Involvement of Oxidative Stress on the Impairment of Energy Metabolism Induced by Aβ Peptides on PC12 Cells: Protection by Antioxidants

Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays

Mosmann, T. (1983) · Journal of Immunological Methods · doi:10.1016/0022-1759(83)90303-4 · Cited by 56,104 · see citing works

Chemistry and biochemistry of 4-hydroxynonenal, malonaldehyde and related aldehydes

Esterbauer, H., Schaur, R. J., & Zollner, H. (1991) · Free Radical Biology and Medicine · doi:10.1016/0891-5849(91)90192-6 · Cited by 6,672 · see citing works

Establishment of a noradrenergic clonal line of rat adrenal pheochromocytoma cells which respond to nerve growth factor.

Greene, L., & Tischler, A. S. (1976) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.73.7.2424 · Cited by 5,594 · see citing works

The precursor of Alzheimer's disease amyloid A4 protein resembles a cell-surface receptor

Kang, J., Lemaire, H.-G., Unterbeck, A., Salbaum, J. M., Masters, C. L., Grzeschik, K.-H., Multhaup, G., Beyreuther, K., & Müller-Hill, B. (1987) · Nature · doi:10.1038/325733a0 · Cited by 4,619 · see citing works

A rapid, sensitive, and versatile assay for protein using Coomassie brilliant blue G250

SEDMAK, J. J., & Grossberg, S. E. (1977) · Analytical Biochemistry · doi:10.1016/0003-2697(77)90428-6 · Cited by 3,043 · see citing works

The molecular pathology of Alzheimer's disease

Selkoe, D. J. (1991) · Neuron · doi:10.1016/0896-6273(91)90052-2 · Cited by 2,708 · see citing works

Hydrogen peroxide mediates amyloid β protein toxicity

Behl, C. (1994) · Cell · doi:10.1016/0092-8674(94)90131-7 · Cited by 2,074 · see citing works

RAGE and amyloid-β peptide neurotoxicity in Alzheimer's disease

Yan, S. D., Chen, X., Fu, J., Chen, M., Zhu, H., Roher, A., Slattery, T., Zhao, L., Nagashima, M., Morser, J., et al. (1996) · Nature · doi:10.1038/382685a0 · Cited by 2,012 · see citing works

Neurotrophic and Neurotoxic Effects of Amyloid β Protein: Reversal by Tachykinin Neuropeptides

Yankner, B. A., Duffy, L. K., & Kirschner, D. A. (1990) · Science · doi:10.1126/science.2218531 · Cited by 1,975 · see citing works

Flow cytometric studies of oxidative product formation by neutrophils: a graded response to membrane stimulation.

Bass, D., Parce, J. W., DeChatelet, L. R., Szejda, P., Seeds, M. C., & Thomas, M. (1983) · The Journal of Immunology · doi:10.4049/jimmunol.130.4.1910 · Cited by 1,811 · see citing works

beta-Amyloid peptides destabilize calcium homeostasis and render human cortical neurons vulnerable to excitotoxicity

Mattson, M. P., Cheng, B., Davis, D. G., Bryant, K., Lieberburg, I. M., & Rydel, R. E. (1992) · Journal of Neuroscience · doi:10.1523/jneurosci.12-02-00376.1992 · Cited by 1,627 · see citing works

Neurodegeneration induced by beta-amyloid peptides in vitro: the role of peptide assembly state

Pike, C., Burdick, D., Walencewicz, A., Glabe, C., & Cotman, C. (1993) · The Journal of Neuroscience · doi:10.1523/jneurosci.13-04-01676.1993 · Cited by 1,417 · see citing works

Excess brain protein oxidation and enzyme dysfunction in normal aging and in Alzheimer disease.

Smith, C. D., Carney, J. M., Starke-Reed, P. E., Oliver, C. N., Stadtman, E. R., Floyd, R. A., & Markesbery, W. R. (1991) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.88.23.10540 · Cited by 1,296 · see citing works

A model for beta-amyloid aggregation and neurotoxicity based on free radical generation by the peptide: relevance to Alzheimer disease.

Hensley, K., Carney, J. M., Mattson, M. P., Aksenova, M., Harris, M., Wu, J. F., Floyd, R. A., & Butterfield, D. A. (1994) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.91.8.3270 · Cited by 1,086 · see citing works

Mechanisms of Neuronal Degeneration in Alzheimer's Disease

Yankner, B. A. (1996) · Neuron · doi:10.1016/s0896-6273(00)80115-4 · Cited by 947 · see citing works

Detection of picomole levels of hydroperoxides using a fluorescent dichlorofluorescein assay

Cathcart, R., Schwiers, E., & Ames, B. N. (1983) · Analytical Biochemistry · doi:10.1016/0003-2697(83)90270-1 · Cited by 857 · see citing works

Evidence that 4-Hydroxynonenal Mediates Oxidative Stress-Induced Neuronal Apoptosis

Kruman, I. I., Bruce‐Keller, A. J., Bredesen, D. E., Waeg, G., & Mattson, M. P. (1997) · Journal of Neuroscience · doi:10.1523/jneurosci.17-13-05089.1997 · Cited by 719 · see citing works

Advanced Maillard reaction end products are associated with Alzheimer disease pathology.

Smith, M. A., Taneda, S., Richey, P. L., Miyata, S., Yan, S. D., Stern, D., Sayre, L. M., Monnier, V. M., & Perry, G. L. (1994) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.91.12.5710 · Cited by 715 · see citing works

Four-hydroxynonenal, a product of lipid peroxidation, is increased in the brain in Alzheimer's disease

Markesbery, W. R., & Lovell, M. A. (1998) · Neurobiology of Aging · doi:10.1016/s0197-4580(98)00009-8 · Cited by 680 · see citing works

Elevated thiobarbituric acid-reactive substances and antioxidant enzyme activity in the brain in Alzheimer's disease

Lovell, M. A., Ehmann, W. D., Butler, S. M., & Markesbery, W. R. (1995) · Neurology · doi:10.1212/wnl.45.8.1594 · Cited by 644 · see citing works

Vitamin E protects nerve cells from amyloid βprotein toxicity

Behl, C., Davis, J. B., Cole, G. M., & Schubert, D. A. (1992) · Biochemical and Biophysical Research Communications · doi:10.1016/0006-291x(92)90837-b · Cited by 582 · see citing works

Amyloid beta-peptide impairs ion-motive ATPase activities: evidence for a role in loss of neuronal Ca2+ homeostasis and cell death

Mark, R. J., Hensley, K., Butterfield, D. A., & Mattson, M. P. (1995) · Journal of Neuroscience · doi:10.1523/jneurosci.15-09-06239.1995 · Cited by 553 · see citing works

