Extracts of Jasminum sambac flowers fermented by Lactobacillus rhamnosus inhibit H2O2‐ and UVB‐induced aging in human dermal fibroblasts
Abstract
Abstract Ultraviolet (UV) irradiation is a crucial factor that leads to skin photoaging and results in increased DNA damage, oxidative stress, and collagen degradation. Jasmine flowers have been utilized as a traditional medicine in Asia to treat various diseases, including dermatitis, diarrhea, and fever. Furthermore, the fermented broth of Lactobacillus rhamnosus has been reported to exert protective effects on the skin. In the present study, jasmine flower extract was fermented with L. rhamnosus. We investigated the antioxidant and collagen‐promoting effects on UVB/H2O2‐induced HS68 dermal fibroblast cell damage. The results indicated that treatment with the fermented flower extracts of Jasminum sambac (F‐FEJS) could enhance the viability of HS68 cells. Furthermore, the UVB/H2O2‐induced excessive production of reactive oxygen species, degradation of collagen, activation of MAPKs, including P38, ERK, and JNK, and premature senescence were remarkably attenuated by F‐FEJS in dermal fibroblast cells. The nuclear accumulation of p‐c‐jun, which is downstream of MAPK, and the inactivation of p‐smad2/3, which is one of the crucial transcription factors that enhance collagen synthesis, were reversed in response to F‐FEJS treatment in UVB/H2O2‐exposed cells. Notably, the expression of antioxidant genes, such as HO‐1, and the nuclear translocation of Nrf2 were further enhanced by F‐FEJS in UVB/H2O2‐treated cells. Interestingly, the F‐FEJS‐induced increase in ARE luciferase activity indicated the activation of Nrf2/ARE signaling. In conclusion, our findings demonstrated that F‐FEJS can effectively ameliorate UVB/H2O2‐induced dermal cell aging and may be considered a promising ingredient in skin aging therapy.
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Fermented Jasminum sambac flowers with Lactobacillus rhamnosus have antioxidant, anti-aging, and anti-photoaging induced by UVB radiation properties.
“Jasminum sambac flowers Lactobacillus rhamnosus Antioxidant, anti-aging, anti-photoaging induced by UVB radiation, [160]”
From Use of Waste from the Food Industry and Applications of the Fermentation Process to Create Sustainable Cosmetic Products: A Review (2024) · cites this paper as [160]
Cites
Nrf2:INrf2 (Keap1) signaling in oxidative stress
Kaspar, J. W., Niture, S. K., & Jaiswal, A. K. (2009) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2009.07.035 · Cited by 1,646 · see citing works
Pathophysiology of Premature Skin Aging Induced by Ultraviolet Light
Fisher, G. J., Wang, Z., Datta, S. C., Varani, J., Kang, S., & Voorhees, J. J. (1997) · New England Journal of Medicine · doi:10.1056/nejm199711133372003 · Cited by 1,501 · see citing works
Probiotics and their fermented food products are beneficial for health
Parvez, S., Malik, K. A., Ah Kang, S., & Kim, H.-Y. (2006) · Journal of Applied Microbiology · doi:10.1111/j.1365-2672.2006.02963.x · Cited by 1,435 · see citing works
Daynes, R. A., Araneo, B. A., Ershler, W. B., Maloney, C., Li, G. Z., & Ryu, S. Y. (1993) · The Journal of Immunology · doi:10.4049/jimmunol.150.12.5219 · Cited by 1,264 · see citing works
Mechanistic Studies of the Nrf2-Keap1 Signaling Pathway
Zhang, D. D. (2006) · Drug Metabolism Reviews · doi:10.1080/03602530600971974 · Cited by 1,091 · see citing works
UV-light-induced signal cascades and skin aging
Rittié, L. (2002) · Ageing Research Reviews · doi:10.1016/s1568-1637(02)00024-7 · Cited by 987 · see citing works
Kobayashi, A., Kang, M.-I., Watai, Y., Tong, K. I., Shibata, T., Uchida, K., & Yamamoto, M. P. (2005) · Molecular and Cellular Biology · doi:10.1128/mcb.26.1.221-229.2006 · Cited by 933 · see citing works
Matrix-Degrading Metalloproteinases in Photoaging
Quan, T., Qin, Z., Xia, W., Shao, Y., Voorhees, J. J., & Fisher, G. J. (2009) · Journal of Investigative Dermatology Symposium Proceedings · doi:10.1038/jidsymp.2009.8 · Cited by 740 · see citing works
A protective role of nuclear factor-erythroid 2-related factor-2 (Nrf2) in inflammatory disorders
