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Persistent Symptoms in Patients After Acute COVID-19
Open accessAbstract
case rate of 587 per 100 000.The crude COVID-19 death rate in prisons was 39 deaths per 100 000 prisoners, which was higher than the US population rate of 29 deaths per 100 000 (Table).However, individuals aged 65 years or older comprised a smaller share of the prison population than of the US population (3% vs 16%, respectively) and accounted for 81% of COVID-19 deaths in the US population.The Table provides a standardized calculation showing that the adjusted death rate in the prison population was 3.0 times higher than would be expected if the age and sex distributions of the US and prison populations were equal.The Figure displays the daily trends in cumulative, confirmed cases of COVID-19 in state and federal prisons and the US population from March 31, 2020, to June 6, 2020.The COVID-19 case rate was initially lower in prisons but surpassed the US population on April 14, 2020.The mean daily case growth rate was 8.3% per day in prisons and 3.4% per day in the US population.Discussion | COVID-19 case rates have been substantially higher and escalating much more rapidly in prisons than in the US population.One limitation of the study is that it relied on officially reported data, which may be subject to inaccuracies and reporting delays, but are the only data available.Comprehensive data on testing rates were not available, and testing rates in both prisons and the overall population were uneven, with many facilities testing no prisoners or only symptomatic persons.2,5 Mass testing in select prisons revealed wide COVID-19 outbreaks, with infection rates exceeding 65% in several facilities. 2 Reported case rates for prisoners therefore likely understated the true prevalence of COVID-19 in prisons.A second limitation is that departments of corrections generally did not report demographic data on decedents, and therefore we could not adjust death rates to account for race/ ethnicity and comorbidity.This study focused on prisons but did not include jails or other detention facilities where there have been notable COVID-19 outbreaks.Although some facilities did engage in efforts to control outbreaks, the findings suggest that overall, COVID-19 in US prisons is unlikely to be contained without implementation of more effective infection control.
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“Nevertheless, what emerges from preliminary data is the negative impact of long COVID on quality of life and its effects on patient work ability and social relationships [1,4,19].”
From Female gender is associated with long COVID syndrome: a prospective cohort study (2022) · cites this paper as [4]
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“The high incidence of long COVID within our cohort was similar to that previously reported: more than half of patients reported symptoms lasting more than 2 months after symptom onset [4,5,16,18,19].”
From Female gender is associated with long COVID syndrome: a prospective cohort study (2022) · cites this paper as [4]
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Wang, D., Hu, B., Hu, C., Zhu, F., Liu, X., Zhang, J., Wang, B., Xiang, H., Cheng, Z., Xiong, Y., et al. (2020) · JAMA · doi:10.1001/jama.2020.1585 · Cited by 20,148
La certeza de lo impredecible: Cultura Educación y Sociedad en tiempos de COVID19
Martínez González, M. (2020) · DSPACE System - Metalibrary (University of the Coast) · Cited by 18,463
Wu, Z., & McGoogan, J. M. (2020) · JAMA · doi:10.1001/jama.2020.2648 · Cited by 17,016
Docherty, A. B., Harrison, E. M., Green, C. A., Hardwick, H. E., Pius, R., Norman, L., Holden, K. A., Read, J. M., Dondelinger, F., Carson, G., et al. (2020) · BMJ · doi:10.1136/bmj.m1985 · Cited by 3,481
Post-COVID-19 global health strategies: the need for an interdisciplinary approach
Gemelli Against COVID-19 Post-Acute Care Study Group, Landi, F., Gremese, E., Bernabei, R., Fantoni, M., Gasbarrini, A., Settanni, C. R., Benvenuto, F., Bramato, G., Carfì, A., et al. (2020) · Aging Clinical and Experimental Research · doi:10.1007/s40520-020-01616-x · Cited by 269
Self-citationThe New Challenge of Geriatrics: Saving Frail Older People from the SARS-COV-2 Pandemic Infection,
Landi, F., Barillaro, C., Bellieni, A., Brandi, V., Carfì, A., D'Angelo, M., Fusco, D., Landi, G., Monaco, M. R. L., Martone, A. M., et al. (2020) · The journal of nutrition health & aging · doi:10.1007/s12603-020-1356-x · Cited by 145
Self-citationMeasuring symptomatic and functional recovery in patients with community-acquired pneumonia
Metlay, J. P., Fine, M. J., Schulz, R., Marrie, T. J., Coley, C. M., Kapoor, W. N., & Singer, D. E. (1997) · Journal of General Internal Medicine · doi:10.1046/j.1525-1497.1997.00074.x · Cited by 129
Cited by
Sorted by citations
Items 301–400 of 1,005
Dendritic cell deficiencies persist seven months after SARS-CoV-2 infection
Pérez‐Gómez, A., Vitallé, J., Gasca‐Capote, C., Gutiérrez‐Valencia, A., Trujillo‐Rodríguez, M., Serna‐Gallego, A., Muñoz‐Muela, E., Jiménez‐León, M. R., Benhnia, M. R., Rivas‐Jeremías, I., et al. (2021) · Cellular and Molecular Immunology · doi:10.1038/s41423-021-00728-2 · Cited by 121
Patel, M. A., Knauer, M. J., Nicholson, M., Daley, M., Nynatten, L. R. V., Martin, C. M., Patterson, E. K., Cepinskas, G., Seney, S. L., Dobretzberger, V., et al. (2022) · Molecular Medicine · doi:10.1186/s10020-022-00548-8 · Cited by 129
International travel-related control measures to contain the COVID-19 pandemic: a rapid review
Burns, J., Movsisyan, A., Stratil, J. M., Biallas, R., Coenen, M., Emmert-Fees, K. M. F., Geffert, K., Hoffmann, S., Horstick, O., Laxy, M., et al. (2021) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd013717.pub2 · Cited by 127
Pathophysiology of Post-COVID syndromes: a new perspective
Batiha, G. E., Al-Kuraishy, H. M., Al-Gareeb, A. I., & Welson, N. N. (2022) · Virology Journal · doi:10.1186/s12985-022-01891-2 · Cited by 133
“The spatial and cell‑type distribution of SARS‑CoV‑2 receptor ACE2 in the human and mouse brains.”
