The DOI matches its Crossref record; 12 of the 13 references it cites were found in a registry or an index.
Association of chemosensory dysfunction and COVID‐19 in patients presenting with influenza‐like symptoms
Open accessAbstract
Background: Rapid spread of the severe acute respiratory syndrome‐coronavirus‐2 (SARS‐CoV‐2) and concern for viral transmission by ambulatory patients with minimal to no symptoms underline the importance of identifying early or subclinical symptoms of coronavirus disease 2019 (COVID‐19) infection. Two such candidate symptoms include anecdotally reported loss of smell and taste. Understanding the timing and association of smell/taste loss in COVID‐19 may help facilitate screening and early isolation of cases. Methods: A single‐institution, cross‐sectional study evaluating patient‐reported symptoms with a focus on smell and taste was conducted using an internet‐based platform on adult subjects who underwent testing for COVID‐19. Logistic regression was employed to identify symptoms associated with COVID‐19 positivity. Results: A total of 1480 patients with influenza‐like symptoms underwent COVID‐19 testing between March 3, 2020, and March 29, 2020. Our study captured 59 of 102 (58%) COVID‐19–positive patients and 203 of 1378 (15%) COVID‐19–negative patients. Smell and taste loss were reported in 68% (40/59) and 71% (42/59) of COVID‐19–positive subjects, respectively, compared to 16% (33/203) and 17% (35/203) of COVID‐19–negative patients ( p < 0.001). Smell and taste impairment were independently and strongly associated with COVID‐19 positivity (anosmia: adjusted odds ratio [aOR] 10.9; 95% CI, 5.08‐23.5; ageusia: aOR 10.2; 95% CI, 4.74‐22.1), whereas sore throat was associated with COVID‐19 negativity (aOR 0.23; 95% CI, 0.11‐0.50). Of patients who reported COVID‐19–associated loss of smell, 74% (28/38) reported resolution of anosmia with clinical resolution of illness. Conclusion: In ambulatory individuals with influenza‐like symptoms, chemosensory dysfunction was strongly associated with COVID‐19 infection and should be considered when screening symptoms. Most will recover chemosensory function within weeks, paralleling resolution of other disease‐related symptoms.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“a symptom more specific to COVID‐19 infection is loss of taste and smell, in which loss of taste, or dysgeusia, occurs in approximately 88.8% of cases.”
From The oral microbiome: Role of key organisms and complex networks in oral health and disease (2021) · cites this paper as [297]
In the citing paper
“recovery from COVID-related anosmia often occurs over weeks (11, 17, 18)”
From Non-neuronal expression of SARS-CoV-2 entry genes in the olfactory system suggests mechanisms underlying COVID-19-associated anosmia (2020) · cites this paper as [18]
In the citing paper
“Any reasonable pathophysiological mechanism for COVID-19-associated anosmia must account for the high penetrance of smell disorders relative to endemic viruses (12, 91, 92), the apparent suddenness of smell loss that can precede the development of other symptoms (11, 13), and the transient nature of dysfunction in many patients (11, 17, 18); definitive identification of the disease mechanisms”
From Non-neuronal expression of SARS-CoV-2 entry genes in the olfactory system suggests mechanisms underlying COVID-19-associated anosmia (2020) · cites this paper as [18]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Presumed Asymptomatic Carrier Transmission of COVID-19
Bai, Y., Yao, L., Wei, T., Tian, F., Jin, D., Chen, L., & Wang, M. (2020) · JAMA · doi:10.1001/jama.2020.2565 · Cited by 4,496
Baig, A. M., Khaleeq, A., Ali, U., & Syeda, H. (2020) · ACS Chemical Neuroscience · doi:10.1021/acschemneuro.0c00122 · Cited by 2,207 · cited 1×
“Early studies evaluating mechanisms of SARS-CoV2-mediated olfactory loss have suggested neurotrophic targeting of olfactory neurons versus infection of non-neural olfactory epithelial cells.(5,6) The short-lived Covid-19-related olfactory loss found in our study favors a model in which SARS-CoV2 targets the olfactory…”
ResultGiacomelli, A., Pezzati, L., Conti, F., Bernacchia, D., Siano, M., Oreni, L., Rusconi, S., Gervasoni, C., Ridolfo, A. L., Rizzardini, G., et al. (2020) · Clinical Infectious Diseases · doi:10.1093/cid/ciaa330 · Cited by 1,326 · cited 1×
“5); (3) statistically significant associations (p < 0.”
