A Bioresorbable Dynamic Pressure Sensor for Cardiovascular Postoperative Care
Abstract
Bioresorbable electronics that can be absorbed and become part of the organism after their service life are a new trend to avoid secondary invasive surgery. However, the material limitation is a significant challenge. There are fewer biodegradable materials with pressure‐sensitive properties. Here, a pressure sensor based on the triboelectric effect between bioabsorbable materials is reported. This effect is available in almost all materials. The bioresorbable triboelectric sensor (BTS) can directly convert ambient pressure changes into electrical signals. This device successfully identifies abnormal vascular occlusion events in large animals (dogs). The service life of the BTS reaches 5 days with a high service efficiency (5.95%). The BTS offers excellent sensitivity (11 mV mmHg−1), linearity (R2 = 0.993), and good durability (450 000 cycles). The antibacterial bioresorbable materials (poly(lactic acid)–(chitosan 4%)) for the BTS can achieve 99% sterilization. Triboelectric devices are expected to be applied in postoperative care as bioresorbable electronics.
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Normal functions of the heart and blood vessels, recovery progress of injured tissue, and abnormality of central nervous signal require devices to be implanted inside the body for long-term status monitoring.
“For example, the normal functions of the heart and blood vessels (Ouyang et al. 2021), the recovery progress of the injured tissue (Zhang et al. 2021), and the abnormality of the central nervous signal (Shin et al. 2021), etc., all of which require devices to be implanted inside the body for a long-term status monitoring (Jiang et al. 2020).”
From Artificial intelligence enhanced sensors - enabling technologies to next-generation healthcare and biomedical platform (2023) · cites this paper as Ouyang et al. 2021
BTS has the potential to improve patient outcomes by providing accurate and continuous pressure monitoring without the risks associated with permanent implants.
“BTS has the potential to improve patient outcomes by providing accurate and continuous pressure monitoring without the risks associated with permanent implants.”
From Artificial intelligence enhanced sensors - enabling technologies to next-generation healthcare and biomedical platform (2023) · cites this paper as Ouyang et al. 2021
BTS bioresorbable triboelectric sensor for cardiovascular postoperative care can monitor pressure changes in real-time.
“Based on the triboelectric effect, BTS was designed to be implanted in the body and was capable of monitoring pressure changes in realtime.”
From Artificial intelligence enhanced sensors - enabling technologies to next-generation healthcare and biomedical platform (2023) · cites this paper as Ouyang et al. 2021
Cites
Piezoelectric Nanogenerators Based on Zinc Oxide Nanowire Arrays
Wang, Z. L., & Song, J. (2006) · Science · doi:10.1126/science.1124005 · Cited by 7,922 · see citing works
Self-citationFlexible triboelectric generator
Fan, F.-R., Tian, Z.-Q., & Lin Wang, Z. (2012) · Nano Energy · doi:10.1016/j.nanoen.2012.01.004 · Cited by 6,705 · see citing works
The return of a forgotten polymer—Polycaprolactone in the 21st century
Woodruff, M. A., & Hutmacher, D. W. (2010) · Progress in Polymer Science · doi:10.1016/j.progpolymsci.2010.04.002 · Cited by 4,033 · see citing works
Quantifying the triboelectric series
Zou, H., Zhang, Y., Guo, L., Wang, P., He, X. C., Dai, G., Zheng, H., Chen, C.-Y., Wang, A. C., Xu, C., et al. (2019) · Nature Communications · doi:10.1038/s41467-019-09461-x · Cited by 1,939 · see citing works
Self-citationFlexible Nanogenerators for Energy Harvesting and Self‐Powered Electronics
