CoChat
Sign Up
Cited by 111

The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.

The EH Network

Santolini, Elisa, Salcini, Anna Elisabetta, Kay, Brian K., Yamabhai, Montarop, Di Fiore, Pier Paolo·1999·Experimental Cell Research
DOI 10.1006/excr.1999.4694
Open this paper in CoChat — free account

Abstract

The EH domain is an evolutionary conserved protein-protein interaction domain present in a growing number of proteins from yeast to mammals. Even though the domain was discovered just 5 years ago, a great deal has been learned regarding its three-dimensional structure and binding specificities. Moreover, a number of cellular ligands of the domain have been identified and demonstrated to define a complex network of protein-protein interactions in the eukaryotic cell. Interestingly, many of the EH-containing and EH-binding proteins display characteristics of endocytic "accessory" proteins, suggesting that the principal function of the EH network is to regulate various steps in endocytosis. In addition, recent evidence suggests that the EH network might work as an "integrator" of signals controlling cellular pathways as diverse as endocytosis, nucleocytosolic export, and ultimately cell proliferation.

Overview

Integrity signals

Registry

Crossref · 10.1006/excr.1999.4694

Cites

2 of 2 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Verification

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Citations

Cites

Flagged first, then by citations

Research works printed but not linked: 193

  1. van der Geer, 1995, The PTB domain: A new protein module implicated in signal transduction, Trends Biochem. Sci., 20, 277, 10.1016/S0968-0004(00)89043-X · DOI
  2. Cohen, 1995, Modular binding domains in signal transduction proteins, Cell, 80, 237, 10.1016/0092-8674(95)90406-9 · DOI · Paper page
  3. Musacchio, 1994, Structure and function of the SH3 domain, Prog. Biophys. Mol. Biol., 61, 283, 10.1016/0079-6107(94)90003-5 · DOI
  4. Pawson, 1997, Signaling through scaffold, anchoring, and adaptor proteins, Science, 278, 2075, 10.1126/science.278.5346.2075 · DOI · Paper page
  5. Fazioli, 1993, eps15, a novel tyrosine kinase substrate, exhibits transforming activity, Mol. Cell. Biol., 13, 5814, 10.1128/MCB.13.9.5814 · DOI
  6. Wong, 1994, The human eps15 gene, encoding a tyrosine kinase substrate, is conserved in evolution and maps to 1p31-p32, Oncogene, 9, 1591
  7. Wong, 1995, A protein-binding domain, EH, identified in the receptor tyrosine kinase substrate Eps15 and conserved in evolution, Proc. Natl. Acad. Sci. USA, 92, 9530, 10.1073/pnas.92.21.9530 · DOI
  8. Di Fiore, 1997, EH: A novel protein–protein interaction domain potentially involved in intracellular sorting, Trends Biochem. Sci., 22, 411, 10.1016/S0968-0004(97)01127-4 · DOI
  9. Mayer, 1999, Endocytosis: EH domains lend a hand, Curr. Biol., 9, R70, 10.1016/S0960-9822(99)80014-1 · DOI
  10. de Beer, 1998, Structure and Asn-Pro-Phe binding pocket of the Eps15 homology domain, Science, 281, 1357, 10.1126/science.281.5381.1357 · DOI
  11. Whitehead, 1999, The EH1 domain of Eps15 is structurally classified as a member of the S100 subclass of EF-hand-containing proteins, Biochemistry, 38, 11271, 10.1021/bi990922i · DOI
  12. Koshiba, 1999, Solution structure of the Eps15 homology domain of a human POB1 (partner of RalBP1), FEBS Lett., 442, 138, 10.1016/S0014-5793(98)01644-5 · DOI
  13. Salcini, 1997, Binding specificity and in vivo targets of the EH domain, a novel protein–protein interaction module, Genes Dev., 11, 2239, 10.1101/gad.11.17.2239 · DOI · Paper page
  14. Paoluzi, 1998, Recognition specificity of individual EH domains of mammals and yeast, EMBO J., 17, 6541, 10.1093/emboj/17.22.6541 · DOI
  15. Yamabhai, 1998, Intersectin, a novel adaptor protein with two Eps15 homology and five Src homology 3 domains, J. Biol. Chem., 273, 31401, 10.1074/jbc.273.47.31401 · DOI · Paper page
  16. Wilson, 1997, The ‘Asx-Pro turn’ as a local structural motif stabilized by alternative patterns of hydrogen bonds and a consensus-derived model of the sequence Asn-Pro-Asn, Protein Eng., 10, 519, 10.1093/protein/10.5.519 · DOI
  17. Coda, 1998, Eps15R is a tyrosine kinase substrate with characteristics of a docking protein possibly involved in coated pits-mediated internalization, J. Biol. Chem., 273, 3003, 10.1074/jbc.273.5.3003 · DOI
  18. Sengar, 1999, The EH and SH3 domain Ese proteins regulate endocytosis by linking to dynamin and Eps15, EMBO J., 18, 1159, 10.1093/emboj/18.5.1159 · DOI
