MAC1 mediates LPS-induced production of superoxide by microglia: The role of pattern recognition receptors in dopaminergic neurotoxicity

Neutrophil Extracellular Traps Kill Bacteria

Brinkmann, V., Reichard, U., Goosmann, C., Fauler, B., Uhlemann, Y., Weiss, D. S., Weinrauch, Y., & Zychlinsky, A. (2004) · Science · doi:10.1126/science.1092385 · Cited by 10,268 · see citing works

Resting microglial cells are highly dynamic surveillants of brain parenchyma in vivo

Nimmerjahn, A., Kirchhoff, F., & Helmchen, F. (2005) · Science · doi:10.1126/science.1110647 · Cited by 5,827 · see citing works

Microglia-mediated neurotoxicity: uncovering the molecular mechanisms

Block, M. L., Zecca, L., & Hong, J.-S. (2007) · Nature Reviews Neuroscience · doi:10.1038/nrn2038 · Cited by 4,110 · see citing works

Reactive oxygen intermediates as apparently widely used messengers in the activation of the NF‐kappa B transcription factor and HIV‐1.

Schreck, R., RIEBER, P., & Baeuerle, P. A. (1991) · The EMBO Journal · doi:10.1002/j.1460-2075.1991.tb07761.x · Cited by 3,816 · see citing works

Microglia and inflammation-mediated neurodegeneration: Multiple triggers with a common mechanism

Block, M. L., & Hong, J.-S. (2005) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2005.06.004 · Cited by 1,557 · see citing works

Role of Microglia in Inflammation-Mediated Neurodegenerative Diseases: Mechanisms and Strategies for Therapeutic Intervention

Liu, B., & Hong, J.-S. (2003) · The Journal of Pharmacology and Experimental Therapeutics · doi:10.1124/jpet.102.035048 · Cited by 1,095 · see citing works

Activation of innate immunity in the CNS triggers neurodegeneration through a Toll-like receptor 4-dependent pathway

Lehnardt, S., Massillon, L., Follett, P., Jensen, F. E., Ratan, R., Rosenberg, P. A., Volpe, J. J., & Vartanian, T. (2003) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1432609100 · Cited by 1,052 · see citing works

Toll-like receptor 4 imparts ligand-specific recognition of bacterial lipopolysaccharide.

Lien, E., Means, T., Heine, H., Yoshimura, A., Kusumoto, S., Fukase, K., Fenton, M., Oikawa, M., Qureshi, N., Monks, B., et al. (2000) · Journal of Clinical Investigation · doi:10.1172/jci8541 · Cited by 798 · see citing works

Receptors, Mediators, and Mechanisms Involved in Bacterial Sepsis and Septic Shock

van Amersfoort, E. S., van Berkel, T. J. C., & Kuiper, J. (2003) · Clinical Microbiology Reviews · doi:10.1128/cmr.16.3.379-414.2003 · Cited by 750 · see citing works

Microglial activation‐mediated delayed and progressive degeneration of rat nigral dopaminergic neurons: relevance to Parkinson's disease

Gao, H., Jiang, J., Wilson, B. C., Zhang, W., Hong, J., & Liu, B. (2002) · Journal of Neurochemistry · doi:10.1046/j.1471-4159.2002.00928.x · Cited by 690 · see citing works

The Toll-Like Receptor TLR4 Is Necessary for Lipopolysaccharide-Induced Oligodendrocyte Injury in the CNS

Lehnardt, S., Lachance, C., Patrizi, S., Lefebvre, S., Follett, P. L., Jensen, F. E., Rosenberg, P. A., Volpe, J. J., & Vartanian, T. K. (2002) · Journal of Neuroscience · doi:10.1523/jneurosci.22-07-02478.2002 · Cited by 684 · see citing works

A Novel Role for the β2 Integrin CD11b/CD18 in Neutrophil Apoptosis: A Homeostatic Mechanism in Inflammation

Coxon, A., Rieu, P., Barkalow, F. J., Askari, S., Sharpe, A. H., von Andrian, U. H., Arnaout, M. A., & Mayadas, T. N. (1996) · Immunity · doi:10.1016/s1074-7613(00)80278-2 · Cited by 627 · see citing works

Activation of protein kinase C by tyrosine phosphorylation in response to H 2 O 2

Konishi, H., Tanaka, M., Takemura, Y., Matsuzaki, H., Ono, Y., Kikkawa, U., & Nishizuka, Y. (1997) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.94.21.11233 · Cited by 604 · see citing works

NADPH Oxidase Mediates Lipopolysaccharide-induced Neurotoxicity and Proinflammatory Gene Expression in Activated Microglia

Qin, L., Liu, Y., Wang, T., Wei, S.-J., Block, M. L., Wilson, B., Liu, B., & Hong, J.-S. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.m307657200 · Cited by 574 · see citing works

A microtiter plate assay for superoxide dismutase using a water-soluble tetrazolium salt (WST-1)

Peskin, A. V., & Winterbourn, C. C. (2000) · Clinica Chimica Acta · doi:10.1016/s0009-8981(99)00246-6 · Cited by 548 · see citing works

Recognition and plasma clearance of endotoxin by scavenger receptors

Hampton, R. Y., Golenbock, D. T., Penman, M., Krieger, M., & Raetz, C. R. H. (1991) · Nature · doi:10.1038/352342a0 · Cited by 524 · see citing works

A Cell Surface Receptor Complex for Fibrillar β-Amyloid Mediates Microglial Activation

Bamberger, M. E., Harris, M. E., McDonald, D. R., Husemann, J., & Landreth, G. E. (2003) · The Journal of Neuroscience · doi:10.1523/jneurosci.23-07-02665.2003 · Cited by 501 · see citing works

Microglial Phagocytosis of Fibrillar β-Amyloid through a β1Integrin-Dependent Mechanism

Koenigsknecht-Talboo, J., & Landreth, G. E. (2004) · Journal of Neuroscience · doi:10.1523/jneurosci.2557-04.2004 · Cited by 444 · see citing works

Brain microglia constitutively express β-2 integrins

Akiyama, H., & McGeer, P. L. (1990) · Journal of Neuroimmunology · doi:10.1016/0165-5728(90)90055-r · Cited by 430 · see citing works

Role of Nitric Oxide in Inflammation‐Mediated Neurodegeneration

Liu, B., Gao, H., Wang, J., Jeohn, G., Cooper, C. L., & Hong, J. (2002) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.2002.tb04077.x · Cited by 425 · see citing works

Adhesion-promoting receptors on human macrophages recognize Escherichia coli by binding to lipopolysaccharide.