Fan, F. R., Tang, W., & Wang, Z. L. (2016) · Advanced Materials · doi:10.1002/adma.201504299 · Cited by 1,916 · see citing works
Self-citationDissolvable films of silk fibroin for ultrathin conformal bio-integrated electronics
Kim, D.-H., Viventi, J., Amsden, J. J., Xiao, J., Vigeland, L., Kim, Y.-S., Blanco, J. A., Panilaitis, B., Frechette, E. S., Contreras, D., et al. (2010) · Nature Materials · doi:10.1038/nmat2745 · Cited by 1,721 · see citing works
“Green” electronics: biodegradable and biocompatible materials and devices for sustainable future
Irimia‐Vladu, M. (2013) · Chemical Society Reviews · doi:10.1039/c3cs60235d · Cited by 1,046 · see citing works
Bioresorbable silicon electronic sensors for the brain
Kang, S.-K., Murphy, R. K. J., Hwang, S.-W., Lee, S. M., Harburg, D. V., Krueger, N. A., Shin, J., Gamble, P., Cheng, H., Yu, S., et al. (2016) · Nature · doi:10.1038/nature16492 · Cited by 998 · see citing works
High-performance green flexible electronics based on biodegradable cellulose nanofibril paper
Jung, Y. H., Chang, T., Zhang, H., Yao, C. J., Zheng, Q., Yang, V. W., Mi, H., Kim, M., Cho, S. J., Park, D., et al. (2015) · Nature Communications · doi:10.1038/ncomms8170 · Cited by 891 · see citing works
Peng, X., Dong, K., Ye, C., Jiang, Y., Zhai, S., Cheng, R., Liu, D., Gao, X., Wang, J., & Wang, Z. L. (2020) · Science Advances · doi:10.1126/sciadv.aba9624 · Cited by 886 · see citing works
Self-citationPiezoelectric Biomaterials for Sensors and Actuators
Chorsi, M. T., Curry, E. J., Chorsi, H. T., Das, R., Baroody, J., Purohit, P. K., Ilieş, H., & Nguyen, T. D. (2018) · Advanced Materials · doi:10.1002/adma.201802084 · Cited by 879 · see citing works
Design of biodegradable, implantable devices towards clinical translation
Li, C., Guo, C., Fitzpatrick, V., Ibrahim, A. G. A., Zwierstra, M. J., Hanna, P. C., Lechtig, A., Nazarian, A., Lin, S. J., & Kaplan, D. L. (2019) · Nature Reviews Materials · doi:10.1038/s41578-019-0150-z · Cited by 819 · see citing works
Lin, S., Xu, L., Wang, A. C., & Wang, Z. L. (2020) · Nature Communications · doi:10.1038/s41467-019-14278-9 · Cited by 688 · see citing works
Self-citationBiodegradable triboelectric nanogenerator as a life-time designed implantable power source
Zheng, Q., Zou, Y., Zhang, Y., Liu, Z., Shi, B., Wang, X., Jin, Y., Ouyang, H., Li, Z., & Wang, Z. L. (2016) · Science Advances · doi:10.1126/sciadv.1501478 · Cited by 617 · see citing works
Self-citationLin, L., Xie, Y., Wang, S., Wu, W., Niu, S., Wen, X., & Wang, Z. L. (2013) · ACS Nano · doi:10.1021/nn4037514 · Cited by 606 · see citing works
Self-citationIn Vivo Powering of Pacemaker by Breathing‐Driven Implanted Triboelectric Nanogenerator
Zheng, Q., Shi, B., Fan, F., Wang, X., Yan, L., Yuan, W., Wang, S., Liu, H., Li, Z., & Wang, Z. L. (2014) · Advanced Materials · doi:10.1002/adma.201402064 · Cited by 603 · see citing works
Self-citationSilk Fibroin for Flexible Electronic Devices
Zhu, B., Wang, H., Leow, W. R., Cai, Y., Loh, X. J., Han, M., & Chen, X. (2015) · Advanced Materials · doi:10.1002/adma.201504276 · Cited by 597 · see citing works
Tissue–electronics interfaces: from implantable devices to engineered tissues
Feiner, R., & Dvir, T. (2017) · Nature Reviews Materials · doi:10.1038/natrevmats.2017.76 · Cited by 595 · see citing works
Novel Citric Acid‐Based Biodegradable Elastomers for Tissue Engineering
Yang, J. Y., Webb, A. R., & Ameer, G. A. (2004) · Advanced Materials · doi:10.1002/adma.200306264 · Cited by 591 · see citing works
Hong, Y. J., Jeong, H., Cho, K. W., Lu, N., & Kim, D. (2019) · Advanced Functional Materials · doi:10.1002/adfm.201808247 · Cited by 559 · see citing works
Quantifying and understanding the triboelectric series of inorganic non-metallic materials
