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Neuroinflammation, Microglia and Mast Cells in the Pathophysiology of Neurocognitive Disorders: A Review

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N-acylethanolamines, anandamide and food intake

Hansen, H. S., & Diep, T. A. (2009) · Biochemical Pharmacology · doi:10.1016/j.bcp.2009.04.024 · Cited by 165 · see citing works

N-acylethanolamine metabolism with special reference to N-acylethanolamine-hydrolyzing acid amidase (NAAA)

Ueda, N., Tsuboi, K., & Uyama, T. (2010) · Progress in Lipid Research · doi:10.1016/j.plipres.2010.02.003 · Cited by 164 · see citing works

From Surface to Nuclear Receptors: The Endocannabinoid Family Extends its Assets

Pistis, M., & Melis, M. (2010) · Current Medicinal Chemistry · doi:10.2174/092986710790980014 · Cited by 142 · see citing works

Human Pompe disease-induced pluripotent stem cells for pathogenesis modeling, drug testing and disease marker identification.

Huang, H.-P., Chen, P.-H., Hwu, W., Chuang, C.-Y., Chien, Y.-H., Stone, L., Chien, C.-L., Li, L.-T., Chiang, S.-C., Chen, H.-F., et al. (2011) · Human Molecular Genetics · doi:10.1093/hmg/ddr424 · Cited by 145 · see citing works

Palmitoylethanolamide and other anandamide congeners. Proposed role in the diseased brain

Hansen, H. S. (2010) · Experimental Neurology · doi:10.1016/j.expneurol.2010.03.022 · Cited by 136 · see citing works

Central administration of palmitoylethanolamide reduces hyperalgesia in mice via inhibition of NF-κB nuclear signalling in dorsal root ganglia

D’Agostino, G., Rana, G. L., Russo, R., Sasso, O., Iacono, A., Esposito, E., Raso, G. M., Cuzzocrea, S., LoVerme, J., Piomelli, D., et al. (2009) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2009.04.022 · Cited by 134 · see citing works

Biosynthesis, degradation and pharmacological importance of the fatty acid amides

Farrell, E. K., & Merkler, D. J. (2008) · Drug Discovery Today · doi:10.1016/j.drudis.2008.02.006 · Cited by 125 · see citing works

Inhibition of fatty acid amide hydrolase and cyclooxygenase-2 increases levels of endocannabinoid related molecules and produces analgesia via peroxisome proliferator-activated receptor-alpha in a model of inflammatory pain

Jhaveri, M. D., Richardson, D. S., Robinson, I., Garle, M. J., Patel, A., Sun, Y., Sagar, D. R., Bennett, A. J., Alexander, S. P. H., Kendall, D. A., et al. (2008) · Neuropharmacology · doi:10.1016/j.neuropharm.2008.04.018 · Cited by 122 · see citing works

Enzymatic machinery for endocannabinoid biosynthesis associated with calcium stores in glutamatergic axon terminals

Nyilas, R., Dudok, B., Urbán, G. M., Mackie, K., Watanabe, M., Cravatt, B. F., Freund, T. F., & Katona, I. (2008) · The Journal of Neuroscience · doi:10.1523/jneurosci.5102-07.2008 · Cited by 119 · see citing works

Therapeutic Potential of Fatty Acid Amide Hydrolase, Monoacylglycerol Lipase, and N-Acylethanolamine Acid Amidase Inhibitors

Tuo, W., Leleu‐Chavain, N., Spencer, J., Sansook, S., Millet, R., & Chavatte, P. (2016) · Journal of Medicinal Chemistry · doi:10.1021/acs.jmedchem.6b00538 · Cited by 114 · see citing works

Enzymological studies on the biosynthesis of N-acylethanolamines

Ueda, N., Tsuboi, K., & Uyama, T. (2010) · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids · doi:10.1016/j.bbalip.2010.08.010 · Cited by 112 · see citing works

N-Docosahexaenoylethanolamine: A neurotrophic and neuroprotective metabolite of docosahexaenoic acid

Kim, H., & Spector, A. A. (2018) · Molecular Aspects of Medicine · doi:10.1016/j.mam.2018.03.004 · Cited by 112 · see citing works