  19. Tebar, 1997, Eps15 is constitutively oligomerized due to homophilic interaction of its coiled-coil region, J. Biol. Chem., 272, 15413, 10.1074/jbc.272.24.15413 · DOI
  20. Cupers, 1997, Parallel dimers and anti-parallel tetramers formed by epidermal growth factor receptor pathway substrate clone 15, J. Biol. Chem., 272, 33430, 10.1074/jbc.272.52.33430 · DOI
  21. Gallusser, 1993, The beta 1 and beta 2 subunits of the AP complexes are the clathrin coat assembly components, EMBO J., 12, 5237, 10.1002/j.1460-2075.1993.tb06219.x · DOI
  22. Ohno, 1995, Interaction of tyrosine-based sorting signals with clathrin-associated proteins, Science, 269, 1872, 10.1126/science.7569928 · DOI
  23. Boll, 1996, Sequence requirements for the recognition of tyrosine-based endocytic signals by clathrin AP-2 complexes, EMBO J., 15, 5789, 10.1002/j.1460-2075.1996.tb00965.x · DOI · Paper page
  24. Owen, 1998, A structural explanation for the recognition of tyrosine-based endocytotic signals, Science, 282, 1327, 10.1126/science.282.5392.1327 · DOI
  25. Traub, 1999, Crystal structure of the alpha appendage of AP-2 reveals a recruitment platform for clathrin-coat assembly, Proc. Natl. Acad. Sci. USA, 96, 8907, 10.1073/pnas.96.16.8907 · DOI
  26. Tebar, 1996, Eps15 is a component of clathrin-coated pits and vesicles and is located at the rim of coated pits, J. Biol. Chem., 271, 28727, 10.1074/jbc.271.46.28727 · DOI
  27. Benmerah, 1995, The tyrosine kinase substrate eps15 is constitutively associated with the plasma membrane adaptor AP-2, J. Cell Biol., 131, 1831, 10.1083/jcb.131.6.1831 · DOI
  28. Benmerah, 1996, The ear of alpha-adaptin interacts with the COOH-terminal domain of the Eps 15 protein, J. Biol. Chem., 271, 12111, 10.1074/jbc.271.20.12111 · DOI
  29. Iannolo, 1997, Mapping of the molecular determinants involved in the interaction between eps15 and AP-2, Cancer Res., 57, 240
  30. Wang, 1995, The appendage domain of alpha-adaptin is a high affinity binding site for dynamin, J. Biol. Chem., 270, 10079, 10.1074/jbc.270.17.10079 · DOI
  31. David, 1996, A role of amphiphysin in synaptic vesicle endocytosis suggested by its binding to dynamin in nerve terminals, Proc. Natl. Acad. Sci. USA, 93, 331, 10.1073/pnas.93.1.331 · DOI
  32. Wigge, 1997, Inhibition of receptor-mediated endocytosis by the amphiphysin SH3 domain, Curr. Biol., 7, 554, 10.1016/S0960-9822(06)00254-5 · DOI
  33. Chen, 1998, Epsin is an EH-domain-binding protein implicated in clathrin-mediated endocytosis, Nature, 394, 793, 10.1038/28660 · DOI
  34. Owen, 1999, A structural explanation for the binding of multiple ligands by the alpha-adaptin appendage domain, Cell, 97, 805, 10.1016/S0092-8674(00)80791-6 · DOI
  35. Schumacher, 1995, The SH3 domain of Crk binds specifically to a conserved proline-rich motif in Eps15 and Eps15R, J. Biol. Chem., 270, 15341, 10.1074/jbc.270.25.15341 · DOI
  36. van Delft, 1997, Association and colocalization of Eps15 with adaptor protein-2 and clathrin, J. Cell Biol., 136, 811, 10.1083/jcb.136.4.811 · DOI
  37. Torrisi, 1999, Eps15 is recruited to the plasma membrane upon epidermal growth factor receptor activation and localizes to components of the endocytic pathway during receptor internalization, Mol. Biol. Cell, 10, 417, 10.1091/mbc.10.2.417 · DOI
  38. Cupers, 1998, Assembly of clathrin coats disrupts the association between Eps15 and AP-2 adaptors, J. Biol. Chem., 273, 1847, 10.1074/jbc.273.4.1847 · DOI · Paper page
  39. Carbone, 1997, eps15 and eps15R are essential components of the endocytic pathway, Cancer Res., 57, 5498
  40. Benmerah, 1998, AP-2/Eps15 interaction is required for receptor-mediated endocytosis, J. Cell Biol., 140, 1055, 10.1083/jcb.140.5.1055 · DOI
  41. Clark, 1997, A dynamin GTPase mutation causes a rapid and reversible temperature-inducible locomotion defect in C, elegans. Proc. Natl. Acad. Sci. USA, 94, 10438, 10.1073/pnas.94.19.10438 · DOI
  42. van Delft, 1997, Epidermal growth factor induces ubiquitination of Eps15, J. Biol. Chem., 272, 14013, 10.1074/jbc.272.22.14013 · DOI
  43. Roth, 1996, Ubiquitination of the yeast a-factor receptor, J. Cell Biol., 134, 661, 10.1083/jcb.134.3.661 · DOI
  44. Strous, 1996, The ubiquitin conjugation system is required for ligand-induced endocytosis and degradation of the growth hormone receptor, EMBO J., 15, 3806, 10.1002/j.1460-2075.1996.tb00754.x · DOI
