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Trends in Smoking Among Adults With Mental Illness and Association Between Mental Health Treatment and Smoking Cessation
Open accessAbstract
IMPORTANCE: Significant progress has been made in reducing the prevalence of tobacco use in the United States. However, tobacco cessation efforts have focused on the general population rather than individuals with mental illness, who demonstrate greater rates of tobacco use and nicotine dependence. OBJECTIVES: To assess whether declines in tobacco use have been realized among individuals with mental illness and examine the association between mental health treatment and smoking cessation. DESIGN, SETTING, AND PARTICIPANTS: Use of nationally representative surveys of noninstitutionalized US residents to compare trends in smoking rates between adults with and without mental illness and across multiple disorders (2004-2011 Medical Expenditure Panel Survey [MEPS]) and to compare rates of smoking cessation among adults with mental illness who did and did not receive mental health treatment (2009-2011 National Survey of Drug Use and Health [NSDUH]).The MEPS sample included 32,156 respondents with mental illness (operationalized as reporting severe psychological distress, probable depression, or receiving treatment for mental illness) and 133,113 without mental illness. The NSDUH sample included 14,057 lifetime smokers with mental illness. MAIN OUTCOMES AND MEASURES: Current smoking status (primary analysis; MEPS sample) and smoking cessation, operationalized as a lifetime smoker who did not smoke in the last 30 days (secondary analysis; NSDUH sample). RESULTS: Adjusted smoking rates declined significantly among individuals without mental illness (19.2% [95% CI, 18.7-19.7%] to 16.5% [95% CI, 16.0%-17.0%]; P < .001) but changed only slightly among those with mental illness (25.3% [95% CI, 24.2%-26.3%] to 24.9% [95% CI, 23.8%- 26.0%]; P = .50), a significant difference in difference of 2.3% (95% CI, 0.7%-3.9%) (P = .005). Individuals with mental illness who received mental health treatment within the previous year were more likely to have quit smoking (37.2% [95% CI, 35.1%-39.4%]) than those not receiving treatment (33.1% [95% CI, 31.5%-34.7%]) (P = .005). CONCLUSIONS AND RELEVANCE: Between 2004 and 2011, the decline in smoking among individuals with mental illness was significantly less than among those without mental illness, although quit rates were greater among those receiving mental health treatment. This suggests that tobacco control policies and cessation interventions targeting the general population have not worked as effectively for persons with mental illness.
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“This is especially problematic for individuals with serious mental illness, who have the highest smoking rates and higher smoking severity 136 .”
From Substance use disorders: a comprehensive update of classification, epidemiology, neurobiology, clinical aspects, treatment and prevention (2023) · cites this paper as [136]
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“contribute to their low smoking cessation rates (Cook et al., 2014) and excess morbidity and mortality (Callaghan et al.”
BackgroundSocioeconomic Disparities in Smoking Among U.S. Adults With Depression, 2005–2014
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“Consistent with our data, the presence of depression has been linked to higher nicotine dependence, lower rates of quitting, greater difficulty with quitting and higher rates of relapse(20,21).”
BackgroundEvins, A. E., Hoeppner, S. S., Schoenfeld, D., Hoeppner, B. B., Cather, C., Pachas, G. N., Cieslak, K. M., & Maravić, M. C. (2016) · Schizophrenia Research · doi:10.1016/j.schres.2016.11.018 · Cited by 20
“2012) smoking rates are not declining among those with psychiatric illness (Cook et al. 2014).”
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Predictors of Tobacco Use Among New York State Addiction Treatment Patients
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“Behavioral health populations, especially, have not benefited from the overall population decline in smoking prevalence.(10) People with mental health diagnoses are twice as likely to smoke as those without,(11) and the highest prevalence rates reported are among people who seek treatment for alcohol or drug addiction.”
BackgroundUptake of smoking cessation aids by smokers with a mental illness
Metse, A. P., Wiggers, J. H., Wye, P. M., Clancy, R., Moore, L., Adams, M., Robinson, M., & Bowman, J. (2016) · Journal of Behavioral Medicine · doi:10.1007/s10865-016-9757-3 · Cited by 19
“Over the past two decades, the proportion of smokers in Australia (Australian Institute of Health and Welfare, 2011) and other high income countries (Cook et al., 2014; Office for National Statistics, 2014) has approximately halved.”
BackgroundMajor Depressive Disorder and Lifestyle: Correlated Genetic Effects in Extended Twin Pedigrees
Huider, F., Milaneschi, Y., van der Zee, M. D., de Geus, E. J. C., Helmer, Q., Penninx, B. W. J. H., & Boomsma, D. I. (2021) · Genes · doi:10.3390/genes12101509 · Cited by 19
“Epidemiological data show smoking rate to be increased in clinically depressed individuals at twice the rate of the general population [19,20], and both population-based studies as well as prospective cohort studies find elevated risk of MDD in those who smoke [21–23].”
