Fronto-cingulate effective connectivity in obsessive compulsive disorder: a study with fMRI and dynamic causal modeling
Open accessAbstract
Evidence suggests that obsessive compulsive disorder (OCD) is associated with an overactive error control system. A key role in error detection and control has been ascribed to the fronto-cingulate system. However, the exact functional interplay between the single components of this network in OCD is largely unknown. Therefore, the present study combined a univariate data analysis and effective connectivity analysis using dynamic causal modeling (DCM) to examine error control in 21 patients with OCD and 21 matched healthy controls. All subjects performed an adapted version of the Stroop color-word task while undergoing fMRI scans. Enhanced activation in the fronto-cingulate system could be detected in OCD patients during the incongruent task condition. Additionally, task-related modulation of effective connectivity from the dorsal ACC to left DLPFC was significantly stronger in OCD patients. These findings are consistent with an overactive error control system in OCD subserving suppression of prepotent responses during decision-making.
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Increased connectivity between the DLPFC and ACC was found in OCD patients compared with healthy controls during performance on a Stroop task.
“Schlosser et al. (2010) used dynamic causal modeling (DCM) to examine functional connectivity in a fronto-cingulate network during performance on a Stroop task, and found increased connectivity between the DLPFC and ACC in OCD patients compared with healthy controls.”
From Response Inhibition and Interference Control in Obsessive–Compulsive Spectrum Disorders (2014) · cites this paper as Schlosser et al. (2010)
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Cites
Friston, K. J., Harrison, L., & Penny, W. (2003) · NeuroImage · doi:10.1016/s1053-8119(03)00202-7 · Cited by 4,583 · see citing works
MacDonald, A. W., Cohen, J. D., Stenger, V. A., & Carter, C. S. (2000) · Science · doi:10.1126/science.288.5472.1835 · Cited by 3,666 · see citing works
Conflict monitoring and anterior cingulate cortex: an update
Botvinick, M. M., Cohen, J. D., & Carter, C. S. (2004) · Trends in Cognitive Sciences · doi:10.1016/j.tics.2004.10.003 · Cited by 3,623 · see citing works
Contributions of anterior cingulate cortex to behaviour
Devinsky, O., Morrell, M. J., & Vogt, B. A. (1995) · Brain · doi:10.1093/brain/118.1.279 · Cited by 3,377 · see citing works
Anterior Cingulate Conflict Monitoring and Adjustments in Control
Kerns, J. G., Cohen, J. D., MacDonald, A. W., Cho, R. Y., Stenger, V. A., & Carter, C. S. (2004) · Science · doi:10.1126/science.1089910 · Cited by 2,891 · see citing works
Cohen, J. D., Dunbar, K. N., & McClelland, J. L. (1990) · Psychological Review · doi:10.1037/0033-295x.97.3.332 · Cited by 2,128 · see citing works
Bayesian model selection for group studies
Stephan, K. E., Penny, W. D., Daunizeau, J., Moran, R. J., & Friston, K. J. (2009) · NeuroImage · doi:10.1016/j.neuroimage.2009.03.025 · Cited by 1,423 · see citing works
Ridderinkhof, K. R., van den Wildenberg, W. P. M., Segalowitz, S. J., & Carter, C. S. (2004) · Brain and Cognition · doi:10.1016/j.bandc.2004.09.016 · Cited by 1,407 · see citing works
Etkin, A., Egner, T., Peraza, D. M., Kandel, E. R., & Hirsch, J. (2006) · Neuron · doi:10.1016/j.neuron.2006.07.029 · Cited by 1,360 · see citing works