  45. Hicke, 1996, Ubiquitination of a yeast plasma membrane receptor signals its ligand- stimulated endocytosis, Cell, 84, 277, 10.1016/S0092-8674(00)80982-4 · DOI · Paper page
  46. Slepnev, 1998, Role of phosphorylation in regulation of the assembly of endocytic coat complexes, Science, 281, 821, 10.1126/science.281.5378.821 · DOI
  47. Bernard, 1994, A novel gene, AF-1p, fused to HRX in t(1;11) (p32;q23), is not related to AF-4, AF-9 nor ENL, Oncogene, 9, 1039
  48. Rogaia, 1997, The localization of the HRX/ALL1 protein to specific nuclear subdomains is altered by fusion with its eps15 translocation partner, Cancer Res., 57, 799
  49. Okamoto, 1999, EHSH1/Intersectin, a protein that contains EH and SH3 domains and binds to dynamin and SNAP-25. A protein connection between exocytosis and endocytosis, J. Biol. Chem., 274, 18446, 10.1074/jbc.274.26.18446 · DOI
  50. Guipponi, 1998, Two isoforms of a human Intersectin (ITSN) protein are produced by brain-specific alternative splicing in a stop codon, Genomics, 53, 369, 10.1006/geno.1998.5521 · DOI
  51. Hussain, 1999, Splice variants of Intersectin are components of the endocytic machinery in neurons and nonneuronal cells, J. Biol. Chem., 274, 15671, 10.1074/jbc.274.22.15671 · DOI
  52. Roos, 1998, Dap160, a neural-specific Eps15 homology and multiple SH3 domain-containing protein that interacts with Drosophila dynamin, J. Biol. Chem., 273, 19108, 10.1074/jbc.273.30.19108 · DOI
  53. Cantor, 1995, Identification and characterization of Ral-binding protein 1, a potential downstream target of Ral GTPases, Mol. Cell. Biol., 15, 4578, 10.1128/MCB.15.8.4578 · DOI · Paper page
  54. Jullien-Flores, 1995, Bridging Ral GTPase to Rho pathways. RLIP76, a Ral effector with CDC42/Rac GTPase-activating protein activity, J. Biol. Chem., 270, 22473, 10.1074/jbc.270.38.22473 · DOI · Paper page
  55. Park, 1995, A putative effector of Ral has homology to Rho/Rac GTPase activating proteins, Oncogene, 11, 2349
  56. Yamaguchi, 1997, An Eps homology (EH) domain protein that binds to the Ral-GTPase target, RalBP1, J. Biol. Chem., 272, 31230, 10.1074/jbc.272.50.31230 · DOI · Paper page
  57. Ikeda, 1998, Identification and characterization of a novel protein interacting with Ral-binding protein 1, a putative effector protein of Ral, J. Biol. Chem., 273, 814, 10.1074/jbc.273.2.814 · DOI · Paper page
  58. Nakashima, 1999, Small G protein ral and its downstream molecules regulate endocytosis of EGF and insulin receptors, EMBO J., 18, 3629, 10.1093/emboj/18.13.3629 · DOI · Paper page
  59. Morinaka, 1999, Epsin binds to the EH domain of POB1 and regulates receptor-mediated endocytosis, Oncogene, 10.1038/sj.onc.1202974 · DOI
  60. Mintz, 1999, EHD1—An EH-domain-containing protein with a specific expression pattern, Genomics, 59, 66, 10.1006/geno.1999.5800 · DOI · Paper page
  61. Page, 1999, gamma-Synergin. An eh domain-containing protein that interacts with gamma-adaptin, J. Cell Biol., 146, 993, 10.1083/jcb.146.5.993 · DOI
  62. Wendland, 1996, A novel fluorescence-activated cell sorter-based screen for yeast endocytosis mutants identifies a yeast homologue of mammalian eps15, J. Cell Biol., 135, 1485, 10.1083/jcb.135.6.1485 · DOI
  63. Raths, 1993, Two mutants defective in receptor-mediated and fluid-phase endocytosis in Saccharomyces cerevisiae, J. Cell Biol., 120, 55, 10.1083/jcb.120.1.55 · DOI
  64. Benedetti, 1994, The END3 gene encodes a protein that is required for the internalization step of endocytosis and for actin cytoskeleton organization in yeast, Mol. Biol. Cell, 5, 1023, 10.1091/mbc.5.9.1023 · DOI
  65. Kolling, 1994, The ABC-transporter Ste6 accumulates in the plasma membrane in a ubiquitinated form in endocytosis mutants, EMBO J., 13, 3261, 10.1002/j.1460-2075.1994.tb06627.x · DOI
  66. Volland, 1994, Endocytosis and degradation of the yeast uracil permease under adverse conditions, J. Biol. Chem., 269, 9833, 10.1016/S0021-9258(17)36959-4 · DOI
  67. Lai, 1995, Regulation of inositol transport in Saccharomyces cerevisiae involves inositol-induced changes in permease stability and endocytic degradation in the vacuole, J. Biol. Chem., 270, 2525, 10.1074/jbc.270.6.2525 · DOI
  68. Tang, 1997, EH domain proteins Pan1p and End3p are components of a complex that plays a dual role in organization of the cortical actin cytoskeleton and endocytosis in Saccharomyces cerevisiae, Mol. Cell. Biol., 17, 4294, 10.1128/MCB.17.8.4294 · DOI