Palmitoylethanolamide, a naturally occurring disease-modifying agent in neuropathic pain

Skaper, S. D., Facci, L., Fusco, M., della Valle, M. F., Zusso, M., Costa, B., & Giusti, P. (2013) · Inflammopharmacology · doi:10.1007/s10787-013-0191-7 · Cited by 107 · see citing works

Enhanced endocannabinoid tone as a potential target of pharmacotherapy

Toczek, M., & Malinowska, B. (2018) · Life Sciences · doi:10.1016/j.lfs.2018.04.054 · Cited by 104 · see citing works

The endocannabinoid system and migraine

Greco, R., Gasperi, V., Maccarrone, M., & Tassorelli, C. (2010) · Experimental Neurology · doi:10.1016/j.expneurol.2010.03.029 · Cited by 100 · see citing works

An Update of Palmitoylethanolamide and Luteolin Effects in Preclinical and Clinical Studies of Neuroinflammatory Events

Cordaro, M., Cuzzocrea, S., & Crupi, R. (2020) · Antioxidants · doi:10.3390/antiox9030216 · Cited by 98 · see citing works

Enhancement of endocannabinoid signaling by fatty acid amide hydrolase inhibition: A neuroprotective therapeutic modality

Hwang, J., Adamson, C. L., Butler, D., Janero, D. R., Makriyannis, A., & Bahr, B. A. (2009) · Life Sciences · doi:10.1016/j.lfs.2009.06.003 · Cited by 97 · see citing works

Dynamic Regulation of the Endocannabinoid System: Implications for Analgesia

Sagar, D. R., Gaw, A. G., Okine, B. N., Woodhams, S. G., Wong, A., Kendall, D. A., & Chapman, V. (2009) · Molecular Pain · doi:10.1186/1744-8069-5-59 · Cited by 96 · see citing works

Cannabinoids and omega-3/6 endocannabinoids as cell death and anticancer modulators

Brown, I. M., Cascio, M. G., Rotondo, D., Pertwee, R. G., Heys, S. D., & Wahle, K. W. J. (2012) · Progress in Lipid Research · doi:10.1016/j.plipres.2012.10.001 · Cited by 94 · see citing works

Inhibition of fatty acid amide hydrolase produces PPAR‐α‐mediated analgesia in a rat model of inflammatory pain

Sagar, D. R., Kendall, D. A., & Chapman, V. (2008) · British Journal of Pharmacology · doi:10.1038/bjp.2008.335 · Cited by 88 · see citing works

Palmitoylethanolamide normalizes intestinal motility in a model of post‐inflammatory accelerated transit: involvement of CB 1 receptors and TRPV 1 channels

Capasso, R., Orlando, P., Pagano, E., Aveta, T., Buono, L., Borrelli, F., Marzo, V. D., & Izzo, A. A. (2014) · British Journal of Pharmacology · doi:10.1111/bph.12759 · Cited by 85 · see citing works

Primary fatty amides in plasma associated with brain amyloid burden, hippocampal volume, and memory in the European Medical Information Framework for Alzheimer's Disease biomarker discovery cohort

Kim, M. G., Snowden, S. G., Suvitaival, T., Ali, A., Merkler, D. J., Ahmad, T., Westwood, S., Baird, A. L., Proitsi, P., Nevado‐Holgado, A. J., et al. (2019) · Alzheimer s & Dementia · doi:10.1016/j.jalz.2019.03.004 · Cited by 84 · see citing works

Proinflammatory Stimuli Control N-Acylphosphatidylethanolamine-Specific Phospholipase D Expression in Macrophages

Zhu, C., Solorzano, C., Sahar, S., Realini, N., Fung, E. S., Sassone‐Corsi, P., & Piomelli, D. (2011) · Molecular Pharmacology · doi:10.1124/mol.110.070201 · Cited by 84 · see citing works

Chapter 5 The Endocannabinoid System as A Target for Novel Anxiolytic and Antidepressant Drugs

Gaetani, S., Dipasquale, P., Romano, A., Righetti, L., Cassano, T., Piomelli, D., & Cuomo, V. (2009) · International Review of Neurobiology · doi:10.1016/s0074-7742(09)85005-8 · Cited by 83 · see citing works

