The DOI matches its Crossref record; 73 of the 73 references it cites were found in a registry or an index.
Deficient glutamate tranport is associated with neurodegeneration in Alzheimer's disease
Abstract
The mechanisms of synapse damage in Alzheimer's disease (AD) are not fully understood. Deficient functioning of glutamate transporters might be involved in synaptic pathology and neurodegeneration by failing to clear excess glutamate at the synaptic cleft. In AD, glutamate transporter activity as assessed by D-[3H]aspartate binding is decreased; however, it is not clear to what extent it is associated with the neurodegenerative process and cognitive alterations. For this purpose, levels of D- and L-[3H]aspartate binding in midfrontal cortex were correlated with synaptophysin levels, brain spectrin degradation product levels, and clinical and neuropathological indicators of AD. Compared to control brains, AD brains displayed a 34% decrease in levels of D-[3H]aspartate binding, a 30% decrease in L-[3H]aspartate binding, and a 48% loss of synaptophysin immunoreactivity. Increased levels of brain spectrin degradation products correlated with a decrease in levels of D-[3H] and L-[3H]aspartate binding, and decreased levels of synaptophysin immunoreactivity. Levels of L-[3H]aspartate binding correlated with levels of synaptophysin immunoreactivity. These results suggest that decreased glutamate transporter activity in AD is associated with increased excitotoxicity and neurodegeneration, supporting the possibility that abnormal functioning of this system might be involved in the pathogenesis of synaptic damage in AD.
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In the citing paper
“Glutamine is produced from glutamate by the activity of glutamine synthetase (GS) [124,131].”
From Mitochondrial Oxidative and Nitrosative Stress and Alzheimer Disease (2020) · cites this paper as [131]
In the citing paper
“but its activity is decreased in AD brain, which is likely due to oxidative modification by HNE [26,131].”
From Mitochondrial Oxidative and Nitrosative Stress and Alzheimer Disease (2020) · cites this paper as [131]
In the citing paper
“The glial glutamate transporter (GLT-1), also known as the excitatory amino acid transporter-2 (EAAT2), is responsible for the uptake of synaptic glutamate”
From Mitochondrial Oxidative and Nitrosative Stress and Alzheimer Disease (2020) · cites this paper as [131]
In the citing paper
“Loss or dysfunction of SLC1A2 has been implicated in multiple neurodegenerative and neuropsychiatric disorders, including AD where it is closely associated with cognitive decline [126–131].”
From Tau Ablation Rewires Brain Cell Programs in Health and Restores Function in Disease (2026) · cites this paper as [129]
In the citing paper
“EAAT2 expression diminishes with age60 and correlates with signs of neuronal death in postmortem brains of sporadic AD patients61.”
From The R136S mutation in the APOE3 gene confers resilience against tau pathology via inhibition of the cGAS-STING-IFN pathway (2025) · cites this paper as [61]
In the citing paper
“in postmortem brains of patients with sporadic AD correlates with signs of neuronal death56”
From APOE3 - R136S mutation confers resilience against tau pathology via cGAS-STING-IFN inhibition (2024) · cites this paper as [56]
Citations
Cites
PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT
Lowry, O. H., Rosebrough, N., Farr, A. L., & Randall, R. (1951) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)52451-6 · Cited by 316,394
Neuropathological stageing of Alzheimer-related changes.