  69. Tang, 1996, The EH-domain-containing protein Pan1 is required for normal organization of the actin cytoskeleton in Saccharomyces cerevisiae, Mol. Cell. Biol., 16, 4897, 10.1128/MCB.16.9.4897 · DOI
  70. Wendland, 1998, Pan1p, yeast eps15, functions as a multivalent adaptor that coordinates protein–protein interactions essential for endocytosis, J. Cell Biol., 141, 71, 10.1083/jcb.141.1.71 · DOI
  71. Zolladek, 1997, MDP1, a Saccharomyces cerevisiae gene involved in mitochondrial/cytoplasmic protein distribution, is identical to the ubiquitin–protein ligase gene RSP5, Genetics, 145, 595, 10.1093/genetics/145.3.595 · DOI
  72. Tan, 1996, The sequence NPFXD defines a new class of endocytosis signal in Saccharomyces cerevisiae, J. Cell Biol., 135, 1789, 10.1083/jcb.135.6.1789 · DOI
  73. Uemura, 1989, numb, a gene required in determination of cell fate during sensory organ formation in Drosophila embryos, Cell, 58, 349, 10.1016/0092-8674(89)90849-0 · DOI
  74. Rhyu, 1994, Asymmetric distribution of numb protein during division of the sensory organ precursor cell confers distinct fates to daughter cells, Cell, 76, 477, 10.1016/0092-8674(94)90112-0 · DOI
  75. Verdi, 1996, Mammalian NUMB is an evolutionarily conserved signaling adapter protein that specifies cell fate, Curr. Biol., 6, 1134, 10.1016/S0960-9822(02)70680-5 · DOI
  76. Zhong, 1996, Asymmetric localization of a mammalian numb homolog during mouse cortical neurogenesis, Neuron, 17, 43, 10.1016/S0896-6273(00)80279-2 · DOI
  77. Zhong, 1997, Differential expression of mammalian Numb, Numblike and Notch1 suggests distinct roles during mouse cortical neurogenesis, Development, 124, 1887, 10.1242/dev.124.10.1887 · DOI
  78. Ruiz Gomez, 1997, Segregation of myogenic lineages in Drosophila requires numb, Development, 124, 4857, 10.1242/dev.124.23.4857 · DOI
  79. Carmena, 1998, Inscuteable and numb mediate asymmetric muscle progenitor cell divisions during Drosophila myogenesis, Genes Dev., 12, 304, 10.1101/gad.12.3.304 · DOI
  80. Knoblich, 1995, Asymmetric segregation of Numb and Prospero during cell division, Nature, 377, 624, 10.1038/377624a0 · DOI
  81. Kraut, 1996, Role of inscuteable in orienting asymmetric cell divisions in Drosophila, Nature, 383, 50, 10.1038/383050a0 · DOI
  82. Lu, 1998, Partner of Numb colocalizes with Numb during mitosis and directs Numb asymmetric localization in Drosophila neural and muscle progenitors, Cell, 95, 225, 10.1016/S0092-8674(00)81753-5 · DOI
  83. Campos-Ortega, 1996, Numb diverts notch pathway off the tramtrack, Neuron, 17, 1, 10.1016/S0896-6273(00)80274-3 · DOI
  84. Frise, 1996, The Drosophila Numb protein inhibits signaling of the Notch receptor during cell–cell interaction in sensory organ lineage, Proc. Natl. Acad. Sci. USA, 93, 11925, 10.1073/pnas.93.21.11925 · DOI
  85. Guo, 1996, Control of daughter cell fates during asymmetric division: Interaction of Numb and Notch, Neuron, 17, 27, 10.1016/S0896-6273(00)80278-0 · DOI
  86. Spana, 1996, Numb antagonizes Notch signaling to specify sibling neuron cell fates, Neuron, 17, 21, 10.1016/S0896-6273(00)80277-9 · DOI
  87. Wakamatsu, 1999, NUMB localizes in the basal cortex of mitotic avian neuroepithelial cells and modulates neuronal differentiation by binding to NOTCH-1, Neuron, 23, 71, 10.1016/S0896-6273(00)80754-0 · DOI
  88. Artavanis-Tsakonas, 1995, Notch signaling, Science, 268, 225, 10.1126/science.7716513 · DOI
  89. Greenwald, 1998, LIN-12/Notch signaling: Lessons from worms and flies, Genes Dev., 12, 1751, 10.1101/gad.12.12.1751 · DOI
  90. Artavanis-Tsakonas, 1999, Notch signaling: Cell fate control and signal integration in development, Science, 284, 770, 10.1126/science.284.5415.770 · DOI · Paper page
  91. Verdi, 1999, Distinct human NUMB isoforms regulate differentiation vs proliferation in the neuronal lineage, Proc. Natl. Acad. Sci. USA, 96, 10472, 10.1073/pnas.96.18.10472 · DOI
  92. Bogerd, 1995, Identification of a novel cellular cofactor for the Rev/Rex class of retroviral regulatory proteins, Cell, 82, 485, 10.1016/0092-8674(95)90437-9 · DOI
  93. Fritz, 1995, A human nucleoporin-like protein that specifically interacts with HIV Rev, Nature, 376, 530, 10.1038/376530a0 · DOI
  94. Fischer, 1995, The HIV-1 Rev activation domain is a nuclear export signal that accesses an export pathway used by specific cellular RNAs, Cell, 82, 475, 10.1016/0092-8674(95)90436-0 · DOI