A Catalytic Mechanism for Cysteine N-Terminal Nucleophile Hydrolases, as Revealed by Free Energy Simulations

Lodola, A., Branduardi, D., Vivo, M. D., Capoferri, L., Mor, M., Piomelli, D., & Cavalli, A. (2012) · PLoS ONE · doi:10.1371/journal.pone.0032397 · Cited by 81 · see citing works

Comparative analysis of DNA methylome and transcriptome of skeletal muscle in lean-, obese-, and mini-type pigs

Yang, Y., Liang, G., Niu, G., Zhang, Y., Zhou, R., Wang, Y., Mu, Y., Tang, Z., & Li, K. (2017) · Scientific Reports · doi:10.1038/srep39883 · Cited by 71 · see citing works

Oligodendrocyte precursor cells as a therapeutic target for demyelinating diseases

Skaper, S. D. (2019) · Progress in brain research · doi:10.1016/bs.pbr.2019.03.013 · Cited by 70 · see citing works

The Impact of the CB2 Cannabinoid Receptor in Inflammatory Diseases: An Update

Rakotoarivelo, V., Mayer, T. Z., Simard, M., Flamand, N., & Marzo, V. D. (2024) · Molecules · doi:10.3390/molecules29143381 · Cited by 69 · see citing works

Alkyne lipids as substrates for click chemistry-based in vitro enzymatic assays

Gaebler, A., Milan, R., Straub, L. G., Hoelper, D., Kuerschner, L., & Thiele, C. (2013) · Journal of Lipid Research · doi:10.1194/jlr.d038653 · Cited by 69 · see citing works

Anti‐inflammatory Effect of Palmitoylethanolamide on Human Adipocytes

Hoareau, L., Buyse, M., Festy, F., Ravanan, P., Gonthier, M., Matias, I., Petrosino, S., Tallet, F., d’Hellencourt, C. L., Césari, M., et al. (2009) · Obesity · doi:10.1038/oby.2008.591 · Cited by 68 · see citing works

N-Palmitoylethanolamide-Oxazoline Protects against Middle Cerebral Artery Occlusion Injury in Diabetic Rats by Regulating the SIRT1 Pathway

Fusco, R., Scuto, M. C., Cordaro, M., D’Amico, R., Gugliandolo, E., Siracusa, R., Peritore, A. F., Crupi, R., Impellizzeri, D., Cuzzocrea, S., et al. (2019) · International Journal of Molecular Sciences · doi:10.3390/ijms20194845 · Cited by 66 · see citing works

Effect of PEA-OXA on neuropathic pain and functional recovery after sciatic nerve crush

Gugliandolo, E., D’Amico, R., Cordaro, M., Fusco, R., Siracusa, R., Crupi, R., Impellizzeri, D., Cuzzocrea, S., & Paola, R. D. (2018) · Journal of Neuroinflammation · doi:10.1186/s12974-018-1303-5 · Cited by 62 · see citing works

2-Pentadecyl-2-Oxazoline, the Oxazoline of Pea, Modulates Carrageenan-Induced Acute Inflammation

Petrosino, S., Campolo, M., Impellizzeri, D., Paterniti, I., Allarà, M., Gugliandolo, E., D’Amico, R., Siracusa, R., Cordaro, M., Esposito, E., et al. (2017) · Frontiers in Pharmacology · doi:10.3389/fphar.2017.00308 · Cited by 61 · see citing works

Chapter 1 Enzymatic Formation of Anandamide

Okamoto, Y., Tsuboi, K., & Ueda, N. (2009) · Vitamins and hormones · doi:10.1016/s0083-6729(09)81001-7 · Cited by 60 · see citing works

Role of anorectic N-acylethanolamines in intestinal physiology and satiety control with respect to dietary fat

Hansen, H. S. (2014) · Pharmacological Research · doi:10.1016/j.phrs.2014.03.006 · Cited by 60 · see citing works

Advances in the discovery of N-acylethanolamine acid amidase inhibitors

Bandiera, T., Ponzano, S., & Piomelli, D. (2014) · Pharmacological Research · doi:10.1016/j.phrs.2014.04.011 · Cited by 60 · see citing works