Identification of Viruses in Patients With Postviral Olfactory Dysfunction
Suzuki, M., Saito, K., Min, W., Vladau, C., Toida, K., Itoh, H., & Murakami, S. (2007) · The Laryngoscope · doi:10.1097/01.mlg.0000249922.37381.1e · Cited by 383 · cited 1×
“05); and (4) we prioritized “any symptoms” (eg, any symptoms reported during the entire disease period) over “presenting symptoms” (eg, initial symptoms of presentation) because we had no a priori hypothesis for the natural history of anosmia and thus believed that inputting “any symptoms” for our multivariate correla…”
BackgroundBoesveldt, S., Postma, E. M., Boak, D., Welge‐Lüessen, A., Schöpf, V., Mainland, J. D., Martens, J. R., Ngai, J., & Duffy, V. B. (2017) · Chemical Senses · doi:10.1093/chemse/bjx025 · Cited by 376
Brann, D. H., Tsukahara, T., Weinreb, C., Lipovsek, M., den Berge, K. V., Gong, B., Chance, R., Macaulay, I. C., Chou, H.-J., Fletcher, R., et al. (2020) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2020.03.25.009084 · Cited by 306
Coincidence of COVID-19 epidemic and olfactory dysfunction outbreak
Bagheri, S. H., Asghari, A., Farhadi, M., Shamshiri, A. R., Kabir, A., Kamrava, S. K., Jalessi, M., Mohebbi, A., Alizadeh, R., Honarmand, A. A., et al. (2020) · doi:10.1101/2020.03.23.20041889 · Cited by 179
Qiu, C., Cui, C., Hautefort, C., Haehner, A., Zhao, J. F., Yao, Q., Zeng, H., Nisenbaum, E. J., Liu, L., Zhao, Y., et al. (2020) · Otolaryngology · doi:10.1177/0194599820934376 · Cited by 171
Proinflammatory Cytokines in the Olfactory Mucosa Result in COVID-19 Induced Anosmia
Torabi, A., Mohammadbagheri, E., Dilmaghani, N. A., Bayat, A., Fathi, M., Vakili, K. G., Alizadeh, R., Rezaeimirghaed, O., Hajiesmaeili, M., Ramezani, M., et al. (2020) · ACS Chemical Neuroscience · doi:10.1021/acschemneuro.0c00249 · Cited by 168
Chung, T. W., Sridhar, S., Zhang, J., Chan, K., Li, H., Wong, F. K.-C., Ng, M., Tsang, R. K., Lee, A. C.-Y., Fan, Z., et al. (2020) · Open Forum Infectious Diseases · doi:10.1093/ofid/ofaa199 · Cited by 106
Flagged first, then by citations
1 of the 13 references couldn’t be matched to a known paper.
Research works printed but not linked: 1
- Giacomelli A, Self‐reported olfactory and taste disorders in SARS‐CoV‐2 patients: a cross‐sectional study, Clin Infect Dis
Cited by
Sorted by citations
Items 501–600 of 752
Sebo, P., Maisonneuve, H., Lourdaux, J., Cuzin, C., Floquet, M., Tudrej, B. V., & Haller, D. M. (2021) · Family Practice · doi:10.1093/fampra/cmab009 · Cited by 5
Smell and taste disorders: warning signs for SARS-CoV-2 infection
da Costa, K. V. T., & Carnaúba, A. T. L. (2020) · Brazilian Journal of Otorhinolaryngology · doi:10.1016/j.bjorl.2020.05.003 · Cited by 5
Rahman, M. M., Bhattacharjee, B., Farhana, Z., Hamiduzzaman, M., Chowdhury, M. A. B., Hossain, M. S., Siddiqee, M. H., Islam, M. Z., Raheem, E., & Uddin, M. J. (2020) · medRxiv · doi:10.1101/2020.08.19.20177980 · Cited by 5
An Overview of COVID-19 Testing and Implications for OtolaryngologistsPreprint
Zhao, X. H. (2020) · doi:10.22541/au.158888305.59818836 · Cited by 5
ENT Manifestations in COVID-19 Positive PatientsPreprint
Kuchhal, V., Ahmad, S., Chaurasia, P., & Rawat, P. S. (2020) · doi:10.21203/rs.3.rs-90203/v1 · Cited by 5
Hasan, M. M., Tamanna, N. A., Jamal, M. N., & Uddin, M. J. (2021) · medRxiv · doi:10.1101/2021.01.27.21250153 · Cited by 5
Dear Watch, Should I get a COVID Test? Designing deployable machine learning for wearablesPreprint
Goldenberg, A., Nestor, B., Hunter, J., Kainkaryam, R., Drysdale, E., Inglis, J. B., Shapiro, A. D., Nagaraj, S., Ghassemi, M., & Foschini, L. (2021) · Research Square · doi:10.21203/rs.3.rs-505984/v1 · Cited by 5
“The symptoms which are more prevalent in COVID-19 negative ILI patients are cough and sore throat, though only sore-throat is statistically more likely to be associated with influenza [63].”
