From Designing the Molecules of Life to Designing Life: Future Applications Derived from Advances in DNA Technologies.

Folding DNA to create nanoscale shapes and patterns

Rothemund, P. W. K. (2006) · Nature · doi:10.1038/nature04586 · Cited by 7,320 · see citing works

Spatially resolved, highly multiplexed RNA profiling in single cells

Chen, K. H., Boettiger, A. N., Moffitt, J. R., Wang, S., & Zhuang, X. (2015) · Science · doi:10.1126/science.aaa6090 · Cited by 2,969 · see citing works

Creation of a Bacterial Cell Controlled by a Chemically Synthesized Genome

Gibson, D. G., Glass, J. I., Lartigue, C., Noskov, V. N., Chuang, R.-Y., Algire, M. A., Benders, G. A., Montague, M. G., Ma, L., Moodie, M. M., et al. (2010) · Science · doi:10.1126/science.1190719 · Cited by 2,638 · see citing works

Self-assembly of DNA into nanoscale three-dimensional shapes

Douglas, S. M., Dietz, H., Liedl, T., Högberg, B., Graf, F., & Shih, W. M. (2009) · Nature · doi:10.1038/nature08016 · Cited by 2,579 · see citing works

Nucleic acid junctions and lattices

Seeman, N. C. (1982) · Journal of Theoretical Biology · doi:10.1016/0022-5193(82)90002-9 · Cited by 2,505 · see citing works

Evolution by gene duplication: An update

Zhang, J. (2003) · Trends in Ecology & Evolution · doi:10.1016/s0169-5347(03)00033-8 · Cited by 2,201 · see citing works

A Logic-Gated Nanorobot for Targeted Transport of Molecular Payloads

Douglas, S. M., Bachelet, I., & Church, G. M. (2012) · Science · doi:10.1126/science.1214081 · Cited by 2,187 · see citing works

Triggered amplification by hybridization chain reaction

Dirks, R. M., & Pierce, N. A. (2004) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0407024101 · Cited by 2,077 · see citing works

In Vivo Half-Life of a Protein Is a Function of Its Amino-Terminal Residue

Bachmair, A., Finley, D. J., & Varshavsky, A. J. (1986) · Science · doi:10.1126/science.3018930 · Cited by 1,976 · see citing works

Ultraconserved Elements in the Human Genome

Bejerano, G., Pheasant, M., Makunin, I., Stephen, S., Kent, W. J., Mattick, J. S., & Haussler, D. (2004) · Science · doi:10.1126/science.1098119 · Cited by 1,732 · see citing works

Self-assembly of a nanoscale DNA box with a controllable lid

Andersen, E. S., Dong, M., Nielsen, M. M., Jahn, K., Subramani, R., Mamdouh, W., Golas, M. M., Sander, B. O., Stark, H., Oliveira, C. L. P., et al. (2009) · Nature · doi:10.1038/nature07971 · Cited by 1,628 · see citing works

Expansion microscopy

Chen, F., Tillberg, P. W., & Boyden, E. S. (2015) · Science · doi:10.1126/science.1260088 · Cited by 1,531 · see citing works

Programming cells by multiplex genome engineering and accelerated evolution

Wang, H. H., Isaacs, F. J., Carr, P. A., Sun, Z. Z., Xu, G., Forest, C. R., & Church, G. M. (2009) · Nature · doi:10.1038/nature08187 · Cited by 1,529 · see citing works

Expanding the Genetic Code of Escherichia coli

Wang, L., Brock, A., Herberich, B., & Schultz, P. G. (2001) · Science · doi:10.1126/science.1060077 · Cited by 1,504 · see citing works

Design and synthesis of a minimal bacterial genome

Hutchison, C. A., Chuang, R.-Y., Noskov, V. N., Assad-Garcia, N., Deerinck, T. J., Ellisman, M. H., Gill, J., Kannan, K., Karas, B. J., Ma, L., et al. (2016) · Science · doi:10.1126/science.aad6253 · Cited by 1,500 · see citing works

