The P harmacologic and C linical E ffects of M edical C annabis

Isolation, Structure, and Partial Synthesis of an Active Constituent of Hashish

Gaoni, Y., & Mechoulam, R. (1964) · Journal of the American Chemical Society · doi:10.1021/ja01062a046 · Cited by 2,407 · see citing works

International Union of Basic and Clinical Pharmacology. LXXIX. Cannabinoid Receptors and Their Ligands: Beyond CB1 and CB2

Pertwee, R. G., Howlett, A. C., Abood, M. E., Alexander, S. P. H., Marzo, V. D., Elphick, M. R., Greasley, P. J., Hansen, H. S., Kunos, G., Mackie, K., et al. (2010) · Pharmacological Reviews · doi:10.1124/pr.110.003004 · Cited by 1,610 · see citing works

Role of Endogenous Cannabinoids in Synaptic Signaling

Freund, T. F., Katona, I., & Piomelli, D. (2003) · Physiological Reviews · doi:10.1152/physrev.00004.2003 · Cited by 1,567 · see citing works

Goldfrank's Toxicologic Emergencies.

(1986) · Annals of Internal Medicine · doi:10.7326/0003-4819-105-2-323 · Cited by 1,279 · see citing works

Adverse health effects of non-medical cannabis use

Hall, W., & Degenhardt, L. (2009) · The Lancet · doi:10.1016/s0140-6736(09)61037-0 · Cited by 1,134 · see citing works

Goldfrank’s Toxicologic Emergencies

Rusyniak, D. E. (2007) · JAMA · doi:10.1001/jama.297.8.894 · Cited by 876 · see citing works

Cannabinoids for treatment of spasticity and other symptoms related to multiple sclerosis (CAMS study): multicentre randomised placebo-controlled trial

Zajicek, J., Fox, P., Sanders, H., Wright, D., Vickery, J., Nunn, A., & Thompson, A. (2003) · The Lancet · doi:10.1016/s0140-6736(03)14738-1 · Cited by 827 · see citing works

Cannabinoid pharmacology: the first 66 years

Pertwee, R. G. (2006) · British Journal of Pharmacology · doi:10.1038/sj.bjp.0706406 · Cited by 783 · see citing works

Randomized, controlled trial of cannabis-based medicine in central pain in multiple sclerosis

Rog, D. J., Nurmikko, T. J., Friede, T., & Young, C. A. (2005) · Neurology · doi:10.1212/01.wnl.0000176753.45410.8b · Cited by 679 · see citing works

Cannabis in painful HIV-associated sensory neuropathy: A randomized placebo-controlled trial

Abrams, D. I., Jay, C. A., Shade, S. B., Vizoso, H., Reda, H., Press, S., Kelly, M. E., Rowbotham, M. C., & Petersen, K. L. (2007) · Neurology · doi:10.1212/01.wnl.0000253187.66183.9c · Cited by 598 · see citing works

Do cannabis-based medicinal extracts have general or specific effects on symptoms in multiple sclerosis? A double-blind, randomized, placebo-controlled study on 160 patients

Wade, D. T., Makela, P., Robson, P., House, H., & Bateman, C. (2004) · Multiple Sclerosis Journal · doi:10.1191/1352458504ms1082oa · Cited by 589 · see citing works

Cannabinoids control spasticity and tremor in a multiple sclerosis model

Baker, D., Pryce, G., Croxford, J., Brown, P., Pertwee, R., Huffman, J. W., & Layward, L. (2000) · Nature · doi:10.1038/35003583 · Cited by 546 · see citing works

Acute Cannabinoids Impair Working Memory through Astroglial CB1 Receptor Modulation of Hippocampal LTD

Han, J., Kesner, P., Metna-Laurent, M., Duan, T., Xu, L., Georges, F., Koehl, M., Abrous, D. N., Mendizabal-Zubiaga, J., Grandes, P., et al. (2012) · Cell · doi:10.1016/j.cell.2012.01.037 · Cited by 514 · see citing works

Cannabidiol: An Overview of Some Pharmacological Aspects

Mechoulam, R., Parker, L. A., & Gallily, R. (2002) · The Journal of Clinical Pharmacology · doi:10.1002/j.1552-4604.2002.tb05998.x · Cited by 511 · see citing works

Involvement of CB1 cannabinoid receptors in emotional behaviour

Martín, M., Ledent, C. A., Parmentier, M., Maldonado, R. J., & Valverde, O. (2002) · Psychopharmacology · doi:10.1007/s00213-001-0946-5 · Cited by 507 · see citing works

Does the cannabinoid dronabinol reduce central pain in multiple sclerosis? Randomised double blind placebo controlled crossover trial

Svendsen, K. B., Jensen, T. S., & Bach, F. W. (2004) · BMJ · doi:10.1136/bmj.38149.566979.ae · Cited by 500 · see citing works

Regional Brain Abnormalities Associated With Long-term Heavy Cannabis Use

Yücel, M., Solowij, N., Respondek, C., Whittle, S., Fornito, A., Pantelis, C., & Lubman, D. I. (2008) · Archives of General Psychiatry · doi:10.1001/archpsyc.65.6.694 · Cited by 495 · see citing works

A randomized, double-blind, placebo-controlled, parallel-group, enriched-design study of nabiximols* (Sativex^®), as add-on therapy, in subjects with refractory spasticity caused by multiple sclerosis: Sativex for refractory spasticity in MS

Novotna, A., Mares, J., Ratcliffe, S., Novakova, I., Vachova, M., Zapletalova, O., Gasperini, C., Pozzilli, C., Cefaro, L., Comi, G., et al. (2011) · European Journal of Neurology · doi:10.1111/j.1468-1331.2010.03328.x · Cited by 475 · see citing works

Plasma delta-9-tetrahydrocannabinol concentrations and clinical effects after oral and intravenous administration and smoking

Ohlsson, A., Lindgren, J. ‐., Wahlén, A., Agurell, S., Hollister, L. E., & Gillespie, H. K. (1980) · Clinical Pharmacology & Therapeutics · doi:10.1038/clpt.1980.181 · Cited by 475 · see citing works

Smoked Medicinal Cannabis for Neuropathic Pain in HIV: A Randomized, Crossover Clinical Trial

Ellis, R. J., Toperoff, W., Vaida, F., van den Brande, G., Gonzales, J., Gouaux, B., Bentley, H., & Atkinson, J. H. (2009) · Neuropsychopharmacology · doi:10.1038/npp.2008.120 · Cited by 461 · see citing works

Smoked cannabis for chronic neuropathic pain: a randomized controlled trial

Ware, M. A., Wang, T., Shapiro, S., Robinson, A., Ducruet, T., Huynh, T., Gamsa, A., Bennett, G. J., & Collet, J.-P. (2010) · Canadian Medical Association Journal · doi:10.1503/cmaj.091414 · Cited by 450 · see citing works

A preliminary controlled study to determine whether whole-plant cannabis extracts can improve intractable neurogenic symptoms

Wade, D. T., Robson, P., House, H., Makela, P., & Aram, J. (2003) · Clinical Rehabilitation · doi:10.1191/0269215503cr581oa · Cited by 441 · see citing works

Preliminary assessment of the efficacy, tolerability and safety of a cannabis-based medicine (Sativex) in the treatment of pain caused by rheumatoid arthritis

