Piperine: A review of its biological effects

Prevalence of Obesity Among Adults and Youth: United States, 2015-2016.

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Influence of piperine on the pharmacokinetics of curcumin in animals and human volunteers

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Immunomodulatory and antitumor activity of Piper longum Linn. and piperine

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Targeting breast stem cells with the cancer preventive compounds curcumin and piperine

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Antioxidant and anti-inflammatory effects of curcuminoid-piperine combination in subjects with metabolic syndrome: A randomized controlled trial and an updated meta-analysis

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Biological role of Piper nigrum L. (Black pepper): A review

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Piper nigrum and Piperine: An Update

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Intranasal Piperine-Loaded Chitosan Nanoparticles as Brain-Targeted Therapy in Alzheimer's Disease: Optimization, Biological Efficacy, and Potential Toxicity

Elnaggar, Y. S. R., Etman, S. M., Abdelmonsif, D. A., & Abdallah, O. Y. (2015) · Journal of Pharmaceutical Sciences · doi:10.1002/jps.24557 · Cited by 327

Acylhydrazone Derivatives: An Overview of Biological Activities

Luong, L. Q., Linh, P. T. K., Phuong, C. T. H., Ngoc, N. T., & Vu, T. K. (2025) · Current Bioactive Compounds · doi:10.2174/0115734072409057250813101844 · Cited by 1

Contact Toxicity, Electrophysiology, Anti-Mating, and Repellent Effects of Piper guineense Against Spodoptera frugiperda (Lepidoptera: Noctuidae)

Akinbuluma, M. D., Deere, J. A., Roessingh, P., & Groot, A. T. (2025) · Insects · doi:10.3390/insects16090908 · Cited by 1

Natural histone deacetylase inhibitions from legumes: Exploring epigenetics modulation through systems biology

Rizwan, A., Aqeel, A., Choudhary, F., Nizam, A., Khan, A., & Farooqi, H. (2025) · Nutrition · doi:10.1016/j.nut.2025.112955 · Cited by 1

Assessment of the effect of Lasianthera africana on Interleukin-6, tumor necrosis factor-alpha and other inflammatory markers in inflamed wistar rats

Anorue, E. C., Ozougwu, V. E. O., Orhonigbe, I. O., Ezeachogu, M. O., & Joshua, P. E. (2025) · Inflammopharmacology · doi:10.1007/s10787-025-02036-x · Cited by 1

Piperine Inhibits the Immune Checkpoint CD47 to Enhance Immunity Against Pancreatic Cancer

He, X., Lu, Y., Zhang, H., Lin, B., Lu, H., Yu, Z., Li, Y., Xi, Q., & Zhang, R. (2025) · Phytotherapy Research · doi:10.1002/ptr.70110 · Cited by 1

Nanotechnology in Food Industry: Current Status and Future Trends

Mohapatra, M. (2025) · Smart nanomaterials technology · doi:10.1007/978-981-95-0136-6_1 · Cited by 1

Piperine Targets the FANCL/UBE2T Complex to Inhibit the FA Pathway and Sensitize Bladder Cancer to Cisplatin

Li, C., Lv, G., Yue, Y., Ma, G., & Lu, B. (2025) · Dose-Response · doi:10.1177/15593258251404060 · Cited by 1

A synergistic investigation on halogen driven piperidine derivatives as caix inhibitors: From crystal packing to docking analysis

Tharani, R., Priya, R. V., Al-Shemaimari, K. I., Almansour, A. I., Kumar, R. S., & Rajput, K. (2025) · Journal of Molecular Structure · doi:10.1016/j.molstruc.2025.145065 · Cited by 1

Unveiling the Multifaceted Potential of Piper nigrum : A Comprehensive Review of Its Chemical Components, Health Benefits, Safety Assessment and Industrial Application

Ding, L., Fei, T., Xiao, J., & Wang, L. (2026) · Journal of Agricultural and Food Chemistry · doi:10.1021/acs.jafc.5c15160 · Cited by 1

