Changing Physical Activity Behavior in Type 2 Diabetes
Open accessAbstract
OBJECTIVE: Behavioral interventions targeting “free-living” physical activity (PA) and exercise that produce long-term glycemic control in adults with type 2 diabetes are warranted. However, little is known about how clinical teams should support adults with type 2 diabetes to achieve and sustain a physically active lifestyle. RESEARCH DESIGN AND METHODS: We conducted a systematic review of randomized controlled trials (RCTs) (published up to January 2012) to establish the effect of behavioral interventions (compared with usual care) on free-living PA/exercise, HbA1c, and BMI in adults with type 2 diabetes. Study characteristics, methodological quality, practical strategies for increasing PA/exercise (taxonomy of behavior change techniques), and treatment fidelity strategies were captured using a data extraction form. RESULTS: Seventeen RCTs fulfilled the review criteria. Behavioural interventions showed statistically significant increases in objective (standardized mean difference [SMD] 0.45, 95% CI 0.21–0.68) and self-reported PA/exercise (SMD 0.79, 95% CI 0.59–0.98) including clinically significant improvements in HbA1c (weighted mean difference [WMD] –0.32%, 95% CI –0.44% to –0.21%) and BMI (WMD –1.05 kg/m2, 95% CI –1.31 to –0.80). Few studies provided details of treatment fidelity strategies to monitor/improve provider training. Intervention features (e.g., specific behavior change techniques, interventions underpinned by behavior change theories/models, and use of ≥10 behaviour change techniques) moderated effectiveness of behavioral interventions. CONCLUSIONS: Behavioral interventions increased free-living PA/exercise and produced clinically significant improvements in long-term glucose control. Future studies should consider use of theory and multiple behavior change techniques associated with clinically significant improvements in HbA1c, including structured training for care providers on the delivery of behavioural interventions.
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MI has been associated with improvements, but its effect size has only been moderate (e.g., ES for physical activity = 0.19).
“While MI has been associated with improvements, the effect size of this technique has only been moderate (e.g., ES for physical activity = 0.19) [115].”
From Positive Psychological Interventions for Patients with Type 2 Diabetes: Rationale, Theoretical Model, and Intervention Development (2015) · cites this paper as [115]
Multicomponent intervention packages have the highest efficacy for behavioral and glycemic outcomes.
“Multicomponent intervention packages have the highest efficacy for behavioral and glycemic outcomes (300,309,311).”
From 5. Facilitating Positive Health Behaviors and Well-being to Improve Health Outcomes:<i>Standards of Care in Diabetes—2023</i> (2023) · cites this paper as [311]
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“Evidence in other populations, including in those with Type 2 diabetes, suggests that physical activity promotion strategies based on theoretical models of behaviour change are more likely to result in sustained physical activity [11].”
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“Many of the techniques for changing patient behaviour identified in the present study have also been highlighted in a recent broader review of interventions to change patients’ physical activity behaviour in type 2 diabetes, which identified a number of specific BCTs as being associated with a greater change in HbA1c…”
Exosomes as Mediators of the Systemic Adaptations to Endurance Exercise
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“Prospective lifestyle interventions that include endurance exercise have been shown to improve glycemic control and insulin sensitivity in patients with both T2DM and dysglycemic obesity (Avery et al. 2012).”
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“Techniques such as those involving goal-setting and planning how to enact behavior or elicit social support were seldom considered, despite evidence that such techniques are generally effective at increasing physical activity in people with diabetes or obese people [63,64].”
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Japanese Clinical Practice Guideline for Diabetes 2016
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“While several traditional risk factors, such as poor diet [2,3], low physical activity [4,5], and poor sleep behaviors have been related to T2D [6,7], recent evidence suggests that ambient air pollution may also contribute to the development of the disease [8– 10].”