Kim, J., Cha, Y., & Surh, Y. (2009) · Mutation research. Fundamental and molecular mechanisms of mutagenesis · doi:10.1016/j.mrfmmm.2009.09.007 · Cited by 686 · see citing works
Ultraviolet light induced generation of reactive oxygen species
de Jager, T. L., Cockrell, A. E., & Du Plessis, S. S. (2017) · Advances in Experimental Medicine and Biology · doi:10.1007/978-3-319-56017-5_2 · Cited by 523 · see citing works
Quan, T., & Fisher, G. J. (2015) · Gerontology · doi:10.1159/000371708 · Cited by 464 · see citing works
Quan, T., He, T., Kang, S., Voorhees, J. J., & Fisher, G. J. (2004) · American Journal Of Pathology · doi:10.1016/s0002-9440(10)63337-8 · Cited by 386 · see citing works
Ultraviolet Radiation, Aging and the Skin: Prevention of Damage by Topical cAMP Manipulation
Amaro-Ortiz, A., Yan, B., & D'Orazio, J. (2014) · Molecules · doi:10.3390/molecules19056202 · Cited by 360 · see citing works
Chung, J. H. (2003) · Photodermatology Photoimmunology & Photomedicine · doi:10.1034/j.1600-0781.2003.00027.x · Cited by 269 · see citing works
Probiotic Administration in Early Life, Atopy, and Asthma: A Meta-analysis of Clinical Trials
Elazab, N., Mendy, A., Gasana, J., Vieira, E. R., Quizon, A., & Forno, E. (2013) · PEDIATRICS · doi:10.1542/peds.2013-0246 · Cited by 269 · see citing works
UVA-mediated activation of signaling pathways involved in skin tumor promotion and progression
Bachelor, M. A., & Bowden, G. T. (2004) · Seminars in Cancer Biology · doi:10.1016/j.semcancer.2003.09.017 · Cited by 268 · see citing works
Antiproliferative Activity of Plant Extracts Used Against Cancer in Traditional Medicine
Talib, W. H. (2010) · Scientia Pharmaceutica · doi:10.3797/scipharm.0912-11 · Cited by 228 · see citing works
Imokawa, G., & Ishida, K. (2015) · International Journal of Molecular Sciences · doi:10.3390/ijms16047753 · Cited by 206 · see citing works
Understanding Premature Skin Aging
Uitto, J. (1997) · New England Journal of Medicine · doi:10.1056/nejm199711133372011 · Cited by 178 · see citing works
Debacq-Chainiaux, F., Leduc, C., Verbeke, A., & Toussaint, O. (2012) · Dermato-Endocrinology · doi:10.4161/derm.23652 · Cited by 171 · see citing works
Ultraviolet Irradiation Alters Transforming Growth Factor β/Smad Pathway in Human Skin In Vivo
Quan, T., He, T., Kang, S., Voorhees, J. J., & Fisher, G. J. (2002) · Journal of Investigative Dermatology · doi:10.1046/j.1523-1747.2002.01834.x · Cited by 169 · see citing works
Hirota, A., Kawachi, Y., Itoh, K., Nakamura, Y., Xu, X., Banno, T., Takahashi, T., Yamamoto, M. P., & Otsuka, F. (2005) · Journal of Investigative Dermatology · doi:10.1111/j.0022-202x.2005.23670.x · Cited by 162 · see citing works
Tsai, C.-Y., Wang, C.-C., Lai, T.-Y., Tsu, H.-N., Wang, C., Liang, H.-Y., & Kuo, W. (2013) · International Journal of Cardiology · doi:10.1016/j.ijcard.2012.12.004 · Cited by 153 · see citing works
Hseu, Y., Lo, H.-W., Korivi, M., Tsai, Y.-C., Tang, M.-J., & Yang, H. (2015) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2015.05.026 · Cited by 134 · see citing works
Methods of Cellular Senescence Induction Using Oxidative Stress
Chen, J., Ozanne, S. E., & Hales, C. N. (2007) · Methods in molecular biology · doi:10.1007/978-1-59745-361-5_14 · Cited by 120 · see citing works
Bouilly-Gauthier, D., Jeannes, C., Maubert, Y., Duteil, L., Queille‐Roussel, C., Piccardi, N., Montastier, C., Manissier, P., Piérard, G. E., & Ortonne, J. ‐. (2010) · British Journal of Dermatology · doi:10.1111/j.1365-2133.2010.09888.x · Cited by 113 · see citing works
Molecular Mechanisms andIn VivoMouse Models of Skin Aging Associated with Dermal Matrix Alterations
Hwang, K., Yi, B.-R., & Choi, K. (2011) · Laboratory Animal Research · doi:10.5625/lar.2011.27.1.1 · Cited by 108 · see citing works
The Transforming Growth Factor‐Betas: A New Family of Immunoregulatory Molecules
Palladino, M. A., Morris, R. E., Starnes, H. F., & Levinson, A. D. (1990) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.1990.tb16110.x · Cited by 99 · see citing works
Connective tissue alterations in skin exposed to natural and therapeutic UV-radiation.
