Isolation and Characterization of Exosomes from Cell Culture Supernatants and Biological Fluids

B lymphocytes secrete antigen-presenting vesicles.

Raposo, G., Nijman, H. W., Stoorvogel, W., Liejendekker, R., Harding, C. V., Melief, C. J., & Geuze, H. J. (1996) · The Journal of experimental medicine · doi:10.1084/jem.183.3.1161 · Cited by 3,546

Eradication of established murine tumors using a novel cell-free vaccine: dendritic cell derived exosomes

Zitvogel, L., Régnault, A., Lozier, A., Wolfers, J., Flament, C., Tenza, D., Ricciardi‐Castagnoli, P., Raposo, G., & Amigorena, S. (1998) · Nature Medicine · doi:10.1038/nm0598-594 · Cited by 2,266

Identification and proteomic profiling of exosomes in human urine

Pisitkun, T., Shen, R., & Knepper, M. A. (2004) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0403453101 · Cited by 2,162

Tumor-derived exosomes are a source of shared tumor rejection antigens for CTL cross-priming

Wolfers, J., Lozier, A., Raposo, G., Régnault, A., Théry, C., Masurier, C., Flament, C., Pouzieux, S., Faure, F., Tursz, T., et al. (2001) · Nature Medicine · doi:10.1038/85438 · Cited by 1,643

Proteomic Analysis of Dendritic Cell-Derived Exosomes: A Secreted Subcellular Compartment Distinct from Apoptotic Vesicles

Théry, C., Boussac, M., Véron, P., Ricciardi‐Castagnoli, P., Raposo, G., Garin, J., & Amigorena, S. (2001) · The Journal of Immunology · doi:10.4049/jimmunol.166.12.7309 · Cited by 1,564

Activated Platelets Release Two Types of Membrane Vesicles: Microvesicles by Surface Shedding and Exosomes Derived From Exocytosis of Multivesicular Bodies and -Granules

Heijnen, H. F. G., Schiel, A. E., Fijnheer, R., Geuze, H. J., & Sixma, J. J. (1999) · Blood · doi:10.1182/blood.v94.11.3791 · Cited by 1,488

Exosomal-like vesicles are present in human blood plasma

Caby, M.-P., Lankar, D., Vincendeau-Scherrer, C., Raposo, G., & Bonnerot, C. (2005) · International Immunology · doi:10.1093/intimm/dxh267 · Cited by 1,348

Electron microscopic evidence for externalization of the transferrin receptor in vesicular form in sheep reticulocytes.

Pan, B., Teng, K., Wu, C., Adam, M., & Johnstone, R. M. (1985) · The Journal of Cell Biology · doi:10.1083/jcb.101.3.942 · Cited by 1,242

Selective Enrichment of Tetraspan Proteins on the Internal Vesicles of Multivesicular Endosomes and on Exosomes Secreted by Human B-lymphocytes

Escola, J.-M., Kleijmeer, M. J., Stoorvogel, W., Griffith, J. M., Yoshie, O., & Geuze, H. J. (1998) · Journal of Biological Chemistry · doi:10.1074/jbc.273.32.20121 · Cited by 1,228

Molecular Characterization of Dendritic Cell-Derived Exosomes

Théry, C., Régnault, A., Garin, J., Wolfers, J., Zitvogel, L., Ricciardi‐Castagnoli, P., Raposo, G., & Amigorena, S. (1999) · The Journal of Cell Biology · doi:10.1083/jcb.147.3.599 · Cited by 1,065

Glioblastoma‐derived extracellular vesicles modify the phenotype of monocytic cells

de Vrij, J., Maas, S. L. N., Kwappenberg, K. M. C., Schnoor, R., Kleijn, A., Dekker, L. J. M., Luider, T. M., de Witte, L. D., Litjens, M., van Strien, M. E., et al. (2015) · International Journal of Cancer · doi:10.1002/ijc.29521 · Cited by 198

Exosomes of human placenta-derived mesenchymal stem cells stimulate angiogenesis

Komaki, M., Numata, Y., Morioka, C., Honda, I., Tooi, M., Yokoyama, N., Ayame, H., Iwasaki, K., Taki, A., Oshima, N., et al. (2017) · Stem Cell Research & Therapy · doi:10.1186/s13287-017-0660-9 · Cited by 203