  95. Fritz, 1996, HIV Rev uses a conserved cellular protein export pathway for the nucleocytoplasmic transport of viral RNAs, Curr. Biol., 6, 848, 10.1016/S0960-9822(02)00608-5 · DOI
  96. Stutz, 1996, A role for nucleoporin FG repeat domains in export of human immunodeficiency virus type 1 Rev protein and RNA from the nucleus, Mol. Cell. Biol., 16, 7144, 10.1128/MCB.16.12.7144 · DOI
  97. Roth, 1998, Nucleo-cytoplasmic shuttling of the hdm2 oncoprotein regulates the levels of the p53 protein via a pathway used by the human immunodeficiency virus rev protein, EMBO J., 17, 554, 10.1093/emboj/17.2.554 · DOI · Paper page
  98. Cullen, 1998, HIV-1 auxiliary proteins: Making connections in a dying cell, Cell, 93, 685, 10.1016/S0092-8674(00)81431-2 · DOI
  99. Stutz, 1995, Identification of a novel nuclear pore-associated protein as a functional target of the HIV-1 Rev protein in yeast, Cell, 82, 495, 10.1016/0092-8674(95)90438-7 · DOI
  100. Neville, 1997, The importin-beta family member Crm1p bridges the interaction between Rev and the nuclear pore complex during nuclear export, Curr. Biol., 7, 767, 10.1016/S0960-9822(06)00335-6 · DOI · Paper page
  101. Henderson, 1997, Interactions between HIV Rev and nuclear import and export factors: The Rev nuclear localisation signal mediates specific binding to human importin-beta, J. Mol. Biol., 274, 693, 10.1006/jmbi.1997.1420 · DOI
  102. Stade, 1997, Exportin 1 (Crm1p) is an essential nuclear export factor, Cell, 90, 1041, 10.1016/S0092-8674(00)80370-0 · DOI
  103. Fornerod, 1997, CRM1 is an export receptor for leucine-rich nuclear export signals, Cell, 90, 1051, 10.1016/S0092-8674(00)80371-2 · DOI
  104. Fukuda, 1997, CRM1 is responsible for intracellular transport mediated by the nuclear export signal, Nature, 390, 308, 10.1038/36894 · DOI
  105. Ossareh-Nazari, 1997, Evidence for a role of CRM1 in signal-mediated nuclear protein export, Science, 278, 141, 10.1126/science.278.5335.141 · DOI
  106. Ullman, 1997, Nuclear export receptors: From importin to exportin, Cell, 90, 967, 10.1016/S0092-8674(00)80361-X · DOI
  107. Stutz, 1997, The yeast nucleoporin rip1p contributes to multiple export pathways with no essential role for its FG-repeat region, Genes Dev., 11, 2857, 10.1101/gad.11.21.2857 · DOI
  108. Stukenberg, 1997, Systematic identification of mitotic phosphoproteins, Curr. Biol., 7, 338, 10.1016/S0960-9822(06)00157-6 · DOI
  109. Kay, 1999, Identification of a novel domain shared by putative components of the endocytic and cytoskeletal machinery, Protein Sci., 8, 435, 10.1110/ps.8.2.435 · DOI
  110. McPherson, 1998, EH domain-dependent interactions between Eps15 and clathrin-coated vesicle protein p95, Biochem. Biophys. Res. Commun., 244, 701, 10.1006/bbrc.1998.8331 · DOI
  111. Haffner, 1997, Synaptojanin 1: Localization on coated endocytic intermediates in nerve terminals and interaction of its 170 kDa isoform with Eps15, FEBS Lett., 419, 175, 10.1016/S0014-5793(97)01451-8 · DOI
  112. McPherson, 1996, A presynaptic inositol-5-phosphatase, Nature, 379, 353, 10.1038/379353a0 · DOI
  113. Nemoto, 1997, Synaptojanin 2, a novel synaptojanin isoform with a distinct targeting domain and expression pattern, J. Biol. Chem., 272, 30817, 10.1074/jbc.272.49.30817 · DOI
  114. Khvotchev, 1998, Developmentally regulated alternative splicing in a novel synaptojanin, J. Biol. Chem., 273, 2306, 10.1074/jbc.273.4.2306 · DOI
  115. Ramjaun, 1996, Tissue-specific alternative splicing generates two synaptojanin isoforms with differential membrane binding properties, J. Biol. Chem., 271, 24856, 10.1074/jbc.271.40.24856 · DOI
  116. Woscholski, 1997, Inositol lipid 5-phosphatases—Traffic signals and signal traffic, Trends Biochem. Sci., 22, 427, 10.1016/S0968-0004(97)01120-1 · DOI
  117. Mitchell, 1996, Regulation of second messengers by the inositol polyphosphate 5-phosphatases, Biochem. Soc. Trans., 24, 994, 10.1042/bst0240994 · DOI
  118. Sakisaka, 1997, Phosphatidylinositol 4,5-bisphosphate phosphatase regulates the rearrangement of actin filaments, Mol. Cell. Biol., 17, 3841, 10.1128/MCB.17.7.3841 · DOI
  119. McPherson, 1994, p145, a major Grb2-binding protein in brain, is co-localized with dynamin in nerve terminals where it undergoes activity-dependent dephosphorylation, J. Biol. Chem., 269, 30132, 10.1016/S0021-9258(18)43787-8 · DOI
  120. Ramjaun, 1997, Identification and characterization of a nerve terminal-enriched amphiphysin isoform, J. Biol. Chem., 272, 16700, 10.1074/jbc.272.26.16700 · DOI · Paper page
