Cited by 124Nutritional Studies and DietDementia and Cognitive Impairment ResearchFatty Acid Research and Health

The DOI matches its Crossref record; 37 of the 38 references it cites were found in a registry or an index.

Association of Midlife Diet With Subsequent Risk for Dementia

Open access

Akbaraly, Tasnime N., Singh-Manoux, Archana, Dugravot, Aline, Brunner, Eric J., Kivimäki, Mika, Sabia, Séverine·2019·JAMA

DOI 10.1001/jama.2019.1432PMC PMC6436698

Open this paper in CoChat — free account

Abstract

Importance: Observational studies suggest that diet is linked to cognitive health. However, the duration of follow-up in many studies is not sufficient to take into account the long preclinical phase of dementia, and the evidence from interventional studies is not conclusive. Objective: To examine whether midlife diet is associated with subsequent risk for dementia. Design, Setting, and Participants: Population-based cohort study established in 1985-1988 that had dietary intake assessed in 1991-1993, 1997-1999, and 2002-2004 and follow-up for incident dementia until March 31, 2017. Exposures: Food frequency questionnaire to derive the Alternate Healthy Eating Index (AHEI), an 11-component diet quality score (score range, 0-110), with higher scores indicating a healthier diet. Main Outcome and Measures: Incident dementia ascertained through linkage to electronic health records. Results: Among 8225 participants without dementia in 1991-1993 (mean age, 50.2 years [SD, 6.1 years]; 5686 [69.1%] were men), a total of 344 cases of incident dementia were recorded during a median follow-up of 24.8 years (interquartile range, 24.2-25.1 years). No significant difference in the incidence rate for dementia was observed in tertiles of AHEI exposure during 1991-1993, 1997-1999 (median follow-up, 19.1 years), and 2002-2004 (median follow-up, 13.5 years). Compared with an incidence rate for dementia of 1.76 (95% CI, 1.47-2.12) per 1000 person-years in the worst tertile of AHEI (lowest tertile of diet quality) in 1991-1993, the absolute rate difference for the intermediate tertile was 0.03 (95% CI, -0.43 to 0.49) per 1000 person-years and for the best tertile was 0.04 (95% CI, -0.42 to 0.51) per 1000 person-years. Compared with the worst AHEI tertile in 1997-1999 (incidence rate for dementia, 2.06 [95% CI, 1.62 to 2.61] per 1000 person-years), the absolute rate difference for the intermediate AHEI tertile was 0.14 (95% CI, -0.58 to 0.86) per 1000 person-years and for the best AHEI tertile was 0.14 (95% CI, -0.58 to 0.85) per 1000 person-years. Compared with the worst AHEI tertile in 2002-2004 (incidence rate for dementia, 3.12 [95% CI, 2.49 to 3.92] per 1000 person-years), the absolute rate difference for the intermediate AHEI tertile was -0.61 (95% CI, -1.56 to 0.33) per 1000 person-years and for the best AHEI tertile was -0.73 (95% CI, -1.67 to 0.22) per 1000 person-years. In the multivariable analysis, the adjusted hazard ratios (HRs) for dementia per 1-SD (10-point) AHEI increment were not significant as assessed in 1991-1993 (adjusted HR, 0.97 [95% CI, 0.87 to 1.08]), in 1997-1999 (adjusted HR, 0.97 [95% CI, 0.83 to 1.12]), or in 2002-2004 (adjusted HR, 0.87 [95% CI, 0.75 to 1.00]). Conclusions and Relevance: In this long-term prospective cohort study, diet quality assessed during midlife was not significantly associated with subsequent risk for dementia.

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Integrity signals

Registry

Crossref · 10.1001/jama.2019.1432

Cites

37 of 37 references verified0 citation errors · 0 not checkable

Statistics

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Dementia prevention, intervention, and care
Livingston, G., Sommerlad, A., Orgeta, V., Costafreda, S. G., Huntley, J., Ames, D., Ballard, C., Banerjee, S., Burns, A., Cohen-Mansfield, J., et al. (2017) · The Lancet · doi:10.1016/s0140-6736(17)31363-6 · Cited by 6,072
Applied Longitudinal Analysis
Fitzmaurice, G. M., Laird, N. M., & Ware, J. H. (2011) · Wiley Series in Probability and Statistics · doi:10.1002/9781119513469 · Cited by 4,639
Tracking pathophysiological processes in Alzheimer's disease: an updated hypothetical model of dynamic biomarkers
Jack, C. R., Knopman, D. S., Jagust, W. J., Petersen, R. C., Weiner, M. W., Aisen, P. S., Shaw, L. M., Vemuri, P., Wiste, H. J., Weigand, S. D., et al. (2013) · The Lancet Neurology · doi:10.1016/s1474-4422(12)70291-0 · Cited by 4,396
Reproducibility and validity of a semiquantitative food frequency questionnaire
WILLETT, W. C., SAMPSON, L., STAMPFER, M. J., ROSNER, B., BAIN, C., WITSCHI, J., HENNEKENS, C. H., & SPEIZER, F. E. (1985) · American Journal of Epidemiology · doi:10.1093/oxfordjournals.aje.a114086 · Cited by 4,274
Dietary pattern analysis: a new direction in nutritional epidemiology
Hu, F. B. (2002) · Current Opinion in Lipidology · doi:10.1097/00041433-200202000-00002 · Cited by 4,029
Alternative Dietary Indices Both Strongly Predict Risk of Chronic Disease
Chiuve, S. E., Fung, T. T., Rimm, E. B., Hu, F. B., McCullough, M. L., Wang, M., Stampfer, M. J., & Willett, W. C. (2012) · The Journal of Nutrition · doi:10.3945/jn.111.157222 · Cited by 1,951
Defeating Alzheimer's disease and other dementias: a priority for European science and society
Winblad, B., Amouyel, P., Andrieu, S., Ballard, C., Brayne, C., Brodaty, H., Cedazo-Minguez, A., Dubois, B., Edvardsson, D., Feldman, H., et al. (2016) · The Lancet Neurology · doi:10.1016/s1474-4422(16)00062-4 · Cited by 1,676
Applied longitudinal analysis
(2004) · Choice Reviews Online · doi:10.5860/choice.42-2265 · Cited by 1,385
Brain foods: The effects of nutrients on brain function.
Gómez-Pinilla, F. (2008) · Nature Reviews Neuroscience · doi:10.1038/nrn2421 · Cited by 1,372
Word fluency and brain damage
Borkowski, J. G., Benton, A. L., & Spreen, O. (1967) · Neuropsychologia · doi:10.1016/0028-3932(67)90015-2 · Cited by 1,324