Exosomal delivery of doxorubicin enables rapid cell entry and enhanced in vitro potency

Schindler, C., Collinson, A., Matthews, C., Pointon, A., Jenkinson, L., Minter, R., Vaughan, T. J., & Tigue, N. J. (2019) · PLoS ONE · doi:10.1371/journal.pone.0214545 · Cited by 205

Magnetic resonance imaging of melanoma exosomes in lymph nodes

Hu, L., Wickline, S. A., & Hood, J. L. (2014) · Magnetic Resonance in Medicine · doi:10.1002/mrm.25376 · Cited by 199

ExoAPP: Exosome-Oriented, Aptamer Nanoprobe-Enabled Surface Proteins Profiling and Detection

Jin, D., Yang, F., Zhang, Y., Liu, L., Zhou, Y., Wang, F., & Zhang, G. (2018) · Analytical Chemistry · doi:10.1021/acs.analchem.8b03959 · Cited by 198

Advanced liquid biopsy technologies for circulating biomarker detection

Soda, N., Rehm, B. H. A., Sonar, P. M., Nguyen, N., & Shiddiky, M. J. A. (2019) · Journal of Materials Chemistry B · doi:10.1039/c9tb01490j · Cited by 205

Gap junctional protein Cx43 is involved in the communication between extracellular vesicles and mammalian cells

Soares, A. R., Martins‐Marques, T., Ribeiro‐Rodrigues, T., Ferreira, J. V., Catarino, S., Pinho, M. J., Zuzarte, M., Anjo, S. I., Manadas, B. J., Sluijter, J. P. G., et al. (2015) · Scientific Reports · doi:10.1038/srep13243 · Cited by 200

Loss of the Timp gene family is sufficient for the acquisition of the CAF-like cell state

Shimoda, M., Principe, S., Jackson, H. W., Luga, V., Fang, H., Molyneux, S. D., Shao, Y. W., Aiken, A., Waterhouse, P. D., Karamboulas, C., et al. (2014) · Nature Cell Biology · doi:10.1038/ncb3021 · Cited by 209

MicroRNA-15a and MicroRNA-16 Impair Human Circulating Proangiogenic Cell Functions and Are Increased in the Proangiogenic Cells and Serum of Patients With Critical Limb Ischemia

Spinetti, G., Fortunato, O., Caporali, A., Shantikumar, S., Marchetti, M., Meloni, M., Descamps, B., Floris, I., Sangalli, E., Vono, R., et al. (2012) · Circulation Research · doi:10.1161/circresaha.111.300418 · Cited by 198

Method for isolation and molecular characterization of extracellular microvesicles released from brain endothelial cells

Haqqani, A. S., Delaney, C. E., Tremblay, T., Sodja, C., Sandhu, J. K., & Stanimirovic, D. B. (2013) · Fluids and Barriers of the CNS · doi:10.1186/2045-8118-10-4 · Cited by 200

Salivary Biomarkers for Oral Squamous Cell Carcinoma Diagnosis and Follow-Up: Current Status and Perspectives

Cristaldi, M., Mauceri, R., Fede, O. D., Giuliana, G., Campisi, G., & Panzarella, V. (2019) · Frontiers in Physiology · doi:10.3389/fphys.2019.01476 · Cited by 202

Isolation of Extracellular Vesicles by Ultracentrifugation

Momen‐Heravi, F. (2017) · Methods in molecular biology · doi:10.1007/978-1-4939-7253-1_3 · Cited by 207

LAMP2A regulates the loading of proteins into exosomes

Ferreira, J. V., Soares, A. D. R., Ramalho, J. S., Carvalho, C. M., Cardoso, M. H., Pintado, P. A., Carvalho, A. S., Beck, H. C., Matthiesen, R., Zuzarte, M., et al. (2022) · Science Advances · doi:10.1126/sciadv.abm1140 · Cited by 201

Human-to-mouse prion-like propagation of mutant huntingtin protein

Jeon, I., Cicchetti, F., Cisbani, G., Lee, S., Li, E., Bae, J., Lee, N., Li, L., Im, W., Kim, M., et al. (2016) · Acta Neuropathologica · doi:10.1007/s00401-016-1582-9 · Cited by 197