Wright, S. D., & Jong, M. T. C. (1986) · The Journal of Experimental Medicine · doi:10.1084/jem.164.6.1876 · Cited by 406 · see citing works

Toll-Like Receptor 4 on Nonhematopoietic Cells Sustains CNS Inflammation during Endotoxemia, Independent of Systemic Cytokines

Chakravarty, S., & Herkenham, M. (2005) · The Journal of Neuroscience · doi:10.1523/jneurosci.4268-04.2005 · Cited by 396 · see citing works

Lipopolysaccharide (LPS) binding protein opsonizes LPS-bearing particles for recognition by a novel receptor on macrophages.

Wright, S. D., Tobias, P. S., Ulevitch, R. J., & Ramos, R. (1989) · The Journal of Experimental Medicine · doi:10.1084/jem.170.4.1231 · Cited by 354 · see citing works

Naloxone Protects Rat Dopaminergic Neurons against Inflammatory Damage through Inhibition of Microglia Activation and Superoxide Generation

Liu, B., Du, L., & Hong, J.-S. (2000) · The Journal of Pharmacology and Experimental Therapeutics · doi:10.1016/s0022-3565(24)39275-4 · Cited by 347 · cited 2× · see citing works

Superoxide produced by activated neutrophils efficiently reduces the tetrazolium salt, WST-1 to produce a soluble formazan: A simple colorimetric assay for measuring respiratory burst activation and for screening anti-inflammatory agents

Tan, A. S., & Berridge, M. V. (2000) · Journal of Immunological Methods · doi:10.1016/s0022-1759(00)00156-3 · Cited by 330 · see citing works

Microglia enhance β‐amyloid peptide‐induced toxicity in cortical and mesencephalic neurons by producing reactive oxygen species

Qin, L., Liu, Y., Cooper, C. L., Liu, B., Wilson, B. C., & Hong, J. (2002) · Journal of Neurochemistry · doi:10.1046/j.1471-4159.2002.01210.x · Cited by 290 · see citing works

CR3 (CD11b, CD18): a phagocyte and NK cell membrane receptor with multiple ligand specificities and functions

Ross, G. D., & Větvička, V. (1993) · Clinical & Experimental Immunology · doi:10.1111/j.1365-2249.1993.tb03377.x · Cited by 286 · see citing works

Molecular consequences of activated microglia in the brain: overactivation induces apoptosis

Liu, B., Wang, K., Gao, H.-M., Mandavilli, B., Wang, J.-Y., & Hong, J.-S. (2001) · Journal of Neurochemistry · doi:10.1046/j.1471-4159.2001.t01-1-00216.x · Cited by 286 · see citing works

Regulation and Functional Involvement of Macrophage Scavenger Receptor MARCO in Clearance of Bacteria In Vivo

van der Laan, L. J. W., Döpp, E. A., Haworth, R., Pikkarainen, T., Kangas, M., Elomaa, O., Dijkstra, C. D., Gordon, S., Tryggvason, K., & Kraal, G. (1999) · The Journal of Immunology · doi:10.4049/jimmunol.162.2.939 · Cited by 279 · see citing works

Lipopolysaccharide (LPS) Signal Transduction and Clearance

Gegner, J. A., Ulevitch, R. J., & Tobias, P. S. (1995) · Journal of Biological Chemistry · doi:10.1074/jbc.270.10.5320 · Cited by 262 · see citing works

Synergistic Dopaminergic Neurotoxicity of the Pesticide Rotenone and Inflammogen Lipopolysaccharide: Relevance to the Etiology of Parkinson's Disease

Gao, H., Hong, J., Zhang, W., & Liu, B. (2003) · Journal of Neuroscience · doi:10.1523/jneurosci.23-04-01228.2003 · Cited by 251 · see citing works

In utero bacterial endotoxin exposure causes loss of tyrosine hydroxylase neurons in the postnatal rat midbrain

Ling, Z., Gayle, D. A., Ma, S. Y., Lipton, J. W., Tong, C. W., Hong, J., & Carvey, P. M. (2002) · Movement Disorders · doi:10.1002/mds.10078 · Cited by 241 · see citing works

CD14-dependent and CD14-independent signaling pathways in murine macrophages from normal and CD14 knockout mice stimulated with lipopolysaccharide or taxol

Perera, P., Vogel, S. N., Detore, G. R., Haziot, A., & Goyert, S. M. (1997) · The Journal of Immunology · doi:10.4049/jimmunol.158.9.4422 · Cited by 220 · see citing works

Role of reactive oxygen species in LPS‐induced production of prostaglandin E2in microglia

Wang, T., Qin, L., Liu, B., Liu, Y., Wilson, B. C., Eling, T. E., Langenbach, R. I., Taniura, S., & Hong, J. (2004) · Journal of Neurochemistry · doi:10.1046/j.1471-4159.2003.02242.x · Cited by 218 · see citing works

Complement Receptor 3 (CD11b/CD18) Mediates Type I and Type II Phagocytosis During Nonopsonic and Opsonic Phagocytosis, Respectively

Cabec, V. L., Carreno, S., Moisand, A., Bordier, C., & Maridonneau‐Parini, I. (2002) · The Journal of Immunology · doi:10.4049/jimmunol.169.4.2003 · Cited by 213 · see citing works

Interactive role of the toll‐like receptor 4 and reactive oxygen species in LPS‐induced microglia activation

Qin, L., Li, G., Qian, X., Liu, Y., Wu, X., Liu, B., Hong, J., & Block, M. L. (2005) · Glia · doi:10.1002/glia.20225 · Cited by 210 · see citing works

Lipopolysaccharide (LPS)-induced dopamine cell loss in culture: roles of tumor necrosis factor-α, interleukin-1β, and nitric oxide

Gayle, D. A., Ling, Z., Tong, C. W., Landers, T. M., Lipton, J. W., & Carvey, P. M. (2002) · Developmental Brain Research · doi:10.1016/s0165-3806(01)00315-7 · Cited by 201 · see citing works

Inflammation in Parkinson's disease.

