Muscle‐Driven In Vivo Nanogenerator
Abstract
A nanogenerator based on a single piezoelectric fine wire producing an alternating current (AC) is successfully used for the harvesting of biomechanical energy under in vivo conditions. We demonstrate the implanting and working of such a nanogenerator in a live rat where it harvests energy generated by its breathing or heart beating. This study shows the potential of applying these nanogenerators for driving in vivo nanodevices.
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Triggered by the heartbeat motions of a live rat, the ZnO SWG generates an average voltage and current of 3 mV and 30 pA, respectively.
“Triggered by the heartbeat motions of a live rat, the SWG can generate an average voltage and current of 3 mV and 30 pA, respectively.”
From From flexible electronics technology in the era of IoT and artificial intelligence toward future implanted body sensor networks (2019) · cites this paper as [69]
This research opens up the possibility to harvest biomechanical energy from the in vivo environment, e.g., heartbeat, muscle stretching, blood pressure, breath, and other vibrations.
“This research opens up the possibility to harvest the biomechanical energy from the in vivo environment, e.g., heartbeat, muscle stretching, blood pressure, breath, and other vibrations.”
From From flexible electronics technology in the era of IoT and artificial intelligence toward future implanted body sensor networks (2019) · cites this paper as [69]
An implantable ZnO single-wire generator is demonstrated to harvest biomechanical energy inside a rat.
“To harvest the biomechanical energy inside a rat, an implantable ZnO single-wire generator (SWG) is demonstrated [Fig.2(h)].69”
From From flexible electronics technology in the era of IoT and artificial intelligence toward future implanted body sensor networks (2019) · cites this paper as [69]
Cites
Direct-Current Nanogenerator Driven by Ultrasonic Waves
Wang, X., Song, J., Jin, L., & Wang, Z. L. (2007) · Science · doi:10.1126/science.1139366 · Cited by 2,258 · see citing works
Self-citationPower generation with laterally packaged piezoelectric fine wires
Yang, R., Qin, Y., Dai, L., & Wang, Z. L. (2008) · Nature Nanotechnology · doi:10.1038/nnano.2008.314 · Cited by 931 · see citing works
Self-citationConverting Biomechanical Energy into Electricity by a Muscle-Movement-Driven Nanogenerator
Yang, R., Qin, Y., Cheng, L., Zhu, G., & Wang, Z. L. (2009) · Nano Letters · doi:10.1021/nl803904b · Cited by 492 · see citing works
Self-citationCellular Level Biocompatibility and Biosafety of ZnO Nanowires
Li, Z., Yang, R., Yu, M., Bai, F., Li, C., & Wang, Z. L. (2008) · The Journal of Physical Chemistry C · doi:10.1021/jp808878p · Cited by 329 · see citing works
Self-citationThe Use of Piezoelectric Ceramics for Electric Power Generation Within Orthopedic Implants
Platt, S. R., Farritor, S. M., Garvin, K. L., & Haider, H. (2005) · IEEE/ASME Transactions on Mechatronics · doi:10.1109/tmech.2005.852482 · Cited by 233 · see citing works
Integrated Multilayer Nanogenerator Fabricated Using Paired Nanotip-to-Nanowire Brushes
Xu, S., Wei, Y., Liu, J., Yang, R., & Wang, Z. L. (2008) · Nano Letters · doi:10.1021/nl8027813 · Cited by 161 · see citing works
Self-citationCharacteristics of output voltage and current of integrated nanogenerators
