Characterization of endosteal bone‐lining cells from fatty marrow bone sites in adult beagles
Abstract
Bone‐lining cells cover the majority of trabecular bone surfaces in adult long‐lived mammals. The morphology, ultrastructure, and population density of bone‐lining cells was investigated in several fatty marrow trabecular bone sites in adult beagles of different ages. Although there is a low population density of bone‐lining cells on bone surfaces, their total numbers greatly exceed the numbers of osteoblasts and osteoclasts found on these bone surfaces. In one of the bone sites studied, there are significantly fewer bone‐lining cells in very old beagles (12–16 years old) when compared to young adult beagles (1.5–3 years old), otherwise there are no differences in the cell population that could be attributed to aging. Bone‐lining cells are flattened against bone surfaces and have flat or sometimes ovoid‐shaped nuclei which are often located adjacent to areas in the fatty marrow where capillaries are found. When viewed in the electron microscope, bone‐lining cells contain few organelles, and the attenuated cytoplasm of these cells is well extended over bone surfaces. The bone‐lining cell cytoplasm does not appear to form a continuous layer over the bone surface, as numerous gaps and spaces are seen. Bone‐lining cell processes are frequently joined by junctions morphologically similar to gap junctions. Between the lamina limitans of the bone matrix and the bone‐lining cell, as well as between the bone‐lining cell and the adjacent fat cells, there are layers of connective tissue containing collagenous fibers and other amorphous material. These findings are discussed in relation to the possible role of bone‐lining cells in the regulation of mineral homeostasis.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
BLCs are a cell population that differs from both marrow cells and osteoblasts.
“BLCs are a cell population that differs from both marrow cells111 and osteoblasts.”
From Bone remodeling: an operational process ensuring survival and bone mechanical competence (2022) · cites this paper as [111]
Cites
THE CHEMICAL DYNAMICS OF BONE MINERAL
NEUMAN, W. F., & NEUMAN, M. W. (1959) · The American Journal Of The Medical Sciences · doi:10.1097/00000441-195912000-00030 · Cited by 1,032 · see citing works
Nelder, J. A., & Bliss, C. I. (1971) · Journal of the Royal Statistical Society Series A (General) · doi:10.2307/2343879 · Cited by 760 · see citing works
Membrane ultrastructure at mammalian intercellular junctions
McNutt, N. S., & Weinstein, R. S. (1973) · Progress in Biophysics and Molecular Biology · doi:10.1016/0079-6107(73)90017-5 · Cited by 514 · see citing works
A Simple Methylene Blue-Azure Ii-Basic Fuchsin Stain for Epoxy-Embedded Tissue Sections
Humphrey, C. D., & Pittman, F. E. (1974) · Stain Technology · doi:10.3109/10520297409116929 · Cited by 510 · see citing works
Mechanisms of calcification: role of collagen, polyphosphates, and phosphatase
Fleish, H., & Neuman, W. F. (1961) · American Journal of Physiology-Legacy Content · doi:10.1152/ajplegacy.1961.200.6.1296 · Cited by 444 · see citing works
Calcium, Parathyroid Hormone and the Calcitonins
Chalmers, J. P. (1973) · Journal of Bone and Joint Surgery - British Volume · doi:10.1302/0301-620x.55b4.892 · Cited by 413 · see citing works
Anderson, C. (1994) · Bone and Mineral · doi:10.1016/s0169-6009(08)80063-3 · Cited by 258 · see citing works
A quantitative histological study on bone resorption in human cancellous bone
Schenk, R., Merz, W. A., & Müller, J. (2008) · Acta Anatomica · doi:10.1159/000143361 · Cited by 214 · see citing works
A quantitative histological study on bone formation in human cancellous bone
Merz, W. A., & Schenk, R. (1970) · Cells Tissues Organs · doi:10.1159/000143476 · Cited by 150 · see citing works
Pyrophosphate and Diphosphonates in Skeletal Metabolism
Russell, R. G. G., & Fleisch, H. (1975) · Clinical Orthopaedics and Related Research · doi:10.1097/00003086-197505000-00038 · Cited by 140 · see citing works
Submicroscopic structure and functional aspects of the osteocyte.