BackgroundTurabián, J. L. (2020) · Epidemiology International Journal · doi:10.23880/eij-16000s1-005 · Cited by 5
Priori, A., Bai, F., Rovito, R., Marchetti, G. C., Monforte, A. D., Papa, G. F. S., Pellegrino, G. M., Centanni, S., Chiumello, D., Bonifazi, M., et al. (2021) · doi:10.54103/milanoup.57 · Cited by 5
Chao, Y., Zhang, L., Chen, Q., Chen, B., Yu, Y., & Chen, S. (2022) · Medicine · doi:10.1097/md.0000000000031649 · Cited by 4
“[2] It was found that most patients with coronavirus disease 2019 (COVID-19) had taste disorders that improved with the control of COVID-19, but some patients still had remission of other clinical symptoms without improvement of taste.[3] Lechien et al[4] conducted a count of 417 patients with mild and moderate neocor…”
BackgroundPinedo, P. P., Mena, M. A. D., Vela, M. F., & Salazar‐Granara, A. (2022) · Revista del Cuerpo Médico Hospital Nacional Almanzor Aguinaga Asenjo · doi:10.35434/rcmhnaaa.2022.154.1545 · Cited by 5
Effects of COVID-19 on Sense of Smell: Human Factors/Ergonomics Considerations
Cameron, E. L., Møller, P., & Karn, K. S. (2021) · Human Factors The Journal of the Human Factors and Ergonomics Society · doi:10.1177/0018720821990162 · Cited by 6
“Most of the data reported thus far come from self- report (e.g., Bagheri et al., 2020; Giacomelli et al., 2020; Lechien et al., 2020; Parma et al., 2020; Qiu et al., 2020; Speth et al., 2020; Yan et al., 2020),”
BackgroundArrar, M., Belloli, L. M. L., Bianco, A. M., Boechi, L., Castro, R., Durán, G., Etchenique, R., Fernandez, N. B., Ferrer, L., Garbervetsky, D., et al. (2021) · Science Reviews - from the end of the world · doi:10.52712/sciencereviews.v2i2.38 · Cited by 4
Fernandez, I. J., Molinari, G., Federici, G., Silvestri, M., Corso, E. D., Presutti, L., Alicandri-Ciufelli, M., & Lucidi, D. (2021) · The Journal of Laryngology & Otology · doi:10.1017/s0022215121004047 · Cited by 4
Phenonizer: A fine-grained phenotypic named entity recognizer for Chinese clinical texts
Zou, Q., Yang, K., Chang, K., Zhang, X., Li, X., & Zhou, X. (2021) · IEEE International Conference on Bioinformatics and Biomedicine (BIBM) · doi:10.1109/bibm52615.2021.9669766 · Cited by 4
Olfactory nerve: from ugly duckling to swan
Mermelstein, S., Pereira, V. E. R., Serrano, P. D. L., Pastor, R. A. D. C. A., & Araujo, A. Q. C. (2022) · Arquivos de Neuro-Psiquiatria · doi:10.1590/0004-282x-anp-2020-0529 · Cited by 4
Self-reported Smell and Taste Disorders in Patients With COVID-19: A Japanese Single-center Study
Yamamoto, K., Fujiya, Y., Kuronuma, K., Ogasawara, N., Ohkuni, T., Yokota, S., Takahashi, S., & Takano, K. (2022) · In Vivo · doi:10.21873/invivo.12781 · Cited by 5
Gustatory dysfunction and oral ulceration in COVID-19 patients: A cross sectional study
Hans, V. M., Hans, M., Kahlon, N., Sagar, M., Pandey, A., & Das, A. (2022) · Dental Research Journal · doi:10.4103/1735-3327.346401 · Cited by 4
“[18,19] Multiple research works have demonstrated very high prevalence of taste dysfunction which are in line with our results.[20,21]”
ResultMuniz, P. R., Simão, J., Nunes, R. B., Campos, H. L. M., Santos, N. Q., Ninke, A., & Lemos, J. T. (2022) · Sensing and Bio-Sensing Research · doi:10.1016/j.sbsr.2022.100513 · Cited by 4
AlEnazi, A. S., Alharbi, M. A., Althomaly, D. H., Ashoor, M. M., Alwazzeh, M. J., Halawani, R. T., Buohliqah, L. A., & Telmesani, L. M. (2023) · Annals of Medicine and Surgery · doi:10.1097/ms9.0000000000001311 · Cited by 4
“This rate was more consistent with the results from Middle East , Europe and North America [3,4,6,40,41] .”
BackgroundResultInfluentialMedical Students' Awareness of Smell Loss as a Predictor for Coronavirus Disease 2019
Aldrees, T., Almatrafi, S., Aldriweesh, T., Mokhatrish, M., Salamh, A. F., & Alkholaiwi, F. (2020) · Frontiers in Public Health · doi:10.3389/fpubh.2020.597897 · Cited by 4
“Patients with a combination of anosmia and flu-like symptoms have been reported to be up to 10 times more likely to test positive for COVID-19 than if this combination is not present (11, 12).”
BackgroundA Rapid Olfactory Test as a Potential Screening Tool for COVID-19
Said, M., Davis, P. J., Davis, S., Smart, K. H., Davis, S., & Yan, C. H. (2021) · JAMA Otolaryngology–Head & Neck Surgery · doi:10.1001/jamaoto.2021.1456 · Cited by 4
Self-citationInciarte, A., Cardozo, C., Chumbita, M., Alcubilla, P., Torres, B., Cordón, A. G., Rico, V., Agüero, D. L., García-Pouton, N., Hernández‐Meneses, M., et al. (2021) · BMJ Open · doi:10.1136/bmjopen-2020-040775 · Cited by 4
Shaikhain, T. A., Al-Husayni, F., Bukhari, G., Alhawsa, B., Shalabi, N., Munshi, A., Saati, A., Neyazi, A., Alshehri, A., & Alzahrani, M. (2021) · SAGE Open Medicine · doi:10.1177/20503121211052421 · Cited by 4
Koparal, M., & Yılmazer, C. (2021) · Journal of the American Academy of Audiology · doi:10.1055/s-0041-1730960 · Cited by 5
The diagnostic accuracy of RT-PCR from self-collected saliva versus nasopharyngeal sampling
Kim, D. H., Basurrah, M. A., Han, J. H., Kim, S. W., & Hwang, S. H. (2022) · Saudi Medical Journal · doi:10.15537/smj.2022.43.1.20210743 · Cited by 4
Overdevest, J. B., Irace, A. L., Mazzanti, V., Oh, E. J., Joseph, P. V., Devanand, D. P., Bitan, Z. C., Hod, E. A., Gudis, D. A., & Chiuzan, C. C. (2022) · PLoS ONE · doi:10.1371/journal.pone.0274611 · Cited by 4
“Prior reports demonstrate an opportunity to leverage smell and taste alteration to predict diagnosis of COVID-19 [1, 36, 37].”