Show all 38 references

Research works printed but not linked: 1

Heim, 1970, AH 4 Group Test of General Intelligence ASE

Sorted by citations

Dementia prevention, intervention, and care: 2020 report of the Lancet Commission
Livingston, G., Huntley, J., Sommerlad, A., Ames, D., Ballard, C., Banerjee, S., Brayne, C., Burns, A., Cohen-Mansfield, J., Cooper, C., et al. (2020) · The Lancet · doi:10.1016/s0140-6736(20)30367-6 · Cited by 10,430
Retracted
Association of sleep duration in middle and old age with incidence of dementia
Sabia, S., Fayosse, A., Dumurgier, J., van Hees, V. T., Paquet, C., Sommerlad, A., Kivimäki, M., Dugravot, A., & Singh-Manoux, A. (2021) · Nature Communications · doi:10.1038/s41467-021-22354-2 · Cited by 628
Self-citation
Diet Quality as Assessed by the Healthy Eating Index, Alternate Healthy Eating Index, Dietary Approaches to Stop Hypertension Score, and Health Outcomes: A Second Update of a Systematic Review and Meta-Analysis of Cohort Studies
Morze, J., Danielewicz, A., HOFFMANN, G. E., & Schwingshackl, L. (2020) · Journal of the Academy of Nutrition and Dietetics · doi:10.1016/j.jand.2020.08.076 · Cited by 391
Modifiable Risk Factors for Alzheimer’s Disease
Edwards III, G. A., Gamez, N., Escobedo Jr., G., Calderon, O., & Moreno-Gonzalez, I. (2019) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2019.00146 · Cited by 253
Promoting Successful Cognitive Aging: A Ten-Year Update
Krivanek, T. J., Gale, S. A., McFeeley, B. M., Nicastri, C. M., & Daffner, K. R. (2021) · Journal of Alzheimer s Disease · doi:10.3233/jad-201462 · Cited by 189
Association of the Mediterranean Dietary Approaches to Stop Hypertension Intervention for Neurodegenerative Delay (MIND) Diet With the Risk of Dementia
Chen, H., Dhana, K., Huang, Y., Huang, L., Tao, Y., Liu, X., Melo van Lent, D., Zheng, Y., Ascherio, A., Willett, W., et al. (2023) · JAMA Psychiatry · doi:10.1001/jamapsychiatry.2023.0800 · Cited by 170
Mediterranean diet adherence is associated with lower dementia risk, independent of genetic predisposition: findings from the UK Biobank prospective cohort study
Shannon, O. M., Ranson, J. M., Gregory, S., Macpherson, H., Milte, C., Lentjes, M., Mulligan, A., McEvoy, C., Griffiths, A., Matu, J., et al. (2023) · BMC Medicine · doi:10.1186/s12916-023-02772-3 · Cited by 167
Nutrition state of science and dementia prevention: recommendations of the Nutrition for Dementia Prevention Working Group
Yassine, H. N., Samieri, C., Livingston, G., Glass, K., Wagner, M., Tangney, C., Plassman, B. L., Ikram, M. A., Voigt, R. M., Gu, Y., et al. (2022) · The Lancet Healthy Longevity · doi:10.1016/s2666-7568(22)00120-9 · Cited by 116
Alzheimer’s Disease: Etiology, Neuropathology and Pathogenesis
Sheppard, O., & Coleman, M. P. (2020) · Exon Publications eBooks · doi:10.36255/exonpublications.alzheimersdisease.2020.ch1 · Cited by 127
Healthy dietary patterns and the risk of individual chronic diseases in community-dwelling adults
Shang, X., Liu, J., Zhu, Z., Zhang, X., Huang, Y., Liu, S., Wang, W., Zhang, X., Tang, S., Hu, Y., et al. (2023) · Nature Communications · doi:10.1038/s41467-023-42523-9 · Cited by 111
MIND diet and the risk of dementia: a population-based study
de Crom, T. O. E., Mooldijk, S. S., Ikram, M. K., Ikram, M. A., & Voortman, T. (2022) · Alzheimer s Research & Therapy · doi:10.1186/s13195-022-00957-1 · Cited by 105
Dietary pattern, diet quality, and dementia: a systematic review and meta-analysis of prospective cohort studies
Liu, Y.-H., Gao, X., Na, M., Kris-Etherton, P. M., Mitchell, D. C., & Jensen, G. L. (2020) · Journal of Alzheimer's Disease · doi:10.3233/jad-200499 · Cited by 86
Association of social isolation, loneliness and genetic risk with incidence of dementia: UK Biobank Cohort Study
Elovainio, M., Lahti, J., Pirinen, M., Pulkki-Råback, L., Malmberg, A., Lipsanen, J., Virtanen, M., Kivimäki, M., & Hakulinen, C. (2022) · BMJ Open · doi:10.1136/bmjopen-2021-053936 · Cited by 85
Vascular cognitive impairment – Past, present, and future challenges
Badji, A., Youwakim, J., Cooper, A., Westman, E., & Marseglia, A. (2023) · Ageing Research Reviews · doi:10.1016/j.arr.2023.102042 · Cited by 84
Association between dietary diversity and cognitive impairment among the oldest-old: Findings from a nationwide cohort study
Zheng, J., Zhou, R., Li, F., Chen, L., Wu, K., Huang, J., Liu, H., Huang, Z., Xu, L., Yuan, Z., et al. (2021) · Clinical Nutrition · doi:10.1016/j.clnu.2021.02.041 · Cited by 77
Can nutrition support healthy cognitive ageing and reduce dementia risk?
Jennings, A., Cunnane, S. C., & Minihane, A. M. (2020) · BMJ · doi:10.1136/bmj.m2269 · Cited by 69