The difference in light intensities during culture affects the production of health-beneficial metabolites in a diatom used in producing aquaculture feed

Takebe, H., Sakurai, A., & Imamura, S. (2026) · Scientific Reports · doi:10.1038/s41598-026-37956-3 · Cited by 1

Chemical basis for the antioxidant activity of Piper nigrum: integrative profiling of volatile components from multi-origin black and white pepper

Lin, J., Zheng, X., Zhong, X., Lü, X., Zhang, W., & Jiang, Y. (2026) · Food Chemistry · doi:10.1016/j.foodchem.2026.148233 · Cited by 1

Purification of a Plant-Based Bioactive Compound Aided by Geometric Calculation of a Quasi-Ternary Phase Diagram: The Case of Piperine

Chang, C.-L., Pratama, D. E., & Lee, T. (2026) · Organic Process Research & Development · doi:10.1021/acs.oprd.5c00392 · Cited by 1

Piperine inhibits biofilm formation in co-cultures of Pseudomonas aeruginosa and Staphylococcus aureus

Das, S., Roy, R., Malik, M., Paul, P., Chakraborty, P., Chatterjee, S., Maiti, D., & Tribedi, P. (2026) · Biofouling · doi:10.1080/08927014.2026.2630947 · Cited by 1

Piperine as a modulator of cancer hallmarks: mechanistic insights and therapeutic potential

Talib, W. H., Kadhim, M. J., Junaidi, H. S. A., Braiek, A. B., Mohanna, W. M., Alfaleet, Y. A., Hadi, R. W., Law, D. S. N., Prashant, A., Takács, K., et al. (2026) · Frontiers in Oncology · doi:10.3389/fonc.2026.1810344 · Cited by 1

Novel Piperine derivatives containing substituted Benzamide fragments: Design, synthesis, anti-breast cancer activity, and mechanistic study on the PI3K/AKT/mTOR pathway

Song, M., Zhou, Y., Wang, S., Wang, M., Li, K., Zhang, B., Asan, K., Lin, H., Wang, J., Hao, H., et al. (2026) · Bioorganic & Medicinal Chemistry · doi:10.1016/j.bmc.2026.118668 · Cited by 1

A to Z of Health: An Evidence-Based Narrative Review of Multivitamin-Multimineral and Nutraceutical Supplementation

Nawathe, V. A., Verma, S., Pal, A., Pawar, D., & Sharma, A. (2026) · Cureus · doi:10.7759/cureus.108032 · Cited by 1

Alternative and Complementary Therapies: A Review Exploring the Role of Yoga and Ayurveda-based Herbal Medicines in Alleviating Hypothyroidism and Its Neuropsychiatric Manifestations

Jaglan, G., Balkrishna, A., & Varshney, A. (2026) · Annals of Neurosciences · doi:10.1177/09727531261440119 · Cited by 1

Piperine inhibits NLRP3 inflammasome activation and alleviates inflammatory disease

Guo, R., Niu, Z., Chen, F., Zheng, L., Li, J., Qi, L., Wu, G., Wang, X., Xu, F., Cho, J. Y., et al. (2026) · Phytomedicine · doi:10.1016/j.phymed.2026.158448 · Cited by 1

Liposomal drug delivery for lung cancer therapy: progress, challenges, and future perspectives

Vatankhah, A., Moghaddam, S. H., Rahmanian, M., Khosropanah, S., Oroojalian, F., Kesharwani, P., & Sahebkar, A. (2026) · Molecular Cancer · doi:10.1186/s12943-026-02728-0 · Cited by 1

Evaluation of Diffusivity Values and Extraction Speed Constants on Black Pepper Piperine Isolation

Mustikaningrum, M., Arista, D., Nyamiati, R. D., & Nanda, D. E. (2023) · Eksergi · doi:10.31315/e.v20i2.8996 · Cited by 1

