Fluoroacetate and fluorocitrate: Mechanism of action

Glutamine, glutamate and gaba in the central nervous system

Teelken, A. W. (1986) · Clinical Neurology and Neurosurgery · doi:10.1016/0303-8467(86)90020-x · Cited by 672 · see citing works

An In Vivo Model for Studying Function of Brain Tissue Temporarily Devoid of Glial Cell Metabolism: The Use of Fluorocitrate

Paulsen, R. E., Contestabile, A., Villani, L., & Fonnum, F. (1987) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.1987.tb05674.x · Cited by 262 · see citing works

Compartmentation of Amino Acid Metabolism

Berl, S., & Clarke, D. D. (1969) · Springer eBooks · doi:10.1007/978-1-4899-7321-4_19 · Cited by 211 · see citing works

Regional distribution of astrocytes with intense immunoreactivity for glutamate dehydrogenase in rat brain: implications for neuron-glia interactions in glutamate transmission

Aoki, C. J., Milner, T., Sheu, K. ‐. R., Jp, B., & Pickel, V. M. (1987) · Journal of Neuroscience · doi:10.1523/jneurosci.07-07-02214.1987 · Cited by 157 · see citing works

Acetate and fluoroacetate as possible markers for glial metabolism in vivo

Muir, D. A., Berl, S., & Clarke, D. D. (1986) · Brain Research · doi:10.1016/0006-8993(86)90231-3 · Cited by 140 · see citing works

Tricarboxylic acid-cycle metabolism in brain. Effect of fluoroacetate and fluorocitrate on the labelling of glutamate aspartate, glutamine and γ-amino butyrate

Clarke, D. D., Nicklas, W. J., & Berl, S. (1970) · Biochemical Journal · doi:10.1042/bj1200345 · Cited by 118 · see citing works

Fluorinated Substrate Analogs: Routes of Metabolism and Selective Toxicity

Walsh, C. T. (1983) · Advances in enzymology and related areas of molecular biology/Advances in enzymology and related subjects · doi:10.1002/9780470123010.ch3 · Cited by 50 · see citing works

Enzymatic defluorination and metabolism of fluoroacetate, fluoroacetamide, fluoroethanol, and (-)-erythro-fluorocitrate in rats and mice examined by fluorine-19 and carbon-13 NMR

Tecle, B., & Casida, J. E. (1989) · Chemical Research in Toxicology · doi:10.1021/tx00012a012 · Cited by 49 · see citing works

Seizures induced by fluoroacetic acid and fluorocitric acid may involve chelation of divalent cations in the spinal cord

Hornfeldt, C. S., & Larson, A. A. (1990) · European Journal of Pharmacology · doi:10.1016/0014-2999(90)90170-b · Cited by 48 · see citing works

Studies with Specific Enzyme Inhibitors

Dummel, R. J., & Kun, É. (1969) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)91718-7 · Cited by 44 · see citing works

FLUOROACETATE AND THE METABOLISM OF AMMONIA IN BRAIN

Lahiri, S., & Quastel, J. (1963) · Biochemical Journal · doi:10.1042/bj0890157 · Cited by 41 · see citing works

Enzymatic formation of glutathione-citryl thioester by a mitochondrial system and its inhibition by (-)erythrofluorocitrate

Kun, E., Kirsten, E., & Sharma, M. L. (1977) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.74.11.4942 · Cited by 35 · see citing works

Absolute configuration of the isomer of fluorocitrate that inhibits aconitase

Stallings, W. C., Monti, C. T., Belvedere, J. F., et al. (1980) · Archives of Biochemistry and Biophysics · doi:10.1016/0003-9861(80)90154-x · Cited by 25 · see citing works

Fluorocitrate inhibition of aconitase. Reversibility of the inactivation

Villafranca, J. J., & Platus, E. (1973) · Biochemical and Biophysical Research Communications · doi:10.1016/s0006-291x(73)80021-x · Cited by 24 · see citing works

The effect of injections of fluorocitrate into the brains of rats

Morselli, P. L., Garattini, S. K., Marcucci, F., et al. (1968) · Biochemical Pharmacology · doi:10.1016/0006-2952(68)90323-7 · Cited by 24 · see citing works

Stereochemical studies on the hydration of monofluorofumarate and 2,3-difluorofumarate by fumarase

Marletta, M. A., Cheung, Y.-F., & Walsh, C. T. (1982) · Biochemistry · doi:10.1021/bi00540a010 · Cited by 22 · see citing works

Some Metabolic Aspects of Fluoroacetate Especially Related to Fluorocitrate

Peters, R. A. (1972) · Novartis Foundation symposium · doi:10.1002/9780470719855.ch4 · Cited by 20 · see citing works

Fluorofumarate—A substrate for fumarate hydratase

Clarke, D. D., Nicklas, W. J., & Palumbo, J. C. (1968) · Archives of Biochemistry and Biophysics · doi:10.1016/0003-9861(68)90122-7 · Cited by 18 · see citing works

Isolation of 2-fluorocitrate produced by in vivo dealkylation of 29-fluorostigmasterol in an insect.