Braak, H., & Braak, E. (1991) · Acta Neuropathologica · doi:10.1007/bf00308809 · Cited by 16,123
LIGAND: A versatile computerized approach for characterization of ligand-binding systems
Munson, P. J., & Rodbard, D. (1980) · Analytical Biochemistry · doi:10.1016/0003-2697(80)90515-1 · Cited by 8,373
Goate, A., Chartier-Harlin, M.-C., Mullan, M., Brown, J., Crawford, F., Fidani, L., Giuffra, L., Haynes, A., Irving, N., James, L., et al. (1991) · Nature · doi:10.1038/349704a0 · Cited by 4,659
Terry, R. D., Masliah, E., Salmon, D. P., Butters, N., DeTeresa, R., Hill, R., Hansen, L. A., & Katzman, R. (1991) · Annals of Neurology · doi:10.1002/ana.410300410 · Cited by 4,397
Neurofibrillary tangles but not senile plaques parallel duration and severity of Alzheimer's disease
Arriagada, P. V., Growdon, J. H., Hedley-Whyte, E. T., & Hyman, B. T. (1992) · Neurology · doi:10.1212/wnl.42.3.631 · Cited by 2,668
Alzheimer-type neuropathology in transgenic mice overexpressing V717F β-amyloid precursor protein
Games, D., Adams, D., Alessandrini, R., Barbour, R., Borthelette, P., Blackwell, C., Carr, T., Clemens, J., Donaldson, T., Gillespie, F., et al. (1995) · Nature · doi:10.1038/373523a0 · Cited by 2,516
Self-citationSynapse loss in frontal cortex biopsies in Alzheimer's disease: Correlation with cognitive severity
DeKosky, S. T., & Scheff, S. W. (1990) · Annals of Neurology · doi:10.1002/ana.410270502 · Cited by 2,376
Ionic dependence of glutamate neurotoxicity
Choi, D. W. (1987) · Journal of Neuroscience · doi:10.1523/jneurosci.07-02-00369.1987 · Cited by 1,854
Localization of neuronal and glial glutamate transporters
Rothstein, J. D., Martin, L. J., Levey, A. I., Dykes‐Hoberg, M., Jin, L., Wu, D. M., Nash, N. R., & Kuncl, R. W. (1994) · Neuron · doi:10.1016/0896-6273(94)90038-8 · Cited by 1,703
Selective loss of glial glutamate transporter GLT‐1 in amyotrophic lateral sclerosis
Rothstein, J. D., Van Kammen, M., Levey, A. I., Martin, L. J., & Kuncl, R. W. (1995) · Annals of Neurology · doi:10.1002/ana.410380114 · Cited by 1,471
Wiedenmann, B. J., & Franke, W. W. (1985) · Cell · doi:10.1016/s0092-8674(85)80082-9 · Cited by 1,432
Primary structure and functional characterization of a high-affinity glutamate transporter
Kanai, Y., & Hediger, M. A. (1992) · Nature · doi:10.1038/360467a0 · Cited by 1,337
Cloning and expression of a rat brain L-glutamate transporter
Pines, G., Danbolt, N. C., Bjørås, M., Zhang, Y., Bendahan, A., Eide, L., Koepsell, H., Storm‐Mathisen, J., Seeberg, E. C., & Kanner, B. I. (1992) · Nature · doi:10.1038/360464a0 · Cited by 1,242
Chartier-Harlin, M.-C., Crawford, F., Houlden, H., Warren, A., Hughes, D., Fidani, L., Goate, A., Rossor, M., Roques, P., Hardy, J., et al. (1991) · Nature · doi:10.1038/353844a0 · Cited by 1,214
Storck, T., Schulte, S., Hofmann, K., & Stoffel, W. (1992) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.89.22.10955 · Cited by 1,193
A mutation in the Amyloid Precursor Protein Associated with Hereditary Alzheimer's Disease
Murrell, J. R., Farlow, M. R., Ghetti, B. F., & Benson, M. D. (1991) · Science · doi:10.1126/science.1925564 · Cited by 1,142
Masters, C. L., Multhaup, G., Simms, G., Pottgiesser, J., Martins, R. N., & Beyreuther, K. T. (1985) · The EMBO Journal · doi:10.1002/j.1460-2075.1985.tb04000.x · Cited by 1,048
The TINS/TiPS Lecture the molecular biology of mammalian glutamate receptor channels
Seeburg, P. H. (1993) · Trends in Neurosciences · doi:10.1016/0166-2236(93)90093-2 · Cited by 884
A 38,000-dalton membrane protein (p38) present in synaptic vesicles.
