms.2016.58928 · Cited by 1,982

Identification of serum metabolites associated with risk of type 2 diabetes using a targeted metabolomic approach

Floegel, A., Stefan, N., Yu, Z., Mühlenbruch, K., Drogan, D., Joost, H.-G., Fritsche, A., Häring, H.-U., Hrabě de Angelis, M., Peters, A., et al. (2013) · Diabetes · doi:10.2337/db12-0495 · Cited by 988

Trends in insulin resistance: insights into mechanisms and therapeutic strategy

Li, M., Chi, X., Wang, Y., Setrerrahmane, S., Xie, W., & Xu, H. (2022) · Signal Transduction and Targeted Therapy · doi:10.1038/s41392-022-01073-0 · Cited by 939

A small-molecule AdipoR agonist for type 2 diabetes and short life in obesity

Okada-Iwabu, M., Yamauchi, T., Iwabu, M., Honma, T., Hamagami, K.-I., Matsuda, K., Yamaguchi, M., Tanabe, H., Kimura-Someya, T., Shirouzu, M., et al. (2013) · Nature · doi:10.1038/nature12656 · Cited by 757

Risk factors for type 2 diabetes mellitus: An exposure-wide umbrella review of meta-analyses

Bellou, V., Belbasis, L., Tzoulaki, I., & Evangelou, E. (2018) · PLOS ONE · doi:10.1371/journal.pone.0194127 · Cited by 713

Adipocytokines in Obesity and Metabolic Disease

Cao, H. (2014) · Journal of Endocrinology · doi:10.1530/joe-13-0339 · Cited by 705

Adipokines Mediate Inflammation and Insulin Resistance

Kwon, H., & Pessin, J. E. (2013) · Frontiers in Endocrinology · doi:10.3389/fendo.2013.00071 · Cited by 723

The Role of Adiponectin in Cancer: A Review of Current Evidence

Dalamaga, Μ., Diakopoulos, K. N., & Mantzoros, C. S. (2012) · Endocrine Reviews · doi:10.1210/er.2011-1015 · Cited by 653

Curcumin Extract for Prevention of Type 2 Diabetes

Chuengsamarn, S., Rattanamongkolgul, S., Luechapudiporn, R., Phisalaphong, C., & Jirawatnotai, S. (2012) · Diabetes Care · doi:10.2337/dc12-0116 · Cited by 667

Adiponectin: mechanistic insights and clinical implications

Turer, A. T., & Scherer, P. E. (2012) · Diabetologia · doi:10.1007/s00125-012-2598-x · Cited by 650

Dietary pattern analysis and biomarkers of low-grade inflammation: a systematic literature review

Barbaresko, J., Koch, M., Schulze, M. B., & Nöthlings, U. (2013) · Nutrition Reviews · doi:10.1111/nure.12035 · Cited by 613

Insulin resistance and cancer risk: An overview of the pathogenetic mechanisms

Arcidiacono, B., Iiritano, S., Nocera, A., Possidente, K., Nevolo, M. T., Ventura, V., Foti, D., Chiefari, E., & Brunetti, A. (2012) · Experimental Diabetes Research · doi:10.1155/2012/789174 · Cited by 606

Adipokines: A link between obesity and cardiovascular disease

Nakamura, K., Fuster, J. J., & Walsh, K. X. (2013) · Journal of Cardiology · doi:10.1016/j.jjcc.2013.11.006 · Cited by 597

Whole grain and refined grain consumption and the risk of type 2 diabetes: a systematic review and dose–response meta-analysis of cohort studies

Aune, D., Norat, T., Romundstad, P., & Vatten, L. J. (2013) · European Journal of Epidemiology · doi:10.1007/s10654-013-9852-5 · Cited by 539

Estrogen: A master regulator of bioenergetic systems in the brain and body

Rettberg, J. R., Yao, J., & Brinton, R. D. (2014) · Frontiers in Neuroendocrinology · doi:10.1016/j.yfrne.2013.08.001 · Cited by 534

Novel Loci for Adiponectin Levels and Their Influence on Type 2 Diabetes and Metabolic Traits: A Multi-Ethnic Meta-Analysis of 45,891 Individuals

