Telomere Length Shortening and Alzheimer Disease—A Mendelian Randomization Study
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Genetic variations in genes involved in telomere maintenance correlate with Alzheimer's disease susceptibility.
“Supporting this idea, genetic variations in genes involved in telomere maintenance have been shown to correlate with AD susceptibility [121].”
From Senescence-related impairment of autophagy induces toxic intraneuronal amyloid-β accumulation in a mouse model of amyloid pathology (2023) · cites this paper as [121]
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Meta-Analysis of 74,046 Individuals Identifies 11 New Susceptibility Loci for Alzheimer’s Disease
(EADI), E. A. D. I., Lambert, J.-C., (GERAD), G. A. E. R. I. A. D., Alzheimer's Disease Genetic Consortium (ADGC), (CHARGE), C. F. H. A. A. R. I. G. E., Ibrahim-Verbaas, C. A., Harold, D., Naj, A. C., Sims, R., Bellenguez, C., et al. (2013) · Nature Genetics · doi:10.1038/ng.2802 · Cited by 4,336 · see citing works
EPIC- InterAct Consortium, Burgess, S., Scott, R. A., Timpson, N. J., Davey Smith, G., & Thompson, S. G. (2015) · European Journal of Epidemiology · doi:10.1007/s10654-015-0011-z · Cited by 1,803 · see citing works
Telomeres and human disease: ageing, cancer and beyond
Blasco, M. A. (2005) · Nature Reviews Genetics · doi:10.1038/nrg1656 · Cited by 1,690 · see citing works
Identification of seven loci affecting mean telomere length and their association with disease
CARDIoGRAM consortium, Codd, V., Nelson, C. P., Albrecht, E., Mangino, M., Deelen, J., Buxton, J. L., Hottenga, J. J., Fischer, K., Esko, T., et al. (2013) · Nature Genetics · doi:10.1038/ng.2528 · Cited by 933 · see citing works
Self-citationThe Role of Adiposity in Cardiometabolic Traits: A Mendelian Randomization Analysis
Fall, T., Hägg, S., Mägi, R., Ploner, A., Fischer, K., Horikoshi, M., Sarin, A.-P., Thorleifsson, G., Ladenvall, C., Kals, M., et al. (2013) · PLoS Medicine · doi:10.1371/journal.pmed.1001474 · Cited by 203 · see citing works
Self-citationAssociation of Shorter Leukocyte Telomere Repeat Length With Dementia and Mortality
Honig, L. S., Kang, M. S., Schupf, N., Lee, J. H., & Mayeux, R. P. (2012) · Archives of Neurology · doi:10.1001/archneurol.2012.1541 · Cited by 178 · see citing works
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Blackburn, E. H., Epel, E. S., & Lin, J. (2015) · Science · doi:10.1126/science.aab3389 · Cited by 1,596 · see citing works
Jylhävä, J., Pedersen, N. L., & Hägg, S. (2017) · EBioMedicine · doi:10.1016/j.ebiom.2017.03.046 · Cited by 1,240 · see citing works
Self-citationTelomere Length and All-Cause Mortality: A Meta-analysis
Wang, Q., Zhan, Y., Pedersen, N. L., Fang, F., & Hägg, S. (2018) · Ageing Research Reviews · doi:10.1016/j.arr.2018.09.002 · Cited by 322 · see citing works
Self-citationMeta-analysis of Telomere Length in Alzheimer’s Disease
