White matter hyperintensities in Alzheimer's disease: Beyond vascular contribution

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White matter hyperintensities are a core feature of Alzheimer’s disease: evidence from the dominantly inherited Alzheimer network

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Microglial activation and tau propagate jointly across Braak stages

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Inflammation and cerebral small vessel disease: A systematic review

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White matter hyperintensities in vascular contributions to cognitive impairment and dementia (VCID): Knowledge gaps and opportunities

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Extent and distribution of white matter hyperintensities in normal aging, MCI, and AD

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Heterogeneity in age-related white matter changes

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Heterogeneity of white matter hyperintensities in Alzheimer's disease: post-mortem quantitative MRI and neuropathology

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Parietal white matter lesions in Alzheimer’s disease are associated with cortical neurodegenerative pathology, but not with small vessel disease

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Reconsidering harbingers of dementia: progression of parietal lobe white matter hyperintensities predicts Alzheimer's disease incidence

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White matter hyperintensities: relationship to amyloid and tau burden

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Regional White Matter Hyperintensity Volume, Not Hippocampal Atrophy, Predicts Incident Alzheimer Disease in the Community

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White-matter integrity on DTI and the pathologic staging of Alzheimer’s disease

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Leuko-Araiosis: An Ancient Term for a New Problem

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Multiethnic Genome-Wide Association Study of Cerebral White Matter Hyperintensities on MRI

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White matter hyperintensity topography in Alzheimer's disease and links to cognition

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Cortical tau load is associated with white matter hyperintensities

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Could Wallerian degeneration contribute to "leuko-araiosis" in subjects free of any vascular disorder?

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White matter lesions

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Contemplating Alzheimer’s Disease and the Contribution of White Matter Hyperintensities

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Associations between amyloid β and white matter hyperintensities: A systematic review

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The effect of white matter hyperintensities on neurodegeneration in mild cognitive impairment

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White matter hyperintensities and the mediating role of cerebral amyloid angiopathy in dominantly-inherited Alzheimer’s disease

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Axonal Degeneration in AD: The Contribution of Aβ and Tau

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Frontal white matter lesions in Alzheimer’s disease are associated with both small vessel disease and AD-associated cortical pathology

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Cerebrovascular disease promotes tau pathology in Alzheimer’s disease

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APOE ε4 and risk for Alzheimer's disease: Do regionally distributed white matter hyperintensities play a role?

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Brain amyloid and vascular risk are related to distinct white matter hyperintensity patterns

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White matter hyperintensities are associated with grey matter atrophy and cognitive decline in Alzheimer's disease and frontotemporal dementia

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Spatial patterns of white matter hyperintensities associated with Alzheimer’s disease risk factors in a cognitively healthy middle-aged cohort

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Cerebral amyloid burden is associated with white matter hyperintensity location in specific posterior white matter regions

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Alzheimer-Related Cerebrovascular Disease in Down Syndrome

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Clinical and biomarker changes in presymptomatic genetic frontotemporal dementia

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Topographic patterns of white matter hyperintensities are associated with multimodal neuroimaging biomarkers of Alzheimer’s disease

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Serum IL‐8 is a marker of white‐matter hyperintensities in patients with Alzheimer's disease

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White matter hyperintensities in autopsy-confirmed frontotemporal lobar degeneration and Alzheimer’s disease

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Bundle-specific associations between white matter microstructure and Aβ and tau pathology in preclinical Alzheimer’s disease

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CSF amyloid is a consistent predictor of white matter hyperintensities across the disease course from aging to Alzheimer's disease

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CSF β-amyloid and white matter damage: a new perspective on Alzheimer’s disease

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Plasma soluble TREM2 is associated with white matter lesions independent of amyloid and tau

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Clinical and biological correlates of white matter hyperintensities in patients with behavioral-variant frontotemporal dementia and Alzheimer disease

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Hyperintensity of the corticospinal tract on FLAIR: A simple and sensitive objective upper motor neuron degeneration marker in clinically verified amyotrophic lateral sclerosis

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White matter hyperintensity microstructure in amyloid dysmetabolism

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White Matter Hyperintensities in Alzheimer’s Disease: A Lesion Probability Mapping Study

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Association Between Antemortem FLAIR White Matter Hyperintensities and Neuropathology in Brain Donors Exposed to Repetitive Head Impacts

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Regional white matter hyperintensities in posterior cortical atrophy and logopenic progressive aphasia

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Lipidome disruption in Alzheimer’s disease brain: detection, pathological mechanisms, and therapeutic implications

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Regional cortical thinning, demyelination and iron loss in cerebral small vessel disease

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Linking white matter hyperintensities to regional cortical thinning, amyloid deposition, and synaptic density loss in Alzheimer's disease

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Subclinical epileptiform activity in the Alzheimer continuum: association with disease, cognition and detection method

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Can white matter hyperintensities based Fazekas visual assessment scales inform about Alzheimer’s disease pathology in the population?