Dastani, Z., Hivert, M., Timpson, N. J., Perry, J. R. B., Yuan, X., Scott, R. A., Henneman, P., Heid, I. M., Kizer, J. R., Lyytikäinen, L., et al. (2012) · PLoS Genetics · doi:10.1371/journal.pgen.1002607 · Cited by 498

Adiponectin, TNF-α and Inflammatory Cytokines and Risk of Type 2 Diabetes: A Systematic Review and Meta-Analysis

Liu, C., Feng, X., Li, Q., Wang, Y., Li, Q., & Hua, M. (2016) · Cytokine · doi:10.1016/j.cyto.2016.06.028 · Cited by 470

Dietary fibre and incidence of type 2 diabetes in eight European countries: the EPIC-InterAct Study and a meta-analysis of prospective studies

The InterAct Consortium (2015) · Diabetologia · doi:10.1007/s00125-015-3585-9 · Cited by 476

The gut microbiota and its relationship to diet and obesity

Clarke, S. F., Murphy, E. F., Nilaweera, K. N., Ross, R. P., Shanahan, F., O’Toole, P. W., & Cotter, P. D. (2012) · Gut Microbes · doi:10.4161/gmic.20168 · Cited by 474

Stress hormones: physiological stress and regulation of metabolism

Kyrou, I., & Tsigos, C. (2009) · Current Opinion in Pharmacology · doi:10.1016/j.coph.2009.08.007 · Cited by 469

Epidemiologic relationship between periodontitis and type 2 diabetes mellitus

Wu, C., Yuan, Y., Liu, H.-H., Li, S.-S., Zhang, B., Chen, W., An, Z.-J., Chen, S., Wu, Y., Han, B., et al. (2020) · BMC Oral Health · doi:10.1186/s12903-020-01180-w · Cited by 432

Adiponectin in insulin resistance: lessons from translational research

Ziemke, F., & Mantzoros, C. S. (2009) · American Journal of Clinical Nutrition · doi:10.3945/ajcn.2009.28449c · Cited by 422

Molecular Events Linking Oxidative Stress and Inflammation to Insulin Resistance and β -Cell Dysfunction

Keane, K. N., Cruzat, V. F., Carlessi, R., de Bittencourt, P. I. H., & Newsholme, P. (2015) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2015/181643 · Cited by 401

Review: Diabetes, Obesity, and Cancer—Pathophysiology and Clinical Implications

Lega, I. C., & Lipscombe, L. L. (2019) · Endocrine Reviews · doi:10.1210/endrev/bnz014 · Cited by 381

Type 2-diabetes is associated with elevated levels of TNF-alpha, IL-6 and adiponectin and low levels of leptin in a population of Mexican Americans: A cross-sectional study

Mirza, S., Hossain, M., Mathews, C., Martinez, P., Pino, P., Gay, J. L., Rentfro, A., McCormick, J. B., & Fisher-Hoch, S. P. (2012) · Cytokine · doi:10.1016/j.cyto.2011.09.029 · Cited by 358

Environmental Obesogens: Mechanisms and Controversies

Heindel, J. J., & Blumberg, B. (2018) · The Annual Review of Pharmacology and Toxicology · doi:10.1146/annurev-pharmtox-010818-021304 · Cited by 354

Diabetes mellitus related bone metabolism and periodontal disease

Wu, Y., Xiao, E., & Graves, D. T. (2015) · International Journal of Oral Science · doi:10.1038/ijos.2015.2 · Cited by 318

Metabolic disruption in male mice due to fetal exposure to low but not high doses of bisphenol A (BPA): Evidence for effects on body weight, food intake, adipocytes, leptin, adiponectin, insulin and glucose regulation

Angle, B. M., Phuong, R., Ponzi, D., Stahlhut, R. W., Drury, B. E., Nagel, S. C., Welshons, W. V., Besch-Williford, C. L., Palanza, P., Parmigiani, S., et al. (2013) · Reproductive Toxicology · doi:10.1016/j.reprotox.2013.07.017 · Cited by 309

Risk assessment tools for identifying individuals at risk of developing type 2 diabetes

Buijsse, B., Simmons, R. K., Griffin, S. J., & Schulze, M. B. (2011) · Epidemiologic Reviews · doi:10.1093/epirev/mxq019 · Cited by 297

Reversal of Type 1 Diabetes in Mice by Brown Adipose Tissue Transplant

Gunawardana, S. C., & Piston, D. W. (2012) · Diabetes · doi:10.2337/db11-0510 · Cited by 290

