Activation of v-Myb avian myeloblastosis viral oncogene homolog-like2 (MYBL2)-LIN9 complex contributes to human hepatocarcinogenesis and identifies a subset of hepatocellular carcinoma with mutant p53

Requirement for p53 and p21 to Sustain G ₂ Arrest After DNA Damage

Bunz, F., Dutriaux, A., Lengauer, C., Waldman, T., Zhou, S., Brown, J. P., Sedivy, J. M., Kinzler, K. W., & Vogelstein, B. (1998) · Science · doi:10.1126/science.282.5393.1497 · Cited by 2,803 · see citing works

Primary liver cancer: Worldwide incidence and trends

Bosch, F. X., Ribes, J., Díaz, M., & Clèries, R. (2004) · Gastroenterology · doi:10.1053/j.gastro.2004.09.011 · Cited by 2,473 · see citing works

Molecular targeted therapies in hepatocellular carcinoma†

Llovet, J. M., & Bruix, J. (2008) · Hepatology · doi:10.1002/hep.22506 · Cited by 999 · see citing works

Classification and prediction of survival in hepatocellular carcinoma by gene expression profiling

Lee, J., Chu, I., Heo, J., Calvisi, D. F., Sun, Z., Roskams, T., Durnez, A., Demetris, A. J., & Thorgeirsson, S. S. (2004) · Hepatology · doi:10.1002/hep.20375 · Cited by 922 · see citing works

Cellular Targets for Activation by the E2F1 Transcription Factor Include DNA Synthesis- and G 1 /S-Regulatory Genes

DeGregori, J. V., Kowalik, T. F., & Nevins, J. R. (1995) · Molecular and Cellular Biology · doi:10.1128/mcb.15.8.4215 · Cited by 918 · see citing works

MYB function in normal and cancer cells

Ramsay, R. G., & Gonda, T. J. (2008) · Nature reviews. Cancer · doi:10.1038/nrc2439 · Cited by 619 · see citing works

p53: traffic cop at the crossroads of DNA repair and recombination

Sengupta, S., & Harris, C. C. (2005) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm1546 · Cited by 544 · see citing works

p53: 25 years after its discovery

Hofseth, L. J., Hussain, S. P., & Harris, C. C. (2004) · Trends in Pharmacological Sciences · doi:10.1016/j.tips.2004.02.009 · Cited by 431 · see citing works

E2Fs link the control of G1/S and G2/M transcription

Zhu, W., Giangrande, P. H., & Nevins, J. R. (2004) · The EMBO Journal · doi:10.1038/sj.emboj.7600459 · Cited by 320 · see citing works

Frequent amplification of chromosomal region 20q12-q13 in ovarian cancer.

Tanner, M., Grénman, S., Koul, A., Johannsson, O. T., Meltzer, P. S., Pejovic, T. B., Borg, Å., & Isola, J. J. (2000) · PubMed · Cited by 317 · see citing works

Comparative genomic hybridization analysis of 38 breast cancer cell lines: a basis for interpreting complementary DNA microarray data.

Forozan, F., Mahlamäki, E., Monni, O. M., Chen, Y., Veldman, R., Jiang, Y. Y., Gooden, G. C., Ethier, S. P., Kallioniemi, A. H., & Kallioniemi, O. (2000) · PubMed · Cited by 278 · see citing works

Alterations of RB1, p53 and Wnt pathways in hepatocellular carcinomas associated with hepatitis C, hepatitis B and alcoholic liver cirrhosis

Edamoto, Y., Hara, A., Biernat, W., Terracciano, L., Cathomas, G., Riehle, H., Matsuda, M., Fujii, H., Scoazec, J., & Ohgaki, H. (2003) · International Journal of Cancer · doi:10.1002/ijc.11254 · Cited by 220 · see citing works

Amplification and overexpression of JUNB is associated with primary cutaneous T-cell lymphomas

Mao, X., Orchard, G. E., Lillington, D. M., Russell‐Jones, R., Young, B. D., & Whittaker, S. J. (2003) · Blood · doi:10.1182/blood-2002-08-2434 · Cited by 193 · see citing works

LINC, a Human Complex That is Related to pRB-Containing Complexes in Invertebrates Regulates the Expression of G₂/M Genes

Schmit, F., Korenjak, M., Mannefeld, M., Schmitt, K., Franke, C., von Eyss, B., Gagrica, S., Hanel, F., Brehm, A., & Gaubatz, S. (2007) · Cell Cycle · doi:10.4161/cc.6.15.4512 · Cited by 179 · see citing works

Dual-Specificity Phosphatase 1 Ubiquitination in Extracellular Signal-Regulated Kinase–Mediated Control of Growth in Human Hepatocellular Carcinoma