Dysconnection in schizophrenia: from abnormal synaptic plasticity to failures of self-monitoring
Stephan, K. E., Friston, K. J., & Frith, C. D. (2009) · Schizophrenia Bulletin · doi:10.1093/schbul/sbn176 · Cited by 1,134 · see citing works
Dorsal anterior cingulate cortex: A role in reward-based decision making
Bush, G., Vogt, B. A., Holmes, J., Dale, A. M., Greve, D., Jenike, M. A., & Rosen, B. R. (2002) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.012470999 · Cited by 1,096 · see citing works
Egner, T., & Joy Hirsch, C. (2005) · Nature Neuroscience · doi:10.1038/nn1594 · Cited by 1,095 · see citing works
The dynamic brain: from spiking neurons to neural masses and cortical fields
Deco, G., Jirsa, V. K., Robinson, P. A., Breakspear, M., & Friston, K. (2008) · PLoS Computational Biology · doi:10.1371/journal.pcbi.1000092 · Cited by 1,084 · see citing works
Anterior cingulate cortex and conflict detection: an update of theory and data
Carter, C. S., & van Veen, V. (2007) · Cognitive, Affective, & Behavioral Neuroscience · doi:10.3758/cabn.7.4.367 · Cited by 1,056 · see citing works
Miezin, F. M., Maccotta, L., Ollinger, J., Petersen, S., & Buckner, R. (2000) · NeuroImage · doi:10.1006/nimg.2000.0568 · Cited by 1,033 · see citing works
Parsing executive processes: Strategic vs. evaluative functions of the anterior cingulate cortex
Carter, C. S., Macdonald, A. M., Botvinick, M., Ross, L. L., Stenger, V. A., Noll, D. C., & Cohen, J. D. (2000) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.97.4.1944 · Cited by 954 · see citing works
Prefrontal–cingulate interactions in action monitoring
Gehring, W. J., & Knight, R. T. (2000) · Nature Neuroscience · doi:10.1038/74899 · Cited by 912 · see citing works
Choice, uncertainty and value in prefrontal and cingulate cortex
Rushworth, M. F. S., & Behrens, T. E. J. (2008) · Nature Neuroscience · doi:10.1038/nn2066 · Cited by 866 · see citing works
Comparing dynamic causal models.
Penny, W. D., Stephan, K. E., Mechelli, A., & Friston, K. J. (2004) · NeuroImage · doi:10.1016/j.neuroimage.2004.03.026 · Cited by 848 · see citing works
Büchel, C. (1997) · Cerebral Cortex · doi:10.1093/cercor/7.8.768 · Cited by 794 · see citing works
Action-Monitoring Dysfunction in Obsessive-Compulsive Disorder
Gehring, W. J., Himle, J., & Nisenson, L. G. (2000) · Psychological Science · doi:10.1111/1467-9280.00206 · Cited by 670 · see citing works
The Binomial Distribution of Right, Mixed and Left Handedness
Annett, M. (1967) · Quarterly Journal of Experimental Psychology · doi:10.1080/14640746708400109 · Cited by 630 · see citing works
Motor Inhibition and Cognitive Flexibility in Obsessive-Compulsive Disorder and Trichotillomania
Chamberlain, S. R., Fineberg, N. A., Blackwell, A. D., Robbins, T. W., & Sahakian, B. J. (2006) · American Journal of Psychiatry · doi:10.1176/ajp.2006.163.7.1282 · Cited by 627 · see citing works
Conflict-induced behavioural adjustment: a clue to the executive functions of the prefrontal cortex
Mansouri, F. A., Tanaka, K., & Buckley, M. J. (2009) · Nature Reviews Neuroscience · doi:10.1038/nrn2538 · Cited by 559 · see citing works
Peterson, B. S., Skudlarski, P., Gatenby, J. C., Zhang, H., Anderson, A. W., & Gore, J. C. (1999) · Biological Psychiatry · doi:10.1016/s0006-3223(99)00056-6 · Cited by 530 · see citing works
Predictive codes for forthcoming perception in the frontal cortex.