Next-Generation Digital Information Storage in DNA

Church, G. M., Gao, Y., & Kosuri, S. (2012) · Science · doi:10.1126/science.1226355 · Cited by 1,441 · see citing works

Accurate Multiplex Polony Sequencing of an Evolved Bacterial Genome

Shendure, J., Porreca, G. J., Reppas, N. B., Lin, X., McCutcheon, J. P., Rosenbaum, A. M., Wang, M. D., Zhang, K., Mitra, R. D., & Church, G. M. (2005) · Science · doi:10.1126/science.1117389 · Cited by 1,402 · see citing works

Folding DNA into Twisted and Curved Nanoscale Shapes

Dietz, H., Douglas, S. M., & Shih, W. M. (2009) · Science · doi:10.1126/science.1174251 · Cited by 1,340 · see citing works

Three-Dimensional Structures Self-Assembled from DNA Bricks

Ke, Y., Ong, L. L., Shih, W. M., & Yin, P. (2012) · Science · doi:10.1126/science.1227268 · Cited by 1,249 · see citing works

Complete Chemical Synthesis, Assembly, and Cloning of a <i>Mycoplasma genitalium</i> Genome

Gibson, D. G., Benders, G. A., Andrews-Pfannkoch, C., Denisova, E. A., Baden-Tillson, H., Zaveri, J., Stockwell, T. B., Brownley, A., Thomas, D. W., Algire, M. A., et al. (2008) · Science · doi:10.1126/science.1151721 · Cited by 1,243 · see citing works

Rapid prototyping of 3D DNA-origami shapes with caDNAno

Douglas, S. M., Marblestone, A. H., Teerapittayanon, S., Vazquez, A., Church, G. M., & Shih, W. M. (2009) · Nucleic Acids Research · doi:10.1093/nar/gkp436 · Cited by 1,226 · see citing works

Towards Practical, High-Capacity, Low-Maintenance Information Storage in Synthesized DNA

Goldman, N., Bertone, P., Chen, S., Dessimoz, C., LeProust, E. M., Sipos, B., & Birney, E. (2013) · Nature · doi:10.1038/nature11875 · Cited by 1,220 · see citing works

DNA Origami with Complex Curvatures in Three-Dimensional Space

Han, D., Pal, S., Nangreave, J., Deng, Z., Liu, Y., & Yan, H. (2011) · Science · doi:10.1126/science.1202998 · Cited by 1,216 · see citing works

Multiplexed 3D cellular super-resolution imaging with DNA-PAINT and Exchange-PAINT

Jungmann, R., Avendaño, M. S., Woehrstein, J. B., Dai, M., Shih, W. M., & Yin, P. (2014) · Nature Methods · doi:10.1038/nmeth.2835 · Cited by 1,137 · see citing works

DNA Origami: Scaffolds for Creating Higher Order Structures

Fan, H. B., Zhang, F., Liu, Y., & Yan, H. (2017) · Chemical Reviews · doi:10.1021/acs.chemrev.6b00825 · Cited by 1,090 · see citing works

Initial impact of the sequencing of the human genome

Lander, E. S. (2011) · Nature · doi:10.1038/nature09792 · Cited by 1,044 · see citing works

Modern methods for delivery of drugs across the blood–brain barrier

Chen, Y., & Liu, L. (2011) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2011.11.010 · Cited by 1,005 · see citing works

Nanomaterials based on DNA

Seeman, N. C. (2010) · Annual Review of Biochemistry · doi:10.1146/annurev-biochem-060308-102244 · Cited by 992 · see citing works

Single-cell in situ RNA profiling by sequential hybridization

Lubeck, E., Coskun, A. F., Zhiyentayev, T., Ahmad, M., & Cai, L. (2014) · Nature Methods · doi:10.1038/nmeth.2892 · Cited by 985 · see citing works

Highly Multiplexed Subcellular RNA Sequencing in Situ

Lee, J. H., Daugharthy, E. R., Scheiman, J., Kalhor, R., Yang, J. L., Ferrante, T. C., Terry, R., Jeanty, S. S. F., Li, C., Amamoto, R., et al. (2014) · Science · doi:10.1126/science.1250212 · Cited by 973 · see citing works