Whole dietary patterns, cognitive decline and cognitive disorders: a systematic review of prospective and intervention studies
Townsend, R. F., Logan, D., O’Neill, R. F., Prinelli, F., Woodside, J. V., & McEvoy, C. T. (2023) · Nutrients · doi:10.3390/nu15020333 · Cited by 59
Dietary patterns are related to cognitive functioning in elderly enriched with individuals at increased risk for Alzheimer’s disease
Wesselman, L. M. P., van Lent, D. M., Schröder, A., van de Rest, O., Peters, O., Menne, F., Fuentes, M., Priller, J., Spruth, E. J., Altenstein, S., et al. (2020) · European Journal of Nutrition · doi:10.1007/s00394-020-02257-6 · Cited by 66
The Role of Natural Antioxidants in the Prevention of Dementia—Where Do We Stand and Future Perspectives
Jurcău, A. (2021) · Nutrients · doi:10.3390/nu13020282 · Cited by 54
Associations of socioeconomic status and healthy lifestyle with incident dementia and cognitive decline: two prospective cohort studies
Wang, K., Fang, Y., Zheng, R., Zhao, X., Wang, S., Lu, J., Wang, W., Ning, G., Xu, Y., & Bi, Y. (2024) · EClinicalMedicine · doi:10.1016/j.eclinm.2024.102831 · Cited by 56
The age-performance relationship in the general population and strategies to delay age related decline in performance
Berthelot, G., Johnson, S., Noirez, P., Antero, J., Marck, A., Desgorces, F.-D., Pifferi, F., Carter, P. A., Spedding, M., Singh‐Manoux, A., et al. (2019) · Archives of Public Health · doi:10.1186/s13690-019-0375-8 · Cited by 57
Self-citation
Plant‐based dietary patterns and cognitive function: A prospective cohort analysis of elderly individuals in China (2008–2018)
Zhu, A., Yuan, C., Pretty, J., & Ji, J. S. (2022) · Brain and Behavior · doi:10.1002/brb3.2670 · Cited by 48
Long-Term Trajectories of Body Weight, Diet, and Physical Activity From Midlife Through Late Life and Subsequent Cognitive Decline in Women
Wagner, M., Grodstein, F., Proust‐Lima, C., & Samieri, C. (2019) · American Journal of Epidemiology · doi:10.1093/aje/kwz262 · Cited by 51
Associations of Midlife Dietary Patterns with Incident Dementia and Brain Structure: Findings from the UK Biobank Study
Zhang, J., Cao, X., Li, X., Li, X., Sun, X., Xia, Y., Hao, M., Sun, C., Xia, Y., Huang, H., et al. (2023) · American Journal of Clinical Nutrition · doi:10.1016/j.ajcnut.2023.05.007 · Cited by 43
Dietary patterns in middle age: effects on concurrent neurocognition and risk of age-related cognitive decline
Gauci, S., Young, L. M., Arnoldy, L., Lassemillante, A. M., Scholey, A. B., & Pipingas, A. (2021) · Nutrition Reviews · doi:10.1093/nutrit/nuab047 · Cited by 46
Adherence to Dietary Patterns and Risk of Incident Dementia: Findings from the Atherosclerosis Risk in Communities Study
Hu, E. A., Wu, A., Dearborn, J. L., Gottesman, R. F., Sharrett, A. R., Steffen, L. M., Coresh, J., & Rebholz, C. M. (2020) · Journal of Alzheimer s Disease · doi:10.3233/jad-200392 · Cited by 43
Association Between Dietary Habits in Midlife With Dementia Incidence Over a 20-Year Period
Glans, I., Sonestedt, E., Nägga, K., Gustavsson, A.-M., González-Padilla, E., Borne, Y., Stomrud, E., Melander, O., Nilsson, P. M., Palmqvist, S., et al. (2023) · Neurology · doi:10.1212/wnl.0000000000201336 · Cited by 40
Association of Dietary Patterns in Midlife and Cognitive Function in Later Life in US Adults Without Dementia
Dearborn, J. L., Wu, A., Steffen, L. M., Anderson, C. A. M., Hu, E. A., Knopman, D. S., Mosley, T. H., & Gottesman, R. F. (2019) · JAMA Network Open · doi:10.1001/jamanetworkopen.2019.16641 · Cited by 41
Which components of the Mediterranean diet are associated with dementia? A UK Biobank cohort study
Dobreva, I., Marston, L., & Mukadam, N. (2022) · GeroScience · doi:10.1007/s11357-022-00615-2 · Cited by 38
Associations of the Mediterranean‐DASH Intervention for Neurodegenerative Delay diet with brain structural markers and their changes
Chen, H., Dunk, M. M., Wang, B., Zhao, M., Shen, J., Zong, G., Pan, Y., Tong, L., Xu, W., & Yuan, C. (2023) · Alzheimer s & Dementia · doi:10.1002/alz.13521 · Cited by 36
The role of glucose in cognition, risk of dementia, and related biomarkers in individuals without type 2 diabetes mellitus or the metabolic syndrome: A systematic review of observational studies
Kirvalidze, M., Hodkinson, A., Storman, D., Fairchild, T. J., Bała, M. M., Beridze, G., Zuriaga, A., Brudasca, N. I., & Brini, S. (2022) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2022.104551 · Cited by 38
The Effect of Healthy Diet on Cognitive Performance Among Healthy Seniors – A Mini Review
