CoChat
Sign Up
Cited by 147Eating Disorders and BehaviorsNutrition, Health and Food BehaviorChild and Adolescent Psychosocial and Emotional Development

Shared transmission of eating disorders and anxiety disorders

Keel, Pamela K., Klump, Kelly L., Miller, Kathryn B., McGue, Matt, Iacono, William G.·2005·International Journal of Eating Disorders
DOI 10.1002/eat.20168
Open this paper in CoChat — free account

Abstract

OBJECTIVE: Eating disorders have high comorbidity with mood, anxiety, and substance use disorders. Using twins from the population-based Minnesota Twin Family Study (MTFS), we examined comorbidity and shared transmission between eating pathology and these disorders. METHOD: Female twins (N = 672), ages 16-18 years, completed structured clinical interviews assessing anorexia nervosa and bulimia nervosa (as described in the 4th ed. of the Diagnostic and Statistical Manual of Mental Disorders [DSM-IV; American Psychiatric Association, 1994]), as well as mood, anxiety, and substance use disorders (as described in the 3rd Rev. ed. of the Diagnostic and Statistical Manual of Mental Disorders [DSM-III-R]). Shared transmission was examined using a discordant monozygotic (MZ) twin design. RESULTS: Significant comorbidity was found between eating disorders and major depression, anxiety disorders, and nicotine dependence. Within MZ twin pairs discordant for eating disorders (n = 14), non-eating-disordered cotwins demonstrated increased risk for anxiety disorders compared with controls. Similarly, within MZ twin pairs discordant for anxiety disorders (n = 52), non-anxiety-disordered cotwins demonstrated increased risk for eating disorders compared with controls. DISCUSSION: Findings support shared transmission between eating disorders and anxiety disorders. However, the nature of this shared diathesis remains unknown.

Integrity signals

Registry

Crossref · 10.1002/eat.20168

Cites

32 of 32 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

  • Anxiety disorders are common in families of individuals with anorexia nervosa.

    “Because anxiety disorders are common in families of individuals with AN (Keel et al., 2005)”

    From Factors associated with recovery from anorexia nervosa (2013) · cites this paper as Keel et al., 2005

Cites

Flagged first, then by citations

3 of the 35 references couldn’t be matched to a known paper.

Cited by

Sorted by citations

Related

Authors
Keel, P. K., Klump, K. L., Miller, K. B., McGue, M., & Iacono, W. G.
Affiliations
  • University of Iowa (US)
  • Michigan State University (US)
  • University of Minnesota (US)
ORCID
Venue
International Journal of Eating Disorders
Publisher
Wiley
Published
2005
Volume
38
Issue
2
Pages
99-105
ISSN
  • 0276-3478 (ISSN-L)
  • 1098-108X
DOI
10.1002/eat.20168
OpenAlex
W1964876234
Cited by
147
References
35
Citations by year
2025: 3 · 2024: 4 · 2023: 4 · 2022: 6 · 2021: 7 · 2020: 7 · 2019: 8 · 2018: 5 · 2017: 4 · 2016: 4 · 2015: 12 · 2014: 5 · 2013: 13 · 2012: 10
FWCI
12.73
Type
journal article
Language
en
Open access
closed
Licence
doi.wiley.com/10.1002/tdm_license_1.1 (tdm, 3895 d)
Locations
  • International Journal of Eating Disorders (publishedVersion)
  • PubMed (publishedVersion)
Funders
  • National Institute on Alcohol Abuse and Alcoholism (AA-09367)
  • National Institute of Mental Health (R01MH061836, MH61836)
  • National Institute on Drug Abuse (DA-05147)
Topics
  • Social Sciences › Psychology › Clinical Psychology › Eating Disorders and Behaviors
  • Health Sciences › Nursing › Nutrition and Dietetics › Nutrition, Health and Food Behavior
  • Social Sciences › Psychology › Clinical Psychology › Child and Adolescent Psychosocial and Emotional Development
Keywords
eating disorders, anxiety disorders, comorbidities, anorexia nervosa, bulimia nervosa, major depressive disorder, nicotine dependence, substance use disorders, monozygotic twins, discordant twins, Minnesota Twin Family Study, adolescent girls
MeSH terms
Adolescent, Anxiety Disorders, Feeding and Eating Disorders, Mental Disorders, Diseases in Twins, Female, Humans, Twins, Monozygotic, United States, Comorbidity, Prevalence, Case-Control Studies, Genetic Predisposition to Disease

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review