Oikarinen, A., Karvonen, J., Uitto, J., & Hannuksela, M. L. (1985) · PubMed · Cited by 96 · see citing works
Oyewole, A. O., Wilmot, M., Fowler, M., & Birch‐Machin, M. A. (2014) · The FASEB Journal · doi:10.1096/fj.13-237008 · Cited by 90 · see citing works
Wickens, K. L., Barthow, C. A., Mitchell, E. A., Kang, J., van Zyl, N., Purdie, G., Stanley, T., Fitzharris, P., Murphy, R., & Crane, J. (2018) · Pediatric Allergy and Immunology · doi:10.1111/pai.12982 · Cited by 89 · see citing works
Kim, H. M., Lee, D. E., Park, S. D., Kim, Y.-T., Kim, Y. J., Jeong, J. W., Jang, S. S., Ahn, Y.-T., Sim, J.-H., Huh, C.-S., et al. (2014) · Journal of Microbiology and Biotechnology · doi:10.4014/jmb.1406.06038 · Cited by 85 · see citing works
Weill, F. S., Eliana, M., Paz, M. L., Ferrari, A., Leoni, J., & Maglio, D. H. G. (2012) · British Journal Of Nutrition · doi:10.1017/s0007114512001225 · Cited by 82 · see citing works
Chung, K. W., Choi, Y. J., Park, M. H., Jang, E. J., Kim, D. H., Park, B. H., Yu, B. P., & Chung, H. Y. (2014) · The Journals of Gerontology Series A · doi:10.1093/gerona/glu137 · Cited by 74 · see citing works
Chiang, H., Chen, H., Chiu, H., Chen, C.-W., Wang, S.-M., & Wen, K. (2013) · Evidence-based Complementary and Alternative Medicine · doi:10.1155/2013/324864 · Cited by 66 · see citing works
Abdoul‐Latif, F. M., Mohamed, N. Z., Edou, P., Ali, A. A., O.Djama, S., Obame, L.-C., Bassolé, I., & Dicko, M. H. (2011) · Journal of Medicinal Plants Research · doi:10.5897/jmpr.9000171 · Cited by 65 · see citing works
Rautava, S., & Isolauri, E. (2002) · PubMed · Cited by 63 · see citing works
Yang, H.-L., Lin, M.-W., Korivi, M., Wu, J.-J., Liao, C.-H., Chang, C.-T., Liao, J.-W., & Hseu, Y. (2016) · Biochimica et Biophysica Acta · doi:10.1016/j.bbagrm.2015.11.001 · Cited by 62 · see citing works
Lactobacillus salivarius LA307 and Lactobacillus rhamnosus LA305 attenuate skin inflammation in mice
Holowacz, S., Blondeau, C., Guinobert, I., Guilbot, A., Hidalgo, S., & Bisson, J. (2018) · Beneficial Microbes · doi:10.3920/bm2017.0084 · Cited by 51 · see citing works
BORNSTEIN, P. K. (1996) · Matrix Biology · doi:10.1016/s0945-053x(96)90121-3 · Cited by 50 · see citing works
Anti-glycative effects of asiatic acid in human keratinocyte cells
Wang, Z.-H. (2014) · Biomedicine · doi:10.7603/s40681-014-0019-9 · Cited by 44 · see citing works
Galangin suppresses H2O2‐induced aging in human dermal fibroblasts
Wen, S., Chen, J., Weng, Y., Aneja, R., Chen, C., Huang, C., & Kuo, W. (2017) · Environmental Toxicology · doi:10.1002/tox.22455 · Cited by 41 · see citing works
Chiang, H., Chiu, H., Liao, S.-T., Chen, Y.-T., Chang, H., & Wen, K. (2013) · Evidence-based Complementary and Alternative Medicine · doi:10.1155/2013/696879 · Cited by 34 · see citing works
Wen, S., Chen, J., Chen, C., Huang, C., & Kuo, W. (2019) · Environmental Toxicology · doi:10.1002/tox.22847 · Cited by 25 · see citing works
Bhatt, P., & Patwardhan, J. (2015) · Pharmacognosy Magazine · doi:10.4103/0973-1296.168979 · Cited by 24 · see citing works
Bech-Thomsen, N., & Wulf, H. C. (1995) · Photochemistry and Photobiology · doi:10.1111/j.1751-1097.1995.tb08729.x · Cited by 23 · see citing works