Calvisi, D. F., Pinna, F., Meloni, F., Ladu, S., Pellegrino, R., Sini, M., Daino, L., Simile, M. M., Miglio, M. R. D., Virdis, P., et al. (2008) · Cancer Research · doi:10.1158/0008-5472.can-07-6157 · Cited by 127 · see citing works

Genetics of hepatocellular carcinoma

Teufel, A. (2007) · World Journal of Gastroenterology · doi:10.3748/wjg.v13.i16.2271 · Cited by 126 · see citing works

The human synMuv‐like protein LIN‐9 is required for transcription of G2/M genes and for entry into mitosis

Osterloh, L., von Eyß, B., Schmit, F., Rein, L., Hübner, D., Samans, B., Hauser, S., & Gaubatz, S. (2006) · The EMBO Journal · doi:10.1038/sj.emboj.7601478 · Cited by 122 · see citing works

SKP2 and CKS1 Promote Degradation of Cell Cycle Regulators and Are Associated With Hepatocellular Carcinoma Prognosis

Calvisi, D. F., Ladu, S., Pinna, F., Frau, M., Tomasi, M. L., Sini, M., Simile, M. M., Bonelli, P., Muroni, M. R., Seddaiu, M. A., et al. (2009) · Gastroenterology · doi:10.1053/j.gastro.2009.08.005 · Cited by 121 · see citing works

Mammalian Mip/LIN-9 interacts with either the p107, p130/E2F4 repressor complex or B-Myb in a cell cycle-phase-dependent context distinct from the Drosophila dREAM complex

Pilkinton, M. A., Sandoval, R., & Colamonici, O. R. (2007) · Oncogene · doi:10.1038/sj.onc.1210562 · Cited by 111 · see citing works

p130/E2F4 Binds to and Represses the cdc2 Promoter in Response to p53

Taylor, W. R., Schönthal, A. H., Galante, J., & Stark, G. R. (2001) · Journal of Biological Chemistry · doi:10.1074/jbc.m005101200 · Cited by 110 · see citing works

Disruption of β-catenin pathway or genomic instability define two distinct categories of liver cancer in transgenic mice

Calvisi, D. F., Factor, V. M., Ladu, S., Conner, E. A., & Thorgeirsson, S. S. (2004) · Gastroenterology · doi:10.1053/j.gastro.2004.02.014 · Cited by 100 · see citing works

A Lin-9 complex is recruited by B-Myb to activate transcription of G2/M genes in undifferentiated embryonal carcinoma cells

Knight, A. S., Notaridou, M., & Watson, R. J. (2009) · Oncogene · doi:10.1038/onc.2009.22 · Cited by 89 · see citing works

Role of HSP90, CDC37, and CRM1 as modulators of P16INK4A activity in rat liver carcinogenesis and human liver cancer†

Pascale, R. M., Simile, M. M., Calvisi, D. F., Frau, M., Muroni, M. R., Seddaiu, M. A., Daino, L., Muntoni, M. D., Miglio, M. R. D., Thorgeirsson, S. S., et al. (2005) · Hepatology · doi:10.1002/hep.20962 · Cited by 87 · see citing works

Forkhead box M1B is a determinant of rat susceptibility to hepatocarcinogenesis and sustains ERK activity in human HCC

Calvisi, D. F., Pinna, F., Ladu, S., Pellegrino, R., Simile, M. M., Frau, M., Miglio, M. R. D., Tomasi, M. L., Sanna, V., Muroni, M. R., et al. (2009) · Gut · doi:10.1136/gut.2008.152652 · Cited by 87 · see citing works

B-MYB Is Required for Recovery from the DNA Damage–Induced G2 Checkpoint in p53 Mutant Cells

Mannefeld, M., Klassen, E., & Gaubatz, S. (2009) · Cancer Research · doi:10.1158/0008-5472.can-08-4156 · Cited by 82 · see citing works

Degradation of B-Myb by ubiquitin-mediated proteolysis: involvement of the Cdc34-SCFp45Skp2 pathway

Charrasse, S., Carena, I., Brondani, V., Klempnauer, K.-H., & Ferrari, S. M. (2000) · Oncogene · doi:10.1038/sj.onc.1203618 · Cited by 79 · see citing works

Prognostic markers and putative therapeutic targets for hepatocellular carcinoma

Frau, M., Biasi, F., Feo, F., & Pascale, R. M. (2010) · Molecular Aspects of Medicine · doi:10.1016/j.mam.2010.02.007 · Cited by 78 · see citing works

The effect of environmental cues on the differentiation of myofibroblasts in peritoneal granulation tissue

