Cited by 180Fibromyalgia and Chronic Fatigue Syndrome ResearchMusculoskeletal pain and rehabilitationMedical Practices and Rehabilitation

Multidisciplinary rehabilitation for fibromyalgia and musculoskeletal pain in working age adults

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Karjalainen, Kaija A, Malmivaara, Antti, van Tulder, Maurits W, Roine, Risto, Jauhiainen, Merja, Hurri, Heikki, Koes, Bart W·1999·Cochrane Database of Systematic Reviews

Abstract

BACKGROUND: Non-malignant musculoskeletal pain is an increasing problem in western countries. Fibromyalgia syndrome is an increasing recognised chronic musculoskeletal disorder. OBJECTIVES: The objective of this systematic review was to determine the effectiveness of multidisciplinary rehabilitation for fibromyalgia and widespread musculoskeletal pain among working age adults. SEARCH STRATEGY: An electronic search was conducted and included Medline from 1966, PsycLIT from 1967 and EMBASE from 1980 to April 1998. The Cochrane Musculoskeletal Group Trials Register was searched as well as, the Cochrane Controlled Trials Register (CCTR). The references of identified articles and reviews were checked, studies published in the Finnish medical database Medic from 1978 to 1998 screened and the Science Citation Index searched. Content experts were also contacted for additional or unpublished studies. SELECTION CRITERIA: From all references found in our original search, we selected all randomized controlled trials (RCTs) and clinical controlled trials (CCTs). Trials had to assess the effectiveness of multidisciplinary rehabilitation for patients suffering from fibromyalgia and widespread musculoskeletal pain among working age adults. The rehabilitation program was required to be multidisciplinary; that is, it had to consist of a physician's consultation, plus a psychological, social or vocational intervention, or a combination of both. DATA COLLECTION AND ANALYSIS: Four reviewers independently selected the RCTs and CCTs that met the specified inclusion criteria. Two experts in the field of rehabilitation evaluated the relevance and applicability of the findings of the selected studies to actual clinical use. Two other reviewers extracted the data and assessed the main results and the methodological quality of the studies using standardized forms. Finally, a qualitative analysis was performed to evaluate the level of scientific evidence for the effectiveness of multidisciplinary rehabilitation. MAIN RESULTS: After screening 1808 abstracts, and the references of 65 reviews, we found only seven relevant studies (1050 patients) that met our inclusion criteria. None of these were considered, methodologically, a high quality randomized controlled trial. Four of the included RCTs on fibromyalgia were graded low quality and suggest no quantifiable benefits. The three included RCTs on widespread musculoskeletal pain showed that based on limited evidence, overall, no evidence of efficacy was observed. However, behavioral treatment and stress management appear to be important components. Education combined with physical training showed some positive effects in long term follow up. REVIEWER'S CONCLUSIONS: We conclude that there appears to be little scientific evidence for the effectiveness of multidisciplinary rehabilitation for these musculoskeletal disorders. However, multidisciplinary rehabilitation is a commonly used intervention for chronic musculoskeletal disorders, which cause much personal suffering and substantial economic loss to the society. There is a need for high quality trials in this field.

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  1. Mulrow CD, Oxman AD (eds). Cochrane Collaboration Handbook (updated 1 March 1997). In: The Cochrane Library (database on disk and CDROM). The Cochrane Collaboration. Oxford: Update Software; 1996‐Updated quarterly. [Google Scholar]

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Authors
Karjalainen, K. A., Malmivaara, A., van Tulder, M. W., Roine, R., Jauhiainen, M., Hurri, H., & Koes, B. W.
Affiliations
  • Finnish Institute of Occupational Health (FI)
  • Finnish Office for Health Care Technology Assessment; Occupational Medicine; Lintulahdenkuja 4 Helsinki Finland FIN-00530
  • Faculty of Earth & Life Sciences, VU University; Department of Health Economics & Health Technology Assessment, Institute of Health Sciences; De Boelelaan 1081, room U443 Amsterdam Netherlands 1081 HV
  • Helsinki University Hospital (FI)
  • Tekonivelsairaala Orton (FI)
  • Erasmus MC (NL)
Venue
Cochrane Database of Systematic Reviews
Publisher
Wiley
Published
1999-07-26
Volume
2010
Issue
1
Pages
CD001984-CD001984
ISSN
  • 1361-6137 (ISSN-L)
  • 1465-1858
OpenAlex
W2123364617
Cited by
180
References
28
Citations by year
2025: 5 · 2023: 2 · 2022: 8 · 2021: 2 · 2020: 4 · 2019: 5 · 2018: 1 · 2017: 5 · 2016: 8 · 2015: 6 · 2014: 7 · 2013: 7 · 2012: 11
FWCI
0.33
Type
journal article
Language
en
Open access
Locations
  • Cochrane Database of Systematic Reviews (publishedVersion)
  • PubMed Central (publishedVersion)
  • PubMed (publishedVersion)
  • EUR Research Repository (Erasmus University Rotterdam) (submittedVersion)
  • VU Research Portal (submittedVersion)
  • Data Archiving and Networked Services (DANS) (submittedVersion)
Topics
  • Health Sciences › Medicine › Psychiatry and Mental health › Fibromyalgia and Chronic Fatigue Syndrome Research
  • Health Sciences › Medicine › Pharmacology › Musculoskeletal pain and rehabilitation
  • Health Sciences › Health Professions › Physical Therapy, Sports Therapy and Rehabilitation › Medical Practices and Rehabilitation
Keywords
fibromyalgia, chronic widespread pain, multidisciplinary rehabilitation, working-age adults, treatment effectiveness, behavior therapy, stress management, patient education, exercise training, psychological intervention, vocational interventions, chronic pain, methodological quality of trials, long-term outcomes, rehabilitation funding
MeSH terms
Adult, Chronic Disease, Fibromyalgia, Humans, Musculoskeletal Diseases, Pain, Pain Management

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