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Intracranial arteriosclerosis and the risk of dementia: A population‐based cohort study

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Choroid plexus free‐water correlates with glymphatic function in Alzheimer's disease

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Association of white matter hyperintensities with cognitive decline and neurodegeneration

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Cerebrovascular disease is associated with Alzheimer’s plasma biomarker concentrations in adults with Down syndrome

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The Energetic Collapse of the Alzheimer's Brain: Metabolic Inflexibility Across Cells and Networks

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Arterial hypertension and β-amyloid accumulation have spatially overlapping effects on posterior white matter hyperintensity volume: a cross-sectional study

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White matter hyperintensities and Alzheimer's disease: An alternative view of an alternative hypothesis

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DNA methylation age from peripheral blood predicts progression to Alzheimer’s disease, white matter disease burden, and cortical atrophy

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Characterization of white matter hyperintensities in Down syndrome

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Alzheimer Disease, Vascular Disease, and Blood-Brain Barrier Permeability Biomarkers in Middle-Aged Adults

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The 2024 NIA-AA biological definition of Alzheimer’s disease: linking biomarkers to clinical practice

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White matter injury, plasma Alzheimer's disease, and neurodegenerative biomarkers on cognitive decline in community‐dwelling older adults: A 10‐year longitudinal study

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White matter fractional anisotropy decreases precede hyperintensities in Alzheimer’s disease

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Longitudinal evidence for a mutually reinforcing relationship between white matter hyperintensities and cortical thickness in cognitively unimpaired older adults

Bernal, J., Menze, I., Yakupov, R., Peters, O., Hellmann‐Regen, J., Freiesleben, S. D., Priller, J., Spruth, E. J., Altenstein, S., Schneider, A., et al. (2024) · Alzheimer s Research & Therapy · doi:10.1186/s13195-024-01606-5 · Cited by 17 · see citing works

The POINTER Imaging baseline cohort: Associations between multimodal neuroimaging biomarkers, cardiovascular health, and cognition

Harrison, T. M., Ward, T. J., Taggett, J. Z., Maillard, P., Lockhart, S. N., Jung, Y., Lovato, L., Koeppe, R. A., Jagust, W. J., Harvey, D. J., et al. (2024) · Alzheimer s & Dementia · doi:10.1002/alz.14399 · Cited by 16 · see citing works

Retinal microvascular alterations in Alzheimer's disease: Linking blood plasma biomarkers and cerebral small vessel pathology

Kwapong, W. R., Wu, N., Lin, W., Shen, J., Wang, Y., Qian, J., Wen, C., Luan, X., Liu, Y., Cheng, H., et al. (2025) · Alzheimer s & Dementia · doi:10.1002/alz.70745 · Cited by 16 · see citing works

Alzheimer's Disease Diagnosis Using Ensemble of Random Weighted Features and Fuzzy Least Square Twin Support Vector Machine

Sharma, R., Goel, T., Tanveer, M., & Al‐Dhaifallah, M. (2025) · IEEE Transactions on Emerging Topics in Computational Intelligence · doi:10.1109/tetci.2024.3523714 · Cited by 16 · see citing works

Multi-modal machine learning approach for early detection of neurodegenerative diseases leveraging brain MRI and wearable sensor data

Li, A., Lian, J., & Vardhanabhuti, V. (2025) · PLOS Digital Health · doi:10.1371/journal.pdig.0000795 · Cited by 15 · see citing works

APOE ε4–associated heterogeneity of neuroimaging biomarkers across the Alzheimer's disease continuum

Mares, J. A., Kumar, G., Sharma, A., Emrani, S., McIntire, L. B., Guo, J., Menon, V., Nuriel, T., & Initiative, A. D. N. (2024) · Alzheimer s & Dementia · doi:10.1002/alz.14392 · Cited by 14 · see citing works

Fazekas scale magnetic resonance imaging assessment in Alzheimer’s disease and primary age-related tauopathy

