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Cited by 490

The DOI matches its Crossref record; 41 of the 41 references it cites were found in a registry or an index.

Risk factors and outcomes of maternal obesity and excessive weight gain during pregnancy

Gaillard, Romy, Durmuş, Büşra, Hofman, Albert, Mackenbach, Johan P., Steegers, Eric A.P., Jaddoe, Vincent W.V.·2013·Obesity
DOI 10.1002/oby.20088
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Abstract

Objective: The prevalence of overweight and obesity among women of reproductive age is increasing. We aimed to determine risk factors and maternal, fetal and childhood consequences of maternal obesity and excessive gestational weight gain. Design and Methods: The study was embedded in a population‐based prospective cohort study among 6959 mothers and their children. The study was based in Rotterdam, The Netherlands (2001–2005). Results: Maternal lower educational level, lower household income, multiparity, and FTO risk allel were associated with an increased risk of maternal obesity, whereas maternal European ethnicity, nulliparity, higher total energy intake, and smoking during pregnancy were associated with an increased risk of excessive gestational weight gain (all p‐values <0.05). As compared to normal weight, maternal obesity was associated with increased risks of gestational hypertension (OR 6.31 (95% CI 4.30, 9.26)), preeclampsia (OR (3.61, (95% CI 2.04, 6.39)), gestational diabetes (OR 6.28 (95%CI 3.01, 13.06)), caesarean delivery (OR 1.91 (95% CI 1.46, 2.50)), delivering large size for gestational age infants (OR 2.97 (95% CI 2.16, 4.08)), and childhood obesity (OR 5.02 (95% CI:2.97, 8.45)). Weaker associations of excessive gestational weight gain with maternal, fetal and childhood outcomes were observed, with the strongest effects for first trimester weight gain. Conclusions: Our study shows that maternal obesity and excessive weight gain during pregnancy are associated with socio‐demographic, lifestyle, and genetic factors and with increased risks of adverse maternal, fetal and childhood outcomes. As compared to prepregnancy overweight and obesity, excessive gestational weight gain has a limited influence on adverse pregnancy outcomes.

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Research works printed but not linked: 3

  1. 10.1016/j.ajog.2011.08.020 · doi:10.1016/j.ajog.2011.08.020
  2. 10.1016/j.annepidem.2010.06.009 · doi:10.1016/j.annepidem.2010.06.009
  3. Scholl TO, 1990, Weight gain during pregnancy in adolescence: predictive ability of early weight gain, Obstet Gynecol, 75, 948

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Metadata

Authors
Gaillard, R., Durmuş, B., Hofman, A., Mackenbach, J. P., Steegers, E. A. P., & Jaddoe, V. W. V.
Venue
Obesity
Publisher
Wiley
Published
2013-05
Volume
21
Issue
5
Pages
1046-1055
ISSN
  • 1930-7381 (ISSN-L)
  • 1930-739X
DOI
10.1002/oby.20088
OpenAlex
W2119347204
Cited by
490
References
41
FWCI
35.67
Type
journal article
Language
en
Open access
closed
Licence
onlinelibrary.wiley.com/termsAndConditions#vor (vor, 50 d)
Funders
  • Erasmus Medical Center, Rotterdam, the Erasmus University Rotterdam
  • Netherlands Organization for Health Research and Development (90700303, 916.10159)
  • Netherlands Organisation for Scientific Research
  • Ministry of Health, Welfare and Sport, and the Ministry of Youth and Families

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