McGeer, P. L., Yasojima, K., & McGeer, E. G. (2001) · PubMed · Cited by 196 · see citing works

Proteasome inhibition and aggregation in Parkinson's disease: a comparative study in untransfected and transfected cells

Biasini, E., Fioriti, L., Ceglia, I., Invernizzi, R. W., Bertoli, A., Chiesa, R., & Forloni, G. (2003) · Journal of Neurochemistry · doi:10.1046/j.1471-4159.2003.02152.x · Cited by 167 · see citing works

Characterization of a novel brain‐derived microglial cell line isolated from neonatal rat brain

Cheepsunthorn, P., Radov, L. A., Menzies, S. L., Reid, J., & Connor, J. R. (2001) · Glia · doi:10.1002/glia.1070 · Cited by 163 · see citing works

TLR4 Is the Signaling but Not the Lipopolysaccharide Uptake Receptor

Dunzendorfer, S., Lee, H., Soldau, K., & Tobias, P. S. (2004) · The Journal of Immunology · doi:10.4049/jimmunol.173.2.1166 · Cited by 162 · see citing works

Prenatal exposure to the bacteriotoxin lipopolysaccharide leads to long term losses of dopamine neurons in offspring a potential new model of parkinson s disease

Carvey, P. M. (2003) · Frontiers in bioscience · doi:10.2741/1158 · Cited by 161 · see citing works

Progressive dopamine neuron loss following supra-nigral lipopolysaccharide (LPS) infusion into rats exposed to LPS prenatally

Ling, Z., Zhu, Y., Tong, C. W., Snyder, J. A., Lipton, J. W., & Carvey, P. M. (2006) · Experimental Neurology · doi:10.1016/j.expneurol.2006.01.010 · Cited by 160 · see citing works

Binding and Internalization of Lipopolysaccharide by Cla-1, a Human Orthologue of Rodent Scavenger Receptor B1

Vishnyakova, T. G., Bocharov, A. V., Baranova, I. N., Chen, Z., Remaley, A. T., Csákó, G., Eggerman, T. L., & Patterson, A. P. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m211032200 · Cited by 160 · see citing works

Tau exon 10, whose missplicing causes frontotemporal dementia, is regulated by an intricate interplay of cis elements and trans factors

Wang, J., Gao, Q., Wang, Y., Lafyatis, R., Stamm, S., & Andreadis, A. (2004) · Journal of Neurochemistry · doi:10.1046/j.1471-4159.2003.02232.x · Cited by 126 · see citing works

Nonopsonic Phagocytosis of Zymosan andMycobacterium kansasiiby CR3 (CD11b/CD18) Involves Distinct Molecular Determinants and Is or Is Not Coupled with NADPH Oxidase Activation

Cabec, V. L., Cols, C., & Maridonneau‐Parini, I. (2000) · Infection and Immunity · doi:10.1128/iai.68.8.4736-4745.2000 · Cited by 120 · see citing works

Alzheimer disease and neuroinflammation

McGeer, P. L., McGeer, E. G., & Yasojima, K. (2000) · Springer eBooks · doi:10.1007/978-3-7091-6781-6_8 · Cited by 117 · see citing works

Combined toxicity of prenatal bacterial endotoxin exposure and postnatal 6-hydroxydopamine in the adult rat midbrain

Ling, Z. D., Chang, Q., Lipton, J. W., Tong, C. W., Landers, T. M., & Carvey, P. M. (2004) · Neuroscience · doi:10.1016/j.neuroscience.2003.12.017 · Cited by 114 · see citing works

Binding, internalization, and deacylation of bacterial lipopolysaccharide by human neutrophils.

Luchi, M., & Munford, R. S. (1993) · The Journal of Immunology · doi:10.4049/jimmunol.151.2.959 · Cited by 95 · see citing works

Mitogen-activated protein kinase (MAPK) activation by butylated hydroxytoluene hydroperoxide: implications for cellular survival and tumor promotion.

Guyton, K. Z., Gorospe, M., Kensler, T. W., & Holbrook, N. J. (1996) · PubMed · Cited by 93 · see citing works

Targeting of Scavenger Receptor Class B Type I by Synthetic Amphipathic α-Helical-containing Peptides Blocks Lipopolysaccharide (LPS) Uptake and LPS-induced Pro-inflammatory Cytokine Responses in THP-1 Monocyte Cells

Bocharov, A. V., Baranova, I. N., Vishnyakova, T. G., Remaley, A. T., Csákó, G., Fairwell, T., Patterson, A. P., & Eggerman, T. L. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.m314264200 · Cited by 70 · see citing works

Effects of Enhanced Striatal Dopamine Turnover In Vivo on Glutathione Oxidation

Loeffler, D. A., DeMaggio, A. J., Juneau, P. L., Havaich, M. K., & LeWitt, P. A. (1994) · Clinical Neuropharmacology · doi:10.1097/00002826-199408000-00009 · Cited by 61 · see citing works

Lipopolysaccharide-Binding Protein Critically Regulates Lipopolysaccharide-Induced IFN-β Signaling Pathway in Human Monocytes

Kato, A., Ogasawara, T., Homma, T., Saito, H., & Matsumoto, K. (2004) · The Journal of Immunology · doi:10.4049/jimmunol.172.10.6185 · Cited by 57 · see citing works

An Essential Role for Lipopolysaccharide-Binding Protein in Pulmonary Innate Immune Responses

Fan, M.-H., Klein, R. D., Steinstraesser, L., Merry, A. C., Nemzek, J. A., Remick, D. G., Wang, S. C., & Su, G. L. (2002) · Shock · doi:10.1097/00024382-200209000-00008 · Cited by 54 · see citing works

Primary Rat Mesencephalic Neuron-Glia, Neuron-Enriched, Microglia-Enriched, and Astroglia-Enriched Cultures

Liu, B., & Hong, J. (2003) · Humana Press eBooks · doi:10.1385/1-59259-358-5:387 · Cited by 50 · see citing works

Melatonin protects SHSY5Y neuronal cells but not cultured astrocytes from ischemia due to oxygen and glucose deprivation

Pei, Z., & Cheung, R. T. F. (2003) · Journal of Pineal Research · doi:10.1034/j.1600-079x.2003.00026.x · Cited by 42 · see citing works

Evidence for a CD14- and Serum-Independent Pathway in the Induction of Endotoxin-Tolerance in Human Monocytes and THP-1 Monocytic Cells

Heagy, W., Hansen, C., Nieman, K. M., & West, M. A. (2003) · Shock · doi:10.1097/00024382-200304000-00005 · Cited by 25 · see citing works

Is Endotoxin an Environmental Cause of Parkinson’s Disease?

Lange, J. H., Niehaus, I., & Thomulka, K. W. (2003) · Neuroepidemiology · doi:10.1159/000071196 · Cited by 6 · see citing works

Microglial Activation and Chronic Neurodegeneration

Lull, M. E., & Block, M. L. (2010) · Neurotherapeutics · doi:10.1016/j.nurt.2010.05.014 · Cited by 1,047 · see citing works

ROS Generation in Microglia: Understanding Oxidative Stress and Inflammation in Neurodegenerative Disease

Simpson, D. S. A., & Oliver, P. L. (2020) · Antioxidants · doi:10.3390/antiox9080743 · Cited by 1,044 · see citing works

Why neurodegenerative diseases are progressive: uncontrolled inflammation drives disease progression

Gao, H., & Hong, J. (2008) · Trends in Immunology · doi:10.1016/j.it.2008.05.002 · Cited by 822 · see citing works

The reactive oxygen species in macrophage polarization: reflecting its dual role in progression and treatment of human diseases

Tan, H.-Y., Wang, N., Li, S., Hong, M., Wang, X., & Feng, Y. (2016) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2016/2795090 · Cited by 657 · see citing works