Quintas-Neves, M., Almeida, F., Gauthreaux, K. M., Teylan, M., Mock, C., Kukull, W. A., Crary, J. F., & Oliveira, T. G. (2024) · Neuroradiology · doi:10.1007/s00234-024-03464-2 · Cited by 14 · see citing works

Exploring white matter microstructural alterations in mild cognitive impairment: a multimodal diffusion MRI investigation utilizing diffusion kurtosis and free-water imaging

Nelson, M. R., Keeling, E. G., Stokes, A. M., & Bergamino, M. (2024) · Frontiers in Neuroscience · doi:10.3389/fnins.2024.1440653 · Cited by 13 · see citing works

Unraveling the transcriptomic landscape of brain vascular cells in dementia: A systematic review

Sewell, M. D. E., Fialova, N., & Montagne, A. (2025) · Alzheimer s & Dementia · doi:10.1002/alz.14512 · Cited by 11 · see citing works

Regional White Matter Hyperintensities Relate to Specific Cognitive Abilities in Older Adults Without Dementia

Membreno, R., Thomas, K. R., Calcetas, A. T., Edwards, L., Bordyug, M., Showell, M., Stanfill, M., Brenner, E. K., Walker, K. S., Rotblatt, L. J., et al. (2023) · Alzheimer Disease & Associated Disorders · doi:10.1097/wad.0000000000000585 · Cited by 11 · see citing works

Lower Retinal Arteriolar Density Is Associated With Higher Cerebral Small Vessel Disease Burden: An Optical Coherence Tomography Angiography Study

Cao, L., Wang, H., Hao, J., Kwapong, W. R., Xiong, Z., Wang, R., Ye, C., Zhao, Y., Wu, B., & Tao, W. (2025) · Brain and Behavior · doi:10.1002/brb3.70342 · Cited by 10 · see citing works

Longitudinal biomarker studies in human neuroimaging: capturing biological change of Alzheimer’s pathology

Fischer, L., Parker, D. M., Maboudian, S. A., Fonseca, C. S., Tato-Fernández, C., Annen, L., Arunachalam, P., Bacci, J. R., Barboure, M. C., Capelli, S., et al. (2025) · Alzheimer s Research & Therapy · doi:10.1186/s13195-025-01920-6 · Cited by 10 · see citing works

Small vessel cerebrovascular disease is associated with cognition in prospective Alzheimer’s clinical trial participants

Morales, C. D., Cotton‐Samuel, D., Lao, P. J., Chang, J. F., Pyne, J. D., Alshikho, M. J., Lippert, R. V., Bista, K. C., Hale, C., Edwards, N. C., et al. (2024) · Alzheimer s Research & Therapy · doi:10.1186/s13195-024-01395-x · Cited by 10 · see citing works

White Matter Hyperintensities and Microstructural Alterations in Contact Sport Athletes from Adolescence to Early Midlife

Brett, B. L., Klein, A. P., Vazirnia, P., Omidfar, S. A., Guskiewicz, K. M., McCrea, M., & Meier, T. B. (2024) · Journal of Neurotrauma · doi:10.1089/neu.2023.0609 · Cited by 10 · see citing works

Microstructural white matter injury contributes to cognitive decline: Besides amyloid and tau

Hu, H., Li, H., Gong, W., Huang, S., Fu, Y., Hu, H., Dong, Q., Cheng, W., Tan, L., Cui, M., et al. (2025) · The Journal of Prevention of Alzheimer s Disease · doi:10.1016/j.tjpad.2024.100037 · Cited by 10 · see citing works

Atrophy trajectories in Alzheimer’s disease: how sex matters

Inguanzo, A., Poulakis, K., Oltra, J., Maioli, S., Marseglia, A., Ferreira, D., Mohanty, R., Westman, E., & Initiative, A. D. N. (2025) · Alzheimer s Research & Therapy · doi:10.1186/s13195-025-01713-x · Cited by 10 · see citing works

Cerebrovascular disease drives Alzheimer plasma biomarker concentrations in adults with Down syndromePreprint

Edwards, N. C., Lao, P. J., Alshikho, M. J., Ericsson, O. M., Rizvi, B. M., Petersen, M. E., O’Bryant, S. E., Aguilar, L. F., Simoes, S., Mapstone, M. E., et al. (2023) · medRxiv · doi:10.1101/2023.11.28.23298693 · Cited by 10 · see citing works