Yang, R., Qin, Y., Li, C., Dai, L., & Wang, Z. L. (2009) · Applied Physics Letters · doi:10.1063/1.3072362 · Cited by 146 · see citing works
Self-citationImplantable physiological power supply with PVDF film
Häsler, E., Stein, L., & Harbauer, G. (1984) · Ferroelectrics · doi:10.1080/00150198408017528 · Cited by 144 · see citing works
Reformation of Organized Connections in the Auditory System After Generation of the Eighth Nerve
Zakon, H. H., & Capranica, R. R. (1981) · Science · doi:10.1126/science.6972599 · Cited by 23 · see citing works
Microstructure and piezoelectric properties of PVDF films
Häusler, E., Kaufmann, W., Petermann, J., et al. (1984) · Ferroelectrics · doi:10.1080/00150198408017508 · Cited by 11 · see citing works
Flagged first, then by citations
Cited by
Sorted by citations
Self-powered ultra-flexible electronics via nano-grating-patterned organic photovoltaics
Park, S., Heo, S. W., Lee, W., Inoue, D., Jiang, Z., Yu, K., Jinno, H., Hashizume, D., Sekino, M., Yokota, T., et al. (2018) · Nature · doi:10.1038/s41586-018-0536-x · Cited by 1,068 · see citing works
Nanotechnology‐Enabled Energy Harvesting for Self‐Powered Micro‐/Nanosystems
Wang, Z. L., & Wu, W. (2012) · Angewandte Chemie International Edition · doi:10.1002/anie.201201656 · Cited by 1,063 · see citing works
Self-citationTranscutaneous ultrasound energy harvesting using capacitive triboelectric technology
Hinchet, R., Yoon, H.-J., Ryu, H., Kim, M.-K., Choi, E.-K., Kim, D.-S., & Kim, S.-W. (2019) · Science · doi:10.1126/science.aan3997 · Cited by 854 · see citing works
Biodegradable triboelectric nanogenerator as a life-time designed implantable power source
Zheng, Q., Zou, Y., Zhang, Y., Liu, Z., Shi, B., Wang, X., Jin, Y., Ouyang, H., Li, Z., & Wang, Z. L. (2016) · Science Advances · doi:10.1126/sciadv.1501478 · Cited by 617 · see citing works
Self-citationIn Vivo Powering of Pacemaker by Breathing‐Driven Implanted Triboelectric Nanogenerator
Zheng, Q., Shi, B., Fan, F., Wang, X., Yan, L., Yuan, W., Wang, S., Liu, H., Li, Z., & Wang, Z. L. (2014) · Advanced Materials · doi:10.1002/adma.201402064 · Cited by 603 · see citing works
Self-citationHighly Stretchable Piezoelectric‐Pyroelectric Hybrid Nanogenerator
Lee, J., Lee, K. Y., Gupta, M. K., Kim, T. Y., Lee, D., Oh, J., Ryu, C., Yoo, W. J., Kang, C., Yoon, S., et al. (2014) · Advanced Materials · doi:10.1002/adma.201303570 · Cited by 550 · see citing works
Zheng, Q., Zhang, H., Shi, B., Xue, X., Liu, Z., Jin, Y., Ma, Y., Zou, Y., Wang, X., An, Z., et al. (2016) · ACS Nano · doi:10.1021/acsnano.6b02693 · Cited by 449 · see citing works
Self-citationFully Bioabsorbable Natural‐Materials‐Based Triboelectric Nanogenerators
Jiang, W., Li, H., Liu, Z., Li, Z., Tian, J., Shi, B., Zou, Y., Ouyang, H., Zhao, C., Zhao, L., et al. (2018) · Advanced Materials · doi:10.1002/adma.201801895 · Cited by 449 · see citing works
Self-citationSelf-powered cardiovascular electronic devices and systems
Zheng, Q., Tang, Q., Wang, Z. L., & Li, Z. (2021) · Nature Reviews Cardiology · doi:10.1038/s41569-020-0426-4 · Cited by 348 · see citing works
Self-citationEnergy autonomous electronic skin
García Núñez, C., Manjakkal, L., & Dahiya, R. (2019) · npj Flexible Electronics · doi:10.1038/s41528-018-0045-x · Cited by 332 · see citing works
“3f).(55,118) In this scenario, the mechanical energy produced by a NW-based nanogenerator attached to either the body of a rat (Fig.”