BackgroundInfluentialSARS-CoV-2 mediated neuroinflammation and the impact of COVID-19 in neurological disorders
Amruta, N., Chastain, W. H., Paz, M., Solch-Ottaiano, R. J., Murray-Brown, I. C., Befeler, J. B., Gressett, T. E., Longo, M. T., Engler-Chiurazzi, E. B., & Bix, G. J. (2021) · Cytokine & Growth Factor Reviews · doi:10.1016/j.cytogfr.2021.02.002 · Cited by 123
Dinnon, K. H., Leist, S. R., Okuda, K., Dang, H., Fritch, E. J., Gully, K. L., la Cruz, G. D., Evangelista, M. D., Asakura, T., Gilmore, R. C., et al. (2022) · Science Translational Medicine · doi:10.1126/scitranslmed.abo5070 · Cited by 138
Pierce, J. D., Shen, Q., Cintron, S. A., & Hiebert, J. B. (2021) · Nursing Research · doi:10.1097/nnr.0000000000000565 · Cited by 122
“Approximately 70% of persons with these symptoms had been physically fit before the illness and have become sedentary because of the severity of the symptoms (Carfi et al., 2020).”
BackgroundCOVID-19 and Diabetes: A Collision and Collusion of Two Diseases
Feldman, E. L., Savelieff, M. G., Hayek, S. S., Pennathur, S., Kretzler, M., & Pop-Busui, R. (2020) · Diabetes · doi:10.2337/dbi20-0032 · Cited by 136
“Diabetes and COVID-19 sequelae It is becoming clear that COVID-19 survivors suffer from persistent symptoms (83) and may also face a lifetime of sequelae, drawing parallels to SARS and MERS (10; 84).”
BackgroundSequelae in adults at 12 months after mild‐to‐moderate coronavirus disease 2019 (COVID‐19)
Boscolo‐Rizzo, P., Guida, F., Polesel, J., Marcuzzo, A. V., Capriotti, V., D’Alessandro, A., Zanelli, E., Marzolino, R., Lazzarin, C., Antonucci, P., et al. (2021) · International Forum of Allergy & Rhinology · doi:10.1002/alr.22832 · Cited by 121
Holmes, E. C., Wist, J., Masuda, R., Lodge, S., Nitschke, P., Kimhofer, T., Loo, R. L., Begum, S., Boughton, B. A., Yang, R., et al. (2021) · Journal of Proteome Research · doi:10.1021/acs.jproteome.1c00224 · Cited by 115
Rogers, J. P., Watson, C. J., Badenoch, J., Cross, B., Butler, M., Song, J., Hafeez, D., Morrin, H., Rengasamy, E. R., Thomas, L., et al. (2021) · Journal of Neurology Neurosurgery & Psychiatry · doi:10.1136/jnnp-2021-326405 · Cited by 133
Fernández‐de‐las‐Peñas, C., Navarro‐Santana, M. J., Plaza‐Manzano, G., Palacios‐Ceña, D., & Arendt‐Nielsen, L. (2021) · Pain · doi:10.1097/j.pain.0000000000002496 · Cited by 125
Thye, A. Y.-K., Law, J. W., Tan, L. T., Pusparajah, P., Ser, H., Thurairajasingam, S., Letchumanan, V., & Lee, L. (2022) · Biology · doi:10.3390/biology11010061 · Cited by 122
Long COVID: The Nature of Thrombotic Sequelae Determines the Necessity of Early Anticoagulation
Wang, C., Yu, C., Jing, H., Wu, X., Novakovic, V. A., Xie, R., & Shi, J. (2022) · Frontiers in Cellular and Infection Microbiology · doi:10.3389/fcimb.2022.861703 · Cited by 124
“Long COVID often leads to chronic hypoxia with pulmonary vascular changes and decreased lung function (Carfì et al., 2020; Caruso et al., 2021; Cueto-Robledo et al., 2022).”