  121. Ringstad, 1997, The SH3p4/Sh3p8/SH3p13 protein family: Binding partners for synaptojanin and dynamin via a Grb2-like Src homology 3 domain, Proc. Natl. Acad. Sci. USA, 94, 8569, 10.1073/pnas.94.16.8569 · DOI
  122. de Heuvel, 1997, Identification of the major synaptojanin-binding proteins in brain, J. Biol. Chem., 272, 8710, 10.1074/jbc.272.13.8710 · DOI
  123. Qualmann, 1999, Syndapin I, a synaptic dynamin-binding protein that associates with the neural Wiskott–Aldrich syndrome protein, Mol. Biol. Cell, 10, 501, 10.1091/mbc.10.2.501 · DOI
  124. Srinivasan, 1997, Disruption of three phosphatidylinositol-polyphosphate 5-phosphatase genes from Saccharomyces cerevisiae results in pleiotropic abnormalities of vacuole morphology, cell shape, and osmohomeostasis, Eur. J. Cell Biol., 74, 350
  125. Stolz, 1998, Identification and characterization of an essential family of inositol polyphosphate 5-phosphatases (INP51, INP52 and INP53 gene products) in the yeast Saccharomyces cerevisiae, Genetics, 148, 1715, 10.1093/genetics/148.4.1715 · DOI
  126. Singer-Kruger, 1998, Synaptojanin family members are implicated in endocytic membrane traffic in yeast, J. Cell Sci., 111, 3347, 10.1242/jcs.111.22.3347 · DOI
  127. Ahle, 1986, Purification and properties of a new clathrin assembly protein, EMBO J., 5, 3143, 10.1002/j.1460-2075.1986.tb04621.x · DOI
  128. Keen, 1987, Clathrin assembly proteins: Affinity purification and a model for coat assembly, J. Cell Biol., 105, 1989, 10.1083/jcb.105.5.1989 · DOI
  129. Kohtz, 1988, A neuronal protein (NP185) associated with clathrin-coated vesicles. Characterization of NP185 with monoclonal antibodies, J. Biol. Chem., 263, 7418, 10.1016/S0021-9258(18)68658-2 · DOI
  130. Zhou, 1992, Characterization of a novel synapse-specific protein. II. cDNA cloning and sequence analysis of the F1-20 protein, J. Neurosci., 12, 2144, 10.1523/JNEUROSCI.12-06-02144.1992 · DOI
  131. Zhang, 1998, Synaptic vesicle size and number are regulated by a clathrin adaptor protein required for endocytosis, Neuron, 21, 1465, 10.1016/S0896-6273(00)80664-9 · DOI · Paper page
  132. Perry, 1991, Neuronal protein NP185 in avian and murine cerebellum: Expression during development and evidence for its presence in nerve endings, J. Histochem. Cytochem., 39, 1461, 10.1177/39.11.1918924 · DOI
  133. Sousa, 1992, Characterization of a novel synapse-specific protein. I. Developmental expression and cellular localization of the F1-20 protein and mRNA, J. Neurosci., 12, 2130, 10.1523/JNEUROSCI.12-06-02130.1992 · DOI
  134. Morris, 1993, Clathrin assembly protein AP180: Primary structure, domain organization and identification of a clathrin binding site, EMBO J., 12, 667, 10.1002/j.1460-2075.1993.tb05700.x · DOI
  135. Ye, 1995, Clathrin binding and assembly activities of expressed domains of the synapse-specific clathrin assembly protein AP-3, J. Biol. Chem., 270, 10933, 10.1074/jbc.270.18.10933 · DOI
  136. Ye, 1995, Inhibition of clathrin assembly by high affinity binding of specific inositol polyphosphates to the synapse-specific clathrin assembly protein AP-3, J. Biol. Chem., 270, 1564, 10.1074/jbc.270.4.1564 · DOI
  137. Hao, 1997, Regulation of AP-3 function by inositides. Identification of phosphatidylinositol 3,4,5-trisphosphate as a potent ligand, J. Biol. Chem., 272, 6393, 10.1074/jbc.272.10.6393 · DOI
  138. Dreyling, 1996, The t(10;11) (p13;q14) in the U937 cell line results in the fusion of the AF10 gene and CALM, encoding a new member of the AP-3 clathrin assembly protein family, Proc. Natl. Acad. Sci. USA, 93, 4804, 10.1073/pnas.93.10.4804 · DOI · Paper page
  139. Tebar, 1999, Clathrin assembly lymphoid myeloid leukemia (CALM) protein: Localization in endocytic-coated pits, interactions with clathrin, and the impact of overexpression on clathrin-mediated traffic, Mol. Biol. Cell, 10, 2687, 10.1091/mbc.10.8.2687 · DOI · Paper page
  140. Lohi, 1998, EAST, a novel EGF receptor substrate, associates with focal adhesions and actin fibers, FEBS Lett., 436, 419, 10.1016/S0014-5793(98)01171-5 · DOI
  141. Ponting, 1999, SMART: Identification and annotation of domains from signaling and extracellular protein sequences, Nucleic Acids Res., 27, 229, 10.1093/nar/27.1.229 · DOI
  142. Lohi, 1998, EAST, an epidermal growth factor receptor- and Eps15-associated protein with Src homology 3 and tyrosine-based activation motif domains, J. Biol. Chem., 273, 21408, 10.1074/jbc.273.33.21408 · DOI