BAUD, C. A. (1968) · PubMed · Cited by 135 · see citing works
The lamina limitans of the organic matrix of calcified cartilage and bone
Scherft, J. P. (1972) · Journal of Ultrastructure Research · doi:10.1016/s0022-5320(72)90008-1 · Cited by 121 · see citing works
CALCIUM AND PHOSPHORUS IN THE SERUM IN RELATION TO RICKETS
HOWLAND, J., & Krämer, B. (1921) · Archives of Pediatrics and Adolescent Medicine · doi:10.1001/archpedi.1921.04120020002001 · Cited by 115 · see citing works
Ethane-1-hydroxy-1, 1-diphosphonate (EHDP) effects on growth and modeling of the rat tibia
Miller, S. C., & Jee, W. S. S. (1975) · Calcified Tissue International · doi:10.1007/bf02546241 · Cited by 112 · see citing works
Self-citationMorphological and physiological considerations in a new concept of calcium transport in bone
Talmage, R. V. (1970) · American Journal of Anatomy · doi:10.1002/aja.1001290408 · Cited by 108 · see citing works
Weinger, J. M., & Holtrop, M. E. (1974) · Calcified Tissue International · doi:10.1007/bf02060280 · Cited by 101 · see citing works
Fine structure of the osteocyte capsule and of the wall of the lacunae in bone
Wassermann, F., & Yaeger, J. A. (1965) · Cell and Tissue Research · doi:10.1007/bf00340329 · Cited by 90 · see citing works
Submicroscopic Structure and Functional Aspects of the Osteocyte*
BAUD, C. A. (1968) · Clinical Orthopaedics and Related Research · doi:10.1097/00003086-196801000-00025 · Cited by 81 · see citing works
Potassium and milieu interieur of bone
Cañas, F. M., TEREPKA, A. R., & Neuman, W. F. (1969) · American Journal of Physiology-Legacy Content · doi:10.1152/ajplegacy.1969.217.1.117 · Cited by 68 · see citing works
Wronski, T. J., Smith, J. M., & Jee, W. S. S. (1980) · Radiation Research · doi:10.2307/3575260 · Cited by 63 · see citing works
Self-citationNeuman, W. F., & Ramp, W. K. (1971) · Elsevier eBooks · doi:10.1016/b978-0-12-518050-4.50017-3 · Cited by 61 · see citing works
Talmage, R. V., Doppelt, S. H., & Fondren, F. B. (1977) · Calcified Tissue International · doi:10.1007/bf02010351 · Cited by 51 · see citing works
Occurrence of cell junctions and microfilaments in osteoblasts
STANKA, P. (1975) · Cell and Tissue Research · doi:10.1007/bf00221787 · Cited by 46 · see citing works
Dougherty, T. F., Stover, B. J., Dougherty, J. H., Jee, W. S. S., Mays, C. W., Rehfeld, C. E., Christensen, W. R., & Goldthorpe, H. C. (1962) · Radiation Research · doi:10.2307/3571189 · Cited by 43 · see citing works
Self-citationTight Junction Formation in the Osteon
Whitson, S. W. (1972) · Clinical Orthopaedics and Related Research · doi:10.1097/00003086-197207000-00032 · Cited by 32 · see citing works
Calcium transport systems in the chick calvaria
Neuman, W. F., Mulryan, B. J., Neuman, M. R., & Lane, K. (1973) · American Journal of Physiology-Legacy Content · doi:10.1152/ajplegacy.1973.224.3.600 · Cited by 20 · see citing works
The Presence of Lining Cells on Surfaces of Human Trabecular Bone
Wiel, C. J. V., Grubb, S. A., & Talmage, R. V. (1978) · Clinical Orthopaedics and Related Research · doi:10.1097/00003086-197807000-00053 · Cited by 19 · see citing works
Norimatsu, H., Wiel, C. J. V., & Talmage, R. V. (1979) · PubMed · Cited by 19 · see citing works
Flagged first, then by citations
Cited by
Sorted by citations
Parfitt, A. M. (1994) · Journal of Cellular Biochemistry · doi:10.1002/jcb.240550303 · Cited by 1,001 · see citing works
Buried alive: How osteoblasts become osteocytes
Franz‐Odendaal, T. A., Hall, B. K., & Witten, P. E. (2006) · Developmental Dynamics · doi:10.1002/dvdy.20603 · Cited by 795 · see citing works
Bone remodeling: an operational process ensuring survival and bone mechanical competence
Bolamperti, S., Villa, I., & Rubinacci, A. (2022) · Bone Research · doi:10.1038/s41413-022-00219-8 · Cited by 482 · see citing works