Inclusion Biogenesis, Methods of Isolation and Clinical Application of Human Cellular Exosomes

Tschuschke, M., Kocherova, I., Bryja, A., Mozdziak, P. E., Volponi, A. A., Janowicz, K., Sibiak, R., Piotrowska‐Kempisty, H., Iżycki, D., Bukowska, D., et al. (2020) · Journal of Clinical Medicine · doi:10.3390/jcm9020436 · Cited by 205

A scaffold laden with mesenchymal stem cell-derived exosomes for promoting endometrium regeneration and fertility restoration through macrophage immunomodulation

Xin, L., Lin, X., Zhou, F., Li, C., Wang, X., Yu, H., Pan, Y., Fei, H., Ma, L., & Zhang, S. (2020) · Acta Biomaterialia · doi:10.1016/j.actbio.2020.06.029 · Cited by 202

Characterization of Regulatory Extracellular Vesicles from Osteoclasts

Huynh, N., VonMoss, L., Smith, D., Rahman, I., Felemban, M. F., Zuo, J., Rody, W. J., McHugh, K. P., & Holliday, L. S. (2016) · Journal of Dental Research · doi:10.1177/0022034516633189 · Cited by 196

On-chip surface acoustic wave lysis and ion-exchange nanomembrane detection of exosomal RNA for pancreatic cancer study and diagnosis

Taller, D., Richards, K. E., Slouka, Z., Senapati, S., Hill, R., Go, D. B., & Chang, H. (2015) · Lab on a Chip · doi:10.1039/c5lc00036j · Cited by 195

Microfluidics‐based on‐a‐chip systems for isolating and analysing extracellular vesicles

Guo, S., Tao, S., & Dawn, H. (2018) · Journal of Extracellular Vesicles · doi:10.1080/20013078.2018.1508271 · Cited by 206

Exosomes From Human Cardiac Progenitor Cells for Therapeutic Applications: Development of a GMP-Grade Manufacturing Method

Andriolo, G., Provasi, E., Cicero, V. L., Brambilla, A., Soncin, S., Torre, T., Milano, G., Biemmi, V., Vassalli, G., Turchetto, L., et al. (2018) · Frontiers in Physiology · doi:10.3389/fphys.2018.01169 · Cited by 195

Integrated nanoscale deterministic lateral displacement arrays for separation of extracellular vesicles from clinically-relevant volumes of biological samples

Smith, J. T., Wunsch, B. H., Dogra, N., Ahsen, M. E., Lee, K., Yadav, K. K., Weil, R., Pereira, M. A., Patel, J. V., Duch, E. A., et al. (2018) · Lab on a Chip · doi:10.1039/c8lc01017j · Cited by 195

Direct isolation and characterization of circulating exosomes from biological samples using magnetic nanowires

Lim, J., Choi, M., Lee, H., Kim, Y.-H., Han, J., Lee, E. S., & Cho, Y. (2019) · Journal of Nanobiotechnology · doi:10.1186/s12951-018-0433-3 · Cited by 195

Effective methods for isolation and purification of extracellular vesicles from plants

Huang, Y., Wang, S., Cai, Q., & Jin, H. (2021) · Journal of Integrative Plant Biology · doi:10.1111/jipb.13181 · Cited by 199

Manufacturing Therapeutic Exosomes: from Bench to Industry

Ahn, S., Ryu, S.-W., Choi, H., You, S., Park, J., & Choi, C. (2022) · Molecules and Cells · doi:10.14348/molcells.2022.2033 · Cited by 204

Interferometric plasmonic imaging and detection of single exosomes

Yang, Y., Shen, G., Wang, H., Li, H., Zhang, T., Tao, N. J., Ding, X., & Yu, H. (2018) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1804548115 · Cited by 191

Human Saliva-Derived Exosomes

Zlotogorski‐Hurvitz, A., Dayan, D., Chaushu, G., Korvala, J., Salo, T. A., Sormunen, R. T., & Vered, M. (2014) · Journal of Histochemistry & Cytochemistry · doi:10.1369/0022155414564219 · Cited by 197

Size‐exclusion chromatography as a stand‐alone methodology identifies novel markers in mass spectrometry analyses of plasma‐derived vesicles from healthy individuals