Role of Microglia in Neurotrauma

Loane, D. J., & Byrnes, K. R. (2010) · Neurotherapeutics · doi:10.1016/j.nurt.2010.07.002 · Cited by 657 · see citing works

Therapies from Fucoidan; Multifunctional Marine Polymers

Fitton, J. H. (2011) · Marine Drugs · doi:10.3390/md9101731 · Cited by 394 · see citing works

HMGB1 acts on microglia Mac1 to mediate chronic neuroinflammation that drives progressive neurodegeneration

Gao, H.-M., Zhou, H., Zhang, F., Wilson, B. C., Kam, W., & Hong, J.-S. (2011) · The Journal of Neuroscience · doi:10.1523/jneurosci.3732-10.2011 · Cited by 369 · see citing works

Developmental Neuronal Death in Hippocampus Requires the Microglial CD11b Integrin and DAP12 Immunoreceptor

Wakselman, S., Béchade, C., Roumier, A., Bernard, D., Triller, A., & Bessis, A. (2008) · The Journal of Neuroscience · doi:10.1523/jneurosci.1006-08.2008 · Cited by 351 · see citing works

Estrogen anti-inflammatory activity in brain: A therapeutic opportunity for menopause and neurodegenerative diseases

Vegeto, E., Benedusi, V., & Maggi, A. C. (2008) · Frontiers in Neuroendocrinology · doi:10.1016/j.yfrne.2008.04.001 · Cited by 356 · see citing works

Transmission of α-synuclein-containing erythrocyte-derived extracellular vesicles across the blood-brain barrier via adsorptive mediated transcytosis: another mechanism for initiation and progression of Parkinson’s disease?

Matsumoto, J., Stewart, T., Sheng, L., Li, N., Bullock, K. M., Song, N., Shi, M. Y., Banks, W. A., & Zhang, J. (2017) · Acta Neuropathologica Communications · doi:10.1186/s40478-017-0470-4 · Cited by 294 · see citing works

Neuroinflammation is a key player in Parkinson’s disease and a prime target for therapy

Li, Q., Flood, P. M., & Hong, J. (2010) · Journal of Neural Transmission · doi:10.1007/s00702-010-0428-1 · Cited by 287 · see citing works

Neurodegeneration by Activation of the Microglial Complement-Phagosome Pathway

Bodea, L.-G., Wang, Y., Linnartz-Gerlach, B., Kopatz, J., Sinkkonen, L., Musgrove, R., Kaoma, T., Muller, A., Vallar, L., Di Monte, D. A., et al. (2014) · Journal of Neuroscience · doi:10.1523/jneurosci.5002-13.2014 · Cited by 234 · see citing works

Microglial CR3 Activation Triggers Long-Term Synaptic Depression in the Hippocampus via NADPH Oxidase

Zhang, J., Malik, A., Choi, H. B., Ko, R. W. Y., Dissing-Olesen, L., & MacVicar, B. A. (2014) · Neuron · doi:10.1016/j.neuron.2014.01.043 · Cited by 234 · see citing works

Inflammatory Aspects of Alzheimer Disease and Other Neurodegenerative Disorders

Schwab, C., & McGeer, P. L. (2008) · Journal of Alzheimer s Disease · doi:10.3233/jad-2008-13402 · Cited by 234 · see citing works

Particulate matter, oxidative stress and neurotoxicity

MohanKumar, S. M. J., Campbell, A., Block, M. L., & Veronesi, B. (2008) · NeuroToxicology · doi:10.1016/j.neuro.2007.12.004 · Cited by 235 · see citing works

Outdoor Ambient Air Pollution and Neurodegenerative Diseases: the Neuroinflammation Hypothesis

Jayaraj, R. L., Rodriguez, E. A., Wang, Y., & Block, M. L. (2017) · Current Environmental Health Reports · doi:10.1007/s40572-017-0142-3 · Cited by 233 · see citing works

Running exercise protects the substantia nigra dopaminergic neurons against inflammation-induced degeneration via the activation of BDNF signaling pathway

Wu, S.-Y., Wang, T.-F., Yu, L., Jen, C. J., Chuang, J.-I., Wu, F.-S., Wu, C.-W., & Kuo, Y.-M. (2011) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2010.09.006 · Cited by 206 · see citing works

NADPH oxidase- and mitochondria-derived reactive oxygen species in proinflammatory microglial activation: A bipartisan affair?

Bordt, E. A., & Polster, B. M. (2014) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2014.07.033 · Cited by 202 · see citing works

Microglial priming through the lung—brain axis: the role of air pollution‐induced circulating factors

Mumaw, C. L., Levesque, S., McGraw, C., Robertson, S., Lucas, S., Stafflinger, J. E., Campen, M. J., Hall, P. R., Norenberg, J. P., Anderson, T., et al. (2016) · The FASEB Journal · doi:10.1096/fj.201500047 · Cited by 188 · see citing works

NADPH oxidases in oxidant production by microglia: activating receptors, pharmacology and association with disease

Haslund‐Vinding, J., McBean, G., Jaquet, V, & Vilhardt, F. (2017) · British Journal of Pharmacology · doi:10.1111/bph.13425 · Cited by 169 · see citing works

NADPH oxidases in Parkinson’s disease: a systematic review

Bélarbi, K., Cuvelier, E., Destée, A., Gressier, B., & Chartier‐Harlin, M. (2017) · Molecular Neurodegeneration · doi:10.1186/s13024-017-0225-5 · Cited by 158 · see citing works

Central nervous system macrophages in progressive multiple sclerosis: relationship to neurodegeneration and therapeutics

Kamma, E., Lasisi, W. O., Libner, C., Ng, H.-A. S., & Plemel, J. R. (2022) · Journal of Neuroinflammation · doi:10.1186/s12974-022-02408-y · Cited by 137 · see citing works

Crosstalk between neuroinflammation and oxidative stress in epilepsy

Fabisiak, T., & Patel, M. (2022) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2022.976953 · Cited by 142 · see citing works

Silica-Based Nanoparticle Uptake and Cellular Response by Primary Microglia

Choi, J., Zheng, Q., Katz, H. E., & Guilarte, T. R. (2009) · Environmental Health Perspectives · doi:10.1289/ehp.0901534 · Cited by 134 · see citing works

Macrophage Antigen Complex-1 Mediates Reactive Microgliosis and Progressive Dopaminergic Neurodegeneration in the MPTP Model of Parkinson’s Disease

Hu, X., Zhang, D., Pang, H., Caudle, W. M., Li, Y., Gao, H., Liu, Y., Li, Q., Wilson, B. C., Monte, D. A. D., et al. (2008) · The Journal of Immunology · doi:10.4049/jimmunol.181.10.7194 · Cited by 125 · see citing works

Microglial priming in Alzheimer’s disease

Li, J.-W., Zong, Y., Cao, X.-P., Tan, L., & Tan, L. (2018) · Annals of Translational Medicine · doi:10.21037/atm.2018.04.22 · Cited by 122 · see citing works

Microglial physiopathology: how to explain the dual role of microglia after acute neural disorders?