Nrf2 Activation as a Protective Feedback to Limit Cell Death in High Glucose‐Exposed Cardiomyocytes
Tsai, C., Wen, S., Cheng, S., Wang, C., Yang, Y., Viswanadha, V. P., Huang, C., & Kuo, W. (2016) · Journal of Cellular Biochemistry · doi:10.1002/jcb.25785 · Cited by 19 · see citing works
Flagged first, then by citations
1 of the 48 references couldn’t be matched to a known paper.
Cited by
Sorted by citations
Galangin Reverses H2O2-Induced Dermal Fibroblast Senescence via SIRT1-PGC-1α/Nrf2 Signaling
Lee, J., Ng, S., Hsu, J.-Y., Liu, H., Chen, C., Huang, C., & Kuo, W. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23031387 · Cited by 118 · see citing works
Collagen study advances for photoaging skin
Liu, H., Dong, J., Du, R., Gao, Y., & Zhao, P. (2023) · Photodermatology Photoimmunology & Photomedicine · doi:10.1111/phpp.12931 · Cited by 86 · see citing works
Effect of ultraviolet radiation on the Nrf2 signaling pathway in skin cells
Ryšavá, A., Vostálová, J., & Svobodová, A. R. (2021) · International Journal of Radiation Biology · doi:10.1080/09553002.2021.1962566 · Cited by 65 · see citing works
Choi, S.-I., Han, H.-S., Kim, J., Park, G., Jang, Y. P., Shin, Y., Ahn, H.-S., Lee, S. H., & Lee, K. (2021) · Marine Drugs · doi:10.3390/md19120693 · Cited by 62 · see citing works
Balkrishna, A., Rohela, A., Kumar, A., Kumar, A., Arya, V., Thakur, P., Olekšák, P., Krejcar, O., Verma, R., Kumar, D., et al. (2021) · Plants · doi:10.3390/plants10061089 · Cited by 58 · see citing works
Applications of Probiotic Constituents in Cosmetics
Dou, J., Ning, F., Guo, F., Chen, Z., Jie, L., Wang, T., Guo, X., & Xu, Z. (2023) · Molecules · doi:10.3390/molecules28196765 · Cited by 50 · see citing works
Modeling of the Senescence-Associated Phenotype in Human Skin Fibroblasts
Gerasymchuk, M., Robinson, G. I., Kovalchuk, O., & Kovalchuk, I. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23137124 · Cited by 50 · see citing works
Krzyżostan, M., Wawrzyńczak, A., & Nowak, I. (2024) · Sustainability · doi:10.3390/su16072757 · Cited by 47 · see citing works
Zhao, C., Wu, S., & Wang, H. (2025) · International Journal of Molecular Sciences · doi:10.3390/ijms26052278 · Cited by 48 · see citing works
Chen, G., Mostafa, S., Lu, Z., Du, R., Cui, J., Wang, Y., Liao, Q., Lu, J., Mao, X., Chang, B., et al. (2022) · Genomics Proteomics & Bioinformatics · doi:10.1016/j.gpb.2022.12.005 · Cited by 44 · see citing works
Discovery of matrix metalloproteinase inhibitors as anti-skin photoaging agents
Li, F., Zhi, J., Zhao, R., Sun, Y., Wen, H., Cai, H., Chen, W., Jiang, X., & Bai, R. (2024) · European Journal of Medicinal Chemistry · doi:10.1016/j.ejmech.2024.116152 · Cited by 46 · see citing works
Ho, H.-H., Chen, C., Yi, T.-H., Huang, Y., Kuo, Y., Lin, J., Chen, J., Tsai, S., Chan, L., & Liang, C. (2022) · Journal of Cosmetic Dermatology · doi:10.1111/jocd.15228 · Cited by 36 · see citing works
Rai, S., Rai, G., & Kumar, A. (2022) · Microbiological Research · doi:10.1016/j.micres.2022.127044 · Cited by 32 · see citing works
Premna microphylla Turcz pectin protected UVB-induced skin aging in BALB/c-nu mice via Nrf2 pathway