Blake, D. R., Robson, P., Ho, M., Jubb, R. W., & McCabe, C. S. (2006) · Rheumatology · doi:10.1093/rheumatology/kei183 · Cited by 433 · see citing works

Sativex successfully treats neuropathic pain characterised by allodynia: A randomised, double-blind, placebo-controlled clinical trial

Nurmikko, T. J., Serpell, M. G., Hoggart, B., Toomey, P. J., Morlion, B. J., & Haines, D. (2007) · Pain · doi:10.1016/j.pain.2007.08.028 · Cited by 431 · see citing works

Marijuana and medicine: assessing the science base

(1999) · Choice Reviews Online · doi:10.5860/choice.37-2206 · Cited by 410 · see citing works

THE ENDOCANNABINOID SYSTEM: PHYSIOLOGY AND PHARMACOLOGY

de Fonseca, F. R., del Arco, I., Bermúdez‐Silva, F. J., Bilbao, A., Cippitelli, A., & Navarro, M. (2004) · Alcohol and Alcoholism · doi:10.1093/alcalc/agh110 · Cited by 409 · see citing works

Pharmacokinetics and metabolism of delta 1-tetrahydrocannabinol and other cannabinoids with emphasis on man.

Agurell, S., Halldin, M., Lindgren, J. E., Ohlsson, A., Widman, M., Gillespie, H., & Hollister, L. (1986) · Pharmacological Reviews · doi:10.1016/s0031-6997(25)06861-9 · Cited by 406 · cited 4× · see citing works

An archaeological and historical account of cannabis in China

Li, H. (1973) · Economic Botany · doi:10.1007/bf02862859 · Cited by 397 · see citing works

Being stoned: a review of self‐reported cannabis effects

Green, B., Kavanagh, D. J., & Young, R. M. (2003) · Drug and Alcohol Review · doi:10.1080/09595230310001613976 · Cited by 390 · see citing works

Nabilone for the treatment of pain in fibromyalgia.

Skrabek, R. Q., Galimova, L., Ethans, K., & Perry, D. (2008) · The Journal of Pain · doi:10.1016/j.jpain.2007.09.002 · Cited by 384 · cited 1× · see citing works

The Chronic Effects of Cannabis on Memory in Humans: A Review

Solowij, N., & Battisti, R. A. (2008) · Current Drug Abuse Reviews · doi:10.2174/1874473710801010081 · Cited by 380 · see citing works

Randomized controlled trial of cannabis‐based medicine in spasticity caused by multiple sclerosis

Collin, C., Davies, P., Mutiboko, I. K., Ratcliffe, S. H., & for the Sativex Spasticity in MS Study Group (2007) · European Journal of Neurology · doi:10.1111/j.1468-1331.2006.01639.x · Cited by 379 · see citing works

The analgesic properties of delta‐9‐tetrahydrocannabinol and codeine

Noyes, R., Brunk, S. F., Avery, D. H., & Canter, A. (1975) · Clinical Pharmacology & Therapeutics · doi:10.1002/cpt197518184 · Cited by 378 · see citing works

Adverse effects of medical cannabinoids: a systematic review

Wang, T., Collet, J.-P., Shapiro, S., & Ware, M. A. (2008) · Canadian Medical Association Journal · doi:10.1503/cmaj.071178 · Cited by 357 · see citing works

Metabolism, disposition, and kinetics of delta-9-tetrahydrocannabinol in men and women

Wall, M. E., Sadler, B. M., Brine, D. R., Taylor, H. L., & Perez‐Reyes, M. (1983) · Clinical Pharmacology & Therapeutics · doi:10.1038/clpt.1983.179 · Cited by 346 · see citing works

Cannabinoids in multiple sclerosis (CAMS) study: safety and efficacy data for 12 months follow up

Zajicek, J. P. (2005) · Journal of Neurology, Neurosurgery & Psychiatry · doi:10.1136/jnnp.2005.070136 · Cited by 335 · see citing works

A randomized, placebo-controlled, crossover trial of cannabis cigarettes in neuropathic pain

Wilsey, B., Marcotte, T., Tsodikov, A., Millman, J., Bentley, H., Gouaux, B., & Fishman, S. (2008) · The Journal of Pain · doi:10.1016/j.jpain.2007.12.010 · Cited by 327 · see citing works

Who Are Medical Marijuana Patients? Population Characteristics from Nine California Assessment Clinics

Reinarman, C., Nunberg, H., Lanthier, F., & Heddleston, T. (2011) · Journal of Psychoactive Drugs · doi:10.1080/02791072.2011.587700 · Cited by 290 · see citing works

Analgesic Effect of Delta‐9‐Tetrahydrocannabinol

Noyes, R., Brunk, S. F., BARAM, D. A., & Canter, A. (1975) · The Journal of Clinical Pharmacology · doi:10.1002/j.1552-4604.1975.tb02348.x · Cited by 272 · see citing works

Treatments for spasticity and pain in multiple sclerosis: a systematic review

Beard, S. M., Hunn, A., & Wight, J. (2003) · Health Technology Assessment · doi:10.3310/hta7400 · Cited by 266 · see citing works

Vaporization as a Smokeless Cannabis Delivery System: A Pilot Study

Abrams, D. I., Vizoso, H., Shade, S., Jay, C., Kelly, M., & Benowitz, N. (2007) · Clinical pharmacology and therapy · doi:10.1038/sj.clpt.6100200 · Cited by 263 · see citing works

Pharmacological Treatment of Painful HIV-Associated Sensory Neuropathy: A Systematic Review and Meta-Analysis of Randomised Controlled Trials

Phillips, T., Cherry, C. L., Cox, S., Marshall, S. J., & Rice, A. S. C. (2010) · PLoS ONE · doi:10.1371/journal.pone.0014433 · Cited by 257 · see citing works

Dose-dependent Effects of Smoked Cannabis on Capsaicin-induced Pain and Hyperalgesia in Healthy Volunteers

Wallace, M. S., Schulteis, G., Atkinson, J. H., Wolfson, T. J., Lazzaretto, D., Bentley, H. A., Gouaux, B. D., & ABRAMSON, I. S. (2007) · Anesthesiology · doi:10.1097/01.anes.0000286986.92475.b7 · Cited by 250 · see citing works

Efficacy, safety and tolerability of an orally administered cannabis extract in the treatment of spasticity in patients with multiple sclerosis: a randomized, double-blind, placebo-controlled, crossover study

Vaney, C., Heinzel-Gutenbrunner, M., Jobin, P., Tschopp, F., Gattlen, B., Hagen, U., Schnelle, M., & Reif, M. (2004) · Multiple Sclerosis · doi:10.1191/1352458504ms1048oa · Cited by 239 · see citing works

Adolescent cannabis use and psychosis: epidemiology and neurodevelopmental models

Malone, D. T., Hill, M. N., & Rubino, T. (2010) · British Journal of Pharmacology · doi:10.1111/j.1476-5381.2010.00721.x · Cited by 237 · see citing works

Medial temporal structures and memory functions in adolescents with heavy cannabis use

Ashtari, M., Avants, B., Cyckowski, L. L., Cervellione, K. L., Roofeh, D., Cook, P. A., Gee, J. C., Sevy, S. M., & Kumra, S. (2011) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2011.01.004 · Cited by 237 · see citing works

