Cross‐over Trials In Clinical Research
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The study used a double-blind, placebo-controlled, cross-over design with baseline measurements before each treatment.
“We adopted a double‐blind AB/BA (oxytocin‐placebo/placebo‐oxytocin) cross‐over design with baseline measurements before each treatment 49 to test for treatment effects.”
From The Analgesic Effect of Oxytocin in Humans: A Double‐Blind, Placebo‐Controlled Cross‐Over Study Using Laser‐Evoked Potentials (2016) · cites this paper as [49]
Treatment effects were tested using an ANCOVA approach for AB/BA cross-over designs with baseline measurements before each treatment.
“We tested for treatment effects (oxytocin versus placebo) using the analysis of covariance (ancova) approach described by Senn 49 and Metcalfe 56 for the analysis of AB/BA cross‐over designs with baseline measurements before each treatment.”
From The Analgesic Effect of Oxytocin in Humans: A Double‐Blind, Placebo‐Controlled Cross‐Over Study Using Laser‐Evoked Potentials (2016) · cites this paper as [49]
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- Authors
- Senn, S.
- Corresponding author
- Senn, Stephen
- ORCID
- Senn, Stephen
- Venue
- Wiley eBooks
- Publisher
- Wiley
- Published
- 2002-07-15
- OpenAlex
- W4229753260
- Cited by
- 653
- References
- 0
- Citations by year
- 2026: 32 · 2025: 28 · 2024: 33 · 2023: 35 · 2022: 33 · 2021: 40 · 2020: 36 · 2019: 32 · 2018: 32 · 2017: 32 · 2016: 24 · 2015: 42 · 2014: 35 · 2013: 29 · 2012: 29
- FWCI
- 2.95
- Type
- book
- Language
- en
- Open access
- closed
- Locations
- Wiley eBooks (publishedVersion)
- Topics
- Physical Sciences › Mathematics › Statistics and Probability › Statistical Methods in Clinical Trials
- Social Sciences › Decision Sciences › Management Science and Operations Research › Optimal Experimental Design Methods
- Physical Sciences › Mathematics › Statistics and Probability › Statistical Methods and Bayesian Inference
- Keywords
- crossover trial, clinical trials, treatment comparison
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
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