BackgroundSmell and Taste Abnormalities due to COVID-19
Al-Any, R. M. (2020) · Al- Anbar Medical Journal · doi:10.33091/amj.2020.170924 · Cited by 4
Vitamina D e doenças infectocontagiosas na pandemia da COVID-19
Silvino, V. O., Pereira, M. M. L., de Moura, R. C., Batista, M. C. C., Rosa, B. V., de Moura, E. H., Martins, M. D. C. D. C. E., & dos Santos, M. A. P. (2020) · Research Society and Development · doi:10.33448/rsd-v9i7.4614 · Cited by 3
Garcés-Villalá, M. Á., Nollen, J. A., Rico, S. D., Quiroga, G. A. C., Calvo‐Guirado, J. L., & RIOS, G. O. A. D. L. (2020) · Journal of Health Science and Prevention · doi:10.29080/jhsp.v4i2.375 · Cited by 4
Dight, T., & Gormley, M. J. (2021) · Frontiers in Built Environment · doi:10.3389/fbuil.2021.641745 · Cited by 5
Olfactory sensory evaluation in newborn children of women infected with COVID-19 during pregnancy
Costa, K., Ribeiro, L. M., Jesus, J. D., Costa, K., Fernandes, G. M., Spilski, J., Lachmann, T., & Tristão, R. M. (2021) · Journal of Human Growth and Development · doi:10.36311/jhgd.v31.11341 · Cited by 4
Evaluation of taste and smell disorders in pediatric COVID-19 Cases
Elmas, B., Çavdaroğlu, P. D., Orhan, M. F., Ay, G., Caner, İ., Tarım, A., Ateş, Ö. F., & Toptan, H. (2021) · Revista da Associação Médica Brasileira · doi:10.1590/1806-9282.20200547 · Cited by 4
Comment on: Oral Manifestation of COVID-19 as an inaugural symptom?
Riad, A., & Gomaa, M. (2020) · Journal of Oral Medicine and Oral Surgery · doi:10.1051/mbcb/2020020 · Cited by 4
“hypothesized that mild cases are attributed to nasal-centric viral spread that results in a high percentage of anosmia and amblygeustia occurrence, while severe cases are attributed to a more pulmonary-centric viral infection that leads to less experience of sensory malfunction [5].”
Valdés, A. J. B., Padrón‐González, A. A., & Archer-Jiménez, J. (2020) · Preprints.org · doi:10.20944/preprints202012.0663.v1 · Cited by 4
“In United States A, a clinical study described that smell and taste impairments were strongly associated with COVID‐19[2] and Centers for Disease Control and Prevention added ‘loss of taste or smell’ as one of six new symptoms of COVID‐ 19 on their advisory page on April 27, 2020[3].”
BackgroundSamaranayake, L. P., Fakhruddin, K. S., & Panduwawala, C. (2020) · Preprints.org · doi:10.20944/preprints202006.0198.v1 · Cited by 3
COVID-19 related olfactory dysfunction prevalence and natural history in ambulatory patients
Bacon, D. R., Onuorah, P. C., Murr, A., Wiesen, C., Oakes, J., Thorp, B. D., Zanation, A. M., Ebert, C. S., Wohl, D. A., Senior, B. A., et al. (2021) · Rhinology online · doi:10.4193/rhinol/21.034 · Cited by 3
Olfactory Dysfunction during the COVID-19 Era
Alyahya, K. A., Alarfaj, A. A., Al-Zahir, B. Z., Alhelal, F. M., Sultan, W. A. A., Almulhim, I. M., & Alhamam, A. K. (2023) · Saudi Journal of Otorhinolaryngology Head and Neck Surgery · doi:10.4103/sjoh.sjoh_60_22 · Cited by 3
Anatomical perspective on the loss of smell and taste sensation in SARS-CoV-2 infection
Kilroy, D., & Kumar, A. H. S. (2020) · Anatomy (International Journal of Experimental and Clinical Anatomy) · doi:10.2399/ana.20.049 · Cited by 3
“Considering the consistency in the COVID-19 symptoms observed, fever together with chemosensory impairment (anosmia and/or ageusia) can be used as an early detection parameters to rapidly and reliably identify and isolate patients with COVID-19.”
BackgroundResultInfluentialOlfactory nerve: from ugly duckling to swan
Mermelstein, S., Pereira, V. E. R., Serrano, P. D. L., Pastor, R. A. D. C. A., & Araújo, A. (2022) · LA Referencia (Red Federada de Repositorios Institucionales de Publicaciones Científicas) · Cited by 3
Quiroz-Ruiz, H. R., Effio, P. J. C., Vértiz-Osores, J. J., & Bazán-Mayra, J. E. (2022) · Revista chilena de infectología · doi:10.4067/s0716-10182022000100035 · Cited by 3
Kim, J., & Young, G. S. (2023) · Seminars in Neurology · doi:10.1055/s-0043-1767771 · Cited by 3
Hunter, S., Zola, A. R., Ho, E., Kallen, M. A., Adjei-Danquah, E., Achenbach, C. J., Smith, G. R., Gershon, R. C., Reed, D. R., Schalet, B. D., et al. (2024) · Frontiers in Public Health · doi:10.3389/fpubh.2024.1322797 · Cited by 3
How does COVID-19 affect the brain?