Jahn, R., SCHIEBLER, W., Ouimet, C. C., & Greengard, P. (1985) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.82.12.4137 · Cited by 851
A practical computer-based approach to the analysis of radioligand binding experiments
McPherson, G. A. (1983) · Computer Programs in Biomedicine · doi:10.1016/0010-468x(83)90031-4 · Cited by 823
Some morphometric aspects of the brain in senile dementia of the alzheimer type
Terry, R. D., Peck, A., DeTeresa, R., Schechter, R., & Horoupian, D. S. (1981) · Annals of Neurology · doi:10.1002/ana.410100209 · Cited by 801
Neurotransmitter enzyme abnormalities in senile dementia
Perry, E. K., Gibson, P. H., Blessed, G., Perry, R. H., & Tomlinson, B. E. (1977) · Journal of the Neurological Sciences · doi:10.1016/0022-510x(77)90073-9 · Cited by 724
Perforant pathway changes and the memory impairment of Alzheimer's disease
Hyman, B. T., Van Hoesen, G. W., Kromer, L. J., & Damasio, A. R. (1986) · Annals of Neurology · doi:10.1002/ana.410200406 · Cited by 672
Mattson, M. P., Cheng, B., Culwell, A. R., Esch, F. S., Lieberburg, I., & Rydel, R. E. (1993) · Neuron · doi:10.1016/0896-6273(93)90315-i · Cited by 656
ULTRASTRUCTURAL STUDIES IN ALZHEIMER'S PRESENILE DEMENTIA.
Terry, R. D., Gonatas, N. K., & WEISS, M. (1964) · PubMed Central · Cited by 644
Davies, C. A., Mann, D. M. A., Sumpter, P. Q., & Yates, P. O. (1987) · Journal of the Neurological Sciences · doi:10.1016/0022-510x(87)90057-8 · Cited by 628
Mattson, M. P., Tomaselli, K. J., & Rydel, R. E. (1993) · Brain Research · doi:10.1016/0006-8993(93)90295-x · Cited by 380
Synaptic and neuritic alterations during the progression of Alzheimer's disease
Masliah, E., Mallory, M., Hansen, L., Richard, D., Alford, M., & Terry, R. (1994) · Neuroscience Letters · doi:10.1016/0304-3940(94)90121-x · Cited by 370
Self-citationSecreted Forms of β‐Amyloid Precursor Protein Protect Against Ischemic Brain Injury
Smith‐Swintosky, V. L., Pettigrew, L. C., Craddock, S. D., Culwell, A. R., Rydel, R. E., & Mattson, M. P. (1994) · Journal of Neurochemistry · doi:10.1046/j.1471-4159.1994.63020781.x · Cited by 284
Localization of Alzheimer βA4 amyloid precursor protein at central and peripheral synaptic sites
SCHUBERT, W. J., Prior, R., Weidemann, A., Dircksen, H., Multhaup, G., Masters, C. L., & Beyreuther, K. T. (1991) · Brain Research · doi:10.1016/0006-8993(91)91532-6 · Cited by 272
Synaptotrophic effects of human amyloid β protein precursors in the cortex of transgenic mice
Mucke, L., Masliah, E., Johnson, W. B., Ruppe, M. D., Alford, M. F., Rockenstein, E. M., Forss‐Petter, S., Pietropaolo, M., Mallory, M. E., & Abraham, C. R. (1994) · Brain Research · doi:10.1016/0006-8993(94)90767-6 · Cited by 270
Roch, J., Masliah, E., Roch‐Levecq, A., Sundsmo, M. P., Otero, D. A., Veinbergs, I., & Saitoh, T. (1994) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.91.16.7450 · Cited by 255
Patterns of aberrant sprouting in alzheimer's disease
Masliah, E., Mallory, M. E., Hansen, L. A., Alford, M. F., Albright, T., DeTeresa, R. M., Terry, R. D., Baudier, J., & Saitoh, T. (1991) · Neuron · doi:10.1016/0896-6273(91)90170-5 · Cited by 243