Summerfield, C., Egner, T., Greene, M., Koechlin, E., Mangels, J., & Hirsch, J. (2006) · Science · doi:10.1126/science.1132028 · Cited by 496 · see citing works
Stuss, D. T., Floden, D., Alexander, M. P., Levine, B., & Katz, D. (2001) · Neuropsychologia · doi:10.1016/s0028-3932(01)00013-6 · Cited by 464 · see citing works
Paus, T., Koski, L. M., Caramanos, Z., & Westbury, C. F. (1998) · Neuroreport · doi:10.1097/00001756-199806220-00001 · Cited by 462 · see citing works
An Event-related Functional MRI Study of the Stroop Color Word Interference Task
Leung, H. (2000) · Cerebral Cortex · doi:10.1093/cercor/10.6.552 · Cited by 448 · see citing works
Anterior cingulate and prefrontal cortex: who's in control?
Cohen, J. D., Botvinick, M., & Carter, C. S. (2000) · Nature Neuroscience · doi:10.1038/74783 · Cited by 436 · see citing works
Frontal-striatal dysfunction during planning in obsessive-compulsive disorder
van den Heuvel, O. A., Veltman, D. J., Groenewegen, H. J., Cath, D. C., van Balkom, A. J. L. M., van Hartskamp, J., Barkhof, F., & van Dyck, R. (2005) · Archives of General Psychiatry · doi:10.1001/archpsyc.62.3.301 · Cited by 417 · see citing works
Reduced orbitofrontal-striatal activity on a reversal learning task in obsessive-compulsive disorder
Remijnse, P. L., Nielen, M. M. A., van Balkom, A. J. L. M., Cath, D. C., van Oppen, P., Uylings, H. B. M., & Veltman, D. J. (2006) · Archives of General Psychiatry · doi:10.1001/archpsyc.63.11.1225 · Cited by 408 · see citing works
Color-Word Matching Stroop Task: Separating Interference and Response Conflict
Zysset, S., Müller, K., Lohmann, G., & von Cramon, D. Y. (2001) · NeuroImage · doi:10.1006/nimg.2000.0665 · Cited by 386 · see citing works
Error-related hyperactivity of the anterior cingulate cortex in obsessive-compulsive disorder
Fitzgerald, K. D., Welsh, R. C., Gehring, W. J., Abelson, J. L., Himle, J. A., Liberzon, I., & Taylor, S. F. (2005) · Biological Psychiatry · doi:10.1016/j.biopsych.2004.10.038 · Cited by 378 · see citing works
Ursu, S., Stenger, V. A., Shear, M. K., Jones, M. R., & Carter, C. S. (2003) · Psychological Science · doi:10.1111/1467-9280.24411 · Cited by 341 · see citing works
Kerns, J. G., Cohen, J. D., MacDonald, A. W., Johnson, M. K., Stenger, V. A., Aizenstein, H., & Carter, C. S. (2005) · American Journal of Psychiatry · doi:10.1176/appi.ajp.162.10.1833 · Cited by 336 · see citing works
Maltby, N., Tolin, D. F., Worhunsky, P., O'Keefe, T. M., & Kiehl, K. A. (2005) · NeuroImage · doi:10.1016/j.neuroimage.2004.08.041 · Cited by 331 · see citing works
Error-related brain activity in obsessive-compulsive undergraduates
Hajcak, G., & Simons, R. F. (2002) · Psychiatry Research · doi:10.1016/s0165-1781(02)00034-3 · Cited by 326 · see citing works
Modelling functional integration: a comparison of structural equation and dynamic causal models