Klímová, B., Dziuba, S. T., & Cierniak–Emerych, A. (2020) · Frontiers in Human Neuroscience · doi:10.3389/fnhum.2020.00325 · Cited by 34
Sleep disorders and risk of alzheimer's disease: A two-way road
Lacerda, R. A. V., Desio, J. A. F., Kammers, C. M., Henkes, S. F. C., de Sá, M. F., de Souza, E. F., da Silva, D. M., Gusmão, C. T. P., & dos Santos, J. C. C. (2024) · Ageing Research Reviews · doi:10.1016/j.arr.2024.102514 · Cited by 36
Dietary Pattern Trajectories in Middle Age and Physical Function in Older Age
Talegawkar, S. A., Jin, Y., Xue, Q., Tanaka, T., Simonsick, E. M., Tucker, K. L., & Ferrucci, L. (2020) · The Journals of Gerontology Series A · doi:10.1093/gerona/glaa287 · Cited by 32
Alternate Healthy Eating Index is Positively Associated with Cognitive Function Among Middle-Aged and Older Hispanics/Latinos in the HCHS/SOL
Estrella, M. L., Durazo-Arvizú, R., Mattei, J., Mossavar‐Rahmani, Y., Perreira, K. M., Siega‐Riz, A. M., Sotres‐Alvarez, D., González, H. M., Gallo, L. C., Daviglus, M. L., et al. (2020) · Journal of Nutrition · doi:10.1093/jn/nxaa023 · Cited by 28
Sugary beverages and genetic risk in relation to brain structure and incident dementia: a prospective cohort study
Chen, H., Chen, J., Cao, Y., Sun, Y., Huang, L., Ji, J. S., Voortman, T., Vernooij, M. W., Shen, J., Zheng, Y., et al. (2023) · American Journal of Clinical Nutrition · doi:10.1016/j.ajcnut.2023.01.015 · Cited by 29
The intricate interplay between dietary habits and cognitive function: insights from the gut-brain axis
Zhang, R., Zhang, M., & Wang, P. (2025) · Frontiers in Nutrition · doi:10.3389/fnut.2025.1539355 · Cited by 31
Ultra-processed food consumption and risk of dementia and Alzheimer's disease: The Framingham Heart Study
Weinstein, G., Kojis, D. J., Banerjee, A., Seshadri, S. S., Walker, M. E., & Beiser, A. (2025) · The Journal of Prevention of Alzheimer s Disease · doi:10.1016/j.tjpad.2024.100042 · Cited by 24
Brain Age Difference at Baseline Predicts Clinical Dementia Rating Change in Approximately Two Years
Tseng, W.-Y. I., Hsu, Y.-C., & Kao, T.-W. (2022) · Journal of Alzheimer s Disease · doi:10.3233/jad-215380 · Cited by 22
Nutrition and Metabolic Profiles in the Natural History of Dementia: Recent Insights from Systems Biology and Life Course Epidemiology
Lefèvre‐Arbogast, S., Wagner, M., Proust‐Lima, C., & Samieri, C. (2019) · Current Nutrition Reports · doi:10.1007/s13668-019-00285-1 · Cited by 22
Associations of Dietary Pattern and Sleep Duration with Cognitive Decline in Community-Dwelling Older Adults: A Seven-Year Follow-Up Cohort Study
Shang, X., Hodge, A. M., Hill, E., Zhu, Z., & He, M. (2021) · Journal of Alzheimer s Disease · doi:10.3233/jad-201329 · Cited by 22
Dietary Patterns and Brain Health in Middle-Aged and Older Adults: A Narrative Review
Seabrook, J. A., Avan, A., O’Connor, C. P., Harry Prapavessis, A., Nagamatsu, L. S., Twynstra, J., Stranges, S., MacDougall, A. G., & Hachinski, V. (2025) · Nutrients · doi:10.3390/nu17091436 · Cited by 17
The interactive effects of psychosocial stress and diet composition on health in primates
Shively, C. A., Frye, B. M., Negrey, J. D., Johnson, C. S. C., Sutphen, C. L., Molina, A. J. A., Yadav, H., Snyder‐Mackler, N., & Register, T. C. (2023) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2023.105320 · Cited by 17
Identification of immune cells infiltrating in hippocampus and key genes associated with Alzheimer’s disease
Liu, C., Xu, S., Liu, Q., Chai, H., Luo, Y., & Li, S. (2023) · BMC Medical Genomics · doi:10.1186/s12920-023-01458-2 · Cited by 18
Midlife obesity, related behavioral factors, and the risk of dementia in later life
Beydoun, M. A., & Mika Kivimaki, B. (2019) · Neurology · doi:10.1212/wnl.0000000000008775 · Cited by 16
Associations of Diet Quality with Midlife Brain Volume: Findings from the UK Biobank Cohort Study
Macpherson, H., McNaughton, S. A., Lamb, K. E., & Milte, C. M. (2021) · Journal of Alzheimer s Disease · doi:10.3233/jad-210705 · Cited by 16
Racial and ethnic minority representation in dementia risk factor research: a scoping review of cohort studies
Krishnan, A., Pathak, A., Nicholas, T. B., Lee, J., Waite, L. M., & Stanaway, F. (2024) · BMJ Open · doi:10.1136/bmjopen-2024-085592 · Cited by 14
Impact of metabolic dysfunction on cognition in humans
Rasmussen, I. J., Thomassen, J. Q., & Frikke‐Schmidt, R. (2020) · Current Opinion in Lipidology · doi:10.1097/mol.0000000000000723 · Cited by 14
Adherence to dietary guidelines and risk of dementia: a prospective cohort study of 94 184 individuals