The role of adiponectin in the pathogenesis and treatment of non‐alcoholic fatty liver disease

Pοlyzos, S. A., Kountouras, J., Zavos, C., & Tsiaousi, E. (2009) · Diabetes Obesity and Metabolism · doi:10.1111/j.1463-1326.2009.01176.x · Cited by 282

Depression and type 2 diabetes: Inflammatory mechanisms of a psychoneuroendocrine co-morbidity

Stuart, M. J., & Baune, B. T. (2012) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2011.10.001 · Cited by 257

Lactation and Progression to Type 2 Diabetes Mellitus After Gestational Diabetes Mellitus

Gunderson, E. P., Hurston, S. R., Ning, X., Lo, J. C.-M., Crites, Y., WALTON, D. L., Dewey, K. G., Azevedo, R. A., Young, S., Fox, G., et al. (2015) · Annals of Internal Medicine · doi:10.7326/m15-0807 · Cited by 262

Epidemiology of selenium and type 2 diabetes: Can we make sense of it?

Rayman, M. P., & Stranges, S. (2013) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2013.04.003 · Cited by 220

Prevention and control of type 2 diabetes by Mediterranean diet: A systematic review

Esposito, K., Maiorino, M. I., Ceriello, A., & Giugliano, D. (2010) · Diabetes Research and Clinical Practice · doi:10.1016/j.diabres.2010.04.019 · Cited by 208

Biomarkers for Insulin Resistance and Inflammation and the Risk for All-Cause Dementia and Alzheimer Disease

van Himbergen, T. M. (2012) · Archives of Neurology · doi:10.1001/archneurol.2011.670 · Cited by 202

Molecular and pathophysiological relationship between obesity and chronic inflammation in the manifestation of metabolic dysfunctions and their inflammation‑mediating treatment options (Review)

Varra, F., Varras, M. N., Varra, V., & Theodosis‐Nobelos, P. (2024) · Molecular Medicine Reports · doi:10.3892/mmr.2024.13219 · Cited by 232

ANIMAL MODELS OF DISEASE: Classification and etiology of diabetes in dogs and cats

Nelson, R. W., & Reusch, C. E. (2014) · Journal of Endocrinology · doi:10.1530/joe-14-0202 · Cited by 208

First-Trimester Prediction of Gestational Diabetes Mellitus: Examining the Potential of Combining Maternal Characteristics and Laboratory Measures

Savvidou, M. D., Nelson, S. M., Makgoba, M., Messow, C., Sattar, N. A., & Nicolaides, K. H. (2010) · Diabetes · doi:10.2337/db10-0688 · Cited by 181

Racial Differences in Cancer Susceptibility and Survival: More Than the Color of the Skin?

Özdemir, B. C., & Dotto, G. P. (2017) · Trends in cancer · doi:10.1016/j.trecan.2017.02.002 · Cited by 183

Effects of caffeinated and decaffeinated coffee on biological risk factors for type 2 diabetes: a randomized controlled trial

Wedick, N. M., Brennan, A., Sun, Q., Hu, F. B., Mantzoros, C. S., & van Dam, R. M. (2011) · Nutrition Journal · doi:10.1186/1475-2891-10-93 · Cited by 174

The diabetogenic action of statins — mechanisms and clinical implications

Betteridge, D. J., & Carmena, R. (2015) · Nature Reviews Endocrinology · doi:10.1038/nrendo.2015.194 · Cited by 176

Understanding the Physiological Links Between Physical Frailty and Cognitive Decline

Ma, L., & Chan, P. (2020) · Aging and Disease · doi:10.14336/ad.2019.0521 · Cited by 180

The Adiponectin Paradox for All-Cause and Cardiovascular Mortality

Menzaghi, C., & Trischitta, V. (2017) · Diabetes · doi:10.2337/dbi17-0016 · Cited by 172

Mediterranean Diet and Diabetes: Prevention and Treatment

Georgoulis, M., Kontogianni, M. D., & Yiannakouris, N. (2014) · Nutrients · doi:10.3390/nu6041406 · Cited by 185

Plasma Exosome MicroRNA Profiling Unravels a New Potential Modulator of Adiponectin Pathway in Diabetes: Effect of Glycemic Control