Research advances in Alzheimer's disease and related disorders
Iqbal, K., & Disorders, R. (1995) · Wiley eBooks · Cited by 228
Lowy, M. T., Wittenberg, L., & Yamamoto, B. K. (1995) · Journal of Neurochemistry · doi:10.1046/j.1471-4159.1995.65010268.x · Cited by 217
Masliah, E., Fagan, A. M., Terry, R. D., DeTeresa, R. M., Mallory, M. E., & Gage, F. H. (1991) · Experimental Neurology · doi:10.1016/0014-4886(91)90169-d · Cited by 204
The elusive transporters with a high affinity for glutamate
Kanai, Y., Smith, C. P., & Hediger, M. A. (1993) · Trends in Neurosciences · doi:10.1016/0166-2236(93)90094-3 · Cited by 198
Heinonen, O., Soininen, H., Sorvari, H., Kosunen, O., Paljärvi, L., Koivisto, E., & Riekkinen, P. J. (1995) · Neuroscience · doi:10.1016/0306-4522(94)00422-2 · Cited by 188
Electrogenic Properties of the Epithelial and Neuronal High Affinity Glutamate Transporter
Kanai, Y., Nußberger, S., Romero, M. F., Boron, W. F., Hébert, S., & Hediger, M. A. (1995) · Journal of Biological Chemistry · doi:10.1074/jbc.270.28.16561 · Cited by 184
Masliah, E., Ellisman, M., Carragher, B., Mallory, M., Young, S., Hansen, L., Deteresa, R., & Terry, R. D. (1992) · Journal of Neuropathology and Experimental Neurology · doi:10.1097/00005072-199207000-00003 · Cited by 183
(1995) · PubMed · Cited by 167
Arai, H., Lee, V. M. ‐., Messinger, M. L., Greenberg, B., Lowery, D. E., & Trojanowski, J. Q. (1991) · Annals of Neurology · doi:10.1002/ana.410300509 · Cited by 165
Lassmann, H., Weiler, R., Fischer, P. A., Bancher, C., Jellinger, K. A., Floor, E., Danielczyk, W., SEITELBERGER, F., & Winkler, H. J. S. (1992) · Neuroscience · doi:10.1016/0306-4522(92)90003-k · Cited by 161
Card, J. P., Meade, R. P., & Davis, L. G. (1988) · Neuron · doi:10.1016/0896-6273(88)90131-6 · Cited by 155
Amyloid β protein precursor and the pathogenesis of Alzheimer's disease
Selkoe, D. J. (1989) · Cell · doi:10.1016/0092-8674(89)90093-7 · Cited by 154
The Role of Synaptic Proteins in the Pathogenesis of Disorders of the Central Nervous System
Masliah, E., & Terry, R. D. (1993) · Brain Pathology · doi:10.1111/j.1750-3639.1993.tb00728.x · Cited by 145
Brain spectrin, calpain and long-term changes in synaptic efficacy
LYNCH, G. S., & Baudry, M. (1987) · Brain Research Bulletin · doi:10.1016/0361-9230(87)90220-6 · Cited by 144
Spectrin subtypes in mammalian brain: an immunoelectron microscopic study
Zagon, I., Higbee, R. G., Riederer, B. M., & Goodman, S. R. (1986) · Journal of Neuroscience · doi:10.1523/jneurosci.06-10-02977.1986 · Cited by 136
Gundersen, V., Danbolt, N. C., Ottersen, O. P., & Storm‐Mathisen, J. (1993) · Neuroscience · doi:10.1016/0306-4522(93)90114-u · Cited by 135
Kanai, Y., Stelzner, M. G., Nußberger, S., Khawaja, S., Hébert, S., Smith, C. P., & Hediger, M. A. (1994) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(17)32035-5 · Cited by 132
Mattson, M. P., Cheng, B., & Smith‐Swintosky, V. L. (1993) · Experimental Neurology · doi:10.1006/exnr.1993.1178 · Cited by 121
Masliah, E., Mallory, M. E., Hansen, L. A., Alford, M. F., DeTeresa, R. M., & Terry, R. D. (1993) · PubMed · Cited by 107
Molecular Genetics of Alzheimer's Disease