Fatty Acid Binding Protein‐1 (FABP1) and the Human FABP1 T94A Variant: Roles in the Endocannabinoid System and Dyslipidemias

Schroeder, F., McIntosh, A. L., Martin, G. G., Huang, H., Landrock, D., Chung, S., Landrock, K. K., Dangott, L. J., Li, S., Kaczocha, M., et al. (2016) · Lipids · doi:10.1007/s11745-016-4155-8 · Cited by 60 · see citing works

Complex Control of GABA(A) Receptor Subunit mRNA Expression: Variation, Covariation, and Genetic Regulation

Mulligan, M. K., Wang, X., Adler, A. L., Mozhui, K., Lu, L., & Williams, R. W. (2012) · PLoS ONE · doi:10.1371/journal.pone.0034586 · Cited by 59 · see citing works

Synthesis and Structure−Activity Relationships of N-(2-Oxo-3-oxetanyl)amides as N-Acylethanolamine-hydrolyzing Acid Amidase Inhibitors

Solorzano, C., Antonietti, F., Duranti, A., Tontini, A., Rivara, S., Lodola, A., Vacondio, F., Tarzia, G., Piomelli, D., & Mor, M. (2010) · Journal of Medicinal Chemistry · doi:10.1021/jm100582w · Cited by 54 · see citing works

The N-Acylethanolamine Acid Amidase Inhibitor ARN077 Suppresses Inflammation and Pruritus in a Mouse Model of Allergic Dermatitis

Sasso, O., Summa, M., Armirotti, A., Pontis, S., Mei, C. D., & Piomelli, D. (2017) · Journal of Investigative Dermatology · doi:10.1016/j.jid.2017.07.853 · Cited by 53 · see citing works

Fatty acid amide lipid mediators in plants

Kim, S., Chapman, K. D., & Blancaflor, E. B. (2010) · Plant Science · doi:10.1016/j.plantsci.2010.02.017 · Cited by 53 · see citing works

N-acylethanolamine hydrolyzing acid amidase inhibition: tools and potential therapeutic opportunities

Bottemanne, P., Muccioli, G. G., & Alhouayek, M. (2018) · Drug Discovery Today · doi:10.1016/j.drudis.2018.03.007 · Cited by 51 · see citing works

Role of the Endocannabinoid System in the Adipose Tissue with Focus on Energy Metabolism

Rakotoarivelo, V., Sihag, J., & Flamand, N. (2021) · Cells · doi:10.3390/cells10061279 · Cited by 51 · see citing works

Design and Synthesis of Potent N-Acylethanolamine-hydrolyzing Acid Amidase (NAAA) Inhibitor as Anti-Inflammatory Compounds

Li, Y., Yang, L., Chen, L., Zhu, C., Huang, R., Zheng, X., Qiu, Y., & Fu, J. X. (2012) · PLoS ONE · doi:10.1371/journal.pone.0043023 · Cited by 50 · see citing works

Inhibitors of the Endocannabinoid-Degrading Enzymes, or how to Increase Endocannabinoids Activity by Preventing their Hydrolysis

Feledziak, M., Lambert, D. M., Marchand‐Brynaert, J., & Muccioli, G. G. (2011) · Recent Patents on CNS Drug Discovery · doi:10.2174/157488912798842223 · Cited by 50 · see citing works

Palmitoylethanolamide protects mice against 6-OHDA-induced neurotoxicity and endoplasmic reticulum stress: In vivo and in vitro evidence

Avagliano, C., Russo, R., Caro, C. D., Cristiano, C., Rana, G. L., Piegari, G., Paciello, O., Citraro, R., Russo, E., Sarro, G. D., et al. (2016) · Pharmacological Research · doi:10.1016/j.phrs.2016.09.004 · Cited by 50 · see citing works

N-(2-Oxo-3-oxetanyl)carbamic Acid Esters as N-Acylethanolamine Acid Amidase Inhibitors: Synthesis and Structure–Activity and Structure–Property Relationships

Duranti, A., Tontini, A., Antonietti, F., Vacondio, F., Fioni, A., Silva, C., Lodola, A., Rivara, S., Solorzano, C., Piomelli, D., et al. (2012) · Journal of Medicinal Chemistry · doi:10.1021/jm300349j · Cited by 48 · see citing works