BackgroundTranscatheter Self‐Powered Ultrasensitive Endocardial Pressure Sensor
Liu, Z., Ma, Y., Ouyang, H., Shi, B., Li, N., Jiang, D., Xie, F., Qu, D., Zou, Y., Huang, Y., et al. (2019) · Advanced Functional Materials · doi:10.1002/adfm.201807560 · Cited by 308 · see citing works
Self-citationProgress of flexible strain sensors for physiological signal monitoring
Shen, Z., Liu, F., Huang, S., Wang, H., Yang, C., Hang, T., Tao, J., Xia, W., & Xie, X. (2022) · Biosensors and Bioelectronics · doi:10.1016/j.bios.2022.114298 · Cited by 250 · see citing works
In Vivo Self‐Powered Wireless Transmission Using Biocompatible Flexible Energy Harvesters
Kim, D. H., Shin, H. J., Lee, H., Jeong, C. K., Park, H., Hwang, G., Lee, H., Joe, D. J., Han, J. H., Lee, S. H., et al. (2017) · Advanced Functional Materials · doi:10.1002/adfm.201700341 · Cited by 245 · see citing works
Lee, S., Shi, Q., & Lee, C. (2019) · APL Materials · doi:10.1063/1.5063498 · Cited by 164 · see citing works
A Bioresorbable Dynamic Pressure Sensor for Cardiovascular Postoperative Care
Ouyang, H., Li, Z., Gu, M., Hu, Y., Xu, L., Jiang, D., Cheng, S., Zou, Y., Deng, Y., Shi, B., et al. (2021) · Advanced Materials · doi:10.1002/adma.202102302 · Cited by 160 · see citing works
Self-citationSurvey of energy scavenging for wearable and implantable devices
Ghomian, T., & Mehraeen, S. (2019) · Energy · doi:10.1016/j.energy.2019.04.088 · Cited by 126 · see citing works
Wireless technologies for implantable devices
Nelson, B. D., Karipott, S. S., Wang, Y., & Ong, K. G. (2020) · Sensors · doi:10.3390/s20164604 · Cited by 125 · see citing works
Kim, K. N., Chun, J., Chae, S. A., Ahn, C. W., Kim, I. W., Kim, S.-W., Wang, Z. L., & Baik, J. M. (2015) · Nano Energy · doi:10.1016/j.nanoen.2015.01.004 · Cited by 116 · see citing works
Self-citationSelf-powered pulsed direct current stimulation system for enhancing osteogenesis in MC3T3-E1
Zhang, Y., Xu, L., Liu, Z., Cui, X., Xiang, Z., Bai, J., Jiang, D., Xue, J., Wang, C., Lin, Y., et al. (2021) · Nano Energy · doi:10.1016/j.nanoen.2021.106009 · Cited by 88 · see citing works
Self-citationActive photonic wireless power transfer into live tissues
Kim, J., Seo, J., Jung, D., Lee, T., Ju, H., Han, J., Kim, N., Jeong, J., Cho, S., Seol, J. H., et al. (2020) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2002201117 · Cited by 75 · see citing works
Zhou, W., Rahman, M. S. U., Sun, C., Li, S., Zhang, N., Chen, H., Han, C. C., Xu, S., & Liu, Y. (2024) · Advanced Materials · doi:10.1002/adma.202307805 · Cited by 65 · see citing works
Wang, J., Thow, X. Y., Wang, H., Lee, S., Voges, K., Thakor, N. V., Yen, S., & Lee, C. (2018) · Advanced Healthcare Materials · doi:10.1002/adhm.201700987 · Cited by 43 · see citing works
- Authors
- Li, Z., Zhu, G., Yang, R., Wang, A. C., & Wang, Z. L.
- Affiliations
- Georgia Institute of Technology (US)
- Corresponding author
- Wang, Zhong Lin
- Venue
- Advanced Materials
- Publisher
- Wiley
- Published
- 2010-06-18
- Volume
- 22
- Issue
- 23
- Pages
- 2534-2537
- ISSN
- 0935-9648 (ISSN-L)
- 1521-4095
- OpenAlex
- W2107784331
- Cited by
- 441
- References
- 10
- Citations by year
- 2026: 8 · 2025: 23 · 2024: 29 · 2023: 43 · 2022: 39 · 2021: 44 · 2020: 42 · 2019: 42 · 2018: 31 · 2017: 28 · 2016: 26 · 2015: 31 · 2014: 20 · 2013: 10 · 2012: 12
- FWCI
- 6.43
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Advanced Materials (publishedVersion)
- PubMed (publishedVersion)
- King Abdullah University of Science and Technology Repository (King Abdullah University of Science and Technology) (submittedVersion)
- Topics
- Physical Sciences › Engineering › Biomedical Engineering › Advanced Sensor and Energy Harvesting Materials
- Physical Sciences › Engineering › Mechanical Engineering › Innovative Energy Harvesting Technologies
- Physical Sciences › Engineering › Biomedical Engineering › Nanowire Synthesis and Applications
- Keywords
- piezoelectric nanogenerators, fine wires, biomechanical energy harvesting, breathing, heartbeat, rat model
- MeSH terms
- Animals, Biomechanical Phenomena, Heart, Male, Muscles, Electric Power Supplies, Respiration, Rats, Sprague-Dawley, Nanotechnology, Rats
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