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Cited by 1,317

The DOI matches its Crossref record; 6 of the 6 references it cites were found in a registry or an index.

The structure and synthesis of the fungal cell wall

Bowman, Shaun M., Free, Stephen J.·2006·BioEssays

Abstract

The fungal cell wall is a dynamic structure that protects the cell from changes in osmotic pressure and other environmental stresses, while allowing the fungal cell to interact with its environment. The structure and biosynthesis of a fungal cell wall is unique to the fungi, and is therefore an excellent target for the development of anti‐fungal drugs. The structure of the fungal cell wall and the drugs that target its biosynthesis are reviewed. Based on studies in a number of fungi, the cell wall has been shown to be primarily composed of chitin, glucans, mannans and glycoproteins. The biosynthesis of the various components of the fungal cell wall and the importance of the components in the formation of a functional cell wall, as revealed through mutational analyses, are discussed. There is strong evidence that the chitin, glucans and glycoproteins are covalently cross‐linked together and that the cross‐linking is a dynamic process that occurs extracellularly. BioEssays 28: 799–808, 2006. © 2006 Wiley Periodicals, Inc.

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Metadata

Authors
Bowman, S. M., & Free, S. J.
Venue
BioEssays
Publisher
Wiley
Published
2006-08
Volume
28
Issue
8
Pages
799-808
ISSN
  • 0265-9247 (ISSN-L)
  • 1521-1878
OpenAlex
W2006475796
Cited by
1,317
References
6
FWCI
1.09
Type
journal article
Language
en
Open access
closed

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

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