Aamodt, A. H., Harbo, H. F., Eldøen, G., Barratt‐Due, A., & Aukrust, P. (2020) · Tidsskrift for Den norske legeforening · doi:10.4045/tidsskr.20.0444 · Cited by 3
Riechstörungen bei COVID-19 – aktueller Wissensstand
Otte, M. S., Klußmann, J. P., & Lüers, J.-C. (2020) · Laryngo-Rhino-Otologie · doi:10.1055/a-1183-4835 · Cited by 3
“Von 59 positiv auf SARS-CoV-2 getesteten Teilnehmern gaben 68 % eine Riechstörung an, im Gegensatz zu nur 17 % bei 203 negativ Getesteten [7].”
BackgroundBasic sciences applied to Bioengineering and its relations with the COVID-19 Pandemic
Pomini, K. T., Dias, J. A., Serva, F. M., Reis, C. H. B., Spressão, D. R. M. S., Félix, M., Eleutério, R. G., Pereira, E. D. S. B. M., Buchaim, D. V., & Buchaim, R. L. (2020) · International Journal of Advanced Engineering Research and Science · doi:10.22161/ijaers.712.40 · Cited by 3
“The most recurrent symptoms already reported are severe acute respiratory infection, which causes great difficulty in breathing, fever, cough, dyspnoea, malaise, myalgia, gastrointestinal disorders and neurological complications, the most common of which are decreased ability to taste or ageusia , and low olfactory se…”
BackgroundOlfactory Dysfunction: A Clinical Marker of COVID-19
Pokharel, A. (2021) · Journal of Nepal Medical Association · doi:10.31729/jnma.5658 · Cited by 4
Sagar, P., Kumar, R., Fatima, R., Bollu, S., Mehmi, N., Subagar, A. S., & Thakar, A. (2021) · Indian Journal of Otolaryngology and Head & Neck Surgery · doi:10.1007/s12070-021-02551-7 · Cited by 3
The incidence and pathophysiology of neurological symptoms in COVID-19
Litvinenko, I., Odinak, M. M., Tsygan, N. V., & Ryabtsev, A. V. (2021) · Russian Military Medical Academy Reports · doi:10.17816/rmmar83617 · Cited by 3
“При COVID-19 возможной причиной высокой частоты нарушений обоняния и вкусового восприятия является катаральное воспаление, однако при других острых респираторных заболеваниях такой сильной связи не прослеживается [4].”
Clinical Epidemiology of Coronavirus Disease 2019:Defined on Current Research
Zhang, F., & Hughes, C. L. (2020) · Global Clinical and Translational Research · doi:10.36316/gcatr.02.0032 · Cited by 3
Sheen, F., Tan, V. W. K., Haldar, S., Sengupta, S., Allen, D. M., Somani, J., Chen, H. Y., Tambyah, P. A., & Forde, C. G. (2020) · JMIR Research Protocols · doi:10.2196/24797 · Cited by 3
“Recent self-report questionnaire data from many countries highlights an association between sudden onset smell and taste loss and COVID-19 infection, with reported incidences of changes in sensory acuity ranging from 11% to >60% [7-13].”
Radio-laboratory findings in COVID-19 anosmia patients: a single-center experience
Algarf, T. M., Youssef, M. A., Elshazly, M. I., Ismail, M. S., Hasswa, M. K., & Mousa, M. S. (2021) · The Egyptian Journal of Otolaryngology · doi:10.1186/s43163-021-00133-6 · Cited by 3
Dabhekar, S., Basagoudanavar, S. H., Bidkar, V. G., Prathipati, K., Akkilagunta, S., Rathod, B. S., & Deepa, G. (2022) · Cureus · doi:10.7759/cureus.22186 · Cited by 3
Yepes, M. (2022) · Current Drug Targets · doi:10.2174/1389450123666220919123029 · Cited by 4
Seroprevalence of SARS-CoV-2: Insights into the epidemiology of the pandemic
Ali, A., Waqar, M., Akram, A., Rafique, S., Rehman, G., Idrees, M., Halim, S. A., Waqas, M. S., Uddin, J., Gojayev, A., et al. (2023) · Journal of Infection and Public Health · doi:10.1016/j.jiph.2023.05.036 · Cited by 3
Smell Disorder Could Warn Head and Neck Surgeons for Diagnosis of COVID-19
Abdel‐Aziz, M. (2020) · Journal of Craniofacial Surgery · doi:10.1097/scs.0000000000006844 · Cited by 3
Case Report: A Nasopharyngeal Cancer Patient Got COVID-19 During Radiochemotherapy in Wuhan
Qiu, W., Yi, F., Ren, X., Li, Z., Wang, D., & Wang, N. (2020) · Frontiers in Oncology · doi:10.3389/fonc.2020.01755 · Cited by 3
“In this case, typical symptoms of COVID-19 such as fever, dry cough, and fatigue developed, but not loss of smell or taste, a symptom recently reported in more than 60% of COVID-19 patients (5, 6).”