Amyloid β-Peptide Impairs Glucose Transport in Hippocampal and Cortical Neurons: Involvement of Membrane Lipid Peroxidation

Mark, R. J., Pang, Z., Geddes, J. W., Uchida, K., & Mattson, M. P. (1997) · The Journal of Neuroscience · doi:10.1523/jneurosci.17-03-01046.1997 · Cited by 551 · see citing works

β-Amyloid precursor protein metabolites and loss of neuronal Ca2+ homeostasis in Alzheimer's disease

Mattson, M. P., Barger, S. W., Cheng, B., Lieberburg, I. M., Smith‐Swintosky, V. L., & Rydel, R. E. (1993) · Trends in Neurosciences · doi:10.1016/0166-2236(93)90009-b · Cited by 516 · see citing works

Excitatory amino acids and Alzheimer's disease

Greenamyre, J. T., & Young, A. B. (1989) · Neurobiology of Aging · doi:10.1016/0197-4580(89)90143-7 · Cited by 482 · see citing works

Radical AGEing in Alzheimer's disease

Smith, M. A., Sayre, L. M., Monnier, V. M., & Perry, G. L. (1995) · Trends in Neurosciences · doi:10.1016/0166-2236(95)93897-7 · Cited by 462 · see citing works

Secreted Forms of β-Amyloid Precursor Protein Protect Hippocampal Neurons against Amyloid β-Peptide-Induced Oxidative Injury

Goodman, Y., & Mattson, M. P. (1994) · Experimental Neurology · doi:10.1006/exnr.1994.1107 · Cited by 449 · see citing works

Impairment of Glucose and Glutamate Transport and Induction of Mitochondrial Oxidative Stress and Dysfunction in Synaptosomes by Amyloid β‐Peptide: Role of the Lipid Peroxidation Product 4‐Hydroxynonenal

Keller, J. N., Pang, Z., Geddes, J. W., Begley, J. G., Germeyer, A., Waeg, G., & Mattson, M. P. (1997) · Journal of Neurochemistry · doi:10.1046/j.1471-4159.1997.69010273.x · Cited by 439 · see citing works

Mitochondria: a practical approach.

Darley-Usmar, V. M., RICKWOOD, D., & Wilson, M. T. (1987) · IRL Press eBooks · Cited by 410 · see citing works

β-Amyloid Peptide Free Radical Fragments Initiate Synaptosomal Lipoperoxidation in a Sequence-Specific Fashion: Implications to Alzheimer′s Disease

Butterfield, D. A., Hensley, K., Harris‐White, M. E., Mattson, M. P., & Carney, J. M. (1994) · Biochemical and Biophysical Research Communications · doi:10.1006/bbrc.1994.1508 · Cited by 404 · see citing works

Amyloid peptides are toxic via a common oxidative mechanism.

Schubert, D. A., Behl, C., Lesley, R., Brack, A., Dargusch, R., Sagara, Y., & Kimura, H. (1995) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.92.6.1989 · Cited by 379 · see citing works

Pyruvate Protects Neurons against Hydrogen Peroxide-Induced Toxicity

Desagher, S., Glowinski, J., & Prémont, J. (1997) · Journal of Neuroscience · doi:10.1523/jneurosci.17-23-09060.1997 · Cited by 370 · see citing works

Alterations in mitochondrial membrane fluidity by lipid peroxidation products

Chen, J. J., & Yu, B. P. (1994) · Free Radical Biology and Medicine · doi:10.1016/0891-5849(94)90167-8 · Cited by 369 · see citing works

Bioenergetic and oxidative stress in neurodegenerative diseases

Bowling, A. C., & Beal, M. F. (1995) · Life Sciences · doi:10.1016/0024-3205(95)00055-b · Cited by 364 · see citing works

Melatonin Prevents Death of Neuroblastoma Cells Exposed to the Alzheimer Amyloid Peptide

Pappolla, M. A., Sos, M., Omar, R. A., Bick, R. J., Hickson-Bick, D. L. M., Reiter, R. J., Efthimiopoulos, S., & Robakis, N. K. (1997) · The Journal of Neuroscience · doi:10.1523/jneurosci.17-05-01683.1997 · Cited by 359 · see citing works

4-Hydroxynonenal, an aldehydic product of membrane lipid peroxidation, impairs glutamate transport and mitochondrial function in synaptosomes

Keller, J. N., Mark, R. J., Bruce‐Keller, A. J., Blanc, E. M., Rothstein, J. D., Uchida, K., Waeg, G., & Mattson, M. P. (1997) · Neuroscience · doi:10.1016/s0306-4522(97)00065-1 · Cited by 358 · see citing works

[18] Mitochondrial cytochrome c: Preparation and activity of native and chemically modified cytochromes c

Brautigan, D. L., Ferguson-Miller, S. M., & Margoliash, E. (1978) · Methods in enzymology on CD-ROM/Methods in enzymology · doi:10.1016/s0076-6879(78)53021-8 · Cited by 352 · see citing works

Simultaneous extraction and reverse-phase high-performance liquid chromatographic determination of adenine and pyridine nucleotides in human red blood cells

Stocchi, V., Cucchiarini, L., Magnani, M., Chiarantini, L., Palma, P., & Crescentini, G. (1985) · Analytical Biochemistry · doi:10.1016/0003-2697(85)90405-1 · Cited by 346 · see citing works

Amyloidogenicity of beta A4 and beta A4-bearing amyloid protein precursor fragments by metal-catalyzed oxidation.

Dyrks, T., Dyrks, E., Hartmann, T., Masters, C. L., & Beyreuther, K. T. (1992) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)37174-1 · Cited by 343 · see citing works

Reduced Glucose Transporter at the Blood‐Brain Barrier and in Cerebral Cortex in Alzheimer Disease

Kalaria, R. N., & Harik, S. I. (1989) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.1989.tb07399.x · Cited by 338 · see citing works

Chapter 10 Calcium, Free Radicals, and Excitotoxic Neuronal Death in Primary Cell Culture

Mattson, M. P., Barger, S. W., Begley, J. G., & Mark, R. J. (1995) · Methods in cell biology · doi:10.1016/s0091-679x(08)61930-5 · Cited by 334 · see citing works

Age- and peroxidative stress-related modifications of the cerebral enzymatic activities linked to mitochondria and the glutathione system

Benzi, G., & Moretti, A. (1995) · Free Radical Biology and Medicine · doi:10.1016/0891-5849(94)00244-e · Cited by 283 · see citing works

The Lipid Peroxidation Product, 4‐Hydroxy‐2‐<i>trans</i>‐Nonenal, Alters the Conformation of Cortical Synaptosomal Membrane Proteins