  143. Piper, 1995, VPS27 controls vacuolar and endocytic traffic through a prevacuolar compartment in Saccharomyces cerevisiae, J. Cell Biol., 131, 603, 10.1083/jcb.131.3.603 · DOI
  144. Komada, 1995, Growth factor-induced tyrosine phosphorylation of Hrs, a novel 115-kilodalton protein with a structurally conserved putative zinc finger domain, Mol. Cell. Biol., 15, 6213, 10.1128/MCB.15.11.6213 · DOI · Paper page
  145. Takeshita, 1997, STAM, signal transducing adaptor molecule, is associated with Janus kinases and involved in signaling for cell growth and c-myc induction, Immunity, 6, 449, 10.1016/S1074-7613(00)80288-5 · DOI
  146. Asao, 1997, Hrs is associated with STAM, a signal-transducing adaptor molecule. Its suppressive effect on cytokine-induced cell growth, J. Biol. Chem., 272, 32785, 10.1074/jbc.272.52.32785 · DOI
  147. Patki, 1998, A functional PtdIns(3)P-binding motif, Nature, 394, 433, 10.1038/28771 · DOI
  148. Burd, 1998, Phosphatidylinositol(3)-phosphate signaling mediated by specific binding to RING FYVE domains, Mol. Cell, 2, 157, 10.1016/S1097-2765(00)80125-2 · DOI
  149. Simonsen, 1998, EEA1 links PI(3)K function to Rab5 regulation of endosome fusion, Nature, 394, 494, 10.1038/28879 · DOI · Paper page
  150. Benmerah, 1999, Inhibition of clathrin-coated pit assembly by an Eps15 mutant, J. Cell Sci., 112, 1303, 10.1242/jcs.112.9.1303 · DOI
  151. Chang, 1993, Ligand-induced internalization of the epidermal growth factor receptor is mediated by multiple endocytic codes analogous to the tyrosine motif found in constitutively internalized receptors, J. Biol. Chem., 268, 19312, 10.1016/S0021-9258(19)36515-9 · DOI
  152. Nesterov, 1995, Association of epidermal growth factor receptors with coated pit adaptins via a tyrosine phosphorylation-regulated mechanism, J. Biol. Chem., 270, 6320, 10.1074/jbc.270.11.6320 · DOI
  153. Mellman, 1996, Endocytosis and molecular sorting, Annu. Rev. Cell Dev. Biol., 12, 575, 10.1146/annurev.cellbio.12.1.575 · DOI
  154. Glickman, 1989, Specificity of binding of clathrin adaptors to signals on the mannose-6-phosphate/insulin-like growth factor II receptor, EMBO J., 8, 1041, 10.1002/j.1460-2075.1989.tb03471.x · DOI
  155. Nesterov, 1995, Ligand-induced endocytosis of epidermal growth factor receptors that are defective in binding adaptor proteins, Proc. Natl. Acad. Sci. USA, 92, 8719, 10.1073/pnas.92.19.8719 · DOI
  156. Sorkin, 1996, Epidermal growth factor receptor interaction with clathrin adaptors is mediated by the Tyr974-containing internalization motif, J. Biol. Chem., 271, 13377, 10.1074/jbc.271.23.13377 · DOI
  157. Nesterov, 1999, Inhibition of the receptor-binding function of clathrin adaptor protein AP-2 by dominant-negative mutant mu2 subunit and its effects on endocytosis, EMBO J., 18, 2489, 10.1093/emboj/18.9.2489 · DOI
  158. Dickson, 1983, Prelysosomal divergence of transferrin and epidermal growth factor during receptor-mediated endocytosis, Biochemistry, 22, 5667, 10.1021/bi00293a033 · DOI
  159. Hanover, 1985, Transit of receptors for epidermal growth factor and transferrin through clathrin-coated pits. Analysis of the kinetics of receptor entry, J. Biol. Chem., 260, 15938, 10.1016/S0021-9258(17)36349-4 · DOI
  160. Wiley, 1988, Anomalous binding of epidermal growth factor to A431 cells is due to the effect of high receptor densities and a saturable endocytic system, J. Cell Biol., 107, 801, 10.1083/jcb.107.2.801 · DOI
  161. Wiley, 1991, The role of tyrosine kinase activity in endocytosis, compartmentation, and down-regulation of the epidermal growth factor receptor, J. Biol. Chem., 266, 11083, 10.1016/S0021-9258(18)99131-3 · DOI
  162. Lund, 1990, Quantitative analysis of the endocytic system involved in hormone-induced receptor internalization, J. Biol. Chem., 265, 15713, 10.1016/S0021-9258(18)55456-9 · DOI
  163. Lamaze, 1995, Recruitment of epidermal growth factor receptors into coated pits requires their activated tyrosine kinase, J. Cell Biol., 129, 47, 10.1083/jcb.129.1.47 · DOI
  164. Marsh, 1989, Virus entry into animal cells, Adv. Virus Res., 36, 107, 10.1016/S0065-3527(08)60583-7 · DOI
  165. Wendland, 1998, Protein traffic in the yeast endocytic and vacuolar protein sorting pathways, COCB, 10, 513
  166. Kubler, 1993, Actin and fimbrin are required for the internalization step of endocytosis in yeast, EMBO J., 12, 2855, 10.1002/j.1460-2075.1993.tb05947.x · DOI
