Cited by 268Diabetes and associated disordersDiabetes Management and ResearchDiabetes, Cardiovascular Risks, and Lipoproteins

SEARCH for Diabetes in Youth: a multicenter study of the prevalence, incidence and classification of diabetes mellitus in youth

The SEARCH Study Group·2004·Controlled Clinical Trials

Abstract

SEARCH for Diabetes in Youth is an observational, multicenter study focusing on physician-diagnosed diabetes in individuals <20 years old. The study will estimate the population prevalence and incidence of diabetes by type, age, gender, and ethnicity and develop practical approaches to diabetes classification in 5 million children ( approximately 6% of the <20 U.S. population) with wide ethnic and socioeconomic representation from four geographically defined populations and two health plans. An estimated 6000 prevalent and 800 incident diabetes cases per year will be identified with annual follow-up. Cases will be ascertained through clinical and nonclinical resources or partnerships at each site. Data collection involves patient interviews, physical examinations, laboratory measurements (diabetes autoantibodies, fasting/stimulating C-peptide, hemoglobin A1c, blood glucose, lipids, urine albumin, creatinine), medical records reviews, and documentation of risk factors for complications and processes of care.

Integrity signals

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Crossref · 10.1016/j.cct.2004.08.002

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  • Atypical diabetes is becoming increasingly difficult to precisely define in the absence of a definitive set of tests for either type 1 or type 2 diabetes.

    “although admittedly, atypical diabetes is becoming increasingly dif fi cult to precisely de fi ne in the absence of a de fi nitive set of tests for either type of diabetes (158 -160,163 -169)”

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Authors
The SEARCH Study Group
Corresponding author
The SEARCH Study Group
Venue
Controlled Clinical Trials
Publisher
Elsevier BV
Published
2004-10
Volume
25
Issue
5
Pages
458-471
ISSN
0197-2456 (ISSN-L)
OpenAlex
W4229611233
Cited by
268
References
20
Citations by year
2026: 1 · 2025: 7 · 2024: 12 · 2023: 16 · 2022: 13 · 2021: 7 · 2020: 15 · 2019: 11 · 2018: 11 · 2017: 11 · 2016: 12 · 2015: 13 · 2014: 24 · 2013: 22 · 2012: 20
FWCI
2.86
Type
journal article
Language
en
Open access
closed
Locations
  • Controlled Clinical Trials (publishedVersion)
  • PubMed (publishedVersion)
Funders
  • Kaiser Permanente
  • U.S. Public Health Service (PA 00097)
  • NIH Clinical Center
Topics
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Diabetes and associated disorders
  • Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Management and Research
  • Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes, Cardiovascular Risks, and Lipoproteins
Keywords
diabetes mellitus, youth, children, prevalence, incidence, diabetes classification, type 1 diabetes, type 2 diabetes, diabetes autoantibodies, C-peptide, HbA1c, diabetes complications, risk factors, health plans
MeSH terms
Adolescent, Carrier Proteins, Child, Diabetes Mellitus, Female, Follow-Up Studies, Humans, Male, Mass Screening, Multicenter Studies as Topic, Incidence, Prevalence

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