Childhood trauma and suicide attempts in patients with unipolar depression
Open accessAbstract
Although general population studies have reported that childhood trauma predisposes individuals to suicidal behavior, there have been few clinical studies in depressed patients. A series of 108 patients with unipolar depression were evaluated for their suicide attempt history and completed the 34-item Childhood Trauma Questionnaire (CTQ). Patients were also interviewed with the Brown-Goodwin Lifetime History of Aggression (BGLHA) scale. Out of 108 patients with depression, 47 (43.5%) had attempted suicide. Significantly more of the depressed patients who had attempted suicide were female, single, and unemployed. Patients who had attempted suicide had significantly higher total CTQ scores and higher CTQ scores for emotional abuse and emotional neglect, as well as higher BGLHA scores. Logistic regression identified being female, being unemployed, having undergone childhood emotional neglect, and high BGLHA scores as significantly associated with making a suicide attempt. Suicidal behavior in unipolar depression appears to be a multidetermined act, with sociodemographic, developmental, and personality determinants.
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Cites
Hamilton, M. (1960) · Journal of Neurology, Neurosurgery & Psychiatry · doi:10.1136/jnnp.23.1.56 · Cited by 32,817 · see citing works
Initial reliability and validity of a new retrospective measure of child abuse and neglect
(1994) · American Journal of Psychiatry · doi:10.1176/ajp.151.8.1132 · Cited by 3,577 · see citing works
Validity of the Childhood Trauma Questionnaire in an Adolescent Psychiatric Population
BERNSTEIN, D. P., AHLUVALIA, T., POGGE, D., & HANDELSMAN, L. (1997) · Journal of the American Academy of Child & Adolescent Psychiatry · doi:10.1097/00004583-199703000-00012 · Cited by 1,574 · see citing works
Aggression in humans correlates with cerebrospinal fluid amine metabolites
Brown, G. L., Goodwin, F. K., Ballenger, J. C., Goyer, P. F., & Major, L. F. (1979) · Psychiatry Research · doi:10.1016/0165-1781(79)90053-2 · Cited by 1,133 · see citing works
Childhood Maltreatment Increases Risk for Personality Disorders During Early Adulthood
Johnson, J. G., Cohen, P., Brown, J., Smailes, E. M., & Bernstein, D. P. (1999) · Archives of General Psychiatry · doi:10.1001/archpsyc.56.7.600 · Cited by 839 · see citing works
FERGUSSON, D. M., WOODWARD, L. J., & HORWOOD, L. J. (2000) · Psychological Medicine · doi:10.1017/s003329179900135x · Cited by 832 · see citing works
Association Between Self-reported Childhood Sexual Abuse and Adverse Psychosocial Outcomes
Nelson, E. C., Heath, A. C., Madden, P. A. F., Cooper, M. L., Dinwiddie, S. H., Bucholz, K. K., Glowinski, A. L., McLaughlin, T., Dunne, M. P., Statham, D. J., et al. (2002) · Archives of General Psychiatry · doi:10.1001/archpsyc.59.2.139 · Cited by 739 · see citing works
FERGUSSON, D. M., HORWOOD, L. J., & WOODWARD, L. J. (2000) · Psychological Medicine · doi:10.1017/s0033291799002111 · Cited by 655 · see citing works
Dumais, A., Lesage, A. D., Alda, M., Rouleau, G., Dumont, M., Chawky, N., Roy, M., Mann, J. J., Benkelfat, C., & Turecki, G. (2005) · American Journal of Psychiatry · doi:10.1176/appi.ajp.162.11.2116 · Cited by 583 · see citing works
IDENTIFICATION OF SUICIDE RISK FACTORS USING EPIDEMIOLOGIC STUDIES
Mościcki, E. K. (1997) · Psychiatric Clinics of North America · doi:10.1016/s0193-953x(05)70327-0 · Cited by 507 · see citing works
Brodsky, B. S., Oquendo, M., Ellis, S. P., Haas, G. L., Malone, K. M., & Mann, J. J. (2001) · American Journal of Psychiatry · doi:10.1176/appi.ajp.158.11.1871 · Cited by 438 · see citing works
Impact of childhood abuse on the clinical course of bipolar disorder
Garno, J. L., Goldberg, J. F., RAMIREZ, P. M., & Ritzler, B. A. (2005) · The British Journal of Psychiatry · doi:10.1192/bjp.186.2.121 · Cited by 413 · see citing works