BackgroundTreatment, Persistent Symptoms, and Depression in People Infected with COVID-19 in Bangladesh
Islam, M. S., Ferdous, M. Z., Islam, U. S., Mosaddek, A. S. M., Potenza, M. N., & Pardhan, S. (2021) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph18041453 · Cited by 117
The Impact of Post-COVID-19 Syndrome on Self-Reported Physical Activity
Delbressine, J. M., Machado, F. V. C., Goërtz, Y. M. J., Herck, M. V., Meys, R., Houben‐Wilke, S., Burtin, C., Franssen, F. M. E., Spies, Y., Vijlbrief, H., et al. (2021) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph18116017 · Cited by 127
Visco, V., Vitale, C., Rispoli, A., Izzo, C., Virtuoso, N., Ferruzzi, G. J., Santopietro, M., Melfi, A., Rusciano, M. R., Maglio, A., et al. (2022) · Journal of Clinical Medicine · doi:10.3390/jcm11030524 · Cited by 119
Shiers, S. I., Ray, P. R., Wangzhou, A., Sankaranarayanan, I., Tatsui, C. E., Rhines, L. D., Li, Y., Uhelski, M. L., Dougherty, P. M., & Price, T. J. (2020) · Pain · doi:10.1097/j.pain.0000000000002051 · Cited by 116
“There are many currently unexplained neurological features in patients with COVID-19,(16,18) including persistent symptoms such as joint pain and headache linked to nociceptor function.(7) It is mysterious how the virus enters the nervous system as most neurons do not express ACE2.”
BackgroundLittlefield, K. M., Watson, R. O., Schneider, J. M., Neff, C. P., Yamada, E., Zhang, M., Campbell, T., Falta, M. T., Jolley, S. E., Fontenot, A. P., et al. (2022) · PLoS Pathogens · doi:10.1371/journal.ppat.1010359 · Cited by 115
Chuang, H., Lin, C.-W., Hsiao, M., Wang, T., & Liang, H. (2023) · Journal of the Formosan Medical Association · doi:10.1016/j.jfma.2023.03.022 · Cited by 125
“Overall, the prevalence of different symptoms was found to gradually decrease over 6e12 months.(8,9,12) Cough and dyspnea are prevalent within 2e3 months after infection, the rates of which decrease at 6 months, while fatigue and neuropsychiatric symptoms tend to persist for a longer period of time.”
BackgroundLong COVID or post COVID-19 syndrome
Lechner‐Scott, J., Levy, M., Hawkes, C. H., Yeh, E. A., & Giovannoni, G. (2021) · Multiple Sclerosis and Related Disorders · doi:10.1016/j.msard.2021.103268 · Cited by 138
Pathological findings in organs and tissues of patients with COVID-19: A systematic review
Peiris, S., Mesa, H. A., Aysola, A. E., Manivel, J. C., Toledo, J., Borges-Sa, M., Aldighieri, S., & Revéiz, L. (2021) · PLoS ONE · doi:10.1371/journal.pone.0250708 · Cited by 117
“The pathogenesis of this “post-COVID-19 condition” is currently unknown [59], but has been hypothesized to be related to virally induced endothelial damage in the microcirculation [36].”
BackgroundAssessment of musculoskeletal pain, fatigue and grip strength in hospitalized patients with COVID-19
Tüzün, Ş., Keles, A., Okutan, D., Yildiran, T., & Palamar, D. (2021) · European Journal of Physical and Rehabilitation Medicine · doi:10.23736/s1973-9087.20.06563-6 · Cited by 114
Ong, S. W. X., Fong, S., Young, B. E., Chan, Y., Lee, B. T. K., Amrun, S. N., Chee, R. S., Yeo, N. K., Tambyah, P. A., Pada, S., et al. (2021) · Open Forum Infectious Diseases · doi:10.1093/ofid/ofab156 · Cited by 113
“6%, 20%, 32%, and 4% respectively) [6-9], we showed that cytokine expression for proinflammatory cytokines was only marginally different in follow-up samples for those with initial severe disease compared with asymptomatic and mildly infected”
BackgroundInappropriate sinus tachycardia in post-COVID-19 syndrome
Aranyo, J. A., Bazán, V., Lladós, G., Domínguez, M. J., Bisbal, F., Massanella, M., Sarrias, A., Adeliño, R., Riverola, A., Paredes, R., et al. (2022) · Scientific Reports · doi:10.1038/s41598-021-03831-6 · Cited by 114
Exploring the pathophysiology of post-sepsis syndrome to identify therapeutic opportunities
van der Slikke, E. C., An, A. Y., Hancock, R. E. W., & Bouma, H. R. (2020) · EBioMedicine · doi:10.1016/j.ebiom.2020.103044 · Cited by 124
“Similarly, almost half of acute COVID-19 survivors reported decreased QoL 60 days after fi rst onset of symptoms compared to before developing COVID-19, mainly due to fatigue and joint pain [115].”
Yoo, S. M., Liu, T. C., Motwani, Y., Sim, M., Viswanathan, N., Samras, N., Hsu, F., & Wenger, N. S. (2022) · Journal of General Internal Medicine · doi:10.1007/s11606-022-07523-3 · Cited by 116
“PASC definition were fatigue then shortness of breath, in line with existing studies.(1,2) Although fatigue was the most common persistent symptom in hospitalized and non-hospitalized patients, this was followed by loss of sense of smell in outpatients and shortness of breath in inpatients, which is in line with previ…”
ResultPost–COVID-19 Conditions Among Children 90 Days After SARS-CoV-2 Infection
Funk, A. L., Kuppermann, N., Florin, T. A., Tancredi, D. J., Xie, J., Kim, K., Finkelstein, Y., Neuman, M. I., Salvadori, M. I., Yock‐Corrales, A., et al. (2022) · JAMA Network Open · doi:10.1001/jamanetworkopen.2022.23253 · Cited by 114
Joshee, S. R., Vatti, N., & Chang, C. C.-C. (2022) · Mayo Clinic Proceedings · doi:10.1016/j.mayocp.2021.12.017 · Cited by 118
“Patients should resume regular activities 6 to 8 weeks post-discharge, but this may be more challenging in patients who have severe disease, extended hospital stays, or prolonged symptoms.(19,128) Even if a formal exercise and exertional desaturation assessment cannot be conducted in patients with COVID-19, they shoul…”
Munipalli, B., Seim, L. A., Dawson, N. L., Knight, D. R. T., & Dabrh, A. M. A. (2022) · SN Comprehensive Clinical Medicine · doi:10.1007/s42399-022-01167-4 · Cited by 118
Reinfection With SARS-CoV-2: Implications for Vaccines
Cohen, J. I., & Burbelo, P. D. (2020) · Clinical Infectious Diseases · doi:10.1093/cid/ciaa1866 · Cited by 111
Post-acute sequelae of COVID-19: Evidence of mood & cognitive impairment
Lamontagne, S. J., Winters, M. F., Pizzagalli, D. A., & Olmstead, M. C. (2021) · Brain Behavior & Immunity - Health · doi:10.1016/j.bbih.2021.100347 · Cited by 120
“Indeed, many survivors develop chronic and debilitating symptoms long after viral recovery, despite mild illness severity at onset (Carfi et al., 2020), pointing to residual effects that span multiple organ systems within the peripheral and central nervous system (CNS).”