Gomes‐Leal, W. (2012) · Brain and Behavior · doi:10.1002/brb3.51 · Cited by 115 · see citing works

Complement receptor 3 mediates NADPH oxidase activation and dopaminergic neurodegeneration through a Src-Erk-dependent pathway

Hou, L., Wang, K., Zhang, C., Sun, F., Che, Y., Zhao, X., Zhang, D., Li, H., & Wang, Q. (2018) · Redox Biology · doi:10.1016/j.redox.2017.09.017 · Cited by 104 · see citing works

The Endotoxin-Induced Neuroinflammation Model of Parkinson's Disease

Tüfekçi, K. U., Genç, Ş., & Genç, K. (2011) · Parkinson s Disease · doi:10.4061/2011/487450 · Cited by 108 · see citing works

Different Approaches to Modulation of Microglia Phenotypes After Spinal Cord Injury

Akhmetzyanova, E. R., Kletenkov, K., Mukhamedshina, Y. O., & Rizvanov, A. A. (2019) · Frontiers in Systems Neuroscience · doi:10.3389/fnsys.2019.00037 · Cited by 106 · see citing works

Clozapine Protects Dopaminergic Neurons from Inflammation-Induced Damage by Inhibiting Microglial Overactivation

Hu, X., Zhou, H., Zhang, D., Yang, S., Li, Q., Wu, H.-M., Chen, P.-S., Wilson, B. C., Gao, H., Lu, R., et al. (2011) · Journal of Neuroimmune Pharmacology · doi:10.1007/s11481-011-9309-0 · Cited by 100 · see citing works

Microglia dynamics in aging-related neurobehavioral and neuroinflammatory diseases

Javanmehr, N., Saleki, K., Alijanizadeh, P., & Rezaei, N. (2022) · Journal of Neuroinflammation · doi:10.1186/s12974-022-02637-1 · Cited by 103 · see citing works

Role of microglial redox balance in modulation of neuroinflammation

Innamorato, N. G., Lastres‐Becker, I., & Cuadrado, A. (2009) · Current Opinion in Neurology · doi:10.1097/wco.0b013e32832a3225 · Cited by 100 · see citing works

Integrin CD11b mediates α-synuclein-induced activation of NADPH oxidase through a Rho-dependent pathway

Hou, L., Bao, X., Zang, C., Yang, H., Sun, F., Che, Y., Wu, X., Li, S., Zhang, D., & Wang, Q. (2018) · Redox Biology · doi:10.1016/j.redox.2017.11.010 · Cited by 98 · see citing works

Microglial response to light‐induced photoreceptor degeneration in the mouse retina

Santos, A. M., Martín‐Oliva, D., Ferrer‐Martín, R. M., Tassi, M., Calvente, R., Sierra, A., Carrasco, M., Marín‐Teva, J. L., Navascués, J., & Cuadros, M. Á. (2009) · The Journal of Comparative Neurology · doi:10.1002/cne.22227 · Cited by 97 · see citing works

The role of <scp>MAC</scp> 1 in diesel exhaust particle‐induced microglial activation and loss of dopaminergic neuron function

Levesque, S., Taetzsch, T., Lull, M. E., Johnson, J. A., McGraw, C., & Block, M. L. (2013) · Journal of Neurochemistry · doi:10.1111/jnc.12231 · Cited by 94 · see citing works

Microglial MAC1 receptor and PI3K are essential in mediating β-amyloid peptide-induced microglial activation and subsequent neurotoxicity

Zhang, D., Hu, X., Li, Q., Chen, S., Zhou, H., Wilson, B. C., Miller, D. S., & Hong, J. (2011) · Journal of Neuroinflammation · doi:10.1186/1742-2094-8-3 · Cited by 87 · see citing works

Curcumin protects axons from degeneration in the setting of local neuroinflammation

Tegenge, M. A., Rajbhandari, L., Shrestha, S., Mithal, A., Hosmane, S., & Venkatesan, A. (2014) · Experimental Neurology · doi:10.1016/j.expneurol.2013.12.016 · Cited by 86 · see citing works

Molecular Targets and Related Biologic Activities of Fucoidan: A Review

Lin, Z. Y., Tan, X., Zhang, Y., Li, F., Luo, P., & Liu, H. (2020) · Marine Drugs · doi:10.3390/md18080376 · Cited by 81 · see citing works

Critical role of the Mac1/NOX2 pathway in mediating reactive microgliosis-generated chronic neuroinflammation and progressive neurodegeneration

Chen, S.-H., Oyarzabal, E. A., & Hong, J.-S. (2016) · Current Opinion in Pharmacology · doi:10.1016/j.coph.2015.10.001 · Cited by 76 · see citing works

Pesticides, Microglial NOX2, and Parkinson's Disease

Taetzsch, T., & Block, M. L. (2013) · Journal of Biochemical and Molecular Toxicology · doi:10.1002/jbt.21464 · Cited by 62 · see citing works

Periodontal Disease and Periodontal Disease-Related Bacteria Involved in the Pathogenesis of Alzheimer’s Disease

Matsushita, K., Yamada-Furukawa, M., Kurosawa, M., & Shikama, Y. (2020) · Journal of Inflammation Research · doi:10.2147/jir.s255309 · Cited by 59 · see citing works

Microglial CR3 promotes neuron ferroptosis via NOX2-mediated iron deposition in rotenone-induced experimental models of Parkinson's disease

Wang, Q., Liu, J., Zhang, Y., Li, Z., Zhao, Z., Jiang, W., Zhao, J., Hou, L., & Wang, Q. (2024) · Redox Biology · doi:10.1016/j.redox.2024.103369 · Cited by 49 · see citing works

Migration and Phagocytic Ability of Activated Microglia During Post-natal Development is Mediated by Calcium-Dependent Purinergic Signalling

Sunkaria, A., Bhardwaj, S., Halder, A., Yadav, A., & Sandhir, R. (2015) · Molecular Neurobiology · doi:10.1007/s12035-014-9064-3 · Cited by 44 · see citing works

Altered Expression Patterns of Inflammation-Associated and Trophic Molecules in Substantia Nigra and Striatum Brain Samples from Parkinson's Disease, Incidental Lewy Body Disease and Normal Control Cases

Walker, D. G., Lue, L., Serrano, G. E., Adler, C. H., Caviness, J. N., Sue, L. I., & Beach, T. G. (2016) · Frontiers in Neuroscience · doi:10.3389/fnins.2015.00507 · Cited by 44 · see citing works