Kjeldsen, E. W., Thomassen, J. Q., Rasmussen, K. L., Nordestgaard, B. G., Tybjærg-Hansen, A., & Frikke-Schmidt, R. (2022) · Epidemiology and Psychiatric Sciences · doi:10.1017/s2045796022000567 · Cited by 13
Dietary Patterns and Indicators of Cognitive Function
Chen, H., Cortese, M., Flores‐Torres, M. H., Tessier, A., Wang, D. D., Kang, J. H., Eliassen, A. H., Stampfer, M. J., Ascherio, A., Willett, W. C., et al. (2026) · JAMA Neurology · doi:10.1001/jamaneurol.2026.0062 · Cited by 13
Reliability and reproducibility of systematic reviews informing the 2020–2025 Dietary Guidelines for Americans: a pilot study
Bodnaruc, A. M., Khan, H., Shaver, N., Bennett, A., Wong, Y. L., Gracey, C., Ly, V., Shea, B., Little, J., Brouwers, M. C., et al. (2024) · American Journal of Clinical Nutrition · doi:10.1016/j.ajcnut.2024.10.013 · Cited by 16
Prospective Study of Diet Quality and the Risk of Dementia in the Oldest Old
Flores, A. C., Jensen, G. L., Mitchell, D. C., Na, M., Wood, G. C., Still, C. D., & Gao, X. (2023) · Nutrients · doi:10.3390/nu15051282 · Cited by 10
Association of diet quality during pregnancy with maternal glucose metabolism in Chinese women
Pan, W., Karatela, S., Lu, Q., Xie, L., Wu, S., Jing, J., & Cai, L. (2023) · British Journal of Nutrition · doi:10.1017/s0007114523000107 · Cited by 9
Patterns of lifestyle behaviours from mid- through later-life in relation to exceptional episodic memory performance in older women: the Nurses’ Health Study
Wagner, M., & Grodstein, F. (2022) · Age and Ageing · doi:10.1093/ageing/afac102 · Cited by 12
Healthcare Complexities in Neurodegenerative Proteinopathies: A Narrative Review
Fereshtehnejad, S., & Lökk, J. (2025) · Healthcare · doi:10.3390/healthcare13151873 · Cited by 11
Dietary intake is associated with neuropsychological impairment in women with HIV
Rubin, L. H., Gustafson, D., Warrior, L., Sheira, L. A., Fitzgerald, K. C., Dastgheyb, R. M., Weber, K. M., Tien, P. C., French, A. L., Spence, A. B., et al. (2021) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/nqab038 · Cited by 8
Diet patterns and cognitive performance in a UK Female Twin Registry (TwinsUK)
McEvoy, C. T., Jennings, A., Steves, C. J., MacGregor, A. J., Spector, T. D., & Cassidy, A. (2024) · Alzheimer s Research & Therapy · doi:10.1186/s13195-024-01387-x · Cited by 9
Lifestyle Interventions and Innovative Approaches for the Management of Neurodegenerative Disorders in Older Adults—State-Of-The-Art and Future Directions
Popescu, I. R., Lenain, M., Rovini, E., & Ruthsatz, M. (2025) · American Journal of Lifestyle Medicine · doi:10.1177/15598276251330170 · Cited by 7
Dietary Factors and Cognitive Function: with a Focus on Subjective Cognitive Decline
Yeh, T., Blacker, D., & Willett, W. C. (2025) · Current Nutrition Reports · doi:10.1007/s13668-025-00638-z · Cited by 8
Impact of Diverse Dietary Patterns on Cognitive Health: Cumulative Evidence from Prospective Cohort Studies
Kim, Y., Je, M., Kang, K., & Kim, Y. (2025) · Nutrients · doi:10.3390/nu17213469 · Cited by 7
The interaction effect of metals exposure and dietary habit on cognitive function in Chinese older adult cohort
Liu, P., Wang, J., Mei, P., Li, J., Xu, B., Ren, X., Chen, X., Wu, D., Zhu, F., Yang, X., et al. (2024) · The journal of nutrition health & aging · doi:10.1016/j.jnha.2024.100284 · Cited by 7
Exploring the Involvement of the Amyloid Precursor Protein A673T Mutation against Amyloid Pathology and Alzheimer’s Disease in Relation to Therapeutic Editing Tools
Stanciu, G. D., Ababei, D. C., Rusu, R.-N., Bild, V., & Tamba, B.-I. (2022) · Pharmaceutics · doi:10.3390/pharmaceutics14061270 · Cited by 6
The Relationship Between Dietary Patterns, Cognition, and Cardiometabolic Health in Healthy, Older Adults
Simpson, F. M., Wade, A. T., Stanford, T., Mellow, M. L., Collins, C. E., Murphy, K. J., Keage, H. A. D., Hunter, M., Ware, N., Barker, D., et al. (2024) · Nutrients · doi:10.3390/nu16223890 · Cited by 6
Mediterranean-Dietary Approaches to Stop Hypertension Intervention for Neurodegeneration Delay (MIND) Diet, Circulating Inflammatory Biomarkers, and Cognitive Function: A Prospective Study
Fei, L., Chen, H., Zhao, M., Wu, M., Lin, Q., Shen, T., Tong, L., Xu, X., Liu, X., Mi, B., et al. (2025) · Journal of Nutrition · doi:10.1016/j.tjnut.2025.08.018 · Cited by 5
Association between plant-based diets and incident dementia: results from prospective cohort studies and a meta-analysis
Shen, J., Chen, H., Gong, Y., Huang, Y., Wu, M., Gu, Y., Wang, T., Fontana, L., Rong, S., Qian, S., et al. (2026) · The Journal of Prevention of Alzheimer s Disease · doi:10.1016/j.tjpad.2025.100457 · Cited by 5
