Obsessive-compulsive disorder in adults with high-functioning autism spectrum disorder: what does self-report with the OCI-R tell us?
Open accessAbstract
Little is known about the symptom profile of obsessive-compulsive disorder (OCD) in individuals who have autism spectrum disorders (ASD). It is also unknown whether self-report questionnaires are useful in measuring OCD in ASD. We sought to describe the symptom profiles of adults with ASD, OCD, and ASD + OCD using the Obsessive Compulsive Inventory-Revised (OCI-R), and to assess the utility of the OCI-R as a screening measure in a high-functioning adult ASD sample. Individuals with ASD (n = 171), OCD (n = 108), ASD + OCD (n = 54) and control participants (n = 92) completed the OCI-R. Individuals with ASD + OCD reported significantly higher levels of obsessive-compulsive symptoms than those with ASD alone. OCD symptoms were not significantly correlated with core ASD repetitive behaviors as measured on the ADI-R or ADOS-G. The OCI-R showed good psychometric properties and corresponded well with clinician diagnosis of OCD. Receiver operating characteristic analysis suggested cut-offs for OCI-R Total and Checking scores that discriminated well between ASD + versus -OCD, and fairly well between ASD-alone and OCD-alone. OCD manifests separately from ASD and is characterized by a different profile of repetitive thoughts and behaviors. The OCI-R appears to be useful as a screening tool in the ASD adult population.
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Rai, D., Webb, D., Lewis, A. L., Cotton, L., Norris, J. E., Alexander, R., Baldwin, D. S., Brugha, T. S., Cochrane, M., Piccolo, M. C. D., et al. (2024) · Figshare · doi:10.6084/m9.figshare.24987949
Self-citationRai, D., Webb, D., Lewis, A. L., Cotton, L., Norris, J. E., Alexander, R., Baldwin, D. S., Brugha, T. S., Cochrane, M., Piccolo, M. C. D., et al. (2024) · Figshare · doi:10.6084/m9.figshare.24987702
Self-citation
- Authors
- Cadman, T., Spain, D., Johnston, P., Russell, A., Mataix‐Cols, D., Craig, M., Deeley, Q., Robertson, D., Murphy, C., Gillan, N., Wilson, C. E., Mendez, M., Ecker, C., Daly, E., Findon, J., Glaser, K., MRC AIMS Consortium, Happé, F., & Murphy, D.
- Affiliations
- King's College London (GB)
- University of Bath (GB)
- Sackler Institute for Translational Neurodevelopment and Department of Forensic and Neurodevelopmental Sciences, King's College London, Institute of Psychiatry, Psychology & Neuroscience London UK
- MRC Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology & Neuroscience, King's College London UK
- Corresponding author
- Spain, Debbie
- ORCID
- Venue
- Autism Research
- Publisher
- Wiley
- Published
- 2015-02-07
- Volume
- 8
- Issue
- 5
- Pages
- 477-485
- ISSN
- 1939-3792 (ISSN-L)
- 1939-3806
- OpenAlex
- W1855444725
- Cited by
- 61
- References
- 41
- Citations by year
- 2026: 1 · 2025: 2 · 2024: 10 · 2023: 3 · 2022: 6 · 2021: 6 · 2020: 6 · 2019: 4 · 2018: 4 · 2017: 8 · 2016: 5 · 2015: 6
- FWCI
- 9.52
- Type
- journal article
- Language
- en
- Open access
- Licence
- Locations
- Autism Research (publishedVersion)
- PubMed (publishedVersion)
- Bristol Research (University of Bristol) (publishedVersion)
- Research Bank (Australian Catholic University) (submittedVersion)
- UCL Discovery (University College London) (submittedVersion)
- Research Portal (King's College London) (submittedVersion)
- The University of Bath Online Publications Store (The University of Bath) (submittedVersion)
- Pure (University of Bath) (submittedVersion, other-oa)
- Explore Bristol Research (submittedVersion)
- Funders
- Medical Research Council (G0400061/69344)
- Topics
- Social Sciences › Psychology › Clinical Psychology › Obsessive-Compulsive Spectrum Disorders
- Life Sciences › Neuroscience › Cognitive Neuroscience › Autism Spectrum Disorder Research
- Social Sciences › Psychology › Clinical Psychology › Psychoanalysis and Psychopathology Research
- Keywords
- obsessive-compulsive disorder, autism spectrum disorder, high-functioning autism, adults, Obsessive-Compulsive Inventory-Revised, self-report screening, comorbidities, repetitive behavior, psychometric properties, diagnostic thresholds
- MeSH terms
- Autism Spectrum Disorder, Adult, Female, Humans, Male, Obsessive-Compulsive Disorder, Psychiatric Status Rating Scales, Psychometrics, Surveys and Questionnaires, Severity of Illness Index, Reproducibility of Results, Self Report
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