Systematic Review and Meta-analysis of Cannabis Treatment for Chronic Pain

Martín-Sánchez, E., Furukawa, T. A., Taylor, J., & Martín, J. L. R. (2009) · Pain Medicine · doi:10.1111/j.1526-4637.2009.00703.x · Cited by 227 · see citing works

Cannabis with high cannabidiol content is associated with fewer psychotic experiences

Schubart, C. D., Sommer, I. E., van Gastel, W. A., Goetgebuer, R., Kahn, R. S., & Boks, M. P. (2011) · Schizophrenia Research · doi:10.1016/j.schres.2011.04.017 · Cited by 227 · see citing works

Cannabis Use and the Course of Schizophrenia: 10-Year Follow-Up After First Hospitalization

Foti, D., Kotov, R., Guey, L. T., & Bromet, E. J. (2010) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2010.09020189 · Cited by 224 · see citing works

The analgesic effect of oral delta-9-tetrahydrocannabinol (THC), morphine, and a THC-morphine combination in healthy subjects under experimental pain conditions

Naef, M., Curatolo, M., Petersen-Felix, S., Arendt-Nielsen, L., Zbinden, A., & Brenneisen, R. (2003) · Pain · doi:10.1016/s0304-3959(03)00163-5 · Cited by 209 · see citing works

Comparison of subjective, pharmacokinetic, and physiologic effects of marijuana smoked as joints and blunts

Cooper, Z. D., & Haney, M. (2009) · Drug and Alcohol Dependence · doi:10.1016/j.drugalcdep.2009.01.023 · Cited by 189 · see citing works

Oromucosal Δ9-tetrahydrocannabinol/cannabidiol for neuropathic pain associated with multiple sclerosis: An uncontrolled, open-label, 2-year extension trial

ROG, D., NURMIKKO, T., & YOUNG, C. (2007) · Clinical Therapeutics · doi:10.1016/j.clinthera.2007.09.013 · Cited by 187 · see citing works

Lack of analgesic efficacy of oral δ-9-tetrahydrocannabinol in postoperative pain

Buggy, D. J., Toogood, L., Maric, S., Sharpe, P., Lambert, D. G., & Rowbotham, D. J. (2003) · Pain · doi:10.1016/s0304-3959(03)00331-2 · Cited by 184 · see citing works

Medicinal use of cannabis in the United States: Historical perspectives, current trends, and future directions

Aggarwal, S. K., Carter, G. T., Sullivan, M. D., ZumBrunnen, C., Morrill, R. L., & Mayer, J. D. (2018) · Journal of Opioid Management · doi:10.5055/jom.2009.0016 · Cited by 183 · see citing works

Delta-9-THC in the Treatment of Spasticity Associated with Multiple Sclerosis

Ungerleider, J. T., Andyrsiak, T., Fairbanks, L. A., Ellison, G. W., & Myers, L. W. (1988) · Advances in Alcohol & Substance Abuse · doi:10.1300/j251v07n01_04 · Cited by 165 · see citing works

Clinical and cost-effectiveness of capecitabine and tegafur with uracil for the treatment of metastatic colorectal cancer: systematic review and economic evaluation

Ward, S. E., Kaltenthaler, E., Cowan, J., & Brewer, N. (2003) · Health Technology Assessment · doi:10.3310/hta7320 · Cited by 162 · see citing works

Effects of nabilone, a synthetic cannabinoid, on postoperative pain

Beaulieu, P. (2006) · Canadian Journal of Anesthesia/Journal canadien d anesthésie · doi:10.1007/bf03022793 · Cited by 161 · see citing works

Meta-analysis of the efficacy and safety of Sativex (nabiximols), on spasticity in people with multiple sclerosis

Wade, D. T., Collin, C., Stott, C. G., & Duncombe, P. (2010) · Multiple Sclerosis Journal · doi:10.1177/1352458510367462 · Cited by 151 · see citing works

Cannabis Use in Patients with Fibromyalgia: Effect on Symptoms Relief and Health-Related Quality of Life

Fiz, J., Durán, M., Capellà, D., Abelló, J. C., & Farré, M. (2011) · PLoS ONE · doi:10.1371/journal.pone.0018440 · Cited by 132 · see citing works

Pain relief with oral cannabinoids in familial Mediterranean fever

Holdcroft, A., Smith, M., Jacklin, A., Hodgson, H. J. F., Smith, B., Newton, M., & Evans, F. J. (1997) · Anaesthesia · doi:10.1111/j.1365-2044.1997.139-az0132.x · Cited by 129 · see citing works

Biomarkers for the effects of cannabis and THC in healthy volunteers

Zuurman, L., Ippel, A. E., Moin, E., & van Gerven, J. (2008) · British Journal of Clinical Pharmacology · doi:10.1111/j.1365-2125.2008.03329.x · Cited by 123 · see citing works

Toxicity of short-term administration of cannabinoids to rhesus monkeys

Rosenkrantz, H., Fleischman, R. W., & Grant, R. J. (1981) · Toxicology and Applied Pharmacology · doi:10.1016/0041-008x(81)90122-8 · Cited by 112 · see citing works

Cannabis and Its Derivatives: Review of Medical Use

Leung, L. (2011) · The Journal of the American Board of Family Medicine · doi:10.3122/jabfm.2011.04.100280 · Cited by 102 · see citing works

Effects of cannabis on cognitive function in patients with multiple sclerosis

Honarmand, K., Tierney, M. C., O'Connor, P. W., & Feinstein, A. (2011) · Neurology · doi:10.1212/wnl.0b013e318212ab0c · Cited by 99 · see citing works

Modelling of the concentration—effect relationship of THC on central nervous system parameters and heart rate — insight into its mechanisms of action and a tool for clinical research and development of cannabinoids

Strougo, A., Zuurman, L., Roy, C., Pinquier, J. L., van Gerven, J., Cohen, A., & Schoemaker, R. C. (2008) · Journal of Psychopharmacology · doi:10.1177/0269881108089870 · Cited by 83 · see citing works

An overview of systematic reviews on cannabis and psychosis: Discussing apparently conflicting results

Minozzi, S., Davoli, M., Bargagli, A. M., Amato, L., Vecchi, S., & Perucci, C. A. (2010) · Drug and Alcohol Review · doi:10.1111/j.1465-3362.2009.00132.x · Cited by 79 · see citing works

Medical marijuana and the developing role of the pharmacist

Seamon, M. J., Fass, J. A., Maniscalco-Feichtl, M., & Abu-Shraie, N. (2007) · American Journal of Health-System Pharmacy · doi:10.2146/ajhp060471 · Cited by 76 · see citing works

Ingestion of cannabis

Macnab, A. J., ANDERSON, E., & Susak, L. E. (1989) · Pediatric Emergency Care · doi:10.1097/00006565-198912000-00010 · Cited by 74 · see citing works

Cannabinoid–hormone interactions in the regulation of motivational processes

López, H. H. (2009) · Hormones and Behavior · doi:10.1016/j.yhbeh.2009.10.005 · Cited by 67 · see citing works

The intersection between cannabis and cancer in the United States

Bowles, D. W., O’Bryant, C. L., Camidge, D. R., & Jimeno, A. (2011) · Critical Reviews in Oncology/Hematology · doi:10.1016/j.critrevonc.2011.09.008 · Cited by 66 · see citing works