Persistent self-reported changes in hearing and tinnitus in post-hospitalisation COVID-19 cases
Munro, K. J., Uus, K., Almufarrij, I., Chaudhuri, N., & Yioe, V. (2020) · International Journal of Audiology · doi:10.1080/14992027.2020.1798519 · Cited by 110
“However, it is becoming increasingly recognised that presenting symptoms of COVID-19, including fatigue, dyspnea, joint pain and chest pain, persist long after discharge from hospital (Carfi et al. 2020).”
BackgroundMotiejūnaitė, J., Balagny, P., Arnoult, F., Mangin, L., Bancal, C., d’Ortho, M., & Frija‐Masson, J. (2021) · Frontiers in Physiology · doi:10.3389/fphys.2020.614590 · Cited by 114
SARS-CoV-2 vaccines: a triumph of science and collaboration
Golob, J. L., Lugogo, N. L., Lauring, A. S., & Lok, A. S.-F. (2021) · JCI Insight · doi:10.1172/jci.insight.149187 · Cited by 113
“Even in those who survive SARS-CoV-2 infection, a substantial percentage suffer persistent and debilitating symptoms (1, 2).”
BackgroundGonzález-Hermosillo, J. A., Martínez-López, J., Carrillo-Lampón, S. A., Ruiz-Ojeda, D., Herrera-Ramírez, S., Amezcua-Guerra, L. M., & Martínez-Alvarado, M. R. (2021) · Brain Sciences · doi:10.3390/brainsci11060760 · Cited by 116
Bitirgen, G., Korkmaz, C., Zamanı, A., Özkağnıcı, A., Zengįn, N., Ponirakis, G., & Malik, R. A. (2021) · British Journal of Ophthalmology · doi:10.1136/bjophthalmol-2021-319450 · Cited by 111
Khan, S. R., Shilen, A., Heslin, K. M., Ishimwe, P., Allen, A. M., Jacobs, E. T., & Farland, L. V. (2021) · American Journal of Obstetrics and Gynecology · doi:10.1016/j.ajog.2021.09.016 · Cited by 110
Cañas, C. A. (2020) · Medical Hypotheses · doi:10.1016/j.mehy.2020.110345 · Cited by 116
“syndrome, and myalgias, among others [23,24].”
Occupation and risk of severe COVID-19: prospective cohort study of 120,075 UK Biobank participantsPreprint
Mutambudzi, M. S., Niedzwiedz, C. L., Macdonald, E. B., Leyland, A. H., Mair, F. S., Anderson, J. J., Celis-Morales, C. A., Cleland, J. G. F., Forbes, J., Gill, J. M. R., et al. (2020) · medRxiv · doi:10.1101/2020.05.22.20109892 · Cited by 109
COVID and Cardiovascular Disease: What We Know in 2021
Chilazi, M. J., Duffy, E. Y., Thakkar, A., & Michos, E. D. (2021) · Current Atherosclerosis Reports · doi:10.1007/s11883-021-00935-2 · Cited by 115
Post-COVID-19 pneumonia lung fibrosis: a worrisome sequelae in surviving patients
Ali, R. M. M., & Ghonimy, M. B. I. (2021) · The Egyptian Journal of Radiology and Nuclear Medicine · doi:10.1186/s43055-021-00484-3 · Cited by 107
“COVID-19 sequelae may range from mild form of fatigue to serious forms requiring long-term oxygen therapy or even lung transplantation owing to pulmonary fibrosis [3].”
BackgroundDamage to endothelial barriers and its contribution to long COVID
Wu, X., Xiang, M., Jing, H., Wang, C., Novakovic, V. A., & Shi, J. (2023) · Angiogenesis · doi:10.1007/s10456-023-09878-5 · Cited by 111
Racial and Ethnic Disparities in COVID-19: Evidence from Six Large Cities
Benitez, J. A., Courtemanche, C., & Yelowitz, A. S. (2020) · Journal of Economics Race and Policy · doi:10.1007/s41996-020-00068-9 · Cited by 109
“3 Even after discharge from a hospital, persistent symptoms may remain (Carfì et al. 2020).”
