CoChat
Sign Up
Cited by 29

The DOI matches its Crossref record; 10 of the 10 references it cites were found in a registry or an index.

p53 in the game of transposons

Wylie, Annika, Jones, Amanda E., Abrams, John M.·2016·BioEssays
DOI 10.1002/bies.201600115PMC PMC5142446
Open this paper in CoChat — free account

Abstract

Throughout the animal kingdom, p53 genes function to restrain mobile elements and recent observations indicate that transposons become derepressed in human cancers. Together, these emerging lines of evidence suggest that cancers driven by p53 mutations could represent “transpospoathies,” i.e. disease states linked to eruptions of mobile elements. The transposopathy hypothesis predicts that p53 acts through conserved mechanisms to contain transposon movement, and in this way, prevents tumor formation. How transposon eruptions provoke neoplasias is not well understood but, from a broader perspective, this hypothesis also provides an attractive framework to explore unrestrained mobile elements as inciters of late‐onset idiopathic disease. Also see the video abstract here.

Overview

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Integrity signals

Registry

Crossref · 10.1002/bies.201600115

Cites

10 of 10 references verified0 citation errors · 0 not checkable

Statistics

Verification

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Citations

Cites

Research works printed but not linked: 53

  1. 10.1101/gad.266098.115 · DOI
  2. 10.1016/j.celrep.2013.04.012 · DOI
  3. 10.1016/j.cell.2012.04.026 · DOI · Paper page
  4. 10.1002/jcb.240450108 · DOI
  5. 10.1016/j.bbrc.2005.03.190 · DOI
  6. 10.1038/35106009 · DOI · Paper page
  7. 10.1101/gad.190678.112 · DOI
  8. 10.1016/j.cell.2011.12.017 · DOI · Paper page
  9. 10.1016/S0092-8674(04)01252-8 · DOI
  10. 10.1016/j.cell.2004.11.006 · DOI · Paper page
  11. 10.1038/cdd.2013.17 · DOI
  12. 10.1038/nrm2147 · DOI
  13. 10.1038/sj.cdd.4401922 · DOI
  14. 10.1101/cshperspect.a001198 · DOI
  15. 10.1016/j.febslet.2004.03.122 · DOI
  16. 10.1074/jbc.M112.417980 · DOI
  17. 10.1038/sj.cdd.4401922 · DOI
  18. 10.1126/science.1065486 · DOI
  19. 10.1016/S0092-8674(00)80627-3 · DOI
  20. 10.1073/pnas.97.13.7301 · DOI
  21. 10.1016/S0092-8674(00)80626-1 · DOI
  22. D'Brot A, 2016, A platform for interrogating cancer‐associated p53 alleles, Oncogene, 48, 1
  23. 10.1073/pnas.172382899 · DOI
  24. 10.1126/science.1185640 · DOI
  25. 10.1038/sj.onc.1202951 · DOI
  26. 10.7554/eLife.01530 · DOI
  27. 10.1038/sj.onc.1210328 · DOI
  28. 10.1128/MCB.24.3.1219-1231.2004 · DOI
  29. Brodsky MH, 2000, mus304 encodes a novel DMA damage checkpoint protein required during Drosophila development, Genes Dev, 14, 666, 10.1101/gad.14.6.666 · DOI
  30. 10.1101/gad.1047003 · DOI
  31. 10.1083/jcb.201006034 · DOI
  32. 10.1073/pnas.1216922110 · DOI
  33. 10.1007/s11373-006-9126-2 · DOI
  34. 10.1002/bies.201600031 · DOI
  35. 10.1073/pnas.1216922110 · DOI
  36. 10.4161/mge.26693 · DOI
  37. 10.1126/science.1251343 · DOI · Paper page
  38. 10.1002/rmv.622 · DOI · Paper page
  39. 10.1016/j.autrev.2010.07.012 · DOI · Paper page
  40. 10.1016/j.gde.2012.02.006 · DOI · Paper page
  41. 10.4049/jimmunol.1302972 · DOI
  42. 10.1007/s00018-008-8496-1 · DOI · Paper page
  43. 10.1038/ni.2872 · DOI · Paper page
  44. 10.1002/dvg.20306 · DOI
  45. 10.1016/j.molcel.2007.07.012 · DOI
  46. 10.1038/onc.2009.246 · DOI
  47. 10.1038/nature12987 · DOI
  48. 10.1101/gad.1968110 · DOI
  49. 10.1128/MCB.24.15.6719-6727.2004 · DOI
  50. 10.1016/j.cell.2008.06.032 · DOI · Paper page
  51. 10.1016/j.immuni.2005.12.003 · DOI
  52. 10.1016/j.cell.2007.10.017 · DOI
  53. 10.1097/CCO.0b013e32835b6386 · DOI

Cited by

Sorted by citations

See all 29

Metadata

Authors
Wylie, A., Jones, A. E., & Abrams, J. M.
Venue
BioEssays
Publisher
Wiley
Published
2016-09-19
Volume
38
Issue
11
Pages
1111-1116
ISSN
  • 0265-9247
  • 1521-1878
DOI
10.1002/bies.201600115
PMC
PMC5142446
Cited by
29
References
10
Language
en
Licence
onlinelibrary.wiley.com/termsAndConditions#vor (vor)
Funders
  • American Cancer Society (128847‐PF‐15‐160‐01‐DDC)
  • Welch Foundation (I‐1865)

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review