Forero, D. A., González-Giraldo, Y., López-Quintero, C., Castro-Vega, L. J., Barreto, G. E., & Perry, G. (2016) · The Journals of Gerontology Series A: Biological Sciences and Medical Sciences · doi:10.1093/gerona/glw053 · Cited by 229 · see citing works
Puterman, E., Gemmill, A., Karasek, D., Weir, D., Adler, N. E., Prather, A. A., & Epel, E. S. (2016) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1525602113 · Cited by 165 · see citing works
Genome-wide Association Analysis in Humans Links Nucleotide Metabolism to Leukocyte Telomere Length
Li, C., Stoma, S., Lotta, L. A., Warner, S. C., Albrecht, E., Allione, A., Arp, P., Broer, L., Buxton, J. L., Alves, A. C., et al. (2020) · The American Journal of Human Genetics · doi:10.1016/j.ajhg.2020.02.006 · Cited by 162 · see citing works
Self-citationStress, telomeres, and psychopathology: toward a deeper understanding of a triad of early aging
Epel, E. S., & Prather, A. A. (2018) · Annual Review of Clinical Psychology · doi:10.1146/annurev-clinpsy-032816-045054 · Cited by 153 · see citing works
Nutrition and the ageing brain: Moving towards clinical applications
Flanagan, E. C., Lamport, D. J., Brennan, L., Burnet, P. W. J., Calabrese, V., Cunnane, S. C., de Wilde, M. C., Dye, L., Farrimond, J. A., Lombardo, N. B. E., et al. (2020) · Ageing Research Reviews · doi:10.1016/j.arr.2020.101079 · Cited by 127 · see citing works
Wu, Z., Qu, J., & Liu, G.-H. (2024) · Nature Reviews Molecular Cell Biology · doi:10.1038/s41580-024-00775-3 · Cited by 118 · see citing works
Xu, X., Chen, X., Zhang, X., Liu, Y., Wang, Z., Wang, P., Du, Y., Qin, Y., & Chen, Z.-J. (2016) · Human Reproduction · doi:10.1093/humrep/dew283 · Cited by 109 · see citing works
Kuo, C., Pilling, L. C., Kuchel, G. A., Ferrucci, L., & Melzer, D. R. (2019) · Aging Cell · doi:10.1111/acel.13017 · Cited by 107 · see citing works
Rivero-Segura, N. A., Bello-Chavolla, O. Y., Barrera-Vázquez, O., Gutiérrez-Robledo, L., & Gómez-Verján, J. C. (2020) · Ageing Research Reviews · doi:10.1016/j.arr.2020.101164 · Cited by 76 · see citing works
The relationship between childhood psychosocial stressor level and telomere length: a meta-analysis
M. Hanssen, L., S. Schutte, N., M. Malouff, J., & S. Epel, E. (2017) · Health Psychology Research · doi:10.4081/hpr.2017.6378 · Cited by 93 · see citing works
“Telomere length appears to be one of the causal factors, as recent mendelian genetic studies of telomere length have shown direct prediction of earlier onset of certain diseases of aging (Codd et al., 2013; Zhan et al., 2015).”
BackgroundEpigenetic Mechanisms Impacting Aging: A Focus on Histone Levels and Telomeres
Song, S., & Johnson, F. B. (2018) · Genes · doi:10.3390/genes9040201 · Cited by 91 · see citing works
Farahzadi, R., Fathi, E., & Vietor, I. (2020) · ACS Chemical Neuroscience · doi:10.1021/acschemneuro.0c00052 · Cited by 91 · see citing works
Short telomere length is associated with impaired cognitive performance in European ancestry cohorts
Hägg, S., Zhan, Y., Karlsson, R., Gerritsen, L., Ploner, A., van der Lee, S. J., Broer, L., Deelen, J., Marioni, R. E., Wong, A., et al. (2017) · Translational Psychiatry · doi:10.1038/tp.2017.73 · Cited by 89 · see citing works