Assessing cognitive impairment and disability in older adults through the lens of whole brain white matter patterns

Roh, H. W., Chauhan, N., Seo, S. W., Choi, S. H., Kim, E., Cho, S. H., Kim, B. C., Choi, J. W., An, Y., Park, B., et al. (2024) · Alzheimer s & Dementia · doi:10.1002/alz.14094 · Cited by 7 · see citing works

Assessing the Global Impact of Brain Small Vessel Disease on Cognition: The Multi‐Ethnic Study of Atherosclerosis

Charisis, S., Rashid, T., Dintica, C. S., Gonzales, M. M., Liu, H., Ware, J. B., Austin, T. R., Jensen, P. N., Fohner, A. E., Tanley, J. E., et al. (2025) · Alzheimer s & Dementia · doi:10.1002/alz.70326 · Cited by 8 · see citing works

Tract‐Specific White Matter Hyperintensities Disrupt Brain Networks and Associated With Cognitive Impairment in Mild Traumatic Brain Injury

Li, X., Wang, Z., Zhang, H., Zhao, W., Ji, Q., Zhang, X., Jia, X., Bai, G., Pan, Y., Wu, T., et al. (2024) · Human Brain Mapping · doi:10.1002/hbm.70050 · Cited by 8 · see citing works

Frequency of Microvascular Pathology and Hippocampal Atrophy on Magnetic Resonance Imaging in a Community Study of Alzheimer's Disease with Blood‐Based Biomarkers

Gunasekaran, T. I., Sanchez, D. L., Reyes‐Dumeyer, D., Ventura, R., Morales, C. D., Alshikho, M. J., Lee, A., Lantigua, R., Gu, Y., Honig, L. S., et al. (2025) · Annals of Neurology · doi:10.1002/ana.70006 · Cited by 8 · see citing works

MarkVCID2 Consortium for Clinical Validation of Biomarkers of Cerebral Small Vessel Disease: Validation Framework and Baseline Characteristics

Greenberg, S. M., Albert, M. S., An, H., Arfanakis, K., Evia, A. M., Caprihan, A., Ford, A. L., Fornage, M., Day, G. S., Hinman, J. D., et al. (2025) · Annals of Neurology · doi:10.1002/ana.78040 · Cited by 8 · see citing works

Spatial‐temporal interactions between white matter hyperintensities and multiple pathologies across the Alzheimer's disease continuum

Liang, L., Liu, W., Zhong, Y., Guo, T., Ye, C., & Ma, T. (2025) · Alzheimer s & Dementia · doi:10.1002/alz.70098 · Cited by 7 · see citing works

Longitudinal Analysis of Neuroradiological Biomarkers for Fragile X‐Associated Tremor/Ataxia Syndrome and Implications for Clinical Trials

Hessl, D. R., Wang, J., Espinal, G. M., Santos, E. R., Tassone, F., Hagerman, R. J., & Rivera, S. M. (2025) · Annals of Neurology · doi:10.1002/ana.27267 · Cited by 7 · see citing works

High estimated pulse-wave velocity is associated with lower brain white matter microstructural integrity twelve years later

Heffernan, K. S., Monroe, D. C., London, A. S., Gutierrez, J., Brickman, A. M., Nair, A. K., Adluru, N., & Schaefer, S. M. (2025) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2025.07.015 · Cited by 7 · see citing works

Characterizing spatiotemporal white matter hyperintensity pathophysiology in vivo to disentangle vascular and neurodegenerative contributions

Parent, O., Alasmar, Z., Osborne, S., Bussy, A., Costantino, M., Fouquet, J. P., Quesada, D., Pastor‐Bernier, A., Fajardo-Valdez, A., Binette, A. P., et al. (2026) · Nature Communications · doi:10.1038/s41467-026-70832-2 · Cited by 9 · see citing works

Essential New Complexity-Based Themes for Patient-Centered Diagnosis and Treatment of Dementia and Predementia in Older People: Multimorbidity and Multilevel Phenomenology

Wertman, E. (2024) · Journal of Clinical Medicine · doi:10.3390/jcm13144202 · Cited by 6 · see citing works

Insomnia, early and late rising are associated with small hippocampal volume and large white matter hyperintensity burden

Cavaillès, C., Artéro, S., Maller, J. J., Jaussent, I., & Dauvilliers, Y. A. (2025) · Alzheimer s Research & Therapy · doi:10.1186/s13195-025-01721-x · Cited by 6 · see citing works