Bernstein, D. M. (1994) · American Journal of Psychiatry · doi:10.1176/ajp.151.1.18 · Cited by 408 · see citing works
Assessment and prediction of suicide
Pfeffer, C. R. (1993) · General Hospital Psychiatry · doi:10.1016/0163-8343(93)90045-p · Cited by 399 · see citing works
Molnar, B. E., Berkman, L. F., & Buka, S. L. (2001) · Psychological Medicine · doi:10.1017/s0033291701004329 · Cited by 394 · see citing works
Leverich, G. S., Altshuler, L. L., Frye, M. A., Suppes, T. M., Keck, P. E., McElroy, S. L., Denicoff, K. D., Obrocea, G. V., Nolen, W. A., Kupka, R., et al. (2003) · The Journal of Clinical Psychiatry · doi:10.4088/jcp.v64n0503 · Cited by 354 · see citing works
Goodman, L. A., Thompson, K. M., Weinfurt, K., Corl, S., Acker, P., Mueser, K. T., & Rosenberg, S. D. (1999) · Journal of Traumatic Stress · doi:10.1023/a:1024708916143 · Cited by 329 · see citing works
Major depression and the risk of attempted suicide
Malone, K. M., Haas, G. L., Sweeney, J. A., & Mann, J. J. (1995) · Journal of Affective Disorders · doi:10.1016/0165-0327(95)00015-f · Cited by 302 · see citing works
Suicidal behavior in bipolar mood disorder: clinical characteristics of attempters and nonattempters
Oquendo, M. A., WATERNAUX, C. M., Brodsky, B. S., Parsons, B., Haas, G. L., Malone, K. M., & Mann, J. J. (2000) · Journal of Affective Disorders · doi:10.1016/s0165-0327(99)00129-9 · Cited by 290 · see citing works
Memories of Childhood Neglect and Abuse: Corroboration in a Series of Sisters
Bifulco, A. T., Brown, G. W., Lillie, A., & Jarvis, J. (1997) · Journal of Child Psychology and Psychiatry · doi:10.1111/j.1469-7610.1997.tb01520.x · Cited by 251 · see citing works
The Association of Sexual Assault and Attempted Suicide Within the Community
Davidson, J. R. T. (1996) · Archives of General Psychiatry · doi:10.1001/archpsyc.1996.01830060096013 · Cited by 210 · see citing works
Childhood Sexual and Physical Abuse and Adult Self-Harm and Suicidal Behaviour: A Literature Review
Mina, E. E. S., & Gallop, R. (1998) · The Canadian Journal of Psychiatry · doi:10.1177/070674379804300803 · Cited by 190 · see citing works
Bipolar Disorder With Comorbid Cluster B Personality Disorder Features
Garno, J. L., Goldberg, J. F., RAMIREZ, P. M., & Ritzler, B. A. (2005) · The Journal of Clinical Psychiatry · doi:10.4088/jcp.v66n0310 · Cited by 114 · see citing works
Characteristics of drug addicts who attempt suicide.
Roy, A. (2003) · Psychiatry Research · doi:10.1016/s0165-1781(03)00206-3 · Cited by 109 · see citing works
Self-citationLife Events and Psychopathology in a Group of Suicide Attempters
Osváth, P., Vörös, V., & Fekete, S. (2004) · Psychopathology · doi:10.1159/000077018 · Cited by 68 · see citing works
Flagged first, then by citations
Cited by
Sorted by citations
Childhood maltreatment and adult suicidality: a comprehensive systematic review with meta-analysis
Angelakis, I., Gillespie, E. L., & Panagioti, M. (2019) · Psychological Medicine · doi:10.1017/s0033291718003823 · Cited by 479 · see citing works
“Age (years) Q.A. abuse and physical and emotional neglect Sarchiapone et al. (2007) Italy Crosssectional Childhood Trauma Questionnaire (CTQ) Childhood physical, sexual, emotional abuse and physical and emotional neglect A structured psychiatric interview Suicide attempts Patients with unipolar…”
BackgroundThombs, B. D., Bernstein, D. P., Lobbestael, J., & Arntz, A. (2009) · Child Abuse & Neglect · doi:10.1016/j.chiabu.2009.03.001 · Cited by 313 · see citing works
Roy, A., Gorodetsky, E., Yuan, Q., Goldman, D., & Enoch, M.-A. (2010) · Neuropsychopharmacology · doi:10.1038/npp.2009.236 · Cited by 282 · see citing works
Self-citationA prospective study of predictors of depression symptoms in police