Assessment of activities of daily living in patients post COVID-19: a systematic review
Pizarro-Pennarolli, C., Sánchez-Rojas, C., Torres‐Castro, R., Vera‐Uribe, R., Sanchez‐Ramirez, D. C., Vasconcello‐Castillo, L., Solís‐Navarro, L., & Rivera‐Lillo, G. (2021) · PeerJ · doi:10.7717/peerj.11026 · Cited by 106
Fleischmann-Struzek, C., Rose, N., Freytag, A., Spoden, M., Prescott, H. C., Schettler, A., Wedekind, L., Ditscheid, B., Storch, J., Born, S., et al. (2021) · JAMA Network Open · doi:10.1001/jamanetworkopen.2021.34290 · Cited by 106
Molnupiravir and risk of post-acute sequelae of covid-19: cohort study
Xie, Y., Choi, T., & Al‐Aly, Z. (2023) · BMJ · doi:10.1136/bmj-2022-074572 · Cited by 106
The Pathogenesis and Long-Term Consequences of COVID-19 Cardiac Injury
Siripanthong, B., Asatryan, B., Hanff, T. C., Chatha, S., Khanji, M. Y., Ricci, F., Muser, D., Ferrari, V. A., Nazarian, S., Santangeli, P., et al. (2022) · JACC Basic to Translational Science · doi:10.1016/j.jacbts.2021.10.011 · Cited by 102
Sriram, K., & Insel, P. A. (2020) · Physiological Reviews · doi:10.1152/physrev.00035.2020 · Cited by 107
“FIGURE 5, bottom, relates disease severity with thromboinflammation, (adaptive) immune response, and viral clearance in patients with severe disease, in which SARS-CoV-2 infection results in extensive pulmonary and systemic effects (154), perhaps leading to death or necessitating prolonged recovery in patients who sur…”
BackgroundKlein, H., Asseo, K., Karni, N., Benjamini, Y., Nir‐Paz, R., Muszkat, M., Israel, S., & Niv, M. Y. (2021) · Clinical Microbiology and Infection · doi:10.1016/j.cmi.2021.02.008 · Cited by 105
“Moreover, the symptoms' order of appearance, severity, duration and lack of resolution have only been partly studied [13,14] and are the focus of the current study.”
Radiological and functional lung sequelae of COVID-19: a systematic review and meta-analysis
So, M., Kabata, H., Fukunaga, K., Takagi, H., & Kuno, T. (2021) · BMC Pulmonary Medicine · doi:10.1186/s12890-021-01463-0 · Cited by 114
“such as fatigue, dyspnea, joint pain, and chest pain in patients discharged from hospital at 60 days after symptom onset were reported [4].”
BackgroundKaraarslan, F., Güneri, F. D., & Kardeş, S. (2021) · Rheumatology International · doi:10.1007/s00296-021-04882-8 · Cited by 110
Tleyjeh, I. M., Saddik, B. A., AlSwaidan, N., Alanazi, A. S., Ramakrishnan, R. K., Alhazmi, D., Aloufi, A., AlSumait, F., Berbari, E. F., & Halwani, R. (2021) · PLoS ONE · doi:10.1371/journal.pone.0260568 · Cited by 117
“4% of the cohort experienced the persistence of at least one symptom after recovery at their 2-month follow-up [4].”
BackgroundHossain, M. A., Hossain, K. M. A., Saunders, K., Uddin, Z., Walton, L. M., Raigangar, V. L., Sakel, M., Shafin, R., Hossain, M. S., Kabir, M. F., et al. (2021) · BMJ Global Health · doi:10.1136/bmjgh-2021-006838 · Cited by 112
Sun, D., Sang, Z., Kim, Y. J., Xiang, Y., Cohen, T., Belford, A. K., Huet, A., Conway, J. F., Sun, J., Taylor, D. J., et al. (2021) · Nature Communications · doi:10.1038/s41467-021-24963-3 · Cited by 96
COVID-19 detection in cough, breath and speech using deep transfer learning and bottleneck features
Pahar, M., Klopper, M., Warren, R. M., & Niesler, T. (2021) · Computers in Biology and Medicine · doi:10.1016/j.compbiomed.2021.105153 · Cited by 109
“Caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), this disease affects the respiratory system and includes symptoms like fatigue, dry cough, shortness of breath, joint pain, muscle pain, gastrointestinal symptoms and loss of smell or taste [1,2].”