Self-citationWei, Z., Chen, X.-C., Song, Y., Pan, X.-D., Dai, X.-M., Zhang, J., Cui, X.-L., Wu, X.-L., & Zhu, Y.-G. (2016) · Chinese Medical Journal · doi:10.4103/0366-6999.186646 · Cited by 89 · see citing works
Innes, K. E., & Sambamoorthi, U. (2020) · Journal of Alzheimer s Disease · doi:10.3233/jad-200960 · Cited by 85 · see citing works
Park, S., Lee, S., Kim, Y., Cho, S., Kim, K., Kim, Y. C., Han, S. S., Lee, H., Lee, J. P., Joo, K. W., et al. (2021) · Kidney International · doi:10.1016/j.kint.2021.06.041 · Cited by 76 · see citing works
Biological Hallmarks of Cancer in Alzheimer’s Disease
Nudelman, K. N. H., McDonald, B. C., Lahiri, D. K., & Saykin, A. J. (2019) · Molecular Neurobiology · doi:10.1007/s12035-019-1591-5 · Cited by 72 · see citing works
Telomere Length and the Risk of Alzheimer’s Disease: The Rotterdam Study
Fani, L., Hilal, S., Sedaghat, S., Broer, L., Licher, S., Arp, P., van Meurs, J. B. J., Ikram, M. K., & Ikram, M. A. (2019) · Journal of Alzheimer s Disease · doi:10.3233/jad-190759 · Cited by 72 · see citing works
Telomere length and brain aging: A systematic review and meta-analysis
Gampawar, P. G., Schmidt, R., & Schmidt, H. (2022) · Ageing Research Reviews · doi:10.1016/j.arr.2022.101679 · Cited by 71 · see citing works
Machiela, M. J., Lan, Q., Slager, S. L., Vermeulen, R. C. H., Teras, L. R., Camp, N. J., Cerhan, J. R., Spinelli, J. J., Wang, S. S., Nieters, A., et al. (2016) · Human Molecular Genetics · doi:10.1093/hmg/ddw027 · Cited by 58 · see citing works
Developments in molecular epidemiology of aging
Hägg, S., Belsky, D. W., & Cohen, A. A. (2019) · Emerging Topics in Life Sciences · doi:10.1042/etls20180173 · Cited by 56 · see citing works
Self-citationKuźma, E., Hannon, E. J., Zhou, A., Lourida, I., Bethel, A. C., Levine, D. A., Lunnon, K., Coon, J. T., Hyppönen, E., & Llewellyn, D. J. (2018) · Journal of Alzheimer s Disease · doi:10.3233/jad-180013 · Cited by 59 · see citing works
Madrid, A. S., Rasmussen, K. L., Rode, L., Frikke‐Schmidt, R., Nordestgaard, B. G., & Bojesen, S. E. (2019) · European Journal of Epidemiology · doi:10.1007/s10654-019-00563-w · Cited by 54 · see citing works
Steptoe, A., Hamer, M., Lin, J., Blackburn, E. H., & Erusalimsky, J. D. (2016) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2016-3035 · Cited by 54 · see citing works
Drange, O. K., Smeland, O. B., Shadrin, A. A., Finseth, P. I., Witoelar, A., & Frei, O. (2019) · Frontiers in Neuroscience · doi:10.3389/fnins.2019.00220 · Cited by 53 · see citing works
Martens, D. S., & Nawrot, T. S. (2018) · Toxicology Letters · doi:10.1016/j.toxlet.2018.06.1213 · Cited by 47 · see citing works
Liu, B., Sun, Y., Xu, G., Snetselaar, L. G., Ludewig, G., Wallace, R. B., & Bao, W. (2018) · Journal of the Academy of Nutrition and Dietetics · doi:10.1016/j.jand.2018.09.007 · Cited by 47 · see citing works
Stress and Alzheimer’s disease: A senescence link?