BackgroundMangia, L. R. L., Soares, M. B., de Souza, T. S. C., Masi, R. D. J. D., Scarabotto, P. C., & Hamerschmidt, R. D. A. (2021) · Auris Nasus Larynx · doi:10.1016/j.anl.2021.01.015 · Cited by 3
Utility of Olfactory test as screening tool for COVID-19: A pilot studyPreprint
Khare, P., Chander, A. M., Agrawal, K., Jayant, S. S., Mukherjee, S., Yadav, K., Gupta, R., Chaudhary, S., Srivastava, S., Muralidharan, S., et al. (2020) · medRxiv · doi:10.1101/2020.09.03.20187294 · Cited by 3
Neurological infections in 2020: COVID-19 takes centre stage
Fredrich, S., Greenberg, B. M., & Hatanpaa, K. J. (2020) · The Lancet Neurology · doi:10.1016/s1474-4422(20)30451-8 · Cited by 3
International Delphi Expert Consensus on Safe Return to Surgical and Endoscopic Practice
Asbun, H. J., Hilal, M. A., Kunzler, F., Asbun, D., Bonjer, H. J., Conlon, K. C., Demartines, N., Feldman, L. S., Morales‐Conde, S., Pietrabissa, A., et al. (2020) · Annals of Surgery · doi:10.1097/sla.0000000000004674 · Cited by 9
Recovery of Parosmia Preferentially Influences Longitudinal Improvement of Quality of Life in C19OD
Saak, T. M., Tervo, J. P., Vilarello, B. J., Jacobson, P. T., Caruana, F. F., Gallagher, L. W., Gudis, D. A., Devanand, D. P., & Overdevest, J. B. (2026) · International Forum of Allergy & Rhinology · doi:10.1002/alr.70149 · Cited by 2
Implications for border containment strategies when COVID-19 presents atypically
Teo, W. (2020) · Public Health · doi:10.1016/j.puhe.2020.07.019 · Cited by 2
Advances in Intelligent Based Internet of Medical Things (IoMT) for COVID-19: Olfactory Disorders
Brindha, V. E., & Mary, X. A. (2020) · Studies in computational intelligence · doi:10.1007/978-981-15-8534-0_19 · Cited by 2
Costa, B. S., Moraes, G. D. A., Borges, C. T., Meneguzzo, D. T., & Corrêa, V. D. O. S. (2021) · Brazilian Journal of Health Review · doi:10.34119/bjhrv4n2-117 · Cited by 2
Olfactory testing as COVID-19 screening in school children; A prospective cross-sectional study
Gitomer, S. A., Tholen, K., Pickett, K. L., Mistry, R. D., Beswick, D. M., Kaar, J. L., & Herrmann, B. W. (2022) · PLoS ONE · doi:10.1371/journal.pone.0277882 · Cited by 2
Savoy, M., Kopp, B., Chaouch, A., Cohidon, C., Gouveia, A., Lombardo, P., Maeder, M., Payot, S., Perdrix, J., Schwarz, J., et al. (2023) · Infectious Disease Reports · doi:10.3390/idr15010012 · Cited by 2
“Whereas sore throat was previously described as negatively associated with RT-PCR test results [4,9,16,29,30], our results reported no difference between groups.”
BackgroundResultAmino Acid Metabolism in Leukocytes Showing In Vitro IgG Memory from SARS-CoV2-Infected Patients
Fanelli, G., Lelli, V., Rinalducci, S., & Timperio, A. M. (2024) · Diseases · doi:10.3390/diseases12030043 · Cited by 2
“People who have risk factors, such as advanced age, smoking, and concomitant diseases (diabetes, hypertension, cardiovascular disease, obesity, chronic lung disease, kidney disease) are more susceptible to severe acute respiratory syndrome (SARS) [13].”
BackgroundUpper Respiratory Symptoms as Long COVID: Insight from a Multicenter Cohort Study
Okada, M., Ishida, N., Kanzaki, S., Kawada, I., Nagashima, K., Terai, H., Hiruma, G., Namkoong, H., Asakura, T., Masaki, K., et al. (2024) · OTO Open · doi:10.1002/oto2.120 · Cited by 2
Diaconu, I. E. (2024) · The Medical-Surgical Journal · doi:10.22551/msj.2024.01.03 · Cited by 2
Subjective Versus Psychophysical Measures of Chemosensory Alterations Following COVID-19
Vilarello, B. J., Jacobson, P. T., Snyder, C. J., Choo, T.-H. J., Gallagher, L. W., Caruana, F. F., Tervo, J. P., Gary, J. B., Saak, T. M., Gudis, D. A., et al. (2024) · ORL · doi:10.1159/000539378 · Cited by 2
“Early reports associating olfactory loss with acute COVID-19 [6, 7] have evolved into tracking the prevalence of persistent olfactory dysfunction (OD) [8].”
SAFER PRACTICES in the COVID-19 pandemic
Silverston, P. P. (2020) · Practice Nursing · doi:10.12968/pnur.2020.31.5.194 · Cited by 2
Lehmann, J., Giesinger, J. M., Rumpold, G., Borena, W., Knabl, L., Falkensammer, B., Ower, C., Sacher, M., von Laer, D., Sperner‐Unterweger, B., et al. (2021) · Epidemiology and Infection · doi:10.1017/s0950268821000418 · Cited by 2
“This conforms with other studies in which the alterations in (or sometimes loss of) smell or taste were a key symptom to distinguish patients with flu-like symptoms from patients with COVID-19 [6,7].”