A Randomized, Double-Blinded, Crossover Pilot Study Assessing the Effect of Nabilone on Spasticity in Persons With Spinal Cord Injury

Pooyania, S., Ethans, K., Szturm, T., Casey, A., & Perry, D. (2010) · Archives of Physical Medicine and Rehabilitation · doi:10.1016/j.apmr.2009.12.025 · Cited by 64 · see citing works

Cerebellar grey-matter deficits, cannabis use and first-episode schizophrenia in adolescents and young adults

Cohen, M. A., Rasser, P. E., Peck, G., Carr, V. J., Ward, P. B., Thompson, P. M., Johnston, P., Baker, A., & Schall, U. (2011) · The International Journal of Neuropsychopharmacology · doi:10.1017/s146114571100068x · Cited by 59 · see citing works

Examining the roles of cannabinoids in pain and other therapeutic indications: a review

Turcotte, D., Dorze, J.-A. L., Esfahani, F., Frost, E. E., Gomori, A. J., & Namaka, M. (2009) · Expert Opinion on Pharmacotherapy · doi:10.1517/14656560903413534 · Cited by 58 · see citing works

Prolonged Coma in a Child Due to Hashish Ingestion with Quantitation of THC Metabolites in Urine

Carstairs, S. D., Fujinaka, M. K., Keeney, G. E., & Ly, B. T. (2010) · Journal of Emergency Medicine · doi:10.1016/j.jemermed.2010.05.032 · Cited by 53 · see citing works

A possible role for the endocannabinoid system in the neurobiology of depression

Serra, G., & Fratta, W. (2007) · Clinical Practice and Epidemiology in Mental Health · doi:10.1186/1745-0179-3-25 · Cited by 51 · see citing works

Intoxication from Accidental Marijuana Ingestion

Weinberg, D. H., Lande, A. E., HILTON, N., & Kerns, D. L. (1983) · PEDIATRICS · doi:10.1542/peds.71.5.848 · Cited by 47 · see citing works

“But my Doctor Recommended Pot”: Medical Marijuana and the Patient–Physician Relationship

Nussbaum, A. M., Boyer, J. A., & Kondrad, E. C. (2011) · Journal of General Internal Medicine · doi:10.1007/s11606-011-1840-4 · Cited by 46 · see citing works

The Office of Applied Studies

(2005) · PsycEXTRA Dataset · doi:10.1037/e434182005-001 · Cited by 35 · see citing works

A case series of marijuana exposures in pediatric patients less than 5 years of age

Wang, G. S., Narang, S. K., Wells, K. M., & Chuang, R. (2011) · Child Abuse & Neglect · doi:10.1016/j.chiabu.2011.03.012 · Cited by 28 · see citing works

Medical Marijuana Use and Suicide Attempt in a Patient With Major Depressive Disorder

Nussbaum, A. M., Thurstone, C., & Binswanger, I. A. (2011) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2011.10121769 · Cited by 19 · see citing works

Neurocognitive functions of heavy cannabis using schizophrenia patients

Lev‐Ran, S., Segev, A., Braw, Y., & Levkovitz, Y. (2011) · European Psychiatry · doi:10.1016/j.eurpsy.2011.04.010 · Cited by 17 · see citing works

IS THERE A CAUSAL LINKAGE BETWEEN CANNABIS USE AND INCREASED RISKS OF PSYCHOTIC SYMPTOMS?

Fergusson, D. M. (2010) · Addiction · doi:10.1111/j.1360-0443.2010.02959.x · Cited by 7 · see citing works

Treatment Episode Data Set -- Admissions (TEDS-A), 2008

United States Department of Health and Human Services. Substance Abuse and Mental Health Services Administration. Office of Applied Studies (2010) · ICPSR Data Holdings · doi:10.3886/icpsr27241 · Cited by 3 · see citing works

Modulating ROS to overcome multidrug resistance in cancer

Cui, Q., Wang, J., Assaraf, Y. G., Ren, L., Gupta, P., Wei, L., Ashby, C. R., Yang, D., & Chen, Z. (2018) · Drug Resistance Updates · doi:10.1016/j.drup.2018.11.001 · Cited by 664 · see citing works

Cannabidiol: State of the art and new challenges for therapeutic applications

Pisanti, S., Malfitano, A. M., Ciaglia, E., Lamberti, A., Ranieri, R., Cuomo, G., Abate, M., Faggiana, G., Proto, M., Fiore, D., et al. (2017) · Pharmacology & Therapeutics · doi:10.1016/j.pharmthera.2017.02.041 · Cited by 625 · see citing works

Do medical marijuana laws reduce addictions and deaths related to pain killers?

Powell, D., Pacula, R. L., & Jacobson, M. (2018) · Journal of Health Economics · doi:10.1016/j.jhealeco.2017.12.007 · Cited by 347 · see citing works

Pharmacology of Medical Cannabis

Amin, M. R., & Ali, D. W. (2019) · Advances in experimental medicine and biology · doi:10.1007/978-3-030-21737-2_8 · Cited by 290 · see citing works

CB2 Cannabinoid Receptors as a Therapeutic Target—What Does the Future Hold?

Dhopeshwarkar, A., & Mackie, K. (2014) · Molecular Pharmacology · doi:10.1124/mol.114.094649 · Cited by 254 · see citing works

Medicinal Properties of Cannabinoids, Terpenes, and Flavonoids in Cannabis, and Benefits in Migraine, Headache, and Pain: An Update on Current Evidence and Cannabis Science

Baron, E. P. (2018) · Headache The Journal of Head and Face Pain · doi:10.1111/head.13345 · Cited by 256 · see citing works

Pharmaceutical and biomedical analysis of cannabinoids: A critical review

Citti, C., Braghiroli, D., Vandelli, M. A., & Cannazza, G. (2017) · Journal of Pharmaceutical and Biomedical Analysis · doi:10.1016/j.jpba.2017.06.003 · Cited by 254 · see citing works

Clinicians’ Guide to Cannabidiol and Hemp Oils

VanDolah, H. J., Bauer, B. A., & Mauck, K. F. (2019) · Mayo Clinic Proceedings · doi:10.1016/j.mayocp.2019.01.003 · Cited by 239 · see citing works

The Effect of Medicinal Cannabis on Pain and Quality-of-Life Outcomes in Chronic Pain: A Prospective Open-label Study

Haroutounian, S., Ratz, Y., Ginosar, Y., Furmanov, K., Saifi, F., Meidan, R., & Davidson, E. (2016) · The Clinical Journal of Pain · doi:10.1097/ajp.0000000000000364 · Cited by 234 · see citing works

Cannabis in cancer care

Abrams, D., & Guzmán, M. (2015) · Clinical Pharmacology & Therapeutics · doi:10.1002/cpt.108 · Cited by 217 · see citing works

The Effectiveness of Topical Cannabidiol Oil in Symptomatic Relief of Peripheral Neuropathy of the Lower Extremities

Xu, D. H., Cullen, B. D., Tang, M. Y., & Fang, Y. (2019) · Current Pharmaceutical Biotechnology · doi:10.2174/1389201020666191202111534 · Cited by 209 · see citing works

New horizons for newborn brain protection: enhancing endogenous neuroprotection

Hassell, K. J., Ezzati, M., Alconada, D. A., Hausenloy, D. J., & Robertson, N. J. (2015) · Archives of Disease in Childhood Fetal & Neonatal · doi:10.1136/archdischild-2014-306284 · Cited by 202 · see citing works