  167. Lappalainen, 1997, Cofilin promotes rapid actin filament turnover in vivo, Nature, 388, 78, 10.1038/40418 · DOI
  168. Yang, 1999, Sla2p is associated with the yeast cortical actin cytoskeleton via redundant localization signals, Mol. Biol. Cell, 10, 2265, 10.1091/mbc.10.7.2265 · DOI
  169. Lamaze, 1997, The actin cytoskeleton is required for receptor-mediated endocytosis in mammalian cells, J. Biol. Chem., 272, 20332, 10.1074/jbc.272.33.20332 · DOI
  170. Gaidarov, 1999, Spatial control of coated-pit dynamics in living cells, NCB, 1, 1
  171. Witke, 1998, In mouse brain profilin I and profilin II associate with regulators of the endocytic pathway and actin assembly, EMBO J., 17, 967, 10.1093/emboj/17.4.967 · DOI
  172. She, 1997, Wiskott–Aldrich syndrome protein is associated with the adapter protein Grb2 and the epidermal growth factor receptor in living cells, Mol. Biol. Cell, 8, 1709, 10.1091/mbc.8.9.1709 · DOI
  173. Simpson, 1999, SH3-domain-containing proteins function at distinct steps in clathrin-coated vesicle formation, NCB, 1, 119
  174. Wendland, 1999, Yeast Epsins contain an essential N-terminal ENTH domain, bind clathrin and are required for endocytosis, EMBO J., 18, 4383, 10.1093/emboj/18.16.4383 · DOI
  175. Merilainen, 1997, FAP52, a novel, SH3 domain-containing focal adhesion protein, J. Biol. Chem., 272, 23278, 10.1074/jbc.272.37.23278 · DOI
  176. Floyd, 1998, Trends Cell Biol., 8, 299, 10.1016/S0962-8924(98)01316-6 · DOI
  177. Di Fiore, 1999, Endocytosis and mitogenic signaling, Curr. Opin. Cell Biol., 11, 483, 10.1016/S0955-0674(99)80069-6 · DOI
  178. Rowley, 1998, The critical role of chromosome translocations in human leukemias, Annu. Rev. Genet., 32, 495, 10.1146/annurev.genet.32.1.495 · DOI
  179. Schichman, 1994, ALL-1 partial duplication in acute leukemia, Proc. Natl. Acad. Sci. USA, 91, 6236, 10.1073/pnas.91.13.6236 · DOI
  180. Corral, 1996, An Mll-AF9 fusion gene made by homologous recombination causes acute leukemia in chimeric mice: A method to create fusion oncogenes, Cell, 85, 853, 10.1016/S0092-8674(00)81269-6 · DOI
  181. Djabali, 1992, A trithorax-like gene is interrupted by chromosome 11q23 translocations in acute leukaemias, Nat. Genet., 2, 113, 10.1038/ng1092-113 · DOI
  182. Iida, 1993, MLLT3 gene on 9p22 involved in t(9;11) leukemia encodes a serine/proline rich protein homologous to MLLT1 on 19p13, Oncogene, 8, 3085
  183. Dreyling, 1998, MLL and CALM are fused to AF10 in morphologically distinct subsets of acute leukemia with translocation t(10;11): Both rearrangements are associated with a poor prognosis, Blood, 91, 4662
  184. Levkowitz, 1998, c-Cbl/Sli-1 regulates endocytic sorting and ubiquitination of the epidermal growth factor receptor, Genes Dev., 12, 3663, 10.1101/gad.12.23.3663 · DOI
  185. Ohno, 1998, Nucleocytoplasmic transport: The last 200 nanometers, Cell, 92, 327, 10.1016/S0092-8674(00)80926-5 · DOI
  186. Freedman, 1998, Nuclear export is required for degradation of endogenous p53 by MDM2 and human papillomavirus E6, Mol. Cell. Biol., 18, 7288, 10.1128/MCB.18.12.7288 · DOI
  187. Juven-Gershon, 1998, The Mdm2 oncoprotein interacts with the cell fate regulator Numb, Mol. Cell. Biol., 18, 3974, 10.1128/MCB.18.7.3974 · DOI
  188. Prives, 1998, Signaling to p53: Breaking the MDM2-p53 circuit, Cell, 95, 5, 10.1016/S0092-8674(00)81774-2 · DOI · Paper page
  189. Juven-Gershon, 1999, Mdm2: The ups and downs, Mol. Med., 5, 71, 10.1007/BF03402141 · DOI
  190. Freedman, 1999, Functions of the MDM2 oncoprotein, Cell. Mol. Life Sci., 55, 96, 10.1007/s000180050273 · DOI
  191. ter Haar, 1998, Atomic structure of clathrin: A beta propeller terminal domain joins an alpha zigzag linker, Cell, 95, 563, 10.1016/S0092-8674(00)81623-2 · DOI
  192. Musacchio, 1999, Functional organization of clathrin in coats: Combining electron cryomicroscopy and X-ray crystallography, Mol. Cell, 3, 761, 10.1016/S1097-2765(01)80008-3 · DOI
  193. Marsh, 1999, The structural era of endocytosis, Science, 285, 215, 10.1126/science.285.5425.215 · DOI

Cited by

Sorted by citations

Metadata

Authors
Santolini, E., Salcini, A. E., Kay, B. K., Yamabhai, M., & Di Fiore, P. P.
Venue
Experimental Cell Research
Publisher
Elsevier BV
Published
1999-11
Volume
253
Issue
1
Pages
186-209
ISSN
0014-4827
DOI
10.1006/excr.1999.4694
Cited by
111
References
2
Language
en
Licence
www.elsevier.com/tdm/userlicense/1.0/ (tdm)

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review