Cited by 61Obsessive-Compulsive Spectrum DisordersAutism Spectrum Disorder ResearchPsychoanalysis and Psychopathology Research

Obsessive-compulsive disorder in adults with high-functioning autism spectrum disorder: what does self-report with the OCI-R tell us?

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Cadman, Tim, Spain, Debbie, Johnston, Patrick, Russell, Ailsa, Mataix‐Cols, David, Craig, Michael, Deeley, Quinton, Robertson, Dene +11 more·2015·Autism Research

Abstract

Little is known about the symptom profile of obsessive-compulsive disorder (OCD) in individuals who have autism spectrum disorders (ASD). It is also unknown whether self-report questionnaires are useful in measuring OCD in ASD. We sought to describe the symptom profiles of adults with ASD, OCD, and ASD + OCD using the Obsessive Compulsive Inventory-Revised (OCI-R), and to assess the utility of the OCI-R as a screening measure in a high-functioning adult ASD sample. Individuals with ASD (n = 171), OCD (n = 108), ASD + OCD (n = 54) and control participants (n = 92) completed the OCI-R. Individuals with ASD + OCD reported significantly higher levels of obsessive-compulsive symptoms than those with ASD alone. OCD symptoms were not significantly correlated with core ASD repetitive behaviors as measured on the ADI-R or ADOS-G. The OCI-R showed good psychometric properties and corresponded well with clinician diagnosis of OCD. Receiver operating characteristic analysis suggested cut-offs for OCI-R Total and Checking scores that discriminated well between ASD + versus -OCD, and fairly well between ASD-alone and OCD-alone. OCD manifests separately from ASD and is characterized by a different profile of repetitive thoughts and behaviors. The OCI-R appears to be useful as a screening tool in the ASD adult population.

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Crossref · 10.1002/aur.1461

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Authors
Cadman, T., Spain, D., Johnston, P., Russell, A., Mataix‐Cols, D., Craig, M., Deeley, Q., Robertson, D., Murphy, C., Gillan, N., Wilson, C. E., Mendez, M., Ecker, C., Daly, E., Findon, J., Glaser, K., MRC AIMS Consortium, Happé, F., & Murphy, D.
Affiliations
  • King's College London (GB)
  • University of Bath (GB)
  • Sackler Institute for Translational Neurodevelopment and Department of Forensic and Neurodevelopmental Sciences, King's College London, Institute of Psychiatry, Psychology & Neuroscience London UK
  • MRC Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology & Neuroscience, King's College London UK
Corresponding author
Spain, Debbie
Venue
Autism Research
Publisher
Wiley
Published
2015-02-07
Volume
8
Issue
5
Pages
477-485
ISSN
  • 1939-3792 (ISSN-L)
  • 1939-3806
OpenAlex
W1855444725
Cited by
61
References
41
Citations by year
2026: 1 · 2025: 2 · 2024: 10 · 2023: 3 · 2022: 6 · 2021: 6 · 2020: 6 · 2019: 4 · 2018: 4 · 2017: 8 · 2016: 5 · 2015: 6
FWCI
9.52
Type
journal article
Language
en
Locations
  • Autism Research (publishedVersion)
  • PubMed (publishedVersion)
  • Bristol Research (University of Bristol) (publishedVersion)
  • Research Bank (Australian Catholic University) (submittedVersion)
  • UCL Discovery (University College London) (submittedVersion)
  • Research Portal (King's College London) (submittedVersion)
  • The University of Bath Online Publications Store (The University of Bath) (submittedVersion)
  • Pure (University of Bath) (submittedVersion, other-oa)
  • Explore Bristol Research (submittedVersion)
Funders
Medical Research Council (G0400061/69344)
Topics
  • Social Sciences › Psychology › Clinical Psychology › Obsessive-Compulsive Spectrum Disorders
  • Life Sciences › Neuroscience › Cognitive Neuroscience › Autism Spectrum Disorder Research
  • Social Sciences › Psychology › Clinical Psychology › Psychoanalysis and Psychopathology Research
Keywords
obsessive-compulsive disorder, autism spectrum disorder, high-functioning autism, adults, Obsessive-Compulsive Inventory-Revised, self-report screening, comorbidities, repetitive behavior, psychometric properties, diagnostic thresholds
MeSH terms
Autism Spectrum Disorder, Adult, Female, Humans, Male, Obsessive-Compulsive Disorder, Psychiatric Status Rating Scales, Psychometrics, Surveys and Questionnaires, Severity of Illness Index, Reproducibility of Results, Self Report

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