Penny, W. D., Stephan, K. E., Mechelli, A., & Friston, K. J. (2004) · NeuroImage · doi:10.1016/j.neuroimage.2004.07.041 · Cited by 325 · see citing works
Milham, M. P., Banich, M. T., Claus, E. D., & Cohen, N. J. (2003) · NeuroImage · doi:10.1016/s1053-8119(02)00050-2 · Cited by 321 · see citing works
Neural correlates of cognitive inflexibility during task-switching in obsessive-compulsive disorder
Gu, B.-M., Park, J.-Y., Kang, D.-H., Lee, S. J., Yoo, S. Y., Jo, H. J., Choi, C.-H., Lee, J.-M., & Kwon, J. S. (2007) · Brain · doi:10.1093/brain/awm277 · Cited by 284 · see citing works
Wagner, G., Sinsel, E., Sobanski, T., Köhler, S., Marinou, V., Mentzel, H.-J., Sauer, H., & Schlösser, R. G. M. (2006) · Biological Psychiatry · doi:10.1016/j.biopsych.2005.10.025 · Cited by 278 · see citing works
Self-citationSchlösser, R. G. M., Gesierich, T., Kaufmann, B., Vučurević, G., Hunsche, S., Gawehn, J., & Stoeter, P. (2003) · NeuroImage · doi:10.1016/s1053-8119(03)00106-x · Cited by 254 · see citing works
Self-citationBrain regions underlying response inhibition and interference monitoring and suppression
Blasi, G., Goldberg, T. E., Weickert, T., Das, S., Kohn, P., Zoltick, B., Bertolino, A., Callicott, J. H., Weinberger, D. R., & Mattay, V. S. (2006) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2006.04680.x · Cited by 240 · see citing works
Kondo, H., Osaka, N., & Osaka, M. (2004) · NeuroImage · doi:10.1016/j.neuroimage.2004.06.014 · Cited by 227 · see citing works
Human Anterior Cingulate Cortex Neurons Encode Cognitive and Emotional Demands
Davis, K. D., Taylor, K. S., Hutchison, W. D., Dostrovsky, J. O., McAndrews, M. P., Richter, E. O., & Lozano, A. M. (2005) · Journal of Neuroscience · doi:10.1523/jneurosci.2315-05.2005 · Cited by 200 · see citing works
Adaptive decision making and value in the anterior cingulate cortex
Walton, M. E., Croxson, P. L., Behrens, T. E. J., Kennerley, S. W., & Rushworth, M. F. S. (2007) · NeuroImage · doi:10.1016/j.neuroimage.2007.03.029 · Cited by 182 · see citing works
Learning-related Neuronal Responses in Prefrontal Cortex Studied with Functional Neuroimaging
Fletcher, P. C. (1999) · Cerebral Cortex · doi:10.1093/cercor/9.2.168 · Cited by 177 · see citing works
Neural basis of the Stroop interference task: Response competition or selective attention?
Mead, L. A., Mayer, A. R., Bobholz, J. A., Woodley, S. J., Cunningham, J. M., Hammeke, T. A., & Rao, S. M. (2002) · Journal of the International Neuropsychological Society · doi:10.1017/s1355617702860015 · Cited by 153 · see citing works
Schlösser, R. G. M., Wagner, G., Koch, K., Dahnke, R., Reichenbach, J. R., & Sauer, H. (2008) · NeuroImage · doi:10.1016/j.neuroimage.2008.08.002 · Cited by 148 · see citing works
Self-citationMedalla, M., & Barbas, H. (2009) · Neuron · doi:10.1016/j.neuron.2009.01.006 · Cited by 146 · see citing works
A Dynamic Causal Modeling Study on Category Effects: Bottom–Up or Top–Down Mediation?
