The DOI matches its Crossref record; 11 of the 11 references it cites were found in a registry or an index.
Caffeine and stress alter salivary α‐amylase activity in young men
Abstract
Objective: We examined the effects of caffeine and a psychological stressor on salivary α‐amylase (sAA) in healthy young males (age 18–30 years) who consumed caffeine on a daily basis. Methods: Using a between‐subjects, double‐blind, placebo‐controlled design, 45 participants received either 200 or 400 mg of caffeine (Vivarin®) or placebo, rested for 20 min, and then performed 20 min of mental arithmetic. Saliva samples (assayed for sAA and caffeine), blood pressure, and heart rate were taken before (baseline) and 15 min after the math stressor (stress). Results: Baseline sAA activity did not differ among the treatment groups; however, there was a statistically significant time by caffeine group interaction. Changes in sAA activity across the session were dependent on the amount of caffeine consumed. Following the challenge period, sAA activity among the placebo group was the lowest and sAA activity among the 400 mg treatment group was the highest. Separate repeated‐measures ANOVAs conducted for each drug treatment group revealed that sAA activity increased in response to stress and caffeine (i.e., 200 and 400 mg groups) but not to stress alone (i.e., placebo group). Conclusions: Findings provide evidence for acute sAA changes in response to caffeine and stress in habitual caffeine users. Copyright © 2010 John Wiley & Sons, Ltd.
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“In healthy young individuals, the administration of caffeine was reported to either activate [5] or not influence [6] the secretion of sAA.”
From Effects of Coffee on the Gastro-Intestinal Tract: A Narrative Review and Literature Update (2022) · cites this paper as [5]
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Nater, U. M., & Rohleder, N. (2009) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2009.01.014 · Cited by 1,370
Determinants of the diurnal course of salivary alpha-amylase
Nater, U. M., Rohleder, N., Schlotz, W., Ehlert, U., & Kirschbaum, C. (2007) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2007.02.007 · Cited by 631 · cited 7×
“In contrast, Nater et al. (2007) obtained sAA levels and self-reported caffeine intake amounts across the day, which could not account for individual differences in the duration of caffeinated beverage consumption in connection with each sAA assessment or the concurrent experience of stress during…”
BackgroundResultInfluentialStress response and the adolescent transition: performance versus peer rejection stressors
Stroud, L. R., Foster, E., Papandonatos, G. D., Handwerger, K., Granger, D. A., Kivlighan, K. T., & Niaura, R. (2009) · Development and Psychopathology · doi:10.1017/s0954579409000042 · Cited by 610
Self-citationSalivary α‐Amylase in Biobehavioral Research: Recent Developments and Applications
GRANGER, D. A., KIVLIGHAN, K. T., El‐SHEIKH, M., GORDIS, E. B., & STROUD, L. R. (2007) · Annals of the New York Academy of Sciences · doi:10.1196/annals.1384.008 · Cited by 572
Self-citationROHLEDER, N., NATER, U. M., WOLF, J. M., EHLERT, U., & KIRSCHBAUM, C. (2004) · Annals of the New York Academy of Sciences · doi:10.1196/annals.1314.033 · Cited by 520
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“After capsule administration, participants were asked to rest for 20 min to allow for adequate caffeine absorption and to ensure that participants were completing the mental arithmetic task when plasma caffeine levels were on the ascending limb of the absorption curve (Bonati et al., 1982; Liguori et al., 1997); blood…”
BackgroundMethod(2006) · Pharmacology Biochemistry and Behavior · doi:10.1016/j.pbb.2006.03.005 · Cited by 213 · cited 2×
“…to stress and caffeine, a finding consistent with published data (al’Absi et al., 1997; al’Absi et al., 1998; al’Absi et al., 2003; Hartley et al., 2004; Lovallo et al., 2006), and that these elevations would be positively associated with elevated salivary caffeine levels (Laurent et al., 2000).”
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Liguori, A. (1997) · Pharmacology Biochemistry and Behavior · doi:10.1016/s0091-3057(97)00003-8 · Cited by 168
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Cited by
Effects of Coffee on the Gastro-Intestinal Tract: A Narrative Review and Literature Update
Nehlig, A. (2022) · Nutrients · doi:10.3390/nu14020399 · Cited by 158
Unno, K., Noda, S., Kawasaki, Y., Yamada, H., Morita, A., Iguchi, K., & Nakamura, Y. (2017) · Nutrients · doi:10.3390/nu9070777 · Cited by 65
Papakonstantinou, E., Kechribari, I., Sotirakoglou, Κ., Tarantilis, P., Gourdomichali, T., Michas, G., Kravvariti, V., Voumvourakis, K., & Zampelas, A. (2015) · Nutrition Journal · doi:10.1186/s12937-016-0146-0 · Cited by 59
“Moreover, a few studies [34], but not all [35], have suggested that caffeinated coffee may activate the sympathetic nervous system (SNS), via secretion of salivary alpha-amylase (sAA) [36–40], an enzyme involved in polysaccharide digestion [41].”
BackgroundResultUnno, K., Noda, S., Kawasaki, Y., Yamada, H., Morita, A., Iguchi, K., & Nakamura, Y. (2017) · Journal of Clinical Biochemistry and Nutrition · doi:10.3164/jcbn.17-6 · Cited by 39
Anti-stress effect of green tea with lowered caffeine on humans: a pilot study
Unno, K., Yamada, H., Iguchi, K., Ishida, H., Iwao, Y., Morita, A., & Nakamura, Y. (2017) · Biological & Pharmaceutical Bulletin · doi:10.1248/bpb.b17-00141 · Cited by 29
Stress response to virtual reality based active shooter training: Impact of caffeine consumption
McAllister, M. J., Martaindale, M. H., Dillard, C. C., & Gonzalez, D. E. (2024) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2023.106923 · Cited by 8
Metadata
- Authors
- Klein, L. C., Bennett, J. M., Whetzel, C. A., Granger, D. A., & Ritter, F. E.
- Venue
- Human Psychopharmacology: Clinical and Experimental
- Publisher
- Wiley
- Published
- 2010-06-29
- Volume
- 25
- Issue
- 5
- Pages
- 359-367
- ISSN
- 0885-6222
- 1099-1077
- Cited by
- 46
- References
- 11
- Language
- en
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