Definitive endoderm of the mouse embryo: Formation, cell fates, and morphogenetic function

A genomic regulatory network for development

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The Zinc Finger-containing Transcription Factors GATA-4, -5, and -6

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Hedgehog signals regulate multiple aspects of gastrointestinal development

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Ubiquitin-mediated proteolysis: biological regulation via destruction

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Development of definitive endoderm from embryonic stem cells in culture

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Pax9 -deficient mice lack pharyngeal pouch derivatives and teeth and exhibit craniofacial and limb abnormalitiesPreprint

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Requirement for LIml in head-organizer function

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The winged-helix transcription factor HNF-3β is required for notochord development in the mouse embryo

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Depletion of definitive gut endoderm in <i>Sox17</i> -null mutant mice

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Dickkopf1 Is Required for Embryonic Head Induction and Limb Morphogenesis in the Mouse

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Nodal is a novel TGF-β-like gene expressed in the mouse node during gastrulation

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Vertebrate Endoderm Development

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A targeted mouse Otx2 mutation leads to severe defects in gastrulation and formation of axial mesoderm and to deletion of rostral brain

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Cripto is required for correct orientation of the anterior–posterior axis in the mouse embryo

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The homeobox gene Hex is required in definitive endodermal tissues for normal forebrain, liver and thyroid formation

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Induction and monitoring of definitive and visceral endoderm differentiation of mouse ES cells

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Cerberus-like is a secreted factor with neuralizing activity expressed in the anterior primitive endoderm of the mouse gastrula

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Characterization of mesendoderm: a diverging point of the definitive endoderm and mesoderm in embryonic stem cell differentiation culture

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Sonic hedgehog directs specialised mesoderm differentiation in the intestine and pancreas

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The role of Hoxa-3 in mouse thymus and thyroid development

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Expression of Cdx‐2 in the mouse embryo and placenta: Possible role in patterning of the extra‐embryonic membranes

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Expression of transcription factor HNF-4 in the extraembryonic endoderm, gut, and nephrogenic tissue of the developing mouse embryo: HNF-4 is a marker for primary endoderm in the implanting blastocyst.

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Early mouse endoderm is patterned by soluble factors from adjacent germ layers

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AnFgf8mouse mutant phenocopies human 22q11 deletion syndrome

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Origin and development of the zebrafish endoderm

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GATA4 is essential for formation of the proepicardium and regulates cardiogenesis

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Head induction by simultaneous repression of Bmp and Wnt signalling in Xenopus

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Genetic dissection ofnodalfunction in patterning the mouse embryo

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Morphogenesis of the murine node and notochordal plate

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Tbx1 mutation causes multiple cardiovascular defects and disrupts neural crest and cranial nerve migratory pathways

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The transcription factor HNF3β is required in visceral endoderm for normal primitive streak morphogenesis

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Cell fate decisions within the mouse organizer are governed by graded Nodal signalsPreprint

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Different thresholds of fibroblast growth factors pattern the ventral foregut into liver and lung

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Transcription factor GATA-4 regulates cardiac muscle-specific expression of the alpha-myosin heavy-chain gene.

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Failure of ventral closure and axial rotation in embryos lacking the proprotein convertase Furin

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Failure of egg cylinder elongation and mesoderm induction in mouse embryos lacking the tumor suppressor smad2

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Distinct populations of endoderm cells converge to generate the embryonic liver bud and ventral foregut tissues

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Reprogramming of intestinal differentiation and intercalary regeneration in Cdx 2 mutant mice

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Sox17 and β-catenin cooperate to regulate the transcription of endodermal genes

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Cell fate, morphogenetic movement and population kinetics of embryonic endoderm at the time of germ layer formation in the mouse

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Endoderm development: from patterning to organogenesis

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Sequential roles for Otx2 in visceral endoderm and neuroectoderm for forebrain and midbrain induction and specification

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<i>Hex</i> homeobox gene-dependent tissue positioning is required for organogenesis of the ventral pancreas

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casanova Plays an Early and Essential Role in Endoderm Formation in Zebrafish

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Formation of Multiple Hearts in Mice following Deletion of β-catenin in the Embryonic Endoderm

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The organizer of the mouse gastrula is composed of a dynamic population of progenitor cells for the axial mesoderm

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The Endoderm Plays an Important Role in Patterning the Segmented Pharyngeal Region in Zebrafish (Danio rerio)