Menezes‐Neto, A., Sáez, M. J. F., Lozano‐Ramos, I., Seguí-Barber, J., Jaular, L. M., Estanyol, J. M., Fernández-Becerra, C., Borràs, F. E., & Portillo, H. A. D. (2015) · Journal of Extracellular Vesicles · doi:10.3402/jev.v4.27378 · Cited by 193

Primary Human and Rat β-Cells Release the Intracellular Autoantigens GAD65, IA-2, and Proinsulin in Exosomes Together With Cytokine-Induced Enhancers of Immunity

Cianciaruso, C., Phelps, E. A., Pasquier, M. C., Hamelin, R., Demurtas, D., Ahmed, M. A., Piemonti, L., Hirosue, S., Swartz, M. A., Palma, M. D., et al. (2016) · Diabetes · doi:10.2337/db16-0671 · Cited by 193

Comparative analysis of EV isolation procedures for miRNAs detection in serum samples

Andreu, Z., Rivas, E., Sanguino-Pascual, A., Lamana, A., Marazuela, M., González‐Álvaro, I., Sánchez‐Madrid, F., de la Fuente, H., & Yáñez‐Mó, M. (2016) · Journal of Extracellular Vesicles · doi:10.3402/jev.v5.31655 · Cited by 196

Focus on Mesenchymal Stem Cell-Derived Exosomes: Opportunities and Challenges in Cell-Free Therapy

Cheng, L., Zhang, K., Wu, S., Cui, M., & Xu, T. (2017) · Stem Cells International · doi:10.1155/2017/6305295 · Cited by 196

Salivary Exosomes: Emerging Roles in Systemic Disease

Han, Y., Jia, L., Zheng, Y., & Li, W. (2018) · International Journal of Biological Sciences · doi:10.7150/ijbs.25018 · Cited by 196

Magnetic Bead-Based Isolation of Exosomes

Oksvold, M. P., Neurauter, A. A., & Pedersen, K. W. (2014) · Methods in molecular biology · doi:10.1007/978-1-4939-1538-5_27 · Cited by 192

Heparin affinity purification of extracellular vesicles

Balaj, L., Atai, N. A., Chen, W., Mu, D., Tannous, B. A., Breakefield, X. O., Skog, J., & Maguire, C. A. (2015) · Scientific Reports · doi:10.1038/srep10266 · Cited by 204

Exosomes Derived from Human Bone Marrow Mesenchymal Stem Cells Promote Tumor Growth Through Hedgehog Signaling Pathway

Qi, J., Zhou, Y., Jiao, Z., Wang, X., Zhao, Y., Li, Y., Chen, H., Yang, L., Zhu, H., & Li, Y. (2017) · Cellular Physiology and Biochemistry · doi:10.1159/000479998 · Cited by 191

Cushioned–Density Gradient Ultracentrifugation (C-DGUC): A Refined and High Performance Method for the Isolation, Characterization, and Use of Exosomes

Li, K., Wong, D., Hong, K. Y., & Raffaı̈, R. L. (2018) · Methods in molecular biology · doi:10.1007/978-1-4939-7652-2_7 · Cited by 191

Extracellular Vesicle-Educated Macrophages Promote Early Achilles Tendon Healing

Chamberlain, C. S., Clements, A. E. B., Kink, J. A., Choi, U., Baer, G. S., Halanski, M. A., Hematti, P., & Vanderby, R. (2019) · Stem Cells · doi:10.1002/stem.2988 · Cited by 193

Immunomodulatory molecules are released from the first trimester and term placenta via exosomes

Kshirsagar, S., Alam, S. M. K., Jasti, S., Hodes, H., Nauser, T., Gilliam, M. L., Billstrand, C., Hunt, J. S., & Petroff, M. G. (2012) · Placenta · doi:10.1016/j.placenta.2012.10.005 · Cited by 190

Mechanism of TNF-α autocrine effects in hypoxic cardiomyocytes: Initiated by hypoxia inducible factor 1α, presented by exosomes

Yu, X., Deng, L., Wang, D., Li, N., Chen, X., Cheng, X. C., Jin, Y., Gao, X., Liao, M., Wang, M., et al. (2012) · Journal of Molecular and Cellular Cardiology · doi:10.1016/j.yjmcc.2012.10.002 · Cited by 190