Bone cell biology: The regulation of development, structure, and function in the skeleton
Marks, S. C., & Popoff, S. N. (1988) · American Journal of Anatomy · doi:10.1002/aja.1001830102 · Cited by 471 · see citing works
Parfitt, A. M. (1984) · Calcified Tissue International · doi:10.1007/bf02406132 · Cited by 406 · see citing works
Hauge, E. M., Qvesel, D., Eriksen, E. F., Mosekilde, L., & Melsen, F. (2001) · Journal of Bone and Mineral Research · doi:10.1359/jbmr.2001.16.9.1575 · Cited by 397 · see citing works
Raisz, L. G., & Kream, B. E. (1983) · New England Journal of Medicine · doi:10.1056/nejm198307073090107 · Cited by 339 · see citing works
Molecular and cellular biology of alveolar bone
SODEK, J., & MCKEE, M. D. (2000) · Periodontology 2000 · doi:10.1034/j.1600-0757.2000.2240106.x · Cited by 283 · see citing works
Ultrastructural analysis of bone nodules formed in vitro by isolated fetal rat calvaria cells
Bhargava, U., Bar-Lev, M., Bellows, C. G., & Aubin, J. E. (1988) · Bone · doi:10.1016/8756-3282(88)90005-1 · Cited by 279 · see citing works
Basis of bone metabolism around dental implants during osseointegration and peri‐implant bone loss
Ínsua, Á., Monje, A., Wang, H., & Miron, R. J. (2017) · Journal of Biomedical Materials Research Part A · doi:10.1002/jbm.a.36060 · Cited by 278 · see citing works
Morphological study of intercellular junctions during osteocyte differentiation
Palumbo, C., Palazzini, S., & Marotti, G. (1990) · Bone · doi:10.1016/8756-3282(90)90134-k · Cited by 252 · see citing works
Regulation of Bone Remodeling by Parathyroid HormonePreprint
Wein, M. N., & Kronenberg, H. M. (2018) · Cold Spring Harbor Perspectives in Medicine · doi:10.1101/cshperspect.a031237 · Cited by 243 · see citing works
Differentiation of Osteoblasts and Osteocytes from Mesenchymal Stem Cells
Heino, T. J., & Hentunen, T. A. (2008) · Current Stem Cell Research & Therapy · doi:10.2174/157488808784223032 · Cited by 218 · see citing works
OSCAR is a collagen receptor that costimulates osteoclastogenesis in DAP12-deficient humans and mice
Barrow, A. D., Raynal, N., Andersen, T. L., Slatter, D. A., Bihan, D. G., Pugh, N., Cella, M., Kim, T. S., Rho, J., Negishi‐Koga, T., et al. (2011) · Journal of Clinical Investigation · doi:10.1172/jci45913 · Cited by 207 · see citing works
Delaissé, J. (2014) · BoneKEy Reports · doi:10.1038/bonekey.2014.56 · Cited by 168 · see citing works
Integrated Bone Tissue Physiology
Jee, W. S. S. (2001) · CRC Press eBooks · doi:10.1201/b14263-3 · Cited by 163 · see citing works
Self-citationRe-thinking the bone remodeling cycle mechanism and the origin of bone loss
Delaisse, J.-M., Andersen, T. L., Kristensen, H. B., Jensen, P. R., Andreasen, C. M., & Søe, K. (2020) · Bone · doi:10.1016/j.bone.2020.115628 · Cited by 152 · see citing works
Aubin, J. E., Turksen, K., & Heersche, J. N. M. (1993) · Elsevier eBooks · doi:10.1016/b978-0-08-092500-4.50005-x · Cited by 149 · see citing works
The bone lining cell: A distinct phenotype?
Miller, S. C., & Jee, W. S. S. (1987) · Calcified Tissue International · doi:10.1007/bf02555122 · Cited by 143 · see citing works
Self-citationOvarian Aging and Osteoporosis
Li, L., & Wang, Z. (2018) · Advances in experimental medicine and biology · doi:10.1007/978-981-13-1117-8_13 · Cited by 138 · see citing works
Chow, J. W. M., Wilson, A., Chambers, T. J., & Fox, S. W. (1998) · Journal of Bone and Mineral Research · doi:10.1359/jbmr.1998.13.11.1760 · Cited by 120 · see citing works
Endogenous Ionic Currents Traverse Intact and Damaged Bone
Borgens, R. B. (1984) · Science · doi:10.1126/science.6740320 · Cited by 119 · see citing works
Rouleau, M. F., Mitchell, J., & Goltzman, D. (1990) · Journal of Bone and Mineral Research · doi:10.1002/jbmr.5650051008 · Cited by 111 · see citing works
What is the true nature of the osteoblastic hematopoietic stem cell niche?