(2000) · doi:10.1002/1096-9896(2000)9999:9999 · Cited by 70 · see citing works

E2F Mediates Sustained G2 Arrest and Down-regulation of Stathmin and AIM-1 Expression in Response to Genotoxic Stress

Polager, S., & Ginsberg, D. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m210327200 · Cited by 70 · see citing works

Detection of somatic DNA alterations in azoxymethane-induced F344 rat colon tumors by random amplified polymorphic DNA analysis

Luceri, C., Filippo, C. D., Caderni, G., Gambacciani, L., Salvadori, M., Giannini, A., & Dolara, P. (2000) · Carcinogenesis · doi:10.1093/carcin/21.9.1753 · Cited by 68 · see citing works

Loss of heterozygosity and analysis of mutation of p53 in hepatocellular carcinoma

Yumoto, Y., Hanafusa, T., Hada, H., Morita, T., Ooguchi, S., Shinji, N., Mitani, T., Hamaya, K., Koide, N., & Tsuji, T. (1995) · Journal of Gastroenterology and Hepatology · doi:10.1111/j.1440-1746.1995.tb01075.x · Cited by 65 · see citing works

NORE1A Tumor Suppressor Candidate Modulates p21CIP1 via p53

Calvisi, D. F., Donninger, H., Vos, M. D., Birrer, M. J., Gordon, L. E., Leaner, V. D., & Clark, G. J. (2009) · Cancer Research · doi:10.1158/0008-5472.can-08-3672 · Cited by 64 · see citing works

Activation of B‐Myb by E2F1 in hepatocellular carcinoma

Nakajima, T., Yasui, K., Zen, K., Inagaki, Y., Fujii, H., Minami, M., Tanaka, S., Taniwaki, M., Itoh, Y., Arii, S., et al. (2008) · Hepatology Research · doi:10.1111/j.1872-034x.2008.00324.x · Cited by 64 · see citing works

Mybl2 expression is under genetic control and contributes to determine a hepatocellular carcinoma susceptible phenotype

Frau, M., Ladu, S., Calvisi, D. F., Simile, M. M., Bonelli, P., Daino, L., Tomasi, M. L., Seddaiu, M. A., Feo, F., & Pascale, R. M. (2011) · Journal of Hepatology · doi:10.1016/j.jhep.2010.10.031 · Cited by 60 · see citing works

Aberrant iNOS signaling is under genetic control in rodent liver cancer and potentially prognostic for the human disease

Calvisi, D. F., Pinna, F., Ladu, S., Pellegrino, R., Muroni, M. R., Simile, M. M., Frau, M., Tomasi, M. L., Miglio, M. R. D., Seddaiu, M. A., et al. (2008) · Carcinogenesis · doi:10.1093/carcin/bgn155 · Cited by 58 · see citing works

Dissection of Signal Transduction Pathways as a Tool for the Development of Targeted Therapies of Hepatocellular Carcinoma

Calvisi, D. F., Pascale, R. M., & Feo, F. (2007) · Reviews on Recent Clinical Trials · doi:10.2174/157488707781662715 · Cited by 49 · see citing works

Disruption of B-myb in DT40 cells reveals novel function for B-Myb in the response to DNA-damage

Ahlbory-Dieker, D. L., Appl, H., Lang, D., & Klempnauer, K. (2005) · Oncogene · doi:10.1038/sj.onc.1208869 · Cited by 24 · see citing works

Evidence for another tumor suppressor gene at 17p13.3 distal to TP53 in hepatocellular carcinoma

Guan, X., Sham, J. S. T., Tai, L.-S., Fang, Y., Li, H., & Liang, Q. (2003) · Cancer Genetics and Cytogenetics · doi:10.1016/s0165-4608(02)00654-4 · Cited by 22 · see citing works

Census and evaluation of p53 target genes

Fischer, M. (2017) · Oncogene · doi:10.1038/onc.2016.502 · Cited by 971 · see citing works

MYBL2 (B-Myb): a central regulator of cell proliferation, cell survival and differentiation involved in tumorigenesis

Musa, J., Aynaud, M.-M., Mirabeau, O., Delattre, O., & Grünewald, T. G. P. (2017) · Cell Death and Disease · doi:10.1038/cddis.2017.244 · Cited by 315 · see citing works

The p53-p21-DREAM-CDE/CHR pathway regulates G 2 /M cell cycle genes

Fischer, M., Quaas, M., Steiner, L., & Engeland, K. (2015) · Nucleic Acids Research · doi:10.1093/nar/gkv927 · Cited by 324 · see citing works

Cell cycle transcription control: DREAM/MuvB and RB-E2F complexes.