BackgroundExamining the theory‐effectiveness hypothesis: A systematic review of systematic reviews
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Physiological functions of peroxisome proliferator-activated receptor β
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“…change strategies for the promotion of PA are self-monitoring, providing feedback for behavior, goal setting, providing tools to facilitate behavior, action planning, social support, barrier identification, and providing information on the consequences specific to the individual [10,11,13].”
How can weight‐loss app designers' best engage and support users? A qualitative investigation
Tang, J., Abraham, C., Stamp, E., & Greaves, C. (2015) · British Journal of Health Psychology · doi:10.1111/bjhp.12114 · Cited by 152 · see citing works
“One technique not mentioned by our interviewees, which evidence suggest may be important to weight control was prompting problem solving (Avery, Flynn, van Wersch, Sniehotta, & Trenell, 2012; Greaves et al. , 2011).”
MethodCollaborative care for comorbid depression and diabetes: a systematic review and meta-analysis
Atlantis, E., Fahey, P., & Foster, J. (2014) · BMJ Open · doi:10.1136/bmjopen-2013-004706 · Cited by 179 · see citing works
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“19 29 Hence, diabetes-related behavioral and clinical outcomes can be improved through active engagement in e-and m-health interventions.”
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Sedentary Behavior and Incident Cancer: A Meta-Analysis of Prospective Studies
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“Although successful exercise interventions have significantly improved glycaemic control in adults with this condition [2], increasing MVPA in this population presents challenges, with a meta-analysis showing interventions typically achieve weak or moderate effects [3].”
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“Systematic reviews and metaanalyses suggest that behavioral interventions are more effective at increasing physical activity levels than standard clinical care in general-population adults and in patients with type 2 diabetes (15).”
Backgroundvan Vugt, M., de Wit, M., Cleijne, W., & Snoek, F. J. (2013) · Journal of Medical Internet Research · doi:10.2196/jmir.2800 · Cited by 112 · see citing works
Courneya, K. S., Vardy, J. L., O'Callaghan, C. J., Friedenreich, C. M., Campbell, K. L., Harry Prapavessis, A., Crawford, J., O’Brien, P., Dhillon, H. M., Jonker, D. J., et al. (2016) · Cancer Epidemiology Biomarkers & Prevention · doi:10.1158/1055-9965.epi-15-1267 · Cited by 114 · see citing works
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“intervention trials among adults with diabetes or to prevent gestational diabetes.(11-20) Few meta-analyses have addressed diabetes prevention in nonpregnant adults.”
BackgroundTerranova, C. O., Brakenridge, C. L., Lawler, S. P., Eakin, E. G., & Reeves, M. M. (2015) · Diabetes, Obesity and Metabolism · doi:10.1111/dom.12430 · Cited by 94 · see citing works
“29%; a magnitude similar to that observed in physical activity-only interventions in type 2 diabetes [39,40].”
BackgroundStephens, N. A., & Sparks, L. M. (2014) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2014-2545 · Cited by 97 · see citing works
Geidl, W., Semrau, J., & Pfeifer, K. (2014) · Disability and Rehabilitation · doi:10.3109/09638288.2014.891056 · Cited by 97 · see citing works
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“Furthermore, interventions targeting physical activity/exercise have also been shown to improve glucose control [41], body composition and liver fat in humans with fatty liver disease [53] and type 2 diabetes mellitus [54], irrespective of weight loss.”
BackgroundSelf-citationDiet Behavior Change Techniques in Type 2 Diabetes: A Systematic Review and Meta-analysis
Cradock, K. A., OLaighin, G. M., Finucane, F. M., McKay, R. C., Quinlan, L. R., Ginis, K. A. M., & Gainforth, H. L. (2017) · Diabetes Care · doi:10.2337/dc17-0462 · Cited by 87 · see citing works
“3 mmol/mol) as clinically significant, which follows the precedent set by others (14; 15).”
BackgroundMethodMaturana, F. M., Martus, P., Zipfel, S., & Niess, A. M. (2020) · Medicine & Science in Sports & Exercise · doi:10.1249/mss.0000000000002506 · Cited by 87 · see citing works
“Structured exercise training programs have already been shown to improve insulin and glucose metabolism (138,139).”