Quality Traits of “Cannabidiol Oils”: Cannabinoids Content, Terpene Fingerprint and Oxidation Stability of European Commercially Available Preparations

Pavlović, R., Nenna, G., Calvi, L., Panseri, S., Borgonovo, G., Giupponi, L., Cannazza, G., & Giorgi, A. (2018) · Molecules · doi:10.3390/molecules23051230 · Cited by 198 · see citing works

Synthetic and Non-synthetic Cannabinoid Drugs and Their Adverse Effects-A Review From Public Health Prospective

Cohen, K., & Weinstein, A. M. (2018) · Frontiers in Public Health · doi:10.3389/fpubh.2018.00162 · Cited by 197 · see citing works

Tasty THC: Promises and Challenges of Cannabis Edibles

RTI International, D., Barrus, D. G., Giombi, K., Cates, S. C., Gourdet, C., Peiper, N. C., Novak, S. P., Lefever, T. W., & Wiley, J. L. (2016) · doi:10.3768/rtipress.2016.op.0035.1611 · Cited by 198 · see citing works

The Endocannabinoid System, Cannabinoids, and Pain

Fine, P. G., & Rosenfeld, M. J. (2013) · Rambam Maimonides Medical Journal · doi:10.5041/rmmj.10129 · Cited by 203 · see citing works

Methods for quantification of cannabinoids: a narrative review

Lazarjani, M. P., Torres, S., Hooker, T., Fowlie, C., Young, O. A., & Seyfoddin, A. (2020) · Journal of Cannabis Research · doi:10.1186/s42238-020-00040-2 · Cited by 159 · see citing works

Medicinal cannabis: Principal cannabinoids concentration and their stability evaluated by a high performance liquid chromatography coupled to diode array and quadrupole time of flight mass spectrometry method.

Citti, C., Ciccarella, G., Braghiroli, D., Parenti, C., Vandelli, M., & Cannazza, G. (2016) · Journal of Pharmaceutical and Biomedical Analysis · doi:10.1016/j.jpba.2016.05.033 · Cited by 139 · see citing works

Monoglyceride lipase as a drug target: At the crossroads of arachidonic acid metabolism and endocannabinoid signaling

Grabner, G. F., Zimmermann, R., Schicho, R., & Taschler, U. (2017) · Pharmacology & Therapeutics · doi:10.1016/j.pharmthera.2017.02.033 · Cited by 151 · see citing works

Differences in receptor binding affinity of several phytocannabinoids do not explain their effects on neural cell cultures

Rosenthaler, S., Pöhn, B., Kolmanz, C., Nguyen, C. H., Krewenka, C., Huber, A., Kranner, B., Rausch, W., & Moldzio, R. (2014) · Neurotoxicology and Teratology · doi:10.1016/j.ntt.2014.09.003 · Cited by 148 · see citing works

Cannabis in Eurasia: origin of human use and Bronze Age trans-continental connections

Long, T., Wagner, M., Demske, D., Leipe, C., & Tarasov, P. E. (2016) · Vegetation History and Archaeobotany · doi:10.1007/s00334-016-0579-6 · Cited by 137 · see citing works

Comprehensive quality evaluation of medical Cannabis sativa L. inflorescence and macerated oils based on HS-SPME coupled to GC–MS and LC-HRMS (q-exactive orbitrap®) approach

Calvi, L., Pentimalli, D., Panseri, S., Giupponi, L., Gelmini, F., Beretta, G., Vitali, D., Bruno, M., Zilio, E., Pavlović, R., et al. (2017) · Journal of Pharmaceutical and Biomedical Analysis · doi:10.1016/j.jpba.2017.11.073 · Cited by 140 · see citing works

Safety and Toxicology of Cannabinoids

Sachs, J., McGlade, E., & Yurgelun-Todd, D. A. (2015) · Neurotherapeutics · doi:10.1007/s13311-015-0380-8 · Cited by 127 · see citing works

The effects of cannabinoid administration on sleep: a systematic review of human studies

Gates, P., Albertella, L., & Copeland, J. (2014) · Sleep Medicine Reviews · doi:10.1016/j.smrv.2014.02.005 · Cited by 127 · see citing works

Terpenes and derivatives as a new perspective for pain treatment: a patent review

Guimarães, A. G., Serafini, M. R., & Quintans‐Júnior, L. J. (2014) · Expert Opinion on Therapeutic Patents · doi:10.1517/13543776.2014.870154 · Cited by 125 · see citing works

Cannabidiol enhances morphine antinociception, diminishes NMDA-mediated seizures and reduces stroke damage via the sigma 1 receptor

Rodríguez-Muñoz, M., Onetti, Y., Cortés‐Montero, E., Garzón, J., & Sánchez‐Blázquez, P. (2018) · Molecular Brain · doi:10.1186/s13041-018-0395-2 · Cited by 122 · see citing works

Isolation, Purification, and Antimicrobial Characterization of Cannabidiolic Acid and Cannabidiol from Cannabis sativa L.

Martinenghi, L. D., Jønsson, R., Lund, T., & Jenssen, H. (2020) · Biomolecules · doi:10.3390/biom10060900 · Cited by 124 · see citing works

The therapeutic potential of cannabinoids for movement disorders

Kluger, B. M., Triolo, P. M., Jones, W. E., & Jankovic, J. J. (2015) · Movement Disorders · doi:10.1002/mds.26142 · Cited by 123 · see citing works

Characterizing the Followers and Tweets of a Marijuana-Focused Twitter Handle

Cavazos‐Rehg, P. A., Krauss, M. J., Grucza, R. A., & Bierut, L. J. (2014) · Journal of Medical Internet Research · doi:10.2196/jmir.3247 · Cited by 118 · see citing works

Trends in registered medical marijuana participation across 13 US states and District of Columbia

Fairman, B. J. (2015) · Drug and Alcohol Dependence · doi:10.1016/j.drugalcdep.2015.11.015 · Cited by 115 · see citing works

Pain and Opioids in Cancer Care: Benefits, Risks, and Alternatives

Bennett, M., Paice, J. A., & Wallace, M. S. (2017) · American Society of Clinical Oncology Educational Book · doi:10.1200/edbk_180469 · Cited by 117 · see citing works

Integrating Cannabis into Clinical Cancer Care

Abrams, D. I. (2016) · Current Oncology · doi:10.3747/co.23.3099 · Cited by 115 · see citing works

Marijuana Use Among Adults 50 Years or Older in the 21st Century

Lloyd, S. L., & Striley, C. W. (2018) · Gerontology and Geriatric Medicine · doi:10.1177/2333721418781668 · Cited by 114 · see citing works

Public opinion and medical cannabis policies: examining the role of underlying beliefs and national medical cannabis policies

Sznitman, S. R., & Bretteville‐Jensen, A. L. (2015) · Harm Reduction Journal · doi:10.1186/s12954-015-0082-x · Cited by 113 · see citing works

Medical Marijuana and Chronic Pain: a Review of Basic Science and Clinical Evidence

Jensen, B., Chen, J. L., Furnish, T. J., & Wallace, M. S. (2015) · Current Pain and Headache Reports · doi:10.1007/s11916-015-0524-x · Cited by 111 · see citing works

Are medical marijuana users different from recreational users? The view from primary care