Functional foods as immunomodulators: Tackling the SARS-CoV-2 related cytokine storm–A review

Kaur, H., & Singh, M. (2023) · Food Chemistry Advances · doi:10.1016/j.focha.2023.100407 · Cited by 1

Microbial Transformation of Curcumin and Synergistic Investigation of Its Derivatives with Piperine

Yetim, S. K., & Batur, Ö. Ö. (2024) · ChemistrySelect · doi:10.1002/slct.202304193 · Cited by 1

Molecular Evidence of the Bio-activities of Traditional Home Medicine Ingredients

Hora, J., Shetty, S., & Kabekkodu, S. P. (2024) · Current Topics in Medicinal Chemistry · doi:10.2174/0115680266302556240620054134 · Cited by 1

Biochemical studies in Woody Pepper (Piper pendulispicum C.DC.): A spice with edible stem from Andaman Islands, India

Waman, A. A., Bohra, P., & Devi, R. (2024) · Annals of Phytomedicine An International Journal · doi:10.54085/ap.2024.13.1.122 · Cited by 1

Investigation of the Anti-Diabetic Potential of Coccinia barteri (Hook.F.) Leaf Using in Vitro and in Silico Molecular Docking Approaches

Onugwu, S. O., Obi, P. E., Okoh, G. M., Onugwu, A. L., Madubugwu, R. C., Osita, T., Nnamani, O. H., Odoh, U. E., & Ezugwu, C. O. (2024) · Natural Product Communications · doi:10.1177/1934578x241271633 · Cited by 1

Cosmeceutical applications of alkaloids

Alom, S., Ali, F., Gohain, A., Das, A. K., & Kakoti, B. B. (2024) · Elsevier eBooks · doi:10.1016/b978-0-443-19148-0.00004-8 · Cited by 1

Piper nigrum and Piperine: Phytochemistry, Traditional Uses, Preclinical Studies, and Clinical Trials

Mollazadeh-Aval, A., Boghrati, Z., Rahman, A., Akaberi, M., & Emami, S. A. (2024) · Sustainable landscape planning and natural resources management · doi:10.1007/978-3-031-64601-0_6 · Cited by 1

Master Molecules of Spices

Ravindran, P. N. (2023) · Springer eBooks · doi:10.1007/978-981-19-3728-6_22 · Cited by 1

Piperonal protects neuron-like and retinalpigment epithelial (RPE) cells from oxidative stress and apoptosis through inhibition of α-synuclein aggregation

Wang, M., Yang, T., Chen, W., Bai, J., & Yang, P. (2024) · Arabian Journal of Chemistry · doi:10.1016/j.arabjc.2024.105982 · Cited by 1

Effects of Red, Green and Black Pepper on Intestinal Motility and Post-Prandial Bicarbonate Concentration in Guinea Pigs

Charles, C., Obia, O., Emmanuel, F. D., Ogba, A., & Ojeka, S. O. (2024) · EAS Journal of Nutrition and Food Sciences · doi:10.36349/easjnfs.2024.v06i04.004 · Cited by 1

Herbal Medicine Approach and their Effectiveness in the Management of Autism Spectrum Disorders

Alharbi, S. A. (2024) · Research Journal of Pharmacy and Technology · doi:10.52711/0974-360x.2024.00541 · Cited by 1

Harnessing Nature’s Bounty: Phytoinsecticides for a Healthier and Sustainable World

Thirunavukkarasu, S., Dhanapriya, P., & Iqbal, N. (2024) · IntechOpen eBooks · doi:10.5772/intechopen.1004815 · Cited by 1

Development of a New Salt of Piperine with Toluene Sulfonic Acid and Its Anti-Inflammation Effect In Vivo

Nugrahani, I., Sartinah, A., Uekusa, H., Abekura, Y., Ibrahim, S., & Anggadiredja, K. (2024) · Molecules · doi:10.3390/molecules29235631 · Cited by 1