Askmyr, M., Sims, N. A., Martin, T. J., & Purton, L. E. (2009) · Trends in Endocrinology and Metabolism · doi:10.1016/j.tem.2009.03.004 · Cited by 99 · see citing works
Skeletal function and structure: Implications for tissue-targeted therapeutics
Shea, J., & Miller, S. C. (2005) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2004.12.017 · Cited by 98 · see citing works
Self-citationOsteoblast Recruitment Routes in Human Cancellous Bone Remodeling
Kristensen, H. B., Andersen, T. L., Marcussen, N., Rolighed, L., & Delaissé, J. (2014) · American Journal Of Pathology · doi:10.1016/j.ajpath.2013.11.022 · Cited by 88 · see citing works
Medullary bone osteogenesis following estrogen administration to mature male Japanese quail
Miller, S. C., & Bowman, B. M. (1981) · Developmental Biology · doi:10.1016/0012-1606(81)90060-9 · Cited by 72 · see citing works
Self-citationFrom bone lining cell to osteocyte—an SEM study
Menton, D. N., Simmons, D. J., Chang, S. ‐., & Orr, B. Y. (1984) · The Anatomical Record · doi:10.1002/ar.1092090105 · Cited by 67 · see citing works
Martin, T. J., Ng, K. W., & Nicholson, G. C. (1988) · PubMed · Cited by 66 · see citing works
Shapiro, F. (1997) · Calcified Tissue International · doi:10.1007/s002239900337 · Cited by 59 · see citing works
Transitional structures in lamellar bone
Ziv, V., Sabanay, I., Arad, T., Traub, W., & Weiner, S. (1996) · Microscopy Research and Technique · doi:10.1002/(sici)1097-0029(19960201)33:2 · Cited by 55 · see citing works
Cellular and Molecular Mechanisms in the Regulation and Function of Osteoclasts
Chambers, T. J., & Hall, T. J. (1991) · Vitamins and hormones · doi:10.1016/s0083-6729(08)60682-2 · Cited by 57 · see citing works
Li, M., Liang, H., Shen, Y., & Wronski, T. J. (1999) · Bone · doi:10.1016/s8756-3282(98)00167-7 · Cited by 56 · see citing works
Comparative study of skeletal response to estrogen depletion at red and yellow marrow sites in rats
Li, M., Shen, Y., Qi, H., & Wronski, T. (1996) · The Anatomical Record · doi:10.1002/(sici)1097-0185(199607)245:3 · Cited by 61 · see citing works
PARFITT, A. M. (1993) · Handbook of experimental pharmacology · doi:10.1007/978-3-642-77991-6_1 · Cited by 54 · see citing works
Chiba, H., Sawada, N., Oyamada, M., Kojima, T., Nomura, S., Ishii, S., & Mori, M. (1993) · Cell Structure and Function · doi:10.1247/csf.18.419 · Cited by 53 · see citing works
The Osteocyte: From “Prisoner” to “Orchestrator”
Palumbo, C., & Ferretti, M. (2021) · Journal of Functional Morphology and Kinesiology · doi:10.3390/jfmk6010028 · Cited by 49 · see citing works
Cancellous bone minimodeling-based formation: a Frost, Takahashi legacy.