Paying the circadian toll: The circadian response to LPS injection is dependent on the Toll-like receptor 4

Paladino, N., Leone, M. J., Plano, S. A., & Golombek, D. A. (2010) · Journal of Neuroimmunology · doi:10.1016/j.jneuroim.2010.04.015 · Cited by 43 · see citing works

Lipopolysaccharide-activated microglia lower P-glycoprotein function in brain microvascular endothelial cells

Matsumoto, J., Dohgu, S., Takata, F., Nishioku, T., Sumi, N., Machida, T., Takahashi, H., Yamauchi, A., & Kataoka, Y. (2012) · Neuroscience Letters · doi:10.1016/j.neulet.2012.07.004 · Cited by 37 · see citing works

Identification of a conserved gene signature associated with an exacerbated inflammatory environment in the hippocampus of aging rats

Pardo, J., Abba, M. C., Lacunza, E., Francelle, L., Morel, G. R., Outeiro, T. F., & Goya, R. G. (2017) · Hippocampus · doi:10.1002/hipo.22703 · Cited by 33 · see citing works

TLR-4-Dependent and -Independent Mechanisms of Fetal Brain Injury in the Setting of Preterm Birth

Breen, K. E., Brown, A. G., Burd, I. D., Chai, J., Friedman, A., & Elovitz, M. A. (2012) · Reproductive Sciences · doi:10.1177/1933719112438439 · Cited by 32 · see citing works

Agmatine Mitigates Inflammation-Related Oxidative Stress in BV-2 Cells by Inducing a Pre-Adaptive Response

Milosevic, K., Stevanović, I. D., Bozic, I. D., Milosevic, A., Janjic, M. M., Laketa, D., Bjelobaba, I. M., Lavrnja, I. C., & Savić, D. Z. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23073561 · Cited by 31 · see citing works

2,5-Hexanedione induces dopaminergic neurodegeneration through integrin αMβ2/NADPH oxidase axis-mediated microglial activation

Zhang, C., Hou, L., Yang, J., Che, Y., Sun, F., Li, H., & Wang, Q. (2018) · Cell Death and Disease · doi:10.1038/s41419-017-0091-7 · Cited by 32 · see citing works

Characterization and expression of NADPH oxidase in LPS-, poly(I:C)- and zymosan-stimulated trout (Oncorhynchus mykiss W.) macrophages

Boltaña, S., Doñate, C., Goetz, F. W., MacKenzie, S. A., & Balasch, J. C. (2008) · Fish & Shellfish Immunology · doi:10.1016/j.fsi.2008.11.011 · Cited by 31 · see citing works

Caspases orchestrate microglia instrumental functions

Shen, X., Venero, J. L., Joseph, B., & Burguillos, M. Á. (2018) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2018.09.007 · Cited by 30 · see citing works

Low level bacterial endotoxin activates two distinct signaling pathways in human peripheral blood mononuclear cells

Blomkalns, A. L., Stoll, L. L., Shaheen, W. H., Romig‐Martin, S. A., Dickson, E. W., Weintraub, N. L., & Denning, G. M. (2011) · Journal of Inflammation · doi:10.1186/1476-9255-8-4 · Cited by 28 · see citing works

Neurotoxic effect of 2,5-hexanedione on neural progenitor cells and hippocampal neurogenesis

Kim, M., Park, H. R., Park, M.-K., Kim, S. J., Kwon, M., Yu, B. P., Chung, H. Y., Kim, H. S., Kwack, S. J., Kang, T. S., et al. (2009) · Toxicology · doi:10.1016/j.tox.2009.03.013 · Cited by 28 · see citing works

An association between mitochondria and microglia effector function: what do we think we know?

Harry, G. J., Childers, G. M., Giridharan, S., & Hernandes, I. L. (2020) · Neuroimmunology and Neuroinflammation · doi:10.20517/2347-8659.2020.07 · Cited by 27 · see citing works

Low molecular weight polysialic acid prevents lipopolysaccharide‐induced inflammatory dopaminergic neurodegeneration in humanized SIGLEC11 transgenic mice

Liao, H., Winkler, J., Wißfeld, J., Shahraz, A., Klaus, C., & Neumann, H. (2021) · Glia · doi:10.1002/glia.24073 · Cited by 26 · see citing works

A Novel Compound ITC-3 Activates the Nrf2 Signaling and Provides Neuroprotection in Parkinson’s Disease Models

Lee, J. A., Son, H. J., Park, K. D., Han, S. H., Shin, N., Kim, J. H., Kim, H. R., Kim, D. J., & Hwang, O. (2015) · Neurotoxicity Research · doi:10.1007/s12640-015-9550-z · Cited by 25 · see citing works

A Causal Relationship in Spinal Cord Injury Rat Model Between Microglia Activation and EGFR/MAPK Detected by Overexpression of MicroRNA-325-3p

Yan, P., Wu, X.-J., Liu, X., Cai, Y., Shao, C., & Zhu, G. (2019) · Journal of Molecular Neuroscience · doi:10.1007/s12031-019-01297-w · Cited by 24 · see citing works

Does gut brain axis has an impact on Parkinson’s disease (PD)?

Elangovan, A., Dahiya, B., Kirola, L., Iyer, M., Jeeth, P., Maharaj, S., Kumari, N., Lakhanpal, V., Michel, T. M., Rao, K. R. S. S., et al. (2023) · Ageing Research Reviews · doi:10.1016/j.arr.2023.102171 · Cited by 22 · see citing works

Immunology primer for neurosurgeons and neurologists part 2: Innate brain immunity

Blaylock, R. L. (2013) · Surgical Neurology International · doi:10.4103/2152-7806.118349 · Cited by 22 · see citing works

Increasing Tau 4R Tau Levels Exacerbates Hippocampal Tau Hyperphosphorylation in the hTau Model of Tauopathy but Also Tau Dephosphorylation Following Acute Systemic Inflammation

Barron, M. R., Gartlon, J. E., Dawson, L. A., Atkinson, P. J., & Pardon, M. (2020) · Frontiers in Immunology · doi:10.3389/fimmu.2020.00293 · Cited by 20 · see citing works

MicroRNA-gene regulatory network of TLR signaling in neuroinflammation-induced Parkinson’s disease: a bioinformatics approach

Singh, G., & Khatri, D. K. (2024) · Network Modeling Analysis in Health Informatics and Bioinformatics · doi:10.1007/s13721-024-00445-6 · Cited by 20 · see citing works

Soybean-derived Bowman-Birk inhibitor inhibits neurotoxicity of LPS-activated macrophages

Li, J., Li, Y., Cook, D. R., Wang, X., Liu, J., Kolson, D. L., Persidsky, Y., & Ho, W. (2011) · Journal of Neuroinflammation · doi:10.1186/1742-2094-8-15 · Cited by 20 · see citing works