BackgroundOptimizing diabetes control in people with type 2 diabetes through nurse-led telecoaching
Odnoletkova, I., Goderis, G., Nobels, F., Fieuws, S., Aertgeerts, B., Annemans, L., & Ramaekers, D. (2016) · Diabetic Medicine · doi:10.1111/dme.13092 · Cited by 78 · see citing works
Strategies to Increase Physical Activity
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“Our intervention effect for MVPA is similar to what has been previously reported in type 2 diabetes (34).”
Self-tracking of Physical Activity in People With Type 2 Diabetes: A Randomized Controlled Trial
Kooiman, T. J. M., de Groot, M., Hoogenberg, K., Krijnen, W. P., van der Schans, C. P., & Kooy, A. (2018) · CIN: Computers, Informatics, Nursing · doi:10.1097/cin.0000000000000443 · Cited by 78 · see citing works
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“Elements of motivational interviewing have been used to alter physical activity behaviour in various populations other than COPD including patients with cancer, type II diabetes [37], obesity [38], congestive heart failure [39], adults at risk for cardiovascular disease [40, 41] and healthy adults [42, 43].”
MethodHaider, A., Saad, F., Doros, G. D., & Gooren, L. J. (2013) · Obesity Research & Clinical Practice · doi:10.1016/j.orcp.2013.10.005 · Cited by 70 · see citing works
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Celano, C. M., Albanese, A. M., Millstein, R. A., Mastromauro, C. A., Chung, W.-J., Campbell, K. A., Legler, S. R., Park, E. R., Healy, B. C., Collins, L. M., et al. (2018) · Psychosomatic Medicine · doi:10.1097/psy.0000000000000584 · Cited by 78 · see citing works
The Potential Impact of Displacing Sedentary Time in Adults with Type 2 Diabetes
Falconer, C., Page, A. S., Andrews, R. C., & Cooper, A. R. (2015) · Medicine & Science in Sports & Exercise · doi:10.1249/mss.0000000000000651 · Cited by 62 · see citing works
“In addition, lifestyle interventions to increase physical activity often have weak effects, with most people failing to achieve increases in MVPA sufficient to confer health benefits (2).”
BackgroundPlotnikoff, R. C., Wilczynska, M., Cohen, K. E., Smith, J. J., & Lubans, D. R. (2017) · Preventive Medicine · doi:10.1016/j.ypmed.2017.08.027 · Cited by 60 · see citing works
“eCoFit is an innovative, lifestyle program which has similar or greater magnitude of effects compared to previous research in this area (8, 9, 34, 36).”
BackgroundResultFredrix, M., McSharry, J., Flannery, C., Dinneen, S. F., & Byrne, M. (2018) · Psychology and Health · doi:10.1080/08870446.2018.1432760 · Cited by 61 · see citing works
“In a set of in-depth analyses, they identified which BCTs were utilised within these interventions and which BCTs may be associated with improvements in average blood glucose levels (measured in glycated haemoglobin level; HbA1c; Avery et al., 2012).”
BackgroundKeurhorst, M. N., van de Glind, I., do Amaral-Sabadini, M. B., Anderson, P., Kaner, E., Newbury‐Birch, D., Braspenning, J. C. C., Wensing, M., Heinen, M. M., & Laurant, M. G. H. (2015) · Addiction · doi:10.1111/add.13088 · Cited by 60 · see citing works
MacDonald, C. S., Ried‐Larsen, M., Soleimani, J., Alsawas, M., Lieberman, D. E., Ismail, A. S., Serafim, L. P., Yang, T., Prokop, L., Joyner, M., et al. (2021) · Diabetes/Metabolism Research and Reviews · doi:10.1002/dmrr.3444 · Cited by 57 · see citing works
Casey, B., Coote, S. B., Hayes, S., & Gallagher, S. M. (2018) · Archives of Physical Medicine and Rehabilitation · doi:10.1016/j.apmr.2017.12.013 · Cited by 58 · see citing works
Morton, K., Sutton, S. R., Hardeman, W., Troughton, J., Yates, T., Griffin, S. J., Davies, M. J., Khunti, K. K., & Eborall, H. (2015) · JMIR mhealth and uhealth · doi:10.2196/mhealth.5026 · Cited by 55 · see citing works
“With this in mind, the PROPELS follow-on support program also targeted other determinants of physical activity behavior change via the text message component and employed additional BCTs to achieve the overall intervention objectives (see Multimedia Appendix 1).”
