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Oxidative Stress in Autism Spectrum Disorder

Bjørklund, G., Meguid, N. A., El-Bana, M. A., Tinkov, A. A., Saad, K., Dadar, M., Hemimi, M., Skalny, A. V., Hosnedlová, B., Kizek, R., et al. (2020) · Molecular Neurobiology · doi:10.1007/s12035-019-01742-2 · Cited by 323 · see citing works

Antioxidant Role of Glutathione S -Transferases: Protection Against Oxidant Toxicity and Regulation of Stress-Mediated Apoptosis

Sharma, R., Yang, Y., Sharma, A., Awasthi, S., & Awasthi, S. (2004) · Antioxidants and Redox Signaling · doi:10.1089/152308604322899350 · Cited by 319 · see citing works

Oxidative stress mediates tau-induced neurodegeneration in Drosophila

Dias-Santagata, D., Fulga, T. A., Duttaroy, A., & Feany, M. B. (2007) · Journal of Clinical Investigation · doi:10.1172/jci28769 · Cited by 318 · see citing works

4-Hydroxynonenal and neurodegenerative diseases

Žarković, K. (2003) · Molecular Aspects of Medicine · doi:10.1016/s0098-2997(03)00024-4 · Cited by 315 · see citing works

Redox Control of Microglial Function: Molecular Mechanisms and Functional Significance

Rojo, A. I., McBean, G. J., Cindrić, M., Egea, J., López, M. G., Rada, P., Žarković, N., & Cuadrado, A. (2014) · Antioxidants and Redox Signaling · doi:10.1089/ars.2013.5745 · Cited by 313 · see citing works

The interplay between inflammation, oxidative stress, DNA damage, DNA repair and mitochondrial dysfunction in depression

Czarny, P., Wigner, P., Galecki, P., & Sliwinski, T. (2018) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2017.06.036 · Cited by 310 · see citing works

A Novel Function of Monomeric Amyloid β-Protein Serving as an Antioxidant Molecule against Metal-Induced Oxidative Damage

Zou, K., Gong, J.-S., Yanagisawa, K., & Michikawa, M. (2002) · The Journal of Neuroscience · doi:10.1523/jneurosci.22-12-04833.2002 · Cited by 305 · see citing works

Oxidative stress, protein modification and Alzheimer disease

Tramutola, A., Lanzillotta, C., Perluigi, M., & Butterfield, D. A. (2017) · Brain Research Bulletin · doi:10.1016/j.brainresbull.2016.06.005 · Cited by 303 · see citing works

Roles of the lipid peroxidation product 4-hydroxynonenal in obesity, the metabolic syndrome, and associated vascular and neurodegenerative disorders

Mattson, M. P. (2009) · Experimental Gerontology · doi:10.1016/j.exger.2009.07.003 · Cited by 303 · see citing works

Formation and signaling actions of electrophilic lipids

Schopfer, F. J., Cipollina, C., & Freeman, B. A. (2011) · Chemical Reviews · doi:10.1021/cr200131e · Cited by 299 · see citing works

Involvements of the lipid peroxidation product, HNE, in the pathogenesis and progression of Alzheimer's disease☆

Butterfield, D. A., Lange, M. L. B., & Rukhsana Sultana, A. (2010) · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids · doi:10.1016/j.bbalip.2010.02.005 · Cited by 298 · see citing works

Alzheimer disease, the two-hit hypothesis: An update

Zhu, X., Lee, H., Perry, G. L., & Smith, M. A. (2006) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · doi:10.1016/j.bbadis.2006.10.014 · Cited by 292 · see citing works

Increased DNA Oxidation and Decreased Levels of Repair Products in Alzheimer's Disease Ventricular CSF

Lovell, M. A., Gabbita, S. P., & Markesbery, W. R. (1999) · Journal of Neurochemistry · doi:10.1046/j.1471-4159.1999.0720771.x · Cited by 291 · see citing works

Oxidative damage and the Nrf2-ARE pathway in neurodegenerative diseases

Gan, L., & Johnson, J. A. (2014) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · doi:10.1016/j.bbadis.2013.12.011 · Cited by 288 · see citing works

Glutathione peroxidase 4: a new player in neurodegeneration?

