Urolithin B, a Newly Identified Regulator of Skeletal Muscle Mass

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Apigenin inhibits sciatic nerve denervation–induced muscle atrophy

Choi, W. H., Jang, Y. J., Son, H. J., Ahn, J., Jung, C. H., & Ha, T. Y. (2018) · Muscle & Nerve · doi:10.1002/mus.26133 · Cited by 29 · see citing works

Urolithins: A Prospective Alternative against Brain Aging

An, L., Lu, Q., Wang, K., & Wang, Y. (2023) · Nutrients · doi:10.3390/nu15183884 · Cited by 27 · see citing works

Using polyphenol derivatives to prevent muscle wasting

Francaux, M., & Deldicque, L. (2018) · Current Opinion in Clinical Nutrition & Metabolic Care · doi:10.1097/mco.0000000000000455 · Cited by 21 · see citing works

Muscle Disuse Atrophy Caused by Discord of Intracellular Signaling

Ji, L. L., Yeo, D., & Kang, C. (2020) · Antioxidants and Redox Signaling · doi:10.1089/ars.2020.8072 · Cited by 21 · see citing works

Implication of the Gut Microbiota in Metabolic Inflammation Associated with Nutritional Disorders and Obesity

Rodriguez, J., Olivares, M., & Delzenne, N. M. (2020) · Molecular Nutrition & Food Research · doi:10.1002/mnfr.201900481 · Cited by 20 · see citing works

Comparative Analysis of the Impact of Urolithins on the Composition of the Gut Microbiota in Normal-Diet Fed Rats

Khalaf, A. K. A., Abdulrahman, A. O., Kaleem, M., Nur, S. M., Asseri, A. H., Choudhry, H., & Khan, M. I. (2021) · Nutrients · doi:10.3390/nu13113885 · Cited by 19 · see citing works

Urolithins: The Colon Microbiota Metabolites as Endocrine Modulators: Prospects and Perspectives

Vini, R., Azeez, J. M., Remadevi, V., Susmi, T. R., Ayswarya, R. S., Sujatha, A. S., Parvathy, M., Lathika, L. M., & Sreeja, S. (2022) · Frontiers in Nutrition · doi:10.3389/fnut.2021.800990 · Cited by 23 · see citing works

Role for Plant-Derived Antioxidants in Attenuating Cancer Cachexia

Li, W., Swiderski, K., Murphy, K. T., & Lynch, G. S. (2022) · Antioxidants · doi:10.3390/antiox11020183 · Cited by 16 · see citing works

Review of Clinical Effects and Presumed Mechanism of Action of the French Oak Wood Extract Robuvit

Weichmann, F., Avaltroni, F., & Bürki, C. (2021) · Journal of Medicinal Food · doi:10.1089/jmf.2020.0165 · Cited by 14 · see citing works

Urolithin B inhibits proliferation and migration and promotes apoptosis and necrosis by inducing G2/M arrest and targeting MMP‐2/‐9 expression in osteosarcoma cells

Nasab, N. T., Jalili‐Nik, M., Afshari, A. R., Farimani, A. R., & Soukhtanloo, M. (2023) · Journal of Biochemical and Molecular Toxicology · doi:10.1002/jbt.23486 · Cited by 13 · see citing works

Constituents and Metabolites of a French Oak Wood Extract (Robuvit®) in Serum and Blood Cell Samples of Women Undergoing Hysterectomy

Volpp, L., Ferianec, V., Ježovičová, M., Ďuračková, Z., Scherf‐Clavel, O., & Högger, P. (2020) · Frontiers in Pharmacology · doi:10.3389/fphar.2020.00074 · Cited by 12 · see citing works

A Bioassay-Guided Fractionation of Rosemary Leaf Extract Identifies Carnosol as a Major Hypertrophy Inducer in Human Skeletal Muscle Cells

Morel, S., Hugon, G., Vitou, M., Védère, M., Fons, F., Rapior, S., Saint, N., & Carnac, G. (2021) · Nutrients · doi:10.3390/nu13124190 · Cited by 11 · see citing works

Polyphenol blend enhances zootechnical performance, improves meat quality, and reduces the severity of wooden breast in broiler chickens

de Castilho, V. A. R., Burbarelli, M. F. D. C., Przybulinski, B. B., Garcia, L. C., Vieira, J. R. R. F., Garcia, R. G., Caldara, F. R., Santín, E., Cardoso, C. A. L., & Komiyama, C. M. (2025) · Frontiers in Veterinary Science · doi:10.3389/fvets.2025.1584897 · Cited by 12 · see citing works

Hesperetin but not ellagic acid increases myosin heavy chain expression and cell fusion in C2C12 myoblasts in the presence of oxidative stress

Cuijpers, I., Dohmen, C. G. M., Bouwman, F. G., Troost, F. J., & Sthijns, M. M. J. P. E. (2024) · Frontiers in Nutrition · doi:10.3389/fnut.2024.1377071 · Cited by 9 · see citing works

Fatigue due to mild heart failure: effects of Robuvit® in a concept, pilot registry study