Prestwich, G. D., Yamaoka, R., Phirwa, S., et al. (1984) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)90616-2 · Cited by 16 · see citing works

Note upon the behaviour of rat brain tissue treated with fluoroacetate in vitro

Peters, R. A., & Shorthouse, M. (1966) · Biochemical Pharmacology · doi:10.1016/0006-2952(66)90247-4 · Cited by 11 · see citing works

Fluoroaconitates: Wittig Reaction of Oxalofluoroacetic Acid Esters

CANTACUZENE, D., Wakselman, C., & MASSOUDI, H. (1984) · Synthetic Communications · doi:10.1080/00397918408059635 · Cited by 8 · see citing works

Triethyl α-Fluoroaconitate

BERGMANN, E. D., & Shahak, I. (1960) · Nature · doi:10.1038/185529b0 · Cited by 4 · see citing works

STUDIES ON THE TOXIC ISOMER OF FLUOROCITRATE

Hudick, J. P. (1972) · Fordham Research Commons (Fordham University) · Cited by 1 · see citing works

Development of a gut microbe–targeted nonlethal therapeutic to inhibit thrombosis potential

Roberts, A. B., Gu, X., Buffa, J. A., Hurd, A. G., Wang, Z., Zhu, W., Gupta, N., Skye, S. M., Cody, D. B., Levison, B. S., et al. (2018) · Nature Medicine · doi:10.1038/s41591-018-0128-1 · Cited by 552 · see citing works

Norepinephrine triggers release of glial ATP to increase postsynaptic efficacy

Gordon, G. R. J., Baimoukhametova, D. V., Hewitt, S. A., Rajapaksha, W. R. A. K. J. S., Fisher, T. E., & Bains, J. S. (2005) · Nature Neuroscience · doi:10.1038/nn1498 · Cited by 374 · see citing works

Brain glycogen re-awakened

Brown, A. M. (2004) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2004.02421.x · Cited by 308 · see citing works

The Glutamine–Glutamate/GABA Cycle: Function, Regional Differences in Glutamate and GABA Production and Effects of Interference with GABA Metabolism

Walls, A. B., Waagepetersen, H. S., Bak, L. K., Schousboe, A., & Sonnewald, U. (2015) · Neurochemical Research · doi:10.1007/s11064-014-1473-1 · Cited by 223 · see citing works

Neuronal P2X7 Receptors Revisited: Do They Really Exist?

Illes, P., Khan, T. M., & Rubini, P. (2017) · The Journal of Neuroscience · doi:10.1523/jneurosci.3103-16.2017 · Cited by 179 · see citing works

Roles of astrocytes and microglia in seizure-induced aberrant neurogenesis in the hippocampus of adult rats

Yang, F., Liu, Z., Chen, J., Zhang, S., Quan, Q., Huang, Y., & Jiang, W. (2010) · Journal of Neuroscience Research · doi:10.1002/jnr.22224 · Cited by 80 · see citing works

Potentiation of the glutamatergic synaptic input to rat locus coeruleus neurons by P2X7 receptors

Khakpay, R., Polster, D., Köles, L., Skorinkin, A., Szabo, B., Wirkner, K., & Illes, P. (2010) · Purinergic Signalling · doi:10.1007/s11302-010-9198-3 · Cited by 24 · see citing works

The aconitase of yeast. I. Induction and stabilization of yeast aconitase activity by fluorocitrate.

Suzuki, T., Akiyama, S.-I., Yamazaki, O., et al. (1975) · Agricultural and Biological Chemistry · doi:10.1271/bbb1961.39.97 · Cited by 2 · see citing works

Localization of the Enzymatic Block in Kidneys of Rats Treated with Fluoroacetate

Busch, H., & POTTER, V. R. (1952) · Experimental Biology and Medicine · doi:10.3181/00379727-81-19814 · Cited by 6 · see citing works

TOXIC CHARAC TERISTICS OF FLUOROCITRATE, THE T OXIC METABOLITE OF COMPOUND 1080

Savarie, P. J. (1984) · Lincoln (University of Nebraska) · Cited by 15 · see citing works

The inhibition of aconitase by ‘inhibitor fractions' isolated from tissues poisoned with fluoroacetate

(1952) · Biochemical Journal · doi:10.1042/bj0510743g · Cited by 1 · see citing works

A further study of the inhibition of aconitase by ‘inhibitor fraction’ isolated from tissues poisoned with fluoroacetate

Peters, R. A., & Wilson, T. H. (1952) · Biochimica et Biophysica Acta · doi:10.1016/0006-3002(52)90166-2 · Cited by 25 · see citing works