In situ sequencing for RNA analysis in preserved tissue and cells

Ke, R., Mignardi, M., Pacureanu, A., Svedlund, J., Botling, J., Wählby, C., & Nilsson, M. (2013) · Nature Methods · doi:10.1038/nmeth.2563 · Cited by 934 · see citing works

A primer to scaffolded DNA origami

Castro, C. E., Kilchherr, F., Kim, D., Lin-Shiao, E., Wauer, T., Wortmann, P., Bathe, M., & Dietz, H. (2011) · Nature Methods · doi:10.1038/nmeth.1570 · Cited by 926 · see citing works

DNA Fountain enables a robust and efficient storage architecture

Erlich, Y., & Zielinski, D. (2017) · Science · doi:10.1126/science.aaj2038 · Cited by 898 · see citing works

Genomically Recoded Organisms Expand Biological Functions

Lajoie, M. J., Rovner, A. J., Goodman, D. B., Aerni, H. R., Haimovich, A. D., Kuznetsov, G., Mercer, J. A. M., Wang, H. H., Carr, P. A., Mosberg, J. A., et al. (2013) · Science · doi:10.1126/science.1241459 · Cited by 859 · see citing works

Robust Chemical Preservation of Digital Information on DNA in Silica with Error-Correcting Codes

Grass, R. N., Heckel, R., Puddu, M., Paunescu, D., & Stark, W. J. (2015) · Angewandte Chemie International Edition · doi:10.1002/anie.201411378 · Cited by 754 · see citing works

DNA Origami as a Carrier for Circumvention of Drug Resistance

Jiang, Q., Song, C., Nangreave, J., Liu, X., Lin, L., Qiu, D., Wang, Z., Zou, G., Liang, X., Yan, H., et al. (2012) · Journal of the American Chemical Society · doi:10.1021/ja304263n · Cited by 738 · see citing works

Expanding and reprogramming the genetic code

Chin, J. W. (2017) · Nature · doi:10.1038/nature24031 · Cited by 730 · see citing works

Programmable in situ amplification for multiplexed imaging of mRNA expression

Choi, H. M. T., Chang, J. Y., Trinh, L. A., Padilla, J. E., Fraser, S. E., & Pierce, N. A. (2010) · Nature Biotechnology · doi:10.1038/nbt.1692 · Cited by 720 · see citing works

Resurrecting the Ancestral Steroid Receptor: Ancient Origin of Estrogen Signaling

Thornton, J. W., Need, E. F., & Crews, D. P. (2003) · Science · doi:10.1126/science.1086185 · Cited by 700 · see citing works

Protein-retention expansion microscopy of cells and tissues labeled using standard fluorescent proteins and antibodies

Tillberg, P. W., Chen, F., Piatkevich, K. D., Zhao, Y., Yu, C.-C., English, B. P., Gao, L. A., Martorell, A. J., Suk, H., Yoshida, F., et al. (2016) · Nature Biotechnology · doi:10.1038/nbt.3625 · Cited by 673 · see citing works

DNA rendering of polyhedral meshes at the nanoscale

Benson, E., Mohammed, A., Gardell, J., Masich, S., Czeizler, E., Orponen, P., & Högberg, B. (2015) · Nature · doi:10.1038/nature14586 · Cited by 672 · see citing works

In Situ Transcription Profiling of Single Cells Reveals Spatial Organization of Cells in the Mouse Hippocampus

Shah, S., Lubeck, E., Zhou, W., & Cai, L. (2016) · Neuron · doi:10.1016/j.neuron.2016.10.001 · Cited by 671 · see citing works

DNA Origami as an In Vivo Drug Delivery Vehicle for Cancer Therapy

Zhang, Q., Jiang, Q., Li, N., Dai, L., Liu, Q. L., Song, L., Wang, J., Li, Y., Tian, J., Ding, B., et al. (2014) · ACS Nano · doi:10.1021/nn502058j · Cited by 648 · see citing works