Subramaniam, R., Roediger, F., Jordan, B., Mattson, M. P., Keller, J. N., Waeg, G., & Butterfield, D. A. (1997) · Journal of Neurochemistry · doi:10.1046/j.1471-4159.1997.69031161.x · Cited by 270 · see citing works

Nitric oxide-mediated mitochondrial damage: A potential neuroprotective role for glutathione

Bolaños, J. P., Heales, S. J. R., Peuchen, S., Barker, J. E., Land, J. M., & Clark, J. B. (1996) · Free Radical Biology and Medicine · doi:10.1016/s0891-5849(96)00240-7 · Cited by 263 · see citing works

Deficits in cerebral glucose metabolism demonstrated by positron emission tomography in individuals at risk of familial Alzheimer's disease

Kennedy, A. M., Frackowiak, R. S. J., Newman, S. K., Bloomfield, P. M., Seaward, J., Roques, P., Lewington, G., Cunningham, V. J., & Rossor, M. N. (1995) · Neuroscience Letters · doi:10.1016/0304-3940(95)11270-7 · Cited by 250 · see citing works

The Hepatocellular Metabolism of 4-Hydroxynonenal by Alcohol Dehydrogenase, Aldehyde Dehydrogenase, and Glutathione S-Transferase

Hartley, D. P., Ruth, J. A., & Petersen, D. R. (1995) · Archives of Biochemistry and Biophysics · doi:10.1006/abbi.1995.1028 · Cited by 243 · see citing works

Ceramide Protects Hippocampal Neurons Against Excitotoxic and Oxidative Insults, and Amyloid β‐Peptide Toxicity

Goodman, Y., & Mattson, M. P. (1996) · Journal of Neurochemistry · doi:10.1046/j.1471-4159.1996.66020869.x · Cited by 231 · see citing works

Mitochondrial and glycolytic dysfunction in lethal injury to hepatocytes by t-butylhydroperoxide: protection by fructose, cyclosporin A and trifluoperazine.

Imberti, R., Nieminen, A. L., Herman, B. A., & Lemasters, J. J. (1993) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1016/s0022-3565(25)38135-8 · Cited by 219 · see citing works

[39] Preparation and properties of succinic—cytochrome c reductase (complex II–III)

Tisdale, H. D. (1967) · Methods in enzymology on CD-ROM/Methods in enzymology · doi:10.1016/0076-6879(67)10042-6 · Cited by 214 · see citing works

The Intracellular Component of Cellular 3‐(4,5‐Dimethylthiazol‐2‐yl)‐2,5‐Diphenyltetrazolium Bromide (MTT) Reduction Is Specifically Inhibited by β‐Amyloid Peptides

Shearman, M. S., Hawtin, S. R., & Tailor, V. J. (1995) · Journal of Neurochemistry · doi:10.1046/j.1471-4159.1995.65010218.x · Cited by 204 · see citing works

Diminished Glucose Transport in Alzheimer's Disease: Dynamic PET Studies

Jagust, W. J., Seab, J. P., Huesman, R. H., Valk, P. E., Mathis, C. A., Reed, B., Coxson, P. G., & Budinger, T. F. (1991) · Journal of Cerebral Blood Flow & Metabolism · doi:10.1038/jcbfm.1991.65 · Cited by 187 · see citing works

Amyloid β‐Peptide Induces Cell Monolayer Albumin Permeability, Impairs Glucose Transport, and Induces Apoptosis in Vascular Endothelial Cells

Blanc, E. M., Toborek, M. J., Mark, R. J., Hennig, B., & Mattson, M. P. (1997) · Journal of Neurochemistry · doi:10.1046/j.1471-4159.1997.68051870.x · Cited by 174 · see citing works

Amyloid β-peptide and oxidative cellular injury in Alzheimer’s disease

Mark, R. J., Blanc, E. M., & Mattson, M. P. (1996) · Molecular Neurobiology · doi:10.1007/bf02755589 · Cited by 129 · see citing works

Mitochondria: A practical approach

Cammack, R. (1988) · FEBS Letters · doi:10.1016/0014-5793(88)81388-7 · Cited by 129 · see citing works

Mitochondrial function impairment induced by amyloid β-peptide on PC12 cells

Pereira, C., Santos, M. S., & Oliveira, C. (1998) · NeuroReport · doi:10.1097/00001756-199806010-00015 · Cited by 115 · see citing works

Abnormalities of Glucose Metabolism in Alzheimer's Disease

Hoyer, S. (1991) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.1991.tb00190.x · Cited by 112 · see citing works

Protection Against Oxidative Stress‐induced Neuronal Cell Death‐A Novel Role for RU486

Behl, C., Trapp, T., Skutella, T., & Holsboer, F. (1997) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.1997.tb01442.x · Cited by 98 · see citing works

β-Amyloid toxicity in organotypic cultures : protection by EUK-8, a synthetic catalytic free radical scavenger

Bruce, A. F. (1996) · Medical Entomology and Zoology · Cited by 85 · see citing works

Amyloid β‐Mediated Oxidative and Metabolic Stress in Rat Cortical Neurons: No Direct Evidence for a Role for H2O2 Generation

Zhang, Z., Rydel, R. E., Drzewiecki, G. J., Fuson, K. S., Wright, S., Wogulis, M. D., Audia, J. E., May, P. C., & Hyslop, P. A. (1996) · Journal of Neurochemistry · doi:10.1046/j.1471-4159.1996.67041595.x · Cited by 66 · see citing works

Transforming growth factor-beta inhibition of cytokine-induced vascular cell adhesion molecule-1 expression in human astrocytes

Winkler, M. K., & Benveniste, E. N. (1998) · Glia · doi:10.1002/(sici)1098-1136(199802)22:2 · Cited by 50 · see citing works

Effect of Nerve Growth Factor on Glucose Utilization and Nucleotide Content of Pheochromocytoma Cells (Clone PC12)

Morelli, A. M., Grasso, M., & Calissano, P. (1986) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.1986.tb04512.x · Cited by 28 · see citing works

4-Hydroxy-2-Nonenal Hardly Affects Glycolysis

Miwa, I., Adachi, K., Murase, S., Hamada, Y., & Sugiura, M. (1997) · Free Radical Biology and Medicine · doi:10.1016/s0891-5849(97)00005-1 · Cited by 13 · see citing works

Altered glucose metabolism in Alzheimer's disease

Sims, N. R. (1990) · Annals of Neurology · doi:10.1002/ana.410270621 · Cited by 12 · see citing works

Role of Gqα in insulin-stimulated glucose uptake by C6 glioma cells

Singh, S., Gao, Y., Kunapuli, S. P., & Ravindra, R. (1997) · Neuroreport · doi:10.1097/00001756-199707070-00051 · Cited by 2 · see citing works