Folk Medicine as a Source of Therapeutically Important Drugs: Evidence from Ethnobotanical Investigations

Raj, M. S. A., Kalaskar, M. G., Gurav, S. S., & Ayyanar, M. (2025) · Wiley eBooks · doi:10.1002/9781394203680.ch03 · Cited by 1

Metabolomic and proteomic analyses of renal function after liver transplantation

Wang, X., Grobe, N., Franchin, B., Levitsky, J., Cravedi, P., & Kotanko, P. (2025) · Frontiers in Transplantation · doi:10.3389/frtra.2025.1572852 · Cited by 1

Naturally occurring mutations exist at the functionally important motifs of piperine synthase genes among Piper species

Babu, D., Srinivasan, A., Soni, K. B., Alex, S., Soniya, E. V., & Anith, K. N. (2025) · Genetic Resources and Crop Evolution · doi:10.1007/s10722-025-02612-8 · Cited by 1

Spices and Gastrointestinal Health Benefits: A State-of-the-Art

Raoul, P. C., Chiara, C., Elisa, G., Mirella, N., Ginevra, P., Cintoni, M., Rinninella, E., Capristo, E., & Mele, M. C. (2023) · Nutrimentum et Curae · doi:10.57625/nec.2023.32 · Cited by 1

Targeting the mTOR Pathway with Natural Products: A Potential Therapeutic Approach for Autism Spectrum Disorders

Noori, T., Hosseini, S. Z., Alavi, S. D., Sureda, A., & Shirooie, S. (2026) · Current Neuropharmacology · doi:10.2174/011570159x388575251126041202 · Cited by 1

How to Deal with Ion Suppression – the Foe of HPLC-MS/MS

Seger (2009) · Scientia Pharmaceutica · doi:10.3797/scipharm.oephg.21.sl-03

Piperine Attenuates the Inflammatory Response, Oxidative Stress and Pyroptosis to Facilitate Recovery After Spinal Cord Injury via Autophagy EnhancementPreprint

Zhang, H., Wu, C., Huang, J.-F., Chen, Y., & Ni, W. (2021) · Research Square · doi:10.21203/rs.3.rs-257883/v1

An Overview of Bioactive Alkaloid, Semi-Synthetic Analogs, Mechanism of Action and Structure-Activity Relationship of Piperine as Antioxidant

Joshi, S., Salahuddin, S., Kumar, R., & Sharma, D. (2021) · Asian Journal of Chemistry · doi:10.14233/ajchem.2021.23430

Descripción de los Factores de Rentabilidad de los Medios Universitarios

Paz, A., Romero, S., & Díaz, B. (2005) · Revista Arbitrada Formación Gerencial

Is Co-Administration Curcumin and Piperine a Benefit in Preventing Metabolic Syndrome?

Finelli, C. (2022) · Archives of Medical Case Reports and Case Study · doi:10.31579/2692-9392/099

New Formulation Effective against SARS CoV-2 and H1N1

Duran, N. (2022) · International Conference on Advanced Materials and Systems (ICAMS) · doi:10.24264/icams-2022.iii.11

Inhibition of the JAK2/STAT3 Signaling Pathway by Piperine Confers Neuroprotection in Rats with Ischemic StrokePreprint

Zou, Y., Zhang, T., Zhao, W., Shi, X., Feng, Y., & Chen, J. (2023) · Research Square · doi:10.21203/rs.3.rs-2829651/v1

Hand-in-glove Effect of Piperine in Anti-cancer Formulations

Kumar, J., Kriplani, P., & Guarve, K. (2023) · Current Functional Foods · doi:10.2174/2666862901666230727104158

Phytochemicals for neurodegeneration and neuroinflammation: medicine of the future or a mirage?