Lack of association of genetic variants in genes of the endocannabinoid system with anorexia nervosa

Müller, T. D., Reichwald, K., Brönner, G., Kirschner, J., Nguyen, T. T., Scherag, A., Herzog, W., Herpertz‐Dahlmann, B., Lichtner, P., Meitinger, T., et al. (2008) · Child and Adolescent Psychiatry and Mental Health · doi:10.1186/1753-2000-2-33 · Cited by 48 · see citing works

Synthesis and Structure–Activity Relationship (SAR) of 2-Methyl-4-oxo-3-oxetanylcarbamic Acid Esters, a Class of Potent N-Acylethanolamine Acid Amidase (NAAA) Inhibitors

Ponzano, S., Bertozzi, F., Mengatto, L., Dionisi, M., Armirotti, A., Romeo, E., Berteotti, A., Fiorelli, C., Tarozzo, G., Reggiani, A. M., et al. (2013) · Journal of Medicinal Chemistry · doi:10.1021/jm400739u · Cited by 47 · see citing works

Second‐Generation Non‐Covalent NAAA Inhibitors are Protective in a Model of Multiple Sclerosis

Migliore, M., Pontis, S., de Arriba, A. L. F., Realini, N., Torrente, E., Armirotti, A., Romeo, E., Martino, S. D., Russo, D., Pizzirani, D., et al. (2016) · Angewandte Chemie International Edition · doi:10.1002/anie.201603746 · Cited by 47 · see citing works

Potential analgesic effects of a novel N-acylethanolamine acid amidase inhibitor F96 through PPAR-α

Yang, L., Li, L., Chen, L., Li, Y., Chen, H., Li, Y., Ji, G., Lin, D., Liu, Z., & Qiu, Y. (2015) · Scientific Reports · doi:10.1038/srep13565 · Cited by 46 · see citing works

The endocannabinoid system and related lipids as potential targets for the treatment of migraine‐related pain

Greco, R., Demartini, C., Zanaboni, A. M., Francavilla, M., Icco, R. D., Ahmad, L., & Tassorelli, C. (2022) · Headache The Journal of Head and Face Pain · doi:10.1111/head.14267 · Cited by 45 · see citing works

Molecular mechanism of activation of the immunoregulatory amidase NAAA

Gorelik, A., Gebai, A., Illes, K., Piomelli, D., & Nagar, B. (2018) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1811759115 · Cited by 45 · see citing works

Shifting Paradigms in Allergic Contact Dermatitis: The Role of Innate Immunity

Brys, A. K., Rodriguez-Homs, L. G., Suwanpradid, J., Atwater, A. R., & MacLeod, A. S. (2019) · Journal of Investigative Dermatology · doi:10.1016/j.jid.2019.03.1133 · Cited by 44 · see citing works

Expression and Secretion of N-acylethanolamine-hydrolysing Acid Amidase in Human Prostate Cancer Cells

Wang, J., Zhao, L.-Y., Uyama, T., Tsuboi, K., Wu, X., Kakehi, Y., & Ueda, N. (2008) · The Journal of Biochemistry · doi:10.1093/jb/mvn122 · Cited by 44 · see citing works

Beneficial Effects of Palmitoylethanolamide on Expressive Language, Cognition, and Behaviors in Autism: A Report of Two Cases

Antonucci, N., Cirillo, A., & Siniscalco, D. (2015) · Case Reports in Psychiatry · doi:10.1155/2015/325061 · Cited by 44 · see citing works

Proteome Alterations in Primary Human Alveolar Macrophages in Response to Influenza A Virus Infection

Liu, L., Zhou, J., Wang, Y., Mason, R. J., Funk, C. J., & Du, Y. (2012) · Journal of Proteome Research · doi:10.1021/pr3001332 · Cited by 43 · see citing works

Phyto-, endo- and synthetic cannabinoids: promising chemotherapeutic agents in the treatment of breast and prostate carcinomas