Curcumin has potent anti‐amyloidogenic effects for Alzheimer's β‐amyloid fibrils in vitro

Ono, K., Hasegawa, K., Naiki, H., & Yamada, M. (2004) · Journal of Neuroscience Research · doi:10.1002/jnr.20025 · Cited by 1,254 · see citing works

β-Amyloid Peptides Induce Mitochondrial Dysfunction and Oxidative Stress in Astrocytes and Death of Neurons through Activation of NADPH Oxidase

Abramov, A. Y., Canevari, L., & Duchen, M. R. (2004) · The Journal of Neuroscience · doi:10.1523/jneurosci.4042-03.2004 · Cited by 587 · see citing works

β‐Amyloid inhibits integrated mitochondrial respiration and key enzyme activities

Casley, C. S., Canevari, L., Land, J. M., Clark, J. B., & Sharpe, M. A. (2001) · Journal of Neurochemistry · doi:10.1046/j.0022-3042.2001.00681.x · Cited by 485 · see citing works

Why Women Have More Alzheimer's Disease Than Men: Gender and Mitochondrial Toxicity of Amyloid-β Peptide

Viña, J., & Lloret, A. (2010) · Journal of Alzheimer's Disease · doi:10.3233/jad-2010-100501 · Cited by 447 · see citing works

Modification of Brain Aging and Neurodegenerative Disorders by Genes, Diet, and Behavior

Mattson, M. P., Chan, S. L., & Duan, W. (2002) · Physiological Reviews · doi:10.1152/physrev.00004.2002 · Cited by 438 · see citing works

Oxidative injury in diseases of the central nervous system: focus on alzheimer’s disease

Praticò, D., & Delanty, N. (2000) · The American Journal of Medicine · doi:10.1016/s0002-9343(00)00547-7 · Cited by 378 · see citing works

Mitochondrial Approaches for Neuroprotection

Chaturvedi, R. K., & Beal, M. F. (2008) · Annals of the New York Academy of Sciences · doi:10.1196/annals.1427.027 · Cited by 294 · see citing works

Amyloid-β peptide induces oligodendrocyte death by activating the neutral sphingomyelinase–ceramide pathway

Lee, J.-T., Xu, J., Lee, J.-M., Ku, G., Han, X., Yang, D.-I., Chen, S., & Hsu, C. Y. (2004) · The Journal of Cell Biology · doi:10.1083/jcb.200307017 · Cited by 280 · see citing works

Oxidative stress and β-amyloid protein in Alzheimer’s disease

Cai, Z., Zhao, B., & Ratka, A. (2011) · NeuroMolecular Medicine · doi:10.1007/s12017-011-8155-9 · Cited by 279 · see citing works

Involvement of oxidative stress in the enhancement of acetylcholinesterase activity induced by amyloid beta-peptide

Melo, J. B., Agostinho, P. M., & Oliveira, C. R. (2002) · Neuroscience Research · doi:10.1016/s0168-0102(02)00201-8 · Cited by 271 · see citing works

Anti-amyloidogenic activity of tannic acid and its activity to destabilize Alzheimer's β-amyloid fibrils in vitro

Ono, K., Hasegawa, K., Naiki, H., & Yamada, M. (2004) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · doi:10.1016/j.bbadis.2004.06.008 · Cited by 264 · see citing works

Mitochondrial Dysfunction as a Driver of Cognitive Impairment in Alzheimer’s Disease

Sharma, C., Kim, S., Nam, Y., Jung, U. J., & Kim, S. R. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22094850 · Cited by 242 · see citing works

Neurotoxic effect of oligomeric and fibrillar species of amyloid-beta peptide 1-42: Involvement of endoplasmic reticulum calcium release in oligomer-induced cell death

Resende, R., Ferreiro, E., Pereira, C., & Resende de Oliveira, C. (2008) · Neuroscience · doi:10.1016/j.neuroscience.2008.06.036 · Cited by 235 · see citing works

The density of remaining nerve endings in human skin with and without postherpetic neuralgia after shingles

Oaklander, A. L. (2001) · Pain · doi:10.1016/s0304-3959(00)00481-4 · Cited by 233 · see citing works

Gradual Alteration of Mitochondrial Structure and Function by β-Amyloids: Importance of Membrane Viscosity Changes, Energy Deprivation, Reactive Oxygen Species Production, and Cytochrome c Release

Aleardi, A. M., Benard, G., Augereau, O., Malgat, M., Talbot, J.-C., Mazat, J., Letellier, T., Dachary-Prigent, J., Solaini, G., & Rossignol, R. (2005) · Journal of Bioenergetics and Biomembranes · doi:10.1007/s10863-005-6631-3 · Cited by 225 · see citing works

Mechanisms of Mitochondrial Dysfunction in Alzheimer’s Disease

Cadonic, C., Sabbir, M. G., & Albensi, B. C. (2016) · Molecular Neurobiology · doi:10.1007/s12035-015-9515-5 · Cited by 226 · see citing works

The release of calcium from the endoplasmic reticulum induced by amyloid-beta and prion peptides activates the mitochondrial apoptotic pathway

Ferreiro, E. B., Oliveira, C. R., & Pereira, C. (2008) · Neurobiology of Disease · doi:10.1016/j.nbd.2008.02.003 · Cited by 219 · see citing works

Neuronal Apoptosis in Neurodegeneration

Okouchi, M., Ekshyyan, O. Y., Maracine, M., & Aw, T. Y. (2007) · Antioxidants and Redox Signaling · doi:10.1089/ars.2007.1511 · Cited by 219 · see citing works

Mitochondrial alterations Alzheimer's disease

Baloyannis, S. J., Costa, V., & Michmizos, D. (2004) · American Journal of Alzheimer's Disease &amp; Other Dementias® · doi:10.1177/153331750401900205 · Cited by 206 · see citing works

β-Amyloid Fragment 25–35 Causes Mitochondrial Dysfunction in Primary Cortical Neurons

Casley, C. S., Land, J. M., Sharpe, M. A., Clark, J. B., Duchen, M. R., & Canevari, L. (2002) · Neurobiology of Disease · doi:10.1006/nbdi.2002.0516 · Cited by 205 · see citing works

Functional mitochondria are required for amyloid β‐mediated neurotoxicity

Cardoso, S. M., Santos, S., Swerdlow, R. H., & Oliveira, C. R. (2001) · The FASEB Journal · doi:10.1096/fj.00-0561fje · Cited by 203 · see citing works

An endoplasmic-reticulum-specific apoptotic pathway is involved in prion and amyloid-beta peptides neurotoxicity

Ferreiro, E. B., Resende, R., Costa, R. O., Oliveira, C. R., & Pereira, C. (2006) · Neurobiology of Disease · doi:10.1016/j.nbd.2006.05.011 · Cited by 199 · see citing works

Is reflex sympathetic dystrophy/complex regional pain syndrome type I a small‐fiber neuropathy?