Fischer, M., & Müller, G. A. (2017) · Critical Reviews in Biochemistry and Molecular Biology · doi:10.1080/10409238.2017.1360836 · Cited by 255 · see citing works

The Transcription Factor FOXM1 (Forkhead box M1)

Wierstra, I. (2013) · Advances in cancer research · doi:10.1016/b978-0-12-407173-5.00004-2 · Cited by 174 · see citing works

MYB oncoproteins: emerging players and potential therapeutic targets in human cancer

Cicirò, Y., & Sala, A. (2021) · Oncogenesis · doi:10.1038/s41389-021-00309-y · Cited by 173 · see citing works

Role of transcriptional and posttranscriptional regulation of methionine adenosyltransferases in liver cancer progression

Frau, M., Tomasi, M. L., Simile, M. M., Demartis, M. I., Salis, F., Latte, G., Calvisi, D. F., Seddaiu, M. A., Daino, L., Feo, C. F., et al. (2012) · Hepatology · doi:10.1002/hep.25643 · Cited by 87 · see citing works

Identification of cyclin B1 and Sec62 as biomarkers for recurrence in patients with HBV-related hepatocellular carcinoma after surgical resection

Weng, L., Du, J., Zhou, Q.-H., Cheng, B., Li, J., Zhang, D., & Ling, C. (2012) · Molecular Cancer · doi:10.1186/1476-4598-11-39 · Cited by 86 · see citing works

Demethylzeylasteral inhibits glioma growth by regulating the miR-30e-5p/MYBL2 axis

Zhang, K., Fu, G., Pan, G., Li, C., Shen, L., Hu, R., Zhu, S., Chen, Y., & Cui, H. (2018) · Cell Death and Disease · doi:10.1038/s41419-018-1086-8 · Cited by 79 · see citing works

RB, p130 and p107 differentially repress G1/S and G2/M genes after p53 activation

Schade, A. E., Fischer, M., & DeCaprio, J. A. (2019) · Nucleic Acids Research · doi:10.1093/nar/gkz961 · Cited by 74 · see citing works

YAP-dependent induction of UHMK1 supports nuclear enrichment of the oncogene MYBL2 and proliferation in liver cancer cells

Wei, T., Weiler, S. M. E., Tóth, M., Sticht, C., Lutz, T., Thomann, S., Torre, C. D. L., Straub, B. K., Merker, S., Ruppert, T., et al. (2019) · Oncogene · doi:10.1038/s41388-019-0801-y · Cited by 76 · see citing works

p53 and Cell Cycle Dependent Transcription of kinesin family member 23 (KIF23) Is Controlled Via a CHR Promoter Element Bound by DREAM and MMB Complexes

Fischer, M., Grundke, I., Sohr, S., Quaas, M., Hoffmann, S., Knörck, A., Gumhold, C., & Rother, K. (2013) · PLoS ONE · doi:10.1371/journal.pone.0063187 · Cited by 64 · see citing works

MYBL2 is an independent prognostic marker that has tumor-promoting functions in colorectal cancer.

Ren, F., Wang, L., Shen, X., Xiao, X., Liu, Z., Wei, P., Wang, Y., Qi, P., Shen, C., Sheng, W., et al. (2015) · Europe PMC (PubMed Central) · Cited by 64 · see citing works

Indirect p53-dependent transcriptional repression of Survivin, CDC25C, and PLK1 genes requires the cyclin-dependent kinase inhibitor p21/CDKN1A and CDE/CHR promoter sites binding the DREAM complex

Fischer, M., Quaas, M., Nickel, A., & Engeland, K. (2015) · Oncotarget · doi:10.18632/oncotarget.6356 · Cited by 59 · see citing works

B-Myb Is Up-Regulated and Promotes Cell Growth and Motility in Non-Small Cell Lung Cancer

Jin, Y., Zhu, H., Cai, W. L., Fan, X., Wang, Y., Niu, Y., Song, F., & Bu, Y. (2017) · International Journal of Molecular Sciences · doi:10.3390/ijms18060860 · Cited by 58 · see citing works

Downregulation of miR-410 targeting the cyclin B1 gene plays a role in pituitary gonadotroph tumors

Müssnich, P., Raverot, G., Jaffrain‐Rea, M., Fraggetta, F., Wierinckx, A., Trouillas, J., Fusco, A., & D’Angelo, D. (2015) · Cell Cycle · doi:10.1080/15384101.2015.1064207 · Cited by 56 · see citing works

Histone acetyltransferase PCAF Up-regulated cell apoptosis in hepatocellular carcinoma via acetylating histone H4 and inactivating AKT signaling