Neighbourhood Urban Environments and Cognitive Health in Ageing Populations
Soloveva, M. V., Poudel, G. R., Barnett, A. H., & Cerin, E. (2024) · Springer eBooks · doi:10.1007/978-3-031-64699-7_13 · Cited by 5
Dietary factors and Alzheimer’s disease risk: a Mendelian randomization study
Meng, Q., Chen, C., Zhu, M., & Huang, Y. (2024) · European journal of medical research · doi:10.1186/s40001-024-01821-8 · Cited by 6
Postnatal exposure to lipopolysaccharide combined with high-fat diet consumption induces immune tolerance without prevention in spatial working memory impairment
Vargas-Rodríguez, I., Reyes‐Castro, L. A., Pacheco‐López, G., Lomas‐Soria, C., Zambrano, E., Dı́az-Ruiz, A., & Díaz-Cintra, S. Y. (2022) · Behavioural Brain Research · doi:10.1016/j.bbr.2022.113776 · Cited by 5
Association of Combined Healthy Lifestyle Factors With Incident Dementia in Participants With and Without Multimorbidity: A Large Population-Based Prospective Cohort Study
Niu, Y., Zhong, J.-F., Wen, H.-Y., Yan, H., Diao, Z., Li, J., Bai, X., Qiu, J., Xu, Z. N., Chen, L., et al. (2024) · The Journals of Gerontology Series A · doi:10.1093/gerona/glae034 · Cited by 5
Resistance and Resilience to Alzheimer's DiseasePreprint
Latimer, C. S., Prater, K. E., Postupna, N. O., & Keene, C. D. (2023) · Cold Spring Harbor Perspectives in Medicine · doi:10.1101/cshperspect.a041201 · Cited by 8
The Implications of Dietary Habits for Dementia
Peters, N., & Nacmias, B. (2022) · Neurology · doi:10.1212/wnl.0000000000201420 · Cited by 4
Association Between Dietary Patterns and Cognitive Function in Midlife Adults: The Bogalusa Heart Study
Ogarrio, K., Santos, M. P., Anda‐Duran, I. D., Potts, K. S., Bazzano, L., & Ley, S. H. (2025) · Nutrients · doi:10.3390/nu17101636 · Cited by 3
Diet Quality and Dementia Risk in Older Adults With Alzheimer Pathology
Mrhar, A., Carballo‐Casla, A., Grande, G., Gregorio, C., Triolo, F., Valletta, M., Fredolini, C., Kramberger, M. G., Kuhar, A., Winblad, B., et al. (2026) · JAMA Network Open · doi:10.1001/jamanetworkopen.2026.20254 · Cited by 3
The potential of circulating nonesterified fatty acids and sphingolipids in the biological understanding of cognitive decline and dementia
Moseholm, K. F., Meineche, J. T., & Jensen, M. K. (2024) · Current Opinion in Lipidology · doi:10.1097/mol.0000000000000968 · Cited by 3
Dietary Patterns and Neurocognitive Health: A Systematic Review
Boushey, C. J., Ard, J. D., Bazzano, L., Heymsfield, S. B., Mayer‐Davis, E. J., Sabaté, J., Snetselaar, L. G., Horn, L. V., Schneeman, B. O., English, L., et al. (2020) · doi:10.52570/nesr.dgac2020.sr0106 · Cited by 3
Improvement of cognitive performance by a nutraceutical formulation: Underlying mechanisms revealed by laboratory studies
Shea, T. B. (2021) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2021.07.039 · Cited by 3
Cetoleic acid and other long-chain unsaturated fatty acids as neuroprotective nutraceuticals
Tang, P., Ruiz-Pastor, M. J., Lewis, A. E., Fladmark, K. E., Kobro-Flatmoen, A., Halskau, Ø., & Lal, P. (2026) · Lipids in Health and Disease · doi:10.1186/s12944-026-02876-8 · Cited by 2
Modifiable Lifestyle Factors and Cognitive Function: A Population‐Based Study Amongst Nondemented Men
Corney, K. B., Stuart, A. L., Mohebbi, M., Pasco, J. A., Kavanagh, B. E., Sui, S. X., & Williams, L. J. (2024) · Acta Neurologica Scandinavica · doi:10.1155/2024/1935091 · Cited by 2
Regional Differences in Dementia Incidence Among US Veterans
Dintica, C. S., Bahorik, A. L., Xia, F., Boscardin, W. J., & Yaffe, K. S. (2025) · JAMA Neurology · doi:10.1001/jamaneurol.2025.1536 · Cited by 4
Vegetable, Fruit, and Low to Moderate Alcohol Intakes Are Associated with Better Cognition in Middle-Aged and Older Hispanics/Latinos
Hogervorst, E. (2020) · Journal of Nutrition · doi:10.1093/jn/nxaa110 · Cited by 2
Dementia and Diet, Methodological and Statistical Issues: A Pilot Study
Stecker, M. M., Stecker, M., Reiss, A. B., & Kasselman, L. J. (2022) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2022.606424 · Cited by 2
A magyarországi idősek nappali ellátásának helyzete : Igények és lehetőségek a szolgáltatás szervezésében
Vajda, K. (2022) · Máltai Tanulmányok · doi:10.56699/mt.2022.4.2 · Cited by 1
Dementia Appraisal: Overview of Good Clinical Practices, Barriers, and Gaps for Integrated Care
Margarida, A., Meira, B., Raquel, B., Francisco, P. M. B., Henrique, L., & Maria, V. A. (2023) · International Journal of Geriatrics and Gerontology · doi:10.29011/2577-0748.100073 · Cited by 1
Nut Consumption and Long-Term Risk of All-Cause Dementia: Preliminary Findings from Three Prospective Cohort Studies