Mechelli, A., Price, C. J., Noppeney, U., & Friston, K. J. (2003) · Journal of Cognitive Neuroscience · doi:10.1162/089892903770007317 · Cited by 146 · see citing works
Banich, M. T., Milham, M. P., Jacobson, B. L., WEBB, A. G., Wszalek, T., Cohen, N. J., & Kramer, A. F. (2001) · Progress in brain research · doi:10.1016/s0079-6123(01)34030-x · Cited by 131 · see citing works
Yoon, U., Lee, J., Im, K., Shin, Y., Cho, B. H., Kim, I. Y., Kwon, J. S., & Kim, S. I. (2007) · NeuroImage · doi:10.1016/j.neuroimage.2006.11.021 · Cited by 101 · see citing works
Schlösser, R. G. M., Wagner, G., & Sauer, H. (2005) · Neuroscience · doi:10.1016/j.neuroscience.2005.06.037 · Cited by 99 · see citing works
Self-citationDecision making, performance and outcome monitoring in frontal cortical areas
Ullsperger, M., & von Cramon, D. Y. (2004) · Nature Neuroscience · doi:10.1038/nn1104-1173 · Cited by 67 · see citing works
Erickson, K. I., Milham, M. P., Colcombe, S. J., Kramer, A. F., Banich, M. T., WEBB, A. G., & Cohen, N. J. (2003) · Human Brain Mapping · doi:10.1002/hbm.10158 · Cited by 61 · see citing works
Parkinson's syndrome after closed head injury: a single case report
Doder, M., Jahanshahi, M., Turjanski, N., MOSELEY, I. F., & Lees, A. J. (1999) · Journal of Neurology Neurosurgery & Psychiatry · doi:10.1136/jnnp.66.3.380 · Cited by 51 · see citing works
Mallet, L., Mazoyer, B. M., & Martinot, J. (1998) · Psychiatry Research Neuroimaging · doi:10.1016/s0925-4927(98)00011-0 · Cited by 49 · see citing works
Assessing the State Space of the Brain with fMRI: An Integrative View of Current Methods
Schlösser, R. G. M., Koch, K., & Wagner, G. (2007) · Pharmacopsychiatry · doi:10.1055/s-2007-992769 · Cited by 8 · see citing works
Self-citation
Flagged first, then by citations
Cited by
Sorted by citations
Obsessive-compulsive disorder: beyond segregated cortico-striatal pathways
Milad, M. R., & Rauch, S. L. (2012) · Trends in Cognitive Sciences · doi:10.1016/j.tics.2011.11.003 · Cited by 847 · see citing works
The neuropsychology of adult obsessive–compulsive disorder: A meta-analysis
Abramovitch, A., Abramowitz, J. S., & Mittelman, A. (2013) · Clinical Psychology Review · doi:10.1016/j.cpr.2013.09.004 · Cited by 444 · see citing works
Affective Cognition and its Disruption in Mood Disorders
Elliott, R., Zahn, R., Deakin, J. F. W., & Anderson, I. M. (2011) · Neuropsychopharmacology · doi:10.1038/npp.2010.77 · Cited by 330 · see citing works
Differential neural responses to food images in women with bulimia versus anorexia nervosa
Brooks, S. J., O′Daly, O. G., Uher, R., Friederich, H.-C., Giampietro, V., Brammer, M., Williams, S. C. R., Schiöth, H. B., Treasure, J., & Campbell, I. C. (2011) · PLoS ONE · doi:10.1371/journal.pone.0022259 · Cited by 231 · see citing works
Norman, L. J., Taylor, S. F., Liu, Y., Radua, J., Chye, Y., De Wit, S. J., Huyser, C., Karahanoglu, F. I., Luks, T., Manoach, D., et al. (2019) · Biological Psychiatry · doi:10.1016/j.biopsych.2018.11.010 · Cited by 189 · see citing works
Carlisi, C. O., Norman, L. J., Lukito, S. S., Radua, J., Mataix-Cols, D., & Rubia, K. (2017) · Biological Psychiatry · doi:10.1016/j.biopsych.2016.10.006 · Cited by 176 · see citing works