Belcaro, G., Cesarone, M. R., SCIPIONE, V., SCIPIONE, C., Dugall, M., Hu, S., Hosoi, M., Cotellese, R., Olivieri, N., Feragalli, B., et al. (2020) · Minerva Cardioangiologica · doi:10.23736/s0026-4725.19.05029-1 · Cited by 8 · see citing works

Nutritional strategies targeting age-related skeletal muscle fibrosis: underlying mechanisms

Cuijpers, I., Katsburg, J., van Loon, L. J. C., Troost, F. J., & Sthijns, M. M. J. P. E. (2025) · Critical Reviews in Food Science and Nutrition · doi:10.1080/10408398.2025.2498676 · Cited by 7 · see citing works

Polyunsaturated fatty acids, polyphenols, amino acids, prebiotics

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The polyphenol metabolite urolithin A suppresses myostatin expression and augments glucose uptake in human skeletal muscle cells

Wilhelmsen, A., Karagounis, L. G., Bennett, A. J., D'Amico, D. F., Fouassier, A. M., Jones, S. W., & Tsintzas, K. (2025) · Nutrition & Metabolism · doi:10.1186/s12986-025-00909-0 · Cited by 6 · see citing works

Urolithin A Exhibits Antidepressant-like Effects by Modulating the AMPK/CREB/BDNF Pathway

Di, Y., Xue, R., Li, X., Jin, Z., Li, H., Wu, L., Zhang, Y., & An, L. (2025) · Nutrients · doi:10.3390/nu17142294 · Cited by 6 · see citing works

Hangover and fatigue: effects of Robuvit® supplementation. A pilot registry study

Hu, S., Belcaro, G. V., Cesarone, M. R., SCIPIONE, C., SCIPIONE, V., Hosoi, M., Cornelli, U., PELLEGRINI, L., Dugall, M., Feragalli, B., et al. (2020) · Minerva Cardioangiologica · doi:10.23736/s0026-4725.19.05028-x · Cited by 6 · see citing works

Advances in identifying functional groups in carnosol analogues to address their efficacy in skeletal muscle function

Berger, A., Sarniguet, J., Hugon, G., Cubedo, N., Morel, S., Chabi, B., Vernus, B., Bonnieu, A., Brun, A., Matecki, S., et al. (2025) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2025.118397 · Cited by 4 · see citing works

Prevention of work-related stress, fatigue, loss of cognitive function, improved attention and recovery of stamina with Robuvit® in professionals with increased oxidative stress

Belcaro, G. V., Cesarone, M. R., Saggino, A., Dugall, M., Hu, S., SCIPIONE, C., SCIPIONE, V., Cornelli, U., Hosoi, M., Cotellese, R., et al. (2021) · Minerva Medica · doi:10.23736/s0026-4806.21.07776-4 · Cited by 4 · see citing works

Sopherone A and B: Two new biologically relevant dibenzo-α-pyrones from Cassia sophera

Brahmachari, G., Mandal, B., Mandal, M., & Mondal, A. (2019) · Fitoterapia · doi:10.1016/j.fitote.2019.05.008 · Cited by 4 · see citing works

Postoperative Stress, Metabolism, and Catabolism

Calvani, R., Picca, A., Coelho‐Júnior, H. J., Tosato, M., & Marzetti, E. (2024) · Practical issues in geriatrics · doi:10.1007/978-3-031-77707-3_21 · Cited by 3 · see citing works

Protective effect of Luffa cylindrica Roemer against dexamethasone-induced muscle atrophy in primary rat skeletal muscle cells

Yeo, C., Kim, H., Jeon, W., Lee, J., Hong, J. Y., Kim, H., Lee, Y. J., Baek, S. H., & Ha, I. (2023) · Journal of Muscle Research and Cell Motility · doi:10.1007/s10974-023-09661-5 · Cited by 3 · see citing works

Urolithins in clinical translation: from gut microbial metabolites to precision interventions

Hu, L., Ling, Y., & Jin, W. (2026) · Frontiers in Nutrition · doi:10.3389/fnut.2026.1854240 · Cited by 2 · see citing works

Cachexia and phytonutrients

Fakhri, S., Piri, S., & Khan, H. Z. (2022) · Elsevier eBooks · doi:10.1016/b978-0-12-824356-5.00007-2 · Cited by 2 · see citing works

Robuvit® reduces fatigue after chemotherapy for colon cancer. A pilot registry study

Belcaro, G. V., David, C. O. X., Cesarone, M. R., SCIPIONE, C., SCIPIONE, V., Dugall, M., Hu, S., Corsi, M., Cornelli, U., Feragalli, B., et al. (2023) · Minerva Surgery · doi:10.23736/s2724-5691.23.09885-4 · Cited by 2 · see citing works

Changes in the biochemical composition of broiler body tissues when feeding with Bacillus cereus probiotic and coumarin

Duskaev, G. K., Nurzhanov, B. S., & Rakhmatullin, S. G. (2022) · BIO Web of Conferences · doi:10.1051/bioconf/20225101004 · Cited by 1 · see citing works