Mythri, R. B. (2023) · Elsevier eBooks · doi:10.1016/b978-0-443-19084-1.00006-5

Tocolytic Effect of White Pepper (Piper nigrum Linn.) on Isolated Rat Uterine Contraction in vitro

Sawangjaroen, K., & Sarnkhaeveerakul, P. (2023) · Trends in Sciences · doi:10.48048/tis.2023.6149

Qualitative and quantitative analysis of siddha herbal Formulation Kabasura kudineer in various concentrations

Punitha, D., Elansekaran, S., Sudha Revathy, S., Ramamurthy, M., Srinivasan, V. J., Gayatri, R., & Christian, G. J. (2024) · International Journal of Ayurvedic Medicine · doi:10.47552/ijam.v14i4.4107

Piperine has anti-tumor effects in breast cancer by inducing mitochondrial apoptosis pathway

Naseh, V., Rezaeidian, J., Entezari, M., Ziyadi, H., & Hashemi, M. (2023) · Journal de Téhéran · doi:10.61186/jhgg.7.1.5

Oral Administration of Piperine Ameliorates Experimental Autoimmune Uveitis

Ghavami, A., Froushani, S. M. A., & Tehrani, A. (2024) · Inflammation · doi:10.1007/s10753-024-02131-1

The effect of bioenhancers on ampicillin-sulbactam as a treatment against A. baumannii

Balaji, A. (2024) · Journal of Emerging Investigators · doi:10.59720/23-215

Otoimmün Hastalıkların Tedavisi İçin Yeni Bir Umut: Piperin

Işkın, A. E., Şimşek, A., & Budak, F. (2024) · Uludağ Üniversitesi Tıp Fakültesi Dergisi · doi:10.32708/uutfd.1460014

Black‐and‐white pepper: unravelling Cruella De Vil 's medical diagnoses

D’Acunto, L., & Brigo, F. (2024) · Internal Medicine Journal · doi:10.1111/imj.16551

ACTIVIDAD ANTIOXIDANTE DE LOS ÉSTERES DEL ÁCIDO PIPÉRICO SINTETIZADOS A PARTIR DEL PIPER NIGRUM

Martel, C. R., Ramirez, C. T., & Cabanillas, B. J. (2024) · Revista de la Sociedad Química del Perú · doi:10.37761/rsqp.v90i01.455

A comprehensive review of spices: Use of prevalent preservative techniques and bio-preservatives for enhancing shelf life of spices

Zahra, N. (2024) · Nutrition and Food Processing · doi:10.31579/2637-8914/277

Survival of transport-stressed black pepper stem cuttings after glucose, sucrose, fructose, and IBA treatments

Zakry, F. A. A., Idris, N. N. I., Sazili, M. I. N. H. M., Kundat, F. R., Saupi, N., & Bokhari, S. (2025) · The Journal of Phytology · doi:10.25081/jp.2025.v17.9091

Bioprospecting ethnopharmacological plants for endophytic fungal drug discovery

Buddha, S., Gambhir, L., Kumar, Y., Sharma, G., Sharma, A., & Kapoor, N. (2025) · Elsevier eBooks · doi:10.1016/b978-0-443-31484-1.00001-3

A Combined Turmeric and Allspice Supplement Improves Metabolic Health in Obese Rats by Reducing Carbohydrate and Lipid Absorption

Barragán‐Zuñiga, L. J., Herrera, M. D., Simental‐Mendía, L. E., Zamilpa, A., Morales-Ferra, D. L., Martínez‐Aguilar, G., Salas-Pacheco, J. M., & Gamboa‐Gómez, C. I. (2025) · Journal of Medicinal Food · doi:10.1089/jmf.2024.0024

A Novel Piperine Derivative, NOHJ, Exerts Antibreast Cancer Effects by Inhibiting MDM2

Liu, X., He, J., Cheng, W., Wang, X., Zhang, M., Wang, S., Chen, L., Zhang, S., Zhou, L., Zhou, L., et al. (2025) · Russian Journal of Bioorganic Chemistry · doi:10.1134/s1068162024605718

Investigating Anti-skin Aging Activity of Piperine-loaded Ethosomal Formulation in UV-B Induced Photoaging in Mice Model

Dwivedi, D., Srivastava, N., Mishra, N., Singh, S. P., & Srivastava, A. (2025) · Journal of Natural Remedies · doi:10.18311/jnr/2025/48209

Therapeutic Potential of Bioactive Compounds from Traditional Chinese Medicine in Modulating Macrophage Cholesterol Metabolism for Atherosclerosis Treatment.