Cardoso, B. R., Hare, D. J., Bush, A. I., & Roberts, B. R. (2016) · Molecular Psychiatry · doi:10.1038/mp.2016.196 · Cited by 281 · see citing works

The relationship between oxidative/nitrative stress and pathological inclusions in Alzheimer’s and Parkinson’s diseases1,2 11Guest Editors: Mark A. Smith and George Perry 22This article is part of a series of reviews on “Causes and Consequences of Oxidative Stress in Alzheimer’s Disease.” The full list of papers may be found on the homepage of the journal.

Giasson, B. I., Ischiropoulos, H., Lee, V. M. ‐., & Trojanowski, J. Q. (2002) · Free Radical Biology and Medicine · doi:10.1016/s0891-5849(02)00804-3 · Cited by 281 · see citing works

Ferulic acid ethyl ester protects neurons against amyloid β‐ peptide(1–42)‐induced oxidative stress and neurotoxicity: relationship to antioxidant activity

Rukhsana Sultana, A., Ravagna, A., Abdul, H. M., Calabrese, V., & Butterfield, D. A. (2005) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2004.02899.x · Cited by 276 · see citing works

Lipid peroxidation is an early event in the brain in amnestic mild cognitive impairment

Markesbery, W. R., Kryscio, R. J., Lovell, M. A., & Morrow, J. D. (2005) · Annals of Neurology · doi:10.1002/ana.20629 · Cited by 272 · see citing works

Shaping the Nrf2-ARE-related pathways in Alzheimer’s and Parkinson’s diseases

Fão, L., Mota, S. I., & Rego, A. C. (2019) · Ageing Research Reviews · doi:10.1016/j.arr.2019.100942 · Cited by 270 · see citing works

The critical role of methionine 35 in Alzheimer's amyloid β-peptide (1–42)-induced oxidative stress and neurotoxicity

Butterfield, D. A., & Debra Boyd-kimball, A. (2004) · Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics · doi:10.1016/j.bbapap.2004.10.014 · Cited by 267 · see citing works

Lipid peroxidation and cell cycle signaling: 4-hydroxynonenal, a key molecule in stress mediated signaling.

Yang, Y., Sharma, R., Sharma, A., Awasthi, S., & Awasthi, S. (2003) · Acta Biochimica Polonica · doi:10.18388/abp.2003_3689 · Cited by 258 · see citing works

Amyloid β‐Peptide(1‐42) Contributes to the Oxidative Stress and Neurodegeneration Found in Alzheimer Disease Brain

Butterfield, D. A., & Debra Boyd-kimball, A. (2004) · Brain Pathology · doi:10.1111/j.1750-3639.2004.tb00087.x · Cited by 263 · see citing works

Protein Oxidation and Lipid Peroxidation in Brain of Subjects with Alzheimer's Disease: Insights into Mechanism of Neurodegeneration from Redox Proteomics

Rukhsana Sultana, A., Marzia Perluigi, A., & Butterfield, D. A. (2006) · Antioxidants and Redox Signaling · doi:10.1089/ars.2006.8.2021 · Cited by 261 · see citing works

Increased oxidative damage in nuclear and mitochondrial DNA in mild cognitive impairment

Wang, J., Markesbery, W. R., & Lovell, M. A. (2006) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2005.03615.x · Cited by 260 · see citing works

Decrease in Peptide Methionine Sulfoxide Reductase in Alzheimer's Disease Brain

Gabbita, S. P., Aksenov, M. Y., Lovell, M. A., & Markesbery, W. R. (1999) · Journal of Neurochemistry · doi:10.1046/j.1471-4159.1999.0731660.x · Cited by 256 · see citing works

Role of 4-hydroxy-2-nonenal (HNE) in the pathogenesis of alzheimer disease and other selected age-related neurodegenerative disorders

Di Domenico, F., Tramutola, A., & Butterfield, D. A. (2017) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2016.10.490 · Cited by 253 · see citing works