Guard of Delinquency? A Role of Microglia in Inflammatory Neurodegenerative Diseases of the CNS

Wu, W., Shao, J., Lu, H., Xu, J., Zhu, A., Fang, W., & Hui, G. (2014) · Cell Biochemistry and Biophysics · doi:10.1007/s12013-014-9872-0 · Cited by 19 · see citing works

DAP12 and CD11b contribute to the microglial-induced death of dopaminergic neurons in vitro but not in vivo in the MPTP mouse model of Parkinson’s disease

Kinugawa, K., Monnet, Y., Béchade, C., Alvarez‐Fischer, D., Hirsch, É. C., Bessis, A., & Hunot, S. (2013) · Journal of Neuroinflammation · doi:10.1186/1742-2094-10-82 · Cited by 19 · see citing works

Circulating HMGB1 is elevated in veterans with Gulf War Illness and triggers the persistent pro-inflammatory microglia phenotype in male C57Bl/6J mice

Garza-Lombó, C., Thang, M., Greve, H. J., Mumaw, C. L., Messenger, E. J., Ahmed, C., Quinn, E. K., Sullivan, K. A., & Block, M. L. (2021) · Translational Psychiatry · doi:10.1038/s41398-021-01517-1 · Cited by 18 · see citing works

Impact of Enzymatically Extracted High Molecular Weight Fucoidan on Lipopolysaccharide-Induced Endothelial Activation and Leukocyte Adhesion

Kirsten, N., Ohmes, J., Mikkelsen, M. D., Nguyen, T. T., Blümel, M., Wang, F., Taşdemir, D., Seekamp, A., Meyer, A. S., & Fuchs, S. (2023) · Marine Drugs · doi:10.3390/md21060339 · Cited by 16 · see citing works

Synthetic Triterpenoid CDDO Derivatives Modulate Cytoprotective or Immunological Properties in Astrocytes, Neurons, and Microglia

Graber, D. J., Park, P. J., Hickey, W. F., & Harris, B. T. (2010) · Journal of Neuroimmune Pharmacology · doi:10.1007/s11481-010-9240-9 · Cited by 15 · see citing works

Activation of the MAC1-ERK1/2-NOX2 Pathway Is Required for LPS-Induced Sustaining Reactive Microgliosis, Chronic Neuroinflammation and Neurodegeneration

Chen, S., Han, S., Hu, C.-F., Zhou, R., Gao, Y., Tu, D., Gao, H., Feng, J., Wang, Y., Lu, R., et al. (2022) · Antioxidants · doi:10.3390/antiox11061202 · Cited by 13 · see citing works

CD11b-NOX2 mutual regulation-mediated microglial exosome release contributes to rotenone-induced inflammation and neurotoxicity in BV2 microglia and primary cultures

Su, L., Guo, Z., Liu, J., Ma, Y., Zhang, X., Hou, L., Wang, Q., Jiang, W., & Wang, Q. (2024) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2024.09.008 · Cited by 13 · see citing works

Microglial NOX2 as a therapeutic target in traumatic brain injury: Mechanisms, consequences, and potential for neuroprotection

Bano, N., Khan, S., Ahamad, S., Dar, N. J., Alanazi, H. H., Nazir, A., & Bhat, S. A. (2025) · Ageing Research Reviews · doi:10.1016/j.arr.2025.102735 · Cited by 12 · see citing works

Microglia-Induced Maladaptive Plasticity Can Be Modulated by NeuropeptidesIn Vivo

Morara, S., Colangelo, A. M., & Provini, L. (2015) · Neural Plasticity · doi:10.1155/2015/135342 · Cited by 11 · see citing works

In Vitro Models for Neuroelectrodes: A Paradigm for Studying Tissue–Materials Interactions in the Brain

Reichert, W. M. (2007) · CRC Press eBooks · doi:10.1201/9781420009309-13 · Cited by 9 · see citing works

Introduction to spinal cord injury as clinical pathology

Papa, S., Mauri, E., Rossi, F., Perale, G., & Veglianese, P. (2019) · Elsevier eBooks · doi:10.1016/b978-0-08-102807-0.00001-6 · Cited by 8 · see citing works

METTL3/ALKBH5‐Mediated N6‐Methyladenosine Modification Drives Macrophage M1 Polarization via the SLC15A3‐TASL‐IRF5 Signaling Axis in Psoriasis

Huang, T., Chen, S., Ding, K., Yuan, L., Lv, W., Chen, K., Liu, Y., Ma, D.-Z., Zhang, X., Wang, X., et al. (2025) · Advanced Science · doi:10.1002/advs.202501408 · Cited by 9 · see citing works

Hypoxia with inflammation and reperfusion alters membrane resistance by dynamically regulating voltage-gated potassium channels in hippocampal CA1 neurons

Yang, Y., Choi, J. H., & Rah, J. (2021) · Molecular Brain · doi:10.1186/s13041-021-00857-9 · Cited by 7 · see citing works

Development of non-viral vehicles for targeted gene transfer into microglia via the integrin receptor CD11b

Smolny, M., Rogers, M., Shafton, A. D., Rush, R. A., & Stebbing, M. J. (2014) · Frontiers in Molecular Neuroscience · doi:10.3389/fnmol.2014.00079 · Cited by 7 · see citing works

Microglial activation decreases retention of the protease inhibitor saquinavir: implications for HIV treatment

Dallas, S., Block, M. L., Thompson, D. M., Bonini, M. G., Ronaldson, P. T., Bendayan, R., & Miller, D. S. (2013) · Journal of Neuroinflammation · doi:10.1186/1742-2094-10-58 · Cited by 7 · see citing works

Local partial depletion of CD 11b+ cells and their influence on choroidal neovascularization using the CD 11b‐ HSVTK mouse model

Brockmann, C., Kociok, N., Dege, S., Davids, A., Brockmann, T., Miller, K. R., & Joussen, A. M. (2018) · Acta Ophthalmologica · doi:10.1111/aos.13716 · Cited by 6 · see citing works

Scavenger receptor A in immunity and autoimmune diseases: Compelling evidence for targeted therapy

Xie, Y., Yuan, J., Li, Z., & Hu, F. (2022) · Expert Opinion on Therapeutic Targets · doi:10.1080/14728222.2022.2072729 · Cited by 7 · see citing works

Post-Translational Oxidation Modifications of Blood Plasma Proteins of Cosmonauts after a Long-term Flight: Part I

Larina, I. M., Brzhzovsky, A. G., Nosovsky, A. M., Kononikhin, A. S., & Orlov, O. I. (2020) · Human Physiology · doi:10.1134/s0362119720050072 · Cited by 6 · see citing works

Roles of Microglia in Inflammation-Mediated Neurodegeneration: Models, Mechanisms, and Therapeutic Interventions for Parkinson's Disease