Yan, L., Guo, J., Huang, D., Zhang, F., Du, Z., Hou, X., Deng, J., Xie, Y., & Hao, E. (2025) · PubMed Central · doi:10.3390/ph18081113

Bioactives and Lipase Inhibitors from Underutilized Part of Piper longum: A Sustainable Source for Pseudoalkaloids and Alkamides

Guar, P., & Shanker, K. (2025) · Springer eBooks · doi:10.1007/978-3-642-36202-6_259-1

Therapeutic spectrum of Piperine in ischemic stroke: a literature review

Mallahzadeh, A., Owjfard, M., Fereydoonnezhad, T., & Karimi, F. (2025) · Molecular Biology Reports · doi:10.1007/s11033-025-10972-8

Interaction and solubility studies of curcumin in the presence of bioenhancing agents

de Andrade, Â. G. L. L., Cardoso, R. F., de Bona, J., Lacerda, L. H. D. S., de Freitas, C. F., & Parize, A. L. (2025) · Journal of Molecular Liquids · doi:10.1016/j.molliq.2025.128521

Spices to Combat Sepsis: Curcumin and Piperine Combination Increases Survival and Modulates Immune Response in a Murine Two-Hit Trauma Model

Schwenk, C., Muehlhaupt, N., Heimann, L., Friesen, A., Wan, L., Biberthaler, P., & Hanschen, M. (2025) · Shock · doi:10.1097/shk.0000000000002691

Piperine-loaded biogenic stabilized Selenium(0) nanoconjugates for synergistic antimicrobial and neuroprotective activities on peroxide-induced Parkinson-type SH-SY5Y cell

Nikalje, S. M., Sawant, V. J., Supale, A. R., Nipane, S. V., & Sawant, V. (2025) · Chemical Papers · doi:10.1007/s11696-025-04421-w

Chemo profiling and In-vitro Antioxidant, Anti-inflammatory Activities of Vilwadi Tablet-An Important Ayurvedic Formulation

Namboodiri, V. K., Sayanamol, P. V., Cherian, T., & Nampoothiri, S. V. (2025) · International Research Journal on Advanced Engineering and Management (IRJAEM) · doi:10.47392/irjaem.2025.0487

Rare and unconventional spices and herbs

Ali, A. A., El-Megeid, A. A. A., Dong, H., Sarbini, S. R., & Khalil, N. A. (2025) · Elsevier eBooks · doi:10.1016/b978-0-443-32920-3.00018-5

Globalization of Plant‐derived Molecules Against Progression and Metastasis of Cancer in the Last Few Decades

Kavita, K., Kumar, P., Singh, S., & Garg, N. (2025) · Wiley eBooks · doi:10.1002/9781394300594.ch09

Piperine and its derivatives as a therapeutic alternative against leishmaniasis: A comprehensive review

Brunetto, F., Costa, G., Oehler, V. S., Saroba, L. J., Seixas, R. P., BORDINIÃO, V. F., & Tomiotto‐Pellissier, F. (2025) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2025.178413

Antihyperlipidemic effects of plant-derived secondary metabolites

Rehman, K., & Akash, M. S. H. (2025) · Elsevier eBooks · doi:10.1016/b978-0-443-44135-6.00001-2

Unlocking the Therapeutic Potential of Piperine - From Ethnopharmacology to Nanodelivery Strategies