Response Inhibition and Interference Control in Obsessive–Compulsive Spectrum Disorders
van Velzen, L. S., Vriend, C., de Wit, S. J., & van den Heuvel, O. A. (2014) · Frontiers in Human Neuroscience · doi:10.3389/fnhum.2014.00419 · Cited by 159 · see citing works
Banca, P., Voon, V., Vestergaard, M. D., Philipiak, G., Almeida, I., Pocinho, F., Relvas, J., & Castelo-Branco, M. (2015) · Brain · doi:10.1093/brain/awu379 · Cited by 148 · see citing works
Eng, G. K., Sim, K., & Chen, S.-H. A. (2015) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2015.03.002 · Cited by 148 · see citing works
Bourne, S. K., Eckhardt, C. A., Sheth, S. A., & Eskandar, E. N. (2012) · Frontiers in Integrative Neuroscience · doi:10.3389/fnint.2012.00029 · Cited by 146 · see citing works
McGovern, R. A., & Sheth, S. A. (2017) · Journal of Neurosurgery · doi:10.3171/2016.1.jns15601 · Cited by 117 · see citing works
Cheng, Y., Xu, J., Nie, B., Luo, C., Yang, T., Li, H., Lu, J., Xu, L., Shan, B., & Xu, X. (2013) · PLoS ONE · doi:10.1371/journal.pone.0067478 · Cited by 82 · see citing works
Göttlich, M., Krämer, U. M., Kordon, A., Hohagen, F., & Zurowski, B. (2015) · Biological Psychology · doi:10.1016/j.biopsycho.2015.09.004 · Cited by 73 · see citing works
Del Casale, A., Rapinesi, C., Kotzalidis, G. D., De Rossi, P., Curto, M., Janiri, D., Criscuolo, S., Alessi, M. C., Ferri, V. R., De Giorgi, R., et al. (2016) · The World Journal of Biological Psychiatry · doi:10.3109/15622975.2015.1102323 · Cited by 63 · see citing works
Decision-making impairment in obsessive-compulsive disorder as measured by the Iowa Gambling Task
Rocha, F. F. D., Alvarenga, N. B., Malloy-Diniz, L., & Corrêa, H. (2011) · Arquivos de Neuro-Psiquiatria · doi:10.1590/s0004-282x2011000500013 · Cited by 59 · see citing works
Rotge, J. Y., Aouizerate, B., Amestoy, V, Lambrecq, V, Langbour, N., Nguyen, T. H., Dovero, S., Cardoit, L., Tignol, J., Bioulac, B., et al. (2012) · Translational Psychiatry · doi:10.1038/tp.2012.88 · Cited by 58 · see citing works
Altered inhibition-related frontolimbic connectivity in obsessive–compulsive disorder
van Velzen, L. S., de Wit, S. J., Ćurĉić‐Blake, B., Cath, D. C., de Vries, F. E., Veltman, D. J., van der Werf, Y. D., & van den Heuvel, O. A. (2015) · Human Brain Mapping · doi:10.1002/hbm.22898 · Cited by 50 · see citing works
Koch, K., Wagner, G., Schachtzabel, C., Peikert, G., Schultz, C. C., Sauer, H., & Schlösser, R. G. (2012) · Neuropsychologia · doi:10.1016/j.neuropsychologia.2012.02.002 · Cited by 45 · see citing works
Self-citationPerera, M. P. N., Gotsis, E. S., Bailey, N. W., Fitzgibbon, B. M., & Fitzgerald, P. B. (2024) · Cerebral Cortex · doi:10.1093/cercor/bhae327 · Cited by 34 · see citing works
da Rocha, F. F., Malloy-Diniz, L., Lage, N. V., & Corrêa, H. (2011) · Genes, Brain and Behavior · doi:10.1111/j.1601-183x.2011.00687.x · Cited by 32 · see citing works
Zhu, C., Yu, F., Ye, R., Chen, X., Dong, Y., Li, D., Zhang, L., Li, D., & Wang, K. (2014) · PLoS ONE · doi:10.1371/journal.pone.0090874 · Cited by 22 · see citing works
Neuromodulation for obsessive-compulsive disorder