Zheng, X. M., Gai, X., Ding, F., Lu, Z., Tu, K., Yao, Y., & Liu, Q. (2013) · Molecular Cancer · doi:10.1186/1476-4598-12-96 · Cited by 54 · see citing works

A MYBL2 complex for RRM2 transactivation and the synthetic effect of MYBL2 knockdown with WEE1 inhibition against colorectal cancer

Liu, Q., Guo, L., Qi, H., Lou, M., Wang, R., Hai, B., Xu, K., Zhu, L., Ding, Y., Li, C., et al. (2021) · Cell Death and Disease · doi:10.1038/s41419-021-03969-1 · Cited by 46 · see citing works

High MYBL2 expression and transcription regulatory activity is associated with poor overall survival in patients with hepatocellular carcinoma

Guan, Z., Cheng, W., Huang, D., & Wei, A. (2017) · Current Research in Translational Medicine · doi:10.1016/j.retram.2017.11.002 · Cited by 43 · see citing works

An expression signature of phenotypic resistance to hepatocellular carcinoma identified by cross-species gene expression analysis

Frau, M., Simile, M. M., Tomasi, M. L., Demartis, M. I., Daino, L., Seddaiu, M. A., Brozzetti, S., Feo, C. F., Massarelli, G., Solinas, G., et al. (2012) · Cellular Oncology · doi:10.1007/s13402-011-0067-z · Cited by 42 · see citing works

Deregulation of signalling pathways in prognostic subtypes of hepatocellular carcinoma: Novel insights from interspecies comparison

Calvisi, D. F., Frau, M., Tomasi, M. L., Feo, F., & Pascale, R. M. (2012) · Biochimica et Biophysica Acta (BBA) - Reviews on Cancer · doi:10.1016/j.bbcan.2012.04.003 · Cited by 40 · see citing works

B-Myb Mediates Proliferation and Migration of Non-Small-Cell Lung Cancer via Suppressing IGFBP3

Fan, X., Wang, Y., Jiang, T., Cai, W. L., Jin, Y., Niu, Y., Zhu, H., & Bu, Y. (2018) · International Journal of Molecular Sciences · doi:10.3390/ijms19051479 · Cited by 39 · see citing works

Preferential Autoimmune Response in Prostate Cancer to Cyclin B1 in a Panel of Tumor-Associated Antigens

Dai, L., Li, J., Ortega, R., Qian, W., Casiano, C. A., & Zhang, J.-Y. (2014) · Journal of Immunology Research · doi:10.1155/2014/827827 · Cited by 36 · see citing works

MuvB: A Key to Cell Cycle Control in Ovarian Cancer

Iness, A. N., & Litovchick, L. (2018) · Frontiers in Oncology · doi:10.3389/fonc.2018.00223 · Cited by 34 · see citing works

B-Myb accelerates colorectal cancer progression through reciprocal feed-forward transactivation of E2F2

Fan, X., Wang, Y., Jiang, T., Liu, T., Jin, Y., Du, K., Niu, Y., Zhang, C., Liu, Z., Lei, Y., et al. (2021) · Oncogene · doi:10.1038/s41388-021-01961-9 · Cited by 34 · see citing works

A functional variant at the miRNA binding site in HMGB1 gene is associated with risk of oral squamous cell carcinoma

Lin, C., Chou, Y., Yeh, C., Yang, S., Chuang, C., & Liu, Y. (2017) · Oncotarget · doi:10.18632/oncotarget.16120 · Cited by 31 · see citing works

CENPA is one of the potential key genes associated with the proliferation and prognosis of ovarian cancer based on integrated bioinformatics analysis and regulated by MYBL2

Han, J., Xie, R., Yang, Y., Chen, D., Liu, L., Wu, J., & Li, S. (2021) · Translational Cancer Research · doi:10.21037/tcr-21-175 · Cited by 31 · see citing works

Regulation of carboxylesterase‐2 expression by p53 family proteins and enhanced anti‐cancer activities among 5‐fluorouracil, irinotecan and doxazolidine prodrug

Xiao, D. W., Yang, D., Guo, L., Lü, W., Charpentier, M. M., & Yan, B. (2013) · British Journal of Pharmacology · doi:10.1111/bph.12125 · Cited by 29 · see citing works

MYBL2 is a Potential Prognostic Marker that Promotes Cell Proliferation in Gallbladder Cancer

Liang, H., Cao, Y., Ma, Q., Shu, Y.-J., Wang, Z., Zhang, F., Ye, Y.-Y., Li, H.-F., Xiang, S.-S., Song, X.-L., et al. (2017) · Cellular Physiology and Biochemistry · doi:10.1159/000475454 · Cited by 28 · see citing works