Wadhwa, K., Sagwal, J., Panwar, R., Koli, D., Pahwa, R., Goyal, R., Negi, P., & Verma, R. (2025) · Current Nanomedicine · doi:10.2174/0124681873431538251104034810

Prostogrit mitigates testosterone/estradiol induced prostatic enlargement/remodeling in rat model of benign prostatic hyperplasia and fine-tunes prostatic expression of Adra1a and Il6 genes

Balkrishna, A., Sinha, S., Pamidiboina, V., Tomer, M., Singh, R., Dev, R., & Varshney, A. (2025) · Frontiers in Endocrinology · doi:10.3389/fendo.2025.1663917

Additional file 2 of Piperine, a black pepper compound, induces autophagy and cellular senescence mediated by NF-κB and IL-6 in acute leukemia

Charoensedtasin, K., Kheansaard, W., Roytrakul, S., & Tanyong, D. I. (2024) · Figshare · doi:10.6084/m9.figshare.27129335

Additional file 1 of Integrated metabolomic and transcriptomic analysis reveals the regulatory mechanisms of flavonoid and alkaloid biosynthesis in the new and old leaves of Murraya tetramera Huang

Zhou, T., Xing, Q., Bu, J., Han, W., & Shen, Z. (2024) · Figshare · doi:10.6084/m9.figshare.25980545

Additional file 1 of Piperine, a black pepper compound, induces autophagy and cellular senescence mediated by NF-κB and IL-6 in acute leukemia

Charoensedtasin, K., Kheansaard, W., Roytrakul, S., & Tanyong, D. I. (2024) · Figshare · doi:10.6084/m9.figshare.27129332

Additional file 3 of Piperine, a black pepper compound, induces autophagy and cellular senescence mediated by NF-κB and IL-6 in acute leukemia

Charoensedtasin, K., Kheansaard, W., Roytrakul, S., & Tanyong, D. I. (2024) · Figshare · doi:10.6084/m9.figshare.27129338

Comunidades fúngicas na filosfera de espécies lenhosas do Cerrado : efeitos da adição de nutrientes ao solo

Costa, A. M. (2024) · LA Referencia (Red Federada de Repositorios Institucionales de Publicaciones Científicas)

Secondary metabolites produced by plants with antimicrobial properties

Santamaría Cuevas, M. (2023) · Buleria (Universidad de León)

Fruit chemical traits shape bat nutritional ecology: from basic science to applications

Gelambi Desiato, M. (2024) · VTechWorks (Virginia Tech)

Clinical trials unveiling the potential of phytochemicals across different diseases

Kundu, A., Rooj, P., Joardar, N., Sinha, A. K., & Sen, A. (2025) · Elsevier eBooks · doi:10.1016/b978-0-443-26494-8.00019-7

Fruits, Vegetables, Plant-based Diets, and Breast Cancer

Riseberg, E. E. (2025) · Digital Access to Scholarship at Harvard (DASH) (Harvard University)

A novel compound mixture mitigates hyperglycemia, insulin resistance, dyslipidemia, and oxidative stress in streptozotocin induced diabetic rats: A therapeutic drug lead for metabolic syndrome

Sampath, T. I., Jayasinghe, S., Attanayake, A. P., & Karunaratne, V. (2026) · Fitoterapia · doi:10.1016/j.fitote.2026.107091

A comprehensive review of anti‐colorectal cancer alkaloids from traditional Chinese medicine: Sources, chemical structures, mechanisms and therapeutic applications

Cong, K., Xu, M., Wu, Z., Dong, J., & Guo, M. (2026) · British Journal of Pharmacology · doi:10.1111/bph.70343

Efficacy and Safety of Black Pepper Supplementation in Adults with Borderline Hypercholesterolemia: A Randomized, Placebo-Controlled Trial

Woottisin, S., Imphat, C., Munjit, S., & Woottisin, N. (2026) · Tropical Journal of Natural Product Research · doi:10.26538/tjnpr/v10i1.54

Pathophysiological Effects of Titanium Dioxide Nanoparticles and the Protective Role of Piperine and a Piperine-TiO₂NP Combination in Rats.

