Associations between suicidal behavior and childhood abuse and neglect: A meta-analysis
Abstract
Background Relationships of some types of childhood maltreatment and suicidal behavior remain controversial and inconclusive.Methods Medline, Embase, PsycINFO and Cochrane library were searched for eligible studies, and the results were synthesized in meta-analyses.Results childhood maltreatment was associated positively with suicidal behavior in the total population and maltreatment subgroups. Emotional abuse had the strongest effect (OR =2.33, SMD =0.660, P<0.001). Subgroup analyses showed that the effects of childhood abuse (OR =1.55, SMD =0.523) and neglect (OR =1.25, SMD =0.31) were significant. According to the analysis of dichotomous outcomes, childhood maltreatment was associated positively with suicidal behavior in men and women (women: OR =4.84, P<0.001; men: OR =1.03, P<0.001). Among populations, childhood maltreatment had the strongest effect on suicidal behavior in the general population (OR =3.78, P<0.001). However, the analysis of continuous outcomes showed that the effect was strongest in patients with chronic schizophrenia (SMD =0.89, P<0.001). In addition, childhood maltreatment was associated positively with suicide attempt (OR =1.11, SMD =0.48, P<0.001), but not with suicidal ideation.Limitations Some subgroup samples were not sufficiently large.Conclusions Childhood maltreatment increases the risk of suicidal behavior. Emotional abuse had the strongest effect among the five types of maltreatment. The risk of suicidal behavior is higher in the general population, women, and individuals with chronic schizophrenia who have histories of childhood maltreatment.
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NSSI might often be underestimated and underreported.
“NSSI, which might often be underestimated and underreported [68, 69]”
From Association between adverse childhood experiences and suicidal behavior in affective disorders: A systematic review and meta-analysis (2025) · cites this paper as [69]
Prior meta-analyses combined studies based on mixed samples of participants such as adolescents and adults, community and clinical samples.
“These meta-analyses, however, combined studies which were based on mixed samples of participants such as adolescents and adults, community and clinical samples.”
From Childhood maltreatment and adult suicidality: a comprehensive systematic review with meta-analysis (2019) · cites this paper as Liu, et al., 2017
Two meta-analyses have confirmed the positive relationship between distinct types of childhood maltreatment and suicidality.
“To date, two meta-analyses have confirmed the positive relationship between distinct types of childhood maltreatment and suicidality (Liu, et al., 2017; Zatti, et al., 2017).”
From Childhood maltreatment and adult suicidality: a comprehensive systematic review with meta-analysis (2019) · cites this paper as Liu, et al., 2017
Methodological restrictions in prior meta-analyses regarding definition of childhood maltreatment, study design, and date of publication led to the exclusion of several relevant studies.
“On the other hand, methodological restrictions have been applied regarding the definition of childhood maltreatment (e.g. use of the Childhood Trauma Questionnaire exclusively; CTQ; Liu et al., 2017), the study design (e.g. prospective studies only) and the date of publication (conducted within the last decade; Zatti et al., 2017), leading to the exclusion of several relevant studies.”
From Childhood maltreatment and adult suicidality: a comprehensive systematic review with meta-analysis (2019) · cites this paper as Liu et al., 2017
The findings of the main analyses are generally consistent with less extensive systematic reviews in that childhood maltreatment is associated with a greater risk for suicide attempts.
“The findings of the main analyses are generally consistent with the findings of less extensive systematic reviews in that childhood maltreatment is associated with a greater risk for suicide attempts (Liu et al., 2017; Zatti et al., 2017).”
From Childhood maltreatment and adult suicidality: a comprehensive systematic review with meta-analysis (2019) · cites this paper as Liu et al., 2017
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- Authors
- Liu, J., Fang, Y., Gong, J., Cui, X., Meng, T., Xiao, B., He, Y., Shen, Y., & Luo, X.
- Affiliations
- Central South University (CN)
- Hunan University of Traditional Chinese Medicine (CN)
- Corresponding author
- Luo, Xuerong
- Venue
- Journal of Affective Disorders
- Publisher
- Elsevier BV
- Published
- 2017-10
- Volume
- 220
- Pages
- 147-155
- ISSN
- 0165-0327 (ISSN-L)
- OpenAlex
- W2601002345
- Cited by
- 162
- References
- 66
- Citations by year
- 2026: 17 · 2025: 23 · 2024: 20 · 2023: 20 · 2022: 18 · 2021: 19 · 2020: 19 · 2019: 16 · 2018: 8 · 2017: 2
- FWCI
- 1.88
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Affective Disorders (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Hunan Provincial Innovation Foundation (CX2016B062)
- Topics
- Social Sciences › Psychology › Clinical Psychology › Suicide and Self-Harm Studies
- Social Sciences › Psychology › Clinical Psychology › Child Abuse and Trauma
- Social Sciences › Sociology and Political Science › Homicide, Infanticide, and Child Abuse
- Keywords
- suicidal behavior, child abuse, childhood abuse, child neglect, emotional abuse, suicide attempts, suicidal ideation, chronic schizophrenia, sex differences, general population
- MeSH terms
- Child, Child Abuse, Female, Humans, Male, Neuropsychological Tests, Suicide, Attempted, Suicidal Ideation
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