Transcriptional regulators in hepatocarcinogenesis – Key integrators of malignant transformation

Malz, M., Pinna, F., Schirmacher, P., & Breuhahn, K. (2012) · Journal of Hepatology · doi:10.1016/j.jhep.2011.11.029 · Cited by 25 · see citing works

Molecular Insights on Post-chemotherapy Retinoblastoma by Microarray Gene Expression Analysis

Venkatesan, N., Segu, R., Deepa, P. R., Khetan, V., Vasudevan, M., & Krishnakumar, S. (2013) · Bioinformatics and Biology Insights · doi:10.4137/bbi.s12494 · Cited by 24 · see citing works

LIN9 confers paclitaxel resistance in triple negative breast cancer cells by upregulating CCSAP

Lai, H., Wang, R., Li, S., Shi, Q., Cai, Z., Li, Y., & Liu, Y. (2019) · Science China Life Sciences · doi:10.1007/s11427-019-9581-8 · Cited by 20 · see citing works

Increased MYBL2 expression in aggressive hormone‐sensitive prostate cancer

Yoshikawa, Y., Stopsack, K. H., Wang, V., Chen, Y., Mazzu, Y. Z., Burton, F., Chakraborty, G., Rajanala, S. H., Hirani, R., Nandakumar, S., et al. (2022) · Molecular Oncology · doi:10.1002/1878-0261.13314 · Cited by 18 · see citing works

Experimental Models to Define the Genetic Predisposition to Liver Cancer

Pascale, R. M., Simile, M. M., Peitta, G., Seddaiu, M. A., Feo, F., & Calvisi, D. F. (2019) · Cancers · doi:10.3390/cancers11101450 · Cited by 18 · see citing works

Association between B‑Myb proto‑oncogene and the development of malignant tumors (Review)

Jin, Y., Qi, G., Chen, G., Wang, C., & Fan, X. (2021) · Oncology Letters · doi:10.3892/ol.2021.12427 · Cited by 17 · see citing works

Testing an Aflatoxin B1 Gene Signature in Rat Archival Tissues

Merrick, B. A., Auerbach, S. S., Stockton, P. S., Foley, J. F., Malarkey, D. E., Sills, R. C., Irwin, R. D., & Tice, R. R. (2012) · Chemical Research in Toxicology · doi:10.1021/tx3000945 · Cited by 17 · see citing works

Structure and function of MuvB complexes

Müller, G. A., Asthana, A., & Rubin, S. M. (2022) · Oncogene · doi:10.1038/s41388-022-02321-x · Cited by 17 · see citing works

Essential meiotic structure-specific endonuclease1 ( EME1 ) promotes malignant features in gastric cancer cells via the Akt/GSK3B/CCND1 pathway

Guo, Z., Liang, E., Li, W., Jiang, L., & Zhi, F. (2021) · Bioengineered · doi:10.1080/21655979.2021.1999371 · Cited by 15 · see citing works

DREAM a little dREAM of DRM: Model organisms and conservation of DREAM‐like complexes

Hoareau, M., Rincheval‐Arnold, A., Gaumer, S., & Guénal, I. (2023) · BioEssays · doi:10.1002/bies.202300125 · Cited by 14 · see citing works

B-MYB—p53-related relevant regulator for the progression of clear cell renal cell carcinoma

Nientiedt, M., Müller, K., Nitschke, K., Erben, P., Steidler, A., Porubský, Š., Popović, Z. V., Waldbillig, F., Mühlbauer, J., & KRIEGMAIR, M. C. (2020) · Journal of Cancer Research and Clinical Oncology · doi:10.1007/s00432-020-03392-7 · Cited by 14 · see citing works

High expression of FOXM1 critical for sustaining cell proliferation in mitochondrial DNA-less liver cancer cells

Higurashi, M., Maruyama, T., Nogami, Y., Ishikawa, F., Yoshida, Y., Mori, K., Fujita, K., & Shibanuma, M. (2020) · Experimental Cell Research · doi:10.1016/j.yexcr.2020.111889 · Cited by 14 · see citing works

Sofosbuvir Activates EGFR-Dependent Pathways in Hepatoma Cells with Implications for Liver-Related Pathological Processes

Bojková, D., Westhaus, S., Costa, R., Timmer, L., Funkenberg, N., Korencak, M., Streeck, H., Vondran, F. W. R., Broering, R., Heinrichs, S., et al. (2020) · Cells · doi:10.3390/cells9041003 · Cited by 14 · see citing works

MYBL2 regulates de novo purine synthesis by transcriptionally activating IMPDH1 in hepatocellular carcinoma cells