An Enhanced System for Unnatural Amino Acid Mutagenesis in E. coli

Young, T. S., Ahmad, I., Yin, J., & Schultz, P. G. (2009) · Journal of Molecular Biology · doi:10.1016/j.jmb.2009.10.030 · Cited by 638 · see citing works

Next-Generation in Situ Hybridization Chain Reaction: Higher Gain, Lower Cost, Greater Durability

Choi, H. M. T., Beck, V. A., & Pierce, N. A. (2014) · ACS Nano · doi:10.1021/nn405717p · Cited by 634 · see citing works

In Situ Probing of Newly Synthesized Peptidoglycan in Live Bacteria with Fluorescent D ‐Amino Acids

Kuru, E., Hughes, V., Brown, P., Hall, E. A., Tekkam, S., Cava, F., de Pedro, M. A., Brun, Y. V., & VanNieuwenhze, M. S. (2012) · Angewandte Chemie International Edition · doi:10.1002/anie.201206749 · Cited by 629 · see citing works

Designer nanoscale DNA assemblies programmed from the top down

Veneziano, R., Ratanalert, S., Zhang, K., Zhang, F., Yan, H., Chiu, W., & Bathe, M. (2016) · Science · doi:10.1126/science.aaf4388 · Cited by 624 · see citing works

A semi-synthetic organism with an expanded genetic alphabet

Malyshev, D. A., Dhami, K., Lavergne, T., Chen, T., Dai, N., Foster, J. M., Junior, I. R. C., & Romesberg, F. E. (2014) · Nature · doi:10.1038/nature13314 · Cited by 614 · see citing works

Advances and Applications of Single-Cell Sequencing Technologies

Wang, Y., & Navin, N. E. (2015) · Molecular Cell · doi:10.1016/j.molcel.2015.05.005 · Cited by 610 · see citing works

Genome-wide inactivation of porcine endogenous retroviruses (PERVs)

Yang, L., Güell, M., Niu, D., George, H., Lesha, E., Grishin, D., Aach, J., Shrock, E. L., Xu, W., Poci, J., et al. (2015) · Science · doi:10.1126/science.aad1191 · Cited by 604 · see citing works

Involvement of the low‐density lipoprotein receptor‐related protein in the transcytosis of the brain delivery vector Angiopep‐2

Demeule, M., Currie, J., Bertrand, Y., Ché, C., Nguyen, T., Régina, A., Gabathuler, R., Castaigne, J., & Béliveau, R. (2008) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2008.05492.x · Cited by 557 · see citing works

High-throughput single-cell gene-expression profiling with multiplexed error-robust fluorescence in situ hybridization

Moffitt, J. R., Hao, J., Wang, G., Chen, K. H., Babcock, H. P., & Zhuang, X. (2016) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1612826113 · Cited by 557 · see citing works

Precise Manipulation of Chromosomes in Vivo Enables Genome-Wide Codon Replacement

Isaacs, F. J., Carr, P. A., Wang, H. H., Lajoie, M. J., Sterling, B., Kraal, L., Tolonen, A. C., Gianoulis, T. A., Goodman, D. B., Reppas, N. B., et al. (2011) · Science · doi:10.1126/science.1205822 · Cited by 550 · see citing works

Total Synthesis of a Functional Designer Eukaryotic Chromosome

Annaluru, N., Muller, H., MITCHELL, L. A., Ramalingam, S., Stracquadanio, G., Richardson, S. M., Dymond, J. S., Kuang, Z., Scheifele, L. Z., Cooper, E. M., et al. (2014) · Science · doi:10.1126/science.1249252 · Cited by 547 · see citing works

The N-End Rule in Bacteria

Tobias, J. W., Shrader, T. E., Rocap, G., & Varshavsky, A. J. (1991) · Science · doi:10.1126/science.1962196 · Cited by 542 · see citing works