Fraguas‐Sánchez, A. I., Fernández-Carballido, A. M., & Torres‐Suárez, A. I. (2016) · Expert Opinion on Investigational Drugs · doi:10.1080/13543784.2016.1236913 · Cited by 43 · see citing works

The role of ethanolamine phosphate phospholyase in regulation of astrocyte lipid homeostasis

White, C. J., Ellis, J. M., & Wolfgang, M. J. (2021) · Journal of Biological Chemistry · doi:10.1016/j.jbc.2021.100830 · Cited by 42 · see citing works

CD36 gene deletion decreases oleoylethanolamide levels in small intestine of free-feeding mice

Guijarro, A. I., Fu, J., Astarita, G., & Piomelli, D. (2009) · Pharmacological Research · doi:10.1016/j.phrs.2009.09.003 · Cited by 42 · see citing works

Lipophilic amines as potent inhibitors of N-acylethanolamine-hydrolyzing acid amidase

Yamano, Y., Tsuboi, K., Hozaki, Y., Takahashi, K., Jin, X., Ueda, N., & Wada, A. (2012) · Bioorganic & Medicinal Chemistry · doi:10.1016/j.bmc.2012.03.065 · Cited by 41 · see citing works

A proposed modulatory role of the endocannabinoid system on adipose tissue metabolism and appetite in periparturient dairy cows

Myers, M. N., Zachut, M., Tam, J., & Contreras, G. A. (2021) · Journal of Animal Science and Biotechnology/Journal of animal science and biotechnology · doi:10.1186/s40104-021-00549-3 · Cited by 40 · see citing works

Biochemical and Mass Spectrometric Characterization of Human N-Acylethanolamine-Hydrolyzing Acid Amidase Inhibition

West, J. M., Zvonok, N., Whitten, K. M., Vadivel, S. K., Bowman, A. L., & Makriyannis, A. (2012) · PLoS ONE · doi:10.1371/journal.pone.0043877 · Cited by 39 · see citing works

Palmitoylethanolamide, a neutraceutical, in nerve compression syndromes: efficacy and safety in sciatic pain and carpal tunnel syndrome

Hesselink, J. M. K., & Kopsky, D. J. (2015) · Journal of Pain Research · doi:10.2147/jpr.s93106 · Cited by 38 · see citing works

β-Lactams Derived from a Carbapenem Chiron Are Selective Inhibitors of Human Fatty Acid Amide Hydrolase versus Human Monoacylglycerol Lipase

Feledziak, M., Michaux, C., Urbach, A., Labar, G., Muccioli, G. G., Lambert, D. M., & Marchand‐Brynaert, J. (2009) · Journal of Medicinal Chemistry · doi:10.1021/jm9008532 · Cited by 38 · see citing works

β-Lactones Inhibit N-acylethanolamine Acid Amidase by S-Acylation of the Catalytic N-Terminal Cysteine

Armirotti, A., Romeo, E., Ponzano, S., Mengatto, L., Dionisi, M., Karacsonyi, C., Bertozzi, F., Garau, G., Tarozzo, G., Reggiani, A. M., et al. (2012) · ACS Medicinal Chemistry Letters · doi:10.1021/ml300056y · Cited by 37 · see citing works

Mediterranean Diet and Neurodegenerative Diseases: The Neglected Role of Nutrition in the Modulation of the Endocannabinoid System

Armeli, F., Bonucci, A., Maggi, E., Pinto, A., & Businaro, R. (2021) · Biomolecules · doi:10.3390/biom11060790 · Cited by 36 · see citing works

FAAH-mediated modulation of TLR3-induced neuroinflammation in the rat hippocampus

Henry, R. J., Kerr, D. M., Finn, D. P., & Roche, M. (2014) · Journal of Neuroimmunology · doi:10.1016/j.jneuroim.2014.09.002 · Cited by 36 · see citing works

New factors for protein transport identified by a genome-wide CRISPRi screen in mammalian cells

Bassaganyas, L., Popa, S. J., Horlbeck, M. A., Puri, C., Stewart, S. E., Campelo, F., Ashok, A., Butnaru, C. M., Brouwers, N., Heydari, K., et al. (2019) · The Journal of Cell Biology · doi:10.1083/jcb.201902028 · Cited by 35 · see citing works