Lyons, C. E., & Bartolomucci, A. (2020) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2020.05.010 · Cited by 47 · see citing works
Polygenic analysis of inflammatory disease variants and effects on microglia in the aging brain
Felsky, D., Patrick, E., Schneider, J. A., Mostafavi, S., Gaiteri, C., Patsopoulos, N. A., Bennett, D. A., & Jager, P. L. D. (2018) · Molecular Neurodegeneration · doi:10.1186/s13024-018-0272-6 · Cited by 44 · see citing works
Suelves, N., Saleki, S., Ibrahim, T., Palomares, D., Moonen, S., Koper, M. J., Vrancx, C., Vadukul, D. M., Papadopoulos, N., Viceconte, N., et al. (2023) · Acta Neuropathologica Communications · doi:10.1186/s40478-023-01578-x · Cited by 43 · see citing works
Huang, Y., Liu, L., Lo, K. K.-H., Huang, J., Zhang, B., & Feng, Y. (2020) · Annals of Translational Medicine · doi:10.21037/atm.2020.03.205 · Cited by 40 · see citing works
Zhou, X., Lian, P., Liu, H., Wang, Y., Zhou, M., & Feng, Z. (2023) · Nutrients · doi:10.3390/nu15204445 · Cited by 40 · see citing works
Zhan, Y., Clements, M., Roberts, R. O., Vassilaki, M. E., Druliner, B. R., Boardman, L. A., Petersen, R. C., Reynolds, C. A., Pedersen, N. L., & Hägg, S. (2018) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2018.05.004 · Cited by 37 · see citing works
Self-citationMason, A. E., Hecht, F. M., Daubenmier, J. J., Sbarra, D. A., Lin, J., Moran, P. J., Schleicher, S., Acree, M. C., Prather, A. A., & Epel, E. S. (2018) · Psychosomatic Medicine · doi:10.1097/psy.0000000000000616 · Cited by 38 · see citing works
A systematic review on the effects of social discrimination on telomere length
Coimbra, B. M., Carvalho, C. M., Ota, V., Vieira-Fonseca, T., Bugiga, A., Mello, A. F., Mello, M. F., & Belangero, S. I. (2020) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2020.104766 · Cited by 36 · see citing works
Hastings, W. J., Shalev, I., & Belsky, D. W. (2017) · Frontiers in Genetics · doi:10.3389/fgene.2017.00164 · Cited by 36 · see citing works
Cardillo, G. D. M., de Paula, V. D. J. R., Ikenaga, E. H., Costa, L. R., Catanozi, S., Schaeffer, E. L., Gattaz, W. F., Kerr, D. S., & Forlenza, O. V. (2018) · Journal of Alzheimer s Disease · doi:10.3233/jad-170838 · Cited by 35 · see citing works
Potential roles of telomeres and telomerase in neurodegenerative diseases
Wang, J., Liu, Y., Xia, Q., Xia, Q., Wang, B., Yang, C., Liang, J., & Liu, X. (2020) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2020.07.046 · Cited by 34 · see citing works
Liu, R., Xiang, M., Pilling, L. C., Melzer, D., Wang, L., Manning, K. J., Steffens, D. C., Bowden, J., Fortinsky, R. H., Kuchel, G. A., et al. (2023) · Aging Cell · doi:10.1111/acel.13808 · Cited by 33 · see citing works
Rodríguez‐Fernández, B., Vilor‐Tejedor, N., Arenaza‐Urquijo, E. M., Sánchez‐Benavides, G., Suárez‐Calvet, M., Operto, G., Minguillón, C., Fauria, K., Kollmorgen, G., Suridjan, I., et al. (2022) · Alzheimer s Research & Therapy · doi:10.1186/s13195-022-01101-9 · Cited by 31 · see citing works
Programmed ageing: decline of stem cell renewal, immunosenescence, and Alzheimer's disease
Lathe, R., & Clair, D. S. (2023) · Biological reviews/Biological reviews of the Cambridge Philosophical Society · doi:10.1111/brv.12959 · Cited by 36 · see citing works