ResultInfluentialClinical, laboratory and radiological features and outcomes of moderate to severe COVID-19 patients
Nehara, H. R., Agrawal, S., Chhimpa, A. R., Sunil, I., Arakeri, A., & Sirohi, P. (2021) · Journal of Acute Disease · doi:10.4103/2221-6189.312154 · Cited by 2
Chest CT features in COVID-19 patients
Taghavi, M., Shokri, A., Niloofar, P., Poorbarat, S., Mollazadeh, S., & Milani, H. (2021) · Journal of Acute Disease · doi:10.4103/2221-6189.326907 · Cited by 2
Pang, K. W., Tham, S. Y. Y., & Ng, L. S. (2021) · Life · doi:10.3390/life11121315 · Cited by 2
“Alizadehsani [142] Altman [143] Beltrán-Corbellini [176] Bénézit [34] Bidkar [139] Boudjema [140] Carignan [177] Chas [144] Chen [149] Cho [178] Dawson [179] Dixon [180] Dreyer [150] Elimian [181] Fistera [145] Ganz-Lord [146] Gibbons [151] Gurrola [182] Izquierdo-Domínguez [183] Jeyashree (1) [141] Jeyashree (2) [141…”
BackgroundJungbauer, F., Gerhards, C., Thiaucourt, M., Behnes, M., Rotter, N., Schell, A., Haselmann, V., Neumaier, M., & Kittel, M. (2022) · Life · doi:10.3390/life12070968 · Cited by 2
Considerations for Pregnant Dental and Health Care Workers amid COVID-19
Mann, A., Dahiya, A., Souza, L. C., & Letra, A. (2020) · JDR Clinical & Translational Research · doi:10.1177/2380084420952747 · Cited by 2
“More recently, chemosensory dysfunction leading to loss of taste and smell sensation, and cutaneous reactions ranging from erythematous rash to varicellalike vesicular lesions have been reported as prominent characteristics (Marzano et al. 2020; Yan et al. 2020).”
BackgroundAspectos epidemiológicos, clínicos e olfatórios de pacientes com COVID-19
Seto, I. I. C., Koury, G. V. H., Gomes, V. C. A., Silva, L. F. E., Umbelino, A. M., Yamaguchi, C. T., & Ferreira, D. B. (2021) · Revista Eletrônica Acervo Saúde · doi:10.25248/reas.e6348.2021 · Cited by 2
Bohórquez-Rivero, J., Sáenz-López, J., Villamizar, K. E. T., & Sáenz, R. C. G. (2021) · Revista Ciencias Biomédicas · doi:10.32997/rcb-2021-3235 · Cited by 2
Rehabilitation challenges in COVID-19 induced acute polyradiculoneuropathies
Stănescu, I., Bulboacă, A., Cordos, A. I., Fodor, D. M., & Bulboacă, A. E. (2021) · Balneo and PRM Research Journal · doi:10.12680/balneo.2021.426 · Cited by 2
“incidences, ranging from 48 to 98% for olfactory dysfunction and to 71 to 88% for ageusia (7,8, 9, 10).”
BackgroundRegalado-Go, J. A., Tayam, M. M., Santos, R., & Gelera, J. (2021) · Philippine Journal of Otolaryngology Head and Neck Surgery · doi:10.32412/pjohns.v36i1.1649 · Cited by 3
Tsygan, N. V., Trashkov, A. P., Ryabtsev, A. V., Yakovleva, V. A., Konevega, A. L., Vasiliev, A. G., Vn, T., Odinak, M. M., & Litvinenko, I. (2021) · General Reanimatology · doi:10.15360/1813-9779-2021-3-65-77 · Cited by 2
“При COVID-19 возможной причиной высокой частоты нарушений обоняния и вкусового восприятия может являться катаральное воспаление, однако при других острых респираторных заболеваниях настолько сильной связи не прослеживается [4, 22].”
BackgroundBiswas, S., Chakraborty, C., Chawla, R., Paul, D., Sen, D., Sarkar, N., & Mukherjee, M. (2021) · International Journal of Statistics in Medical Research · doi:10.6000/1929-6029.2021.10.17 · Cited by 2
Speth, M. M., Speth, U. S., Sedaghat, A. R., & Hummel, T. R. (2022) · HNO · doi:10.1007/s00106-021-01132-y · Cited by 2
“Die Prävalenz wird in der Literatur zwischen 19 und 86% angegeben [35, 36, 37, 38, 39, 40].”
BackgroundDelgado‐Losada, M. L., Bouhaben, J., Ruiz-Huerta, C., Canto, M. V., & Delgado‐Lima, A. H. (2022) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph19095777 · Cited by 2
Manhas, M., Koul, D., Kalsotra, G., Manhas, A., Kalsotra, P., Kumar, P., Bhat, A., Gupta, A., & Saraf, A. (2022) · International Archives of Otorhinolaryngology · doi:10.1055/s-0042-1743274 · Cited by 2
“Our fi ndings of smell and taste disturbances (60.8% and 59.6%, respectively) were similar to those of Valeria et al., 23 and Yan et al. 24 An European multi-centric study reported high percentages for both smell and taste disorders, with a female prevalence (85.6% and 88.0%, respectively).”
ResultInfluentialHafez, W., Abdelshakor, M., Gador, M., Abdelli, I., & Ahmed, S. (2022) · Tropical Medicine and Infectious Disease · doi:10.3390/tropicalmed7070115 · Cited by 2
“Moreover, multiple observational studies have revealed that loss of taste and/or smell is a prevalent symptom among mild-tomoderate COVID-19 patients, implying that olfactory/gustatory dysfunction could be a useful screening tool for early case identification and isolation [6,7,21].”
BackgroundUtomo, N. P., & Iswarini, A. D. (2022) · The Egyptian Journal of Otolaryngology · doi:10.1186/s43163-022-00271-5 · Cited by 2
“One symptom allegedly becomes the most prevalent of all chemosensory symptoms, olfactory dysfunction [1].”