Zou, H., Guo, L., Xue, H., Zhang, Y., Shen, X., Liu, X., Wang, P., He, X. C., Dai, G., Jiang, P., et al. (2020) · Nature Communications · doi:10.1038/s41467-020-15926-1 · Cited by 549 · see citing works
Self-citationResilient yet entirely degradable gelatin-based biogels for soft robots and electronics
Baumgartner, M., Hartmann, F., Drack, M., Preninger, D., Wirthl, D., Gerstmayr, R., Lehner, L. E., Mao, G., Pruckner, R., Demchyshyn, S., et al. (2020) · Nature Materials · doi:10.1038/s41563-020-0699-3 · Cited by 536 · see citing works
Self‐Powered Pulse Sensor for Antidiastole of Cardiovascular Disease
Ouyang, H., Tian, J., Sun, G., Zou, Y., Liu, Z., Li, H., Zhao, L., Shi, B., Fan, Y., Fan, Y., et al. (2017) · Advanced Materials · doi:10.1002/adma.201703456 · Cited by 468 · see citing works
Self-citationMuscle‐Driven In Vivo Nanogenerator
Li, Z., Zhu, G., Yang, R., Wang, A. C., & Wang, Z. L. (2010) · Advanced Materials · doi:10.1002/adma.200904355 · Cited by 441 · see citing works
Self-citationBiodegradable Piezoelectric Force Sensor
Curry, E. J., Ke, K., Chorsi, M. T., Wrobel, K. S., Miller, A. N., Patel, A., Kim, I.-S., Feng, J., Yue, L., Wu, Q., et al. (2018) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1710874115 · Cited by 434 · see citing works
Biodegradable Materials and Green Processing for Green Electronics
Li, W., Liu, Q., Zhang, Y., Li, C., He, Z., Choy, W. C. H., Low, P. J., Sonar, P. M., & Kyaw, A. K. K. (2020) · Advanced Materials · doi:10.1002/adma.202001591 · Cited by 396 · see citing works
Self-powered cardiovascular electronic devices and systems
Zheng, Q., Tang, Q., Wang, Z. L., & Li, Z. (2021) · Nature Reviews Cardiology · doi:10.1038/s41569-020-0426-4 · Cited by 348 · see citing works
Self-citationBiodegradable nanofiber-based piezoelectric transducer
Curry, E. J., Le, T. T., Das, R., Ke, K., Santorella, E. M., Paul, D., Chorsi, M. T., Tran, K. T. M., Baroody, J., Borges, E. R., et al. (2019) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1910343117 · Cited by 297 · see citing works
Wang, R., Gao, S., Yang, Z., et al. (2018) · Advanced Materials · doi:10.1002/adma.201706267 · Cited by 292 · see citing works
Silk Nanofiber‐Networked Bio‐Triboelectric Generator: Silk Bio‐TEG
Kim, H., Kim, J., Jun, K., et al. (2016) · Advanced Energy Materials · doi:10.1002/aenm.201502329 · Cited by 288 · see citing works
Pumping up the charge density of a triboelectric nanogenerator by charge-shuttling
Wang, H., Xu, L., Bai, Y., & Wang, Z. L. (2020) · Nature Communications · doi:10.1038/s41467-020-17891-1 · Cited by 247 · see citing works
Self-citationWearable and Implantable Electronics: Moving toward Precision Therapy
Song, Y., Min, J., & Gao, W. F. (2019) · ACS Nano · doi:10.1021/acsnano.9b08323 · Cited by 232 · see citing works
Advanced Materials and Systems for Biodegradable, Transient Electronics
Han, W. B., Lee, J. H., Shin, J., & Hwang, S. (2020) · Advanced Materials · doi:10.1002/adma.202002211 · Cited by 225 · see citing works
Liu, Z., Zhao, Z., Zeng, X., Fu, X., & Hu, Y. (2019) · Nano Energy · doi:10.1016/j.nanoen.2019.02.057 · Cited by 224 · see citing works
Self-citationA Fully Biodegradable Battery for Self‐Powered Transient Implants
Huang, X., Wang, D., Yuan, Z., Xie, W., Wu, Y., Li, R., Zhao, Y., Luo, D., Cen, L., Chen, B., et al. (2018) · Small · doi:10.1002/smll.201800994 · Cited by 200 · see citing works
25th Anniversary Article: Materials for High‐Performance Biodegradable Semiconductor Devices
Hwang, S., Park, G., Cheng, H., Song, J., Kang, S., Yin, L., Kim, J., Omenetto, F. G., Huang, Y. Y., Lee, K., et al. (2014) · Advanced Materials · doi:10.1002/adma.201304821 · Cited by 191 · see citing works
Triboelectric nanogenerator based on degradable materials
