The DOI matches its Crossref record; 18 of the 18 references it cites were found in a registry or an index.
Persistent default‐mode network connectivity during light sedation
Open accessAbstract
The default‐mode network (DMN) is a set of specific brain regions whose activity, predominant in the resting‐state, is attenuated during cognitively demanding, externally‐cued tasks. The cognitive correlates of this network have proven difficult to interrogate, but one hypothesis is that regions in the network process episodic memories and semantic knowledge integral to internally‐generated mental activity. Here, we compare default‐mode functional connectivity in the same group of subjects during rest and conscious sedation with midazolam, a state characterized by anterograde amnesia and a reduced level of consciousness. Although the DMN showed functional connectivity during both rest and conscious sedation, a direct comparison found that there was significantly reduced functional connectivity in the posterior cingulate cortex during conscious sedation. These results confirm that low‐frequency oscillations in the DMN persist and remain highly correlated even at reduced levels of consciousness. We hypothesize that focal reductions in DMN connectivity, as shown here in the posterior cingulate cortex, may represent a stable correlate of reduced consciousness. Hum Brain Mapp, 2008. © 2008 Wiley‐Liss, Inc.
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Cites
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Functional connectivity in the resting brain: a network analysis of the default mode hypothesis
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Self-citationGreicius, M. D., Srivastava, G., Reiss, A. L., & Menon, V. (2004) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0308627101 · Cited by 3,684
Self-citationInvestigations into resting-state connectivity using independent component analysis
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“, 2006] and those that involve self-evaluative judgments [Johnson et al., 2007; Kelley et al., 2002] tend to activate regions in the DMN.”
BackgroundThe neural bases of momentary lapses in attention
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“This hypothesis is supported by fMRI studies of conscious rest [Beckmann et al., 2005; Fox et al., 2005; Fransson, 2005; Greicius et al., 2003; Laufs et al., 2003] and cognitively undemanding tasks [Greicius and Menon, 2004; Greicius et al.”
MethodCoherent spontaneous activity identifies a hippocampal-parietal memory network
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“Whereas nearly any cognitively demanding functional task will induce deactivation in the DMN, tasks that require retrieval of episodic memories [Buckner et al., 2005; Maddock et al., 2001; Maguire and Mummery, 1999; Vincent et al., 2006] and those that involve self-evaluative judgments [Johnson et al.”
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Self-citationRemembering familiar people: the posterior cingulate cortex and autobiographical memory retrieval
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Conn : A Functional Connectivity Toolbox for Correlated and Anticorrelated Brain Networks
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The brain's default mode network
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Large-scale brain networks and psychopathology: a unifying triple network model
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Self-citationDynamic functional connectivity: Promise, issues, and interpretations
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Self-citationToward discovery science of human brain function
Biswal, B. B., Mennes, M., Zuo, X.-N., Gohel, S., Kelly, C., Smith, S. M., Beckmann, C. F., Adelstein, J. S., Buckner, R. L., Colcombe, S., et al. (2010) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0911855107 · Cited by 2,970
Self-citation
Metadata
- Authors
- Greicius, M. D., Kiviniemi, V., Tervonen, O., Vainionpää, V., Alahuhta, S., Reiss, A. L., & Menon, V.
- Venue
- Human Brain Mapping
- Publisher
- Wiley
- Published
- 2008-01-24
- Volume
- 29
- Issue
- 7
- Pages
- 839-847
- ISSN
- 1065-9471 (ISSN-L)
- 1097-0193
- OpenAlex
- W2142794733
- Cited by
- 519
- References
- 18
- FWCI
- 20.45
- Type
- journal article
- Language
- en
- Open access
- green
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