An introduction to Mendelian randomization with applications in neurology
Allman, P., Aban, I., Tiwari, H. K., & Cutter, G. (2018) · Multiple Sclerosis and Related Disorders · doi:10.1016/j.msard.2018.06.017 · Cited by 33 · see citing works
Cao, W., Li, X., Zhang, X., Zhang, J., Sun, Q., Xu, X., Sun, M., Tian, Q., Li, Q., Wang, H., et al. (2019) · Cells · doi:10.3390/cells8020159 · Cited by 32 · see citing works
Gampawar, P. G., Schmidt, R., & Schmidt, H. (2020) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2020.00100 · Cited by 31 · see citing works
Hautekiet, P., Nawrot, T. S., Janssen, B. G., Martens, D. S., Clercq, E. M. D., Dadvand, P., Plusquin, M., Bijnens, E. M., & Saenen, N. D. (2020) · Environment International · doi:10.1016/j.envint.2020.106332 · Cited by 31 · see citing works
Hinterberger, M., Fischer, P., Huber, K., Krugluger, W., & Zehetmayer, S. (2017) · Journal of Neural Transmission · doi:10.1007/s00702-017-1721-z · Cited by 28 · see citing works
Gao, K., Chen, W., Zhu, J. L., Wang, X., Chen, G., Luo, Y., Zhang, D., Yue, W., & Yu, H. (2019) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2019.00843 · Cited by 29 · see citing works
Li, Z., Liu, H., Qian, Y., Li, X., Guo, C., Wang, Z., & Wei, Y. (2020) · Environment International · doi:10.1016/j.envint.2020.105769 · Cited by 29 · see citing works
Rodríguez‐Fernández, B., Gispert, J. D., Guigó, R., Navarro, A., Vilor‐Tejedor, N., & Crous‐Bou, M. (2022) · Computational and Structural Biotechnology Journal · doi:10.1016/j.csbj.2022.08.006 · Cited by 29 · see citing works
Leukocyte Telomere Length Shortening and Alzheimer’s Disease Etiology
Guo, Y., & Yu, H. (2019) · Journal of Alzheimer s Disease · doi:10.3233/jad-190134 · Cited by 27 · see citing works
de Baca, T. C., Prather, A. A., Lin, J., Sternfeld, B., Adler, N. E., Epel, E. S., & Puterman, E. M. (2019) · Molecular Psychiatry · doi:10.1038/s41380-019-0482-5 · Cited by 26 · see citing works
Zhan, Y., Liu, X., Reynolds, C. A., Pedersen, N. L., Hägg, S., & Clements, M. (2018) · American Journal of Epidemiology · doi:10.1093/aje/kwy128 · Cited by 25 · see citing works
Self-citationTelomere Shortening in the Alzheimer’s Disease Neuroimaging Initiative Cohort
Nudelman, K. N. H., Lin, J., Lane, K. A., Nho, K. T., Kim, S., Faber, K. M., Risacher, S. L., Foroud, T., Gao, S., Davis, J. W., et al. (2019) · Journal of Alzheimer s Disease · doi:10.3233/jad-190010 · Cited by 24 · see citing works
Rosero‐Bixby, L., Rehkopf, D. H., Dow, W. H., Lin, J., Epel, E. S., Azofeifa, J., & Leal, A. (2019) · PLoS ONE · doi:10.1371/journal.pone.0223766 · Cited by 24 · see citing works
Association Between Weight Change and Leukocyte Telomere Length in U.S. Adults
Zhang, Y., Xu, Z., Yang, Y., Cao, S., Lyu, S., & Duan, W. (2021) · Frontiers in Endocrinology · doi:10.3389/fendo.2021.650988 · Cited by 24 · see citing works
Fares, D. A., Schalekamp–Timmermans, S., Nawrot, T. S., & Steegers‐Theunissen, R. P. M. (2020) · Birth Defects Research · doi:10.1002/bdr2.1682 · Cited by 23 · see citing works
Genetically Predicted Telomere Length and Its Relationship With Alzheimer’s Disease
Yu, G., Lu, L., Ma, Z., & Wu, S. (2021) · Frontiers in Genetics · doi:10.3389/fgene.2021.595864 · Cited by 23 · see citing works