Wang, Z., Inslicht, S. S., Metzler, T. J., Henn-Haase, C., McCaslin, S. E., Tong, H., Neylan, T. C., & Marmar, C. R. (2010) · Psychiatry Research · doi:10.1016/j.psychres.2008.11.010 · Cited by 182 · see citing works
Associations between suicidal behavior and childhood abuse and neglect: A meta-analysis
Liu, J., Fang, Y., Gong, J., Cui, X., Meng, T., Xiao, B., He, Y., Shen, Y., & Luo, X. (2017) · Journal of Affective Disorders · doi:10.1016/j.jad.2017.03.060 · Cited by 162 · see citing works
Boldrini, M., Galfalvy, H., Dwork, A. J., Rosoklija, G. B., Trencevska-Ivanovska, I., Pavlovski, G., Hen, R., Arango, V., & Mann, J. J. (2019) · Biological Psychiatry · doi:10.1016/j.biopsych.2018.12.022 · Cited by 116 · see citing works
Sarchiapone, M., Carli, V., Roy, A., Iacoviello, L., Cuomo, C., Latella, M. C., di Giannantonio, M., Janiri, L., de Gaetano, M., & Janal, M. N. (2008) · Neuropsychobiology · doi:10.1159/000142361 · Cited by 115 · see citing works
Self-citationGlenn, C. R., Cha, C. B., Kleiman, E. M., & Nock, M. K. (2017) · Clinical Psychological Science · doi:10.1177/2167702616686854 · Cited by 113 · see citing works
Stress, cortisol and suicide risk
(2020) · International Review of Neurobiology · doi:10.1016/bs.irn.2019.11.006 · Cited by 108 · see citing works
Role of FKBP5 in emotion processing: results on amygdala activity, connectivity and volume
Holz, N. E., Buchmann, A. F., Boecker, R., Blomeyer, D., Baumeister, S., Wolf, I., Rietschel, M., Witt, S. H., Plichta, M. M., Meyer-Lindenberg, A., et al. (2015) · Brain Structure and Function · doi:10.1007/s00429-014-0729-5 · Cited by 82 · see citing works
O'Connor, D. B., Branley-Bell, D., Green, J. A., Ferguson, E., O'Carroll, R. E., & O'Connor, R. C. (2020) · Journal of Abnormal Psychology · doi:10.1037/abn0000482 · Cited by 60 · see citing works
Baldini, V., Gottardi, C., Di Stefano, R., Rindi, L. V., Pazzocco, G., Varallo, G., Purgato, M., De Ronchi, D., Barbui, C., & Ostuzzi, G. (2025) · European Psychiatry · doi:10.1192/j.eurpsy.2025.2452 · Cited by 41 · see citing works
Blekić, W., Rossignol, M., Wauthia, E., & Felmingham, K. L. (2021) · International Journal of Psychophysiology · doi:10.1016/j.ijpsycho.2021.09.009 · Cited by 9 · see citing works
- Authors
- Sarchiapone, M., Carli, V., Cuomo, C., & Roy, A.
- Affiliations
- University of Molise (IT)
- VA New Jersey Health Care System (US)
- Venue
- Depression and Anxiety
- Publisher
- Wiley
- Published
- 2007
- Volume
- 24
- Issue
- 4
- Pages
- 268-272
- ISSN
- 1091-4269 (ISSN-L)
- 1520-6394
- OpenAlex
- W1991564170
- Cited by
- 100
- References
- 25
- Citations by year
- 2026: 3 · 2025: 5 · 2024: 5 · 2023: 5 · 2022: 5 · 2021: 12 · 2020: 3 · 2019: 7 · 2018: 6 · 2017: 4 · 2016: 2 · 2015: 8 · 2014: 8 · 2013: 6 · 2012: 2
- FWCI
- 4.42
- Type
- journal article
- Language
- en
- Open access
- green
- hdl.handle.net
- Licence
- public-domain
- doi.wiley.com/10.1002/tdm_license_1.1 (tdm, 3165 d)
- Locations
- Depression and Anxiety (publishedVersion)
- PubMed (publishedVersion)
- Archivio Istituzionale della Ricerca - Università degli Studi del Molise (submittedVersion, public-domain)
- Topics
- Social Sciences › Psychology › Clinical Psychology › Suicide and Self-Harm Studies
- Social Sciences › Psychology › Clinical Psychology › Child Abuse and Trauma
- Social Sciences › Sociology and Political Science › Homicide, Infanticide, and Child Abuse
- Keywords
- childhood trauma, suicide attempts, major depressive disorder, Childhood Trauma Questionnaire, emotional neglect, emotional abuse, sociodemographic risk factors, personality traits, suicidal behavior
- MeSH terms
- Adult, Aggression, Child, Child Abuse, Depressive Disorder, Female, Humans, Life Change Events, Male, Psychiatric Status Rating Scales, Surveys and Questionnaires, Risk Factors, Single Person, Suicide, Attempted, Unemployment, Logistic Models, Sex Distribution
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