Increased oxidative stress in Alzheimer's disease as assessed with 4-hydroxynonenal but not malondialdehyde

McGrath, L. T. (2001) · QJM · doi:10.1093/qjmed/94.9.485 · Cited by 253 · see citing works

4-Hydroxynonenal As a Biological Signal: Molecular Basis and Pathophysiological Implications

Parola, M., Bellomo, G., Robino, G., Barrera, G., & Dianzani, M. U. (1999) · Antioxidants and Redox Signaling · doi:10.1089/ars.1999.1.3-255 · Cited by 250 · see citing works

Biomarkers of oxidative and nitrosative damage in Alzheimer's disease and mild cognitive impairment

Mangialasche, F., Polidori, M. C., Monastero, R., Ercolani, S., Camarda, C., Cecchetti, R., & Mecocci, P. (2009) · Ageing Research Reviews · doi:10.1016/j.arr.2009.04.002 · Cited by 247 · see citing works

Astrocyte dysfunction in Alzheimer disease

Acosta, C., Anderson, H. D., & Anderson, C. M. (2017) · Journal of Neuroscience Research · doi:10.1002/jnr.24075 · Cited by 248 · see citing works

Elevated protein-bound levels of the lipid peroxidation product, 4-hydroxy-2-nonenal, in brain from persons with mild cognitive impairment

Butterfield, D. A., Reed, T., Perluigi, M., De Marco, C., Coccia, R., Cini, C., & Sultana, R. (2006) · Neuroscience Letters · doi:10.1016/j.neulet.2005.12.017 · Cited by 246 · see citing works

The Nrf2-ARE Pathway: A Valuable Therapeutic Target for the Treatment of Neurodegenerative Diseases

Gururaj Joshi, A., & Johnson, J. A. (2012) · Recent Patents on CNS Drug Discovery · doi:10.2174/157488912803252023 · Cited by 246 · see citing works

On the role of 4-hydroxynonenal in health and disease

Csala, M., Kardon, T., Legeza, B., Lizák, B., Mandl, J., Margittai, É., Puskás, F., Száraz, P., Szelényi, P., & Bánhegyi, G. (2015) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · doi:10.1016/j.bbadis.2015.01.015 · Cited by 244 · see citing works

Isoprostanes and related products of lipid peroxidation in neurodegenerative diseases

Montine, K. S., Quinn, J. F., Zhang, J., Fessel, J. P., Roberts, L. J., Morrow, J. D., & Montine, T. J. (2003) · Chemistry and Physics of Lipids · doi:10.1016/j.chemphyslip.2003.10.010 · Cited by 242 · see citing works

Free Radicals: Key to Brain Aging and Heme Oxygenase as a Cellular Response to Oxidative Stress

Poon, H. F., Calabrese, V., Scapagnini, G., & Butterfield, D. A. (2004) · The Journals of Gerontology Series A · doi:10.1093/gerona/59.5.m478 · Cited by 235 · see citing works

4-Hydroxy-nonenal—A Bioactive Lipid Peroxidation Product

Schaur, R. J., Siems, W., Bresgen, N., & Eckl, P. (2015) · Biomolecules · doi:10.3390/biom5042247 · Cited by 231 · see citing works

4-Hydroxynonenal in the Pathogenesis and Progression of Human Diseases

Shoeb, M., Ansari, N., Srivastava, S., & Ramana, K. (2013) · Current Medicinal Chemistry · doi:10.2174/09298673113209990181 · Cited by 230 · see citing works

4-Hydroxy-2-nonenal, a reactive product of lipid peroxidation, and neurodegenerative diseases: a toxic combination illuminated by redox proteomics studies

Perluigi, M., Coccia, R., & Butterfield, D. A. (2012) · Antioxidants &amp; Redox Signaling · doi:10.1089/ars.2011.4406 · Cited by 229 · see citing works

Nitrosative Stress, Cellular Stress Response, and Thiol Homeostasis in Patients with Alzheimer's Disease

