Cited by 559Advanced Sensor and Energy Harvesting MaterialsNon-Invasive Vital Sign MonitoringNeuroscience and Neural Engineering

Wearable and Implantable Devices for Cardiovascular Healthcare: from Monitoring to Therapy Based on Flexible and Stretchable Electronics

Hong, Yongseok Joseph, Jeong, Hyoyoung, Cho, Kyoung Won, Lu, Nanshu, Kim, Dae‐Hyeong·2019·Advanced Functional Materials

Abstract

Cardiovascular disease is the leading cause of death and has dramatically increased in recent years. Continuous cardiac monitoring is particularly important for early diagnosis and prevention, and flexible and stretchable electronic devices have emerged as effective tools for this purpose. Their thin, soft, and deformable features allow intimate and long‐term integration with biotissues, which enables continuous, high‐fidelity, and sometimes large‐area cardiac monitoring on the skin and/or heart surface. In addition to monitoring, intimate contact is also crucial for high‐precision therapies. Combined with tissue engineering, soft bioelectronics have also demonstrated the capability to repair damaged cardiac tissues. This review highlights the recent advances in wearable and implantable devices based on flexible and stretchable electronics for cardiovascular monitoring and therapy. First, wearable/implantable soft bioelectronics for cardiovascular monitoring (e.g., the electrocardiogram, blood pressure, and oxygen saturation level) are reviewed. Then, advances in cardiovascular therapy based on soft bioelectronics (e.g., mesh pacing, ablation, robotic sleeves, and electronic stents) are discussed. Finally, device‐assisted tissue engineering therapy (e.g., functional electronic scaffolds and in vitro cardiac platforms) is discussed.

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Crossref · 10.1002/adfm.201808247

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Authors
Hong, Y. J., Jeong, H., Cho, K. W., Lu, N., & Kim, D.
Affiliations
  • Seoul National University (KR)
  • The University of Texas at Austin (US)
Corresponding author
  • Lu, Nanshu
  • Kim, Dae‐Hyeong
Venue
Advanced Functional Materials
Publisher
Wiley
Published
2019-02-27
Volume
29
Issue
19
ISSN
  • 1616-301X (ISSN-L)
  • 1616-3028
OpenAlex
W2918664767
Cited by
559
References
298
Citations by year
2026: 35 · 2025: 89 · 2024: 91 · 2023: 95 · 2022: 73 · 2021: 88 · 2020: 66 · 2019: 22
FWCI
21.92
Type
journal article
Language
en
Open access
closed
Locations
  • Advanced Functional Materials (publishedVersion)
  • Seoul National University Open Repository (Seoul National University) (submittedVersion)
Funders
  • Office of Naval Research (N00014‐16‐1‐2044)
  • National Research Foundation of Korea
Topics
  • Physical Sciences › Engineering › Biomedical Engineering › Advanced Sensor and Energy Harvesting Materials
  • Physical Sciences › Engineering › Biomedical Engineering › Non-Invasive Vital Sign Monitoring
  • Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neuroscience and Neural Engineering
Keywords
wearable devices, biomedical implants, flexible electronics, stretchable electronics, soft bioelectronics, cardiovascular monitoring, cardiac pacing, cardiac ablation, tissue engineering, in vitro cardiac models, electrocardiogram, blood pressure monitoring, oxygen saturation monitoring, cardiac repair

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