Jee, W. S. S., Tian, X. Y., & Setterberg, R. B. (2007) · PubMed · Cited by 47 · see citing works
Self-citationLozupone, E., Palumbo, C., Favia, A., Ferretti, M., Palazzini, S., & Cantatore, F. P. (1996) · Clinical Rheumatology · doi:10.1007/bf02238545 · Cited by 47 · see citing works
Miller, S. C., Bowman, B. M., & Myers, R. L. (1984) · The Anatomical Record · doi:10.1002/ar.1092080209 · Cited by 46 · see citing works
Self-citationBone lining cells and hematopoiesis: An electron microscopic study of canine bone marrow
Deldar, A., WEISS, L. P., & Lewis, H. B. (1985) · The Anatomical Record · doi:10.1002/ar.1092130211 · Cited by 46 · see citing works
Chiba, H., Sawada, N., Oyamada, M., Kojima, T., Iba, K., Ishii, S., & Mori, M. (1994) · Cell Structure and Function · doi:10.1247/csf.19.173 · Cited by 43 · see citing works
The micocirculation of bone and marrow in the diaphysis of the rat hemopoietic long bones
de Saint‐Georges, L., & Miller, S. C. (1992) · The Anatomical Record · doi:10.1002/ar.1092330202 · Cited by 42 · see citing works
Self-citationThe proliferation and differentiation of the bone-lining cell in estrogen-induced osteogenesis
Bowman, B. M., & Miller, S. C. (1986) · Bone · doi:10.1016/8756-3282(86)90255-3 · Cited by 41 · see citing works
Self-citationHughes, D. R., Bassett, J. R., & Moffat, L. (1994) · Anatomy and Embryology · doi:10.1007/bf00193413 · Cited by 35 · see citing works
Martin, T. J., Ng, K. W., & Nicholson, G. C. (1988) · Baillière s Clinical Endocrinology and Metabolism · doi:10.1016/s0950-351x(88)80006-5 · Cited by 34 · see citing works
Pun, S., Dearden, R. L., Ratkus, A. M., Liang, H., & Wronski, T. J. (2001) · Bone · doi:10.1016/s8756-3282(00)00423-3 · Cited by 34 · see citing works
Bone as an ion exchange system: evidence for a link between mechanotransduction and metabolic needs
Rubinacci, A., Covini, M., Bisogni, C., Villa, I., Galli, M., Palumbo, C., Ferretti, M., Muglia, M. A., & Marotti, G. (2002) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00367.2001 · Cited by 32 · see citing works
Islam, A., Glomski, C. A., & Henderson, E. S. (1990) · The Anatomical Record · doi:10.1002/ar.1092270304 · Cited by 32 · see citing works
A comparative study of perichondrial tissue in mammalian cartilages
Bairati, A., Comazzi, M., & Gioria, M. (1996) · Tissue and Cell · doi:10.1016/s0040-8166(96)80031-0 · Cited by 31 · see citing works
Terakado, A., Tagawa, M., Goto, S., Yamazaki, M., Moriya, H., & Fujimura, S. (1995) · Calcified Tissue International · doi:10.1007/bf00296345 · Cited by 30 · see citing works
Transmission electron microscopy of bone tissue: A review
Boivin, G., Anthoine-Terrier, C., & Obrant, K. J. (1990) · Acta Orthopaedica Scandinavica · doi:10.3109/17453679009006514 · Cited by 29 · see citing works
A cellular investment of bone marrow
Menton, D. N., Simmons, D. J., Orr, B. Y., & Plurad, S. B. (1982) · The Anatomical Record · doi:10.1002/ar.1092030114 · Cited by 29 · see citing works
Doty, S. B., & Nunez, E. A. (1985) · The Anatomical Record · doi:10.1002/ar.1092130403 · Cited by 27 · see citing works
Bone Lining Cells: Normal Physiology and Role in Response to Anabolic Osteoporosis Treatments
Wein, M. N. (2017) · Current Molecular Biology Reports · doi:10.1007/s40610-017-0062-x · Cited by 25 · see citing works
The microvascular bed of fatty bone marrow in the adult beagle
Miller, S. C., & Jee, W. S. S. (1980) · Metabolic Bone Disease and Related Research · doi:10.1016/0221-8747(80)90013-2 · Cited by 24 · see citing works
Self-citationBone mechanobiology in health and disease