Gao, H., Tu, D., Gao, Y., Liu, Q., Yang, R., Liu, Y., Guan, T., & Hong, J. (2017) · Advances in neurotoxicology · doi:10.1016/bs.ant.2017.07.005 · Cited by 5 · see citing works

Assessing the Influence of Neuroinflammation on Neurogenesis: In Vitro Models Using Neural Stem Cells and Microglia as Valuable Research Tools

Bruno, P., Ins, M., Caetana, M., & Ins, M. (2012) · InTech eBooks · doi:10.5772/30723 · Cited by 3 · see citing works

The Energy Crisis in Parkinson’s Disease: A Therapeutic Target

Abou-Hamdan, M., Cornille, E., Khrestchatisky, M., de, M. B. A. B., & Gharib, B. (2011) · InTech eBooks · doi:10.5772/17369 · Cited by 4 · see citing works

Neurotoxicity in Depression

Smaga, I., Krzyżanowska, W., Pomierny, B., Maciejska, A., Skórkowska, A., Budziszewska, B., Pilc, A., & Nowak, G. (2022) · Springer eBooks · doi:10.1007/978-3-031-15080-7_176 · Cited by 5 · see citing works

Anatomical location of injected microglia in different activation states and time course of injury determines survival of retinal ganglion cells after optic nerve crush

Siddiqui, A. M., Sabljic, T. F., & Ball, A. K. (2022) · International Journal of Neuroscience · doi:10.1080/00207454.2022.2142579 · Cited by 3 · see citing works

Role of Neurotoxicity in Depression

Smaga, I., Krzyżanowska, W., Pomierny, B., Budziszewska, B., Pilc, A., & Nowak, G. (2014) · Springer eBooks · doi:10.1007/978-1-4614-5836-4_176 · Cited by 3 · see citing works

Microglial activation in a mouse model of α-synuclein overexpression

Maguire‐Zeiss, K. A., Su, X., & Federoff, H. J. (2008) · Elsevier eBooks · doi:10.1016/b978-0-12-374028-1.00040-3 · Cited by 3 · see citing works

A novel role of peptidyl-prolyl isomerase-1 as inducer of IL-6 expression in systemic lupus erythematosus

Takeno, M. R., & Gunn, J. B. (2015) · American Journal of BioMedicine · doi:10.18081/2333-5106/015-2/439-450 · Cited by 2 · see citing works

Functionally charged polystyrene particles activate immortalized mouse microglia (BV2): cellular and genomic response

Veronesi, B., Tajuba, J., Saleh, N., Veronesi, B., Tajuba, J., Saleh, N., Ward, W. O., Hester, S., Carter, J., & Lowry, G. V. (2008) · Nanotoxicology · doi:10.1080/17435390802296347 · Cited by 2 · see citing works

Does generalized hypo-oxygenation (hypoxia) allow endotoxin into the brain through the blood brain barrier, thus increasing the risk for Parkinson disease?

Lange, J. H., Niehaus, I., & Cegolon, L. (2016) · Croatian Medical Journal · doi:10.3325/cmj.2016.57.406 · Cited by 2 · see citing works

Inflammatory Responses and Regulation in Parkinson’s Disease

Lynda, J., & Patrick, M. (2011) · InTech eBooks · doi:10.5772/18708

The role of the innate immune system in the clearance of apoptotic cells

Thomas, L. (2012) · Aston Publications Explorer (Aston University) · doi:10.48780/publications.aston.ac.uk.00016432

Molecular characterisation of the underlying mechanisms of pathogen-associated molecular pattern (PAMP) recognition in fish

Boltaña, S. (2011) · TDX (Tesis Doctorals en Xarxa)

Complement-mediated microglial priming : an in vitro study

Wheat, R. (2016) · ORCA Online Research @Cardiff (Cardiff University)

Functional Roles of the SWI/SNF ATPase Brahma Related Gene 1 (BRG1) and Special AT-Rich Binding Protein (SATB1) in Virus Response and Innate Immunity

Torti, D. (2012) · TSpace (University of Toronto)

Inflammation-Mediated Neurodegeneration: Models, Mechanisms, and Therapeutic Interventions for Neurodegenerative Diseases

Gao, H., Gao, Y., Tu, D., Liu, Y., Zhou, H., & Hong, J. (2017) · Wiley-VCH eBooks · doi:10.1002/9783527692156.ch48

Terapia génica y reprogramación celular en modelos animales de envejecimiento cerebral

Pardo, J. (2017) · doi:10.35537/10915/64088

Inflammation and Parkinson's disease : the effect of Poly(I:C) in a toxin-based model of Parkinson's disease

Bobyn, J. (2011) · doi:10.22215/etd/2011-06950

Macrophage Antigen Complex-1 Mediates Reactive Microgliosis and Progressive Dopaminergic Neurodegeneration in the MPTP Model of Parkinson’s Disease

Hu, X., Zhang, D., Pang, H., Caudle, W. M., Li, Y., Gao, H., Liu, Y., Li, Q., Wilson, B. C., Monte, D. A. D., et al. (2008) · The Journal of Immunology · doi:10.4049/jimmunol.181.10.7194 · Cited by 125 · see citing works

NADPH Oxidase Mediates Lipopolysaccharide-induced Neurotoxicity and Proinflammatory Gene Expression in Activated Microglia

Qin, L., Liu, Y., Wang, T., Wei, S.-J., Block, M. L., Wilson, B., Liu, B., & Hong, J.-S. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.m307657200 · Cited by 574 · see citing works

Interactive role of the toll‐like receptor 4 and reactive oxygen species in LPS‐induced microglia activation

Qin, L., Li, G., Qian, X., Liu, Y., Wu, X., Liu, B., Hong, J., & Block, M. L. (2005) · Glia · doi:10.1002/glia.20225 · Cited by 210 · see citing works

Minimally Toxic Dose of Lipopolysaccharide and α-Synuclein Oligomer Elicit Synergistic Dopaminergic Neurodegeneration: Role and Mechanism of Microglial NOX2 Activation

Zhang, W., Gao, J.-H., Yan, Z.-F., Huang, X.-Y., Guo, P., Sun, L., Liu, Z., Hu, Y., Zuo, L.-J., Yu, S.-Y., et al. (2018) · Molecular Neurobiology · doi:10.1007/s12035-016-0308-2 · Cited by 37 · see citing works

Superoxide anion contributes to the induction of tumor necrosis factor alpha (TNFα) through activation of the MKK3/6-p38 MAPK cascade in rat microglia

Yoshino, Y., Yamamoto, S., Kohsaka, S., Oshiro, S., & Nakajima, K. (2011) · Brain Research · doi:10.1016/j.brainres.2011.09.009 · Cited by 9 · see citing works