Effect of iodixanol and propylene glycol as clearing agents in extensor digitorum longus and soleus muscles: mechanical and morphological characterization using the optical coherence tomography technique

Huertas, J. F. E., Vaca‐González, J. J., Garzón–Alvarado, D. A., & Trabelsi, O. (2024) · Biomaterials Science · doi:10.1039/d4bm00207e · Cited by 1 · see citing works

Skeletal Muscle Disorders: Navigating Management and Natural Products

El‐Sayed, H. M., Hussien, K. H., Ghaiad, H. R., Abd‐Elmawla, M. A., Abdelmaksoud, N. M., Ramadan, A., El‐Shiekh, R. A., & Zaki, M. B. (2026) · Chemistry & Biodiversity · doi:10.1002/cbdv.202501803 · Cited by 1 · see citing works

Urolithins: microbial biosynthesis, metabolic pathways and health benefits for functional food and cosmeceutical applications

Srinivasan, J., Vinchurkar, R. V., Sangam, S., Fadare, O. S., Vishweswaraiah, R. H., & Pradhan, D. (2026) · Food Science and Biotechnology · doi:10.1007/s10068-026-02136-6 · Cited by 1 · see citing works

Turning off inflammation naturally via dual antioxidant and anti-inflammatory actions of chestnut wood extract through PPARγ and NF-κB pathways

Lambert, D., Buisine, M., Billamboz, M., & Jawhara, S. (2026) · PLoS ONE · doi:10.1371/journal.pone.0347987 · Cited by 1 · see citing works

Urolithin A enhances mitochondrial biogenesis-related markers and maximal respiratory capacity during C2C12 differentiation

Vargas-Foitzick, R., Irribarra-Tapia, D., Valero‐Breton, M., & Balboa, E. (2026) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2026.1854844 · Cited by 1 · see citing works

Diet and Muscle Metabolism

Azzolino, D., Gianturco, V., & Calvani, R. (2025) · Nutrients · doi:10.3390/nu17101727 · Cited by 1 · see citing works

Suppléments oraux d’acides amines essentiels (AAE) et d’éllagitannins chez le patient hémodialysé

Treille, S., Dewez, F., Asta, S., Benahmed, A., Legrand, A., & Guillaume, B. (2019) · Nutrition Clinique et Métabolisme · doi:10.1016/j.nupar.2019.01.355

Patent Highlights August–September 2022

Mucke, H. A. (2023) · Pharmaceutical Patent Analyst · doi:10.4155/ppa-2022-0049

Sarcopenia: effects of Robuvit® supplementation on loss of muscular mass and strength

Belcaro, G., Cesarone, M. R., Dugall, M., Bavera, P. M., Ledda, A. G., SCIPIONE, C., SCIPIONE, V., Corsi, M., David, C. O. X., Hosoi, M., et al. (2026) · Minerva Medica · doi:10.23736/s0026-4806.25.09735-6

The Importance of the Gut–Muscle Axis: From Mechanistic Insights in Cell Culture and Rodent Models to Descriptive and Associative Evidence in Livestock

Ringseis, R., Eder, K., & Geßner, D. K. (2026) · Animals · doi:10.3390/ani16162594

Exploring the Impact of Urolithins A and B on Muscle Health: A Transcriptomic Analysis in Human Myotubes

Henrotin, Y., Florin, A., Sanchez, C., Centonze, P., Coelho, T. P., Bekisz, S., Dubuc, J., Galand, O., & Lambert, C. (2026) · Journal of Cachexia Sarcopenia and Muscle · doi:10.1002/jcsm.70385

Targeting ubiquitin-dependent mitochondrial autophagy and apoptosis in sarcopenia: the therapeutic potential of phytochemicals

Zeng, Y., & Wang, P. (2026) · Discover Nano · doi:10.1186/s11671-026-05041-3

Identification de l’urolithine B comme un nouveau régulateur de la masse musculaire

Rodriguez, J., Pierre, N., Naslain, D., Bontemps, F., Ferreira, D., Priem, F., Deldicque, L., & Francaux, M. (2016) · Nutrition Clinique et Métabolisme · doi:10.1016/j.nupar.2016.09.068

Pharmacological Effects of Urolithin A and Its Role in Muscle Health and Performance: Current Knowledge and Prospects

Zhao, H., Song, G., Zhu, H., Qian, H., Pan, X., Song, X., Xie, Y., & Liu, C. (2023) · Nutrients · doi:10.3390/nu15204441 · Cited by 64 · see citing works

AB1395 UROLITHIN A AND B ACCELERATE MYOCYTE FUSION INTO MYOTUBES

Henrotin, Y. E., Lambert, C., Florin, A., Zappia, J., Centonze, P., & Sanchez, C. (2023) · Annals of the Rheumatic Diseases · doi:10.1136/annrheumdis-2023-eular.3536

Molecular mechanisms modulating muscle mass

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mRNA Expression Signatures of Human Skeletal Muscle Atrophy Identify a Natural Compound that Increases Muscle Mass

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