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Cited by 322

The DOI matches its Crossref record; 21 of the 21 references it cites were found in a registry or an index.

Optimized 3D ultrashort echo time pulmonary MRI

Open access
Johnson, Kevin M., Fain, Sean B., Schiebler, Mark L., Nagle, Scott·2013·Magnetic Resonance in Medicine

Abstract

Purpose: To optimize 3D radial ultrashort echo time MRI for high resolution whole‐lung imaging. Methods: 3D radial ultrashort echo time was implemented on a 3T scanner to investigate the effects of: (1) limited field‐of‐view excitation, (2) variable density readouts, and (3) radial oversampling. Improvements in noise performance and spatial resolution were assessed through simulation and phantom studies. Their effects on lung and airway visualization in five healthy male human subjects (mean age 32 years) were compared qualitatively through blinded ordinal scoring by two cardiothoracic radiologists using a nonparametric Friedman test (P < 0.05). Relative signal difference between endobronchial air and adjacent lung tissue, normalized to nearby vessel, was used as a surrogate for lung tissue signal. Quantitative measures were compared using the paired Student's t‐test (P < 0.05). Finally, clinical feasibility was investigated in a patient with interstitial fibrosis. Results: Simulation and phantom studies showed up to 67% improvement in SNR and reduced blurring for short T 2* species using all three optimizations. In vivo images showed decreased artifacts and improved lung tissue and airway visualization both qualitatively and quantitatively. Conclusion: The use of limited field‐of‐view excitation, variable readout gradients, and radial oversampling significantly improve the technical quality of 3D radial ultrashort echo time lung images. Magn Reson Med 70:1241–1250, 2013. © 2012 Wiley Periodicals, Inc.

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Metadata

Authors
Johnson, K. M., Fain, S. B., Schiebler, M. L., & Nagle, S.
Venue
Magnetic Resonance in Medicine
Publisher
Wiley
Published
2012-12-04
Volume
70
Issue
5
Pages
1241-1250
ISSN
  • 0740-3194 (ISSN-L)
  • 1522-2594
OpenAlex
W1925481226
Cited by
322
References
21
FWCI
11.57
Type
journal article
Language
en
Open access
bronze

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CoChat. (2026). Citation check: Optimized 3D ultrashort echo time pulmonary MRI. https://app.cochat.ai/papers/10.1002/mrm.24570
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Johnson, K. M., Fain, S. B., Schiebler, M. L., & Nagle, S. (2013). Optimized 3D ultrashort echo time pulmonary MRI. Magnetic Resonance in Medicine. https://doi.org/10.1002/mrm.24570

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