Roy‐Byrne, P., Maynard, C. C., Bumgardner, K., Krupski, A., Dunn, C. W., West, I. I., Donovan, D. M., Atkins, D. C., & Ries, R. K. (2015) · American Journal on Addictions · doi:10.1111/ajad.12270 · Cited by 103 · see citing works

Medicinal cannabis in Australia, 2016: the Cannabis as Medicine Survey (CAMS-16)

Lintzeris, N., Driels, J., Elias, N., Arnold, J. C., McGregor, I. S., & Allsop, D. J. (2018) · Medical Journal of Australia · doi:10.5694/mja17.01247 · Cited by 101 · see citing works

Therapeutic use of cannabis and cannabinoids: an evidence mapping and appraisal of systematic reviews

Montero‐Oleas, N., Arévalo-Rodríguez, I., Núñez-González, S., Viteri-García, A. A., & Simancas‐Racines, D. (2020) · BMC Complementary Medicine and Therapies · doi:10.1186/s12906-019-2803-2 · Cited by 98 · see citing works

Scientific Opinion on the risks for human health related to the presence of tetrahydrocannabinol (THC) in milk and other food of animal origin

(CONTAM), E. P. O. C. I. T. F. C. (2015) · EFSA Journal · doi:10.2903/j.efsa.2015.4141 · Cited by 98 · see citing works

PTL401, a New Formulation Based on Pro-Nano Dispersion Technology, Improves Oral Cannabinoids Bioavailability in Healthy Volunteers

Atsmon, J., Cherniakov, I., Izgelov, D., Hoffman, A., Domb, A. J., Deutsch, L., Deutsch, F., Heffetz, D., & Sacks, H. (2017) · Journal of Pharmaceutical Sciences · doi:10.1016/j.xphs.2017.12.020 · Cited by 97 · see citing works

Medical cannabis treatment for chronic pain: Outcomes and prediction of response

Aviram, J., Pud, D., Gershoni, T., Schiff‐Keren, B., Ogintz, M., Vulfsons, S., Yashar, T., Adahan, H., Brill, S., Amital, H., et al. (2020) · European Journal of Pain · doi:10.1002/ejp.1675 · Cited by 98 · see citing works

Marijuana and lung diseases

Joshi, M., Joshi, A., & Bartter, T. C. (2014) · Current Opinion in Pulmonary Medicine · doi:10.1097/mcp.0000000000000026 · Cited by 95 · see citing works

Colorado Cannabis Legalization and Its Effect on Emergency Care

Kim, H. S., & Monte, A. A. (2016) · Annals of Emergency Medicine · doi:10.1016/j.annemergmed.2016.01.004 · Cited by 94 · see citing works

Cannabis and Depression

Feingold, D., & Weinstein, A. M. (2020) · Advances in experimental medicine and biology · doi:10.1007/978-3-030-57369-0_5 · Cited by 96 · see citing works

Modulatory effects of cannabinoids on brain neurotransmission

Cohen, K., Weizman, A., & Weinstein, A. M. (2019) · European Journal of Neuroscience · doi:10.1111/ejn.14407 · Cited by 92 · see citing works

Δ9-Tetrahydrocannabivarin (THCV): a commentary on potential therapeutic benefit for the management of obesity and diabetes

Abioye, A. O., Ayodele, O., Marinkovic, A., Patidar, R., Akinwekomi, A., & Sanyaolu, A. O. (2020) · Journal of Cannabis Research · doi:10.1186/s42238-020-0016-7 · Cited by 90 · see citing works

Edible Cannabis–Induced Psychosis: Intoxication and Beyond

Hudak, M., Severn, D. G., & Nordstrom, K. (2015) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2015.15030358 · Cited by 88 · see citing works

A Review of Herbal Therapy in Multiple Sclerosis

Mojaverrostami, S., Bojnordi, M. N., Ghasemi‐Kasman, M., Ebrahimzadeh, M. A., & Hamidabadi, H. G. (2018) · Advanced Pharmaceutical Bulletin · doi:10.15171/apb.2018.066 · Cited by 88 · see citing works

Cannabis and Cannabinoids in Mood and Anxiety Disorders: Impact on Illness Onset and Course, and Assessment of Therapeutic Potential

Botsford, S. L., Yang, S., & George, T. P. (2020) · The American Journal on Addictions · doi:10.1111/ajad.12963 · Cited by 88 · see citing works

Dravet syndrome: an overview.

Anwar, A., Saleem, S., Patel, U. K., Arumaithurai, K., & Malik, P. (2019) · Cureus · doi:10.7759/cureus.5006 · Cited by 83 · see citing works

Pediatric Concerns Due to Expanded Cannabis Use: Unintended Consequences of Legalization

Wang, G. S. (2016) · Journal of Medical Toxicology · doi:10.1007/s13181-016-0552-x · Cited by 83 · see citing works

Marijuana use and maternal experiences of severe nausea during pregnancy in Hawai'i.

Roberson, E. K., Patrick, W. K., & Hurwitz, E. L. (2014) · Europe PMC (PubMed Central) · Cited by 82 · see citing works

TRP Channels as Novel Targets for Endogenous Ligands: Focus on Endocannabinoids and Nociceptive Signalling

Storozhuk, M., & Zholos, A. V. (2017) · Current Neuropharmacology · doi:10.2174/1570159x15666170424120802 · Cited by 80 · see citing works

Genetic tools weed out misconceptions of strain reliability in Cannabis sativa: implications for a budding industry

Schwabe, A. L., & McGlaughlin, M. E. (2019) · Journal of Cannabis Research · doi:10.1186/s42238-019-0001-1 · Cited by 78 · see citing works

Does Cannabis Use Cause Declines in Neuropsychological Functioning? A Review of Longitudinal Studies

González, R., Pacheco‐Colón, I., Duperrouzel, J. C., & Hawes, S. W. (2017) · Journal of the International Neuropsychological Society · doi:10.1017/s1355617717000789 · Cited by 77 · see citing works

Nabilone for the Management of Pain

Tsang, C. C., & Giudice, M. G. (2016) · Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy · doi:10.1002/phar.1709 · Cited by 73 · see citing works

Recent advances in the pharmacological management of acute and chronic pain.

Schug, S. A., & Goddard, C. (2014) · PubMed · doi:10.3978/j.issn.2224-5820.2014.10.02 · Cited by 73 · see citing works

Endocannabinoid System and Migraine Pain: An Update

Greco, R., Demartini, C., Zanaboni, A. M., Piomelli, D., & Tassorelli, C. (2018) · Frontiers in Neuroscience · doi:10.3389/fnins.2018.00172 · Cited by 71 · see citing works

Should Cannabinoids Be Added to Multimodal Pain Regimens After Total Hip and Knee Arthroplasty?