Extracellular vesicles from human embryonic stem cell-derived cardiovascular progenitor cells promote cardiac infarct healing through reducing cardiomyocyte death and promoting angiogenesis

Wu, Q., Wang, J., Tan, W. L. W., Jiang, Y. Y., Wang, S., Li, Q., Yu, X., Tan, J., Liu, S., Zhang, P., et al. (2020) · Cell Death and Disease · doi:10.1038/s41419-020-2508-y · Cited by 191

Mesenchymal stem/stromal cell-derived exosomes in regenerative medicine and cancer; overview of development, challenges, and opportunities

Hassanzadeh, A., Rahman, H. S., Markov, A. A., Endjun, J. J., Zekiy, A. O., Chartrand, M. S., Beheshtkhoo, N., Kouhbanani, M. A. J., Marofi, F., Nikoo, M., et al. (2021) · Stem Cell Research & Therapy · doi:10.1186/s13287-021-02378-7 · Cited by 198

Mechanically induced Ca2+ oscillations in osteocytes release extracellular vesicles and enhance bone formation

Morrell, A. E., Brown, G. N., Robinson, S. T., Sattler, R. L., Baik, A. D., Zhen, G., Cao, X., Bonewald, L. F., Jin, W., Kam, L. C., et al. (2018) · Bone Research · doi:10.1038/s41413-018-0007-x · Cited by 184

Hypoxia-Induced Changes in the Bioactivity of Cytotrophoblast-Derived Exosomes

Salomón, C., Kobayashi, M., Ashman, K., Sobrevía, L., Mitchell, M. D., & Rice, G. E. (2013) · PLoS ONE · doi:10.1371/journal.pone.0079636 · Cited by 188

TNF-Related Apoptosis-Inducing Ligand (TRAIL)–Armed Exosomes Deliver Proapoptotic Signals to Tumor Site

Rivoltini, L., Chiodoni, C., Squarcina, P., Tortoreto, M., Villa, A., Vergani, B., Bürdek, M., Botti, L., Arioli, I., Cova, A., et al. (2016) · Clinical Cancer Research · doi:10.1158/1078-0432.ccr-15-2170 · Cited by 178

“Exosomics”—A Review of Biophysics, Biology and Biochemistry of Exosomes With a Focus on Human Breast Milk

de la Torre, C., Goreham, R. V., Bech‐Serra, J. J., Nann, T., & Kussmann, M. (2018) · Frontiers in Genetics · doi:10.3389/fgene.2018.00092 · Cited by 196

Rapid isolation and enrichment of extracellular vesicle preparations using anion exchange chromatography

Heath, N., Grant, L. R., de Oliveira, T. M., Rowlinson, R. A., Osteikoetxea, X., Dekker, N., & Overman, R. (2018) · Scientific Reports · doi:10.1038/s41598-018-24163-y · Cited by 198

The immunostimulatory RNA RN7SL1 enables CAR-T cells to enhance autonomous and endogenous immune function

Johnson, L. R., Lee, D. Y., Eacret, J. S., Ye, D., June, C. H., & Minn, A. J. (2021) · Cell · doi:10.1016/j.cell.2021.08.004 · Cited by 190

Extracellular vesicle analysis

Hendrix, A., Lippens, L., Pinheiro, C., Théry, C., Jaular, L. M., Lötvall, J. O., Lässer, C., Hill, A. F., & Witwer, K. W. (2023) · Nature Reviews Methods Primers · doi:10.1038/s43586-023-00240-z · Cited by 197

Proteolipidic Composition of Exosomes Changes during Reticulocyte Maturation

Carayon, K., Chaoui, K., Ronzier, E., Lazar, I., Bertrand‐Michel, J., Roques, V., Balor, S., Tercé, F., Lopez, A., Salomé, L., et al. (2011) · Journal of Biological Chemistry · doi:10.1074/jbc.m111.257444 · Cited by 196

Effect of extracellular vesicles of human adipose tissue on insulin signaling in liver and muscle cells

Kranendonk, M. E. G., Visseren, F. L. J., van Herwaarden, J. A., Hoen, E. N. M. N., de Jager, W., Wauben, M. H. M., & Kalkhoven, E. (2014) · Obesity · doi:10.1002/oby.20847 · Cited by 195