Zhao, M., Yan, M., Fei, L., Chen, H. C., Wu, M., Li, Y., Huang, L., Shen, J., Liu, G., Guasch‐Ferré, M., et al. (2026) · Nutrients · doi:10.3390/nu18111722 · Cited by 1
APOE-ε4 moderates the association between diet quality and executive function in middle-aged women at increased risk for Alzheimer’s disease
Wessinger, C. M., Park, K. S., DuBois, S. L., Wideman, L., Armstrong, B. D., Vance, J. C., Kibildis, S. W., Som‐Pimpong, H., & Etnier, J. L. (2026) · Journal of Nutritional Science · doi:10.1017/jns.2026.10106 · Cited by 1
Association of vegetable and fruit intake with risk of dementia: 3 prospective studies and meta-analysis of cohort studies
Huang, L., Hailili, G., Zhao, M., Chen, H., Shen, J., Yan, M., Shen, T., Wu, M., Fei, L., Liu, X., et al. (2026) · American Journal of Clinical Nutrition · doi:10.1016/j.ajcnut.2026.101421 · Cited by 1
Demenzerkrankungen – Prävalenz, Bedeutung und Implikationen für die Prävention und Gesundheitsförderung
Förstl, H., & Förstl, S. (2021) · Springer Reference Pflege, Therapie, Gesundheit · doi:10.1007/978-3-662-62426-5_58 · Cited by 1
Subjective cognitive decline and total energy intake: Talk too much?
Kuller, L. H. (2022) · European Journal of Epidemiology · doi:10.1007/s10654-022-00849-6 · Cited by 1
Dietary Tyrosine Intake Is Associated with Locus Coeruleus Integrity, Attentive Cognitive Control and Grey Matter Maintenance: An MRI Structural Study on 398 Healthy Individuals of the Berlin Aging Study-IIPreprint
Plini, E. R. G., Melnychuk, M. C., Harkin, A., Dahl, M. J., McAuslam, M., Kühn, S., Boyle, R. T., Whelan, R., Andrews, R., Düzel, S., et al. (2023) · Preprints.org · doi:10.20944/preprints202304.0406.v1
Circulating metabolomic profile links the MIND diet to cognitive function in middle-aged and older adultsPreprint
Chen, H., Shen, J., Tao, Y., Zhang, Y., Gao, M., Ma, Y., Zheng, Y., Zong, G., Lin, Q., Tong, L., et al. (2023) · Research Square · doi:10.21203/rs.3.rs-3403968/v1 · Cited by 1
Ernährung beeinflusst Demenz nicht
Parhofer, K. (2019) · MMW - Fortschritte der Medizin · doi:10.1007/s15006-019-0444-5
Allein eine „ungesunde“ westliche Ernährung führt langfristig nicht zu kognitiven Defiziten
Duning, T. (2019) · InFo Neurologie + Psychiatrie · doi:10.1007/s15005-019-0083-5
Diet and cognitive decline: considerations for reconciling heterogeneous findings
Gu, X., Koch, M., & Jensen, M. K. (2019) · Current Opinion in Lipidology · doi:10.1097/mol.0000000000000624
Addressing the challenge to identify the role played by lifestyle factors in dementia
Akbaraly, T. N. (2020) · Annals of Translational Medicine · doi:10.21037/atm.2020.01.74
Self-citation
Sugary beverage intake and genetic risk of dementia in relation to incident dementia and brain structure: evidence from the UK BiobankPreprint
Chen, H., Chen, J., Cao, Y., Sun, Y., Huang, L., Ji, J. S., Shen, J., Zheng, Y., Zong, G., & Yuan, C. (2021) · Research Square · doi:10.21203/rs.3.rs-882320/v1
Sugary beverage intake and genetic risk in relation to brain structure and incident dementia: evidence from the UK BiobankPreprint
Chen, H., Chen, J., Cao, Y., Sun, Y., Huang, L., Ji, J. S., Voortman, T., Vernooij, M. W., Shen, J., Zheng, Y., et al. (2021) · Research Square · doi:10.21203/rs.3.rs-882320/v2
Deleterious Effect of Westernized Diet Pattern, Red Meat and High Salt Intake on Left Ventricular Structure and Function in Hypertensive Black Sub-Saharan Africans: A Multicentric Cross Sectional Study
Bernard, K. P., Aliocha, N. N., Roger, K. Z., Annie, N. T., Emmanuel, L. B., Eleuthère, K. V., Jean-René, M. K., & Benjamin, L.-M. (2021) · Journal of Heart Health · doi:10.16966/2379-769x.161
Demenzerkrankungen – Prävalenz, Bedeutung und Implikationen für die Prävention und Gesundheitsförderung
Förstl, H., & Förstl, S. (2020) · Springer Reference Pflege, Therapie, Gesundheit · doi:10.1007/978-3-662-55793-8_58-1 · Cited by 2
Mediterranean-DASH Intervention for Neurodegenerative Delay diet and risk of dementia: three prospective studies and meta-analysis of cohort studiesPreprint
Chen, H., Dhana, K., Huang, Y., Huang, L., Yang, T., Liu, X., van Lent, D. M., Zheng, Y., Ascherio, A., Willett, W. C., et al. (2022) · medRxiv · doi:10.1101/2022.10.16.22281155
Dietary Tyrosine intake is associated with Locus Coeruleus, attention and grey matter maintenance: an MRI structural study on 398 healthy individuals of the Berlin Aging Study-IIPreprint
Plini, E. R. G., Melnychuk, M. C., Harkin, A., Dahl, M. J., McAuslan, M. J., Kühn, S., Boyle, R. T., Whelan, R., Andrews, R., Düzel, S., et al. (2023) · Research Square · doi:10.21203/rs.3.rs-3166636/v1