Design of a synthetic yeast genome

Richardson, S., Mitchell, L., Stracquadanio, G., Yang, K., Dymond, J. S., DiCarlo, J., Lee, D., Huang, C., Chandrasegaran, S., Cai, Y.-Z., et al. (2017) · Science · doi:10.1126/science.aaf4557 · Cited by 536 · see citing works

Fluorescent in situ sequencing (FISSEQ) of RNA for gene expression profiling in intact cells and tissues

Lee, J. H., Daugharthy, E. R., Scheiman, J., Kalhor, R., Ferrante, T. C., Terry, R., Turczyk, B. M., Yang, J. L., Lee, H. S., Aach, J., et al. (2015) · Nature Protocols · doi:10.1038/nprot.2014.191 · Cited by 529 · see citing works

Virus-Inspired Membrane Encapsulation of DNA Nanostructures To Achieve In Vivo Stability

Perrault, S. D., & Shih, W. M. (2014) · ACS Nano · doi:10.1021/nn5011914 · Cited by 524 · see citing works

DNA Origami Delivery System for Cancer Therapy with Tunable Release Properties

Zhao, Y., SHAW, A. R., Zeng, X., Benson, E., Nyström, A. M., & Högberg, B. (2012) · ACS Nano · doi:10.1021/nn3022662 · Cited by 522 · see citing works

Spatially resolved transcriptomics and beyond

Crosetto, N., Bienko, M., & van Oudenaarden, A. (2015) · Nature Reviews Genetics · doi:10.1038/nrg3832 · Cited by 509 · see citing works

Oligolysine-based coating protects DNA nanostructures from low-salt denaturation and nuclease degradation

Ponnuswamy, N., Bastings, M. M. C., Nathwani, B., Ryu, J. H., Chou, L. Y. T., Vinther, M., Li, A. W., Anastassacos, F. M., Mooney, D. J., & Shih, W. M. (2017) · Nature Communications · doi:10.1038/ncomms15654 · Cited by 509 · see citing works

Designing logical codon reassignment – Expanding the chemistry in biology

Dumas, A., Lercher, L., Spicer, C. D., & Davis, B. G. (2014) · Chemical Science · doi:10.1039/c4sc01534g · Cited by 487 · see citing works

Expanding and Reprogramming the Genetic Code of Cells and Animals

Chin, J. W. (2014) · Annual Review of Biochemistry · doi:10.1146/annurev-biochem-060713-035737 · Cited by 476 · see citing works

Biocontainment of genetically modified organisms by synthetic protein design

Mandell, D. J., Lajoie, M. J., Mee, M. T., Takeuchi, R., Kuznetsov, G., Norville, J. E., Gregg, C. J., Stoddard, B. L., & Church, G. M. (2015) · Nature · doi:10.1038/nature14121 · Cited by 474 · see citing works

Single-cell systems biology by super-resolution imaging and combinatorial labeling

Lubeck, E., & Cai, L. (2012) · Nature Methods · doi:10.1038/nmeth.2069 · Cited by 462 · see citing works

‘Omic’ technologies: genomics, transcriptomics, proteomics and metabolomics

Horgan, R., & Kenny, L. C. (2011) · The Obstetrician & Gynaecologist · doi:10.1576/toag.13.3.189.27672 · Cited by 461 · see citing works

Translation Elongation Factor EF-P Alleviates Ribosome Stalling at Polyproline Stretches

Ude, S., Lassak, J., Starosta, A. L., Kraxenberger, T., Wilson, D. N., & Jung, K. (2012) · Science · doi:10.1126/science.1228985 · Cited by 460 · see citing works

Integrating ‘omic’ information: a bridge between genomics and systems biology

Ge, H., Walhout, A. J. M., & Vidal, M. (2003) · Trends in Genetics · doi:10.1016/j.tig.2003.08.009 · Cited by 434 · see citing works

Complex wireframe DNA origami nanostructures with multi-arm junction vertices

Zhang, F., Jiang, S., Wu, S., Li, Y., Mao, C., Liu, Y., & Yan, H. (2015) · Nature Nanotechnology · doi:10.1038/nnano.2015.162 · Cited by 415 · see citing works