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From Traditional Food to Nutraceuticals: LC-HRMS Identifies Leaves and Roots Antidiabetic Metabolites of Amaranthus spinosus L. and Amaranthus viridis L. from Buru Island (Wallacea Areas)

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Histopathological and Hematological Effects of Nano-Piperine in Ameliorating Dexamethasone-Induced Immunosuppression in Male Rats

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Pharmacogostical and Pharmacological Evaluation of Solanum Nigrum for diabetes induced vascular dementia

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EFFECT OF PIPERINE ON MODULATING SKIN WOUND HEALING AND AS AN ANTIMICROBIAL AGENT IN VIVO: A SYSTEMATIC REVIEW OF PRECLINICAL STUDIES

Melo, H. D. C. E. S., Soares, T., Mendes, V. R., Melo, S. M., de Freitas, R. A. B., Júnior, J. R. D. S., Filho, A. L. M. M., & Martins, M. D. C. D. C. E. (2026) · RECIMA21 - Revista Científica Multidisciplinar · doi:10.47820/recima21.v7i4.7477

Discovery of anti-renal fibrosis quality markers from Piperis longi fructus: An integrated strategy of hollow fibre cell trapping method coupled with liquid chromatography-mass spectrometry and in vitro efficacy verification

Zhang, X., Li, Q., Wang, R., Xing, R.-R., Chen, X., Liu, J. H., & Hu, S. (2026) · Journal of Pharmaceutical and Biomedical Analysis · doi:10.1016/j.jpba.2026.117497

Rotational chamber cold plasma: A novel approach to enhance the nutritional and antioxidant value of golden milk

Yusufoğlu, B., Sanli, I., Özkan, G., Güneş, Z. S., Çapanoğlu, E., & Esatbeyoglu, T. (2026) · Applied Food Research · doi:10.1016/j.afres.2026.101972

Low‐Pressure Microwave Air Plasma Decontamination of Black Pepper ( Piper nigrum ): From Microbial Efficacy to Quality Preservation

Soulier, M., Kais, A., Maho, T., Guillot, P., & Muja, C. (2026) · Plasma Processes and Polymers · doi:10.1002/ppap.70165

Caractérisation des extraits actifs de sous-produits de vigne, amande et abricot

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Advancing management of mining-related lung diseases: Synergies between nutraceuticals and artificial intelligence

Singh, D., Ghosh, A., Pandey, B., & Pandey, J. K. (2026) · PharmaNutrition · doi:10.1016/j.phanu.2026.100494

The Anticancer Effect of Curcumin and Piperine Combination in Non-Small Cell Lung Cancer Cells

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Isolation and Identification of Bioactive Fatty Acid Amides From Piper longum Fruits

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The water-soluble alkaloid from Sophora moorcroftiana enhances Tregs populations and ameliorate ulcerative colitis in mice

Yang, Q., Yang, N., Zhang, Y., An, S., Si, X., Kong, W., Bao, T., Zhang, D., Sheng, L., Ma, X., et al. (2026) · International Immunopharmacology · doi:10.1016/j.intimp.2026.116653

Piperine-primed rat mesenchymal stem cells’ secretome promotes an anti-inflammatory phenotype in the J774.1 murine macrophage cell line

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A Review on Therapeutic Potential of Piper nigrum L. (Black Pepper): The King of Spices

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Therapeutic Role of Piper nigrum L (Black Pepper) and Pharmacological Activities

Saleem, A., Naureen, I., Naeem, M., Tasleem, G., Ahmed, H., & Farooq, U. (2022) · Scholars International Journal of Biochemistry · doi:10.36348/sijb.2022.v05i01.003 · Cited by 41

Therapeutic Potential of Piperine: A Review

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Therapeutic Potential of Piperine: A Comprehensive Review

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