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Cited by 985

The DOI matches its Crossref record; 27 of the 27 references it cites were found in a registry or an index.

Continuous flow‐driven inversion for arterial spin labeling using pulsed radio frequency and gradient fields

Open access
Dai, Weiying, Garcia, Dairon, de Bazelaire, Cedric, Alsop, David C.·2008·Magnetic Resonance in Medicine
DOI 10.1002/mrm.21790
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Abstract

Continuous labeling by flow‐driven adiabatic inversion is advantageous for arterial spin labeling (ASL) perfusion studies, but details of the implementation, including inefficiency, magnetization transfer, and limited support for continuous‐mode operation on clinical scanners, have restricted the benefits of this approach. Here a new approach to continuous labeling that employs rapidly repeated gradient and radio frequency (RF) pulses to achieve continuous labeling with high efficiency is characterized. The theoretical underpinnings, numerical simulations, and in vivo implementation of this pulsed continuous ASL (PCASL) method are described. In vivo PCASL labeling efficiency of 96% relative to continuous labeling with comparable labeling parameters far exceeded the 33% duty cycle of the PCASL RF pulses. Imaging at 3T with body coil transmission was readily achieved. This technique should help to realize the benefits of continuous labeling in clinical imagers. Magn Reson Med 60:1488–1497, 2008. © 2008 Wiley‐Liss, Inc.

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Metadata

Authors
Dai, W., Garcia, D., de Bazelaire, C., & Alsop, D. C.
Venue
Magnetic Resonance in Medicine
Publisher
Wiley
Published
2008-11-24
Volume
60
Issue
6
Pages
1488-1497
ISSN
  • 0740-3194 (ISSN-L)
  • 1522-2594
DOI
10.1002/mrm.21790
OpenAlex
W2077466520
Cited by
985
References
27
FWCI
25.09
Type
journal article
Language
en
Open access
bronze

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