Zhao, J., Wang, W., Liu, T., Zhang, L., Lin, D., Yao, J., Peng, X., Jin, G., Ma, T.-T., Gao, J., et al. (2022) · BMC Cancer · doi:10.1186/s12885-022-10354-4 · Cited by 12 · see citing works

Differential Network Analysis Applied to Preoperative Breast Cancer Chemotherapy Response

Warsow, G., Struckmann, S., Kerkhoff, C., Reimer, T., Engel, N., & Fuellen, G. (2013) · PLoS ONE · doi:10.1371/journal.pone.0081784 · Cited by 12 · see citing works

Cutaneous cylindroma: it's all about MYB

Corda, G., & Sala, A. (2016) · The Journal of Pathology · doi:10.1002/path.4746 · Cited by 12 · see citing works

PEX5 deficiency enhances radiosensitivity via MGST1-GSH detoxifying function and promotes ferroptosis in liver cancer

Yuan, Z., Liu, T., Jiang, P. X., Zhao, Y., Guo, R., Ye, X., He, Q., Wang, H., Xue, L., & Wang, J. (2025) · Science China Life Sciences · doi:10.1007/s11427-024-2938-3 · Cited by 11 · see citing works

Characteristic genomics of peripheral blood mononuclear cells of hepatocellular carcinoma patients with liver-kidney yin deficiency syndrome

Weng, L. (2012) · Journal of Chinese Integrative Medicine · doi:10.3736/jcim20120409 · Cited by 9 · see citing works

Identification of potential therapeutic targets in hepatocellular carcinoma using an integrated bioinformatics approach

Huang, Q., Li, J., & Wei, A. (2018) · Translational Cancer Research · doi:10.21037/tcr.2018.06.04 · Cited by 9 · see citing works

MYBL2 protects against H9c2 injury induced by hypoxia via AKT and NF‑κB pathways

Shao, M., Ren, Z., & Zhang, R. (2018) · Molecular Medicine Reports · doi:10.3892/mmr.2018.8387 · Cited by 8 · see citing works

Identifying Prognostic Significance of RCL1 and Four-Gene Signature as Novel Potential Biomarkers in HCC Patients

Liu, J., Zhang, S., Chen, J., Li, Z., Chen, J., Lu, Q., Han, Y., Dai, W., Xie, C., & Li, J. (2021) · Journal of Oncology · doi:10.1155/2021/5574150 · Cited by 8 · see citing works

Clinical evidence for a role of E2F1-induced replication stress in modulating tumor mutational burden and immune microenvironment

Tan, K., Song, Y., Xu, M., & You, Z. (2023) · DNA repair · doi:10.1016/j.dnarep.2023.103531 · Cited by 4 · see citing works

Experimental Models to Define the Genetic Predisposition to Liver Cancer

Pascale, R. M., Simile, M. M., Peitta, G., Feo, F., & Calvisi, D. F. (2020) · Vide Leaf, Hyderabad eBooks · doi:10.37247/pacr.1.2020.6 · Cited by 3 · see citing works

Combinatorial transcriptional regulation of HEB/ZEB1/ASCL1 and MYBL2 on Ras/ErbB signaling

Zhong, F., Chen, T., & Li, B. (2022) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2022.07.046 · Cited by 2 · see citing works

Dissecting novel mechanisms of hepatitis B virus related hepatocellular carcinoma using meta-analysis of public data

Aljabban, J., Rohr, M., Syed, S. A., Cohen, E., Hashi, N. J., Syed, S., Khorfan, K., Aljabban, H., Borkowski, V. J., Segal, M., et al. (2022) · World Journal of Gastrointestinal Oncology · doi:10.4251/wjgo.v14.i9.1856 · Cited by 1 · see citing works

Prognostic value of MYBL2 and its potential implications for immunotherapy: a study of bioinformatics and experimental validation

Pei, J., Fan, J., Liao, Y., Li, M., Bai, X., Wang, Y., Zhang, H., Kong, Y., & wang, G. (2025) · British Journal of Cancer · doi:10.1038/s41416-025-03253-5 · Cited by 1 · see citing works

Role of transcription factors in hepatocellular carcinoma

Shinde, S. D., Kulkarni, N., Sahu, B., Kalia, K., & Behera, S. K. (2022) · Elsevier eBooks · doi:10.1016/b978-0-323-98807-0.00007-7 · Cited by 1 · see citing works

Identification of nine key genes by Bioinformatics Analysis for Predicting poor Prognosis In Smoking-Induced Lung Adenocarcinoma

Ren, C., Sun, W., Xu, L., & Han, C. (2020) · Lung Cancer Management · doi:10.2217/lmt-2020-0009 · Cited by 1 · see citing works