Stefler, D., Malyutina, S. K., Maximov, V. N., Orlov, P. S., Иванощук, Д. Е., Nikitin, Y., Гафаров, В. В., Ryabikov, A. N., Voevoda, M. I., Bobák, M., et al. (2018) · Scientific Reports · doi:10.1038/s41598-018-35122-y · Cited by 22 · see citing works
Dietary Copper Intake and Its Association With Telomere Length: A Population Based Study
Lin, Z., Gao, H., Wang, B., & Wang, Y. (2018) · Frontiers in Endocrinology · doi:10.3389/fendo.2018.00404 · Cited by 21 · see citing works
Genetically Determined Serum Uric Acid and Alzheimer’s Disease Risk
Yuan, H., & Yang, W. (2018) · Journal of Alzheimer s Disease · doi:10.3233/jad-180538 · Cited by 19 · see citing works
Inflammation and Vascular Ageing: From Telomeres to Novel Emerging Mechanisms
Chiriacò, M., Georgiopoulos, G. A., Duranti, E., Antonioli, L., Puxeddu, I., Nannipieri, M., Rosada, J., Blandizzi, C., Taddei, S., Virdis, A., et al. (2019) · High Blood Pressure & Cardiovascular Prevention · doi:10.1007/s40292-019-00331-7 · Cited by 19 · see citing works
Using Mendelian randomization to understand and develop treatments for neurodegenerative disease
Storm, C. S., Kia, D. A., Almramhi, M. M., & Wood, N. W. (2020) · Brain Communications · doi:10.1093/braincomms/fcaa031 · Cited by 19 · see citing works
Mahady, L. J., He, B., Malek‐Ahmadi, M. H., & Mufson, E. J. (2020) · Neuropathology and Applied Neurobiology · doi:10.1111/nan.12672 · Cited by 18 · see citing works
Crocco, P., Rango, F. D., Dato, S., Grotta, R. L., Maletta, R., Bruni, A. C., Passarino, G., & Rose, G. (2023) · Biology · doi:10.3390/biology12101286 · Cited by 15 · see citing works
Whither the genotype‐phenotype relationship? An historical and methodological appraisal
Fisch, G. S. (2017) · American Journal of Medical Genetics Part C Seminars in Medical Genetics · doi:10.1002/ajmg.c.31571 · Cited by 16 · see citing works
Amin, V., Fletcher, J. M., Sun, Z., & Lu, Q. (2021) · SSM - Population Health · doi:10.1016/j.ssmph.2021.101018 · Cited by 14 · see citing works
Incident hand OA is strongly associated with reduced peripheral blood leukocyte telomere length
McAlindon, T. E., Roberts, M. B., Driban, J. B., Schaefer, L. F., Haugen, I. K., Smith, S. E., Duryea, J., Cunha, D., Blanco, F. J., Fernández-García, J., et al. (2018) · Osteoarthritis and Cartilage · doi:10.1016/j.joca.2018.08.010 · Cited by 15 · see citing works
Fat metabolism is associated with telomere length in six population-based studies
van der Spek, A., Karamujić‐Čomić, H., Pool, R., Bot, M., Beekman, M., Garmaeva, S., Arp, P., Henkelman, S., Liu, J., Alves, A. C., et al. (2021) · Human Molecular Genetics · doi:10.1093/hmg/ddab281 · Cited by 16 · see citing works
Zhang, R., Zhao, J., Xu, J., & Liu, F. (2016) · Oncotarget · doi:10.18632/oncotarget.9536 · Cited by 14 · see citing works
Telomere length is independently associated with all-cause mortality in chronic heart failure
Romaine, S. P. R., Denniff, M. J., Codd, V., Nath, M., Koekemoer, A. L., Anker, S. D., Cleland, J. G. F., Filippatos, G. S., Levin, D., Metra, M., et al. (2021) · Heart · doi:10.1136/heartjnl-2020-318654 · Cited by 12 · see citing works
Aziz, N. A., & Weydt, P. (2018) · Journal of Neurology · doi:10.1007/s00415-018-8972-y · Cited by 11 · see citing works