Oaklander, A. L., & Fields, H. L. (2009) · Annals of Neurology · doi:10.1002/ana.21692 · Cited by 195 · see citing works

Antioxidant strategies for Alzheimer's disease

Grundman, M., & Delaney, P. (2002) · Proceedings of The Nutrition Society · doi:10.1079/pns2002146 · Cited by 193 · see citing works

Alzheimer's Disease: Redox Dysregulation As a Common Denominator for Diverse Pathogenic Mechanisms

Rommy von Bernhardi, M., & Eugenín, J. L. (2011) · Antioxidants and Redox Signaling · doi:10.1089/ars.2011.4082 · Cited by 189 · see citing works

Brain mitochondrial dysfunction as a link between Alzheimer's disease and diabetes

Moreira, P. I., Santos, M. S., Seiça, R. M. F., & Oliveira, C. R. (2007) · Journal of the Neurological Sciences · doi:10.1016/j.jns.2007.01.017 · Cited by 190 · see citing works

Anti-amyloidogenic effects of antioxidants: Implications for the prevention and therapeutics of Alzheimer's disease

Ono, K., Hamaguchi, T., Naiki, H., & Yamada, M. (2006) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · doi:10.1016/j.bbadis.2006.03.002 · Cited by 183 · see citing works

Mitochondrial UCP4 Mediates an Adaptive Shift in Energy Metabolism and Increases the Resistance of Neurons to Metabolic and Oxidative Stress

Liu, D., Chan, S. L., de Souza-Pinto, N. C., Slevin, J. R., Wersto, R. P., Zhan, M., Mustafa, K., de Cabo, R., & Mattson, M. P. (2006) · NeuroMolecular Medicine · doi:10.1385/nmm:8:3:389 · Cited by 180 · see citing works

The α-Ketoglutarate–Dehydrogenase Complex: A Mediator Between Mitochondria and Oxidative Stress in Neurodegeneration

Gibson, G. E., Blass, J. P., Beal, M. F., & Bunik, V. I. (2005) · Molecular Neurobiology · doi:10.1385/mn:31:1-3:043 · Cited by 180 · see citing works

Multiple Defects in Energy Metabolism in Alzheimers Disease

Ferreira, I. L., Resende, R., Ferreiro, E. B., Rego, A. C., & Pereira, C. (2010) · Current Drug Targets · doi:10.2174/1389450111007011193 · Cited by 177 · see citing works

Activation of PERK Signaling Attenuates Aβ-Mediated ER Stress

Lee, D. Y., Lee, K., Lee, H. J., Kim, D. H., Noh, Y. H., Yu, K., Jung, H. Y., Lee, S. H., Lee, J., Youn, Y. C., et al. (2010) · PLoS ONE · doi:10.1371/journal.pone.0010489 · Cited by 175 · see citing works

Alzheimer's disease: the pros and cons of pharmaceutical, nutritional, botanical, and stimulatory therapies, with a discussion of treatment strategies from the perspective of patients and practitioners.

Wollen, K. A. (2010) · PubMed · Cited by 168 · see citing works

Development of indole-3-propionic acid (OXIGON™) for alzheimer’s disease

Bendheim, P. E., Pöeggeler, B., Neria, E., Ziv, V., Pappolla, M. A., & Chain, D. G. (2002) · Journal of Molecular Neuroscience · doi:10.1007/s12031-002-0036-0 · Cited by 165 · see citing works

Subcellular and metabolic examination of amyloid-β peptides in Alzheimer disease pathogenesis: Evidence for Aβ25–35

Kaminsky, Y. G., Marlatt, M. W., Smith, M. A., & Kosenko, E. A. (2009) · Experimental Neurology · doi:10.1016/j.expneurol.2009.09.005 · Cited by 165 · see citing works

Involvement of endoplasmic reticulum Ca2+ release through ryanodine and inositol 1,4,5‐triphosphate receptors in the neurotoxic effects induced by the amyloid‐β peptide

Ferreiro, E. B., Oliveira, C. R., & Pereira, C. (2004) · Journal of Neuroscience Research · doi:10.1002/jnr.20135 · Cited by 152 · see citing works

Alzheimer's Disease: A Lesson from Mitochondrial Dysfunction

Moreira, P. I., Santos, M. S., & Oliveira, C. R. (2007) · Antioxidants and Redox Signaling · doi:10.1089/ars.2007.1703 · Cited by 150 · see citing works

The key role of mitochondria in Alzheimer's disease

Moreira, P. I., Cardoso, S. M., Santos, M. S., & Oliveira, C. R. (2006) · Journal of Alzheimer s Disease · doi:10.3233/jad-2006-9202 · Cited by 149 · see citing works

Synthesis of Zinc oxide nanoparticles from Marsdenia tenacissima inhibits the cell proliferation and induces apoptosis in laryngeal cancer cells (Hep-2)

Wang, Y., Zhang, Y., Guo, Y., Lu, J., Veeraraghavan, V. P., Surapaneni, K. M., Wang, C., & Yu, X. (2019) · Journal of Photochemistry and Photobiology B Biology · doi:10.1016/j.jphotobiol.2019.111624 · Cited by 139 · see citing works

Vitamin A exhibits potent antiamyloidogenic and fibril-destabilizing effects in vitro

Ono, K., Yoshiike, Y., Takashima, A., Hasegawa, K., Naiki, H., & Yamada, M. (2004) · Experimental Neurology · doi:10.1016/j.expneurol.2004.05.035 · Cited by 131 · see citing works

The α‐Ketoglutarate Dehydrogenase Complex

Sheu, K. R., & Blass, J. P. (1999) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.1999.tb07818.x · Cited by 125 · see citing works

Differential Effects of Mitochondrial Heat Shock Protein 60 and Related Molecular Chaperones to Prevent Intracellular β-Amyloid-induced Inhibition of Complex IV and Limit Apoptosis

Veereshwarayya, V., Kumar, P., Rosen, K. M., Mestril, R., & Querfurth, H. W. (2006) · Journal of Biological Chemistry · doi:10.1074/jbc.m602533200 · Cited by 125 · see citing works

Activation of the endoplasmic reticulum stress response by the amyloid-beta 1-40 peptide in brain endothelial cells.