Impact of Small Vessel Disease on Patient Outcomes After Intravenous Thrombolysis for Acute Ischemic Stroke

Zhang, P., Luo, B., Zhang, P., Yu, X., Long, X., Du, Y., Tian, H., & Wang, L. (2024) · The American Journal of Cardiology · doi:10.1016/j.amjcard.2024.10.034 · Cited by 5 · see citing works

Cerebrovascular lesion loads and accelerated brain aging: insights into the cognitive spectrum

Beheshti, I., Potvin, O., Dadar, M., & Duchesne, S. (2024) · Frontiers in Dementia · doi:10.3389/frdem.2024.1380015 · Cited by 5 · see citing works

White matter hyperintensities in Alzheimer's disease: Beyond (but not instead of) the vascular contribution

Garnier‐Crussard, A., & Chételat, G. (2023) · Alzheimer s & Dementia · doi:10.1002/alz.13372 · Cited by 5 · see citing works

The potential of low-field MRI for global dementia care

Evans, T. E., Harper, J. R., Salehi, A., WEBB, A. G., Cole, J. H., Correa, A., Adams, H. H. H., Cash, D. M., & Jones, D. K. (2026) · Nature Reviews Neurology · doi:10.1038/s41582-026-01199-7 · Cited by 4 · see citing works

MIND diet moderates the associations between cerebrovascular and neurodegenerative disease burden and cognition

Dempsey, D. A., Unverzagt, F. W., Xu, H., Moser, L. R., Gao, S., Avena‐Koenigsberger, A., Chumin, E. J., Yoder, K. K., Agarwal, P., Tangney, C., et al. (2026) · Frontiers in Nutrition · doi:10.3389/fnut.2026.1837406 · Cited by 4 · see citing works

Management of MCI in the Outpatient Setting

Abramowitz, A., & Weber, M. (2024) · Current Psychiatry Reports · doi:10.1007/s11920-024-01514-3 · Cited by 3 · see citing works

Cerebral perfusion and gray matter volume alterations associated with cognitive impairment in metabolic syndrome with cerebral small vessel disease

Liu, H., Zheng, W., Geng, J., Zhou, X., Xia, Y., Liu, Y., Zhang, G., Zhu, X., Lv, D., & Sun, Z. (2025) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2025.1538850 · Cited by 4 · see citing works

Incremental Value of Multidomain Risk Factors for Dementia Prediction: A Machine Learning Approach

Tan, W. Y., Hargreaves, C. A., Dawe, G. S., Hsu, W., Lee, M. L., Vipin, A., Kandiah, N., & Hilal, S. (2024) · American Journal of Geriatric Psychiatry · doi:10.1016/j.jagp.2024.07.016 · Cited by 4 · see citing works

Plasma proteomics-based brain aging signature and incident dementia risk

Kou, M., Ma, H., Wang, X., Heianza, Y., & Qi, L. (2024) · GeroScience · doi:10.1007/s11357-024-01407-6 · Cited by 4 · see citing works

White matter hyperintensities and cholinergic degeneration as Lewy body disease

Kang, S. W., Jeon, S., Kim, Y. J., Jeon, S., Choi, M.-S., Lee, Y., Yun, M., & Ye, B. S. (2024) · Annals of Clinical and Translational Neurology · doi:10.1002/acn3.52257 · Cited by 4 · see citing works

Independent Role of White Matter Hyperintensity Volume and Location in Alzheimer’s Disease Risk Beyond Hippocampal Atrophy

Yang, H. J., Song, J. M., & Park, J. H. (2025) · Psychiatry Investigation · doi:10.30773/pi.2025.0127 · Cited by 3 · see citing works

Multimodal neuroimaging discrimination of Alzheimer’s disease, mild cognitive impairment, and late-life depression using electroencephalography and functional near-infrared spectroscopy: integrating electrophysiological and hemodynamic biomarkers

Mei, X., Ming, L., Ruan, N., Zhao, Z., Xu, T., & Zheng, C. (2026) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2026.1713472 · Cited by 3 · see citing works

Genetic Predisposition for White Matter Hyperintensities and Risk of Mild Cognitive Impairment and Alzheimer’s Disease: Results from the HELIAD Study

Sampatakakis, S. N., Mourtzi, N., Charisis, S., Mamalaki, E., Ntanasi, E., Hatzimanolis, A., Ramı́rez, A., Lambert, J., Yannakoulia, M., Kosmidis, M. H., et al. (2024) · Current Issues in Molecular Biology · doi:10.3390/cimb46010060 · Cited by 2 · see citing works