Clark, R. F., & Goate, A. (1993) · Archives of Neurology · doi:10.1001/archneur.1993.00540110044004 · Cited by 100
Presynaptic and postsynaptic glutamatergic function in Alzheimer's disease
Cowburn, R. F., Hardy, J., Roberts, P., & BRIGGS, R. S. J. (1988) · Neuroscience Letters · doi:10.1016/0304-3940(88)90192-9 · Cited by 98
Masliah, E., Mallory, M. E., Hansen, L. A., Alford, M. F., DeTeresa, R. M., Terry, R. D., Baudier, J., & Saitoh, T. (1992) · Brain Research · doi:10.1016/0006-8993(92)90831-s · Cited by 91
Delayed Antagonism of Calpain Reduces Excitotoxicity in Cultured Neurons
Brorson, J. R., Marcuccilli, C. J., & Miller, R. J. (1995) · Stroke · doi:10.1161/01.str.26.7.1259 · Cited by 89
Mucke, L., Abraham, C. R., Ruppe, M. D., Rockenstein, E. M., Toggas, S. M., Mallory, M. E., Alford, M. F., & Masliah, E. (1995) · The Journal of Experimental Medicine · doi:10.1084/jem.181.4.1551 · Cited by 88
Seubert, P. A., Ivy, G. O., Larson, J., Lee, J., Shahi, K., Baudry, M., & LYNCH, G. S. (1988) · Brain Research · doi:10.1016/0006-8993(88)90638-5 · Cited by 78
Variant Forms of Neuronal Glutamate Transporter Sites in Alzheimer's Disease Cerebral Cortex
Scott, H. L., Tannenberg, A. E. G., & Dodd, P. R. (1995) · Journal of Neurochemistry · doi:10.1046/j.1471-4159.1995.64052193.x · Cited by 74
Regional changes in [3H]d-aspartate and [3H]TCP binding sites in Alzheimer's disease brains
Simpson, M. D. C., Royston, M. C., Deakin, J. F. W., Cross, A. J., Mann, D. M. A., & Slater, P. (1988) · Brain Research · doi:10.1016/0006-8993(88)90587-2 · Cited by 74
Balcar, V. J., & Li, Y. (1992) · Life Sciences · doi:10.1016/0024-3205(92)90556-5 · Cited by 63
Alford, M. F., Masliah, E., Hansen, L. A., & Terry, R. D. (1994) · Journal of Histochemistry & Cytochemistry · doi:10.1177/42.2.8288869 · Cited by 63
Increased immunoreactivity of brain spectrin in Alzheimer disease: a marker for synapse loss?
Masliah, E., Iimoto, D. S., Saitoh, T., Hansen, L. A., & Terry, R. D. (1990) · Brain Research · doi:10.1016/0006-8993(90)90755-z · Cited by 61
Askanas, V., Engel, W. K., & Alvarez, R. B. (1992) · Neuroscience Letters · doi:10.1016/0304-3940(92)90241-x · Cited by 55
Bowes, M. P., Masliah, E., Otero, D. A. C., Zivin, J. A., & Saitoh, T. (1994) · Experimental Neurology · doi:10.1006/exnr.1994.1152 · Cited by 54
The association of [3H]d-aspartate binding and high-affinity glutamate uptake in the human brain
Cross, A. J., Skan, W., & Slater, P. (1986) · Neuroscience Letters · doi:10.1016/0304-3940(86)90047-9 · Cited by 43
Glutamatergic neurotransmission in Alzheimer's disease
Cowburn, R. F., Hardy, J., & Roberts, P. J. J. (1990) · Biochemical Society Transactions · doi:10.1042/bst0180390 · Cited by 27
Glutamate/Aspartate-Releasing Neurons in Alzheimer's Disease
PROCTER, A. W., Palmer, A. M., Stratmann, G. C., & Bowen, D. M. (1986) · New England Journal of Medicine · doi:10.1056/nejm198606263142617 · Cited by 24
Identification of Amyloid Precursor Protein in Synaptic Plasma Membrane
Shimokawa, M., Yanagisawa, K., Nishiye, H., & Miyatake, T. (1993) · Biochemical and Biophysical Research Communications · doi:10.1006/bbrc.1993.2240 · Cited by 17
The American Society for Neural Transplantation