ResultBhattacharya, A., Vilardaga, R., Kientz, J. A., & Munson, S. A. (2017) · CHI Conference on Human Factors in Computing Systems · doi:10.1145/3025453.3025725 · Cited by 21
“Individuals report different triggers for smoking and relapsing, experience different levels of difficulty with nicotine withdrawal, or may use smoking as a coping strategy for comorbid mental health conditions such as anxiety and depression [16,49].”
BackgroundBullen, C., Verbiest, M. E. A., Galea, S., Kurdziel, T., Laking, G. R., Newcombe, D. A. L., Parag, V., & Walker, N. K. (2018) · BMC Public Health · doi:10.1186/s12889-018-5351-7 · Cited by 18
“Although smokers with mental illnesses and/or AOD addictions are just as motivated as others to quit smoking [6] they are less likely to succeed [4, 7, 8].”
BackgroundJella, T. K., Cwalina, T. B., & Vallier, H. A. (2022) · Journal of Orthopaedic Trauma · doi:10.1097/bot.0000000000002433 · Cited by 17
Plooy, J.-L. D., Macharia, M., & Verster, C. (2016) · BMC Psychiatry · doi:10.1186/s12888-016-1123-z · Cited by 17
“Although global and South African prevalence of smoking has decreased in the general population as a result of anti-smoking regulations and extensive public campaigns [18–20], rates have declined much less, if at all, in people with mental disorders [21].”
BackgroundNair, U. S., Bell, M. L., Yuan, N. P., Wertheim, B. C., & Thomson, C. A. (2018) · Public Health Reports · doi:10.1177/0033354918764903 · Cited by 18
“among the general population,(4) smokers with such comorbid health conditions continue to have challenges to successful cessation.(8,9) Tobacco cessation quitlines are a pragmatic and costefficient strategy to deliver evidence-based cessation interventions.”
BackgroundManaging physical and mental health conditions: Consumer perspectives on integrated care
Rollins, A. L., Wright-Berryman, J., Henry, N. H., Quash, A. M., Benbow, K. L., Bonfils, K., Hedrick, H. M., Miller, A. P., Firmin, R., & Salyers, M. P. (2016) · Social Work in Mental Health · doi:10.1080/15332985.2016.1173160 · Cited by 17
“…sustained approaches targeted toward consumers with SMI, above and beyond interventions targeting the general population, to address smoking cessation (Cook et al., 2014; Evins et al., 2014; Schroeder & Morris, 2010) and weight reduction (Bartels & Desilets, 2012; Daumit et al., 2013).”
BackgroundPark, S. J., Wai, A., Pavithran, K., Kunheri, B., & Valsraj, K. M. (2021) · Psycho-Oncology · doi:10.1002/pon.5796 · Cited by 16
“poorer understanding of the effects to health, influence from peers, and habits picked up from time spent in psychiatric institutions.(25)”
BackgroundHigh prevalence of falsely declaring nicotine abstinence in lung transplant candidates
Veit, T., Munker, D., Leuschner, G., Mümmler, C., Sisic, A., Kauke, T., Schneider, C. P., Irlbeck, M., Michel, S. G., Eser-Valerie, D., et al. (2020) · PLoS ONE · doi:10.1371/journal.pone.0234808 · Cited by 16
“[21] Lung transplant candidates with a psychiatric and addictive history might benefit from targeted cessation intervention.”
BackgroundMarijuana Use and Adherence to Smoking Cessation Treatment Among Callers to Tobacco Quitlines
Carpenter, K., Torres, A. J., Salmon, E. E., Carlini, B. H., Vickerman, K. A., Schauer, G. L., & Bush, T. M. (2020) · Preventing Chronic Disease · doi:10.5888/pcd17.200110 · Cited by 16
Jaén‐Moreno, M. J., Feu, N., del Pozo, G. I., Gómez, C., Carrión, L., Chauca, G. M. C., Guler, I., Montiel, F. J., Sánchez, M. D., Alcalá, J. A., et al. (2021) · European Psychiatry · doi:10.1192/j.eurpsy.2021.12 · Cited by 17
Segan, C., Baker, A., Turner, A., & Williams, J. M. (2017) · Journal of Dual Diagnosis · doi:10.1080/15504263.2016.1276657 · Cited by 16
“…Smoking cessation; mental illness; nicotine withdrawal; medication side effects; quitline; telephone counseling Tobacco smoking rates are much higher in people living with mental illness compared to the general population, and are not showing the same rates of decline over time (Cook et al., 2014).”