Santovito, D., Nardis, V. D., Marcantonio, P., Mandolini, C., Paganelli, C., Vitale, E., Buttitta, F., Bucci, M., Mezzetti, A., Consoli, A., et al. (2014) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2013-3843 · Cited by 172

Anti‐inflammatory cytokines and risk of type 2 diabetes

Herder, C., Carstensen, M., & Ouwens, D. M. (2013) · Diabetes Obesity and Metabolism · doi:10.1111/dom.12155 · Cited by 172

Obesity, adipokines and neuroinflammation

Aguilar‐Valles, A., Inoue, W., Rummel, C. D., & Luheshi, G. N. (2015) · Neuropharmacology · doi:10.1016/j.neuropharm.2014.12.023 · Cited by 173

Diabetic gut microbiota dysbiosis as an inflammaging and immunosenescence condition that fosters progression of retinopathy and nephropathy

Fernandes, R., Viana, S., Nunes, S., & Reis, F. (2018) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · doi:10.1016/j.bbadis.2018.09.032 · Cited by 171

Adipokines, Metabolic Syndrome and Rheumatic Diseases

Abella, V., Scotece, M., Conde, J., López, V., Lazzaro, V., Pino, J., Gómez-Reino, J. J., & Gualillo, O. (2014) · Journal of Immunology Research · doi:10.1155/2014/343746 · Cited by 160

Diabetes and inflammation: Fundamental aspects and clinical implications

Garcia, C., Fève, B., Ferré, P., Halimi, S., Baïzri, H., Bordier, L., Guiu, G., Dupuy, O., Bauduceau, B., & Mayaudon, H. (2010) · Diabetes & Metabolism · doi:10.1016/j.diabet.2010.07.001 · Cited by 167

Prediabetes and associated disorders

Buysschaert, M., Medina, J. L., Bergman, M., Shah, A., & Lonier, J. (2014) · Endocrine · doi:10.1007/s12020-014-0436-2 · Cited by 164

Clear detection of ADIPOQ locus as the major gene for plasma adiponectin: Results of genome-wide association analyses including 4659 European individuals

Heid, I. M., Henneman, P., Hicks, A. A., Coassin, S., Winkler, T. W., Aulchenko, Y. S., Fuchsberger, C., Song, K. S., Hivert, M., Waterworth, D. M., et al. (2009) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2009.11.035 · Cited by 159

Association between leptin, adiponectin and resistin and long-term progression of hand osteoarthritis

Yusuf, E., Ioan‐Facsinay, A., Bijsterbosch, J., Klein‐Wieringa, I. R., Kwekkeboom, J. C., Slagboom, P. E., Huizinga, T. W. J., & Kloppenburg, M. (2011) · Annals of the Rheumatic Diseases · doi:10.1136/ard.2010.146282 · Cited by 154

Adipose tissue depot and cell size dependency of adiponectin synthesis and secretion in human obesity

Meyer, L. K., Ciaraldi, T. P., Henry, R. R., Wittgrove, A. C., & Phillips, S. A. (2013) · Adipocyte · doi:10.4161/adip.24953 · Cited by 156

The role of obesity and adipose tissue dysfunction in osteoarthritis pain

Binvignat, M., Sellam, J., Berenbaum, F., & Felson, D. T. (2024) · Nature Reviews Rheumatology · doi:10.1038/s41584-024-01143-3 · Cited by 169

COMPANION ANIMALS SYMPOSIUM: Obesity in dogs and cats: What is wrong with being fat?1

Laflamme, D. P. (2011) · Journal of Animal Science · doi:10.2527/jas.2011-4571 · Cited by 152

Effect of adiponectin on bovine granulosa cell steroidogenesis, oocyte maturation and embryo development

Maillard, V., Uzbekova, S., Guignot, F., Perreau, C., Ramé, C., Coyral-Castel, S., & Dupont, J. (2010) · Reproductive Biology and Endocrinology · doi:10.1186/1477-7827-8-23 · Cited by 149

From inflammation to sexual dysfunctions: a journey through diabetes, obesity, and metabolic syndrome

Maiorino, M. I., Bellastella, G., Giugliano, D., & Esposito, K. (2018) · Journal of Endocrinological Investigation · doi:10.1007/s40618-018-0872-6 · Cited by 144

Effects of individual and combined dietary weight loss and exercise interventions in postmenopausal women on adiponectin and leptin levels