Chao, S., Ouyang, H., Jiang, D., Fan, Y., & Li, Z. (2020) · EcoMat · doi:10.1002/eom2.12072 · Cited by 188 · see citing works
Self-citationOptimization principles and the figure of merit for triboelectric generators
Peng, J., Kang, S. D., & Snyder, G. J. (2017) · Science Advances · doi:10.1126/sciadv.aap8576 · Cited by 186 · see citing works
Materials chemistry in flexible electronics
Chen, X., Rogers, J. A., Lacour, S. P., et al. (2019) · Chemical Society Reviews · doi:10.1039/c9cs90019e · Cited by 174 · see citing works
Fully Bioabsorbable Capacitor as an Energy Storage Unit for Implantable Medical Electronics
Li, H., Zhao, C., Wang, X., Meng, J., Zou, Y., Noreen, S., Zhao, L., Liu, Z., Ouyang, H., Tan, P., et al. (2019) · Advanced Science · doi:10.1002/advs.201801625 · Cited by 157 · see citing works
Self-citationTsang, M., Armutlulu, A., Martinez, A. W., Allen, S. A. B., & Allen, M. G. (2015) · Microsystems & Nanoengineering · doi:10.1038/micronano.2015.24 · Cited by 119 · see citing works
Injectable Biomedical Devices for Sensing and Stimulating Internal Body Organs
Jung, Y. H., Kim, J. U., Lee, J. S., Shin, J. H., Jung, W., Ok, J., & Kim, T. (2020) · Advanced Materials · doi:10.1002/adma.201907478 · Cited by 88 · see citing works
Jeong, C. G., & Hollister, S. J. (2010) · Journal of Biomedical Materials Research Part B Applied Biomaterials · doi:10.1002/jbm.b.31568 · Cited by 80 · see citing works
Romero, A. D. C. B., da Silva, C. E., & de Aguiar, P. H. P. (2011) · Surgical Neurology International · doi:10.4103/2152-7806.82373 · Cited by 11 · see citing works
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Wang, C., He, T., Zhou, H., Zhang, Z., & Lee, C. (2023) · Bioelectronic Medicine · doi:10.1186/s42234-023-00118-1 · Cited by 295 · see citing works
- Authors
- Ouyang, H., Li, Z., Gu, M., Hu, Y., Xu, L., Jiang, D., Cheng, S., Zou, Y., Deng, Y., Shi, B., Hua, W., Fan, Y., Li, Z., & Wang, Z.
- Affiliations
- Chinese Academy of Sciences (CN)
- Beijing Institute of Technology (CN)
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- Beihang University (CN)
- CAS Center for Excellence in Nanoscience Beijing Key Laboratory of Micro‐Nano Energy and Sensor Beijing Institute of Nanoenergy and Nanosystems Chinese Academy of Sciences Beijing 100083 China
- Corresponding author
- Hua, Wei
- Fan, Yubo
- Li, Zhou
- ORCID
- Venue
- Advanced Materials
- Publisher
- Wiley
- Published
- 2021-08-08
- Volume
- 33
- Issue
- 39
- Pages
- e2102302-e2102302
- ISSN
- 0935-9648 (ISSN-L)
- 1521-4095
- OpenAlex
- W3192693634
- Cited by
- 160
- References
- 44
- Citations by year
- 2026: 15 · 2025: 31 · 2024: 36 · 2023: 43 · 2022: 31 · 2021: 4
- FWCI
- 8.66
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Advanced Materials (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Natural Science Foundation of China (61875015, 62004010, U20A20390, 11827803)
- China Postdoctoral Science Foundation (2019M660410)
- Natural Science Foundation of Beijing Municipality (JQ20038)
- Topics
- Physical Sciences › Engineering › Biomedical Engineering › Advanced Sensor and Energy Harvesting Materials
- Physical Sciences › Engineering › Biomedical Engineering › Non-Invasive Vital Sign Monitoring
- Physical Sciences › Materials Science › Biomaterials › biodegradable polymer synthesis and properties
- Keywords
- bioresorbable electronics, bioresorbable materials, postoperative care, polylactic acid, chitosan, antibacterial materials, sterilization, biodegradable sensors
- MeSH terms
- Animals, Biocompatible Materials, Cardiovascular Diseases, Dogs, Dyspnea, Electronics, Monitoring, Physiologic, Polyesters, Postoperative Care, Absorbable Implants, Mice
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