White matter hyperintensities and their impact in brain structure and function in alzheimer’s disease and behavioral variant frontotemporal dementia across Latin America and the United States: a cross-sectional study

Altschuler, F., Canziani, V., Fraile-Vazquez, M. E., González-Gómez, R., Hernández, H. G., Báez, S., Migeot, J., Fittipaldi, S., Maito, M. A., Legaz, A., et al. (2025) · Alzheimer s Research & Therapy · doi:10.1186/s13195-025-01832-5 · Cited by 3 · see citing works

White matter hyperintensity modulates the amyloid‐tau‐cognition association and anti‐amyloid treatment efficacy in asymptomatic older adults

Lin, Z., Hong, Y., Hu, Y., Xiao, Q., Peng, S., Wu, D., Guo, T., & Jiang, D. (2025) · Alzheimer's & Dementia · doi:10.1002/alz.70990 · Cited by 2 · see citing works

Beyond Focal Lesions: Dynamical Network Effects of White Matter Hyperintensities

Leone, R., Geysen, S., Deco, G., Kobeleva, X., & Initiative, A. D. N. (2024) · Human Brain Mapping · doi:10.1002/hbm.70081 · Cited by 2 · see citing works

Global and regional white matter hyperintensities in Alzheimer's disease: Exploring etiologies and cognitive correlates

Qiu, Y., Bao, J., Wang, T., Shang, L., Chu, S., Jin, W., Wang, W., Jiang, Y., Li, B., Huang, Y., et al. (2025) · Journal of Alzheimer s Disease · doi:10.1177/13872877251360239 · Cited by 2 · see citing works

Cognitive dispersion is associated with white matter hyperintensities in amyloid positive older adults

Ross, D., Chang, F., Edwards, L., Thomas, K. R., Bangen, K. J., & Initiative, A. D. N. (2025) · The Clinical Neuropsychologist · doi:10.1080/13854046.2025.2570301 · Cited by 2 · see citing works

PolyGR-containing aggregates link with pathology and clinical features of Alzheimer’s disease

Phuong, H. T., Tomas, R. F., Akmese, C., Mijares, A. M. P., Gerstin, I. M., Guo, S., Bell, L. R., Ellwood, R., Yegorova, S., Ng, S. K., et al. (2025) · Acta Neuropathologica · doi:10.1007/s00401-025-02954-8 · Cited by 2 · see citing works

Tooth loss is associated with subsequent brain white matter degradation up to over a decade

Tian, Q., Qi, X., Greig, E. E., Landman, B. A., Davatzikos, C. A., Resnick, S. M., Wu, B., & Ferrucci, L. (2026) · Journal of Dentistry · doi:10.1016/j.jdent.2026.106732 · Cited by 2 · see citing works

White matter hyperintensities in Alzheimer's disease in the era of anti‐amyloid therapies

Garnier‐Crussard, A., Dadar, M., Villain, N., Charidimou, A., Boulouis, G., Cotton, F., Brickman, A. M., & Chételat, G. (2026) · Alzheimer s & Dementia Diagnosis Assessment & Disease Monitoring · doi:10.1002/dad2.70349 · Cited by 2 · see citing works

Utility of cerebrovascular imaging biomarkers to detect cerebral amyloidosis

Howe, M. D., Caruso, M. R., Manoochehri, M., Kunicki, Z. J., Emrani, S., Rudolph, J. L., Huey, E. D., Salloway, S., Oh, H., & Initiative, A. D. N. (2024) · Alzheimer s & Dementia · doi:10.1002/alz.14207 · Cited by 1 · see citing works

Assessing MedSAM's Generalization to White Matter Hyperintensities in Magnetic Resonance Imaging

Rodrigues, J., do Carmo, D. S., & Rittner, L. (2024) · International Symposium on Medical Information Processing and Analysis (SIPAIM) · doi:10.1109/sipaim62974.2024.10783572 · Cited by 2 · see citing works

Onset ages of cerebrovascular disease and amyloid and effects on cognition in risk-enriched cohorts

Du, L., Planalp, E. M., Betthauser, T. J., Jonaitis, E. M., Hermann, B. P., Rivera‐Rivera, L. A., Cody, K. A., Chin, N. A., Cadman, R. V., Johnson, K. M., et al. (2025) · Brain Communications · doi:10.1093/braincomms/fcaf158 · Cited by 2 · see citing works