Fonseca, A. C., Ferreiro, E., Oliveira, C., Cardoso, S., & Pereira, C. (2013) · Biochimica et Biophysica Acta · doi:10.1016/j.bbadis.2013.08.007 · Cited by 122 · see citing works

Effect of amyloid β‐peptide on permeability transition pore: A comparative study

Moreira, P. I., Santos, M. S., Moreno, A. J., Rego, A. C., & Oliveira, C. R. (2002) · Journal of Neuroscience Research · doi:10.1002/jnr.10282 · Cited by 120 · see citing works

D IET AND A POPTOSIS

Watson, W. H., Cai, J., & Jones, D. P. (2000) · Annual Review of Nutrition · doi:10.1146/annurev.nutr.20.1.485 · Cited by 118 · see citing works

Acetyl-CoA the Key Factor for Survival or Death of Cholinergic Neurons in Course of Neurodegenerative Diseases

Szutowicz, A., Bielarczyk, H., Jankowska-Kulawy, A., Pawełczyk, T., & Ronowska, A. (2013) · Neurochemical Research · doi:10.1007/s11064-013-1060-x · Cited by 116 · see citing works

Trolox and 17β-Estradiol Protect against Amyloid β-Peptide Neurotoxicity by a Mechanism That Involves Modulation of the Wnt Signaling Pathway

Quintanilla, R. A., Muñoz, F. J., Metcalfe, M., Hitschfeld, M., Olivares, G. H., Godoy, J. A., & Inestrosa, N. C. (2005) · Journal of Biological Chemistry · doi:10.1074/jbc.m411936200 · Cited by 113 · see citing works

Apolipoprotein E deficiency promotes increased oxidative stress and compensatory increases in antioxidants in brain tissue

Shea, T. B., Rogers, E. J., Ashline, D. J., Ortiz, D., & Sheu, M. (2002) · Free Radical Biology and Medicine · doi:10.1016/s0891-5849(02)01001-8 · Cited by 113 · see citing works

Amyloid β -Protein Assembly as a Therapeutic Target of Alzheimers Disease

Yamin, G., Ono, K., Inayathullah, M., & Teplow, D. B. (2008) · Current Pharmaceutical Design · doi:10.2174/138161208786404137 · Cited by 111 · see citing works

Mitochondria Dysfunction and Neurodegenerative Disorders: Cause or Consequence

Morais, V. A., & Strooper, B. D. (2010) · Journal of Alzheimer s Disease · doi:10.3233/jad-2010-100345 · Cited by 111 · see citing works

Cytosolic and mitochondrial ROS in staurosporine-induced retinal cell apoptosis

Gil‐Mohapel, J., Almeida, S., Oliveira, C. R., & Rego, A. C. (2003) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2003.08.022 · Cited by 111 · see citing works

Biosynthesis of copper oxide nanoparticles and its therapeutic efficacy against colon cancer

Tabrez, S. S. M., Khan, A. U., Mirza, A. A., Suhail, M., Jabir, N. R., Zughaibi, T. A., & Alam, M. (2022) · Nanotechnology Reviews · doi:10.1515/ntrev-2022-0081 · Cited by 104 · see citing works

Induction of cytochrome c-mediated apoptosis by amyloid β 25-35 requires functional mitochondria

Cardoso, S. M., Swerdlow, R. H., & Oliveira, C. R. (2002) · Brain Research · doi:10.1016/s0006-8993(02)02256-4 · Cited by 104 · see citing works

Vitamin E therapy in Parkinson's disease

Fariss, M. W. (2003) · Toxicology · doi:10.1016/s0300-483x(03)00158-6 · Cited by 100 · see citing works

The neuroprotective effects of tanshinone IIA on β-amyloid-induced toxicity in rat cortical neurons

Liu, T., Jin, H., Sun, Q., Xu, J., & Hu, H. (2010) · Neuropharmacology · doi:10.1016/j.neuropharm.2010.08.013 · Cited by 98 · see citing works

Apoptosis modulators in the therapy of neurodegenerative diseases

Deigner, H., Haberkorn, U., & Kinscherf, R. (2000) · Expert Opinion on Investigational Drugs · doi:10.1517/13543784.9.4.747 · Cited by 93 · see citing works

CoQ10 therapy attenuates amyloid β-peptide toxicity in brain mitochondria isolated from aged diabetic rats

Moreira, P. I., Santos, M. S., Sena, C. M., NUNES, E., Seiça, R. M. F., & Oliveira, C. R. (2005) · Experimental Neurology · doi:10.1016/j.expneurol.2005.07.012 · Cited by 93 · see citing works

Cell Degeneration Induced by Amyloid-β Peptides: Implications for Alzheimer's Disease

Pereira, C., Ferreiro, E. B., Cardoso, S. M., & Oliveira, C. R. (2004) · Journal of Molecular Neuroscience · doi:10.1385/jmn:23:1-2:097 · Cited by 88 · see citing works

Analysis of in vitro toxicity of five cell-penetrating peptides by metabolic profiling

Kilk, K., Mahlapuu, R., Soomets, U., & Langel, Ü. (2009) · Toxicology · doi:10.1016/j.tox.2009.09.016 · Cited by 87 · see citing works

Neuron-Glia Interactions as Therapeutic Targets in Neurodegeneration

Salmina, A. B. (2009) · Journal of Alzheimer s Disease · doi:10.3233/jad-2009-0988 · Cited by 86 · see citing works

Inhibition of amyloid fibrillogenesis and toxicity by a peptide chaperone

Santhoshkumar, P., & Sharma, K. K. (2004) · Molecular and Cellular Biochemistry · doi:10.1023/b:mcbi.0000049373.15558.b8 · Cited by 86 · see citing works

Pycnogenol® protects neurons from amyloid-β peptide-induced apoptosis

Peng, Q. L., Buz'Zard, A. R., & Lau, B. H. S. (2002) · Molecular Brain Research · doi:10.1016/s0169-328x(02)00263-2 · Cited by 84 · see citing works

Neuroprotective properties ofValeriana officinalis extracts

Malva, J. O., Santos, S. D., & Macedo, T. (2004) · Neurotoxicity Research · doi:10.1007/bf03033215 · Cited by 83 · see citing works

Thiamine deficiency increases β-secretase activity and accumulation of β-amyloid peptides

Zhang, Q., Yang, G., Li, W., Fan, Z., Sun, A., Luo, J., & Ke, Z. (2009) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2009.01.005 · Cited by 82 · see citing works

Alzheimer's Disease and Diabetes: An Integrative View of the Role of Mitochondria, Oxidative Stress, and Insulin

Moreira, P. I. (2012) · Journal of Alzheimer s Disease · doi:10.3233/jad-2011-111127 · Cited by 81 · see citing works

Anti-amyloidogenic therapies: strategies for prevention and treatment of Alzheimer’s disease

Hamaguchi, T., Ono, K., & Yamada, M. (2006) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-005-5599-9 · Cited by 82 · see citing works

Energy failure in astrocytes increases the vulnerability of neurons to spreading depression

Lian, X., & Stringer, J. L. (2004) · European Journal of Neuroscience · doi:10.1111/j.0953-816x.2004.03289.x · Cited by 69 · see citing works

Dysfunction of mitochondria: Implications for Alzheimer's disease

Albensi, B. C. (2019) · International review of neurobiology · doi:10.1016/bs.irn.2019.03.001 · Cited by 68 · see citing works

Interactions of oxidative stress with cellular calcium dynamics and glucose metabolism in Alzheimer's disease.