BackgroundPerepi, R., Santhi, K., Saraswathi, R., & Bég, O. A. (2022) · Computer Methods in Biomechanics and Biomedical Engineering Imaging & Visualization · doi:10.1080/21681163.2022.2120829 · Cited by 2
Post-Viral Olfactory Loss: What We Learned from the SARS-CoV-2 Pandemic
Vaira, L. A., Deiana, G., Maglitto, F., & Salzano, G. (2022) · Life · doi:10.3390/life12111868 · Cited by 2
“During the pandemic, many researchers bravely evaluated patients within isolation departments, and for the first time, we were able to estimate the prevalence of olfactory dysfunctions during an infection [16–18] and study the diagnostic [19,20] and prognostic value of these symptoms [21–23].”
BackgroundCOVID-19 w otorynolaryngologii
Męczkowska, K., & Niedzielski, A. (2020) · Wiedza Medyczna · doi:10.36553/wm.49 · Cited by 2
“Stwierdzono, że zaburzenia węchu i smaku znacznie częściej występowały u pacjentów z wynikiem pozytywnym (68 i 71%) niż negatywnym (16 i 17%) (23).”
Neurological Manifestations of COVID-19 (Severe Acute Respiratory Syndrome Coronavirus 2)
Suri, V., Suri, K., Jain, S., & Suri, K. (2020) · Apollo Medicine · doi:10.4103/am.am_63_20 · Cited by 2
“[15] Another report from a large cohort of 10,069 patients from Iran, employing a online questionnaire-based survey, observed an incidence of anosmia/hyposmia in 48.2% of respondents, whereas 83.38% had loss or reduced sense of taste.”
InfluentialSubjective Smell Assessment as An Office-based Rapid Procedure In COVID-19 Era
Abdel‐Aziz, M., Abdel‐Aziz, N. M., Abdel‐Aziz, D. M., & Azab, N. A. (2020) · Journal of Craniofacial Surgery · doi:10.1097/scs.0000000000007245 · Cited by 2
“In a USA study carried out on patients with influenza-like symptoms, loss of smell was found in 68% of COVID-19-positive patients compared to 16% of COVID-19 negative subjects.(4) A multicenter study carried out in 4 European countries showed smell disorder in 85.”
ResultMattiuzzi, C., & Lippi, G. (2020) · Acta bio-medica dell'Ateneo parmense/Acta biomedica · doi:10.23750/abm.v92i1.11070 · Cited by 2
“Mountain View, CA, US), with the search term “COVID-19” together with the most common symptoms reported in patients with SARSCoV-2 infection, especially in the US, as summarized in Table 1 (4,5).”
BackgroundNeurological Manifestations of COVID-19
Farhat, S. M. (2021) · Life and Science · doi:10.37185/lns.1.1.162 · Cited by 2
Fasunla, A. J., Thairu, Y., Salami, H., & Ibekwe, T. (2021) · PubMed Central · Cited by 2
Speth, M. M., Speth, U. S., Sedaghat, A. R., & Hummel, T. R. (2022) · DGNeurologie · doi:10.1007/s42451-022-00434-x · Cited by 2
Covid-19 and Other Viruses in Brazil: Can the New Pandemic Influence Epidemiological Records?Preprint
Fernandes, H. S. (2020) · Preprints.org · doi:10.20944/preprints202005.0138.v1 · Cited by 2
The usefulness of a quantitative olfactory test for the detection of COVID-19Preprint
Lessa, M. A., Cotta-Pereira, S. M., Ferreira, F. A., Castiñeiras, T. M. P. P., Galliez, R. M., Faffe, D. S., Leitão, I. D. C., Mariani, D., Nascimento, É. R. D. S., Lessa, F., et al. (2021) · medRxiv · doi:10.1101/2021.01.20.21250173 · Cited by 2
Metadata
- Authors
- Yan, C. H., Faraji, F., Prajapati, D. P., Boone, C. E., & DeConde, A. S.
- Affiliations
- UC San Diego Health System (US)
- Corresponding author
- Yan, Carol H.
- Venue
- International Forum of Allergy & Rhinology
- Publisher
- Wiley
- Published
- 2020-06
- Volume
- 10
- Issue
- 7
- Pages
- 806-813
- ISSN
- 2042-6976 (ISSN-L)
- 2042-6984
- PMC
- PMC7262089
- OpenAlex
- W3015631092
- Cited by
- 754
- References
- 13
- Citations by year
- 2026: 7 · 2025: 7 · 2024: 19 · 2023: 60 · 2022: 94 · 2021: 248 · 2020: 317
- FWCI
- 63.31
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- International Forum of Allergy & Rhinology (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- eScholarship (California Digital Library) (submittedVersion)
- Funders
- National Center for Advancing Translational Sciences (UL1TR001442)
- Topics
- Life Sciences › Neuroscience › Sensory Systems › Olfactory and Sensory Function Studies
- Health Sciences › Medicine › Infectious Diseases › COVID-19 Clinical Research Studies
- Health Sciences › Medicine › Dermatology › Dermatological and COVID-19 studies
- Keywords
- COVID-19 pandemic, SARS-CoV-2, anosmia, ageusia, chemosensory dysfunction, flu-like symptoms, subclinical symptoms, symptom screening, sore throat, symptom resolution, virus transmission, asymptomatic transmission, outpatients, patient-reported symptoms, COVID-19 testing, COVID-19 isolation, COVID-19 recovery
- MeSH terms
- Betacoronavirus, COVID-19, SARS-CoV-2, Adolescent, Adult, Aged, Aged, 80 and over, Olfaction Disorders, Cross-Sectional Studies, Female, Humans, Male, Middle Aged, Pneumonia, Viral, Taste Disorders, Prevalence, Coronavirus Infections, Young Adult, Pandemics
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