Distinct patterns of voxel‐ and connection‐based white matter hyperintensity distribution and associated factors in early‐onset and late‐onset Alzheimer's disease

Hong, H., Chen, Y., Liu, W., Luo, X., Zhang, M., & Initiative, A. D. N. (2024) · Alzheimer s & Dementia Diagnosis Assessment & Disease Monitoring · doi:10.1002/dad2.12585 · Cited by 1 · see citing works

Characterizing spatiotemporal white matter hyperintensity pathophysiology in vivo to disentangle vascular and neurodegenerative contributionsPreprint

Parent, O., Alasmar, Z., Osborne, S., Bussy, A., Costantino, M., Fouquet, J. P., Quesada, D., Pastor-Bernier, A., Fajardo-Valdez, A., Binette, A. P., et al. (2025) · medRxiv · doi:10.1101/2025.06.10.25329342 · Cited by 6 · see citing works

ADAMTS18 deficiency leads to abnormal brain methylation metabolism, dysregulated neuroinflammatory response, and unsound blood-brain barrier structure in mice

Liu, H., Xu, F., Zhang, M., Niu, X., Dang, S., & Zhang, W. (2025) · Metabolic Brain Disease · doi:10.1007/s11011-025-01609-7 · Cited by 1 · see citing works

Association between white matter hyperintensities and gray matter volume in cerebral small vessel disease: insights from periventricular and deep white matter lesions

Feng, W., Lei, X., Xu, S., & Xu, Z. (2025) · Frontiers in Neurology · doi:10.3389/fneur.2025.1590997 · Cited by 1 · see citing works

White matter hyperintensities contribute to early cortical thinning in addition to tau in aging

Leone, R., & Kobeleva, X. (2025) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2025.07.007 · Cited by 1 · see citing works

Gait speed and muscle mass as dual mediators in the link between white matter hyperintensities and Alzheimer's disease

Kim, J., Yang, H. J., Park, S., Kim, B. S., & Park, J. H. (2025) · Journal of Alzheimer s Disease · doi:10.1177/13872877251362424 · Cited by 1 · see citing works

Education as a domain-specific moderator: Shaping the impact of cerebral structural changes on clinical manifestations in Alzheimer's disease

Deng, T., Duan, J., Yu, W., Deng, Z., Tian, Q., Liu, X., Shou, J., Tang, T., Yu, W., & Lü, Y. (2025) · Journal of Alzheimer s Disease · doi:10.1177/13872877251379078 · Cited by 1 · see citing works

Heterogeneity of white matter hyperintensities in Alzheimer’s disease captured by multimodal neuroimaging

Garnier‐Crussard, A., Landeau, B., Mézenge, F., Gonneaud, J., Roquet, D., Cotton, F., & Chételat, G. (2025) · Scientific Reports · doi:10.1038/s41598-025-23371-7 · Cited by 1 · see citing works

Clinical correlates of perfusion and diffusion MRI metrics in cognitively unimpaired older adults

Shakibajahromi, B., Dolui, S., Brown, C., Taghvaei, M., Sadaghiani, S., Khandelwal, P., Das, S. R., Yushkevich, P. A., Nasrallah, I. M., Xie, S. X., et al. (2025) · Journal of Cerebral Blood Flow & Metabolism · doi:10.1177/0271678x251389043 · Cited by 1 · see citing works

Impact of cardiometabolic factors and AD plasma biomarkers on white matter hyperintensities volume in individuals with cognitive complaints from the global south

Riquelme-Contreras, P., Henríquez, F., Gonzalez-Campo, C., Altschuler, F., Fraile-Vazquez, M., Ferreira, P. C. L., Bellaver, B., Karikari, T. K., Pascoal, T. A., Okuma, C., et al. (2025) · Neuroscience · doi:10.1016/j.neuroscience.2025.11.013 · Cited by 1 · see citing works

Polygenic risk for white matter hyperintensities is associated with early cerebrovascular events partly through hemodynamic measures in cognitively unimpaired middle-aged and older adults with low cardiovascular risk

Genius, P., Rodríguez‐Fernández, B., Minguillón, C., Brugulat‐Serrat, A., Huguet, J., Esteller, M., Sudre, C. H., Cortés‐Canteli, M., Tristão‐Pereira, C., García‐Lunar, I., et al. (2026) · Frontiers in Neurology · doi:10.3389/fneur.2025.1667424 · Cited by 1 · see citing works