PEA-OXA Mitigates Oxaliplatin-Induced Painful Neuropathy through NF-κB/Nrf-2 Axis

Campolo, M., Lanza, M., Paterniti, I., Filippone, A., Ardizzone, A., Casili, G., Scuderi, S. A., Puglisi, C., Mare, M., Memeo, L., et al. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22083927 · Cited by 35 · see citing works

Ulcerative Colitis Impairs the Acylethanolamide-Based Anti-Inflammatory System Reversal by 5-Aminosalicylic Acid and Glucocorticoids

Suárez, J., Romero‐Zerbo, S., Márquez, L., Rivera, P., Iglesias, M., Bermúdez‐Silva, F. J., Andreu, M. G., & de Fonseca, F. R. (2012) · PLoS ONE · doi:10.1371/journal.pone.0037729 · Cited by 35 · see citing works

N-Acylethanolamine acid amidase (NAAA) inhibitor F215 as a novel therapeutic agent for osteoarthritis.

Zhou, P., Xiang, L., Yang, Y.-L., Wu, Y., Hu, T., Liu, X.-L., Lin, F.-T., Xiu, Y., Wu, K., Lu, C.-Z., et al. (2019) · Pharmacological Research · doi:10.1016/j.phrs.2019.104264 · Cited by 32 · see citing works

Synthesis, Structure–Activity, and Structure–Stability Relationships of 2‐Substituted‐N‐(4‐oxo‐3‐oxetanyl) N‐Acylethanolamine Acid Amidase (NAAA) Inhibitors

Vitale, R., Ottonello, G., Petracca, R., Bertozzi, S. M., Ponzano, S., Armirotti, A., Berteotti, A., Dionisi, M., Cavalli, A., Piomelli, D., et al. (2014) · ChemMedChem · doi:10.1002/cmdc.201300416 · Cited by 29 · see citing works

3‐Aminoazetidin‐2‐one Derivatives as N‐Acylethanolamine Acid Amidase (NAAA) Inhibitors Suitable for Systemic Administration

Fiasella, A., Nuzzi, A., Summa, M., Armirotti, A., Tarozzo, G., Tarzia, G., Mor, M., Bertozzi, F., Bandiera, T., & Piomelli, D. (2014) · ChemMedChem · doi:10.1002/cmdc.201300546 · Cited by 28 · see citing works

Potent α-amino-β-lactam carbamic acid ester as NAAA inhibitors. Synthesis and structure–activity relationship (SAR) studies

Nuzzi, A., Fiasella, A., Ortega, J. A., Pagliuca, C., Ponzano, S., Pizzirani, D., Bertozzi, S. M., Ottonello, G., Tarozzo, G., Reggiani, A. M., et al. (2016) · European Journal of Medicinal Chemistry · doi:10.1016/j.ejmech.2016.01.046 · Cited by 28 · see citing works

Activity-Based Probe for N-Acylethanolamine Acid Amidase

Romeo, E., Ponzano, S., Armirotti, A., Summa, M., Bertozzi, F., Garau, G., Bandiera, T., & Piomelli, D. (2015) · ACS Chemical Biology · doi:10.1021/acschembio.5b00197 · Cited by 27 · see citing works

Inhibition of N-acylethanolamine acid amidase reduces nicotine-induced dopamine activation and reward

Sagheddu, C., Scherma, M., Congiu, M., Fadda, P., Carta, G., Banni, S., Wood, J. T., Makriyannis, A., Malamas, M. S., & Pistis, M. (2018) · Neuropharmacology · doi:10.1016/j.neuropharm.2018.11.013 · Cited by 27 · see citing works

Palmitoylethanolamide stimulates phagocytosis of Escherichia coli K1 and Streptococcus pneumoniae R6 by microglial cells

Redlich, S., Ribes, S., Schütze, S., Czesnik, D., & Nau, R. (2012) · Journal of Neuroimmunology · doi:10.1016/j.jneuroim.2011.12.013 · Cited by 26 · see citing works

Behavioral Neurobiology of the Endocannabinoid System

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Joint Synovial Fluid Metabolomics Method to Decipher the Metabolic Mechanisms of Adjuvant Arthritis and Geniposide Intervention

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