Zhan, Y., & Hägg, S. (2018) · Methods in molecular biology · doi:10.1007/978-1-4939-7704-8_20 · Cited by 10 · see citing works
Self-citationDai, J., Xu, Y., Wang, T., & Zeng, P. (2022) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2022.110700 · Cited by 10 · see citing works
Uppuluri, L., Varapula, D. T., Young, E., Riethman, H. C., & Xiao, M. (2020) · Environmental Toxicology and Pharmacology · doi:10.1016/j.etap.2020.103562 · Cited by 10 · see citing works
Lin, A., Arnold, B. F., Mertens, A., Lin, J., Benjamin‐Chung, J., Ali, S., Hubbard, A., Stewart, C. P., Shoab, A. K., Rahman, M. Z., et al. (2017) · eLife · doi:10.7554/elife.29365 · Cited by 9 · see citing works
Haferkamp, U., Hartmann, C., Abid, C. L., Brachner, A., Höchner, A., Gerhartl, A., Harwardt, B., Leckzik, S., Leu, J., Metzger, M., et al. (2023) · Fluids and Barriers of the CNS · doi:10.1186/s12987-023-00471-y · Cited by 11 · see citing works
Early adversity and the comorbidity between metabolic disease and psychopathology
Gómez‐Ilescas, A., & Silveira, P. P. (2025) · The Journal of Physiology · doi:10.1113/jp285927 · Cited by 10 · see citing works
Lin, Z., Gao, H., Wang, B., & Wang, Y. (2021) · Mediators of Inflammation · doi:10.1155/2021/6675353 · Cited by 8 · see citing works
Gao, Y., Wang, T., Yu, X., Ferrari, R., Hernandez, D. G., Nalls, M. A., Rohrer, J. D., Ramasamy, A., Kwok, J. B., Dobson‐Stone, C., et al. (2020) · Scientific Reports · doi:10.1038/s41598-020-68848-9 · Cited by 7 · see citing works
Guo, X., Li, J., Qi, Y., Chen, J., Jiang, M., Zhu, L., Liu, Z., Wang, H., Wang, G.-W., & Wang, X. (2024) · Aging Cell · doi:10.1111/acel.14121 · Cited by 6 · see citing works
Palomares, D., Vanparys, A., Jorgji, J., Paître, E., Kienlen‐Campard, P., & Suelves, N. (2025) · Acta Neuropathologica Communications · doi:10.1186/s40478-025-02118-5 · Cited by 7 · see citing works
Li, W., Han, Y., Wang, P., & Qiao, S. (2025) · Alzheimer s & Dementia · doi:10.1002/alz.70803 · Cited by 6 · see citing works
Meng, X., Li, X., Cao, M., Dong, J., Wang, H., Cao, W., Liu, D., & Wang, Y. (2025) · Systematic Reviews · doi:10.1186/s13643-025-02792-5 · Cited by 5 · see citing works
Longer Telomere Length and its Association with Lower Levels of C-Peptide
Yang, M. J., Jiang, P. X., Jin, C., & Wang, J. (2017) · Frontiers in Endocrinology · doi:10.3389/fendo.2017.00244 · Cited by 5 · see citing works
Liang, Y., & Huang, P. (2023) · Aging Clinical and Experimental Research · doi:10.1007/s40520-023-02607-4 · Cited by 4 · see citing works
Bayón, A. R., & Sampedro, F. G. (2018) · Neurología (English Edition) · doi:10.1016/j.nrleng.2017.01.011 · Cited by 4 · see citing works
Fernández‐Eulate, G., Alberro, A., Muñoz‐Culla, M., Zulaica, M., Zufiría, M., Barandiarán, M., Etxeberría, I., Yanguas, J. J., Gallardo, M. M., Soberón, N. E., et al. (2018) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2018.00380 · Cited by 3 · see citing works
Wang, Y., Liu, Q., Liang, S., Yao, M., Zheng, H., Hu, D., & Wang, Y. (2024) · Aging · doi:10.18632/aging.205583 · Cited by 3 · see citing works
The relationship between naevus count, memory function and telomere length in the Twins UK cohort
Masi, S., Georgiopoulos, G. A., Ribero, S., Taddei, S., Bataille, V. A., & Steves, C. J. (2018) · Pigment Cell & Melanoma Research · doi:10.1111/pcmr.12722 · Cited by 2 · see citing works