Hickernell, T. R., Lakra, A., Berg, A. R., Cooper, H. J., Geller, J. A., & Shah, R. P. (2018) · The Journal of Arthroplasty · doi:10.1016/j.arth.2018.07.027 · Cited by 68 · see citing works

Rational Urine Drug Monitoring in Patients Receiving Opioids for Chronic Pain: Consensus Recommendations

Argoff, C. E., Alford, D. P., Fudin, J., Adler, J. A., Bair, M. J., Dart, R. C., Gandolfi, R., McCarberg, B. H., Stanos, S. P., Gudin, J. A., et al. (2017) · Pain Medicine · doi:10.1093/pm/pnx285 · Cited by 68 · see citing works

Single‐Dose Pharmacokinetics of Oral Cannabidiol Following Administration of PTL101: A New Formulation Based on Gelatin Matrix Pellets Technology

Atsmon, J., Heffetz, D., Deutsch, L., Deutsch, F., & Sacks, H. (2017) · Clinical Pharmacology in Drug Development · doi:10.1002/cpdd.408 · Cited by 67 · see citing works

Effect of Marijuana Use on Outcomes in Traumatic Brain Injury

Nguyen, B. M., Kim, D. S., Bricker, S. D., Bongard, F. S., Neville, A. L., Putnam, B. A., Smith, J., & Plurad, D. S. (2014) · The American Surgeon · doi:10.1177/000313481408001015 · Cited by 66 · see citing works

Effects of peripheral FAAH blockade on NTG-induced hyperalgesia—evaluation of URB937 in an animal model of migraine

Greco, R., Bandiera, T., Mangione, A., Demartini, C., Siani, F., Nappi, G., Sandrini, G., Guijarro, A., Armirotti, A., Piomelli, D., et al. (2015) · Cephalalgia · doi:10.1177/0333102414566862 · Cited by 63 · see citing works

Psychoactive constituents of cannabis and their clinical implications: a systematic review

Casajuana, C., López‐Pelayo, H., Balcells‐Oliveró, M., Colom, J., & Gual, A. (2017) · Adicciones · doi:10.20882/adicciones.858 · Cited by 64 · see citing works

Subcellular specificity of cannabinoid effects in striatonigral circuits

Gómez, E. S., Zottola, A. C. P., Mariani, Y., Desprez, T., Barresi, M., Río, I. B., Muguruza, C., Bon-Jégo, M. L., Julio‐Kalajzić, F., Flynn, R. E., et al. (2021) · Neuron · doi:10.1016/j.neuron.2021.03.007 · Cited by 64 · see citing works

Cannabidiol inhibits the skeletal muscle Nav1.4 by blocking its pore and by altering membrane elasticity

Ghovanloo, M., Choudhury, K., Bandaru, T. S., Fouda, M. A., Rayani, K., Rusinova, R., Phaterpekar, T., Nelkenbrecher, K., Watkins, A. R., Poburko, D., et al. (2021) · The Journal of General Physiology · doi:10.1085/jgp.202012701 · Cited by 61 · see citing works

The Endocannabinoid System and Heart Disease: The Role of Cannabinoid Receptor Type 2

Fulmer, M. L., & Thewke, D. P. (2018) · Cardiovascular & Haematological Disorders - Drug Targets · doi:10.2174/1871529x18666180206161457 · Cited by 63 · see citing works

Unintentional Cannabis Intoxication in Toddlers

Claudet, I., Mouvier, S., Labadie, M., Manin, C., Michard-Lenoir, A.-P., Eyer, D., Dufour, D., & for the Marie-Jeanne Study Group (2017) · PEDIATRICS · doi:10.1542/peds.2017-0017 · Cited by 61 · see citing works

Mid-infrared spectroscopy as process analytical technology tool for estimation of THC and CBD content in Cannabis flowers and extracts

Geškovski, N., Stefkov, G., Gigopulu, O., Stefov, S., Huck, C. W., & Makreski, P. (2021) · Spectrochimica Acta Part A Molecular and Biomolecular Spectroscopy · doi:10.1016/j.saa.2020.119422 · Cited by 60 · see citing works

Tetrahydrocannabinol and cannabidiol medicines for chronic pain and mental health conditions

Henson, J. D., Vitetta, L., & Hall, S. (2022) · Inflammopharmacology · doi:10.1007/s10787-022-01020-z · Cited by 61 · see citing works

Cannabinoids in Pediatrics

Campbell, C. T., Phillips, M. S., & Manasco, K. B. (2017) · The Journal of Pediatric Pharmacology and Therapeutics · doi:10.5863/1551-6776-22.3.176 · Cited by 59 · see citing works

Marijuana Legalization and Youth

Ladegard, K. M., Thurstone, C., & Rylander, M. (2020) · PEDIATRICS · doi:10.1542/peds.2019-2056d · Cited by 60 · see citing works

Patterns of Medical Marijuana Use Among Individuals Sampled from Medical Marijuana Dispensaries in Los Angeles

Grella, C. E., Rodriguez, L., & Kim, T. (2014) · Journal of Psychoactive Drugs · doi:10.1080/02791072.2014.944960 · Cited by 58 · see citing works

A Metabolomic Approach Applied to a Liquid Chromatography Coupled to High‐Resolution Tandem Mass Spectrometry Method (HPLC‐ESI‐HRMS/MS): Towards the Comprehensive Evaluation of the Chemical Composition of Cannabis Medicinal Extracts

Citti, C., Battisti, U. M., Braghiroli, D., Ciccarella, G., Schmid, M. G., Vandelli, M. A., & Cannazza, G. (2017) · Phytochemical Analysis · doi:10.1002/pca.2722 · Cited by 58 · see citing works

Cannabinoids and the kidney: effects in health and disease

Park, F., Potukuchi, P. K., Moradi, H., & Kovesdy, C. P. (2017) · American Journal of Physiology-Renal Physiology · doi:10.1152/ajprenal.00290.2017 · Cited by 56 · see citing works

Comprehensive molecular pharmacology screening reveals potential new receptor interactions for clinically relevant opioids

Olson, K. M., Duron, D. I., Womer, D. E., Fell, R., & Streicher, J. M. (2019) · PLoS ONE · doi:10.1371/journal.pone.0217371 · Cited by 54 · see citing works

Growing medicine: Small-scale cannabis cultivation for medical purposes in six different countries

Hakkarainen, P., Frank, V. A., Barratt, M. J., Dahl, H. V., Decorte, T., Karjalainen, K., Lenton, S. R., Potter, G., & Werse, B. (2014) · International Journal of Drug Policy · doi:10.1016/j.drugpo.2014.07.005 · Cited by 53 · see citing works

Potential Use of Cannabinoids for the Treatment of Pancreatic Cancer

Sharafi, G., He, H. Z., & Nikfarjam, M. (2019) · Journal of Pancreatic Cancer · doi:10.1089/pancan.2018.0019 · Cited by 56 · see citing works

Analgesic efficacy of cannabinoids for acute pain management after surgery: a systematic review and meta-analysis

Abdallah, F. W., Hussain, N., Weaver, T. E., & Brull, R. (2020) · Regional Anesthesia & Pain Medicine · doi:10.1136/rapm-2020-101340 · Cited by 53 · see citing works

Marijuana and alcohol: Evidence using border analysis and retail sales data

Baggio, M., Chong, A. E., & Kwon, S. (2020) · Canadian Journal of Economics/Revue canadienne d économique · doi:10.1111/caje.12437 · Cited by 50 · see citing works

Severe dystonia, cerebellar atrophy, and cardiomyopathy likely caused by a missense mutation in TOR1AIP1

Dorboz, I., Coutelier, M., Bertrand, A., Caberg, J., Elmaleh, M., Lainé, J., Stévanin, G., Bonne, G., Boespflug‐Tanguy, O., & Servais, L. (2014) · Orphanet Journal of Rare Diseases · doi:10.1186/s13023-014-0174-9 · Cited by 51 · see citing works