Verbruggen, S. W., & McNamara, L. M. (2018) · Elsevier eBooks · doi:10.1016/b978-0-12-812952-4.00006-4 · Cited by 23 · see citing works
Regelsberger, J., Milovanovic, P. D., Schmidt, T., Hahn, M. P., Zimmermann, E., Tsokos, M., Zustin, J., Ritchie, R. O., Amling, M., & Busse, B. (2012) · European Cells and Materials · doi:10.22203/ecm.v024a31 · Cited by 23 · see citing works
An assessment of the prevalence of organic material on bone surfaces
Chow, J. W. M., & Chambers, T. J. (1992) · Calcified Tissue International · doi:10.1007/bf00298787 · Cited by 23 · see citing works
Nishino, I., Amizuka, N., & Ozawa, H. (2001) · Journal of Bone and Mineral Metabolism · doi:10.1007/s007740170010 · Cited by 22 · see citing works
Physiological and Pharmacological Regulation of Biological Calcification
Williams, D. C., & Frolik, C. A. (1991) · International review of cytology · doi:10.1016/s0074-7696(08)60685-3 · Cited by 22 · see citing works
Pazzaglia, U. E., Congiu, T., Sibilia, V., & Quacci, D. E. (2013) · Journal of Anatomy · doi:10.1111/joa.12138 · Cited by 19 · see citing works
A Critical Role of the Bone Marrow Envelope in Human Bone Remodeling
Andersen, T. L., Jensen, P. R., Sikjær, T., Rejnmark, L., Ejersted, C., & Delaissé, J. (2020) · Journal of Bone and Mineral Research · doi:10.1002/jbmr.4815 · Cited by 20 · see citing works
Yamazaki, K., & Eyden, B. P. (1995) · Anatomy and Embryology · doi:10.1007/bf00186987 · Cited by 20 · see citing works
Sun, X., Kishore, V., Fites, K., & Akkuş, O. (2012) · Bone · doi:10.1016/j.bone.2012.08.116 · Cited by 18 · see citing works
Cell Structure and Biology of Bone and Cartilage
Walsh, W. R., Walton, M., Bruce, W. J. M., Yu, Y. Y., Gillies, R. M., & Svehla, M. (2003) · Humana Press eBooks · doi:10.1007/978-1-59259-417-7_2 · Cited by 17 · see citing works
Bicarbonate Dependence of Ion Current in Damaged Bone
Rubinacci, A., Ponti, A. D., Shipley, A. M., Samaja, M., Karplus, E., & Jaffe, L. F. (1996) · Calcified Tissue International · doi:10.1007/bf02509442 · Cited by 15 · see citing works
Catabolic Properties of Microdissected Human Endosteal Bone Lining Cells
Dierkes, C., Kreisel, M., Schulz, A., Steinmeyer, J., Wolff, J.-C., & Fink, L. (2009) · Calcified Tissue International · doi:10.1007/s00223-008-9213-7 · Cited by 15 · see citing works
Bone Morphology and Postnatal Osteogenesis
Kincaid, S. A., & Sickle, D. C. V. (1983) · Veterinary Clinics of North America Small Animal Practice · doi:10.1016/s0195-5616(83)50001-6 · Cited by 15 · see citing works
Herbert, B., Lecouturier, A., Masquelier, D., Hauser, N., & Remacle, C. (1997) · Calcified Tissue International · doi:10.1007/s002239900217 · Cited by 14 · see citing works
Incomplete Coverage of Mammalian Bone Matrix by Lining Cells
Chole, R. A., & Tinling, S. P. (1993) · Annals of Otology Rhinology & Laryngology · doi:10.1177/000348949310200710 · Cited by 14 · see citing works
Rubinacci, A., Benelli, F. D., Borgo, E., & Villa, I. (2000) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.2000.278.1.e15 · Cited by 13 · see citing works
Bone cell populations and histomorphometric correlates to function
Simmons, D. J., Menton, D. N., Russell, J. E., Smith, R., & Walker, W. V. (1988) · The Anatomical Record · doi:10.1002/ar.1092220303 · Cited by 13 · see citing works
Periosteal Attachment Fibers in the Rat Calvarium
Simmons, D. J., Menton, D. N., Miller, S., & Lozano, R. (1993) · Calcified Tissue International · doi:10.1007/bf03549786 · Cited by 11 · see citing works
Self-citationCellular isolation, culture and characterization of the marrow sac cells in human tubular bone.
