Psychological resilience, affective mechanisms and symptom burden in a tertiary-care sample of patients with fibromyalgia
Open accessAbstract
Research demonstrates that patients with fibromyalgia who have higher positive and lower negative affect have lower symptom burden. Affect has been shown to be associated with resilience. This study examined the relationship between affect, resilience and fibromyalgia symptom burden in a clinical sample of patients with fibromyalgia. We hypothesized that (a) positive and negative affect would be associated with fibromyalgia symptom burden; (b) resilience would be associated with positive and negative affect; (c) resilience would be associated with fibromyalgia symptom burden; and (d) the connection between resilience and fibromyalgia symptom burden would be mediated by both positive and negative affect. A sample of 858 patients with fibromyalgia completed questionnaires. Mediation modelling revealed statistically significant direct effects of resilience on fibromyalgia symptom burden (β = -0.10, P < 0.001) and statistically significant indirect effects of resilience on fibromyalgia symptom burden through affect (β = -0.36, P < 0.001), suggesting that both resilience and affect influence fibromyalgia symptom burden. Our results suggest that improving affect through resiliency training could be studied as a modality for improving fibromyalgia symptom burden.
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Resilience is influenced by genetic, epigenetic, developmental, neurochemical, and psychosocial factors.
“and is influenced by genetic, epigenetic, developmental, neurochemical, and psychosocial factors (13, 14).”
From Digital resilience interventions for healthcare workers: a systematic review (2025) · cites this paper as [14]
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Digital resilience interventions for healthcare workers: a systematic review
Larsson, M., Ho, D. M., Kirschner, M., Seifritz, E., & Manoliu, A. (2025) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2025.1519670 · Cited by 14 · see citing works
- Authors
- McAllister, S. J., Vincent, A., Hassett, A. L., Whipple, M. O., Oh, T. H., Benzo, R. P., & Toussaint, L. L.
- Affiliations
- Mayo Clinic (US)
- University of Michigan (US)
- Luther College (US)
- Corresponding author
- Vincent, Ann
- Venue
- Stress and Health
- Publisher
- Wiley
- Published
- 2013-12-26
- Volume
- 31
- Issue
- 4
- Pages
- 299-305
- ISSN
- 1532-2998 (ISSN-L)
- 1532-3005
- PMC
- PMC4077991
- OpenAlex
- W1549133158
- Cited by
- 40
- References
- 47
- Citations by year
- 2026: 5 · 2025: 5 · 2024: 5 · 2023: 3 · 2022: 4 · 2021: 2 · 2020: 4 · 2019: 3 · 2018: 2 · 2017: 1 · 2016: 2 · 2015: 2 · 2014: 2
- FWCI
- 1.42
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Stress and Health (publishedVersion)
- PubMed (publishedVersion)
- Europe PMC (PubMed Central) (acceptedVersion)
- PubMed Central (acceptedVersion)
- Deep Blue (University of Michigan) (submittedVersion)
- Funders
- National Center for Research Resources (NCRR)
- National Institutes of Health (NIH) (RR024150)
- Topics
- Health Sciences › Medicine › Psychiatry and Mental health › Fibromyalgia and Chronic Fatigue Syndrome Research
- Social Sciences › Psychology › Clinical Psychology › Resilience and Mental Health
- Health Sciences › Medicine › Psychiatry and Mental health › Psychosomatic Disorders and Their Treatments
- Keywords
- fibromyalgia, psychological resilience, positive affect, negative affect, symptom burden, mediation, resilience training, chronic pain
- MeSH terms
- Adult, Affect, Aged, Fatigue, Female, Fibromyalgia, Humans, Male, Middle Aged, Pain Measurement, Psychiatric Status Rating Scales, Surveys and Questionnaires, Resilience, Psychological, Chronic Pain, Tertiary Health Care, Tertiary Healthcare
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