A preliminary evaluation of the relationship of cannabinoid blood concentrations with the analgesic response to vaporized cannabis

Wilsey, B. L., Deutsch, R., Samara, E. E., Marcotte, T. D., Barnes, A. J., Huestis, M. A., & Le, D. (2016) · Journal of Pain Research · doi:10.2147/jpr.s113138 · Cited by 51 · see citing works

State marijuana laws and opioid overdose mortality

Chihuri, S. T., & Li, G. (2019) · Injury Epidemiology · doi:10.1186/s40621-019-0213-z · Cited by 51 · see citing works

Cannabis Use is Associated with Lower Odds of Prescription Opioid Analgesic Use Among HIV-Infected Individuals with Chronic Pain

Sohler, N., Starrels, J. L., Khalid, L., Bachhuber, M. A., Arnsten, J. H., Nahvi, S., Jost, J. T., & Cunningham, C. O. (2018) · Substance Use & Misuse · doi:10.1080/10826084.2017.1416408 · Cited by 50 · see citing works

Synthetic cannabinoids are substrates and inhibitors of multiple drug-metabolizing enzymes

Kong, T. Y., Kim, J., Kim, D. K., & Lee, H. S. (2018) · Archives of Pharmacal Research · doi:10.1007/s12272-018-1055-x · Cited by 50 · see citing works

Cannabidiol and Sodium Channel Pharmacology: General Overview, Mechanism, and Clinical Implications

Ghovanloo, M., & Ruben, P. C. (2021) · The Neuroscientist · doi:10.1177/10738584211017009 · Cited by 49 · see citing works

A longitudinal examination of the relationship between cannabis use and cognitive function in mid-life adults

McKetin, R., Parasu, P., Cherbuin, N., Eramudugolla, R., & Anstey, K. J. (2016) · Drug and Alcohol Dependence · doi:10.1016/j.drugalcdep.2016.10.022 · Cited by 48 · see citing works

Pharmacy Student Knowledge, Confidence and Attitudes Toward Medical Cannabis and Curricular Coverage

Caligiuri, F. J., Ulrich, E. E., & Welter, K. J. (2018) · American Journal of Pharmaceutical Education · doi:10.5688/ajpe6296 · Cited by 48 · see citing works

Therapeutic potential and safety considerations for the clinical use of synthetic cannabinoids

Sholler, D. J., Huestis, M. A., Amendolara, B., Vandrey, R. G., & Cooper, Z. D. (2020) · Pharmacology Biochemistry and Behavior · doi:10.1016/j.pbb.2020.173059 · Cited by 48 · see citing works

Use and diversion of medical marijuana among adults admitted to inpatient psychiatry

Nussbaum, A. M., Thurstone, C., McGarry, L., Walker, B., & Sabel, A. L. (2014) · The American Journal of Drug and Alcohol Abuse · doi:10.3109/00952990.2014.949727 · Cited by 47 · see citing works

Cannabinoid pharmacology and therapy in gut disorders

Uranga, J. A., Vera, G., & Abalo, R. (2018) · Biochemical Pharmacology · doi:10.1016/j.bcp.2018.07.048 · Cited by 46 · see citing works

Cannabis and the skin

Shao, K., Stewart, C. L., & Grant-Kels, J. M. (2021) · Clinics in Dermatology · doi:10.1016/j.clindermatol.2021.05.006 · Cited by 46 · see citing works

Effective treatment of spasticity using dronabinol in pediatric palliative care

Kuhlen, M., Hoell, J. I., Gagnon, G., Balzer, S., Oommen, P. T., Borkhardt, A., & Janßen, G. (2016) · European Journal of Paediatric Neurology · doi:10.1016/j.ejpn.2016.07.021 · Cited by 46 · see citing works

Current state of evidence of cannabis utilization for treatment of autism spectrum disorders

Agarwal, R., Burke, S. L., & Maddux, M. (2019) · BMC Psychiatry · doi:10.1186/s12888-019-2259-4 · Cited by 46 · see citing works

Cannabinoid Actions on Neural Stem Cells: Implications for Pathophysiology

Rodrigues, R. S., Lourenço, D. M., Paulo, S. L., Mateus, J. M., Ferreira, M. F., Mouro, F. M., Moreira, J. B., Ribeiro, F. F., Sebastião, A. M., & Xapelli, S. (2019) · Molecules · doi:10.3390/molecules24071350 · Cited by 45 · see citing works

Pesticides and trace elements in cannabis: Analytical and environmental challenges and opportunities

Craven, C. B., Wawryk, N. J. P., Jiang, P., Liu, Z., & Li, X. (2019) · Journal of Environmental Sciences · doi:10.1016/j.jes.2019.04.028 · Cited by 44 · see citing works

Drying of cannabis—state of the practices and future needs

Challa, S. K. R., Misra, N. N., & Martynenko, A. I. (2020) · Drying Technology · doi:10.1080/07373937.2020.1752230 · Cited by 45 · see citing works

Antiinflammatory Potential of Medicinal Plants: A Source for Therapeutic Secondary Metabolites

Bernstein, N., Akram, M., Daniyal, M., Koltai, H., Fridlender, M., & Gorelick, J. (2018) · Advances in agronomy · doi:10.1016/bs.agron.2018.02.003 · Cited by 44 · see citing works

Δ9-Tetrahydrocannabinol attenuates allogeneic host-versus-graft response and delays skin graft rejection through activation of cannabinoid receptor 1 and induction of myeloid-derived suppressor cells

Sido, J. M., Nagarkatti, P. S., & Nagarkatti, M. (2015) · Journal of Leukocyte Biology · doi:10.1189/jlb.3a0115-030rr · Cited by 43 · see citing works

Prevalence and correlates of “Vaping” as a route of cannabis administration in medical cannabis patients

Cranford, J. A., Bohnert, K. M., Perron, B. E., Bourque, C. A., & Ilgen, M. A. (2016) · Drug and Alcohol Dependence · doi:10.1016/j.drugalcdep.2016.10.008 · Cited by 43 · see citing works

Utilization patterns of 2015 updated Beers criteria high risk medications in a nationwide Medicare population

Forrester, C. B., Lin, A., Tso, L., Thach, T., Pohler, J., & Lew, H. C. (2016) · Research in Social and Administrative Pharmacy · doi:10.1016/j.sapharm.2016.05.009

Pharmacy performance measures submitted by URAC accredited specialty pharmacies in 2015

Ansari, R. (2016) · Research in Social and Administrative Pharmacy · doi:10.1016/j.sapharm.2016.05.005

The Provision of Pharmaceutical Care Services in Oncology Settings in Egypt

Aref, H. A. T., Ebeid, A. I., & Abdelmoneim, N. (2016) · Research in Social and Administrative Pharmacy · doi:10.1016/j.sapharm.2016.05.036

Impact of the hydrocodone schedule change on opioid prescription patterns in South Dakota

Mort, J. R., & Kuschel, L. M. (2016) · Research in Social and Administrative Pharmacy · doi:10.1016/j.sapharm.2016.05.017 · Cited by 7 · see citing works

Effect of pharmacist-provided decision support on statin prescribing in the primary care setting

Simon, J., Patel, R. A., & Long, J. (2016) · Research in Social and Administrative Pharmacy · doi:10.1016/j.sapharm.2016.05.012