Calabrese, V., Rukhsana Sultana, A., Scapagnini, G., Guagliano, E., Sapienza, M. A., Bella, R., Kański, J., Pennisi, G., Mancuso, C., Stella, A. M. G., et al. (2006) · Antioxidants and Redox Signaling · doi:10.1089/ars.2006.8.1975 · Cited by 227 · see citing works

Oxidatively modified proteins in Alzheimer’s disease (AD), mild cognitive impairment and animal models of AD: role of Abeta in pathogenesis

Sultana, R., Perluigi, M., & Butterfield, D. A. (2009) · Acta Neuropathologica · doi:10.1007/s00401-009-0517-0 · Cited by 215 · see citing works

Benefits from Dietary Polyphenols for Brain Aging and Alzheimer’s Disease

Rossi, L. C., Mazzitelli, S., Arciello, M., Capo, C. R., & Rotilio, G. (2008) · Neurochemical Research · doi:10.1007/s11064-008-9696-7 · Cited by 216 · see citing works

Hypobaric hypoxia induces oxidative stress in rat brain

Maiti, P., Singh, S. B., Sharma, A. K., Muthuraju, S., Banerjee, P. K., & Ilavazhagan, G. (2006) · Neurochemistry International · doi:10.1016/j.neuint.2006.06.002 · Cited by 215 · see citing works

Mitochondrial dysfunction, oxidative stress and neurodegeneration

Mancuso, M., Coppedè, F., Migliore, L., Siciliano, G., & Murri, L. (2006) · Journal of Alzheimer s Disease · doi:10.3233/jad-2006-10110 · Cited by 209 · see citing works

Learning ability in aged beagle dogs is preserved by behavioral enrichment and dietary fortification: a two-year longitudinal study

Milgram, N. W., Head, E., Zicker, S. C., Ikeda-Douglas, C. J., Murphey, H. L., Muggenburg, B. A., Siwak, C. T., Tapp, D., & Cotman, C. W. (2004) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2004.02.014 · Cited by 208 · see citing works

Increased levels of 4-hydroxynonenal and acrolein in the brain in preclinical Alzheimer disease

Bradley, M. A., Markesbery, W. R., & Lovell, M. A. (2010) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2010.02.016 · Cited by 193 · see citing works

Elevated 4-Hydroxynonenal in Ventricular Fluid in Alzheimer’s Disease

Lovell, M. A., Ehmann, W. D., Mattson, M. P., & Markesbery, W. R. (1997) · Neurobiology of Aging · doi:10.1016/s0197-4580(97)00108-5 · Cited by 413 · see citing works

4‐Hydroxynonenal‐Derived Advanced Lipid Peroxidation End Products Are Increased in Alzheimer's Disease

Sayre, L., Zelasko, D. A., Harris, P. L. R., Perry, G., Salomon, R. G., & Smith, M. A. (1997) · Journal of Neurochemistry · doi:10.1046/j.1471-4159.1997.68052092.x · Cited by 1,032 · see citing works

Elevated levels of 4-hydroxynonenal-histidine Michael adduct in the hippocampi of patients with Alzheimer's disease

Fukuda, M., Kanou, F., Shimada, N., Sawabe, M., Saito, Y., Murayama, S., Hashimoto, M., Maruyama, N., & Ishigami, A. (2009) · Biomedical Research · doi:10.2220/biomedres.30.227 · Cited by 66 · see citing works

Involvements of the lipid peroxidation product, HNE, in the pathogenesis and progression of Alzheimer's disease☆

Butterfield, D. A., Lange, M. L. B., & Rukhsana Sultana, A. (2010) · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids · doi:10.1016/j.bbalip.2010.02.005 · Cited by 298 · see citing works

Potentiation of amyloid-β-peptide neurotoxicity by 4-hydroxynonenal and 24-hydroxycholesterol

Gamba, P., Testa, G., Gargiulo, S., Sottero, B., Scipio, F. D., Sprio, A. E., Salamone, P., Berta, G. N., Leonarduzzi, G., & Poli, G. (2012) · Institutional Research Information System University of Turin (University of Turin)