Abbenhardt, C., McTiernan, A., Alfano, C. M., Wener, M. H., Campbell, K. L., Duggan, C., Foster‐Schubert, K. E., Kong, A., Toriola, A. T., Potter, J. D., et al. (2013) · Journal of Internal Medicine · doi:10.1111/joim.12062 · Cited by 137

Whole grain consumption and human health: an umbrella review of observational studies

Tieri, M., Ghelfi, F., Vitale, M., Vetrani, C., Marventano, S., Lafranconi, A., Godos, J., Titta, L., Gambera, A., Alonzo, E., et al. (2020) · International Journal of Food Sciences and Nutrition · doi:10.1080/09637486.2020.1715354 · Cited by 151

The Vasculature in Prediabetes

Wasserman, D. H., Wang, T. J., & Brown, N. J. (2018) · Circulation Research · doi:10.1161/circresaha.118.311912 · Cited by 137

Inflammatory Concepts of Obesity

Rocha, V. Z., & Folco, E. J. E. (2011) · International Journal of Inflammation · doi:10.4061/2011/529061 · Cited by 140

Modulation of adiponectin as a potential therapeutic strategy

Lim, S. K., Quon, M. J., & Koh, K. K. (2014) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2014.01.051 · Cited by 140

Systematic review and meta-analysis of the associations of vegan and vegetarian diets with inflammatory biomarkers

Menzel, J., Jabakhanji, A., Biemann, R., Mai, K., Abraham, K., & Weikert, C. (2020) · Scientific Reports · doi:10.1038/s41598-020-78426-8 · Cited by 146

A Review on Oxidative Stress, Diabetic Complications, and the Roles of Honey Polyphenols

Pasupuleti, V. R., Arigela, C. S., Gan, S. H., Salam, S. K. N. M., Krishnan, K. T., Rahman, N. A., & Jeffree, M. S. (2020) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2020/8878172 · Cited by 148

Targeting metabolic disorders by natural products

Tabatabaei‐Malazy, O., Larijani, B. A., & Abdollahi, M. R. (2015) · Journal of Diabetes & Metabolic Disorders · doi:10.1186/s40200-015-0184-8 · Cited by 136

Fruit and vegetable consumption and risk of type 2 diabetes mellitus: A dose-response meta-analysis of prospective cohort studies

Wu, Y., Zhang, D., Jiang, X., & Jiang, W. (2014) · Nutrition Metabolism and Cardiovascular Diseases · doi:10.1016/j.numecd.2014.10.004 · Cited by 138

Exercise Increases Adiponectin and Reduces Leptin Levels in Prediabetic and Diabetic Individuals: Systematic Review and Meta-Analysis of Randomized Controlled Trials

Becic, T., Studenik, C., & Hoffmann, G. (2018) · Medical Sciences · doi:10.3390/medsci6040097 · Cited by 127

A Genome-Wide Association Study Reveals a Quantitative Trait Locus of Adiponectin on CDH13 That Predicts Cardiometabolic Outcomes

Chung, C., Lin, T., Chen, J., Leu, H., Yang, H., Ho, H., Ting, C.-T., Sheu, S., Tsai, W., Chen, J.-H., et al. (2011) · Diabetes · doi:10.2337/db10-1321 · Cited by 127

Adipose tissue mass and location affect circulating adiponectin levels

Turer, A. T., Khera, A., Ayers, C. R., Turer, C. B., Grundy, S. M., Vega, G. L., & Scherer, P. E. (2011) · Diabetologia · doi:10.1007/s00125-011-2252-z · Cited by 125

Adiponectin Induces Pro-inflammatory Programs in Human Macrophages and CD4+ T Cells

Cheng, X., Folco, E. J. E., Shimizu, K., & Libby, P. (2012) · Journal of Biological Chemistry · doi:10.1074/jbc.m112.409516 · Cited by 122

Obesity and Metabolic Syndrome: An Inflammatory Condition

Scarpellini, E., & Tack, J. F. (2012) · Digestive Diseases · doi:10.1159/000336664 · Cited by 124

Mendelian Randomization Studies Do Not Support a Causal Role for Reduced Circulating Adiponectin Levels in Insulin Resistance and Type 2 Diabetes