Multilayer DNA Origami Packed on a Square Lattice

Ke, Y., Douglas, S. M., Liu, M., Sharma, J., Cheng, A., Leung, A., Liu, Y., Shih, W. M., & Yan, H. (2009) · Journal of the American Chemical Society · doi:10.1021/ja906381y · Cited by 414 · see citing works

Refactoring the nitrogen fixation gene cluster from Klebsiella oxytoca

Temme, K., Zhao, D., & Voigt, C. A. (2012) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1120788109 · Cited by 414 · see citing works

Nanoscale imaging of RNA with expansion microscopy

Chen, F., Wassie, A. T., Coté, A., Sinha, A., Alon, S., Asano, S. M., Daugharthy, E. R., Chang, J., Marblestone, A. H., Church, G. M., et al. (2016) · Nature Methods · doi:10.1038/nmeth.3899 · Cited by 411 · see citing works

Resurrecting ancient genes: experimental analysis of extinct molecules

Thornton, J. W. (2004) · Nature Reviews Genetics · doi:10.1038/nrg1324 · Cited by 399 · see citing works

Composability of regulatory sequences controlling transcription and translation in <i>Escherichia coli</i>

Kosuri, S., Goodman, D. B., Cambray, G., Mutalik, V. K., Gao, Y., Arkin, A. P., Endy, D., & Church, G. M. (2013) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1301301110 · Cited by 392 · see citing works

Iterative expansion microscopy

Chang, J., Chen, F., Yoon, Y., Jung, E. E., Babcock, H. P., Kang, J. S., Asano, S. M., Suk, H., Pak, N., Tillberg, P. W., et al. (2017) · Nature Methods · doi:10.1038/nmeth.4261 · Cited by 390 · see citing works

The N-End Rule Pathway

Tasaki, T., Sriram, S. M., Park, K. S., & Kwon, Y. T. (2012) · Annual Review of Biochemistry · doi:10.1146/annurev-biochem-051710-093308 · Cited by 382 · see citing works

High-throughput mapping of single-neuron projections by sequencing of barcoded RNA

Kebschull, J. M., Garcia da Silva, P., Reid, A. P., Peikon, I. D., Albeanu, D. F., & Zador, A. M. (2016) · Neuron · doi:10.1016/j.neuron.2016.07.036 · Cited by 376 · see citing works

Quantitative prediction of 3D solution shape and flexibility of nucleic acid nanostructures

Kim, D., Kilchherr, F., Dietz, H., & Bathe, M. (2011) · Nucleic Acids Research · doi:10.1093/nar/gkr1173 · Cited by 374 · see citing works

Production of Site-Specific Antibody–Drug Conjugates Using Optimized Non-Natural Amino Acids in a Cell-Free Expression System

Zimmerman, E. S., Heibeck, T. H., Gill, A., Li, X., Murray, C. J., Madlansacay, M. R., Tran, C., Uter, N. T., Yin, G., Rivers, P. J., et al. (2014) · Bioconjugate Chemistry · doi:10.1021/bc400490z · Cited by 367 · see citing works

Recoded organisms engineered to depend on synthetic amino acids

Rovner, A. J., Haimovich, A. D., Katz, S. R., Li, Z., Grome, M. W., Gassaway, B. M., Amiram, M., Patel, J. R., Gallagher, R. R., Rinehart, J., et al. (2015) · Nature · doi:10.1038/nature14095 · Cited by 366 · see citing works

CRISPR-Cas Encoding of a Digital Movie into the Genomes of a Population of Living Bacteria

Shipman, S. L., Nivala, J., Macklis, J. D., & Church, G. M. (2017) · Nature · doi:10.1038/nature23017 · Cited by 361 · see citing works

Scaffolded DNA Origami of a DNA Tetrahedron Molecular Container

Ke, Y., Sharma, J., Liu, M., Jahn, K., Liu, Y., & Yan, H. (2009) · Nano Letters · doi:10.1021/nl901165f · Cited by 343 · see citing works