Chen, Y., Liu, X., Lei, X., Lei, L., Zhao, J., Zeng, K., & Ming, J. (2022) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2022.06.076 · Cited by 23 · see citing works
Frontiers in Topical Photoprotection
Sullivan, M., Obezo, C. G., Lipsky, Z. W., Panchal, A., & Jensen, J. (2025) · Cosmetics · doi:10.3390/cosmetics12030096 · Cited by 20 · see citing works
Biotics as novel therapeutics in targeting signs of skin ageing via the gut-skin axis
Millman, J. F., Kondrashina, A. V., Walsh, C., Busca, K., Karawugodage, A., Park, J., Sirisena, S. D., Martin, F., Felice, V. D., & Lane, J. A. (2024) · Ageing Research Reviews · doi:10.1016/j.arr.2024.102518 · Cited by 18 · see citing works
Bioferments and Biosurfactants as New Products with Potential Use in the Cosmetic Industry
Klimek-Szczykutowicz, M., Błońska-Sikora, E. M., Kulik-Siarek, K., Zhussupova, A. I., & Wrzosek, M. (2024) · Applied Sciences · doi:10.3390/app14093902 · Cited by 15 · see citing works
Chinese Jasmine Tea: The Harmonious Intertwining of Tea and Jasmine Fragrance
Chen, H., Ying, J., An, H., Chen, Y., Huang, Y.-W., Jiang, Y., Wang, S., Bai, S., Shi, L., Huang, J., et al. (2025) · Comprehensive Reviews in Food Science and Food Safety · doi:10.1111/1541-4337.70210 · Cited by 13 · see citing works
Zhu, S., Qin, W., Liu, T., Liu, T., Ma, H., Hu, C., Yue, X., Yan, Y., Lv, Y., Wang, Z., et al. (2022) · Frontiers in Pharmacology · doi:10.3389/fphar.2022.976473 · Cited by 13 · see citing works
Dai, Z., Liang, S., Zhang, C., Sun, H., Zhou, L. L., Luo, F., & Chen, Z. (2024) · Journal of Food Composition and Analysis · doi:10.1016/j.jfca.2024.106592 · Cited by 11 · see citing works
Rescigno, A., Zucca, P., Peddio, S., Srikanth, S., Kaushik, N. P., Kumar, N. V. A., Leyva‐Gómez, G., Kręgiel, D., Abu‐Reidah, I. M., Sen, S., et al. (2025) · Food Frontiers · doi:10.1002/fft2.70024 · Cited by 11 · see citing works
Abera, W. A., Kassahun, S. K., Beyene, A. M., & Mohammed, S. A. (2024) · Biomass Conversion and Biorefinery · doi:10.1007/s13399-024-06372-w · Cited by 7 · see citing works
The jasmine ( Jasminum sambac ) genome and flower fragrancesPreprint
Chen, G., Mostafa, S., Lu, Z., Du, R., Cui, J., Wang, Y., Liao, Q., Lu, J., Mao, X., Chang, B., et al. (2020) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2020.12.17.420646 · Cited by 4 · see citing works
Zhu, F., Qu, L., Xu, R. P., Yuan, Y., Zhang, S., & Chen, Y. (2025) · Chemical and Biological Technologies in Agriculture · doi:10.1186/s40538-025-00856-1 · Cited by 3 · see citing works
Yuan, D., Yang, X., He, B., Han, Y., Wang, Y., Wu, D., & Pan, L. (2025) · Respiratory Research · doi:10.1186/s12931-025-03345-z · Cited by 2 · see citing works
Wang, H., Li, K., Li, D., Dong, A., Zhang, Q., Wang, C., Wang, J., Sun, J., & Zhao, C. (2025) · Journal of Ethnopharmacology · doi:10.1016/j.jep.2025.120478 · Cited by 2 · see citing works
Shoukat, S., Kamal, S., Bibi, I., Akhter, N., Rehman, S., & Khalid, M. (2023) · Springer eBooks · doi:10.1007/978-3-031-35403-8_35 · Cited by 2 · see citing works
The landscape of photoaging: From bench to bedside in a bibliometric analysis