Yaghootkar, H., Lamina, C., Scott, R. A., Dastani, Z., Hivert, M., Warren, L. L., Stančáková, A., Buxbaum, S. G., Lyytikäinen, L., Henneman, P., et al. (2013) · Diabetes · doi:10.2337/db13-0128 · Cited by 121

Lower Adiponectin Levels at First Trimester of Pregnancy Are Associated With Increased Insulin Resistance and Higher Risk of Developing Gestational Diabetes Mellitus

Lacroix, M., Battista, M., Doyon, M., Ménard, J., Ardilouze, J., Perron, P., & Hivert, M. (2013) · Diabetes Care · doi:10.2337/dc12-1731 · Cited by 126

Adiponectin—Consideration for its Role in Skeletal Muscle Health

Krause, M. P., Milne, K. J., & Hawke, T. J. (2019) · International Journal of Molecular Sciences · doi:10.3390/ijms20071528 · Cited by 121

Systemic inflammation in childhood obesity: circulating inflammatory mediators and activated CD14++ monocytes

Schipper, H. S., Nuboer, R., Prop, S., van den Ham, H., de Boer, F. K., Keşmir, C., Mombers, I. M. H., van Bekkum, K. A., Woudstra, J., Kieft, J. H., et al. (2012) · Diabetologia · doi:10.1007/s00125-012-2641-y · Cited by 119

Association between adiponectin levels and coronary heart disease and mortality: a systematic review and meta-analysis

Lee, E. S., Park, S., Kim, E., Yoon, Y. S., Ahn, H. Y., Park, C., Yun, Y. H., & Oh, S. W. (2013) · International Journal of Epidemiology · doi:10.1093/ije/dyt087 · Cited by 121

Impaired Adiponectin Signaling Contributes to Disturbed Catabolism of Branched-Chain Amino Acids in Diabetic Mice

Lian, K., Du, C., Liu, Y., Zhu, D., Yan, W., Zhang, H., Hong, Z., Liu, P., Zhang, L., Pei, H., et al. (2014) · Diabetes · doi:10.2337/db14-0312 · Cited by 121

Adipokine Pattern in Subjects with Impaired Fasting Glucose and Impaired Glucose Tolerance in Comparison to Normal Glucose Tolerance and Diabetes

Tönjes, A., Faßhauer, M., Kratzsch, J., Stümvoll, M., & Blüher, M. (2010) · PLoS ONE · doi:10.1371/journal.pone.0013911 · Cited by 119

Hypoadiponectinemia—Cause or Consequence of Human “Insulin Resistance”?

Cook, J. R., & Semple, R. K. (2010) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2009-2286 · Cited by 119

Associations of a vegan diet with inflammatory biomarkers

Menzel, J., Biemann, R., Longree, A., Isermann, B., Mai, K., Schulze, M. B., Abraham, K., & Weikert, C. (2020) · Scientific Reports · doi:10.1038/s41598-020-58875-x · Cited by 126

Plasminogen activator inhibitor-1 and type 2 diabetes: a systematic review and meta-analysis of observational studies

Yarmolinsky, J., Barbieri, N. B., Weinmann, T., Ziegelmann, P. K., Duncan, B. B., & Schmidt, M. I. (2016) · Scientific Reports · doi:10.1038/srep17714 · Cited by 119

A Prospective Study of Plasma Adiponectin and Pancreatic Cancer Risk in Five US Cohorts

Bao, Y., Giovannucci, E. L., Kraft, P. L., Stampfer, M. J., Ogino, S., Ma, J., Buring, J. E., Sesso, H. D., Lee, I.-M. M., Gaziano, J. M., et al. (2012) · JNCI Journal of the National Cancer Institute · doi:10.1093/jnci/djs474 · Cited by 117

Hepatokines and adipokines in NASH-related hepatocellular carcinoma

Kücükoglu, Ö., Sowa, J., Mazzolini, G. D., Syn, W., & Canbay, A. E. (2020) · Journal of Hepatology · doi:10.1016/j.jhep.2020.10.030 · Cited by 114

Association of coffee consumption with serum adiponectin, leptin, inflammation and metabolic markers in Japanese workers: a cross-sectional study

Yamashita, K., Yatsuya, H., Muramatsu, T., Toyoshima, H., Murohara, T., & Tamakoshi, K. (2012) · Nutrition and Diabetes · doi:10.1038/nutd.2012.6 · Cited by 115