BackgroundMalik, A. O., Peri-Okonny, P., GOSCH, K. L., Thomas, M. B., Mena‐Hurtado, C., Hiatt, W. R., Aronow, H. D., Jones, P. G., Provance, J., Labrosciano, C., et al. (2020) · Journal of Psychosomatic Research · doi:10.1016/j.jpsychores.2020.110313 · Cited by 19
“These include development of adverse health behaviors such as physical inactivity[34], obesity[27] and smoking[35].”
BackgroundFredman Stein, K., Sawyer, K., Daryan, S., Allen, J., & Taylor, G. (2023) · Health Expectations · doi:10.1111/hex.13684 · Cited by 11
Cruvinel, É., Liebmann, E. P., Leite, I. C. G., Hu, J., & Richter, K. P. (2020) · BMJ Open · doi:10.1136/bmjopen-2019-033959 · Cited by 15
Zyambo, C. M., Olowski, P., Mulenga, D., Syapiila, P., Liwewe, M. M., Ngoma-Hazemba, A., Halwiindi, H., & Siziya, S. (2023) · Asian Pacific Journal of Cancer Prevention · doi:10.31557/apjcp.2023.24.1.111 · Cited by 16
“We have further characterized the association of mental health problems and tobacco smoking (Cook et al., 2014; Zyambo et al., 2019), demonstrating that people who seriously considered suicide were twice more likely to smoke tobacco.”
BackgroundKang, J. X., Wu, J., Aggarwal, V. R., Shiers, D., Doran, T., & Palmier‐Claus, J. E. (2024) · Dentistry Journal · doi:10.3390/dj12070191 · Cited by 18
“There is strong evidence to suggest that people with SMI are more likely to smoke and smoke more heavily than the general population [12,33], and the findings provide evidence of its harmful effect on oral health, consistent with other studies [34,35].”
Schuck, R. K., Dahl, A., Hall, S. M., Delucchi, K., Fromont, S. C., Hall, S. E., Bonas, T., & Prochaska, J. J. (2014) · Tobacco Control · doi:10.1136/tobaccocontrol-2014-051712 · Cited by 18
Papadakis, S., Tulloch, H. E., Gharib, M., & Pipe, A. (2016) · CMAJ Open · doi:10.9778/cmajo.20150055 · Cited by 15
Yarborough, B. J. H., Stumbo, S. P., Cavese, J. A., Yarborough, M. T., & Green, C. A. (2018) · Patient Education and Counseling · doi:10.1016/j.pec.2018.08.036 · Cited by 14
Johnson, A. L., Kaye, J. T., Baker, T. B., Fiore, M. C., Cook, J. W., & Piper, M. E. (2019) · Drug and Alcohol Dependence · doi:10.1016/j.drugalcdep.2019.107796 · Cited by 17
McClellan, C. B., Maclean, J. C., Saloner, B. K., McGinty, E. E., & Pesko, M. F. (2020) · Health Economics · doi:10.1002/hec.4027 · Cited by 15
“…and poor health behaviors (e.g., smoking, diabetes, cardiovascular disease) and less likely to receive guideline-concordant care for behavioral and general health conditions than other insured populations (Busch et al., 2013, Creedon and Cook, 2016, Janssen et al., 2015, Cook et al., 2014).”
BackgroundType 2 Diabetes in Children and Adolescents on Atypical Antipsychotics
Pramyothin, P., & Khaodhiar, L. (2015) · Current Diabetes Reports · doi:10.1007/s11892-015-0623-4 · Cited by 16
Schuster, R. M., Cather, C., Pachas, G. N., Zhang, H., Cieslak, K. M., Hoeppner, S. S., Schoenfeld, D., & Evins, A. E. (2017) · Addictive Behaviors · doi:10.1016/j.addbeh.2017.02.028 · Cited by 15
“…disorder (Dickerson et al., 2013; Hartz et al., 2014; Kreinin et al., 2012), compared to 18% of the general U.S. population (Agaku et al., 2014; Le Cook et al., 2014; Address correspondence to Corinne Cather, PhD, MGH Center for Addiction Medicine, 60 Staniford Street Boston, MA 02114,…”
BackgroundImpact of Tobacco Quitlines on Smoking Cessation in Persons With Mental Illness: A Systematic Review
Schwindt, R. G., Hudmon, K. S., Knisely, M. R., Davis, L. L., & Pike, C. A. (2017) · Journal of Drug Education · doi:10.1177/0047237918762104 · Cited by 15
Yang, B. K., Spears, C. A., & Popova, L. (2018) · Addictive Behaviors · doi:10.1016/j.addbeh.2018.11.025 · Cited by 15
Song, F., Bachmann, M. O., Aveyard, P. N., Barton, G., Brown, T. J., Maskrey, V., Blyth, A., Notley, C. J., Holland, R., Sutton, S. R., et al. (2018) · PLoS ONE · doi:10.1371/journal.pone.0205992 · Cited by 15
Chavarria, J., Liu, M. A., Kast, L., Salem, E., & King, A. C. (2019) · Journal of Substance Abuse Treatment · doi:10.1016/j.jsat.2019.01.024 · Cited by 15
Spears, C., Jones, D. M., Weaver, S. R., Yang, B., Pechacek, T., & Eriksen, M. (2020) · Drug and Alcohol Dependence · doi:10.1016/j.drugalcdep.2020.108049 · Cited by 15
“population has been a public health success, tobacco control strategies have worked less well for people with MHC (Cook et al., 2014; Lawrence and Williams, 2016).”