Authors: Akbaraly, T. N., Singh-Manoux, A., Dugravot, A., Brunner, E. J., Kivimäki, M., & Sabia, S.
Affiliations: Inserm (FR)
Department of Epidemiology and Public Health, University College London, London, England
University College London (GB)
Corresponding author: Akbaraly, Tasnime N.
ORCID: Akbaraly, Tasnime N.
Dugravot, Aline
Brunner, Eric J.
Venue: JAMA
Publisher: American Medical Association (AMA)
Published: 2019-03-12
Volume: 321
Issue: 10
Pages: 957
ISSN: 0002-9955 (ISSN-L)
0098-7484
DOI: 10.1001/jama.2019.1432
PMC: PMC6436698
OpenAlex: W2921906072
Cited by: 121
References: 38
Citations by year: 2026: 12 · 2025: 12 · 2024: 20 · 2023: 19 · 2022: 18 · 2021: 13 · 2020: 16 · 2019: 11
FWCI: 13.35
Type: journal article
Language: en
Open access: green
europepmc.org
Locations: JAMA (publishedVersion)
Europe PMC (PubMed Central) (publishedVersion)
PubMed Central (publishedVersion)
PubMed (publishedVersion)
HAL (submittedVersion)
UCL Discovery (University College London) (submittedVersion)
Funders: British Heart Foundation (RG/16/11/32334, PG/11/63/29011, RG/13/2/30098)
Economic and Social Research Council (ES/J023299/1)
National Institute on Aging (R01AG056477)
Topics: Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Nutritional Studies and Diet
Health Sciences › Medicine › Psychiatry and Mental health › Dementia and Cognitive Impairment Research
Health Sciences › Nursing › Nutrition and Dietetics › Fatty Acid Research and Health
Keywords: dementia risk, Alternative Healthy Eating Index, diet quality, cognitive health, incident dementia, preclinical dementia, dietary intake, food frequency questionnaire, long-term follow-up, cognitive aging, Alzheimer's disease, vascular dementia, dementia subtypes, sex differences, neuroimaging biomarkers, neurodegeneration biomarkers, neuroinflammation
MeSH terms: Diet, Healthy, Energy Intake, Dementia, Diet, Diet Surveys, Factor Analysis, Statistical, Female, Humans, Male, Middle Aged, Risk, Socioeconomic Factors, Cohort Studies, Health Behavior, Incidence, Multivariate Analysis

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Association of Midlife Diet With Subsequent Risk for Dementia

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Self-check

Citations

Cites

Cited by

Related

Metadata

Record

About these checks