BackgroundCOVID-19 and the Vasculature: Current Aspects and Long-Term Consequences
Martínez-Salazar, B., Holwerda, M., Stüdle, C., Piragyte, I., Mercader, N., Engelhardt, B., Rieben, R., & Döring, Y. (2022) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2022.824851 · Cited by 106
Remodeling of T Cell Dynamics During Long COVID Is Dependent on Severity of SARS-CoV-2 Infection
Wiech, M., Chrościcki, P., Swatler, J., Stępnik, D., Biasi, S. D., Hampel, M., Brewińska‐Olchowik, M., Maliszewska, A., Sklinda, K., Durlik, M., et al. (2022) · Frontiers in Immunology · doi:10.3389/fimmu.2022.886431 · Cited by 106
Pinzon, R. T., Wijaya, V. O., Jody, A. A., Nunsio, P. N., & Buana, R. B. (2022) · Journal of Infection and Public Health · doi:10.1016/j.jiph.2022.06.013 · Cited by 108
Post-discharge chest CT findings and pulmonary function tests in severe COVID-19 patients
Balbi, M., Conti, C., Imeri, G., Caroli, A., Surace, A., Corsi, A., Mercanzin, E., Arrigoni, A., Villa, G., Marco, F. D., et al. (2021) · European Journal of Radiology · doi:10.1016/j.ejrad.2021.109676 · Cited by 106
Anticipating the long-term cardiovascular effects of COVID-19
Becker, R. C. (2020) · Journal of Thrombosis and Thrombolysis · doi:10.1007/s11239-020-02266-6 · Cited by 100
Chevinsky, J., Tao, G., Lavery, A. M., Kukielka, E. A., Click, E. S., Malec, D. J., Kompaniyets, L., Bruce, B. B., Yusuf, H. R., Goodman, A. B., et al. (2021) · Clinical Infectious Diseases · doi:10.1093/cid/ciab338 · Cited by 103
Naeije, R., & Caravita, S. (2021) · European Respiratory Journal · doi:10.1183/13993003.01763-2021 · Cited by 101
Ioannou, G. N., Baraff, A. J., Fox, A., Shahoumian, T. A., Hickok, A. W., O’Hare, A. M., Bohnert, A. S. B., Boyko, E. J., Maciejewski, M. L., Bowling, C. B., et al. (2022) · JAMA Network Open · doi:10.1001/jamanetworkopen.2022.24359 · Cited by 99
Sokol, H., Contreras, V., Maisonnasse, P., Desmons, A., Delache, B., Sencio, V., Machelart, A., Brisebarre, A., Humbert, L., Deryuter, L., et al. (2021) · Gut Microbes · doi:10.1080/19490976.2021.1893113 · Cited by 103
Long-haul COVID: healthcare utilization and medical expenditures 6 months post-diagnosis
Koumpias, A. M., Schwartzman, D. A., & Fleming, O. (2022) · BMC Health Services Research · doi:10.1186/s12913-022-08387-3 · Cited by 98
Lam, I. C. H., Wong, C. K. H., Zhang, R., Chui, C. S. L., Lai, F. T. T., Li, X., Chan, E. W., Luo, H., Zhang, Q., Man, K. K. C., et al. (2023) · EClinicalMedicine · doi:10.1016/j.eclinm.2023.102000 · Cited by 103
“8,9 A retrospective cohort study in the US evaluated the risk of clinical sequelae during the post-acute phase of COVID-19 infection.”
Munawar, H. S., Khan, S. I., Qadir, Z., Kouzani, A. Z., & Mahmud, M. A. P. (2021) · Sustainability · doi:10.3390/su13031276 · Cited by 99
“The transfer can be direct through contact with the infected person or indirect by touching the infected surfaces [2].”
BackgroundDeterminants of persistent post-COVID-19 symptoms: value of a novel COVID-19 symptom score
Galal, I., Hussein, A. A. R. M., Amin, M. T., Saad, M. M., Zayan, H. E. E., Abdelsayed, M. Z., Moustafa, M. M., Ezzat, A. R., Helmy, R. E., Abd-Elaal, H., et al. (2021) · Egyptian Journal of Bronchology · doi:10.1186/s43168-020-00049-4 · Cited by 110
Exercise Ventilatory Inefficiency in Post-COVID-19 Syndrome: Insights from a Prospective Evaluation
Aparisi, Á., Ybarra-Falcón, C., Gomez, M. G., Tobar, J., Iglesias-Echeverría, C., Largo, S. J., Ladrón, R., Uribarri, A., Catalá, P., Hinojosa, W., et al. (2021) · Journal of Clinical Medicine · doi:10.3390/jcm10122591 · Cited by 109
“[4] Jama/2020 Single-center Prospective 143 2 months Dyspnea 43.”
BackgroundSerum Metabolic Profile in Patients With Long-Covid (PASC) Syndrome: Clinical Implications
Pasini, E., Corsetti, G., Romano, C., Scarabelli, T. M., Chen-Scarabelli, C. A., Saravolatz, L. I. I., & Dioguardi, F. S. (2021) · Frontiers in Medicine · doi:10.3389/fmed.2021.714426 · Cited by 101
“Interestingly, several recent studies show that 50–70% of patients still experience a variety of symptoms up to 2–6 months following total recovery from the acute phase of COVID-19 infection (6, 7).”
BackgroundInfluentialAcute and Post-Acute Neurological Complications of COVID-19
Al-Ramadan, A., Rabab’h, O., Shah, J., & Gharaibeh, A. (2021) · Neurology International · doi:10.3390/neurolint13010010 · Cited by 98
Cardiorespiratory Abnormalities in Patients Recovering from Coronavirus Disease 2019
Szekely, Y., Lichter, Y., Sadon, S., Lupu, L., Taieb, P., Banai, A., Sapir, O. P. R., Granot, Y. N., Hochstadt, A., Friedman, S., et al. (2021) · Journal of the American Society of Echocardiography · doi:10.1016/j.echo.2021.08.022 · Cited by 109
One-year mental health outcomes in a cohort of COVID-19 survivors
Mazza, M. G., Palladini, M., LORENZO, R. D., Bravi, B., Poletti, S., Furlan, R., Ciceri, F., Vai, B., Bollettini, I., Melloni, E. M. T., et al. (2021) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2021.11.031 · Cited by 102
“Furthermore, persistent and prolonged symptoms, similarly to previous coronavirus outbreaks (Moldofsky and Patcai, 2011), have been observed in several patients recovered from the acute phase (Carfì et al., 2020).”