A Graph-Theoretic Approach to Model Genomic Data and Identify Biological Modules Asscociated with Cancer Outcomes

Petrochilos, D. (2013) · ResearchWorks at the University of Washington (University of Washington)

MYBL2 regulates de novo purine synthesis by transcriptionally activating IMPDH1 in hepatocellular carcinoma cellsPreprint

Zhao, J., Wang, W., Liu, T., Zhang, L., Lin, D., Yao, J., Peng, X., Jin, G., Ma, T.-T., Gao, J., et al. (2022) · Research Square · doi:10.21203/rs.3.rs-1597599/v1

Computational and statistical analyses of omics data to advance understanding of hormone-dependent cancers

Jayarathna, D. K. (2023) · Queensland University of Technology · doi:10.5204/thesis.eprints.237470

Additional file 3 of MYBL2 regulates de novo purine synthesis by transcriptionally activating IMPDH1 in hepatocellular carcinoma cells

Zhao, J.-Z., Wang, W., Liu, T., Zhang, L., lin, D., Yao, J.-Y., Peng, X., Jin, G., Ma, T.-T., Gao, J.-B., et al. (2023) · Figshare · doi:10.6084/m9.figshare.22604797

Additional file 5 of MYBL2 regulates de novo purine synthesis by transcriptionally activating IMPDH1 in hepatocellular carcinoma cells

Zhao, J.-Z., Wang, W., Liu, T., Zhang, L., lin, D., Yao, J.-Y., Peng, X., Jin, G., Ma, T.-T., Gao, J.-B., et al. (2023) · Figshare · doi:10.6084/m9.figshare.22604806

Additional file 2 of MYBL2 regulates de novo purine synthesis by transcriptionally activating IMPDH1 in hepatocellular carcinoma cells

Zhao, J.-Z., Wang, W., Liu, T., Zhang, L., lin, D., Yao, J.-Y., Peng, X., Jin, G., Ma, T.-T., Gao, J.-B., et al. (2023) · Figshare · doi:10.6084/m9.figshare.22604794

Additional file 4 of MYBL2 regulates de novo purine synthesis by transcriptionally activating IMPDH1 in hepatocellular carcinoma cells

Zhao, J.-Z., Wang, W., Liu, T., Zhang, L., lin, D., Yao, J.-Y., Peng, X., Jin, G., Ma, T.-T., Gao, J.-B., et al. (2023) · Figshare · doi:10.6084/m9.figshare.22604803

Additional file 1 of MYBL2 regulates de novo purine synthesis by transcriptionally activating IMPDH1 in hepatocellular carcinoma cells

Zhao, J.-Z., Wang, W., Liu, T., Zhang, L., lin, D., Yao, J.-Y., Peng, X., Jin, G., Ma, T.-T., Gao, J.-B., et al. (2023) · Figshare · doi:10.6084/m9.figshare.22604791

L'Attivazione del complesso MYBL2-LIN9 contribuisce all'epatocancerogenesi umana ed identifica un sottogruppo di epatocarcinomi con p53 mutato

Balzani, S. (2012) · UnissResearch (Università degli Studi di Sassari)

Mybl2 expression is under genetic control and contributes to determine a hepatocellular carcinoma susceptible phenotype

Frau, M., Ladu, S., Calvisi, D. F., Simile, M. M., Bonelli, P., Daino, L., Tomasi, M. L., Seddaiu, M. A., Feo, F., & Pascale, R. M. (2011) · Journal of Hepatology · doi:10.1016/j.jhep.2010.10.031 · Cited by 60 · see citing works

High MYBL2 expression and transcription regulatory activity is associated with poor overall survival in patients with hepatocellular carcinoma

Guan, Z., Cheng, W., Huang, D., & Wei, A. (2017) · Current Research in Translational Medicine · doi:10.1016/j.retram.2017.11.002 · Cited by 43 · see citing works

LINC 01287 regulates tumorigenesis and invasion via miR‐298/ MYB in hepatocellular carcinoma

Mo, Y., He, L., Lai, Z., Wan, Z., Chen, Q., Pan, S., Li, L., Li, D., Huang, J., Xue, F., et al. (2018) · Journal of Cellular and Molecular Medicine · doi:10.1111/jcmm.13818 · Cited by 18 · see citing works

Integrative Machine Learning and Experimental Validation Identify MYBL2 as a Prognostic Biomarker and Therapeutic Target in Hepatocellular Carcinoma

Yang, Y.-L., Huang, Y.-H., & Lin, H.-Y. (2026) · Oncology Research · doi:10.32604/or.2026.075284