Roles of exosomes in the normal and diseased eye

Klingeborn, M., Dismuke, W. M., Rickman, C. B., & Stamer, W. D. (2017) · Progress in Retinal and Eye Research · doi:10.1016/j.preteyeres.2017.04.004 · Cited by 186

Extracellular vesicles derived from MSCs activates dermal papilla cell in vitro and promotes hair follicle conversion from telogen to anagen in mice

Rajendran, R. L., Gangadaran, P., Bak, S., Oh, J. M., Kalimuthu, S., Lee, H., Baek, S. H., Zhu, L., Sung, Y. K., Jeong, S. Y., et al. (2017) · Scientific Reports · doi:10.1038/s41598-017-15505-3 · Cited by 196

Human Umbilical Cord MSC-Derived Exosomes Suppress the Development of CCl 4 -Induced Liver Injury through Antioxidant Effect

Jiang, W., Tan, Y., Cai, M., Zhao, T., Mao, F., Zhang, X., Xu, W., Yan, Z., Qian, H., & Yan, Y. (2018) · Stem Cells International · doi:10.1155/2018/6079642 · Cited by 188

The Fas/Fap-1/Cav-1 complex regulates IL-1RA secretion in mesenchymal stem cells to accelerate wound healing

Kou, X., Xu, X., Chen, C., Sanmillan, M. L., Cai, T., Zhou, Y., Giraudo, C. G., Le, A. D., & Shi, S. (2018) · Science Translational Medicine · doi:10.1126/scitranslmed.aai8524 · Cited by 191

The Aerobic and Cognitive Exercise Study (ACES) for Community-Dwelling Older Adults With or At-Risk for Mild Cognitive Impairment (MCI): Neuropsychological, Neurobiological and Neuroimaging Outcomes of a Randomized Clinical Trial

Anderson‐Hanley, C., Barcelos, N. M., Zimmerman, E. A., Gillen, R. W., Dunnam, M., Cohen, B. D., Yerokhin, V., Miller, K. E., Hayes, D. J., Arciero, P. J., et al. (2018) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2018.00076 · Cited by 194

Human umbilical cord mesenchymal stem cell‐derived extracellular vesicles: A novel therapeutic paradigm

Abbaszadeh, H., Ghorbani, F., Derakhshani, M., Movassaghpour, A., & Yousefi, M. (2020) · Journal of Cellular Physiology · doi:10.1002/jcp.29004 · Cited by 188

Exosome: a significant nano-scale drug delivery carrier

Peng, H., Ji, W., Zhao, R., Yang, J., Lü, Z., Li, Y., & Zhang, X. (2020) · Journal of Materials Chemistry B · doi:10.1039/d0tb01499k · Cited by 192

Extracellular Vesicles and Exosomes: Insights From Exercise Science

Nederveen, J. P., Warnier, G., Carlo, A. D., Nilsson, M. I., & Tarnopolsky, M. A. (2021) · Frontiers in Physiology · doi:10.3389/fphys.2020.604274 · Cited by 200

Exosomes neutralize synaptic-plasticity-disrupting activity of Aβ assemblies in vivo

An, K., Klyubin, I. V., Kim, Y., Jung, J. H., Mably, A. J., O’Dowd, S., Lynch, T., Kanmert, D., Lemere, C. A., Finan, G. M., et al. (2013) · Molecular Brain · doi:10.1186/1756-6606-6-47 · Cited by 196

Therapeutic and diagnostic applications of extracellular vesicles

Stremersch, S., Smedt, S. C. D., & Raemdonck, K. (2016) · Journal of Controlled Release · doi:10.1016/j.jconrel.2016.07.054 · Cited by 189

Nanosomes carrying doxorubicin exhibit potent anticancer activity against human lung cancer cells

Srivastava, A., Amreddy, N., Babu, A., Panneerselvam, J., Mehta, M., Muralidharan, R., Chen, A., Zhao, Y. D., Razaq, M., Riedinger, N., et al. (2016) · Scientific Reports · doi:10.1038/srep38541 · Cited by 192

Exosomes originating from MSCs stimulated with TGF‐β and IFN‐γ promote Treg differentiation