The Female-Predominant Persistent Immune Dysregulation of the Post-COVID Syndrome
Ganesh, R., Grach, S. L., Ghosh, A. K., Bierle, D. M., Salonen, B. R., Collins, N. M., Joshi, A. Y., Boeder, N., Anstine, C. V., Mueller, M. R., et al. (2022) · Mayo Clinic Proceedings · doi:10.1016/j.mayocp.2021.11.033 · Cited by 105
“2 experience persistent symptoms months after resolution of acute illness.(1-7) These persistent symptoms have been described by several terms, including post-COVID syndrome (PoCoS), posteacute COVID-19, and long-haul COVID.”
BackgroundInfluentialGelfand, J. M., Armstrong, A. W., Bell, S. J., Anesi, G. L., Blauvelt, A., Calabrese, C. M., Dommasch, E. D., Feldman, S. R., Gladman, D. D., Kircik, L., et al. (2021) · Journal of the American Academy of Dermatology · doi:10.1016/j.jaad.2020.12.058 · Cited by 101
‘Long COVID’: persistent COVID-19 symptoms in survivors managed in Lagos State, Nigeria
Osikomaiya, B. I., Erinoso, O. A., Wright, O., Odusola, A. O., Thomas, B., Adeyemi, O., Bowale, A., Adejumo, O. A., Falana, A., Abdus-Salam, I. A., et al. (2021) · BMC Infectious Diseases · doi:10.1186/s12879-020-05716-x · Cited by 96
“Persistent COVID-19 symptoms- ‘long COVID’- have been reported to have similarities with other syndromes such as myalgic encephalomyelitis, or chronic fatigue syndrome which occur after viral infections [3, 11, 14] However, the exact pathophysiology of ‘long COVID’ is not yet understood.”
BackgroundResultEpidemiological and clinical perspectives of long COVID syndrome
Huerne, K., Filion, K. B., Grad, R. M., Ernst, P., Gershon, A. S., & Eisenberg, M. J. (2023) · American Journal of Medicine Open · doi:10.1016/j.ajmo.2023.100033 · Cited by 110
Prescott, H. C., & Girard, T. D. (2020) · JAMA · doi:10.1001/jama.2020.14103 · Cited by 103
Die COVID-19-Pandemie als Herausforderung für die psychische Gesundheit
Brakemeier, E., Wirkner, J., Knaevelsrud, C., Wurm, S., Christiansen, H., Lueken, U., & Schneider, S. (2020) · Zeitschrift für Klinische Psychologie und Psychotherapie · doi:10.1026/1616-3443/a000574 · Cited by 109
Causation or confounding: why controls are critical for characterizing long COVID
Amin‐Chowdhury, Z., & Ladhani, S. N. (2021) · Nature Medicine · doi:10.1038/s41591-021-01402-w · Cited by 98
The contested meaning of “long COVID” – Patients, doctors, and the politics of subjective evidence
Roth, P. H., & Bondio, M. G. (2021) · Social Science & Medicine · doi:10.1016/j.socscimed.2021.114619 · Cited by 96
Clemente‐Suárez, V. J., Beltrán-Velasco, A. I., Ramos‐Campo, D. J., Mielgo‐Ayuso, J., Nikolaidis, P. Τ., Belando‐Pedreño, N., & Tornero-Aguilera, J. F. (2021) · Physiology & Behavior · doi:10.1016/j.physbeh.2021.113667 · Cited by 107
Tosato, M., Calvani, R., Picca, A., Ciciarello, F., Galluzzo, V., Coelho‐Júnior, H. J., Giorgio, A. D., Mario, C. D., Gervasoni, J., Gremese, E., et al. (2022) · Nutrients · doi:10.3390/nu14234984 · Cited by 96
Self-citationFung, K. W., Baye, F. M., Baik, S. H., Zheng, Z., & McDonald, C. J. (2023) · PLoS Medicine · doi:10.1371/journal.pmed.1004194 · Cited by 105
Nguyen, N. N., Hoang, V. T., Dao, T. L., Dudouet, P., Eldin, C., & Gautret, P. (2022) · European Journal of Clinical Microbiology & Infectious Diseases · doi:10.1007/s10096-022-04417-4 · Cited by 91
Prevalence and characteristics of new‐onset pain in COVID‐19 survivours, a controlled study
Soares, F. H. C., Kubota, G. T., Fernandes, A. M., Rebouças, B. H., Couras, C., Costa, B. V., Lapa, J. D. D. S., Braga, L. M., de Almeida, M. M., da Cunha, P. H. M., et al. (2021) · European Journal of Pain · doi:10.1002/ejp.1755 · Cited by 101
Anand, U., Cabreros, C., Mal, J., Ballesteros, F., Sillanpää, M. E. T., Tripathi, V. S., & Bontempi, E. (2021) · Environmental Research · doi:10.1016/j.envres.2021.111126 · Cited by 97
Role of miR-2392 in driving SARS-CoV-2 infection
McDonald, J. T., Enguita, F. J., Taylor, D. M., Griffin, R. J., Priebe, W., Emmett, M. R., Sajadi, M. M., Harris, A. D., Clement, J., Dybas, J. M., et al. (2021) · Cell Reports · doi:10.1016/j.celrep.2021.109839 · Cited by 96
Lage, S. L., Amaral, E. P., Hilligan, K. L., Laidlaw, E., Rupert, A. W., Namasivayan, S., Rocco, J. M., Galindo, F., Kellogg, A., Kumar, P. N., et al. (2022) · Frontiers in Immunology · doi:10.3389/fimmu.2021.799558 · Cited by 98
Besnier, F., Bérubé, B., Malo, J., Gagnon, C., Grégoire, C., Juneau, M., Simard, F., L’Allier, P. L., Nigam, A., Iglesies‐Grau, J., et al. (2022) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph19074133 · Cited by 97
“Some symptoms such as dyspnoea and fatigue appear to persist for several months after recovery in about 50% of cases [3,4].”