BackgroundStrategies to deal with comorbid physical illness in psychosis
Docherty, M. J., Stubbs, B., & Gaughran, F. (2016) · Epidemiology and Psychiatric Sciences · doi:10.1017/s2045796016000056 · Cited by 16
“Whilst public health initiatives such as smoking cessation campaigns have been successful in driving down smoking rates in the general population, relatively little progress has been made among people with SMI with the smoking gap continuing to widen (Cook et al. 2014).”
BackgroundDaumit, G. L., Evins, A. E., Cather, C., Dalcin, A. T., Dickerson, F. B., Miller, E. R., Appel, L. J., Jerome, G. J., McCann, U., Ford, D. E., et al. (2023) · JAMA Psychiatry · doi:10.1001/jamapsychiatry.2023.1691 · Cited by 13
Routine screening of hospital patients for secondhand tobacco smoke exposure: A feasibility study
Kruse, G. R., & Rigotti, N. A. (2014) · Preventive Medicine · doi:10.1016/j.ypmed.2014.09.017 · Cited by 14
“The high rate of smoking among individuals with psychiatric diagnoses (Cook et al., 2014) may explain why nonsmokers with these diagnoses have a high rate of exposure to SHS.”
BackgroundBünnings, C. (2016) · Applied Economics · doi:10.1080/00036846.2016.1210766 · Cited by 14
“Hence, individuals who suffer from mental problems seem to have a considerably smaller probability to quit, which is consistent with findings by Lasser et al. (2000) and Leê Cook et al. (2014).”
ResultBeyraghi, N., Meybodi, A. M., & Bahri, R. J. (2018) · Psychiatry Journal · doi:10.1155/2018/2450939 · Cited by 14
Metadata
- Authors
- Cook, B. L., Wayne, G. F., Kafali, E. N., Liu, Z., Shu, C., & Flores, M.
- Affiliations
- Cambridge Health Alliance (US)
- Harvard Medical School/Cambridge Health Alliance, Department of Psychiatry, Cambridge, Massachusetts
- Southwest University (CN)
- Harvard University (US)
- Brown University (US)
- Venue
- JAMA
- Publisher
- American Medical Association (AMA)
- Published
- 2014-01-08
- Volume
- 311
- Issue
- 2
- Pages
- 172
- ISSN
- 0002-9955 (ISSN-L)
- 0098-7484
- PMC
- PMC5555156
- OpenAlex
- W2028087632
- Cited by
- 519
- References
- 46
- Citations by year
- 2026: 17 · 2025: 32 · 2024: 21 · 2023: 38 · 2022: 59 · 2021: 46 · 2020: 54 · 2019: 59 · 2018: 47 · 2017: 46 · 2016: 44 · 2015: 35 · 2014: 18
- FWCI
- 31.69
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- JAMA (publishedVersion)
- PubMed (publishedVersion)
- PubMed Central (acceptedVersion)
- Funders
- National Institutes of Health (5r01mh091042-02)
- National Institute on Aging (T32AG023482)
- National Institute of Mental Health (R01-MH091042)
- Topics
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Smoking Behavior and Cessation
- Health Sciences › Medicine › Epidemiology › Substance Abuse Treatment and Outcomes
- Health Sciences › Medicine › Psychiatry and Mental health › Mental Health Treatment and Access
- Keywords
- smoking, tobacco use, mental illness, smoking cessation, psychotherapy, nicotine dependence, tobacco use trends, depression, psychological distress, tobacco cessation interventions, tobacco control, adults with mental illness, tobacco harm reduction
- MeSH terms
- Adolescent, Adult, Aged, Mental Disorders, Female, Health Surveys, Humans, Male, Mental Health, Middle Aged, Smoking, Social Control, Formal, Tobacco Use Disorder, United States, Prevalence, Smoking Cessation, Young Adult
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