Combining Mendelian randomization with the sibling comparison design
Sjölander, A., Frisell, T., Öberg, A. S., Wang, Y., & Hägg, S. (2023) · Statistics in Medicine · doi:10.1002/sim.9983 · Cited by 2 · see citing works
Self-citationBarbé‐Tuana, F. M., Grün, L. K., Pierdoná, V., de Oliveira, B. C. D., de Paiva, S. C., Shiburah, M. E., da Silva, V. L., Morea, E. G. O., Fontes, V. S., & Cano, M. I. N. (2021) · Springer eBooks · doi:10.1007/978-3-030-73151-9_7 · Cited by 2 · see citing works
Longueur des télomères : de la sénescence cellulaire aux trajectoires du vieillissement humain
Benetos, A. (2022) · Bulletin de l Académie Nationale de Médecine · doi:10.1016/j.banm.2022.02.018 · Cited by 2 · see citing works
Editorial: Genetics of Age-Related Diseases and Their Risk and Protective Factors
Karlsson, I., Arpawong, T. E., Zhan, Y., & Lehto, K. (2021) · Frontiers in Genetics · doi:10.3389/fgene.2021.771109 · Cited by 2 · see citing works
Self-citationTelomere Dynamics and Aging Related Diseases
Toupance, S., & Bénétos, A. (2019) · Cambridge University Press eBooks · doi:10.1017/9781316677018.007 · Cited by 1 · see citing works
Association of Telomere Length, a Cellular Aging Marker, with Depression, PTSD and Hostility
Zhang, L., Hu, X., Li, X., Dohl, J., Yu, T., & Ursano, R. J. (2019) · OBM Geriatrics · doi:10.21926/obm.geriatr.1901041 · Cited by 1 · see citing works
Campos-Sánchez, I., Navarrete‐Muñoz, E. M., Martens, D. S., Galán, I. R., Lertxundi, A., Llop, S., Guxens, M., Rodríguez-Dehli, C., Lertxundi, N., Soler-Blasco, R., et al. (2025) · Journal of Attention Disorders · doi:10.1177/10870547251314923 · Cited by 1 · see citing works
The telomere-telomerase system and mental processes in aging, norm and pathology (Literature review)
Pavlov, K. I., Mukhin, V. N., Клименко, В. М., & Anisimov, V. N. (2017) · Advances in Gerontology · doi:10.1134/s2079057017020114 · Cited by 14 · see citing works
- Authors
- Zhan, Y., Song, C., Karlsson, R., Tillander, A., Reynolds, C. A., Pedersen, N. L., & Hägg, S.
- Affiliations
- Karolinska Institutet (SE)
- University of California, Riverside (US)
- Corresponding author
- Hägg, Sara
- ORCID
- Venue
- JAMA Neurology
- Publisher
- American Medical Association (AMA)
- Published
- 2015-10-01
- Volume
- 72
- Issue
- 10
- Pages
- 1202
- ISSN
- 2168-6149 (ISSN-L)
- OpenAlex
- W2122450728
- Cited by
- 111
- References
- 6
- Citations by year
- 2025: 7 · 2024: 4 · 2023: 8 · 2022: 6 · 2021: 9 · 2020: 18 · 2019: 18 · 2018: 23 · 2017: 10 · 2016: 7 · 2015: 1
- FWCI
- 11.14
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- JAMA Neurology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Psychiatry and Mental health › Dementia and Cognitive Impairment Research
- Health Sciences › Medicine › Physiology › Telomeres, Telomerase, and Senescence
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Genetic Associations and Epidemiology
- Keywords
- telomere length, telomere shortening, Alzheimer's disease, genetic variants, causal inference
- MeSH terms
- Alzheimer Disease, Genetic Testing, Humans, Risk, Telomere, Polymorphism, Single Nucleotide, Mendelian Randomization Analysis
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