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GATA6 Is Essential for Embryonic Development of the Liver but Dispensable for Early Heart Formation

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The regional pattern of retinoic acid synthesis by RALDH2 is essential for the development of posterior pharyngeal arches and the enteric nervous system

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Pax1 is expressed during development of the thymus epithelium and is required for normal T-cell maturation

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Ablation of specific expression domains reveals discrete functions of ectoderm- and endoderm-derived FGF8 during cardiovascular and pharyngeal development

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<i>Mixl1</i>is required for axial mesendoderm morphogenesis and patterning in the murine embryo

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Cell fate and cell lineage in the endoderm of the presomite mouse embryo, studied with an intracellular tracer

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IFITM/Mil/Fragilis Family Proteins IFITM1 and IFITM3 Play Distinct Roles in Mouse Primordial Germ Cell Homing and Repulsion

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Retinoid signaling is essential for patterning the endoderm of the third and fourth pharyngeal arches

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Disruption of thetalin gene arrests mouse development at the gastrulation stage

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Wild-Type Endoderm Abrogates the Ventral Developmental Defects Associated with GATA-4 Deficiency in the Mouse

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Dose-Dependent Interaction of Tbx1 and Crkl and Locally Aberrant RA Signaling in a Model of del22q11 Syndrome

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Retinoic acid generated by Raldh2 in mesoderm is required for mouse dorsal endodermal pancreas development

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Making Worm Guts: The Gene Regulatory Network of the Caenorhabditis elegans Endoderm

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Chordin and noggin promote organizing centers of forebrain development in the mouse

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Heart induction by Wnt antagonists depends on the homeodomain transcription factor Hex

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Pharyngeal arch patterning in the absence of neural crest

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Canonical Wnt Signaling and Its Antagonist Regulate Anterior-Posterior Axis Polarization by Guiding Cell Migration in Mouse Visceral Endoderm

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Induction of the mesendoderm in the zebrafish germ ring by yolk cell-derived TGF-β family signals and discrimination of mesoderm and endoderm by FGF

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Early endoderm development in vertebrates: lineage differentiation and morphogenetic function

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Formation of the definitive endoderm in mouse is a Smad2-dependent process

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A glimpse into the molecular entrails of endoderm formationPreprint

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Function of posterior HoxD genes in the morphogenesis of the anal sphincter

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Disabled-2 Is Essential for Endodermal Cell Positioning and Structure Formation during Mouse Embryogenesis

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Anterior mesendoderm induces mouse Engrailed genes in explant cultures

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Inactivation ofTbx1in the pharyngeal endoderm results in 22q11DS malformations

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Lim1 is required in both primitive streak-derived tissues and visceral endoderm for head formation in the mouse

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Identification of the vertebrate Iroquois homeobox gene family with overlapping expression during early development of the nervous system

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Establishment and Organization of Germ Layers in the Gastrulating Mouse Embryo

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Crkl deficiency disrupts Fgf8 signaling in a mouse model of 22q11 deletion syndromes.

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Differential expression of Sonic hedgehog along the anterior–posterior axis regulates patterning of pharyngeal pouch endoderm and pharyngeal endoderm-derived organs

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Functional ablation of the mouseLdb1gene results in severe patterning defects during gastrulation

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Differentiation and migration of endoderm in the rat and mouse at implantation

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Gastrula organiser and embryonic patterning in the mouse

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Animal–Vegetal Axis Patterning Mechanisms in the Early Sea Urchin Embryo

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Hindgut defects and transformation of the gastro‐intestinal tract in Tcf4−/−/Tcf1−/− embryos

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The morphogenetic role of midline mesendoderm and ectoderm in the development of the forebrain and the midbrain of the mouse embryo

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Polarity of the mouse embryo is anticipated before implantation

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A conserved retinoic acid responsive element in the murine Hoxb-1 gene is required for expression in the developing gut

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The Pem Homeobox Gene Is X-Linked and Exclusively Expressed in Extraembryonic Tissues during Early Murine Development

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Retinoic acid-induced developmental defects are mediated by RARβ/RXR heterodimers in the pharyngeal endoderm

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A null mutation of Hhex results in abnormal cardiac development,defective vasculogenesis and elevated Vegfa levels

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Gastrulation in the mouse embryo: Ultrastructural and molecular aspects of germ layer morphogenesis

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