BackgroundInfluentialIn Vitro Killing of Schistosomula of Schistosoma Mansoni by BCG and C. Parvum-Activated Macrophages
Mahmoud, A. A. F., Peters, P., Civil, R. H., & Remington, J. S. (1979) · The Journal of Immunology · doi:10.4049/jimmunol.122.5.1655 · Cited by 56 · see citing works
Patil, S. J., Ruppar, T. M., Koopman, R. J., Lindbloom, E. J., Elliott, S. G., Mehr, D. R., & Conn, V. S. (2018) · BMC Public Health · doi:10.1186/s12889-018-5326-8 · Cited by 54 · see citing works
Okwose, N. C., O’Brien, N., Charman, S. J., Cassidy, S., Brodie, D. A., Bailey, K. M., MacGowan, G. A., Jakovljević, D. G., & Avery, L. (2020) · BMJ Open · doi:10.1136/bmjopen-2019-036382 · Cited by 51 · see citing works
Self-citationHallsworth, K., Avery, L., & Trenell, M. I. (2016) · Current Gastroenterology Reports · doi:10.1007/s11894-016-0485-1 · Cited by 51 · see citing works
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“Retired 28 (19) 16 (19) 12 (19) 23 (20) 4 (13)”
InfluentialMcMillan, K. A., Kirk, A. F., Hewitt, A., & MacRury, S. M. (2016) · Journal of Diabetes Science and Technology · doi:10.1177/1932296816656018 · Cited by 48 · see citing works
“and subjectively measured physical activity, in addition to clinically significant improvements in HbA1c levels [1].”
BackgroundInfluentialMullan, B. A., MacPhail, M., Sharpe, L., MacCann, C., & Todd, J. (2014) · Diabetes Metabolic Syndrome and Obesity · doi:10.2147/dmso.s68428 · Cited by 46 · see citing works
Tsipa, A., O’Connor, D. B., Branley-Bell, D., Day, F., Hall, L. H., Sykes-Muskett, B., Wilding, S., Taylor, N., & Conner, M. (2021) · Health Psychology Review · doi:10.1080/17437199.2020.1760726 · Cited by 46 · see citing works
“Relatedly, implementation intentions (simple if-then plans) have been shown to be effective across a range of behaviours (Avery et al., 2012; Cradock et al., 2017; Hankonen et al., 2015; Lara et al., 2014) but rarely applied to cancer screening (Browne & Chan, 2011; Sheeran & Orbell, 2000) with…”
Kousoulis, A. A., Patelarou, E., Shea, S., Foss, C., Knutsen, I. R., Todorova, E., Roukova, P., Portillo, M. C., Pumar‐Méndez, M. J., Mujika, A., et al. (2014) · BMC Health Services Research · doi:10.1186/1472-6963-14-453 · Cited by 45 · see citing works
“and produced clinically significant improvements in long-term glucose control [105].”
BackgroundBaker, A., Sirois-Leclerc, H., & Tulloch, H. E. (2016) · Journal of Obesity · doi:10.1155/2016/6169890 · Cited by 46 · see citing works
Digital Platforms in the Assessment and Monitoring of Patients with Bipolar Disorder
Rajagopalan, A., Shah, P. R., Zhang, M. W., & Ho, R. (2017) · Brain Sciences · doi:10.3390/brainsci7110150 · Cited by 46 · see citing works
“usually based on behavioural modification, with a few exceptions such as prophylactic antibiotics and statins to prevent infection and hypercholesterolemia, respectively [45,50,51].”