The Relationship Between Hippocampal Cerebrovascular Reactivity and Brain Structure in Older Age

Wang, C., Jobbins, L., Reid, G., Hobden, G., Patel, R., Mackay, C. E., Ebmeier, K. P., Pinto, J., Bulte, D. P., Mika Kivimaki, B., et al. (2026) · Human Brain Mapping · doi:10.1002/hbm.70445 · Cited by 1 · see citing works

Early-onset axonal pathology and β-amyloidosis in human brains with hematological malignances and cardiovascular diseases

Wang, Y., Sun, Z., Zhou, P., Tu, T., Zhang, X.-J., Tu, E., Chen, H., Cheng, H.-Y., Pan, A., Zhang, Q., et al. (2026) · Neuroscience · doi:10.1016/j.neuroscience.2026.03.032 · Cited by 1 · see citing works

MRI evaluation of cerebral perivascular spaces predicts amyloid-related imaging abnormalities risk in preclinical Alzheimer's disease

Bigjahan, B., Cavallari, M., & Barisano, G. (2026) · Frontiers in Dementia · doi:10.3389/frdem.2026.1719740 · Cited by 3 · see citing works

Desynchronise, disconnect, reorganise, collapse (DDRC): A theoretical framework linking white matter pathology and cognitive dysfunction in vascular disease

Moran, K. L., Smith, C. J., Montaldi, D., & Muhlert, N. (2026) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2026.106687 · Cited by 1 · see citing works

Operationalizing diffusion magnetic resonance imaging positivity for detection of vascular contributions to impairment and dementia

Hu, M., Przybelski, S. A., Therneau, T. M., Lundt, E. S., Wiste, H. J., Mester, C. T., Kamykowski, M. G., Reid, R. I., Machulda, M. M., Knopman, D. S., et al. (2026) · Alzheimer s & Dementia · doi:10.1002/alz.71438 · Cited by 1 · see citing works

Cerebral amyloid-β burden and white matter injury: associations, clues for underlying mechanisms, and implication on cognitive trajectory after lecanemab therapy

Shi, K., Luo, X., Liu, T., Liu, W.-Z., Dong, Y.-F., Zheng, F.-B., Zhou, X., Xing, J.-S., Sun, Z.-H., Chen, Q.-Q., et al. (2026) · Journal of Advanced Research · doi:10.1016/j.jare.2026.08.057 · Cited by 1 · see citing works

Lesion-Level Subtypes of White Matter Hyperintensity Evolution Beyond Spatial Location

González-Gómez, R., Tagliazuchi, E., Gonzalez-Campo, C., Medel, V., Bennett, D. A., & Iturria‐Medina, Y. (2026) · Neurology · doi:10.1212/wnl.0000000000218472 · Cited by 1 · see citing works

Induction of ferroptotic and amyloidogenic signatures linked to Alzheimer's disease by chemically distinct air pollutants

Shkirkova, K., Maria, N. S. S., Anson, H., Aghaei, Y., Badami, M. M., Chakhoyan, A., Godoy-Lugo, J. A., Chung, C. S., Durra, S., Tang-Tan, A. M., et al. (2026) · Redox Biology · doi:10.1016/j.redox.2026.104390 · Cited by 1 · see citing works

A matter of fragmentation

THOMAS, R. J. (2024) · SLEEP · doi:10.1093/sleep/zsae030 · Cited by 1 · see citing works

Study on Serological Markers and Brain Structural Changes in Early Clinical Stage of Alzheimer's Disease in Cold Regions

Yin, C., Chen, L., Wang, J., & Zhao, W. (2025) · Actas Españolas de Psiquiatría · doi:10.62641/aep.v53i4.1936 · Cited by 1 · see citing works

Gut Microbiota and White Matter Integrity: A Two-Sample Mendelian Randomization Analysis

Zhang, L., Pang, X., Zhang, L., Zhu, L., Li, W.-N., Chu, Y., Zhou, L., Tian, D., Qin, C., & Chen, L. (2025) · eNeuro · doi:10.1523/eneuro.0586-24.2025 · Cited by 1 · see citing works

Longitudinal evidence for a mutually reinforcing relationship between white matter hyperintensities and cortical thickness in cognitively unimpaired older adultsPreprint

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Lipid-regulatory mechanisms drive cerebrovascular disease in asymptomatic individuals at low risk for late-life dementiaPreprint

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