Gibson, G. (2002) · Free Radical Biology & Medicine · doi:10.1016/s0891-5849(02)00802-x · Cited by 74 · see citing works

Effects of ageing and Alzheimer’s disease on mitochondrial function of human platelets

Shi, C., Guo, K., Yew, D. T. W., Yao, Z., Forster, E. L., Wang, H., & Xu, J. (2008) · Experimental Gerontology · doi:10.1016/j.exger.2008.02.004 · Cited by 62 · see citing works

Differential toxicity of nitric oxide, aluminum, and amyloid β-peptide in SN56 cholinergic cells from mouse septum

Bielarczyk, H., Jankowska-Kulawy, A., Madziar, B., Matecki, A., Michno, A., & Szutowicz, A. (2002) · Neurochemistry International · doi:10.1016/s0197-0186(02)00097-9 · Cited by 62 · see citing works

Critical Role for Sphingosine Kinase-1 in Regulating Survival of Neuroblastoma Cells Exposed to Amyloid-β Peptide

Gomez‐Brouchet, A., Pchejetski, D., Brizuela, L., Garcia, V., Altié, M.-F., Maddelein, M., Delisle, M., & Cuvillier, O. (2007) · Molecular Pharmacology · doi:10.1124/mol.106.033738 · Cited by 59 · see citing works

Tetrahydrobiopterin causes mitochondrial dysfunction in dopaminergic cells: Implications for Parkinson's disease

Choi, H. J., Lee, S. Y., Cho, Y., No, H., Kim, S. W., & Hwang, O. (2005) · Neurochemistry International · doi:10.1016/j.neuint.2005.10.011 · Cited by 58 · see citing works

Neuroprotective effect ofH. perforatum extracts on β-amyloid-induced neurotoxicity

Silva, B. A., Dias, A. C. P., Ferreres, F., Malva, J. O., & Oliveira, C. R. (2004) · Neurotoxicity Research · doi:10.1007/bf03033214 · Cited by 58 · see citing works

Antioxidant strategies in protection against neurodegenerative disorders

Tan, D.-X., Manchester, L. C., Sainz, R. M., Mayo, J. C., Alvares, F. L., & Reiter, R. J. (2003) · Expert Opinion on Therapeutic Patents · doi:10.1517/13543776.13.10.1513 · Cited by 57 · see citing works

Peroxiredoxin II preserves cognitive function against age-linked hippocampal oxidative damage

Kim, S., Jin, M.-H., Kim, Y. S., Lee, S., Cho, Y. S., Cho, K.-J., Lee, K., Kim, Y. I., Kim, G. W., Kim, J., et al. (2009) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2009.05.017 · Cited by 56 · see citing works

Mitochondria Are Related to Synaptic Pathology in Alzheimer's Disease

Baloyannis, S. J. (2011) · International Journal of Alzheimer's Disease · doi:10.4061/2011/305395 · Cited by 66 · see citing works

β-Amyloid Peptides Are Cytotoxic to Astrocytes in Culture: A Role for Oxidative Stress

Brera, B., Serrano, A., & CEBALLOS, M. L. D. (2000) · Neurobiology of Disease · doi:10.1006/nbdi.2000.0313 · Cited by 55 · see citing works

The metabolic enhancer piracetam ameliorates the impairment of mitochondrial function and neurite outgrowth induced by ß‐amyloid peptide

Kurz, C., Ungerer, I., Lipka, U., Kirr, S., Schütt, T., Eckert, A., Leuner, K., & Müller, W. E. G. (2010) · British Journal of Pharmacology · doi:10.1111/j.1476-5381.2010.00656.x · Cited by 55 · see citing works

Efficacy of DL-α lipoic acid against systemic inflammation-induced mice: antioxidant defense system

Jesudason, E. P., Masilamoni, J. G., Walter, C. E. J., Paul, S. F. D., & Rajadas, J. (2008) · Molecular and Cellular Biochemistry · doi:10.1007/s11010-008-9748-y · Cited by 54 · see citing works

The Action of Acetyl‐l‐Carnitine on the Neurotoxicity Evoked by Amyloid Fragments and Peroxide on Primary Rat Cortical Neurones

Virmani, A., CASO, V., Spadoni, A., Rossi, S., RUSSO, F., & Gaetani, F. (2001) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.2001.tb03623.x · Cited by 51 · see citing works

Diseases of protein aggregation and the hunt for potential pharmacological agents

Wang, S. S. ‐., Wu, J. W., Yamamoto, S., & Liu, H. (2007) · Biotechnology Journal · doi:10.1002/biot.200700065 · Cited by 49 · see citing works

Molecular and biochemical trajectories from diabetes to Alzheimer’s disease: A critical appraisal

Sandhir, R., & Gupta, S. N. (2015) · World Journal of Diabetes · doi:10.4239/wjd.v6.i12.1223 · Cited by 47 · see citing works

Identification of naturally occurring spirostenols preventing β-amyloid-induced neurotoxicity

Lecanu, L., Yao, W., Teper, G., Yao, Z., Greeson, J., & Papadopoulos, V. (2003) · Steroids · doi:10.1016/j.steroids.2003.09.007 · Cited by 48 · see citing works

The spirostenol (22R, 25R)-20α-spirost-5-en-3β-yl hexanoate blocks mitochondrial uptake of Aβ in neuronal cells and prevents Aβ-induced impairment of mitochondrial function

Tillement, L., Lecanu, L., Yao, W.-G., Greeson, J., & Papadopoulos, V. (2006) · Steroids · doi:10.1016/j.steroids.2006.05.003 · Cited by 44 · see citing works

Aluminum, NO, and nerve growth factor neurotoxicity in cholinergic neurons

Szutowicz, A. (2001) · Journal of Neuroscience Research · doi:10.1002/jnr.10040 · Cited by 46 · see citing works

Cholesterol Potentiates β-Amyloid-Induced Toxicity in Human Neuroblastoma Cells: Involvement of Oxidative Stress