Zhang, Q., Fu, L. N., Liang, Y., Guo, Z., Wang, L., Ma, C., & Wang, H. (2018) · Journal of Cellular Physiology · doi:10.1002/jcp.26436 · Cited by 193

Early gestational mesenchymal stem cell secretome attenuates experimental bronchopulmonary dysplasia in part via exosome-associated factor TSG-6

Chaubey, S., Thueson, S., Ponnalagu, D., Alam, M. A., Gheorghe, C. P., Aghai, Z. H., Singh, H., & Bhandari, V. (2018) · Stem Cell Research & Therapy · doi:10.1186/s13287-018-0903-4 · Cited by 188

Senescence cell–associated extracellular vesicles serve as osteoarthritis disease and therapeutic markers

Jeon, O. H., Wilson, D. R., Clement, C. C., Rathod, S., Cherry, C., Powell, B. H., Lee, Z., Khalil, A. M., Green, J. J., Campisi, J., et al. (2019) · JCI Insight · doi:10.1172/jci.insight.125019 · Cited by 190

Tubular epithelial cell-to-macrophage communication forms a negative feedback loop via extracellular vesicle transfer to promote renal inflammation and apoptosis in diabetic nephropathy

Jiang, W., Xu, C., Du, C., Dong, J., Xu, S., Hu, B.-F., Feng, R., Zang, D., Meng, X., Huang, C., et al. (2021) · Theranostics · doi:10.7150/thno.63735 · Cited by 188

Exosomes as bio-inspired nanocarriers for RNA delivery: preparation and applications

Amiri, A., Bagherifar, R., Ansari Dezfouli, E., Kiaie, S. H., Jafari, R., & Ramezani, R. (2022) · Journal of Translational Medicine · doi:10.1186/s12967-022-03325-7 · Cited by 186

Urinary extracellular vesicles and the kidney: biomarkers and beyond

Salih, M., Zietse, R., & Hoorn, E. J. (2014) · American Journal of Physiology-Renal Physiology · doi:10.1152/ajprenal.00128.2014 · Cited by 193

Detailed Analysis of Protein Topology of Extracellular Vesicles–Evidence of Unconventional Membrane Protein Orientation

Cvjetkovic, A., Jang, S. C., Konečná, B., Höög, J. L., Sihlbom, C., Lässer, C., & Lötvall, J. O. (2016) · Scientific Reports · doi:10.1038/srep36338 · Cited by 185

Augmented liver targeting of exosomes by surface modification with cationized pullulan

Tamura, R., Üemoto, S., & Tabata, Y. (2017) · Acta Biomaterialia · doi:10.1016/j.actbio.2017.05.013 · Cited by 190

Exosomes serve as novel modes of tick-borne flavivirus transmission from arthropod to human cells and facilitates dissemination of viral RNA and proteins to the vertebrate neuronal cells

Zhou, W., Woodson, M., Neupane, B., Bai, F., Sherman, M. B., Choi, K. H., Neelakanta, G., & Sultana, H. (2018) · PLoS Pathogens · doi:10.1371/journal.ppat.1006764 · Cited by 185

Exosomes as natural nanocarrier-based drug delivery system: recent insights and future perspectives

Sen, S., Xavier, J., Kumar, N., Ahmad, M. Z., & Ranjan, O. P. (2023) · 3 Biotech · doi:10.1007/s13205-023-03521-2 · Cited by 195

Exosomes participate in the alteration of muscle homeostasis during lipid-induced insulin resistance in mice

Aswad, H., Forterre, A., Wiklander, O. P. B., Vial, G., Danty-Berger, E., Jalabert, A., Lamazière, A., Meugnier, E., Pesenti, S., Ott, C., et al. (2014) · Diabetologia · doi:10.1007/s00125-014-3337-2 · Cited by 185

IFNγ-stimulated dendritic cell exosomes as a potential therapeutic for remyelination

Pusic, A. D., Pusic, K. M., Clayton, B. L. L., & Kraig, R. P. (2013) · Journal of Neuroimmunology · doi:10.1016/j.jneuroim.2013.10.014 · Cited by 185

Exosomal transfer of miR-30a between cardiomyocytes regulates autophagy after hypoxia

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