Sun, P. H., Yan, W. T., Tian, R. F., Sun, Y., & Wu, Y. (2022) · Frontiers in Public Health · doi:10.3389/fpubh.2022.972766 · Cited by 2 · see citing works
Research Progress of Anti-Skin Aging Effect of Saponins
许, 敏. (2025) · Advances in Clinical Medicine · doi:10.12677/acm.2025.153785 · Cited by 1 · see citing works
Probiotics is riding high: effects of gut microbiota on skin health
Song, Z., Song, R., Lan, L., Cheng, K., & Zhang, X. (2025) · Food Science and Human Wellness · doi:10.26599/fshw.2025.9250467 · Cited by 1 · see citing works
White Biotechnology for Skincare
Paladugu, S., Sathwik, S. S., & Potu, M. (2026) · Wiley eBooks · doi:10.1002/9781394309955.ch7 · Cited by 1 · see citing works
Kamilijiang, M., Abudukelimu, N., Lu, X., Zhao, J., & Aisa, H. A. (2026) · Food Bioscience · doi:10.1016/j.fbio.2026.108834
Sunscreen and Vitamin D. Part II: Sunscreen, SPF and Impact on Vitamin D
Chukwudi, L. (2026) · Clinics in Dermatology · doi:10.1016/j.clindermatol.2026.04.007
Sunscreen and vitamin D: Part I
Nwabudike, L. C. (2026) · Clinics in Dermatology · doi:10.1016/j.clindermatol.2026.04.006
Zhen, Y., Li, Q., Hu, X., Liu, X., Shao, Z., Xie, H. Q., Zhao, B., & Xu, S. L. (2026) · International Journal of Molecular Sciences · doi:10.3390/ijms27083530
Shen, X., Zhu, F., Yang, X., Wu, M., Yang, N., Liu, D., Zhu, M., Zhang, W., & Xia, W. (2026) · Biocatalysis and Agricultural Biotechnology · doi:10.1016/j.bcab.2026.104146
BindingDB (2025) · UC San Diego · doi:10.7270/q2hd818f
- Authors
- Ho, C., Ng, S., Chuang, H., Wen, S., Kuo, C., Mahalakshmi, B., Huang, C., & Kuo, W.
- Affiliations
- China Medical University (TW)
- National Taipei University of Nursing and Health Science (TW)
- University of Taipei (TW)
- Duy Tan University (VN)
- Asia University (TW)
- Corresponding author
- Kuo, Wei‐Wen
- Venue
- Environmental Toxicology
- Publisher
- Wiley
- Published
- 2020-12-03
- Volume
- 36
- Issue
- 4
- Pages
- 607-619
- ISSN
- 1520-4081 (ISSN-L)
- 1522-7278
- OpenAlex
- W3108934495
- Cited by
- 37
- References
- 48
- Citations by year
- 2026: 6 · 2025: 10 · 2024: 6 · 2023: 3 · 2022: 8 · 2021: 3 · 2020: 1
- FWCI
- 2.74
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Environmental Toxicology (publishedVersion)
- PubMed (publishedVersion)
- Funders
- China Medical University (DMR‐108‐139)
- Topics
- Health Sciences › Medicine › Dermatology › Skin Protection and Aging
- Health Sciences › Medicine › Biochemistry › Phytochemicals and Antioxidant Activities
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Cell Biology › melanin and skin pigmentation
- Keywords
- Jasminum sambac, Lactobacillus rhamnosus, fermented plant extract, photoaging, dermal fibroblasts, collagen degradation, MAPK signaling, premature senescence, Nrf2/ARE signaling, antioxidant activity, heme oxygenase-1, c-Jun, Smad2/3
- MeSH terms
- Antioxidants, Cell Line, Fermentation, Fibroblasts, Humans, Hydrogen Peroxide, Plant Extracts, Ultraviolet Rays, Signal Transduction, Skin Aging, Cellular Senescence, Reactive Oxygen Species, Jasminum, Flowers, Lacticaseibacillus rhamnosus
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