BackgroundMoreau, M., Gagnon, M.-P., & Boudreau, F. (2015) · JMIR Research Protocols · doi:10.2196/resprot.4099 · Cited by 41 · see citing works
“In recent years, many reviewers also focused on effective behavior change techniques targeting physical activity [5,12,18,78-82,84].”
InfluentialBalducci, S., D’Errico, V., Haxhi, J., Sacchetti, M., Orlando, G., Cardelli, P., Vitale, M., Bollanti, L., Conti, F., Zanuso, S., et al. (2017) · Diabetes Care · doi:10.2337/dc17-0594 · Cited by 42 · see citing works
Bernard, P., Carayol, M., Gourlan, M., Boiché, J. C. S., Romain, A. J., Bortolon, C., Lareyre, O., & Ninot, G. (2016) · Health Education & Behavior · doi:10.1177/1090198116648667 · Cited by 41 · see citing works
Luoma, K., Leavitt, I. M., Marrs, J. C., Nederveld, A., Regensteiner, J. G., Dunn, A. L., Glasgow, R. E., & Huebschmann, A. G. (2017) · Translational Behavioral Medicine · doi:10.1007/s13142-017-0502-4 · Cited by 41 · see citing works
“Other review articles have lamented the lack of data on fidelity of intervention delivery in RCTs and have noted this as a limitation to identifying key moderators of PA interventions [76].”
BackgroundCelano, C. M., Gianangelo, T., Millstein, R. A., Chung, W., Wexler, D. J., Park, E. R., & Huffman, J. C. (2018) · The International Journal of Psychiatry in Medicine · doi:10.1177/0091217418791448 · Cited by 39 · see citing works
Huffman, J. C., Golden, J., Massey, C. N., Feig, E. H., Chung, W.-J., Millstein, R. A., Brown, L., Gianangelo, T., Healy, B. C., Wexler, D. J., et al. (2020) · Psychosomatic Medicine · doi:10.1097/psy.0000000000000840 · Cited by 40 · see citing works
Avery, L., Charman, S. J., Taylor, L., Flynn, D., Mosely, K., Speight, J., Lievesley, M. A., Taylor, R., Sniehotta, F. F., & Trenell, M. I. (2015) · Implementation Science · doi:10.1186/s13012-016-0459-6 · Cited by 38 · see citing works
“Booklet Support to select an appropriate PA/exercise, set PA goals, consider means of social support, identify barriers/problem solve, set short- and long-term goals, plan activity, self-monitor activity, prevent relapse Forethought (SCT) Subjective norms (TPB) Intention (TPB) Self-regulation (SCT) Perceived behaviour…”
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Lavie, C. J., Johannsen, N. M., Swift, D. L., Sénéchal, M., Earnest, C. P., Church, T. S., Hutber, A., Sallis, R. E., & Blair, S. N. (2014) · touchREVIEWS in Endocrinology · doi:10.17925/ee.2014.10.01.18 · Cited by 38 · see citing works
Huffman, J. C., Albanese, A. M., Campbell, K. A., Celano, C. M., Millstein, R. A., Mastromauro, C. A., Healy, B. C., Chung, W., Januzzi, J. L., Collins, L. M., et al. (2017) · Clinical Trials · doi:10.1177/1740774516673365 · Cited by 36 · see citing works
Change in sedentary time, physical activity, bodyweight, and HbA1c in high-risk adults
MCCARTHY, M., EDWARDSON, C. L., DAVIES, M. J., HENSON, J., GRAY, L., KHUNTI, K., & YATES, T. (2017) · Medicine & Science in Sports & Exercise · doi:10.1249/mss.0000000000001218 · Cited by 29 · see citing works
Nadal, I. P., Angkurawaranon, C., Singh, A., Choksomngam, Y., Sadana, V., Kock, L. S., Wattanapisit, A., Wiwatkunupakarn, N., & Kinra, S. (2024) · BMC Public Health · doi:10.1186/s12889-024-20612-8 · Cited by 40 · see citing works
“One of the two reviews assessed patients with diabetes and reported ‘Self-belief’ as an effective BCT for increasing physical activity [43].”