Sladek, J. R. (1994) · Experimental Neurology · doi:10.1006/exnr.1994.1141 · Cited by 15
Autoradiography of L-[3H]aspartate binding sites
Anderson, K. J., & Sandler, D. L. (1993) · Life Sciences · doi:10.1016/0024-3205(93)90515-5 · Cited by 11
The Biological Function of Amyloid β/A4 Protein Precursor
Saitoh, T., Roch, J., Jin, L.-W., Ninomiya, H., Otero, D. A. C., Yamamoto, K., & Masliah, E. (1994) · Springer eBooks · doi:10.1007/978-3-662-01135-5_9 · Cited by 6
Research works printed but not linked: 6
- Masliah E, 1994, The role of synaptic pathology in the mechanisms of dementia in Alzheimer's disease, Clin Neurosci, 1, 192
- Hof PR, 1994, Alzheimer disease, 197
- Palmer AM, 1990, Is the neuronal basis of Alzheimer's disease cholinergic or glutamaterigc?, FASEB J, 2745, 2752
- Masliah E, 1995, Abnormal synaptic regeneration in hAPP695 transgenic and APOE knockout mice, 405
- Greenamyre JT, 1994, Anatomy and physiology of lgutamate in the CNS, Neurology, 44, S7
- 10.1002/ana.410380114 · DOI · Paper page
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Wang, R., & Reddy, P. H. (2017) · Journal of Alzheimer’s Disease · doi:10.3233/jad-160763 · Cited by 1,009
Li, S., Hong, S., Shepardson, N. E., Walsh, D. M., Shankar, G. M., & Selkoe, D. (2009) · Neuron · doi:10.1016/j.neuron.2009.05.012 · Cited by 972
Allan Butterfield, D. (2002) · Free Radical Research · doi:10.1080/1071576021000049890 · Cited by 786
Allanbutterfield, D., Castegna, A., Lauderback, C. M., & Drake, J. (2002) · Neurobiology of Aging · doi:10.1016/s0197-4580(01)00340-2 · Cited by 715
Metadata
- Authors
- Masliah, E., Hansen, L., Alford, M., Deteresa, R., & Mallory, M.
- Affiliations
- University of California San Diego (US)
- Corresponding author
- Masliah, E.
- Venue
- Annals of Neurology
- Publisher
- Wiley
- Published
- 1996-11
- Volume
- 40
- Issue
- 5
- Pages
- 759-766
- ISSN
- 0364-5134 (ISSN-L)
- 1531-8249
- OpenAlex
- W2050523782
- Cited by
- 476
- References
- 73
- Citations by year
- 2026: 13 · 2025: 17 · 2024: 20 · 2023: 17 · 2022: 27 · 2021: 21 · 2020: 24 · 2019: 32 · 2018: 24 · 2017: 17 · 2016: 11 · 2015: 20 · 2014: 13 · 2013: 10 · 2012: 12
- FWCI
- 6.74
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Annals of Neurology (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Institute on Aging (AG10689, AG05131, R01AG010689, P50AG005131)
- Topics
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Alzheimer's disease research and treatments
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neuroscience and Neuropharmacology Research
- Health Sciences › Medicine › Psychiatry and Mental health › Dementia and Cognitive Impairment Research
- Keywords
- Alzheimer's disease, glutamate transporters, excitotoxicity, neurodegeneration, synapse damage, synaptophysin, synaptic pathology
- MeSH terms
- Aged, Aspartic Acid, Autopsy, Biological Transport, Brain, Frontal Lobe, Humans, Nerve Degeneration, Organ Specificity, Reference Values, Regression Analysis, Spectrin, Biomarkers, Synaptophysin, Neurofibrillary Tangles, ATP-Binding Cassette Transporters, Amino Acid Transport System X-AG
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