Aronson, J. P., Katnani, H. A., & Eskandar, E. N. (2014) · Neurosurgery Clinics of North America · doi:10.1016/j.nec.2013.08.003 · Cited by 18 · see citing works
Olson, C. A., Hale, L. R., Hamilton, N., Powell, J. N., Martin, L. E., & Savage, C. R. (2016) · Behavioural Brain Research · doi:10.1016/j.bbr.2015.08.031 · Cited by 17 · see citing works
Funch Uhre, V., Melissa Larsen, K., Marc Herz, D., Baaré, W., Katrine Pagsberg, A., & Roman Siebner, H. (2022) · NeuroImage: Clinical · doi:10.1016/j.nicl.2022.103268 · Cited by 18 · see citing works
A closer look to neural pathways and psychopharmacology of obsessive compulsive disorder
Gargano, S. P., Santos, M. G., Taylor, S. M., & Pastis, I. (2023) · Frontiers in Behavioral Neuroscience · doi:10.3389/fnbeh.2023.1282246 · Cited by 18 · see citing works
Pena Garijo, J., Barros Loscertales, A., Ventura Campos, N., Ruipérez Rodríguez, M. Á., Edo Villamón, S., & Ávila Rivera, C. (2011) · Revista de Neurología · doi:10.33588/rn.5302.2010767 · Cited by 12 · see citing works
Liu, Q., Tan, B., Zhou, J., Zheng, Z., Li, L., & Yang, Y. (2017) · Medicine · doi:10.1097/md.0000000000005655 · Cited by 9 · see citing works
Li, Z., Tong, G., Wang, Y., Ruan, H., Zheng, Z., Cheng, J., & Wang, Z. (2024) · The World Journal of Biological Psychiatry · doi:10.1080/15622975.2023.2251057 · Cited by 4 · see citing works
Neural mechanisms underlying cognitive inflexibility in obsessive-compulsive disorder: a review
Guo, W., Neo, P. S.-H., & McNaughton, N. (2026) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2026.1795436
- Authors
- Schlösser, R. G. M., Wagner, G., Schachtzabel, C., Peikert, G., Koch, K., Reichenbach, J. R., & Sauer, H.
- Affiliations
- Friedrich Schiller University Jena (DE)
- Corresponding author
- Schlösser, Ralf G.M.
- Venue
- Human Brain Mapping
- Publisher
- Wiley
- Published
- 2010-11-16
- Volume
- 31
- Issue
- 12
- Pages
- 1834-1850
- ISSN
- 1065-9471 (ISSN-L)
- 1097-0193
- PMC
- PMC6871164
- OpenAlex
- W2167373053
- Cited by
- 111
- References
- 60
- Citations by year
- 2026: 5 · 2025: 2 · 2024: 3 · 2023: 4 · 2022: 3 · 2021: 7 · 2020: 6 · 2019: 6 · 2018: 8 · 2017: 4 · 2016: 8 · 2015: 8 · 2014: 13 · 2013: 12 · 2012: 11
- FWCI
- 11.91
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Human Brain Mapping (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Friedrich-Schiller-Universität Jena
- Bundesministerium für Bildung und Forschung (AQ4 FKZ01ZZ0405, 01GW0740)
- Topics
- Social Sciences › Psychology › Clinical Psychology › Obsessive-Compulsive Spectrum Disorders
- Life Sciences › Neuroscience › Cognitive Neuroscience › Neural and Behavioral Psychology Studies
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Keywords
- obsessive-compulsive disorder, effective connectivity, error control, dorsal anterior cingulate cortex, dorsolateral prefrontal cortex, dynamic causal modeling, Stroop task, decision-making
- MeSH terms
- Adult, Brain Mapping, Cognition Disorders, Female, Gyrus Cinguli, Humans, Magnetic Resonance Imaging, Male, Models, Neurological, Obsessive-Compulsive Disorder, Prefrontal Cortex
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
