Cited by 57Physical Activity and HealthDiabetes Management and EducationMobile Health and mHealth Applications

A systematic review of adherence to physical activity interventions in individuals with type 2 diabetes

MacDonald, Christopher S., Ried‐Larsen, Mathias, Soleimani, Jalal, Alsawas, Mouaz, Lieberman, Daniel E., Ismail, Abdalla S., Serafim, Laura P., Yang, Ting +4 more·2021·Diabetes/Metabolism Research and Reviews

Abstract

Lifestyle interventions are pivotal for successful management of type 2 diabetes (T2D), however, the proportion of people with T2D adhering to physical activity advice has not been thoroughly studied. The purpose of this systematic review was to summarise the evidence on adherence to exercise or physical activity components in lifestyle interventions in those with T2D. We searched MEDLINE EMBASE, Cochrane Central Register of Controlled Trials, Cochrane Database of Systematic Reviews and Scopus on 12 November 2019. Eligible studies enrolled adults with T2D and reported the proportion of adherence to lifestyle interventions as a primary or secondary outcome. We included 11 studies (nine randomised controlled trials (RCTs) enrolling 1717 patients and two nonrandomised studies enrolling 62 patients). Only one of the studies had low risk of bias. The proportion of participants adhering to physical activity varied from 32% to 100% with a median of 58%. Adherence was higher in interventions using supervised training and lowest in interventions using remote coaching and the adherence rate in observational studies was higher compared to RCTs (92% vs. 55%; p < 0.01). Study duration, risk of bias, or participants' sex, were not associated with adherence to physical activity. The proportion of those with T2D adhering to physical activity interventions for T2D varies widely and most of the included studies had a high risk of bias. These findings have important implications for planning and power analysis of future trials and when counselling patients about lifestyle interventions including physical activity or exercise components.

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Crossref · 10.1002/dmrr.3444

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Authors
MacDonald, C. S., Ried‐Larsen, M., Soleimani, J., Alsawas, M., Lieberman, D. E., Ismail, A. S., Serafim, L. P., Yang, T., Prokop, L., Joyner, M., Murad, M. H., & Barwise, A.
Affiliations
  • University of Copenhagen (DK)
  • Mayo Clinic (US)
  • University of Iowa (US)
  • Harvard University (US)
  • Aultman Hospital (US)
  • Universidade Federal do Rio Grande do Sul (BR)
  • West China Hospital of Sichuan University (CN)
Corresponding author
MacDonald, Christopher S.
Venue
Diabetes/Metabolism Research and Reviews
Publisher
Wiley
Published
2021-03-26
Volume
37
Issue
8
Pages
e3444-e3444
ISSN
  • 1520-7552 (ISSN-L)
  • 1520-7560
OpenAlex
W3133692570
Cited by
57
References
57
Citations by year
2026: 10 · 2025: 15 · 2024: 10 · 2023: 15 · 2022: 6 · 2021: 1
FWCI
1.07
Type
journal article
Language
en
Open access
closed
Locations
  • Diabetes/Metabolism Research and Reviews (publishedVersion)
  • PubMed (publishedVersion)
  • Research at the University of Copenhagen (University of Copenhagen) (publishedVersion)
Funders
  • National Center for Advancing Translational Sciences (UL1 TR002377)
  • TrygFonden (101390, 20045)
Topics
  • Health Sciences › Medicine › Physiology › Physical Activity and Health
  • Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Management and Education
  • Health Sciences › Health Professions › General Health Professions › Mobile Health and mHealth Applications
Keywords
type 2 diabetes, physical activity adherence, exercise adherence, lifestyle intervention, supervised exercise, remote coaching, observational studies, risk of bias, patient counseling
MeSH terms
Adult, Diabetes Mellitus, Type 2, Humans, Life Style, Exercise, Bias

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