BackgroundHyperventilation as one of the mechanisms of persistent dyspnoea in SARS-CoV-2 survivors
Motiejūnaitė, J., Balagny, P., Arnoult, F., Mangin, L., Bancal, C., Vidal‐Petiot, E., Flamant, M., Jondeau, G., Solal, A. C., d’Ortho, M., et al. (2021) · European Respiratory Journal · doi:10.1183/13993003.01578-2021 · Cited by 95
Salmon, D., Slama, D., de Broucker, T., Karmochkine, M., Pavie, J., Sorbets, E., Etienne, N., Batisse, D., Spiridon, G., Baut, V. L., et al. (2020) · Journal of Infection · doi:10.1016/j.jinf.2020.12.002 · Cited by 91
COVID‐19: Current knowledge in clinical features, immunological responses, and vaccine development
Singh, R., Kang, A., Luo, X., Jeyanathan, M., Gillgrass, A. E., Afkhami, S., & Xing, Z. (2021) · The FASEB Journal · doi:10.1096/fj.202002662r · Cited by 101
Fatigue following COVID-19 infection is not associated with autonomic dysfunction
Townsend, L., Moloney, D. J., Finucane, C., McCarthy, K., Bergin, C. J., Bannan, C., & Kenny, R. A. (2021) · PLoS ONE · doi:10.1371/journal.pone.0247280 · Cited by 98
“The primary complaint appears to be persistent fatigue and we have previously demonstrated a high prevalence of fatigue in convalescent COVID-19 patients [7,8].”
BackgroundHayden, M. C., Limbach, M., Schüler, M., Merkl, S., Schwarzl, G., Jakab, K., Nowak, D., & Schultz, K. (2021) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph18179001 · Cited by 98
Chung, Y.-S., Lam, C.-Y., Tan, P.-H., Tsang, H. F., & Wong, S. C. C. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms25158155 · Cited by 120
Myopathic changes in patients with long-term fatigue after COVID-19
Agergaard, J., Leth, S., Pedersen, T. H., Harbo, T., Blicher, J. U., Karlsson, P., Østergaard, L. J., Andersen, H., & Tankişi, H. (2021) · Clinical Neurophysiology · doi:10.1016/j.clinph.2021.04.009 · Cited by 94
“In a smaller cohort of 157 patients at a mean of 60 days follow-up, fatigue was seen in 53.1% of patients and muscle pain in around 5% (Carfi et al., 2020).”
InfluentialPreparing for the long-haul: Autonomic complications of COVID-19
Larsen, N. W., Stiles, L. E., & Miglis, M. G. (2021) · Autonomic Neuroscience · doi:10.1016/j.autneu.2021.102841 · Cited by 94
Long, Q., Li, J., Hu, X., Bai, Y., Zheng, Y., & Gao, Z. (2021) · Frontiers in Medicine · doi:10.3389/fmed.2021.702635 · Cited by 96
“A recent study (6) reported that 32% of hospitalized COVID-19 patients presented with one to two symptoms at 2 months after disease onset, 55% presented three or more symptoms, while only 12.”
Background
Metadata
- Authors
- Carfì, A., Bernabei, R., Landi, F., & for the Gemelli Against COVID-19 Post-Acute Care Study Group
- Affiliations
- Agostino Gemelli University Polyclinic (IT)
- Corresponding author
- Carfì, Angelo
- Venue
- JAMA
- Publisher
- American Medical Association (AMA)
- Published
- 2020-08-11
- Volume
- 324
- Issue
- 6
- Pages
- 603
- ISSN
- 0002-9955 (ISSN-L)
- 0098-7484
- PMC
- PMC7349096
- OpenAlex
- W3041493976
- Cited by
- 4,561
- References
- 7
- Citations by year
- 2026: 139 · 2025: 292 · 2024: 495 · 2023: 827 · 2022: 1183 · 2021: 1373 · 2020: 245
- FWCI
- 393.49
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- JAMA (publishedVersion)
- Europe PMC (PubMed Central) (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Funders
- University of Pennsylvania
- Topics
- Health Sciences › Medicine › Clinical Neurology › Long-Term Effects of COVID-19
- Health Sciences › Medicine › Infectious Diseases › COVID-19 Clinical Research Studies
- Physical Sciences › Mathematics › Modeling and Simulation › COVID-19 epidemiological studies
- Keywords
- COVID-19 pandemic, long COVID, post-acute symptoms, prisoners, prison population, COVID-19 mortality, COVID-19 case rates, infection control, jails, detention centers, COVID-19 outbreak
- MeSH terms
- Betacoronavirus, COVID-19, SARS-CoV-2, Adult, Aged, Chest Pain, Dyspnea, Fatigue, Female, Follow-Up Studies, Humans, Italy, Male, Middle Aged, Pneumonia, Viral, Coronavirus Infections, Arthralgia, Pandemics, Symptom Assessment
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