Ferrera, P., Mercado-Gómez, O. F., Silva-Aguilar, M., Valverde, M., & Arias, C. (2008) · Neurochemical Research · doi:10.1007/s11064-008-9623-y · Cited by 45 · see citing works

Effect of anchovy (Coilia mystus) protein hydrolysate and its Maillard reaction product on combating memory-impairment in mice

Su, G., Zhao, T., Zhao, Y., Sun‐Waterhouse, D., Qiu, C., Huang, P., & Zhao, M. (2016) · Food Research International · doi:10.1016/j.foodres.2016.01.022 · Cited by 45 · see citing works

Mitochondria as a Therapeutic Target in Alzheimers Disease and Diabetes

Moreira, P. I., Cardoso, S. M., Pereira, C., Santos, M. S., & Oliveira, C. R. (2009) · CNS & Neurological Disorders - Drug Targets · doi:10.2174/187152709789824651 · Cited by 44 · see citing works

Neutral sphingomyelinase activation in endothelial and glial cell death induced by amyloid beta-peptide

Yang, D., Yeh, C.-H., Chen, S., Xu, J., & Hsu, C. Y. (2004) · Neurobiology of Disease · doi:10.1016/j.nbd.2004.06.001 · Cited by 44 · see citing works

Protective effect of Morinda citrifolia fruits on β‐amyloid (25–35) induced cognitive dysfunction in mice: An experimental and biochemical study

Muralidharan, P., Kumar, V., & Balamurugan, G. (2009) · Phytotherapy Research · doi:10.1002/ptr.2922 · Cited by 43 · see citing works

Combining an Antioxidant‐Fortified Diet with Behavioral Enrichment Leads to Cognitive Improvement and Reduced Brain Pathology in Aging Canines

Head, E. (2007) · Annals of the New York Academy of Sciences · doi:10.1196/annals.1396.004 · Cited by 43 · see citing works

Differential effects of melatonin on amyloid-β peptide 25-35-induced mitochondrial dysfunction in hippocampal neurons at different stages of culture

Dong, W., Huang, F. P., Fan, W., Cheng, S., Chen, Y., Zhang, W., Shi, H., & He, H. (2009) · Journal of Pineal Research · doi:10.1111/j.1600-079x.2009.00734.x · Cited by 41 · see citing works

Dactylorhin B reduces toxic effects of β-amyloid fragment (25–35) on neuron cells and isolated rat brain mitochondria

Zhang, D., Zhang, Y., Liu, G.-T., & Zhang, J. (2006) · Naunyn-Schmiedeberg s Archives of Pharmacology · doi:10.1007/s00210-006-0095-9 · Cited by 40 · see citing works

The protective effect of α-crystallin against acute inflammation in mice

Masilamoni, J. G., Jesudason, E. P., Bharathi, S. N., & Rajadas, J. (2004) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · doi:10.1016/j.bbadis.2004.11.002 · Cited by 39 · see citing works

Navigating the intersection: Diabetes and Alzheimer's intertwined relationship

Kale, M. B., Bhondge, H. M., Wankhede, N. L., Shende, P. V., Thanekar, R., Aglawe, M. M., Rahangdale, S. R., Taksande, B. G., Pandit, S. B., Upaganlawar, A. B., et al. (2024) · Ageing Research Reviews · doi:10.1016/j.arr.2024.102415 · Cited by 38 · see citing works

High Expression of Nicotinamide N-Methyltransferase in Patients with Sporadic Alzheimer’s Disease

Kocinaj, A., Chaudhury, T., Uddin, M. S., Junaid, R. R., Ramsden, D. B., Hondhamuni, G., Klamt, F., Parsons, L., & Parsons, R. B. (2021) · Molecular Neurobiology · doi:10.1007/s12035-020-02259-9 · Cited by 38 · see citing works

Oxidative and hydrolytic properties of β‐amyloid

Brzyska, M., Bacia, A., & Elbaum, D. (2001) · European Journal of Biochemistry · doi:10.1046/j.1432-1327.2001.02248.x · Cited by 38 · see citing works

Mitochondrial dysfunction induced by disease relevant AβPP and tau protein mutations

Keil, U., Hauptmann, S., Bonert, A., Scherping, I., Eckert, A., & Müller, W. E. (2006) · Journal of Alzheimer s Disease · doi:10.3233/jad-2006-9206 · Cited by 36 · see citing works

Mitochondrial control of autophagic lysosomal pathway in Alzheimer's disease.

Cardoso, S., Pereira, C., Moreira, P. I., Arduíno, D. M., Esteves, A. R., & Oliveira, C. R. (2010) · Experimental Neurology · doi:10.1016/j.expneurol.2009.06.008 · Cited by 37 · see citing works

Synthesis and evaluation of arylquinones as BACE1 inhibitors, β-amyloid peptide aggregation inhibitors, and destabilizers of preformed β-amyloid fibrils

Ortega, A., Rincón, Á., Jiménez‐Aliaga, K., Bermejo‐Bescós, P., Martín‐Aragón, S., Molina, M. T., & Csákÿ, A. G. (2011) · Bioorganic & Medicinal Chemistry Letters · doi:10.1016/j.bmcl.2011.03.023 · Cited by 35 · see citing works

Mitochondrial function impairment induced by amyloid β-peptide on PC12 cells

Pereira, C., Santos, M. S., & Oliveira, C. (1998) · NeuroReport · doi:10.1097/00001756-199806010-00015 · Cited by 115 · see citing works

The Amyloid β Protein Induces Oxidative Damage of Mitochondrial DNA

Bozner, P., Grishko, V. I., LeDoux, S. P., Wilson, G. L., CHYAN, Y.-C., & Pappolla, M. A. (1997) · Journal of Neuropathology & Experimental Neurology · doi:10.1097/00005072-199712000-00010 · Cited by 107 · see citing works

P3‐187: Oxidative stress, amyloid metabolism and Alzheimer's pathogenesis: Extrapolation of a cell‐based study

Sinha, M. S. (2011) · Alzheimer s & Dementia · doi:10.1016/j.jalz.2011.05.1628

The role of oxidative stress in the toxicity induced by amyloid β-peptide in Alzheimer’s disease

Miranda, S., Opazo, C., Larrondo, L. F., Muñoz, F. J., Ruiz, F., Leighton, F., & Inestrosa, N. C. (2000) · Progress in Neurobiology · doi:10.1016/s0301-0082(00)00015-0 · Cited by 369 · see citing works

Nrf2 activation through the PI3K/GSK-3 axis protects neuronal cells from Aβ-mediated oxidative and metabolic damage

Sotolongo, K., Ghiso, J. A., & Rostagno, A. A. (2020) · Alzheimer s Research & Therapy · doi:10.1186/s13195-019-0578-9 · Cited by 72 · see citing works