Synthesis and Accumulation of Aromatic Aldehydes in an Engineered Strain of Escherichia coli

Kunjapur, A. M., Tarasova, Y., & Prather, K. L. J. (2014) · Journal of the American Chemical Society · doi:10.1021/ja506664a · Cited by 330 · see citing works

Folding and cutting DNA into reconfigurable topological nanostructures

Han, D., Pal, S., Liu, Y., & Yan, H. (2010) · Nature Nanotechnology · doi:10.1038/nnano.2010.193 · Cited by 329 · see citing works

High-performance multiplexed fluorescence in situ hybridization in culture and tissue with matrix imprinting and clearing

Moffitt, J. R., Hao, J., Bambah-Mukku, D., Lu, T., Dulac, C., & Zhuang, X. (2016) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1617699113 · Cited by 308 · see citing works

Assembly of a novel biosynthetic pathway for gentamicin B production in Micromonospora echinospora

Ni, X., Sun, Z., Gu, Y., Cui, H., & Xia, H. (2016) · Microbial Cell Factories · doi:10.1186/s12934-015-0402-6 · Cited by 291 · see citing works

Design, synthesis, and testing toward a 57-codon genome

Ostrov, N., Landon, M., Güell, M., Kuznetsov, G., Teramoto, J., Cervantes, N., Zhou, M. H., Singh, K., Napolitano, M. G., Moosburner, M., et al. (2016) · Science · doi:10.1126/science.aaf3639 · Cited by 289 · see citing works

Generation of a Bacterium with a 21 Amino Acid Genetic Code

Mehl, R. A., Anderson, J. C., Santoro, S. W., Wang, L., Martin, A., King, D., Horn, D. M., & Schultz, P. G. (2003) · Journal of the American Chemical Society · doi:10.1021/ja0284153 · Cited by 287 · see citing works

Rapid Folding of DNA into Nanoscale Shapes at Constant Temperature

Sobczak, J.-P. J., Martin, T. G., Gerling, T., & Dietz, H. (2012) · Science · doi:10.1126/science.1229919 · Cited by 285 · see citing works

Brain-targeting gene delivery and cellular internalization mechanisms for modified rabies virus glycoprotein RVG29 nanoparticles

Liu, Y., Huang, R., Han, L., Ke, W., Shao, K., Ye, L., Lou, J., & Jiang, C. (2009) · Biomaterials · doi:10.1016/j.biomaterials.2009.02.051 · Cited by 281 · see citing works

Mapping a multiplexed zoo of mRNA expression

Choi, H. M. T., Calvert, C. R., Husain, N., Huss, D. J., Barsi, J. C., Deverman, B. E., Hunter, R. C., Kato, M., Lee, S. M., Abelin, A. C. T., et al. (2016) · Development · doi:10.1242/dev.140137 · Cited by 271 · see citing works

DNA Gridiron Nanostructures Based on Four-Arm Junctions

Han, D., Pal, S., Yang, Y., Jiang, S., Nangreave, J., Liu, Y., & Yan, H. (2013) · Science · doi:10.1126/science.1232252 · Cited by 268 · see citing works

Partial d -amino acid substitution: Improved enzymatic stability and preserved Ab recognition of a MUC2 epitope peptide

Tugyi, R., Uray, K., Iván, D., et al. (2005) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0407677102 · Cited by 265 · see citing works

Facile and Scalable Preparation of Pure and Dense DNA Origami Solutions

Stahl, E., Martin, T. G., Praetorius, F., & Dietz, H. (2014) · Angewandte Chemie International Edition · doi:10.1002/anie.201405991 · Cited by 263 · see citing works

“Perfect” designer chromosome V and behavior of a ring derivative.

Xie, Z.-X., Li, B.-Z., Mitchell, L. A., Wu, Y., Qi, X., Jin, Z., Jia, B., Wang, X., Zeng, B.-X., Liu, H.-M., et al. (2017) · Science · doi:10.1126/science.aaf4704 · Cited by 255 · see citing works

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