Bi, L. X., Mainous, E. G., Yngve, D. A., & Buford, W. L. (2008) · PubMed · Cited by 10 · see citing works
Histology, Periosteum And Endosteum
Nahian, A., & Chauhan, P. (2021) · StatPearls · Cited by 10 · see citing works
Kidney and Bone: Physiological and Pathophysiological Relationships
Brown, E. M. (1992) · Comprehensive physiology · doi:10.1002/cphy.cp080239 · Cited by 9 · see citing works
The Distribution of Radium and Plutonium in Human Bone
Schlenker, R. A. (1985) · Springer eBooks · doi:10.1007/978-94-009-4920-1_13 · Cited by 8 · see citing works
Bairati, A., Comazzi, M., & Gioria, M. (1995) · Tissue and Cell · doi:10.1016/s0040-8166(05)80060-6 · Cited by 7 · see citing works
Inner ear basic fibroblast growth factor in CBA/J, C3H/HeJ, and autoimmune Palmerston North mice
Pedersen, A. D., Morton, J. I., & Trune, D. R. (1993) · Hearing Research · doi:10.1016/0378-5955(93)90145-q · Cited by 7 · see citing works
Loading of cells and a possible upper limit of load response with respect to strain energy density
McDonald, F., & Yettram, A. L. (1995) · Journal of Biomedical Materials Research · doi:10.1002/jbm.820291214 · Cited by 4 · see citing works
Tian, X. Y., Liu, X. Q., Chen, H. Y., Setterberg, R. B., Li, M., & Jee, W. S. S. (2008) · PubMed · Cited by 4 · see citing works
Self-citationYasuda, H., Tanabe, K., Satô, T., Nomoto, S., Miura, T., & Yoshinari, M. (2014) · Journal of Hard Tissue Biology · doi:10.2485/jhtb.23.389 · Cited by 3 · see citing works
Miller, S. C. (2025) · The Anatomical Record · doi:10.1002/ar.25641 · Cited by 2 · see citing works
Self-citationTian, X., Chen, H. Y., Setterberg, R. B., Li, M., & Jee, W. S. S. (2009) · PubMed · Cited by 2 · see citing works
Self-citationMechanobiological Origins of Osteoporosis
Verbruggen, S. W. (2013) · Arrow@dit (Dublin Institute of Technology) · doi:10.13025/17164 · Cited by 2 · see citing works
Pea Protein Derived Bioactive Peptides Stimulate Bone Health Promoting Effects
Arora, H. (2020) · ERA: Education and Research Archive (University of Alberta) · doi:10.7939/r3-ws1n-gp07 · Cited by 2 · see citing works
Lozupone, E., Palumbo, C., Favia, A., Ferretti, M., & Palazzini, S. (1996) · Cited by 1 · see citing works
Visualizing Normal and Malignant Human Stem and Progenitor Cells in Histological Sections
Kristensen, H. B., Patriarca, A., & Delaissé, J. (2020) · Elsevier eBooks · doi:10.1016/b978-0-12-801238-3.11159-6 · Cited by 1 · see citing works
Efeito do cálcio extracelular na osteogénese através da regulação do calcium sensing receptor
Rego, L. C. F. F. D. N. (2005)
Rueger, J. M. (1992) · Springer eBooks · doi:10.1007/978-3-642-76585-8_10
Kidney and Bone: Physiological and Pathophysiological Relationships
Brown, E. M. (1991) · Comprehensive physiology · doi:10.1002/j.2040-4603.1991.tb01596.x
The role of maternal omega-3 supplementation in shaping offspring skeletal health
Chakraborty, A., Usharani, D., & Sharan, K. (2025) · Elsevier eBooks · doi:10.1016/b978-0-443-19116-9.00037-3
Jahani, M. (2012) · Repository@Hull (Worktribe) (University of Hull)
- Authors
- Miller, S. C., Bowman, B. M., Smith, J. M., & Jee, W. S. S.
- Affiliations
- University of Utah (US)
- ORCID
- Miller, Scott C.
- Venue
- The Anatomical Record
- Publisher
- Wiley
- Published
- 1980-10
- Volume
- 198
- Issue
- 2
- Pages
- 163-173
- ISSN
- 0003-276X (ISSN-L)
- 1097-0185
- OpenAlex
- W2168002240
- Cited by
- 98
- References
- 28
- Citations by year
- 2025: 2 · 2022: 1 · 2021: 2 · 2020: 4 · 2019: 1 · 2018: 3 · 2017: 2 · 2014: 3 · 2013: 3 · 2012: 3
- FWCI
- 0.92
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- The Anatomical Record (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Bone Metabolism and Diseases
- Health Sciences › Medicine › Orthopedics and Sports Medicine › Bone health and osteoporosis research
- Health Sciences › Medicine › Urology › Comparative Animal Anatomy Studies
- Keywords
- bone lining cells, trabecular bone, beagle dogs, aging, ultrastructure, cell morphology, gap junctions, mineral homeostasis, bone surface, osteoblasts, osteoclasts
- MeSH terms
- Aging, Animals, Bone and Bones, Bone Marrow, Cell Count, Connective Tissue, Dogs, Intercellular Junctions, Organoids
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