BackgroundMethodInfluentialPáez, A., Nunan, D., McCulloch, P. G., & Beard, D. J. (2024) · Journal of Clinical Epidemiology · doi:10.1016/j.jclinepi.2024.111610 · Cited by 36 · see citing works
A rapid review indicated higher recruitment rates in treatment trials than in prevention trials
Cooper, C. L., Hind, D., Duncan, R., Walters, S. J., Lartey, A., Lee, E. C., & Bradburn, M. J. (2014) · Journal of Clinical Epidemiology · doi:10.1016/j.jclinepi.2014.10.007 · Cited by 37 · see citing works
Dzielska, A., Mazur, J., Nałęcz, H., Oblacińska, A., & Fijałkowska, A. (2020) · Nutrients · doi:10.3390/nu12072128 · Cited by 36 · see citing works
“(2012) confirmed this relationship in adult studies [18] and Martyn-Nemeth et al.”
ResultAlmulhim, A. N., Hartley, H., Norman, P., Caton, S. J., Doğru, O. C., & Goyder, E. (2023) · BMC Public Health · doi:10.1186/s12889-022-14874-3 · Cited by 39 · see citing works
“A number of reviews have highlighted that the use of BCTs in interventions that target behaviours related to physical activity and maintaining a healthy weight may result in better management of HbA1c in people with T2DM [26].”
BackgroundEpigenetics in Precision Nutrition
Li, X., & Qi, L. (2022) · Journal of Personalized Medicine · doi:10.3390/jpm12040533 · Cited by 37 · see citing works
- Authors
- Avery, L., Flynn, D., van Wersch, A., Sniehotta, F. F., & Trenell, M. I.
- Affiliations
- Newcastle University (GB)
- School of Social Sciences and Law, Teesside University, Middlesbrough, U.K.
- Corresponding author
- Avery, Leah
- Venue
- Diabetes Care
- Publisher
- American Diabetes Association
- Published
- 2012-11-14
- Volume
- 35
- Issue
- 12
- Pages
- 2681-2689
- ISSN
- 0149-5992 (ISSN-L)
- 1935-5548
- PMC
- PMC3507564
- OpenAlex
- W2104983431
- Cited by
- 340
- References
- 55
- Citations by year
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- FWCI
- 2.72
- Type
- journal article
- Language
- en
- Open access
- hybrid
- doi.org
- Licence
- Locations
- Diabetes Care (publishedVersion, cc-by-nc-nd)
- Europe PMC (PubMed Central) (publishedVersion, cc-by-nc-nd)
- PubMed Central (publishedVersion, cc-by-nc-nd)
- PubMed (publishedVersion)
- Northumbria Research Link (Northumbria University) (acceptedVersion)
- TeesRep (Teesside University) (submittedVersion)
- Newcastle University ePrints (Newcastle Univesity)
- Funders
- National Institute for Health and Care Research (SRF-2011-04-017)
- Economic and Social Research Council (ES/G007470/1)
- Topics
- Health Sciences › Medicine › Physiology › Physical Activity and Health
- Social Sciences › Psychology › Applied Psychology › Behavioral Health and Interventions
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Management and Education
- Keywords
- type 2 diabetes, physical activity, behavioral interventions, glycemic control, HbA1c, body mass index, behaviour change techniques, intervention fidelity, provider training, free-living physical activity
- MeSH terms
- Blood Glucose, Diabetes Mellitus, Type 2, Humans, Exercise
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
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