The role of the inflammatory microenvironment in thyroid carcinogenesis

Cunha, L. L., Marcello, M. A., & Ward, L. S. (2013) · Endocrine Related Cancer · doi:10.1530/erc-13-0431 · Cited by 114

Changes in insulin sensitivity precede changes in body composition during 14 days of step reduction combined with overfeeding in healthy young men

Knudsen, S. H., Hansen, L. S., Pedersen, M., Dejgaard, T., Hansen, J., Hall, G. V., Thomsen, C., Solomon, T. P. J., Pedersen, B. K., & Krogh-Madsen, R. (2012) · Journal of Applied Physiology · doi:10.1152/japplphysiol.00189.2011 · Cited by 112

Low adiponectin concentration during pregnancy predicts postpartum insulin resistance, beta cell dysfunction and fasting glycaemia

Retnakaran, R. R., Qi, Y., Connelly, P. W., Sermer, M., Hanley, A. J., & Zinman, B. (2009) · Diabetologia · doi:10.1007/s00125-009-1600-8 · Cited by 113

Accuracy of circulating adiponectin for predicting gestational diabetes: a systematic review and meta-analysis

Iliodromiti, S., Sassarini, J., Kelsey, T., Lindsay, R. S., Sattar, N. A., & Nelson, S. M. (2016) · Diabetologia · doi:10.1007/s00125-015-3855-6 · Cited by 116

Initial Dietary and Microbiological Environments Deviate in Normal‐weight Compared to Overweight Children at 10 Years of Age

Luoto, R., Kalliomäki, M. A., Laitinen, K., Delzenne, N. M., Cani, P. D., Salminen, S., & Isolauri, E. (2010) · Journal of Pediatric Gastroenterology and Nutrition · doi:10.1097/mpg.0b013e3181f3457f · Cited by 110

Adipose tissue changes in obesity and the impact on metabolic function

Sam, S., & Mazzone, T. (2014) · Translational research · doi:10.1016/j.trsl.2014.05.008 · Cited by 113

Mechanisms of obesity-induced metabolic and vascular dysfunctions

Caldwell, R. W. (2019) · Frontiers in bioscience · doi:10.2741/4758 · Cited by 112

Obesity and asthma: beyond TH2 inflammation

Leiria, L. O., Martins, M. A., & Saad, M. J. A. (2014) · Metabolism · doi:10.1016/j.metabol.2014.10.002 · Cited by 111

The role of adiponectin in human vascular physiology

Vaiopoulos, G., Marinou, K., Christodoulides, C., & Koutsilieris, M. (2011) · International Journal of Cardiology · doi:10.1016/j.ijcard.2011.07.047 · Cited by 108

Novel metabolic biomarkers of cardiovascular disease

Jensen, M. K., Bertoia, M. L., Cahill, L. E., Agarwal, I., Rimm, E. B., & Mukamal, K. J. (2014) · Nature Reviews Endocrinology · doi:10.1038/nrendo.2014.155 · Cited by 109

Adiponectin and protection against type 2 diabetes mellitus

Spranger, J., Kroke, A., Möhlig, M., Bergmann, M. M., Ristow, M., Boeing, H., & Pfeiffer, A. F. H. (2003) · The Lancet · doi:10.1016/s0140-6736(03)12255-6 · Cited by 1,120

Plasma adiponectin levels and type 2 diabetes risk: a nested case-control study in a Chinese population and an updated meta-analysis

Wang, Y., Meng, R., Kunutsor, S. K., Chowdhury, R., Yuan, J., Koh, W., & Pan, A. (2018) · Scientific Reports · doi:10.1038/s41598-017-18709-9 · Cited by 102

Association of Adiponectin Level and Type 2 Diabetes Mellitus (T2DM): A Systematic Review and Meta-Analysis

Nathan, D. S., & Yumilia, H. (2022) · International Journal For Research In Health Sciences And Nursing

Circulating adiponectin levels and risk of type 2 diabetes in the Japanese

Yamamoto, S., Matsushita, Y., Nakagawa, T., Hayashi, T., Noda, M., & Mizoue, T. (2014) · Nutrition and Diabetes · doi:10.1038/nutd.2014.27 · Cited by 80

Large sample case-control study of association between adiponectin and susceptibility to type 2 diabetes mellitus

Ling, Z. (2010) · Acta Universitatis Medicinalis Nanjing